Page last updated: 2024-08-21

methylnitrosourea and Prostatic Neoplasms

methylnitrosourea has been researched along with Prostatic Neoplasms in 73 studies

Research

Studies (73)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (8.22)	18.7374
1990's	27 (36.99)	18.2507
2000's	20 (27.40)	29.6817
2010's	17 (23.29)	24.3611
2020's	3 (4.11)	2.80

Authors

Authors	Studies
Acevedo, N; Bosland, MC; Prins, G; Schlicht, MJ; Soto, AM	1
Colaco, B; DA Costa, RMG; Fardilha, M; Faustino-Rocha, AI; Ferreira, R; Moreira-Goncalves, D; Nascimento-Goncalves, E; Neuparth, MJ; Oliveira, PA; Pires, MJ; Seixas, F	1
Abedi, S; Doosti, A; Jami, MS	1
Saedmocheshi, S; Saghebjoo, M; Sheikholeslami-Vatani, D; Vahabzadeh, Z	1
de Campos, SGP; Góes, RM; Gonçalves, BF; Scarano, WR; Taboga, SR; Vilamaior, PSL	1
Gonçalves, BF; Maldonado, CA; Quintar, AA; Taboga, SR	1
Amorim, RL; de Campos, SG; Falleiros, LR; Góes, RM; Gonçalves, BF; Scarano, WR; Taboga, SR; Zanetoni, C	1
Chen, MH; Chen, YL; Chiu, HW; Fang, WH; Hung, CM; Wang, YJ; Wu, MD; Wu, MJ; Yuan, GF	1
Ngalame, NN; Orihuela, RG; Person, RJ; Tokar, EJ; Waalkes, MP; Xu, Y	1
Do, SH; Lee, HR; Lim, HK	1
Bosland, MC	3
Lind, J; Sinha, AA; Wilson, MJ	1
Ding, H; Feng, G; Li, J; Lin, D; Liu, T; Luo, F; Ma, P; Wang, J; Xu, Y; Yang, K	1
Chadha, VD; Dhawan, DK; Jan, G; Passi, ND	1
Boyadjieva, NI; Chen, CP; Clement, EM; Kuhn, P; Marano, J; Ortigüela, M; Reuhl, K; Sarkar, DK	1
Sailes, VT; Suckow, MA; Wolter, WR	1
Gopalakrishna, R; Gottlieb, SN; Gundimeda, U; Roth, BI; Schiffman, JE	1
Campos, SG; Góes, RM; Gonçalves, BF; Scarano, WR; Taboga, SR; Vilamaior, PS; Zanetoni, C	1
Bosland, MC; Johnson, WD; Lubet, RA; McCormick, DL; Rao, KV; Steele, VE	1
Arunakaran, J; Arunkumar, R; Banudevi, S; Elumalai, P; Gunadharini, DN; Senthilkumar, K; Sharmila, G	1
Bevan, CL; Keun, HC; Teahan, O; Waxman, J	1
Arunakaran, J; Arunkumar, R; Banudevi, S; Elumalai, P; Senthilkumar, K; Sharmila, G	1
Bespalov, VG; Chepik, OF; Murazov, IaG; Panchenko, AV	1
Eltoum, IE; Lamartiniere, CA; Wang, J	1
Boileau, TW; Clinton, SK; Erdman, JW; Liao, Z	1
Chan, FL; Chen, ZY; Cheung, SY; Choi, HL; Huang, Y; James, AE	1
Bosland, MC; Condon, MS; Narayanan, BA; Narayanan, NK; Reddy, BS	1
Boileau, TW; Clinton, SK; Erdman, JW; Kim, S; Lemeshow, S; Liao, Z	1
Krämer, K; Limpens, J; Obermüller-Jevic, UC; Pallapies, D; Schröder, FH; van Weerden, WM	1
Boileau, TW; Clinton, SK; Erdman, JW; Liao, Z; Wang, S	1
Pollard, M; Suckow, MA; Wolter, W	1
Pollard, M; Suckow, MA	1
Bosland, MC; Johnson, WD; Lubet, RA; McCormick, DL; Steele, VE	1
Bosland, MC; Haryu, TM; Johnson, WD; Lubet, RA; McCormick, DL; Steele, VE	1
Bosland, MC; Horton, L; Narayanan, BA; Narayanan, NK; Nargi, D; Randolph, C; Reddy, BS	1
Bisson, JF; Guardia-Llorens, MA; Hidalgo, S; Messaoudi, M; Rozan, P	1
Bosland, MC; Kroes, R; Prinsen, MK	1
Cohen, MB; Heidger, PM; Lubaroff, DM	1
Anver, MR; Anzano, MA; Brown, CC; Driver, CL; Green, DM; Logsdon, DL; Lucia, MS; Peer, CW; Shrader, MW; Slayter, MV	1
Luckert, PH; Pollard, M; Scheu, J	1
Anzano, MA; Danielpour, D; Kadomatsu, K; Smith, JM; Sporn, MB	1
Luckert, PH; Pollard, M	5
Anzano, MA; Kadomatsu, K; Slayter, MV; Smith, JM; Sporn, MB	1
Adamson, AS; Amirkhosravi, M; Francis, JL; Luckert, P; Pollard, M; Snell, ME	1
Anzano, MA; Kadomatsu, K; Slayter, MV; Smith, JM; Sporn, MB; Winokur, TS	1
Austin, GE; Collins, DC; Dillehay, DL; Fallon, MT; Schleicher, RL; Zhang, M; Zheng, M	1
Rehm, S; Tamano, S; Waalkes, MP; Ward, JM	1
Bosland, MC; Dooley, L; Kelloff, GJ; Lubet, RA; McCormick, DL; Rao, KV; Steele, VE	1
Bosland, MC; Kelloff, GJ; Lubet, RA; McCormick, DL; Rao, KV; Steele, VE	1
Bosland, MC; Johnson, WD; Kelloff, GJ; Lubet, RA; McCormick, DL; Rao, KV; Steele, VE	1
Bosland, MC; Condon, MS; Crivello, JF; Horton, L; Kaplan, LA	1
Pollard, M; Sun, L; Wolter, WR	1
Cui, L; Futakuchi, M; Imaida, K; Kato, K; Shirai, T; Takahashi, S; Tamano, S	1
Bello-DeOcampo, D; Bice, G; DeMendonca-Calaca, W; Kleinman, HK; Quader, ST; Storto, PD; Webber, MM; Williams, DE	1
Bello-DeOcampo, D; Kleinman, HK; Quader, ST; Webber, MM; Williams, DE	1
Pollard, M	1
Hasegawa, R; Imaida, K; Mori, T; Shirai, T; Tamano, S; Yamamoto, A	1
Ito, N; Shirari, T; Takahashi, S; Tamano, S	1
Bosland, MC; Fiala, E; Kroes, R; Prinsen, MK; Rivenson, A; Silverman, J; Weisburger, JH; Williams, GM	1
Armstrong, B; Bosland, MC; Bruyntjes, JP; Leav, I; Sukumar, S	1
Iwasaki, S; Masui, T; Shirai, T; Tamano, S; Yamamoto, A	1
Bosland, MC; Dirksen, TJ; Prinsen, MK; Spit, BJ	1
