methylphenidate has been researched along with Acute Post-Traumatic Stress Disorder in 5 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our patient presented to the emergency department with priapism, approximately 3 months after beginning a pharmacologic regimen of escitalopram, prazosin, trazodone, and methylphenidate for PTSD." | 3.85 | Recurrent Priapism in a Military Veteran Receiving Treatment for PTSD. ( George, AK; Mann, RA, 2017) |
| "The defining symptoms of PTSD include re-experiencing, avoidance and hyperarousal." | 1.40 | Methylphenidate and desipramine combined treatment improves PTSD symptomatology in a rat model. ( Aga-Mizrachi, S; Avital, A; Balan, A; Cymerblit-Sabba, A; Deshe, R; Gorodetsky, N; Grinstein, D; Gurman, O; Heinrich, N; Miller, L; Shwam, G; Tzezana, O; Zubedat, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mann, RA | 1 |
| George, AK | 1 |
| Aga-Mizrachi, S | 1 |
| Cymerblit-Sabba, A | 1 |
| Gurman, O | 1 |
| Balan, A | 1 |
| Shwam, G | 1 |
| Deshe, R | 1 |
| Miller, L | 1 |
| Gorodetsky, N | 1 |
| Heinrich, N | 1 |
| Tzezana, O | 1 |
| Zubedat, S | 1 |
| Grinstein, D | 1 |
| Avital, A | 1 |
| McAllister, TW | 1 |
| Zafonte, R | 1 |
| Jain, S | 1 |
| Flashman, LA | 1 |
| George, MS | 1 |
| Grant, GA | 1 |
| He, F | 1 |
| Lohr, JB | 1 |
| Andaluz, N | 1 |
| Summerall, L | 1 |
| Paulus, MP | 1 |
| Raman, R | 1 |
| Stein, MB | 1 |
| Borenstein, M | 1 |
| Higgins, JP | 1 |
| Hedges, LV | 1 |
| Rothstein, HR | 1 |
| Ritov, G | 1 |
| Richter-Levin, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Relation Between Attentional, Sensory and Emotional Dysregulation in Adults With Posttraumatic Stress Disorder: a Double-blind, Placebo-controlled Randomized Controlled Trial of the Combined Treatment With Reboxetine and Methylphenidate[NCT05133804] | Phase 2 | 53 participants (Anticipated) | Interventional | 2022-06-01 | Recruiting | ||
| A Randomized Placebo-controlled Trial of Methylphenidate in Veterans With a Diagnosis of Post Traumatic Stress Disorder and Recent Cerebral Stroke.[NCT04885257] | Phase 2 | 60 participants (Anticipated) | Interventional | 2022-01-14 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for methylphenidate and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Randomized Placebo-Controlled Trial of Methylphenidate or Galantamine for Persistent Emotional and Cognitive Symptoms Associated with PTSD and/or Traumatic Brain Injury.
Topics: Adult; Affective Symptoms; Brain Injuries, Traumatic; Cognition Disorders; Double-Blind Method; Fema | 2016 |
Randomized Placebo-Controlled Trial of Methylphenidate or Galantamine for Persistent Emotional and Cognitive Symptoms Associated with PTSD and/or Traumatic Brain Injury.
Topics: Adult; Affective Symptoms; Brain Injuries, Traumatic; Cognition Disorders; Double-Blind Method; Fema | 2016 |
Randomized Placebo-Controlled Trial of Methylphenidate or Galantamine for Persistent Emotional and Cognitive Symptoms Associated with PTSD and/or Traumatic Brain Injury.
Topics: Adult; Affective Symptoms; Brain Injuries, Traumatic; Cognition Disorders; Double-Blind Method; Fema | 2016 |
Randomized Placebo-Controlled Trial of Methylphenidate or Galantamine for Persistent Emotional and Cognitive Symptoms Associated with PTSD and/or Traumatic Brain Injury.
Topics: Adult; Affective Symptoms; Brain Injuries, Traumatic; Cognition Disorders; Double-Blind Method; Fema | 2016 |
4 other studies available for methylphenidate and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Recurrent Priapism in a Military Veteran Receiving Treatment for PTSD.
Topics: Adult; Citalopram; Humans; Male; Methylphenidate; Prazosin; Priapism; Psychotropic Drugs; Stress Dis | 2017 |
Methylphenidate and desipramine combined treatment improves PTSD symptomatology in a rat model.
Topics: Animals; Antidepressive Agents, Tricyclic; Central Nervous System Stimulants; Desipramine; Disease M | 2014 |
Basics of meta-analysis: I
Topics: Algorithms; Attention Deficit Disorder with Hyperactivity; Attitude; Cognition; Effect Modifier, Epi | 2017 |
Pre-trauma Methylphenidate in rats reduces PTSD-like reactions one month later.
Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Classical; Fear; Learnin | 2017 |