Page last updated: 2024-10-31

methylphenidate and Addiction, Opioid

methylphenidate has been researched along with Addiction, Opioid in 12 studies

Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
" At each daily visit, signs and symptoms were assessed, and medications and dosing instructions were given for the following 24 hours."1.37A nonopioid procedure for outpatient opioid detoxification. ( Baier, AR; Coons, EE; Fingesten, A; Ockert, DM; Volpicelli, JR, 2011)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's1 (8.33)29.6817
2010's4 (33.33)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Soeiro, T1
Frauger, É1
Pradel, V1
Micallef, J1
Vohra, V1
King, A1
Daviskiba, S1
Reed, B1
Rockhill, S1
Kern, P1
Dean, D1
Rolland, B1
Jordan, CJ1
Cao, J1
Newman, AH1
Xi, ZX1
Dahlman, D1
Håkansson, A1
Björkman, P1
Blomé, MA1
Kral, AH1
Fleary, SA1
Heffer, RW1
McKyer, EL1
Ockert, DM1
Volpicelli, JR1
Baier, AR1
Coons, EE1
Fingesten, A1
Levin, FR1
Evans, SM1
Brooks, DJ1
Kalbag, AS1
Garawi, F1
Nunes, EV1
Haglund, RM1
Howerton, LL1
Volkow, ND1
Fowler, JS1
Hitzemann, R1
Wang, GJ1
van Dyck, CH1
McMahon, TJ1
Rosen, MI1
O'Malley, SS1
O'Connor, PG1
Lin, CH1
Pearsall, HR1
Woods, SW1
Kosten, TR1
Elangovan, N1
Barbato, M1
Cooper, T1
Winsberg, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Adult ADHD in Methadone Patients[NCT00061087]Phase 2/Phase 3115 participants (Actual)Interventional1998-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for methylphenidate and Addiction, Opioid

ArticleYear
Progress in agonist therapy for substance use disorders: Lessons learned from methadone and buprenorphine.
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: Analgesics, Opioid; Buprenorphine; Central Nervous System Stimulants; Cocaine-Related Disorders; Dex

2019

Trials

3 trials available for methylphenidate and Addiction, Opioid

ArticleYear
Treatment of methadone-maintained patients with adult ADHD: double-blind comparison of methylphenidate, bupropion and placebo.
    Drug and alcohol dependence, 2006, Feb-01, Volume: 81, Issue:2

    Topics: Adult; Algorithms; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Attention Deficit D

2006
Sustained-release methylphenidate for cognitive impairment in HIV-1-infected drug abusers: a pilot study.
    The Journal of neuropsychiatry and clinical neurosciences, 1997,Winter, Volume: 9, Issue:1

    Topics: Adult; Attention; Central Nervous System Stimulants; Cognition Disorders; Delayed-Action Preparation

1997
Neurohormonal and behavioral response to methylphenidate in cocaine abstinence.
    Psychiatry research, 1996, Nov-15, Volume: 65, Issue:2

    Topics: Adult; Arousal; Central Nervous System Stimulants; Cocaine; Dopamine; Drug Administration Schedule;

1996

Other Studies

8 other studies available for methylphenidate and Addiction, Opioid

ArticleYear
Doctor shopping for methylphenidate as a proxy for misuse and potential abuse in the 67 million inhabitants in France.
    Fundamental & clinical pharmacology, 2021, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Cross-Sectional Studies; Female; France; Humans; Male; Methylphenidate; Middle Ag

2021
Stimulant storm - state health department psychostimulant age-adjusted mortality rate correlates with psychostimulant-based Michigan Poison Center case exposures over time.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:8

    Topics: Adult; Amphetamine; Central Nervous System Stimulants; Dextroamphetamine; Drug Overdose; Female; Hum

2021
Doctor shopping for methylphenidate as a proxy for misuse and potential abuse in the 67 million inhabitants in France.
    Fundamental & clinical pharmacology, 2021, Volume: 35, Issue:4

    Topics: France; Humans; Methylphenidate; Opioid-Related Disorders; Physicians; Prescription Drug Misuse

2021
Correlates of Skin and Soft Tissue Infections in Injection Drug Users in a Syringe-Exchange Program in Malmö, Sweden.
    Substance use & misuse, 2015, Volume: 50, Issue:12

    Topics: Adult; Amphetamine-Related Disorders; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Drug

2015
Dispositional, ecological and biological influences on adolescent tranquilizer, Ritalin, and narcotics misuse.
    Journal of adolescence, 2011, Volume: 34, Issue:4

    Topics: Adolescent; Child; Dopamine Uptake Inhibitors; Female; Humans; Male; Methylphenidate; Opioid-Related

2011
A nonopioid procedure for outpatient opioid detoxification.
    Journal of addiction medicine, 2011, Volume: 5, Issue:2

    Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adult; Benzhydryl Compounds; Central Nervous Syste

2011
Ritalin: consequences of abuse in a clinical population.
    The International journal of the addictions, 1982, Volume: 17, Issue:2

    Topics: Adult; Female; Humans; Injections, Intravenous; Male; Methadone; Methylphenidate; Opioid-Related Dis

1982
Neurochemical mechanisms underlying responses to psychostimulants.
    NIDA research monograph, 1996, Volume: 159

    Topics: Animals; Behavior; Brain; Brain Chemistry; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake

1996