Page last updated: 2024-08-21

methylnitrosourea and Lymphoma

methylnitrosourea has been researched along with Lymphoma in 83 studies

Research

Studies (83)

Timeframe	Studies, this research(%)	All Research%
pre-1990	34 (40.96)	18.7374
1990's	28 (33.73)	18.2507
2000's	15 (18.07)	29.6817
2010's	6 (7.23)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, Z; Du, X; Gao, J; Guo, M; Huo, X; Li, C; Li, Z; Wang, C; Zhang, S	1
Chen, Z; Du, X; Guo, M; Huo, X; Li, C; Li, X; Li, Z; Tang, W; Zhang, S	1
Bailey, KL; Ball, DJ; Lorenzen, MJ; Morton, D; Stout, CL; Weaver, RJ; White, KA	1
Huang, RF; Wu, ZZ; Yu, YH	1
Huang, RF; Liu, QH; Qu, LJ; Wu, ZZ; Xiong, XS; Yu, YH; Zeng, L	1
Fan, SY; Wu, ZZ; Yu, YH	1
Murasaki, T; Nakanishi, M; Ogawa, K; Shirai, T; Sugiura, S	1
Bespalov, VG; Chepik, OF; Murazov, IaG; Panchenko, AV	1
Li, YS; Tang, HB; Xi, Y	1
Hatakeyama, K; Kodama, Y; Kominami, R; Niwa, O; Ochiai, Y; Sato, H; Tamura, Y	1
Kodama, Y; Kominami, R; Niwa, O; Takagi, R; Tamura, Y; Wakana, S; Yoshikai, Y	1
Liu, J; Ma, X; Xiang, Z	1
Angel, JM; Benavides, F; Conti, CJ; Flores, M; Fuchs-Young, R; Gomez, G; Lambertz, I; Richie, ER; Venables-Griffith, A	1
Chung, YJ; Jang, JJ; Kang, HM; Langford, C; Park, SY; Shin, SH	1
D'Eustachio, P; Guerrero, I; Pellicer, A; Villasante, A	1
Lawley, PD	1
Börzsönyi, M; Pintér, A	1
Chan, FP; Ens, B; Frei, JV	1
Kolarić, K; Roth, A; Tomek, R	1
Allay, E; Dumenco, LL; Fan, CY; Gerson, SL; Liu, L; O'Connor, PJ; Zaidi, NH	1
Bayona, W; Newcomb, EW; Pisharody, S	1
Allay, E; Ayi, TC; Dumenco, LL; Gerson, SL; Li, BF; Sy, MS; Zaidi, NH	1
Moore, J; Richie, E; Romach, E; Rummel, S	1
Kahn, JM; Mangues, R; Pellicer, A; Seidman, I	1
Ashby, J; Callander, RD; Clive, D; Glover, P; Krehl, R; Poorman-Allen, P; Tinwell, H	1
Allay, E; Dumenco, LL; Gerson, SL; Liu, L	1
Mangues, R; Oliva, MR; Pellicer, A; Saez, GT	1
Fukushima, S; Kurata, Y; Mizoguchi, M; Montesano, R; Naito, H; Shibata, MA; Tsuda, H; Wild, CP	1
Angel, JM; Richie, ER; Rinchik, EM	1
Newcomb, EW	1
Krucher, NA; Ludlow, JW	1
Ishikawa, T; Sakumi, K; Sekiguchi, M; Shimizu, S; Shiraishi, A; Tsuzuki, T	1
Allay, E; Gerson, SL; Koç, ON; McGuire, EA; Reese, JS; Sedransk, N	1
Ishikawa, T; Kawate, H; Nakatsuru, Y; Noda, T; Sakumi, K; Sekiguchi, M; Takahashi, S; Takano, H; Tsuzuki, T	1
Lord, BI; Lorimore, SA; McDonald, D; Papworth, D; Scott, D; Stones, VA; Wang, L; Woolford, LB; Wright, EG	1
Allay, E; Gerson, SL; Veigl, M	1
Charles, MW; Little, MP	1
Gerson, SL; Liu, L; Qin, X	1
Gerson, SL; Liu, L; Qin, X; Zhou, H	1
Ide, F; Ishikawa, T; Itoh, R; Kawate, H; Nakabeppu, Y; Nawata, H; Noda, T; Sakumi, K; Sekiguchi, M; Tsuzuki, T	1
Clarkin, KZ; Gomez, G; Infante, AJ; Kraig, E; Richie, ER	1
Donehower, LA; Fukuda, M; Huang, H; Ohgaki, H; Stoica, G; Tatematsu, M; Tohma, Y	1
Lanari, C; Molinolo, AA; Pazos, P	1
Fu, XY; Welte, T; Zhang, SS	1
Frei, JV; Joshi, VV	1
Allay, E; Gerson, SL; Reese, JS	1
Angel, JM; Richie, ER	1
Baines, P; Dexter, TM; Schofield, R	1
Denlinger, RH; Koestner, A; Swenberg, JA	1
Frei, JV; Lawley, PD; Swenson, DH; Warren, W	1
Koestner, A; Koestner, AW; Ruecker, FA	1
Carter, SK; Slavik, M; Wasserman, TH	1
Rao, MS; Reddy, JK	1
Denlinger, RH; Koestner, A	1
Maronpot, RR; Narisawa, T; Weisburger, JH; Wong, CQ	1
Cabral, JR; Rossi, L; Terracini, B; Testa, MC	1
Bayona, W; Brathwaite, O; Newcomb, EW	1
Angel, JM; Cloyd, MW; Richie, ER	1
Corominas, M; Newcomb, EW; Pellicer, A; Perucho, M	1
Ando, K; Hino, O; Katsuki, M; Kimura, M; Saitoh, A; Takahashi, R	1
Pellicer, A; Sloan, SR	1
Conti, CJ; Richie, ER; Rummel, SA; Stettner, SL	1
Becker, FF	1
Cordon, C; Newcomb, EW; Pellicer, A	1
Angel, JM; Morizot, DC; Richie, ER	1
Corominas, M; Diamond, LE; Guerrerro, I; Newcomb, EW; Pellicer, A; Sloan, SR	1
Dasgupta, UB; Lilly, F	1
Angel, JM; McEntire, B; Richie, ER	1
Berman, JW; Diamond, LE; Pellicer, A	1
Becker, FF; Nairn, RS; Richie, ER	1
Newcomb, EW; Pellicer, A; Steinberg, JJ	1
Babonits, M; Klein, G; Silva, S; Wiener, F	1
Gill, TJ; Hattori, A; Kunz, HW; Pan, SF; Shinozuka, H	1
Diamond, LE; Guerrero, I; Pellicer, A	1
Seidel, HJ	1
Gor'kov, VA; Kim, OA; Korman, DB	1
Fong, LY; Lui, CP; Ma-Tung, L; Ng, WL	1
Berman, JW; Diamond, L; Guerrero, I; Lake, R; Newcomb, EW; Pellicer, A; Steinberg, JJ; Villasante, A	1
Corces, V; Guerrero, I; Pellicer, A; Villasante, A	1
Demetris, AJ; Gill, TJ; Kunz, HW; Perera, MI; Shinozuka, H; Witkowski, LA	1
Hiraki, S	2

Reviews

4 review(s) available for methylnitrosourea and Lymphoma

Article	Year
DNA as a target of alkylating carcinogens. British medical bulletin, 1980, Volume: 36, Issue:1 Topics: Alkylation; Animals; Base Composition; Carcinogens; DNA; Dose-Response Relationship, Drug; Female; Humans; Lymphoma; Male; Methylnitrosourea; Mice; Mutation; Thymus Neoplasms; Time Factors	1980