Bosland, MC; Prinsen, MK	1
Akaza, H; Aso, Y; Hosaka, Y; Shirai, T; Tomita, K	1
Ikawa, E; Ito, N; Shirai, T; Tagawa, Y	1
Aso, Y; Kakizoe, T; Kishi, K; Ohtani, M; Sato, S; Takai, K; Tobisu, K	1
Luckert, PH; Pollard, M; Snyder, DL	1

Reviews

6 review(s) available for methylnitrosourea and Prostatic Neoplasms

Article	Year
Appraising Animal Models of Prostate Cancer for Translational Research: Future Directions. Anticancer research, 2023, Volume: 43, Issue:1 Topics: Animals; Disease Models, Animal; Humans; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Testosterone; Translational Research, Biomedical	2023
Dietary prevention of hormone refractory prostate cancer in Lobund-Wistar rats: a review of studies in a relevant animal model. Comparative medicine, 2006, Volume: 56, Issue:6 Topics: Animals; Diet; Disease Models, Animal; Drug Resistance, Neoplasm; Isoflavones; Male; Methylnitrosourea; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Rats, Wistar; Soybean Proteins; Testosterone	2006
Use of animal models in defining efficacy of chemoprevention agents against prostate cancer. European urology, 1999, Volume: 35, Issue:5-6 Topics: Animals; Antineoplastic Agents; Carcinoma in Situ; Disease Models, Animal; Humans; Male; Methylnitrosourea; Mice; Mice, Transgenic; Neoplasms, Experimental; Prostatic Neoplasms; Rats; Sensitivity and Specificity; Treatment Outcome	1999
Experimental prostate carcinogenesis - rodent models. Mutation research, 2000, Volume: 462, Issue:2-3 Topics: Aminobiphenyl Compounds; Animals; Carcinogens; Disease Models, Animal; Imidazoles; Male; Methylnitrosourea; Mice; Mice, Transgenic; Nitrosamines; Prostatic Neoplasms; Rats; Rats, Inbred F344; Rats, Inbred Strains; Rats, Wistar	2000
The Lobund-Wistar rat model of prostate cancer. Journal of cellular biochemistry. Supplement, 1992, Volume: 16H Topics: Adenocarcinoma; Animals; Disease Models, Animal; Male; Methylnitrosourea; Precancerous Conditions; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone	1992
Animal models for the study of prostate carcinogenesis. Journal of cellular biochemistry. Supplement, 1992, Volume: 16H Topics: Animals; Disease Models, Animal; Humans; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Testosterone	1992

Other Studies

67 other study(ies) available for methylnitrosourea and Prostatic Neoplasms

Article	Year
Effects of perinatal exposure to bisphenol A on induction of prostate cancer in Sprague Dawley rats by MNU and testosterone. Toxicology, 2023, 01-15, Volume: 484 Topics: Animals; Benzhydryl Compounds; Carcinogenesis; Carcinoma; Estradiol; Humans; Infant, Newborn; Male; Methylnitrosourea; Pregnancy; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Testosterone	2023
Evaluation of the preventive and therapeutic effects of a recombinant vector co-expressing prostate-specific stem cell antigen and Clostridium perfringens enterotoxin on prostate cancer in rats. Biotechnology progress, 2020, Volume: 36, Issue:2 Topics: Animals; Chitosan; Enterotoxins; Injections, Intramuscular; Male; Methylnitrosourea; Nanoparticles; Prostate-Specific Antigen; Prostatic Neoplasms; Rats; Rats, Wistar; Recombinant Proteins; Testosterone	2020
Aerobic Training and Green Tea Extract Protect against N-methyl-N-nitrosourea-induced Prostate Cancer. Medicine and science in sports and exercise, 2019, Volume: 51, Issue:11 Topics: Animals; Anticarcinogenic Agents; Body Weight; Cyclooxygenase 2; Male; Methylnitrosourea; NF-kappa B; Organ Size; Physical Conditioning, Animal; Plant Extracts; Prostate; Prostatic Neoplasms; Rats, Wistar; Tea; Tumor Suppressor Protein p53	2019
Dual action of high estradiol doses on MNU-induced prostate neoplasms in a rodent model with high serum testosterone: Protective effect and emergence of unstable epithelial microenvironment. The Prostate, 2017, Volume: 77, Issue:9 Topics: Androgens; Animals; Carcinogenesis; Carcinogens; Disease Progression; DNA Damage; Epithelial Cells; Estradiol; Male; Methylnitrosourea; Prostate; Prostatic Neoplasms; Protective Factors; Rats	2017
The mongolian gerbil (Meriones unguiculatus) as a model for inflammation-promoted prostate carcinogenesis. Cell biology international, 2017, Volume: 41, Issue:11 Topics: Animals; Carcinogenesis; Disease Models, Animal; Gerbillinae; Inflammation; Male; Methylnitrosourea; Prostatic Neoplasms	2017
