Compounds > methylnitrosourea
Page last updated: 2024-08-21

methylnitrosourea and Experimental Mammary Neoplasms

methylnitrosourea has been researched along with Experimental Mammary Neoplasms in 723 studies

Research

Studies (723)

TimeframeStudies, this research(%)All Research%
pre-1990218 (30.15)18.7374
1990's227 (31.40)18.2507
2000's164 (22.68)29.6817
2010's100 (13.83)24.3611
2020's14 (1.94)2.80

Authors

AuthorsStudies
Carvalho Dartora, VFM; Costa, SKP; Fantini, MCA; Lopes, LB; Machado-Neto, JA; Malagó, ID; Marçal Pessoa, AF; Salata, GC1
Daino, K; Imaoka, T; Kakinuma, S; Kokubo, T; Nishimura, M; Nishimura, Y; Shimada, Y; Takabatake, M1
Dygai, AM; Ermakova, NN; Kogai, LV; Krupin, VA; Kubatiev, AA; Morozov, SG; Pakhomova, AV; Pan, ES; Pershina, OV; Rybalkina, OY; Sandrikina, LA; Skurikhin, EG; Zhukova, MA1
Aldosary, S; Ansari, MN; Kaithwas, G; Kasna, S; Roy, S; Saeedan, AS; Singh, M1
Bondarenko, NA; Kabakov, AV; Kazakov, OV; Kim, II; Konenkov, VI; Letyagin, AY; Lykov, AP; Orlov, NB; Poveshchenko, AF; Poveshchenko, OV; Raiter, TV; Strunkin, DN1
Bondarenko, NA; Kabakov, AV; Kazakov, OV; Kim, II; Konenkov, VI; Letyagin, AY; Lykov, AP; Poveshchenko, AF; Poveshchenko, OV; Strunkin, DN1
Bogachev, SS; Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Poveshchenko, AF; Raiter, TV; Strunkin, DN1
Bogachev, SS; Bondarenko, NA; Kabakov, AV; Kazakov, OV; Kim, II; Konenkov, VI; Lykov, AP; Orlov, NB; Poveshchenko, AF; Poveshchenko, OV; Raiter, TV; Strunkin, DN1
Dokduang, S; Graidist, P; Lailerd, N; Madla, S; Rattanaburee, T; Sriwiriyajan, S; Sukpondma, Y; Tedasen, A; Tipmanee, V1
Jaafar, H; Jaffar, NFN; Muhammad Sakri, MS; Tengku Din, TADA; Wan Abdul Rahman, WF1
Adaramoye, OA; Adebayo, OA; Akinloye, O1
Han, C; Han, H; Yang, C; Zhang, G; Zhang, Y1
Ansari, MN; Choudhary, A; Kaithwas, G; Kumar, D; Raj, R; Rastogi, S; Saeedan, AS; Singh, L; Singh, M1
Cernackova, A; Horvathova, L; Macejova, D; Mravec, B; Tibensky, M; Tillinger, A1
Faustino-Rocha, AI; Ferreira, R; Gama, A; Ginja, M; Neuparth, MJ; Oliveira, PA1
Fang, M; Kang, HG; Ohman Strickland, PA; Zarbl, H1
Ananthakrishnan, D; Gunasekaran, K; Jayaganesh, R; Pugalendhi, P; Rajakumar, T1
Cegielski, M; Dziegiel, P; Grzegrzolka, J; Kobierzycki, C; Malicka, I; Paslawska, U; Piotrowska, A; Podhorska-Okolow, M; Siewierska, K; Wozniewski, M1
Britton, SL; Jones, LW; Koch, LG; McGinley, JN; Neil, ES; Thompson, HJ1
