methylnitrosourea has been researched along with Leukemia L 1210 in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (91.18) | 18.7374 |
| 1990's | 2 (5.88) | 18.2507 |
| 2000's | 1 (2.94) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adamson, DJ; Brockman, RW; Elliott, RD; Montgomery, JA; Riordan, JM; Shaddix, SC; Thomas, HJ | 1 |
| Shall, S | 1 |
| Lindahl-Kiessling, K; Shall, S | 1 |
| Agemori, M; Kameshita, I; Nishikimi, M; Shizuta, Y; Taniguchi, T | 1 |
| Nduka, N; Shall, S; Skidmore, CJ | 1 |
| Nduka, N; Shall, S | 1 |
| Durkacz, BW; Gray, DA; Shall, S | 1 |
| Boyle, JM; Durrant, LG; Margison, GP | 1 |
| Fornace, A; Grafstrom, RC; Harris, CC | 1 |
| Kukushkina, GV; Minenkova, EA; Peretolchina, NM; Sof'ina, ZP; Verovskiĭ, VN | 1 |
| Kasamatsu, T; Kawazoe, Y; Kohda, K | 1 |
| Gao, F; Goldman, ID; Moran, RG; Titus, S; Zhao, R | 1 |
| Fox, PA; Panasci, LC; Schein, PS | 1 |
| Abakumova, OY; Gorbachieva, LB; Kutcenko, NG; Lerman, MI; Serebryannyl, AM; Sokolova, IS | 1 |
| Mullins, DW; Schein, P; Smulson, ME; Sudhakar, S | 1 |
| Miyahara, M; Nakadate, M; Odashima, S; Suzuki, I | 1 |
| Davies, MI; Goodwin, PM; Halldorsson, H; Lewis, PJ; Shall, S; Skidmore, CJ; Zia'ee, AA | 1 |
| Pinsky, SD; Smulson, ME; Tew, KD; Woolley, PV | 1 |
| Kamiya, S; Maekawa, A; Miyahara, M; Odashima, S | 1 |
| Ewig, RA; Kohn, KW | 1 |
| Schepartz, SA | 1 |
| Schabel, FM | 1 |
| Frankfurt, OS; Ostrovskaia, LA | 1 |
| Bunto, TV; Gorbacheva, LB; Ostrovskaia, LA; Sokolova, IS | 1 |
| Dederer, LIu; Gorbacheva, LB; Kukushkina, GV | 1 |
| Elksne, SJ; Gorbacheva, LB; Kukushkina, GV; Miniker, TD; Preobrazhenskaya, MN | 1 |
| Boyle, JM | 1 |
| Hara, H; Hiroi, M; Moriki, T; Shizuta, Y; Taniguchi, T; Yamane, T | 1 |
| Durdeva, AD; Gorbacheva, LB; Kukushkina, GV; Ponomarenko, NA | 1 |
| Durdyeva, ED; Gorbacheva, LB; Kukushkina, GV; Ponomarenko, NA | 1 |
| Chen, CF; Otter, GM; Schmid, FA | 1 |
| Hakura, A; Kawazoe, Y; Kohda, K | 1 |
| Durdyeva, ED; Gorbacheva, KB; Kukushkina, GV | 1 |
| Enzan, H; Hara, H; Shizuta, Y; Taniguchi, T | 1 |
1 review(s) available for methylnitrosourea and Leukemia L 1210
| Article | Year |
|---|---|
Nitrosoureas: a review of experimental antitumor activity.
Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Leukemia L1210; Lomustine; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Semustine | 1976 |
33 other study(ies) available for methylnitrosourea and Leukemia L 1210
| Article | Year |
|---|---|
Nitrosoureido nucleosides as potential inhibitors of nucleotide biosynthesis.
Topics: Animals; Carmustine; Cell Division; DNA Replication; Drug Stability; Indicators and Reagents; Leukemia L1210; Lomustine; Mice; Neoplasm Proteins; Nitrosourea Compounds; Nucleosides; Nucleotides; Structure-Activity Relationship; Transcription, Genetic | 1988 |
Inhibition of DNA repair by inhibitors of nuclear ADP-ribosyl transferase.
