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methylphenidate and Affective Disorders

methylphenidate has been researched along with Affective Disorders in 14 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
"Methylphenidate hydrochloride (Ritalin) has been used to treat both depression and apathy."9.05Methylphenidate in depression and states of apathy. ( Moore, DP, 1981)
" We sought to prospectively study the effects of levodopa (LD) and/or methylphenidate (MPH) in combination with physiotherapy on mood and cognition following stroke in human subjects."6.76Effect of methylphenidate and/or levodopa combined with physiotherapy on mood and cognition after stroke: a randomized, double-blind, placebo-controlled trial. ( Delbari, A; Lokk, J; Salman-Roghani, R, 2011)
"Methylphenidate hydrochloride (Ritalin) has been used to treat both depression and apathy."5.05Methylphenidate in depression and states of apathy. ( Moore, DP, 1981)
" We sought to prospectively study the effects of levodopa (LD) and/or methylphenidate (MPH) in combination with physiotherapy on mood and cognition following stroke in human subjects."2.76Effect of methylphenidate and/or levodopa combined with physiotherapy on mood and cognition after stroke: a randomized, double-blind, placebo-controlled trial. ( Delbari, A; Lokk, J; Salman-Roghani, R, 2011)
"The diagnosis of attention deficit disorder, residual type, should be considered in patients with prominent complaints of impulsivity, restlessness, emotional lability, and hot temper who do not suffer from schizophrenia or major mood disorder and do not have symptoms of schizotypal or borderline personality disorders."2.66A controlled study of methylphenidate in the treatment of attention deficit disorder, residual type, in adults. ( Reimherr, FW; Ward, M; Wender, PH; Wood, D, 1985)
"Increased research focusing on the eating disorders has put the clinician on firmer ground when choosing appropriate psychopharmacologic treatments."2.37Pharmacologic treatment of eating disorders. ( Gwirtsman, H; Jimerson, DC; Kaye, W; Weintraub, M, 1984)
"The most common comorbidities were substance use disorders (39."1.43Psychiatric Comorbidity at the Time of Diagnosis in Adults With ADHD: The CAT Study. ( Balanzá-Martínez, V; García-García, P; Piñeiro-Dieguez, B; Soler-López, B, 2016)
"Methylphenidate (MPH) is a neural stimulant with unclear neurochemical and behavioral effects."1.43The neuroprotective effect of lithium against high dose methylphenidate: Possible role of BDNF. ( Asadi, M; Motaghinejad, M; Motevalian, M; Seyedjavadein, Z, 2016)
"Patients with unipolar depression were studied in a drug-free baseline state following short-term administration of methylphenidate and in a euthymic state in long-term follow-up."1.27Positron emission tomographic study of affective disorders: problems and strategies. ( Baxter, L; Gerner, R; Mazziotta, JC; Phelps, ME, 1984)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's1 (7.14)18.2507
2000's2 (14.29)29.6817
2010's6 (42.86)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Friedrich, B1
Bridler, R1
Moukhtarian, TR1
Cooper, RE1
Vassos, E1
Moran, P1
Asherson, P1
Spada, MM1
Piñeiro-Dieguez, B1
Balanzá-Martínez, V1
García-García, P1
Soler-López, B1
Motaghinejad, M1
Seyedjavadein, Z1
Motevalian, M1
Asadi, M1
Spiegel, DR1
Kim, J1
Greene, K1
Conner, C1
Zamfir, D1
Auyeung, SF1
Long, Q1
Royster, EB1
Murthy, S1
McNutt, MD1
Lawson, D1
Miller, A1
Manatunga, A1
Musselman, DL1
Marcus, SC1
Durkin, M1
Delbari, A1
Salman-Roghani, R1
Lokk, J1
Gwirtsman, H1
Kaye, W1
Weintraub, M1
Jimerson, DC1
Phelps, ME1
Mazziotta, JC1
Baxter, L1
Gerner, R1
Moore, DP1
Suffin, SC1
Emory, WH1
Wender, PH1
Reimherr, FW1
Wood, D1
Ward, M1