Bolton, JL; Chen, SN; Dietz, BM; Goerl, F; Keiler, AM; Macejova, D; Muders, MH; Nikolic, D; Pauli, GF; van Breemen, RB; Vollmer, G; Zierau, O1
Baraya, YS; Mustapha, Z; Wong, KK; Yaacob, NS; Yankuzo, HM1
Ishchenko, IY; Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Michurina, SV; Poveshchenko, AF; Raiter, TV; Strunkin, DN1
Idris, F; Jaafar, H; Mohd Nafi, SN1
Bin-Meferij, MM; El-Kott, AF1
Bohmdorfer, M; Demeckova, V; Jager, W; Jendzelovska, Z; Kiktava, M; Kiskova, T; Thalhammer, T; Venglovska, K1
Alexandrov, VA; Baranenko, DA; Bespalov, VG; Kostikova, VA; Semenov, AL; Vysochina, GI1
Aldossary, SA; Ansari, MN; Gautam, S; Kaithwas, G; Rani, S; Saeedan, AS1
Kaithwas, G; Pandey, R; Roy, S; Sammi, SR; Singh, M1
Beger, RD; Grubbs, CJ; Lubet, RA; Luster, J; Miller, MS; Seifried, HE1
Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Poveshchenko, AF; Poveshchenko, OV; Raiter, TV; Strunkin, DN1
Adaramoye, O; Adefisan, A; Owumi, S1
Adamkov, M; Bojková, B; Kajo, K; Kubatka, P; Péč, M; Solár, P1
Pachaiappan, P; Subbaiyan, T; Thangarasu, R1
Grubbs, CJ; Hill, DL; Khazal, KF; Samuel, T1
Colaço, B; Colaço, J; da Costa, RG; Faustino-Rocha, A; Ferreira, R; Ginja, M; Oliveira, PA; Pinho-Oliveira, J; Pires, MJ; Soares-Maia, R; Teixeira-Guedes, C1
Bae, S; Cho, K; Mabasa, L; Park, CS; Walters, MW1
Bortner, JD; Das, A; El-Bayoumy, K; Manni, A; Skibinski, CG; Stanley, A; Stanley, BA; Thompson, HJ1
Faustino-Rocha, AI; Ferreira, R; Gabriel, J; Gama, A; Gil da Costa, R; Ginja, M; Lopes, C; Oliveira, PA; Silva, A; Teixeira-Guedes, CI1
Barathidasan, R; Dhama, K; Pawaiya, RS; Rai, RB1
Bai, X; Chen, Z; Dai, Y; Gao, Q; Gao, T; Jia, C; Lai, P; Lin, J; Ren, Z; Song, Q; Wan, Z; Wang, Y; Zhang, Y; Zhao, A; Zhao, Z; Zheng, H; Zhou, X1
da Costa, R; Faria, F; Faustino-Rocha, A; Ferreira, R; Ginja, M; Lopes, C; Oliveira, PA; Pinho-Oliveira, J; Rema, A; Soares-Maia, R; Talhada, D; Teixeira-Guedes, C1
Aliaga, C; Bruggeman, R; Calcagnotto, A; Cooper, TK; Das, A; El-Bayoumy, K; Liao, J; Manni, A; Prokopczyk, B; Richie, JP; Trushin, N; Washington, S; Xu, H1
Agullo, P; Arumugam, A; Boopalan, T; Gutierrez, C; Lopez, R; Nandy, S; Narayan, M; Rajkumar, L1
Jiang, W; Matthews, SB; McGinley, JN; Neil, ES; Thompson, HJ; Zhu, Z1
Brauer, HA; D'Arcy, M; Hamajima, N; Lampe, PD; Li, CI; Libby, TE; Thompson, HJ; Troester, MA; Yasui, YY1
Abdul Jalal, MI; Al-Astani Tengku Din, TA; Ariffin Wan Mansor, WN; Idris, FM; Jaafar, H; Shamsuddin, SH1