Tlag1, a novel murine tumor susceptibility gene that regulates MNU-induced thymic lymphoma development. Progress in clinical and biological research, 1996, Volume: 395 Topics: Animals; Carcinogens; Chromosome Mapping; Cocarcinogenesis; Crosses, Genetic; Disease Susceptibility; Genes; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; Mice, Inbred Strains; Sequence Deletion; Species Specificity; Thymus Neoplasms	1996
Clinical comparison of the nitrosoureas. Cancer, 1975, Volume: 36, Issue:4 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carmustine; Chemical Phenomena; Chemistry; Colonic Neoplasms; Drug Therapy, Combination; Hodgkin Disease; Humans; Lomustine; Lung Neoplasms; Lymphoma; Melanoma; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Rectal Neoplasms	1975
Radiation and chemical activation of ras oncogenes in different mouse strains. Environmental health perspectives, 1989, Volume: 81 Topics: Animals; Genes, ras; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred Strains; Mutation; Neoplasms, Radiation-Induced; Species Specificity; Thymus Neoplasms; Transformation, Genetic	1989

Other Studies

79 other study(ies) available for methylnitrosourea and Lymphoma

Article	Year
Analysis of the relationship between microsatellite instability and thymic lymphoma induced by N-methyl-N-nitrosourea in C57BL/6J mice. Mutation research, 2015, Volume: 771 Topics: Alkylating Agents; Animals; Genetic Loci; Humans; Liver Neoplasms; Lymphoma; Methylnitrosourea; Mice; Microsatellite Instability; Neoplasm Metastasis; Thymus Neoplasms; Time Factors	2015
Microsatellite instability detected in tumor-related genes in C57BL/6J mice with thymic lymphoma induced by N-methyl-N-nitrosourea. Mutation research, 2015, Volume: 782 Topics: Animals; DNA Mismatch Repair; DNA Repair; Genes, Tumor Suppressor; Lymphoma; Male; Methylnitrosourea; Mice, Inbred C57BL; Microsatellite Instability; Thymoma	2015
N-Methyl-N-Nitrosourea (MNU): A positive control chemical for p53+/- mouse carcinogenicity studies. Toxicologic pathology, 2008, Volume: 36, Issue:7 Topics: Adenocarcinoma; Adenoma; Animals; Carcinogenicity Tests; Carcinogens; CD3 Complex; Duodenal Neoplasms; Female; Genes, p53; Heterozygote; Injections, Intraperitoneal; Intestine, Small; Jejunal Neoplasms; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Knockout; Neoplasms; Thymus Gland; Thymus Neoplasms	2008
[Establishment of an animal model with thymic lymphoma in mice]. Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:5 Topics: Animals; Female; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Thymus Neoplasms; Trimethylsilyl Compounds	2009
[Pathological features and ultrastructure of N-methyl-N-nitrosourea (MNU)-induced thymic lymphomas in mice]. Zhongguo shi yan xue ye xue za zhi, 2009, Volume: 17, Issue:6 Topics: Animals; Female; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Thymus Gland; Thymus Neoplasms	2009
[Improvement of mouse model for thymic lymphoma induced by N-methyl-N-nitrosourea]. Zhongguo shi yan xue ye xue za zhi, 2010, Volume: 18, Issue:4 Topics: Animals; Female; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Thymus Neoplasms	2010
Organ differences in the impact of p27(kip1) deficiency on carcinogenesis induced by N-methyl-N-nitrosourea. Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:6 Topics: Adenocarcinoma; Alkylating Agents; Animals; Antimetabolites; Body Weight; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p27; Genotype; Immunohistochemistry; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Knockout; Neoplasms; Organ Size; Organ Specificity	2013
[Influence of sodium selenite on carcinogenesis of the prostate and other organs induced by methylnitrosourea and testosterone in rats]. Voprosy onkologii, 2011, Volume: 57, Issue:4 Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Drinking Water; Lymphoma; Male; Methylnitrosourea; Orchiectomy; Precancerous Conditions; Prostatic Hyperplasia; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Rats; Rats, Wistar; Sodium Selenite; Testosterone	2011
High mobility group A1 protein acts as a new target of Notch1 signaling and regulates cell proliferation in T leukemia cells. Molecular and cellular biochemistry, 2013, Volume: 374, Issue:1-2 Topics: Animals; Base Sequence; Cell Line, Tumor; Cell Proliferation; Cyclin D; Cyclin E; Female; Gene Expression Regulation, Neoplastic; HMGA1a Protein; Humans; Leukemia, T-Cell; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Multiprotein Complexes; Receptor, Notch1; Retinoblastoma Protein; RNA Interference; RNA, Small Interfering; Sequence Analysis, DNA; Signal Transduction	2013