Reviews

3 reviews available for methylphenidate and Affective Disorders

ArticleYear
Effects of stimulants and atomoxetine on emotional lability in adults: A systematic review and meta-analysis.
    European psychiatry : the journal of the Association of European Psychiatrists, 2017, Volume: 44

    Topics: Adult; Affective Symptoms; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity;

2017
An overview of problematic internet use.
    Addictive behaviors, 2014, Volume: 39, Issue:1

    Topics: Antidepressive Agents, Second-Generation; Behavior, Addictive; Central Nervous System Stimulants; Ci

2014
Pharmacologic treatment of eating disorders.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Anorexia Nervosa; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Central

1984

Trials

3 trials available for methylphenidate and Affective Disorders

ArticleYear
Effect of methylphenidate and/or levodopa combined with physiotherapy on mood and cognition after stroke: a randomized, double-blind, placebo-controlled trial.
    European neurology, 2011, Volume: 66, Issue:1

    Topics: Aged; Analysis of Variance; Antiparkinson Agents; Central Nervous System Stimulants; Cognition Disor

2011
Methylphenidate in depression and states of apathy.
    Southern medical journal, 1981, Volume: 74, Issue:3

    Topics: Clinical Trials as Topic; Depression; Double-Blind Method; Humans; Methylphenidate; Mood Disorders

1981
A controlled study of methylphenidate in the treatment of attention deficit disorder, residual type, in adults.
    The American journal of psychiatry, 1985, Volume: 142, Issue:5

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; Clinical Tria

1985

Other Studies

8 other studies available for methylphenidate and Affective Disorders

ArticleYear
    Praxis, 2020, Volume: 109, Issue:16

    Topics: Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Humans; Mania; Methylphenidate; Moo

2020
Psychiatric Comorbidity at the Time of Diagnosis in Adults With ADHD: The CAT Study.
    Journal of attention disorders, 2016, Volume: 20, Issue:12

    Topics: Adult; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Comorbidity; Cross-Sectiona

2016
The neuroprotective effect of lithium against high dose methylphenidate: Possible role of BDNF.
    Neurotoxicology, 2016, Volume: 56

    Topics: Animals; Brain-Derived Neurotrophic Factor; Central Nervous System Stimulants; Cytokines; Disease Mo

2016
Apathy due to cerebrovascular accidents successfully treated with methylphenidate: a case series.
    The Journal of neuropsychiatry and clinical neurosciences, 2009,Spring, Volume: 21, Issue:2

    Topics: Aged; Depression; Humans; Male; Methylphenidate; Middle Aged; Mood Disorders; Motivation; Stroke; Tr

2009
Sequential multiple-assignment randomized trial design of neurobehavioral treatment for patients with metastatic malignant melanoma undergoing high-dose interferon-alpha therapy.
    Clinical trials (London, England), 2009, Volume: 6, Issue:5

    Topics: Behavioral Symptoms; Citalopram; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Doubl

2009
Stimulant adherence and academic performance in urban youth with attention-deficit/hyperactivity disorder.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2011, Volume: 50, Issue:5

    Topics: Achievement; Adolescent; Amphetamine; Anxiety Disorders; Attention Deficit and Disruptive Behavior D

2011
Positron emission tomographic study of affective disorders: problems and strategies.
    Annals of neurology, 1984, Volume: 15 Suppl

    Topics: Bipolar Disorder; Depressive Disorder; Female; Glucose; Humans; Lithium; Male; Methylphenidate; Mood

1984
Neurometric subgroups in attentional and affective disorders and their association with pharmacotherapeutic outcome.
    Clinical EEG (electroencephalography), 1995, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Antidepressive Agents; Attention Deficit Disorder with Hyperacti

1995
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