Topics: Animals; Benzamides; Cell Nucleus; Cells, Cultured; Chromosome Aberrations; DNA Repair; Humans; Kinetics; Leukemia L1210; Methylnitrosourea; Mice; NAD; Nucleotidyltransferases; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Sister Chromatid Exchange; Xeroderma Pigmentosum | 1984 |
DNA repair and sister chromatid exchanges.
Topics: Animals; Benzamides; Cell Line; DNA Repair; Leukemia L1210; Methylnitrosourea; Mice; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Sister Chromatid Exchange; Sulfuric Acid Esters | 1984 |
Participation of poly(ADP-ribosyl)ation in the depression of RNA synthesis caused by treatment of mouse lymphoma cells with methylnitrosourea.
Topics: Animals; Benzamides; Kinetics; Leukemia L1210; Methylnitrosourea; Mice; NAD+ Nucleosidase; Nitrosourea Compounds; Nucleoside Diphosphate Sugars; Poly A; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; RNA; RNA, Messenger; RNA, Neoplasm; RNA, Ribosomal; Transcription, Genetic | 1982 |
The enhancement of cytotoxicity of N-methyl-N-nitrosourea and of gamma-radiation by inhibitors of poly(ADP-ribose) polymerase.
Topics: Animals; Cells, Cultured; Drug Synergism; Enzyme Inhibitors; Gamma Rays; Leukemia L1210; Methylnitrosourea; Mice; NAD+ Nucleosidase; Niacinamide; Nicotinic Acids; Nitrosourea Compounds; Poly(ADP-ribose) Polymerase Inhibitors | 1980 |
5-Methylnicotinamide-resistant variant of mouse lymphoma L1210 cells.
Topics: Animals; Cell Line; Cell Survival; Drug Resistance; Gamma Rays; Leukemia L1210; Methylnitrosourea; Mice; NAD+ Nucleosidase; Niacinamide; Poly(ADP-ribose) Polymerases | 1980 |
Inhibitors of nuclear ADP-ribosyl transferase retard DNA repair after N-methyl-N-nitroso-urea. Further evidence for the involvement of (ADP-ribose)n in DNA repair.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Division; Centrifugation, Density Gradient; Deoxycytidine; DNA Repair; Leukemia L1210; Methylnitrosourea; Mice; Niacinamide; Nitrosourea Compounds; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Thymidine | 1981 |
Effects of 5-methylnicotinamide on mouse L1210 cells exposed to N-methyl-N-nitrosourea: mutation induction, formation and removal of methylation products in DNA, and unscheduled DNA synthesis.
Topics: Animals; Cells, Cultured; DNA Repair; DNA, Neoplasm; Leukemia L1210; Methylation; Methylnitrosourea; Mice; Mutagens; Niacinamide; Nitrosourea Compounds; Purines | 1981 |
Repair of DNA damage caused by formaldehyde in human cells.
Topics: Animals; Bronchi; Cell Line; DNA Repair; Epithelium; Fibroblasts; Formaldehyde; Humans; Kinetics; Leukemia L1210; Methylnitrosourea; Mice; Skin; Xeroderma Pigmentosum | 1984 |
[Disruption of DNA synthesis and structure of mouse L1210 leukemia cells, sensitive and resistant to 1-methyl-1 nitrosourea and 1,3-bis(2-chloroethyl)-1-nitrosourea in vivo].
Topics: Animals; Carmustine; Centrifugation, Density Gradient; Chromosome Aberrations; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance; Leukemia L1210; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Weight; Nitrosourea Compounds; Nucleic Acid Conformation | 1984 |
Comparison of chemically induced DNA breakage in cellular and subcellular systems using the comet assay.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antimetabolites, Antineoplastic; Bleomycin; DNA; DNA Damage; Fluorouracil; Hydrogen Peroxide; Leukemia L1210; Methotrexate; Methylnitrosourea; Mice; Mutagenicity Tests; Mutagens; Subcellular Fractions; Tumor Cells, Cultured | 1996 |
Molecular analysis of murine leukemia cell lines resistant to 5, 10-dideazatetrahydrofolate identifies several amino acids critical to the function of folylpolyglutamate synthetase.
