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methylphenidate and Alcohol Abuse

methylphenidate has been researched along with Alcohol Abuse in 35 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
"The rate of increase in plasma GH level was blunted for adolescents with alcohol abuse compared to the control group, after methylphenidate administration [ t=-2."3.72Neuroendocrine and behavioral responses to dopaminergic agonists in adolescents with alcohol abuse. ( Brady, KT; Liao, J; Middaugh, L; Sallee, FR; Sethuraman, G; Upadhyaya, HP; Wharton, M, 2003)
"Evaluations for ADHD and substance abuse were completed."2.39The dual diagnosis of attention-deficit/hyperactivity disorder and substance abuse: case reports and literature review. ( Isaacson, JH; Musial, J; Schubiner, H; Tzelepis, A; Warbasse, LH; Zacharek, M, 1995)
"A minority of alcohol abusers develop severe cerebral dysfunction in the form of Wernicke-Korsakoff syndrome."2.35Chronic cerebral effects of alcohol and drug abuse. ( Grant, I; Mohns, L, 1975)
"Diagnoses of SUD and alcohol abuse were obtained from The Danish Psychiatric Central Register."1.40ADHD, stimulant treatment in childhood and subsequent substance abuse in adulthood - a naturalistic long-term follow-up study. ( Dalsgaard, S; Frydenberg, M; Mortensen, PB; Thomsen, PH, 2014)
"Methylphenidate (MPH) is a prescription stimulant drug with known abuse potential; however, little is known about its patterns of misuse or the characteristics of its abusers."1.33Characteristics of methylphenidate misuse in a university student sample. ( Barrett, SP; Bordy, LE; Darredeau, C; Pihl, RO, 2005)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199015 (42.86)18.7374
1990's4 (11.43)18.2507
2000's11 (31.43)29.6817
2010's5 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Volkow, ND3
Tomasi, D1
Wang, GJ3
Telang, F2
Fowler, JS3
Logan, J3
Maynard, LJ1
Wong, CT1
Looby, A1
De Young, KP1
Earleywine, M1
Dalsgaard, S1
Mortensen, PB1
Frydenberg, M1
Thomsen, PH1
Martín Fernández-Mayoralas, D1
Fernández-Jaén, A1
Franke, AG1
Schwarze, CE1
Christmann, M1
Bonertz, C1
Hildt, E1
Lieb, K1
Barrett, SP2
Pihl, RO2
Upadhyaya, HP1
Brady, KT1
Liao, J1
Sethuraman, G1
Middaugh, L1
Wharton, M1
Sallee, FR1
Teter, CJ1
McCabe, SE1
Boyd, CJ1
Guthrie, SK1
HARTERT, D1
BROWNE-MAYERS, AN1
ROGERS, LL1
PELTON, RB1
WILLIAMS, MB1
ROBERTS, HJ2
SCOGIN, JT1
DOBSON, HL1
Darredeau, C1
Bordy, LE1
Wolf, U1
Golombek, U1
Diefenbacher, A1
Wu, LT1
Pilowsky, DJ1
Schlenger, WE1
Galvin, DM1
Novak, SP1
Kroutil, LA1
Williams, RL1
Van Brunt, DL1
Caci, H1
Baylé, F1
Jayne, M1
Ma, Y1
Pradhan, K1
Wong, C1
Heiman, EM1
Schubiner, H1
Tzelepis, A1
Isaacson, JH1
Warbasse, LH1
Zacharek, M1
Musial, J1
Hitzemann, R1
Ding, YS1
Pappas, N1
Shea, C1
Piscani, K1
Durst, R1
Rebaudengo-Rosca, P1
Bridgeford, D1
Arciniegas, DB1
Batkis, M1
Sandberg, E1
Beresford, TP1
Weisfelt, M1
Schrier, AC1
de Leeuw, MC1
Janowsky, DS2
Leichner, P1
Parker, D1
Judd, L1
Huey, L1
Clopton, P1
Huapaya, LV1
Wood, DR1
Reimherr, FW1
Wender, PH1
Johnson, GE1
Leichner, PP1
Reid, AE1
Grant, I1
Mohns, L1
Jaffe, SL1
Miller, TP1
Taylor, JL1
Tinklenberg, JR1
Ditman, KS2
Moss, T2
Forgy, E1
Zunin, L1
Funk, W1
Lynch, R1
Forgy, EW1
Zunin, LM1
Lynch, RD1
Funk, WA1

Reviews

4 reviews available for methylphenidate and Alcohol Abuse

ArticleYear
[Alcoholic foetopathy: an update].
    Revista de neurologia, 2011, Mar-01, Volume: 52 Suppl 1

    Topics: Adrenergic Uptake Inhibitors; Alcoholism; Atomoxetine Hydrochloride; Central Nervous System Stimulan

2011
The dual diagnosis of attention-deficit/hyperactivity disorder and substance abuse: case reports and literature review.
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:4

    Topics: Adult; Alcoholism; Attention Deficit Disorder with Hyperactivity; Comorbidity; Diagnosis, Dual (Psyc