The D4Mit12 locus on mouse chromosome 4 provides susceptibility to both gamma-ray-induced and N-methyl-N-nitrosourea-induced thymic lymphomas. Cancer science, 2003, Volume: 94, Issue:8 Topics: Animals; Chromosome Mapping; DNA Primers; Gamma Rays; Genetic Markers; Lymphoma; Methylnitrosourea; Mice; Neoplasms, Radiation-Induced; Polymorphism, Single-Stranded Conformational; Thymus Neoplasms	2003
The D5Mit7 locus on mouse chromosome 5 provides resistance to gamma-ray-induced but not N-methyl-N-nitrosourea-induced thymic lymphomas. Carcinogenesis, 2004, Volume: 25, Issue:1 Topics: Animals; Chromosome Mapping; Gamma Rays; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred BALB C; Neoplasms, Radiation-Induced; Radiation Tolerance; Species Specificity; Thymus Neoplasms	2004
Role of IFN regulatory factor-1 and IL-12 in immunological resistance to pathogenesis of N-methyl-N-nitrosourea-induced T lymphoma. Journal of immunology (Baltimore, Md. : 1950), 2004, Jul-15, Volume: 173, Issue:2 Topics: Alkylating Agents; Animals; DNA-Binding Proteins; Genetic Predisposition to Disease; Interferon Regulatory Factor-1; Interferon-gamma; Interleukin-12; Lymphoma; Lymphotoxin-alpha; Lymphotoxin-beta; Membrane Proteins; Methylnitrosourea; Mice; Phosphoproteins	2004
Differential susceptibility to chemically induced thymic lymphomas in SENCARB and SSIN inbred mice. Molecular carcinogenesis, 2006, Volume: 45, Issue:7 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Flow Cytometry; Genetic Predisposition to Disease; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; Mice, Inbred SENCAR; Mice, Inbred Strains; Species Specificity; Thymus Neoplasms	2006
DNA copy number alterations and expression of relevant genes in mouse thymic lymphomas induced by gamma-irradiation and N-methyl-N-nitrosourea. Cancer genetics and cytogenetics, 2006, Apr-01, Volume: 166, Issue:1 Topics: Alkylating Agents; Animals; Chromosome Aberrations; Chromosomes; DNA, Neoplasm; Female; Gamma Rays; Gene Dosage; Gene Expression Profiling; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Thymus Neoplasms	2006
Isolation, characterization, and chromosome assignment of mouse N-ras gene from carcinogen-induced thymic lymphoma. Science (New York, N.Y.), 1984, Sep-07, Volume: 225, Issue:4666 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chromosome Mapping; Cloning, Molecular; Cricetinae; Deoxyribonuclease EcoRI; DNA Restriction Enzymes; Genetic Linkage; Hybrid Cells; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred Strains; Oncogenes; Thymus Neoplasms	1984
RNA oncovirus expression in N-methyl-n-nitrosourea-induced lymphomas in mice. International journal of cancer, 1981, Aug-15, Volume: 28, Issue:2 Topics: Animals; Animals, Newborn; Cocarcinogenesis; Lymphoma; Methylnitrosourea; Mice; Neoplasms, Experimental; Retroviridae; Thymus Gland; Thymus Neoplasms; Virus Activation	1981
Cytogenetics of murine thymic lymphomas induced by N-methyl-N-nitrosourea: difference in incidence of trisomy 15 in thymic lymphomas induced in neonatal and adult mice. Cancer genetics and cytogenetics, 1981, Volume: 4, Issue:4 Topics: Age Factors; Animals; Animals, Newborn; Chromosome Aberrations; Chromosome Banding; Karyotyping; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Thymus Neoplasms; Trisomy	1981
[Chemotherapy of MOPP and C-MOPP resistant cases of malignant lymphoma. (A preliminary report) (author's transl)]. Lijecnicki vjesnik, 1980, Volume: 102, Issue:6 Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lymphoma; Male; Methylnitrosourea; Middle Aged; Prednisolone; Vincristine	1980
Alkyltransferase transgenic mice: probes of chemical carcinogenesis. Mutation research, 1994, Jun-01, Volume: 307, Issue:2 Topics: Actins; Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogens; DNA Repair; Female; Gene Expression Regulation, Enzymologic; Immunoenzyme Techniques; Liver Neoplasms, Experimental; Lymphoma; Male; Methylnitrosourea; Methyltransferases; Mice; Mice, Transgenic; Models, Genetic; Nitroso Compounds; O(6)-Methylguanine-DNA Methyltransferase; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Thymus Neoplasms	1994
N-methylnitrosourea-induced Ki-ras codon 12 mutations: early events in mouse thymic lymphomas. Molecular carcinogenesis, 1995, Volume: 13, Issue:2 Topics: Animals; Base Sequence; Codon; Female; Genes, ras; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Precancerous Conditions; Thymus Gland; Thymus Neoplasms	1995
