methylnitrosourea has been researched along with Genetic Predisposition in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 14 (63.64) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ji, J; Jiang, Y; Liu, X; Qi, X; Ren, J; Yu, Y; Zhang, J; Zhu, Z | 1 |
| Amin, SG; Belinsky, SA; Collins, LB; Crowell, RE; Desai, D; Gilliland, FD; Jauregui, AR; Juri, DE; Leng, S; Lin, Y; Liu, Y; Picchi, MA; Stidley, CA; Swenberg, JA; Tellez, CS; Thomas, CL; Wathelet, MG; Wu, G; Zhang, X | 1 |
| Chan, AW; Cheng, AS; Ching, AK; Chong, WW; Chui, YL; Fan, DM; Go, MY; Leung, WK; Sung, JJ; To, KF; Wang, X; Wong, CY; Wu, KC; Yu, J | 1 |
| Arumugam, A; Castillo, R; de la Torre, A; Elsayed, A; Hernandez, C; Kotkowski, E; Rajkumar, L; Schecter, S | 1 |
| Dai, H; Hua, Y; Shen, B; Xu, H; Zheng, L; Zhou, M | 1 |
| Gould, MN; Haag, JD; Mau, B; Samuelson, DJ; Sharma, D; Smits, BM; Woditschka, S | 1 |
| Fukamachi, K; Han, BS; Maeda, M; Ohnishi, T; Takasuka, N; Tsuda, H; Yamasaki, T | 1 |
| Chan, FL; Chen, ZY; Cheung, SY; Choi, HL; Huang, Y; James, AE | 1 |
| Liu, J; Ma, X; Xiang, Z | 1 |
| Pollard, M; Suckow, MA; Wolter, W | 1 |
| Angel, JM; Benavides, F; Conti, CJ; Flores, M; Fuchs-Young, R; Gomez, G; Lambertz, I; Richie, ER; Venables-Griffith, A | 1 |
| Archer, MC; Ealey, KN; Lu, S | 1 |
| Anisimov, VN; Gvardina, OE | 1 |
| Brennan, LA; Jongstra, J; Wielowieyski, A | 1 |
| Gerson, SL; Liu, L; Qin, X | 1 |
| Asamoto, M; Ochiya, T; Ota, T; Sekiya, T; Terada, M; Toriyama-Baba, H; Tsuda, H | 1 |
| Ide, F; Ishikawa, T; Itoh, R; Kawate, H; Nakabeppu, Y; Nawata, H; Noda, T; Sakumi, K; Sekiguchi, M; Tsuzuki, T | 1 |
| Donehower, LA; Furihata, C; Ohgaki, H; Sakai, H; Shirai, N; Tatematsu, M; Tsukamoto, T; Yamamoto, M; Yoshida, K | 1 |
| Gould, MN; Haag, JD; Thompson, TA | 1 |
| Heddle, JA; Shima, N; Swiger, RR | 1 |
| Bouffler, SD; Cox, R; Fodde, R; Hofland, N | 1 |
| Asamoto, M; Naito, A; Ochiya, T; Ota, T; Sekiya, T; Terada, M; Toriyama-Baba, H; Tsuda, H | 1 |
22 other study(ies) available for methylnitrosourea and Genetic Predisposition
| Article | Year |
|---|---|
Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; DNA Damage; DNA Repair; F-Box-WD Repeat-Containing Protein 7; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Gene Order; Gene Targeting; Genes, myc; Genetic Loci; Genetic Predisposition to Disease; Genotype; Haploinsufficiency; Methylnitrosourea; Mice; Mice, Knockout; Models, Biological; Stomach Neoplasms | 2017 |
Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung.
Topics: Base Sequence; Chromosomes, Human, Pair 15; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Epithelial Cells; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Genome-Wide Association Study; Guanine; Humans; Longitudinal Studies; Lung Neoplasms; Male; Methylation; Methylnitrosourea; Molecular Sequence Data; Polymorphism, Single Nucleotide; Smoking; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2015 |
Transgenic cyclooxygenase-2 expression and high salt enhanced susceptibility to chemical-induced gastric cancer development in mice.
Topics: Animals; Apoptosis; Cell Division; Cyclooxygenase 2; DNA; Female; Genetic Predisposition to Disease; Humans; Methylnitrosourea; Mice; Mice, Transgenic; Oviducts; Pseudopregnancy; Sodium Chloride, Dietary; Stomach Neoplasms | 2008 |
Long-term hormonal promotion overcomes genetic resistance to mammary cancer.
Topics: Animals; Estradiol; Female; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Progesterone; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Time Factors | 2011 |
Chemical-induced cancer incidence and underlying mechanisms in Fen1 mutant mice.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line; Chromosome Aberrations; Disease Models, Animal; DNA Breaks, Double-Stranded; DNA Repair; DNA Replication; Flap Endonucleases; Genetic Predisposition to Disease; Hydrogen Peroxide; Lung Neoplasms; Methylnitrosourea; Mice; Mice, Mutant Strains; Microscopy, Fluorescence; Point Mutation | 2011 |
The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Breast Neoplasms; CD4-Positive T-Lymphocytes; CD8 Antigens; Cytokines; Epithelial Cells; Female; Genetic Loci; Genetic Predisposition to Disease; Homeostasis; L-Selectin; Mammary Neoplasms, Experimental; Methylnitrosourea; NK Cell Lectin-Like Receptor Subfamily B; Rats; Rats, Inbred WKY; Receptors, Antigen, T-Cell; T-Lymphocytes; Th1 Cells; Th2 Cells | 2011 |
Inhibitory effects of 17beta-estradiol and 4-n-octylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Estradiol; Female; Gene Transfer Techniques; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenols; Proto-Oncogene Mas; Rats; Tumor Cells, Cultured | 2002 |
Spontaneous mammary tumors in aging Noble rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age of Onset; Animals; Carcinoma; Diethylstilbestrol; Drug Implants; Estradiol; Female; Fibroadenoma; Genetic Predisposition to Disease; Incidence; Male; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Neoplasm Transplantation; Ovariectomy; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Rodent Diseases; Species Specificity; Testosterone | 2003 |
Role of IFN regulatory factor-1 and IL-12 in immunological resistance to pathogenesis of N-methyl-N-nitrosourea-induced T lymphoma.