A new proposed rodent model of chemically induced prostate carcinogenesis: distinct time-course prostate cancer progression in the dorsolateral and ventral lobes. The Prostate, 2013, Volume: 73, Issue:11 Topics: Alkylating Agents; Animals; Disease Models, Animal; Disease Progression; Gerbillinae; Male; Methylnitrosourea; Prostate; Prostatic Neoplasms; Testosterone; Time Factors	2013
Preventive effects of Monascus on androgen-related diseases: androgenetic alopecia, benign prostatic hyperplasia, and prostate cancer. Journal of agricultural and food chemistry, 2013, May-08, Volume: 61, Issue:18 Topics: Administration, Oral; Aging; Alopecia; Animals; Dihydrotestosterone; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Monascus; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Testosterone	2013
Recruitment of normal stem cells to an oncogenic phenotype by noncontiguous carcinogen-transformed epithelia depends on the transforming carcinogen. Environmental health perspectives, 2013, Volume: 121, Issue:8 Topics: Animals; Blotting, Western; Cadmium; Carcinogens; Carcinoma; Cell Line, Tumor; Cell Transformation, Neoplastic; Environmental Pollutants; Epithelial Cells; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinases; Methylnitrosourea; Mice; Mice, Nude; Neoplastic Stem Cells; Polymerase Chain Reaction; Prostatic Neoplasms; Transforming Growth Factor alpha	2013
Stimulation of cannabinoid receptors by using Rubus coreanus extracts to control osteoporosis in aged male rats. The aging male : the official journal of the International Society for the Study of the Aging Male, 2015, Volume: 18, Issue:2 Topics: Aging; Animals; Disease Models, Animal; Male; Methylnitrosourea; Osteoporosis; Phytotherapy; Plant Extracts; Prostate; Prostatic Neoplasms; Rats; Receptors, Cannabinoid; Rubus	2015
Testosterone treatment is a potent tumor promoter for the rat prostate. Endocrinology, 2014, Volume: 155, Issue:12 Topics: Androgens; Animals; Carcinoma; Dose-Response Relationship, Drug; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Testosterone	2014
Induction of a heparin-stimulated serine proteinase in sex accessory gland tumors of the Lobund-Wistar rat. Experimental and molecular pathology, 2015, Volume: 99, Issue:1 Topics: Animals; Heparin; Male; Methylnitrosourea; Prostate; Prostatic Neoplasms; Rats; Rats, Wistar; Seminal Vesicles; Serine Proteases; Sulfones; Testosterone Propionate	2015
Bone marrow mesenchymal stem cells participate in prostate carcinogenesis and promote growth of prostate cancer by cell fusion in vivo. Oncotarget, 2016, May-24, Volume: 7, Issue:21 Topics: Animals; Antigens, Ly; Carcinogenesis; Cell Fusion; Disease Progression; Leukocyte Common Antigens; Male; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, SCID; Mice, Transgenic; Neoplasms, Experimental; Prostate; Prostatic Neoplasms; Tumor Microenvironment	2016
Cancer Targeting Potential of Cancer biotherapy & radiopharmaceuticals, 2017, Volume: 32, Issue:2 Topics: Acid Phosphatase; Animals; Carcinogenesis; Carcinogens; Disease Models, Animal; Electrophoresis; Finasteride; Hydrogen-Ion Concentration; Kinetics; Male; Methylnitrosourea; Prostate; Prostatic Neoplasms; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Technetium; Time Factors; Tissue Distribution	2017
Cyclic adenosine monophosphate differentiated beta-endorphin neurons promote immune function and prevent prostate cancer growth. Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26 Topics: Animals; beta-Endorphin; Cell Death; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclic AMP; Female; Hypothalamus; Interferon-gamma; Killer Cells, Natural; Male; Methylnitrosourea; Neurons; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Stem Cells; Testosterone; Tumor Necrosis Factor-alpha	2008
Inhibition of prostate cancer metastasis by administration of a tissue vaccine. Clinical & experimental metastasis, 2008, Volume: 25, Issue:8 Topics: Adenocarcinoma; Animals; Cancer Vaccines; Cytokines; Glutaral; Immunotherapy; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Wistar; Spleen; Survival Rate; Testosterone; Tumor Cells, Cultured; Vaccination; Xenograft Model Antitumor Assays	2008
Negation of the cancer-preventive actions of selenium by over-expression of protein kinase Cepsilon and selenoprotein thioredoxin reductase. Carcinogenesis, 2009, Volume: 30, Issue:9 Topics: Anticarcinogenic Agents; Cell Line, Tumor; Humans; Indoles; Male; Maleimides; Methylnitrosourea; Neoplasm Invasiveness; Organoselenium Compounds; Prostatic Neoplasms; Protein Kinase C-epsilon; Thioredoxin-Disulfide Reductase	2009