1995
[Hyperactive behavior in adults; possibly attention deficit/hyperactivity disorder (ADHD)].
    Nederlands tijdschrift voor geneeskunde, 2001, Aug-04, Volume: 145, Issue:31

    Topics: Adult; Alcoholism; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants;

2001
Chronic cerebral effects of alcohol and drug abuse.
    The International journal of the addictions, 1975, Volume: 10, Issue:5

    Topics: Alcoholism; Amphetamines; Barbiturates; Brain Diseases; Cannabis; Cerebrovascular Disorders; Cocaine

1975

Trials

5 trials available for methylphenidate and Alcohol Abuse

ArticleYear
Challenging expectancies to prevent nonmedical prescription stimulant use: a randomized, controlled trial.
    Drug and alcohol dependence, 2013, Sep-01, Volume: 132, Issue:1-2

    Topics: Adolescent; Alcoholism; Central Nervous System Stimulants; Data Interpretation, Statistical; Female;

2013
The effect of methylphenidate on serum growth hormone: influence of antipsychotic drugs and diagnosis.
    Archives of general psychiatry, 1978, Volume: 35, Issue:11

    Topics: Adjustment Disorders; Adolescent; Adult; Alcoholism; Antipsychotic Agents; Bipolar Disorder; Blood P

1978
Diagnosis and treatment of minimal brain dysfunction in adults: a preliminary report.
    Archives of general psychiatry, 1976, Volume: 33, Issue:12

    Topics: Adult; Alcoholism; Antisocial Personality Disorder; Anxiety; Attention Deficit Disorder with Hyperac

1976
A comparison of assessment techniques measuring the effects of methylphenidate, secobarbital, diazepam and diphenhydramine in abstinent alcoholics.
    Neuropsychobiology, 1988, Volume: 19, Issue:2

    Topics: Adult; Alcoholism; Arousal; Attention; Diazepam; Diphenhydramine; Discrimination Learning; Humans; M

1988
Dimensions of LSD, methylphenidate and chlordiazepoxide experiences.
    Psychopharmacologia, 1969, Volume: 14, Issue:1

    Topics: Alcoholism; Chlordiazepoxide; Clinical Trials as Topic; Emotions; Hallucinations; Humans; Lysergic A

1969

Other Studies

26 other studies available for methylphenidate and Alcohol Abuse

ArticleYear
Predominance of D2 receptors in mediating dopamine's effects in brain metabolism: effects of alcoholism.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Mar-06, Volume: 33, Issue:10

    Topics: Adult; Alcoholism; Analysis of Variance; Brain; Brain Mapping; Carbon Radioisotopes; Cardiovascular

2013
ADHD, stimulant treatment in childhood and subsequent substance abuse in adulthood - a naturalistic long-term follow-up study.
    Addictive behaviors, 2014, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Age Factors; Alcoholism; Attention Deficit Disorder with Hyperactivity; Central N

2014
[Characteristics of university students using stimulants for cognitive enhancement: a pilot study].
    Psychiatrische Praxis, 2012, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Alcoholism; Amphetamines; Case-Control Studies; Central Nervous System Stimulants

2012
Oral methylphenidate-alcohol co-abuse.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:6

    Topics: Administration, Oral; Adult; Alcoholism; Central Nervous System Stimulants; Comorbidity; Female; Hum

2002
Neuroendocrine and behavioral responses to dopaminergic agonists in adolescents with alcohol abuse.
    Psychopharmacology, 2003, Volume: 166, Issue:2

    Topics: Adolescent; Adult; Affect; Alcoholism; Dopamine Agonists; Female; Human Growth Hormone; Humans; Male

2003
Illicit methylphenidate use in an undergraduate student sample: prevalence and risk factors.
    Pharmacotherapy, 2003, Volume: 23, Issue:5

    Topics: Alcoholism; Central Nervous System Stimulants; Data Collection; Female; Humans; Illicit Drugs; Inter

2003
The use of methylphenidate (ritalin) hydrochloride in alcoholism; preliminary report on its diagnostic and therapeutic use.
    Journal of the American Medical Association, 1958, Apr-19, Volume: 166, Issue:16

    Topics: Alcoholism; Methylphenidate; Salts

1958
Effect of behavior-altering drugs on alcohol consumption by rats.
    Texas reports on biology and medicine, 1958, Volume: 16, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Animals; Methylphenidate; Piperidines; Rats; Tranquilizing Agents

1958
Managing alcoholics with Serpasil and Ritalin.
    Virginia medical monthly, 1961, Volume: 88

    Topics: Alcoholics; Alcoholism; Methylphenidate; Reserpine

1961
THE SYNDROME OF NARCOLEPSY AND DIABETOGENIC (FUNCTIONAL) HYPERINSULINISM. OBSERVATIONS ON 190 PATIENTS, WITH EMPHASIS UPON ITS RELATIONSHIP TO OBESITY, DIABETES MELLITUS AND CEREBRAL DYSRHYTHMIAS.
    The Journal of the Florida Medical Association. Florida Medical Association, 1963, Volume: 50