The immature thymocyte is protected from N-methylnitrosourea-induced lymphoma by the human MGMT-CD2 transgene. Carcinogenesis, 1995, Volume: 16, Issue:5 Topics: Animals; Antigens, CD; CD2 Antigens; Crosses, Genetic; Humans; In Situ Hybridization; Lymphoma; Methylnitrosourea; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Recombinant Fusion Proteins; RNA, Messenger; T-Lymphocytes; Thymus Gland	1995
Influence of sex and carcinogen treatment protocol on tumor latency and frequency of K-ras mutations in N-methyl-N-nitrosourea-induced lymphomas. Carcinogenesis, 1994, Volume: 15, Issue:10 Topics: Animals; Antigens, Differentiation; Cocarcinogenesis; Drug Administration Schedule; Female; Genes, ras; Gonadal Steroid Hormones; Injections, Intraperitoneal; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred AKR; Mutation; Orchiectomy; Ovariectomy; Phenotype; Sex Factors; Testosterone; Thymus Neoplasms	1994
An overexpressed N-ras proto-oncogene cooperates with N-methylnitrosourea in mouse mammary carcinogenesis. Cancer research, 1994, Dec-15, Volume: 54, Issue:24 Topics: Animals; Base Sequence; Genes, ras; Lymphoma; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Molecular Sequence Data; Point Mutation; Polymorphism, Restriction Fragment Length; Proto-Oncogene Mas; Sodium Chloride	1994
Potent clastogenicity of the human carcinogen etoposide to the mouse bone marrow and mouse lymphoma L5178Y cells: comparison to Salmonella responses. Environmental and molecular mutagenesis, 1994, Volume: 24, Issue:1 Topics: Animals; Bone Marrow; Etoposide; Humans; Lymphoma; Male; Methylnitrosourea; Mice; Micronucleus Tests; Mutagenicity Tests; Salmonella; Tumor Cells, Cultured	1994
Rapid repair of O6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas. Cancer research, 1994, Sep-01, Volume: 54, Issue:17 Topics: Animals; DNA; DNA Repair; Guanine; Lymphoma; Methylnitrosourea; Methyltransferases; Mice; Mice, Transgenic; O(6)-Methylguanine-DNA Methyltransferase; Species Specificity; Thymus Gland; Thymus Neoplasms	1994
Absence of MDM-2 gene amplification in experimentally induced tumors regardless of p53 status. Molecular carcinogenesis, 1994, Volume: 9, Issue:1 Topics: Animals; Base Sequence; Female; Gene Amplification; Genes, p53; Harderian Gland; Hyperplasia; Lymphoma; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred DBA; Mice, Transgenic; Molecular Sequence Data; Neoplasm Proteins; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Thymus Neoplasms	1994
Influence of aging on multi-organ carcinogenesis in rats induced by N-methyl-N-nitrosourea. Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:2 Topics: Adenocarcinoma; Aging; Animals; Bromodeoxyuridine; Deoxyguanosine; DNA; Intestinal Neoplasms; Lymphoma; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344; Splenic Neoplasms; Thymus Neoplasms; Tongue Neoplasms	1993
Clonal evolution of N-methylnitrosourea-induced C57BL/6J thymic lymphomas by analysis of multiple genetic alterations. Leukemia research, 1997, Volume: 21, Issue:3 Topics: Animals; Carcinogens; Clone Cells; Female; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mutation; Thymus Neoplasms; Trisomy	1997
Clonal evolution of N-methylnitrosourea-induced C57BL/6J thymic lymphomas by analysis of multiple genetic alterations. Leukemia research, 1997, Volume: 21, Issue:3 Topics: Animals; Carcinogens; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Thymus Neoplasms; Trisomy	1997
Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice. Cancer research, 1997, Jun-15, Volume: 57, Issue:12 Topics: Animals; Carcinogens; Gene Dosage; Liver Neoplasms; Lung Neoplasms; Lymphoma; Methylnitrosourea; Methyltransferases; Mice; Mice, Knockout; O(6)-Methylguanine-DNA Methyltransferase; Survival Rate; Thymus Neoplasms	1997
Potentiation of lymphomagenesis by methylnitrosourea in mice transgenic for LMO1 is blocked by O6-alkylguanine DNA-alkyltransferase. Oncogene, 1997, Oct-23, Volume: 15, Issue:17 Topics: Animals; Carcinogens; Codon; DNA-Binding Proteins; Genes, ras; LIM Domain Proteins; Lymphoma; Metalloproteins; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Oncogene Proteins; Point Mutation; Thymus Neoplasms; Transcription Factors	1997
Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. Proceedings of the National Academy of Sciences of the United States of America, 1998, Apr-28, Volume: 95, Issue:9 Topics: Adaptor Proteins, Signal Transducing; Alkylating Agents; Animals; Carrier Proteins; DNA Repair; Female; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Knockout; MutL Protein Homolog 1; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Survival Analysis; Thymus Neoplasms	1998