Prostate carcinogenesis induced by N-methyl-N-nitrosourea (mnu) in gerbils: histopathological diagnosis and potential invasiveness mediated by extracellular matrix components. Experimental and molecular pathology, 2010, Volume: 88, Issue:1 Topics: Adenocarcinoma; Alkylating Agents; Animals; Biomarkers, Tumor; Cell Proliferation; Collagen; Disease Models, Animal; Drug Therapy, Combination; Epithelial Cells; Extracellular Matrix; Gerbillinae; Inflammation; Male; Methylnitrosourea; Neoplasm Invasiveness; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Racemases and Epimerases; Reticulin; Testosterone; Time Factors	2010
Null activity of selenium and vitamin e as cancer chemopreventive agents in the rat prostate. Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:3 Topics: Adenocarcinoma; Alkylating Agents; alpha-Tocopherol; Androgens; Animals; Antioxidants; Cyproterone Acetate; Disease Models, Animal; Drug Therapy, Combination; Male; Methylnitrosourea; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Rats, Wistar; Selenium Compounds; Selenomethionine; Testosterone; Vitamin E	2010
Chemopreventive effects of zinc on prostate carcinogenesis induced by N-methyl-N-nitrosourea and testosterone in adult male Sprague-Dawley rats. Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:4 Topics: Acid Phosphatase; Animals; Anticarcinogenic Agents; bcl-X Protein; Body Weight; Lipid Peroxidation; Male; Methylnitrosourea; Organ Size; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Testosterone; Tumor Suppressor Protein p53; Zinc	2011
Metabolic signatures of malignant progression in prostate epithelial cells. The international journal of biochemistry & cell biology, 2011, Volume: 43, Issue:7 Topics: Amino Acids; Animals; Biomarkers, Tumor; Cell Line; Choline; Disease Progression; Epithelial Cells; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylnitrosourea; Mice; Prostate; Prostatic Neoplasms; Tumor Cells, Cultured	2011
Protective effect of zinc on N-methyl-N-nitrosourea and testosterone-induced prostatic intraepithelial neoplasia in the dorsolateral prostate of Sprague Dawley rats. Experimental biology and medicine (Maywood, N.J.), 2011, Volume: 236, Issue:9 Topics: Acid Phosphatase; Animals; Blotting, Western; Carcinogens; Male; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Prostate; Prostatic Neoplasms; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Testosterone; Tumor Suppressor Protein p53; Zinc Compounds	2011
[Influence of sodium selenite on carcinogenesis of the prostate and other organs induced by methylnitrosourea and testosterone in rats]. Voprosy onkologii, 2011, Volume: 57, Issue:4 Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Drinking Water; Lymphoma; Male; Methylnitrosourea; Orchiectomy; Precancerous Conditions; Prostatic Hyperplasia; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Rats; Rats, Wistar; Sodium Selenite; Testosterone	2011
Dietary genistein suppresses chemically induced prostate cancer in Lobund-Wistar rats. Cancer letters, 2002, Dec-01, Volume: 186, Issue:1 Topics: Animals; Anticarcinogenic Agents; Diet; Genistein; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Wistar	2002
Interrelationships among angiogenesis, proliferation, and apoptosis in the tumor microenvironment during N-methyl-N-nitrosourea androgen-induced prostate carcinogenesis in rats. Carcinogenesis, 2002, Volume: 23, Issue:10 Topics: Androgens; Animals; Apoptosis; Cell Division; Male; Methylnitrosourea; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Prostatic Neoplasms; Rats; Rats, Wistar	2002
Spontaneous mammary tumors in aging Noble rats. International journal of oncology, 2003, Volume: 22, Issue:2 Topics: 9,10-Dimethyl-1,2-benzanthracene; Age of Onset; Animals; Carcinoma; Diethylstilbestrol; Drug Implants; Estradiol; Female; Fibroadenoma; Genetic Predisposition to Disease; Incidence; Male; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Neoplasm Transplantation; Ovariectomy; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Rodent Diseases; Species Specificity; Testosterone	2003