Emilia, ST; Shaari, R; Yaacob, NS; Yankuzo, HM1
Bojková, B; Ekmekcioglu, C; Fedoročko, P; Jäger, W; Jendželovský, R; Kajo, K; Kassayová, M; Kisková, T; Kokošová, N; Kubatka, P; Maier-Salamon, A; Mikeš, J; Orendáš, P; Papčová, Z; Rentsen, E; Svoboda, M; Thalhammer, T1
Adamicová, K; Adamkov, M; Bojková, B; Chmelová, M; Kajo, K; Kapinová, A; Kassayová, M; Kružliak, P; Kubatka, P; Orendáš, P; Péč, M; Sadloňová, V; Stollárová, N; Výbohová, D1
Barbisan, LF; Bidinotto, LT; Ciol, H; Fan, WY; Lopes, GA; Rodrigues, MA1
Arrazola, M; Carrera-González, MP; García, MJ; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ; Ruíz-Sanjuan, MD1
Bennett, C; Bernard, PS; Bode, AM; Green, JE; Grubbs, CJ; Juliana, MM; Lubet, RA; McGovern, R; Moeinpour, F; Reid, JM; Steele, VE; Stijleman, IJ; Thompson, MD1
Adamkov, M; Bojková, B; Dobrota, D; Kajo, K; Kapinová, A; Kassayová, M; Kello, M; Kruzliak, P; Kubatka, P; Mahmood, S; Mojžiš, J; Murin, R; Péč, M; Stollárová, N; Viera, T; Výbohová, D; Zulli, A1
Chen, Y; Dong, L; Long, J; Wang, Y; Zhang, F1
Cegielski, M; Dziegiel, P; Haus, D; Kobierzycki, C; Malicka, I; Paslawska, U; Podhorska-Okolow, M; Pula, B; Siewierska, K; Wozniewski, M1
Adamkov, M; Bálentová, S; Bojková, B; Demečková, V; Kajo, K; Kružliak, P; Kubatka, P; Orendáš, P; Péč, M; Výbohová, D; Zulli, A1
Faustino-Rocha, AI; Ferreira, R; Gama, A; Ginja, M; Oliveira, PA1
Abroun, S; Ashrafi, M; Azizian, M; Bathaie, SZ1
Boonyaphiphat, P; Deng, Y; Graidist, P; Lailerd, N; Nitiruangjarat, A; Sriwiriyajan, S; Tedasen, A1
Franklin, T; Sarkar, DK; Zhang, C1
Blanc, C; Bougnoux, P; Chauvin, L; Chevalier, S; Domingo, I; Goupille, C; Guimaraes, C; Mahéo, K; Pinault, M1
Choi, MR; Christov, K; Ivancic, D; Khan, SA; Lee, O1
Baretton, GB; Goerl, F; Louw, A; Macejová, D; Muders, M; Visser, K; Vollmer, G; Zierau, O1
Deng, Y; Graidist, P; Hiransai, P; Sriwiriyajan, S; Tedasen, A1
Nandakumar, K; Nayak, PG; Ramalingayya, GV; Rao, CM; Shenoy, RR1
Adamkov, M; Bobrov, N; Bomba, A; Demečková, V; Fedoročko, P; Jendželovský, R; Kassayová, M; Kisková, T; Kružliak, P; Kubatka, P; Orendáš, P; Strojný, L1
Ansari, MN; Devi, U; Gautam, S; Kaithwas, G; Manral, C; Rawat, JK; Roy, S; Saeedan, AS; Singh, M; Yadav, RK1
Cohick, WS; Globerman, SP; Saboya, M; Stires, H1
Calado, AM; Faustino-Rocha, AI; Ferreira, R; Gama, A; Ginja, M; Oliveira, PA1
Ansari, MN; Devi, U; Gautam, S; Kaithwas, G; Prakash, A; Rani, A; Rawat, JK; Roy, S; Saeedan, AS; Singh, M; Yadav, RK1