Tumour induction by methyl-nitroso-urea following preconceptional paternal contamination with plutonium-239. British journal of cancer, 1998, Volume: 78, Issue:3 Topics: Animals; Bone Marrow Cells; Cell Count; Chromosome Aberrations; Colony-Forming Units Assay; Female; Leukemia, Experimental; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred CBA; Mice, Inbred DBA; Paternal Exposure; Plutonium; Spermatozoa; Spleen; Thymus Neoplasms; Time Factors	1998
Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea. Oncogene, 1999, Jun-24, Volume: 18, Issue:25 Topics: Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; Codon; DNA Adducts; DNA Damage; DNA Methylation; Genes, ras; Guanine; Humans; Lac Operon; Lymphoma; Methylnitrosourea; Mice; Mice, Transgenic; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Organ Specificity; Point Mutation; Spleen; Thymus Gland; Thymus Neoplasms; Transgenes	1999
Tumor induction by methyl-nitroso-urea following preconceptional paternal contamination with plutonium-239. British journal of cancer, 1999, Volume: 80, Issue:3-4 Topics: Animals; Carcinogens; Fathers; Leukemia, Experimental; Lymphoma; Male; Methylnitrosourea; Mice; Plutonium	1999
Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT. Oncogene, 1999, Jul-29, Volume: 18, Issue:30 Topics: Adenosine Triphosphatases; Animals; Carcinogens; DNA Repair Enzymes; DNA-Binding Proteins; Genetic Predisposition to Disease; Humans; Hypersensitivity; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mismatch Repair Endonuclease PMS2; Models, Biological; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Proteins; Thymus Neoplasms; Time Factors	1999
Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis. Carcinogenesis, 1999, Volume: 20, Issue:9 Topics: Adenosine Triphosphatases; Animals; Carcinogens; DNA; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Drug Resistance; Genes, ras; Genetic Complementation Test; Humans; Lymphoma; Methylation; Methylnitrosourea; Mice; Mice, Knockout; Mice, Transgenic; Mismatch Repair Endonuclease PMS2; O(6)-Methylguanine-DNA Methyltransferase; Proteins; Recombinant Fusion Proteins; Thymus Neoplasms	1999
A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice. Carcinogenesis, 2000, Volume: 21, Issue:2 Topics: Adaptor Proteins, Signal Transducing; Alkylating Agents; Alleles; Animals; Carcinogens; Carrier Proteins; Codon; Disease Progression; DNA Mutational Analysis; DNA, Neoplasm; Gene Deletion; Genes, ras; Genetic Predisposition to Disease; Genotype; Intestinal Neoplasms; Lethal Dose 50; Lymphoma; Methylnitrosourea; Mice; Mice, Knockout; MutL Protein Homolog 1; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Thymus Neoplasms	2000
TCR v(beta) repertoire restriction and lack of CDR3 conservation implicate TCR-superantigen interactions in promoting the clonal evolution of murine thymic lymphomas. International immunology, 2000, Volume: 12, Issue:3 Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Cell Transformation, Neoplastic; Clonal Deletion; Cocarcinogenesis; Complementarity Determining Regions; Endogenous Retroviruses; Female; Gammaretrovirus; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Genes, bcl-2; Immunoglobulin Variable Region; Lymphoma; Male; Membrane Glycoproteins; Methylnitrosourea; Mice; Mice, Inbred AKR; Neoplasm Proteins; Precancerous Conditions; Proto-Oncogene Proteins c-bcl-2; Receptors, Antigen, T-Cell, alpha-beta; Superantigens; Thymus Neoplasms	2000
Effect of intragastric application of N-methylnitrosourea in p53 knockout mice. Molecular carcinogenesis, 2000, Volume: 28, Issue:2 Topics: Adenocarcinoma; Alleles; Animals; Carcinogens; Female; Genes, p53; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Sarcoma, Experimental; Stomach; Stomach Neoplasms	2000
Protective role of medroxyprogesterone acetate on N-methyl-N-nitrosourea-induced lymphomas in BALB/c female mice. Leukemia research, 2001, Volume: 25, Issue:2 Topics: Animals; Female; Immunohistochemistry; Incidence; Lymphoma; Medroxyprogesterone Acetate; Methylnitrosourea; Mice; Mice, Inbred BALB C	2001
Dysfunction of Stat4 leads to accelerated incidence of chemical-induced thymic lymphomas in mice. Experimental and molecular pathology, 2001, Volume: 70, Issue:3 Topics: Animals; DNA-Binding Proteins; Female; Genotype; Homozygote; Incidence; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; STAT4 Transcription Factor; Thymus Neoplasms; Time Factors; Trans-Activators	2001