Suppression of N-methyl-N-nitrosourea/testosterone-induced rat prostate cancer growth by celecoxib: effects on cyclooxygenase-2, cell cycle regulation, and apoptosis mechanism(s). Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-15, Volume: 9, Issue:9 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Bromodeoxyuridine; Carcinogens; Celecoxib; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Coloring Agents; Cyclin D; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cyclooxygenase 2; DNA; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Immunohistochemistry; Isoenzymes; Male; Methylnitrosourea; Microscopy, Fluorescence; Models, Biological; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Pyrazoles; Rats; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Time Factors; Tumor Suppressor Proteins	2003
Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. Journal of the National Cancer Institute, 2003, Nov-05, Volume: 95, Issue:21 Topics: Animals; Anticarcinogenic Agents; Caloric Restriction; Carcinogens; Carotenoids; Chromatography, High Pressure Liquid; Disease Models, Animal; Disease-Free Survival; Lycopene; Male; Methylnitrosourea; Powders; Proportional Hazards Models; Prostatic Neoplasms; Rats; Rats, Wistar; Solanum lycopersicum; Survival Analysis	2003
Re: Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. Journal of the National Cancer Institute, 2004, Apr-07, Volume: 96, Issue:7 Topics: Animals; Anticarcinogenic Agents; Caloric Restriction; Carotenoids; Disease Models, Animal; Drug Synergism; Lycopene; Male; Methylnitrosourea; Mice; Powders; Prostatic Neoplasms; Rats; Solanum lycopersicum; Testosterone; Vitamin E	2004
Increased phospho-AKT is associated with loss of the androgen receptor during the progression of N-methyl-N-nitrosourea-induced prostate carcinogenesis in rats. The Prostate, 2005, Jul-01, Volume: 64, Issue:2 Topics: Alkylating Agents; Animals; Disease Models, Animal; Disease Progression; Male; Methylnitrosourea; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptors, Androgen	2005
Susceptibility of Lobund-Wistar x Copenhagen hybrid rats to autochthonous prostate carcinogenesis. The Prostate, 2005, Jul-01, Volume: 64, Issue:2 Topics: Adenocarcinoma; Animals; Carcinogens; Cell Transformation, Neoplastic; Chimera; Disease Models, Animal; Genetic Predisposition to Disease; Gonadal Steroid Hormones; Male; Methylnitrosourea; Neoplasm Transplantation; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Testosterone	2005
Chemoprevention of rat prostate carcinogenesis by soy isoflavones and by Bowman-Birk inhibitor. Nutrition and cancer, 2007, Volume: 57, Issue:2 Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Cyproterone Acetate; Dose-Response Relationship, Drug; Drug Synergism; Humans; Isoflavones; Male; Methylnitrosourea; Prostatic Neoplasms; Random Allocation; Rats; Rats, Wistar; Testosterone Propionate; Time Factors; Trypsin Inhibitor, Bowman-Birk Soybean	2007
Null effect of dietary restriction on prostate carcinogenesis in the Wistar-Unilever rat. Nutrition and cancer, 2007, Volume: 57, Issue:2 Topics: Animals; Carcinogens; Cyproterone Acetate; Diet, Reducing; Dose-Response Relationship, Drug; Humans; Male; Methylnitrosourea; Prevalence; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone; Testosterone Propionate; Treatment Outcome; Weight Gain	2007
Exisulind in combination with celecoxib modulates epidermal growth factor receptor, cyclooxygenase-2, and cyclin D1 against prostate carcinogenesis: in vivo evidence. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-01, Volume: 13, Issue:19 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cyclin D1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; ErbB Receptors; Humans; Male; Methylnitrosourea; Prostatic Neoplasms; Pyrazoles; Rats; Rats, Wistar; Receptors, Androgen; Sulfonamides; Sulindac; Testosterone	2007
Protective effect of Acticoa powder, a cocoa polyphenolic extract, on prostate carcinogenesis in Wistar-Unilever rats. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2008, Volume: 17, Issue:1 Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Body Weight; Cacao; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Models, Animal; Flavonoids; Male; Methylnitrosourea; Phenols; Plant Extracts; Polyphenols; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone Propionate	2008
Adenocarcinomas of the prostate induced by N-nitroso-N-methylurea in rats pretreated with cyproterone acetate and testosterone. Cancer letters, 1983, Volume: 18, Issue:1 Topics: Adenocarcinoma; Animals; Carcinoma in Situ; Cocarcinogenesis; Cyproterone; Cyproterone Acetate; Male; Methylnitrosourea; Models, Biological; Neoplasm Metastasis; Neoplasms, Experimental; Nitrosourea Compounds; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Testosterone	1983