Blyth, BJ; Daino, K; Fukuda, M; Fukushi, M; Imaoka, T; Kakinuma, S; Kokubo, T; Morioka, T; Moriyama, H; Nishimura, M; Nishimura, Y; Shimada, Y; Showler, K; Takabatake, M1
Beumer, JH; Christner, SM; Davidson, NE; Hahm, ER; Kim, SH; Pore, SK; Roy, R; Samanta, SK; Sehrawat, A; Shuai, Y; Singh, KB; Singh, SV1
Bondarenko, NA; Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Poveshchenko, AF; Poveshchenko, OV; Raiter, TV; Strunkin, DN1
Ishchenko, IY; Kabakov, AV; Kazakov, OV; Konenkov, VI; Michurina, SV; Poveshchenko, AF; Raiter, TV; Strunkin, DN1
Arjmandi, BH; Hooshmand, S; Kamath, SK; Khalil, DA; Murillo, G; Singletary, K1
Cerar, A; Injac, R; Perse, M; Strukelj, B1
Canpinar, H; Esendagli, G; Guc, D; Guc, MO; Gunel-Ozcan, A; Yilmaz, G1
Fetisovova, Z; Kajo, K; Kubatka, P; Machalekova, K; Nosalova, G; Ostatnikova, D; Sadlonova, V1
Jiang, W; McGinley, JN; Thompson, HJ; Zhu, Z2
Adorini, L; Atalla, N; Buckley, B; Conney, AH; Lee, HJ; Lin, X; Lou, YR; Lu, G; Maehr, H; Paul, S; Suh, N; Thomas, PE; Uskokovic, M; Yang, I; Zheng, X1
Canpinar, G; Esendagli, G; Guc, D; Guc, MO; Gunel-Ozcan, A; Kansu, E; Yilmaz, G1
Boring, D; Grubbs, CJ; Juliana, MM; Lubet, RA; Ruppert, JM; Steele, VE1
Boppart, SA; Chaney, EJ; Oldenburg, AL; Rezaeipoor, R1
Adamicova, K; Kajo, K; Kubatka, P; Nosalova, G; Ostatnikova, D; Sadlonova, J; Sadlonova, V1
Ahlers, I; Ahlersova, E; Bojkova, B; Kajo, K; Kassayova, M; Kubatka, P; Orendas, P; Pec, M1
Ahlers, I; Ahlersova, E; Bojkova, B; Garajova, M; Kassayova, M; Kutna, V; Orendas, P1
Jiang, W; Thompson, HJ; Zhu, Z7
Jaafar, H; Mohamad Idris, F; Mohd Nafi, SN1
DeCastro, A; Ju, J; Lee, HJ; Lee, MJ; Newmark, HL; Paul, S; Smolarek, A; So, JY; Suh, N; Yang, CS1
Maffini, MV; Murray, TJ; Sonnenschein, C; Soto, AM; Ucci, AA1
Cho, YM; Hasumura, M; Hirose, M; Imai, T; Nishikawa, A; Ushijima, T; Watanabe, N1
McGinley, JN; Stushnoff, C; Thompson, HJ; Thompson, MD1
Boring, D; Grubbs, CJ; Juliana, MM; Kopelovich, L; Lubet, RA; Patlolla, J; Rao, CV; Steele, VE; Zhang, Y1
Archer, MC; McNamara, E1
McPhail, LD; Robinson, SP1
Del Pilar Carrera, M; García, MJ; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ2
Aliaga, C; Bruggeman, R; Calcagnotto, A; Cooper, T; El-Bayoumy, K; Manni, A; Mauger, D; Prokopczyk, B; Richie, JP; Trushin, N; Verderame, MF; Washington, S; Xu, H1
Jiang, W; Mann, PB; McTiernan, A; Thompson, HJ; Wolfe, P; Zhu, Z1
Choi, MS; Ha, YL; Islam, MA; Kim, GS; Kim, HG; Kim, JO; Kim, YS; Oh, TW; Won, CK1