Gross and microscopic changes in the lymphoreticular system during genesis of malignant lymphoma induced by a single injection of methylnitrosourea in adult mice. Journal of the National Cancer Institute, 1970, Volume: 44, Issue:2 Topics: Animals; Injections; Lymph Nodes; Lymphoma; Male; Mesentery; Methylnitrosourea; Mice; Mice, Inbred Strains; Spleen; Splenic Neoplasms; Thymus Gland; Thymus Neoplasms	1970
Overexpression of human O6-alkylguanine DNA alkyltransferase (AGT) prevents MNU induced lymphomas in heterozygous p53 deficient mice. Oncogene, 2001, Aug-30, Volume: 20, Issue:38 Topics: Alkylating Agents; Alleles; Animals; Blotting, Western; Carcinogens; DNA Adducts; Exons; Flow Cytometry; Genes, p53; Genes, ras; Heterozygote; Homozygote; Humans; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Thymus Gland; Thymus Neoplasms; Time Factors	2001
Tlag2, an N-methyl-N-nitrosourea susceptibility locus, maps to mouse chromosome 4. Molecular carcinogenesis, 2002, Volume: 33, Issue:2 Topics: Animals; Carcinogens; Chromosome Mapping; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Thymus Neoplasms	2002
Characterization of malignant cell populations in MNU-induced leukaemia of mice. Leukemia research, 1979, Volume: 3, Issue:1 Topics: Animals; Antigens, Surface; B-Lymphocytes; Female; Leukemia, Experimental; Lymphoma; Methylnitrosourea; Mice; T-Lymphocytes; Thymectomy; Thymus Gland	1979
Neoplasms in purebred boxer dogs following long-term administration of N-methyl-N-nitrosourea. Cancer research, 1978, Volume: 38, Issue:6 Topics: Animals; Carcinoma; Dogs; Female; Hemangioma; Intestinal Neoplasms; Intestine, Small; Lymphoma; Male; Methylnitrosourea; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Sarcoma, Experimental; Species Specificity; Time Factors	1978
Alkylation of deoxyribonucleic acid in vivo in various organs of C57BL mice by the carcinogens N-methyl-N-nitrosourea, N-ethyl-N-nitrosourea and ethyl methanesulphonate in relation to induction of thymic lymphoma. Some applications of high-pressure liquid The Biochemical journal, 1978, Sep-15, Volume: 174, Issue:3 Topics: Alkylation; Animals; Carcinogens; DNA; Ethyl Methanesulfonate; Ethylnitrosourea; Lymphoma; Methylnitrosourea; Mice; Neoplasms, Experimental; Thymus Neoplasms; Tissue Distribution	1978
Morphology and pathogenesis of tumors of the thymus and stomach in Sprague-Dawley rats following intragastric administration of methyl nitrosourea (MNU). International journal of cancer, 1977, Sep-15, Volume: 20, Issue:3 Topics: Animals; Lymphoma; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Stomach Neoplasms; Thymus Neoplasms; Time Factors	1977
Pancreatic adenocarcinoma in inbred guinea pigs induced by n-methyl-N-nitrosourea. Cancer research, 1975, Volume: 35, Issue:8 Topics: Adenocarcinoma; Animals; Disease Models, Animal; Female; Guinea Pigs; Intestinal Neoplasms; Lymphoma; Male; Mesentery; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Pancreas; Pancreatic Ducts; Pancreatic Neoplasms; Sex Factors; Stomach Neoplasms; Time Factors	1975
Induction of neurogenic and lymphoid neoplasms by the feeding of threshold levels of methyl- and ethylnitrousourea precursors to adult rats. Food and cosmetics toxicology, 1975, Volume: 13, Issue:6 Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Lymphoma; Mammary Neoplasms, Experimental; Methylnitrosourea; Methylurea Compounds; Neoplasms, Experimental; Nitrites; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pituitary Neoplasms; Rats; Urea	1975
Large bowel carcinogenesis in mice and rats by several intrarectal doses of methylnitrosourea and negative effect of nitrite plus methylurea. Cancer research, 1976, Volume: 36, Issue:2 Pt 1 Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Squamous Cell; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Intestinal Neoplasms; Intestine, Large; Lung Neoplasms; Lymphoma; Male; Methylnitrosourea; Mice; Nitrites; Nitrosourea Compounds; Rectal Neoplasms; Thymus Neoplasms; Urea	1976
The roles of age at treatment and dose in carcinogenesis in C3Hf/Dp mice with a single administration of N-nitroso-N-methylurea. British journal of cancer, 1976, Volume: 33, Issue:4 Topics: Age Factors; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Lung Neoplasms; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitrosourea Compounds; Stomach Neoplasms; Thymus Neoplasms	1976
p53 mutations in C57BL/6J murine thymic lymphomas induced by gamma-irradiation and N-methylnitrosourea. Cancer research, 1992, Jul-01, Volume: 52, Issue:13 Topics: Animals; Female; Gamma Rays; Genes, p53; Genes, ras; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mutation; Thymus Neoplasms; Trisomy	1992