Gross and microscopic pathology of induced prostatic complex tumors arising in Lobund-Wistar rats. Cancer research, 1994, Feb-01, Volume: 54, Issue:3 Topics: Adenocarcinoma; Animals; Disease Models, Animal; Histiocytoma, Benign Fibrous; Male; Methylnitrosourea; Microscopy; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Rats, Wistar	1994
Chemopreventive activity of tamoxifen, N-(4-hydroxyphenyl)retinamide, and the vitamin D analogue Ro24-5531 for androgen-promoted carcinomas of the rat seminal vesicle and prostate. Cancer research, 1995, Dec-01, Volume: 55, Issue:23 Topics: Androgens; Animals; Anticarcinogenic Agents; Calcitriol; Carcinogens; Drug Screening Assays, Antitumor; Male; Methylnitrosourea; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostate; Prostatic Neoplasms; Rats; Seminal Vesicles; Tamoxifen; Testosterone	1995
Phenobarbital promotes the development of adenocarcinomas in the accessory sex glands of MNU-inoculated L-W rats. Carcinogenesis, 1995, Volume: 16, Issue:10 Topics: Abdominal Neoplasms; Adenocarcinoma; Adenoma; Aging; Animals; Carcinogens; Drug Implants; Genital Neoplasms, Male; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Methylnitrosourea; Peritoneal Neoplasms; Phenobarbital; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Seminal Vesicles; Testosterone	1995
Development and characterization of nontumorigenic and tumorigenic epithelial cell lines from rat dorsal-lateral prostate. Cancer research, 1994, Jul-01, Volume: 54, Issue:13 Topics: Acid Phosphatase; Animals; Calcitriol; Cell Division; Cell Line; Dihydrotestosterone; Epithelium; Karyotyping; Male; Methylnitrosourea; Mice; Mice, Nude; Prostate; Prostatic Neoplasms; Rats; Rats, Wistar; Receptors, Androgen; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured	1994
Activation of dormant cancer cells in the prostates and seminal vesicles of Lobund-Wistar rats. Cancer letters, 1994, Jul-29, Volume: 82, Issue:2 Topics: Adenocarcinoma; Animals; Drug Implants; Genital Neoplasms, Male; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Wistar; Seminal Vesicles; Testosterone; Time Factors	1994
Histogenesis of induced prostate and seminal vesicle carcinoma in Lobund-Wistar rats: a system for histological scoring and grading. Cancer research, 1994, Mar-15, Volume: 54, Issue:6 Topics: Animals; Evaluation Studies as Topic; Fenretinide; Genital Neoplasms, Male; Male; Methylnitrosourea; Neoplasm Staging; Prostatic Neoplasms; Rats; Rats, Wistar; Seminal Vesicles; Testosterone	1994
Procoagulant activity may be a marker of the malignant phenotype in experimental prostate cancer. British journal of cancer, 1994, Volume: 69, Issue:2 Topics: Animals; Cysteine Endopeptidases; Male; Methylnitrosourea; Neoplasm Proteins; Prostate; Prostatic Neoplasms; Rats; Rats, Wistar	1994
Expression of sulfated glycoprotein 2 is associated with carcinogenesis induced by N-nitroso-N-methylurea in rat prostate and seminal vesicle. Cancer research, 1993, Apr-01, Volume: 53, Issue:7 Topics: Animals; Biomarkers, Tumor; Blotting, Northern; Clusterin; Epithelium; Glycoproteins; Male; Methylnitrosourea; Molecular Chaperones; Prostatic Neoplasms; Rats; Seminal Vesicles	1993
Intravenous vs. intraprostatic administration of N-methyl-N-nitrosourea to induce prostate cancer in rats. The Prostate, 1996, Volume: 28, Issue:1 Topics: Adenocarcinoma; Animals; Base Sequence; Carcinogens; Codon; DNA; DNA Mutational Analysis; Dose-Response Relationship, Drug; Genes, ras; Injections, Intralesional; Injections, Intravenous; Male; Methylnitrosourea; Molecular Sequence Data; Polymerase Chain Reaction; Prostatic Neoplasms; Rats; Rats, Wistar	1996
High incidence and histogenesis of seminal vesicle adenocarcinoma and lower incidence of prostate carcinomas in the Lobund-Wistar prostate cancer rat model using N-nitrosomethylurea and testosterone. Veterinary pathology, 1996, Volume: 33, Issue:5 Topics: Adenocarcinoma; Animals; Drug Synergism; Incidence; Male; Methylnitrosourea; Neoplasm Invasiveness; Prostatic Hyperplasia; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Rats; Rats, Wistar; Seminal Vesicles; Testicular Neoplasms; Testosterone	1996