    Topics: Adolescent; Alcoholism; Arrhythmias, Cardiac; Brain; Diabetes Mellitus; Diet; Diet, Reducing; Electr

1963
THE SYNDROME OF NARCOLEPSY AND DIABETOGENIC ("FUNCTIONAL") HYPERINSULINISM, WITH SPECIAL REFERENCE TO OBESITY, DIABETES, IDIOPATHIC EDEMA, CEREBRAL DYSRHYTHMIAS AND MULTIPLE SCLEROSIS (200 PATIENTS).
    Journal of the American Geriatrics Society, 1964, Volume: 12

    Topics: Alcoholism; Arrhythmias, Cardiac; Cerebrovascular Disorders; Diabetes Mellitus; Drug Therapy; Edema;

1964
Acute alcoholic intoxication: use of methylphenidylate.
    American practitioner and digest of treatment, 1960, Volume: 11

    Topics: Alcoholic Intoxication; Alcoholism; Humans; Methylphenidate

1960
Characteristics of methylphenidate misuse in a university student sample.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2005, Volume: 50, Issue:8

    Topics: Adolescent; Adult; Alcoholism; Attention; Central Nervous System Stimulants; Comorbidity; Cross-Sect

2005
[Diagnosis and treatment of the attention-deficit/hyperactivity syndrome (ADHS) in adults with drug addiction in in-patient and out-patient setting].
    Psychiatrische Praxis, 2006, Volume: 33, Issue:5

    Topics: Adult; Alcoholism; Ambulatory Care; Attention Deficit Disorder with Hyperactivity; Borderline Person

2006
Misuse of methamphetamine and prescription stimulants among youths and young adults in the community.
    Drug and alcohol dependence, 2007, Jul-10, Volume: 89, Issue:2-3

    Topics: Adolescent; Adult; Alcoholism; Amphetamine-Related Disorders; Central Nervous System Stimulants; Com

2007
The nonmedical use of prescription ADHD medications: results from a national Internet panel.
    Substance abuse treatment, prevention, and policy, 2007, Oct-31, Volume: 2

    Topics: Adolescent; Adult; Alcoholism; Amphetamine-Related Disorders; Appetite Depressants; Attention Defici

2007
A case of disulfiram-methylphenidate interaction: implications for treatment.
    The American journal of psychiatry, 2007, Volume: 164, Issue:11

    Topics: Adult; Alcoholism; Attention Deficit Disorder with Hyperactivity; Disulfiram; Dopamine beta-Hydroxyl

2007
Profound decreases in dopamine release in striatum in detoxified alcoholics: possible orbitofrontal involvement.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Nov-14, Volume: 27, Issue:46

    Topics: Adult; Alcohol-Induced Disorders, Nervous System; Alcoholism; Brain Chemistry; Central Nervous Syste

2007
Use of stimulants for alcoholic patients with attention deficit disorder.
    The American journal of psychiatry, 1983, Volume: 140, Issue:9

    Topics: Adult; Alcoholism; Attention Deficit Disorder with Hyperactivity; Humans; Male; Methylphenidate

1983
Decreases in dopamine receptors but not in dopamine transporters in alcoholics.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:9

    Topics: Adult; Alcohol Drinking; Alcoholism; Brain; Carbon Radioisotopes; Carrier Proteins; Corpus Striatum;

1996
[Attention deficit hyperactivity disorder, facilitating alcohol and drug abuse in an adult].
    Harefuah, 1997, May-01, Volume: 132, Issue:9

    Topics: Adult; Alcoholism; Attention Deficit Disorder with Hyperactivity; Cannabis; Central Nervous System S

1997
Methylphenidate treatment of neuropsychiatric symptoms of central and extrapontine myelinolysis.
    Journal of studies on alcohol, 2000, Volume: 61, Issue:5

    Topics: Alcoholism; Central Nervous System Stimulants; Chronic Disease; Corpus Striatum; Humans; Magnetic Re

2000
Seven cases of somnambulism induced by drugs.
    The American journal of psychiatry, 1979, Volume: 136, Issue:7

    Topics: Adult; Alcoholism; Amitriptyline; Chlorprothixene; Depression; Drug Therapy, Combination; Ethchlorvy

1979
Intravenous methylphenidate as a diagnostic and psychotherapeutic instrument in adult psychiatry.
    Canadian Psychiatric Association journal, 1976, Volume: 21, Issue:7

    Topics: Abreaction; Adult; Alcoholism; Antisocial Personality Disorder; Anxiety; Defense Mechanisms; Depress

1976
Intranasal abuse of prescribed methylphenidate by an alcohol and drug abusing adolescent with ADHD.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:5

    Topics: Administration, Intranasal; Adolescent; Alcoholism; Arousal; Attention Deficit Disorder with Hyperac

1991
Characteristics of alcoholics volunteering for lysergide treatment.
    Quarterly journal of studies on alcohol, 1970, Volume: 31, Issue:2

    Topics: Adult; Aged; Alcoholism; Attitude to Health; Bender-Gestalt Test; Chlordiazepoxide; Educational Stat

1970