Topics: Alkylating Agents; Animals; DNA-Binding Proteins; Genetic Predisposition to Disease; Interferon Regulatory Factor-1; Interferon-gamma; Interleukin-12; Lymphoma; Lymphotoxin-alpha; Lymphotoxin-beta; Membrane Proteins; Methylnitrosourea; Mice; Phosphoproteins | 2004 |
Susceptibility of Lobund-Wistar x Copenhagen hybrid rats to autochthonous prostate carcinogenesis.
Topics: Adenocarcinoma; Animals; Carcinogens; Cell Transformation, Neoplastic; Chimera; Disease Models, Animal; Genetic Predisposition to Disease; Gonadal Steroid Hormones; Male; Methylnitrosourea; Neoplasm Transplantation; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Testosterone | 2005 |
Differential susceptibility to chemically induced thymic lymphomas in SENCARB and SSIN inbred mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Flow Cytometry; Genetic Predisposition to Disease; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; Mice, Inbred SENCAR; Mice, Inbred Strains; Species Specificity; Thymus Neoplasms | 2006 |
Development of aberrant crypt foci in the colons of ob/ob and db/db mice: evidence that leptin is not a promoter.
Topics: Animals; Carcinogens; Colorectal Neoplasms; Cytochrome P-450 CYP2E1; Genetic Predisposition to Disease; Leptin; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Obese; Microsomes; Promoter Regions, Genetic; Receptors, Leptin | 2008 |
N-nitrosomethylurea-induced carcinogenesis in the progeny of male rats of different ages.
Topics: Animals; Female; Genetic Predisposition to Disease; Genomic Imprinting; Germ-Line Mutation; Kidney Neoplasms; Male; Methylnitrosourea; Paternal Age; Rats | 1995 |
Tli1, a resistance locus for carcinogen-induced T-lymphoma.
Topics: Animals; Carcinogens; Chromosome Mapping; Genetic Predisposition to Disease; Immunity, Innate; Lymphoma, T-Cell; Methylnitrosourea; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred Strains; Microsatellite Repeats; Species Specificity | 1999 |
Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.
Topics: Adenosine Triphosphatases; Animals; Carcinogens; DNA Repair Enzymes; DNA-Binding Proteins; Genetic Predisposition to Disease; Humans; Hypersensitivity; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mismatch Repair Endonuclease PMS2; Models, Biological; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Proteins; Thymus Neoplasms; Time Factors | 1999 |
Transgenic rats carrying human c-Ha-ras proto-oncogenes are highly susceptible to N-methyl-N-nitrosourea mammary carcinogenesis.
Topics: Animals; Animals, Genetically Modified; Carcinogens; Cocarcinogenesis; Codon; DNA Mutational Analysis; DNA, Neoplasm; Female; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Transfection | 2000 |
A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice.
Topics: Adaptor Proteins, Signal Transducing; Alkylating Agents; Alleles; Animals; Carcinogens; Carrier Proteins; Codon; Disease Progression; DNA Mutational Analysis; DNA, Neoplasm; Gene Deletion; Genes, ras; Genetic Predisposition to Disease; Genotype; Intestinal Neoplasms; Lethal Dose 50; Lymphoma; Methylnitrosourea; Mice; Mice, Knockout; MutL Protein Homolog 1; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Thymus Neoplasms | 2000 |
p53 knockout mice (-/-) are more susceptible than (+/-) or (+/+) mice to N-methyl-N-nitrosourea stomach carcinogenesis.
Topics: Animals; Carcinogens; Cocarcinogenesis; Female; Gastric Mucosa; Gene Dosage; Genes, p53; Genetic Predisposition to Disease; Heterozygote; Male; Methylnitrosourea; Mice; Mice, Knockout; Mutation; Pepsinogen A; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Precancerous Conditions; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2000 |
ras gene mutations are absent in NMU-induced mammary carcinomas from aging rats.
Topics: Aging; Animals; Carcinogens; Cocarcinogenesis; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Rats; Rats, Inbred WF; Transcriptional Activation | 2000 |
Dietary restriction during murine development provides protection against MNU-induced mutations.
Topics: Animals; Base Sequence; DNA Primers; Energy Intake; Feeding Behavior; Female; Genetic Predisposition to Disease; Litter Size; Methylnitrosourea; Mice; Mutation; Neoplasms, Experimental; Pregnancy; Transcription Factors; Viral Proteins | 2000 |
Evidence for Msh2 haploinsufficiency in mice revealed by MNU-induced sister-chromatid exchange analysis.
Topics: Animals; Base Pair Mismatch; Chromosome Aberrations; Chromosome Fragility; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Disease Models, Animal; DNA Repair; DNA-Binding Proteins; Genetic Predisposition to Disease; Haplotypes; Loss of Heterozygosity; Methylnitrosourea; Mice; MutS Homolog 2 Protein; Proto-Oncogene Proteins; Radiation, Ionizing; Sister Chromatid Exchange | 2000 |
High susceptibility of transgenic rats carrying the human c-Ha-ras proto-oncogene to chemically-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Rats | 2001 |