Topics: Amino Acid Sequence; Amino Acids; Animals; Antimetabolites, Antineoplastic; Carcinogens; Cricetinae; Folic Acid Antagonists; Lacticaseibacillus casei; Leukemia L1210; Methotrexate; Methylnitrosourea; Mice; Molecular Sequence Data; Peptide Synthases; Protein Conformation; Sequence Alignment; Structure-Activity Relationship; Tetrahydrofolates; Transfection | 2000 |
Structure-activity studies of methylnitrosourea antitumor agents with reduced murine bone marrow toxicity.
Topics: Alkylation; Animals; Bone Marrow; Cells, Cultured; Chemical Phenomena; Chemistry; DNA, Neoplasm; Galactose; Glucose; In Vitro Techniques; Leukemia L1210; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Proteins; Nitrosourea Compounds; RNA, Neoplasm; Streptozocin; Structure-Activity Relationship | 1977 |
Utilization of in vivo alkylated metabolites as a possible cause of increased sensitivity to tumor cells to alkylating agents.
Topics: Animals; Carcinoma, Hepatocellular; DNA, Neoplasm; Leukemia L1210; Liver; Liver Neoplasms; Methylnitrosourea; Mice; Mice, Inbred Strains; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Nitrosourea Compounds; RNA, Neoplasm; Time Factors | 1975 |
A putative role for nicotinamide adenine dinucleotide-promoted nuclear protein modification in the antitumor activity of N-methyl-N-nitrosourea.
Topics: Alkylation; Animals; DNA; DNA Repair; DNA-Directed DNA Polymerase; DNA, Single-Stranded; HeLa Cells; Histones; Leukemia L1210; Methylnitrosourea; NAD; Nitrosourea Compounds; Nucleoproteins; Polynucleotide Adenylyltransferase; Streptozocin | 1977 |
Sensitivity difference of rat ascites hepatoma AH-13 and mouse leukemia L-1210 to nitrosourea derivatives.
Topics: Animals; Carcinoma, Hepatocellular; Leukemia L1210; Liver Neoplasms; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Structure-Activity Relationship | 1978 |
The involvement of poly(ADP-ribose) polymerase in the degradation of NAD caused by gamma-radiation and N-methyl-N-nitrosourea.
Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Kinetics; Leukemia L1210; Methylnitrosourea; Mice; NAD; NAD+ Nucleosidase; Nitrosourea Compounds; Poly(ADP-ribose) Polymerases; Thymidine | 1979 |
Modification of L1210 cell nuclear proteins by 1-methyl-1-nitrosourea and 1-methyl-3-nitro-1-nitrosoguanidine.
Topics: Animals; Cells, Cultured; Histones; Leukemia L1210; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasm Proteins; Nitrosourea Compounds; Nucleoproteins; Protein Binding | 1979 |
Antitumor effect of pyridine N-oxides having 1-(2-chloroethyl)-1-nitrosoureidoalkyl and 1-methyl-1-nitrosoureidoalkyl groups.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Drug Evaluation, Preclinical; Leukemia L1210; Liver Neoplasms, Experimental; Methylnitrosourea; Mice; Nitrogen Mustard Compounds; Nitrosourea Compounds; Pyridines; Rats; Solubility; Time Factors | 1979 |
DNA damage and repair in mouse leukemia L1210 cells treated with nitrogen mustard, 1,3-bis(2-chloroethyl)-1-nitrosourea, and other nitrosoureas.
Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Leukemia L1210; Lomustine; Mechlorethamine; Methylnitrosourea; Neoplasm Proteins; Nitrosourea Compounds | 1977 |
Early history and development of the nitrosoureas.
Topics: Animals; Carmustine; History, 20th Century; Leukemia L1210; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Nitrosourea Compounds; United States | 1976 |
[Effect of N-nitroso-N'-methylurea on the cellular kinetics in tumors].
Topics: Animals; Cell Count; DNA, Neoplasm; Female; Kinetics; Leukemia L1210; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mitosis; Nitrosourea Compounds; Thymidine; Time Factors; Tritium | 1977 |
[Effect of N-nitroso-N-methylurea on DNA and RNA synthesis in cells of liver and spleen tumors in leucosis L-1210].