Influence of murine leukemia proviral integrations on development of N-methyl-N-nitrosourea-induced thymic lymphomas in AKR mice. Journal of virology, 1991, Volume: 65, Issue:11 Topics: Animals; DNA, Neoplasm; DNA, Viral; Female; Leukemia Virus, Murine; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred AKR; Thymus Neoplasms; Virus Integration	1991
Differential expression of the normal and mutated K-ras alleles in chemically induced thymic lymphomas. Cancer research, 1991, Oct-01, Volume: 51, Issue:19 Topics: Animals; Blotting, Northern; DNA; Dose-Response Relationship, Drug; Gene Expression; Genes, ras; Injections, Intraperitoneal; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Nucleic Acid Hybridization; Polymerase Chain Reaction; RNA; RNA Probes; Thymus Neoplasms	1991
Chemically induced forestomach papillomas in transgenic mice carry mutant human c-Ha-ras transgenes. Cancer research, 1992, Feb-15, Volume: 52, Issue:4 Topics: Animals; Base Sequence; Dose-Response Relationship, Drug; Gene Expression; Genes, ras; Humans; Lymphoma; Methylnitrosourea; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Papilloma; Polymerase Chain Reaction; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Stomach Neoplasms	1992
Staging of T-cell receptor beta chain gene rearrangements and ras oncogene mutations in the development of murine thymic lymphomas. Cancer research, 1991, Mar-15, Volume: 51, Issue:6 Topics: Animals; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Genes, ras; Lymphoma; Methylnitrosourea; Mice; Mutation; Neoplasm Staging; Thymus Neoplasms; Time Factors	1991
N-methyl-N-nitrosourea alters thymocyte subset distribution and targets immature CD4-8+ cells for lymphoma development. Cancer research, 1991, Jan-15, Volume: 51, Issue:2 Topics: Animals; Antigens, Differentiation, T-Lymphocyte; CD4 Antigens; CD8 Antigens; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; T-Lymphocyte Subsets; Thymus Gland; Thymus Neoplasms	1991
Role of the AKR gene locus AKv-1 in susceptibility to chemical induction of thymic lymphomas. Cancer research, 1990, Oct-01, Volume: 50, Issue:19 Topics: Alleles; Animals; Disease Susceptibility; Female; Genes, Viral; Leukemia Virus, Murine; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; Organ Size; Thymus Gland; Thymus Neoplasms	1990
Comparative analysis and anatomic distribution of ras p21, IL-2R, and MEL-14 in malignant and hyperplastic murine thymus. The American journal of pathology, 1990, Volume: 136, Issue:2 Topics: Animals; Cortisone; Female; Flow Cytometry; Hyperplasia; Immunohistochemistry; Lymphoma; Methylnitrosourea; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Receptors, Immunologic; Receptors, Interleukin-2; Receptors, Lymphocyte Homing; Thymus Gland; Thymus Neoplasms	1990
Genetics of N-methyl-N-nitrosourea induction of thymic lymphomas in AKR/J mice: assignment of a susceptibility gene to mouse chromosome 7. Journal of the National Cancer Institute, 1989, Nov-01, Volume: 81, Issue:21 Topics: Albinism; Animals; Chromosome Mapping; Genes, Recessive; Genes, Viral; Leukemia Virus, Murine; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; Thymus Neoplasms	1989
General models for the generation and suppression of malignancy. Ciba Foundation symposium, 1989, Volume: 142 Topics: Animals; Chromosome Aberrations; Clone Cells; Gene Amplification; Gene Expression Regulation; Genes, Dominant; Genes, Recessive; Genetic Markers; Karyotyping; Lymphoma; Methylnitrosourea; Mice; Models, Genetic; Mutation; Neoplasms, Experimental; Oncogenes; Proto-Oncogenes; Suppression, Genetic	1989
Chemically induced murine T lymphomas: continued rearrangement within the T-cell receptor beta-chain gene during serial passage. Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:9 Topics: Animals; Chromosome Deletion; Deoxyribonuclease HindIII; DNA; DNA Restriction Enzymes; Female; Lymphoma; Methylcholanthrene; Methylnitrosourea; Mice; Receptors, Antigen, T-Cell; T-Lymphocytes	1988
N-methyl-N-nitrosourea-induced T-lymphomas of AKR/J mice contain somatically acquired ecotropic-like murine leukemia proviruses. Virology, 1988, Volume: 164, Issue:1 Topics: Animals; DNA, Neoplasm; DNA, Viral; Leukemia Virus, Murine; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; Mink Cell Focus-Inducing Viruses; Proviruses; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes; Thymus Neoplasms	1988
Differential expression of surface markers on thymic lymphomas induced by two carcinogenic agents in different mouse strains. Cellular immunology, 1987, Volume: 107, Issue:1 Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Gamma Rays; H-2 Antigens; Lymphoma; Membrane Glycoproteins; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Oncogenes; Thy-1 Antigens; Thymus Gland	1987