Influence of isoflavones in soy protein isolates on development of induced prostate-related cancers in L-W rats. Nutrition and cancer, 1997, Volume: 28, Issue:1 Topics: Animals; Anticarcinogenic Agents; Dietary Proteins; Genistein; Isoflavones; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Mutant Strains; Soybean Proteins	1997
Influence of N-methyl-N-nitrosourea, testosterone, and N-(4-hydroxyphenyl)-all-trans-retinamide on prostate cancer induction in Wistar-Unilever rats. Cancer research, 1998, Aug-01, Volume: 58, Issue:15 Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Cocarcinogenesis; Fenretinide; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone	1998
Chemoprevention of rat prostate carcinogenesis by 9-cis-retinoic acid. Cancer research, 1999, Feb-01, Volume: 59, Issue:3 Topics: Alitretinoin; Animals; Anticarcinogenic Agents; Carcinogens; Cyproterone Acetate; Dose-Response Relationship, Drug; Male; Methylnitrosourea; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone; Tretinoin	1999
Chemoprevention of rat prostate carcinogenesis by early and delayed administration of dehydroepiandrosterone. Cancer research, 1999, Jul-01, Volume: 59, Issue:13 Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Carcinoma; Cyproterone Acetate; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone; Time Factors	1999
Multiple pathways of prostate carcinogenesis analyzed by using cultured cells isolated from rats treated with N-methyl-N-nitrosourea and testosterone. Molecular carcinogenesis, 1999, Volume: 25, Issue:3 Topics: Animals; Base Sequence; Cell Adhesion; Cell Transformation, Neoplastic; Cells, Cultured; DNA Primers; Genes, ras; Genotype; Male; Methylnitrosourea; Mutation; Phenotype; Prostate; Prostatic Neoplasms; Rats; Species Specificity; Testosterone	1999
Prostate-seminal vesicle cancers induced in noble rats. The Prostate, 2000, Apr-01, Volume: 43, Issue:1 Topics: Animals; Disease Models, Animal; Genital Neoplasms, Male; Germ-Free Life; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Seminal Vesicles; Testosterone	2000
Human cell lines as an in vitro/in vivo model for prostate carcinogenesis and progression. The Prostate, 2001, Volume: 47, Issue:1 Topics: Alkylating Agents; Animals; Carcinogenicity Tests; Cell Adhesion; Cell Culture Techniques; Cell Division; Chromosome Aberrations; Chromosome Disorders; Disease Progression; Dose-Response Relationship, Drug; Epidermal Growth Factor; Humans; Keratins; Male; Methylnitrosourea; Mice; Mice, Nude; Nandrolone; Neoplasm Invasiveness; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Transforming Growth Factor beta; Tumor Cells, Cultured	2001
Evaluation of the chemopreventive potential of retinoids using a novel in vitro human prostate carcinogenesis model. Mutation research, 2001, Sep-20, Volume: 496, Issue:1-2 Topics: Animals; Anticarcinogenic Agents; Cell Adhesion; Cell Line, Transformed; Cell Transformation, Neoplastic; Chemoprevention; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Male; Methylnitrosourea; Mice; Mice, Nude; Mutagenicity Tests; Neoplasm Transplantation; Phenotype; Prostatic Neoplasms; Retinoids; Tumor Cells, Cultured	2001
Lack of synergism among DMAB, BOP, and MNU in induction of carcinomas of the rat ventral prostate. Teratogenesis, carcinogenesis, and mutagenesis, 1992, Volume: 12, Issue:2 Topics: Aminobiphenyl Compounds; Animals; Carcinogens; Carcinoma; Drug Synergism; Male; Methylnitrosourea; Nitrosamines; Prostatic Neoplasms; Rats; Rats, Inbred F344	1992
Early manifestations of induced prostate tumors in Lobund-Wistar rats. Cancer letters, 1992, Dec-24, Volume: 67, Issue:2-3 Topics: Animals; Disease Models, Animal; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Testosterone	1992
Animal prostate carcinoma models: limited potential for vertebral metastasis. Advances in experimental medicine and biology, 1992, Volume: 324 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Genitalia, Male; Male; Methylnitrosourea; Neoplasm Metastasis; Nitrosamines; Organ Specificity; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Species Specificity; Spinal Neoplasms; Testosterone	1992
Induction of proliferative lesions of ventral prostate, seminal vesicle, and other accessory sex glands in rats by N-methyl-N-nitrosourea: effect of castration, pretreatment with cyproterone acetate and testosterone propionate and rat strain. The Prostate, 1992, Volume: 20, Issue:4 Topics: Androgens; Animals; Cyproterone; Cyproterone Acetate; DNA Replication; DNA, Neoplasm; Genital Neoplasms, Male; Male; Methylnitrosourea; Orchiectomy; Prostatic Neoplasms; Rats; Rats, Inbred F344; Rats, Inbred Strains; Seminal Vesicles; Testis; Testosterone; Time Factors	1992