Topics: Animals; DNA, Neoplasm; Leukemia L1210; Leukopenia; Liver Neoplasms; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nitrosourea Compounds; RNA, Neoplasm; Splenic Neoplasms; Thymidine; Uridine | 1976 |
[Effect of N-methyl-N-nitrosourea on the synthesis and processing of RNA in Ehrlich ascitic carcinoma and leukemia L1210 cells].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cyanates; In Vitro Techniques; Leukemia L1210; Methylnitrosourea; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Protein Biosynthesis; Rifampin; RNA, Neoplasm | 1975 |
O6-methylguanine as a modulator of antitumor activity of N-alkyl-N-nitrosoureas in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; DNA Damage; DNA, Neoplasm; Drug Interactions; Drug Resistance; Guanine; Leukemia L1210; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Nucleic Acid Conformation; Time Factors | 1991 |
Poly (ADP-ribose) metabolism in alkylated mouse L5178Y cells.
Topics: Alkylation; Animals; Carbon Radioisotopes; Cell Division; Formates; Kinetics; Leukemia L1210; Leukemia L5178; Leukemia, Experimental; Methylnitrosourea; Mice; NAD; NAD+ Nucleosidase; Nitrosourea Compounds; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases | 1985 |
Effects of methylnitrosourea on visualization of acridine orange binding to DNA in mouse lymphoma L-1210 cells.
Topics: Acridine Orange; Animals; Benzamides; DNA, Neoplasm; Leukemia L1210; Methylnitrosourea; Mice; Microscopy, Electron; Poly(ADP-ribose) Polymerase Inhibitors; Transcription, Genetic; Uridine | 1986 |
In vivo DNA damage and resistance to 1-methyl-1-nitrosourea and 1,3-bis(2-chloroethyl)-1-nitrosourea in L1210 leukemia cells.
Topics: Animals; Carmustine; DNA Damage; DNA Repair; DNA-Directed DNA Polymerase; Drug Resistance; Ethidium; In Vitro Techniques; Leukemia L1210; Methylnitrosourea; Mice; Poly(ADP-ribose) Polymerases; Time Factors | 1988 |
[The role of N-nitrosourea-induced changes in the nucleoid structure and activity of repair enzymes in the development of drug resistance in mice with leukemia L1210].
Topics: Animals; Carmustine; Cell Nucleus; DNA Repair; DNA-Directed DNA Polymerase; DNA, Neoplasm; Drug Resistance; Enzyme Activation; Leukemia L1210; Methylnitrosourea; Mice; Tumor Cells, Cultured | 1987 |
Drug sensitivity of methylnitrosourea- and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea-resistant L1210 lines.
Topics: Alkylating Agents; Animals; Antimetabolites, Antineoplastic; Cell Line; Cell Survival; Drug Administration Schedule; Drug Resistance; In Vitro Techniques; Karyotyping; Leukemia L1210; Methylnitrosourea; Mice; Mutagens; Neoplasm Transplantation; Semustine | 1986 |
Studies on chemical carcinogens and mutagens. XXIX. Mutagenic N-trimethylsilylmethyl-N-nitrosourea as a biological alkylating agent equivalent to N-methyl-N-nitrosourea (MNU).
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Cricetulus; Escherichia coli; Leukemia L1210; Lung; Methylnitrosourea; Mice; Mutagenicity Tests; Mutagens; Mutation; Nitrosourea Compounds; Salmonella typhimurium; Silicon; Trimethylsilyl Compounds | 1985 |
[Relation between the changes in the structure and synthesis of DNA in the cells of mouse leukemia L1210 induced by 1-methyl-1-nitrosourea and 1,3-bis(2-chloroethyl)-1-nitrosourea].
Topics: Animals; Carmustine; DNA Repair; DNA Replication; DNA, Neoplasm; DNA, Single-Stranded; Kinetics; Leukemia L1210; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Time Factors | 1986 |
Nuclear chromatin condensation of mouse lymphoma (L-1210) cells by methylnitrosourea. An electron microscopic and biochemical study.
Topics: Animals; Cell Nucleus; Cells, Cultured; Chromatin; Leukemia L1210; Methylnitrosourea; Mice; Microscopy, Electron; Nitrosourea Compounds | 1985 |