Proviral structure and differentiation antigen phenotype of spontaneous and chemically induced AKR lymphomas. Cancer research, 1985, Volume: 45, Issue:6 Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Ly; Antigens, Surface; DNA, Viral; Genes, Viral; Leukemia Virus, Murine; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; Phenotype; Thymus Neoplasms	1985
ras oncogenes and phenotypic staging in N-methylnitrosourea- and gamma-irradiation-induced thymic lymphomas in C57BL/6J mice. Cancer research, 1988, Oct-01, Volume: 48, Issue:19 Topics: Animals; DNA, Neoplasm; Female; Genes, ras; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Neoplasm Staging; Neoplasms, Radiation-Induced; Phenotype; T-Lymphocytes; Thymus Neoplasms	1988
Further studies on chromosome 15 trisomy in murine T-cell lymphomas: mapping of the relevant chromosome segment. International journal of cancer, 1988, May-15, Volume: 41, Issue:5 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Banding; Chromosome Mapping; Karyotyping; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; T-Lymphocytes; Trisomy	1988
Diversity of the promoting action of cyclosporine on the induction of murine lymphoid tumors. Carcinogenesis, 1988, Volume: 9, Issue:6 Topics: Animals; Carcinogens; Cyclosporins; Drug Synergism; Immunoenzyme Techniques; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Neoplasms, Radiation-Induced; Receptors, Antigen, B-Cell; Species Specificity; Thymus Neoplasms	1988
Concomitant K- and N-ras gene point mutations in clonal murine lymphoma. Molecular and cellular biology, 1988, Volume: 8, Issue:5 Topics: Alleles; Animals; Cell Transformation, Neoplastic; DNA, Neoplasm; Lymphoma; Methylnitrosourea; Mice; Mutation; Neoplasms, Radiation-Induced; Oncogenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Thymus Neoplasms; Transformation, Genetic	1988
Effects of radiation and other influences on chemical lymphomagenesis. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1987, Volume: 51, Issue:6 Topics: Animals; Bone Marrow Transplantation; Cocarcinogenesis; Female; Isoantibodies; Leukemia, Radiation-Induced; Lymphoma; Methylnitrosourea; Mice; Nitrosourea Compounds; Propionibacterium acnes; Radiation Injuries, Experimental; T-Lymphocytes	1987
[Pharmacokinetics of nitrosomethylurea in oncologic patients]. Voprosy onkologii, 1988, Volume: 34, Issue:6 Topics: Adult; Aged; Female; Humans; Lung Neoplasms; Lymphoma; Male; Melanoma; Methylnitrosourea; Middle Aged; Neoplasms	1988
Zinc-deficiency and the development of malignant lymphoma in rats given a single intragastric dose of N-methyl-N-nitrosourea. IARC scientific publications, 1987, Issue:84 Topics: Animals; Cocarcinogenesis; Lymphoma; Male; Methylnitrosourea; Rats; Rats, Inbred Strains; Zinc	1987
Oncogene activation and surface markers in mouse lymphomas induced by radiation and nitrosomethylurea. Leukemia research, 1986, Volume: 10, Issue:7 Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Chromosome Mapping; Female; Gamma Rays; Gene Expression Regulation; Leukemia, Radiation-Induced; Lymphoma; Methylnitrosourea; Mice; Oncogenes; Transcription, Genetic	1986
Loss of the normal N-ras allele in a mouse thymic lymphoma induced by a chemical carcinogen. Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:23 Topics: Alleles; Animals; Base Sequence; Brain; Chromosome Mapping; Genes, Dominant; Lymphoma; Methylnitrosourea; Mice; Mutation; Proto-Oncogenes; Thymus Neoplasms	1985
Enhancement of the induction of murine thymic lymphomas by cyclosporine. Transplantation, 1986, Volume: 41, Issue:3 Topics: Animals; Cyclosporins; Lymphoma; Male; Methylnitrosourea; Mice; Thymus Gland	1986
N,N'-dimethylnitrosourea-induced tumors in mice and Syrian hamsters. Acta medica Okayama, 1974, Volume: 28, Issue:5 Topics: Animals; Cricetinae; Female; Injections, Subcutaneous; Lung Neoplasms; Lymphoma; Male; Mammary Neoplasms, Experimental; Mediastinal Neoplasms; Methylnitrosourea; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Retroviridae; Stomach Neoplasms; Thymus Neoplasms; Transplantation, Homologous	1974
Induction of malignant lymphomas by N,N'-dimethylnitrosourea in adult mice. Gan, 1971, Volume: 62, Issue:2 Topics: Animals; Carcinogens; Female; Lymphatic Metastasis; Lymphoma; Male; Methylation; Methylnitrosourea; Mice; Microscopy, Electron; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitroso Compounds; Nitrosourea Compounds; Thymus Neoplasms; Urea	1971