Frequent activation of the Ki-ras oncogene at codon 12 in N-methyl-N-nitrosourea-induced rat prostate adenocarcinomas and neurogenic sarcomas. Molecular carcinogenesis, 1991, Volume: 4, Issue:5 Topics: Adenocarcinoma; Animals; Base Sequence; DNA Mutational Analysis; DNA, Neoplasm; Genes, ras; Intermediate Filaments; Male; Methylnitrosourea; Molecular Sequence Data; Neurofibroma; Oligonucleotide Probes; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prostatic Neoplasms; Proto-Oncogene Proteins p21(ras); Rats	1991
Induction of invasive carcinomas of the seminal vesicles and coagulating glands of F344 rats by administration of N-methylnitrosourea or N-nitrosobis(2-oxopropyl)amine and followed by testosterone propionate with or without high-fat diet. Carcinogenesis, 1991, Volume: 12, Issue:11 Topics: Animals; Body Weight; Bulbourethral Glands; Colonic Neoplasms; Dietary Fats; Drug Synergism; Genital Neoplasms, Male; Kidney Neoplasms; Lung Neoplasms; Male; Methylnitrosourea; Nitrosamines; Organ Size; Prostate; Prostatic Neoplasms; Radioimmunoassay; Rats; Rats, Inbred F344; Seminal Vesicles; Testosterone; Urethral Neoplasms; Urinary Bladder Neoplasms	1991
Characterization of adenocarcinomas of the dorsolateral prostate induced in Wistar rats by N-methyl-N-nitrosourea, 7,12-dimethylbenz(a)anthracene, and 3,2'-dimethyl-4-aminobiphenyl, following sequential treatment with cyproterone acetate and testosterone Cancer research, 1990, Feb-01, Volume: 50, Issue:3 Topics: 9,10-Dimethyl-1,2-benzanthracene; Acid Phosphatase; Adenocarcinoma; Aminobiphenyl Compounds; Animals; Carcinoma in Situ; Cell Differentiation; Histocytochemistry; Hyperplasia; Male; Methylnitrosourea; Microscopy, Electron; Neoplasm Metastasis; Precancerous Conditions; Prostatic Neoplasms; Rats	1990
Induction of dorsolateral prostate adenocarcinomas and other accessory sex gland lesions in male Wistar rats by a single administration of N-methyl-N-nitrosourea, 7,12-dimethylbenz(a)anthracene, and 3,2'-dimethyl-4-aminobiphenyl after sequential treatment Cancer research, 1990, Feb-01, Volume: 50, Issue:3 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Aminobiphenyl Compounds; Animals; Body Weight; Cyproterone; Cyproterone Acetate; Genitalia, Male; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Sarcoma, Experimental; Survival Analysis; Testosterone	1990
[Histological and flow cytometric analyses of carcinogenesis of rat prostate cancer]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1990, Volume: 81, Issue:9 Topics: Animals; Flow Cytometry; Male; Methylnitrosourea; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Seminal Vesicles	1990
Lesions of the prostate glands and seminal vesicles induced by N-methylnitrosourea in F344 rats pretreated with ethinyl estradiol. Cancer letters, 1987, Volume: 35, Issue:1 Topics: Animals; Ethinyl Estradiol; Genital Neoplasms, Male; Male; Methylnitrosourea; Methyltestosterone; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Rats, Inbred F344; Seminal Vesicles	1987
Sequential changes in the prostate of rats treated with chlormadinone acetate, testosterone and N-nitroso-N-methylurea. The Journal of urology, 1988, Volume: 139, Issue:6 Topics: Adenocarcinoma; Animals; Chlormadinone Acetate; Male; Methylnitrosourea; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred F344; Testosterone; Time Factors	1988
The promotional effect of testosterone on induction of prostate-cancer in MNU-sensitized L-W rats. Cancer letters, 1989, Volume: 45, Issue:3 Topics: Adenocarcinoma; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Male; Methylnitrosourea; Palpation; Prostatic Neoplasms; Rats; Testosterone	1989
Production of autochthonous prostate cancer in Lobund-Wistar rats by treatments with N-nitroso-N-methylurea and testosterone. Journal of the National Cancer Institute, 1986, Volume: 77, Issue:2 Topics: Adenocarcinoma; Animals; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Testosterone	1986
Autochthonous prostate adenocarcinomas in Lobund-Wistar rats: a model system. The Prostate, 1987, Volume: 11, Issue:3 Topics: Adenocarcinoma; Animals; Disease Models, Animal; Lung Neoplasms; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Testosterone	1987