Kassayová, M; Vaško, L; Vašková, J1
Arumugam, A; Castillo, R; de la Torre, A; Elsayed, A; Hernandez, C; Kotkowski, E; Rajkumar, L; Schecter, S1
Kokare, DM; Kotwal, SD; Nakhate, KT; Singru, PS; Subhedar, NK; Taksande, AG1
Jiang, W; McTiernan, A; Thompson, HJ; Wolfe, P; Zhu, Z1
Esendagli, G; Fahmi, T; Guc, D; Kansu, E; Yilmaz, G1
Evans, EM; Layman, DK; Moulton, CJ; Thorpe, MP; Valentine, RJ; Wagoner Johnson, AJ1
Benalcazar, WA; Boppart, SA; Chaney, EJ; Chowdary, PD; Gruebele, M; Jiang, Z; Marks, DL1
Iizuka, D; Imaoka, T; Nishimura, M; Nishimura, Y; Ohmachi, Y; Shimada, Y1
Crowell, JA; De Flora, SL; Grubbs, CJ; Heckman, BM; Juliana, MM; Lubet, RA; Steele, VE1
Bougnoux, P; Hajjaji, N; Schubnel, V1
Ahlers, I; Ahlersová, E; Bojková, B; Garajová, M; Kajo, K; Kassayová, M; Kisková, T; Kubatka, P; Mokáň, M; Orendáš, P; Péč, M1
El Bayoumy, K; Jiang, W; Manni, A; McGinley, JN; Prokopczyk, B; Richie, JP; Thompson, HJ; Zhu, Z1
Gediya, LK; Godbole, AM; Goss, PE; Hu, H; Njar, VC; Purushottamachar, P; Qi, S1
Brtko, J; Jakubíková, L; Liška, J; Macejová, D; Mlynarčíková, A; Ondková, S; Scsuková, S1
Gould, MN; Haag, JD; Mau, B; Samuelson, DJ; Sharma, D; Smits, BM; Woditschka, S1
Aliaga, C; Bruggeman, R; Calcagnotto, A; Cooper, TK; Das, A; Dickinson, R; El-Bayoumy, K; Liao, J; Manni, A; Prokopczyk, B; Richie, JP; Trushin, N; Verderame, MF; Washington, S; Xu, H1
Bhatia, S; Brueggemann, S; Cheng, B; Coburn, MA; Kleiner-Hancock, HE; Li, BD; Li, XL; Luraguiz, N; Mathis, JM; Maxuitenko, YY; Orchard, EA; Stoff-Khalili, MA; Zhang, S1
Kanematsu, S; Kuwata, M; Lai, YC; Tsubura, A; Yoshizawa, K; Yuri, T1
Eichelberg, MR; Gould, MN; Haag, JD; Meilahn, AL; Muelbl, MJ; Sharma, D; Smits, BM1
Bobrov, N; Bojková, B; Ekmekcioglu, C; Garajová, M; Jäger, W; Kassayová, M; Kisková, T; Orendáš, P; Thalhammer, T1
Jiang, W; McGinley, JN; Neil, ES; Thompson, HJ; Zacher, JH; Zhu, Z1
Brtko, J; Liska, J; Macejova, D; Ondkova, S1
Arumugam, A; Parada, J; Rajkumar, L1
Bojkova, B; Kajo, K; Karsnakova, R; Kassayova, M; Kiskova, T; Kubatka, P; Nosal, V; Orendas, P; Pec, M; Stollarova, N; Zihlavnikova, K1
Besson, P; Bougnoux, P; Hajjaji, N1
El Bayoumy, K; Jiang, W; Manni, A; McGinley, JN; Thompson, HJ; Zhu, Z1
Berger, MR; Dineva, IK; Eibl, H; Konstantinov, SM; Zaharieva, MM1
Bisht, S; Chenna, V; Chun, YS; de Wilde, RF; Hong, SM; Huso, DL; Maitra, A; Pramanik, D; Rudek, MA; Stearns, V; Sukumar, S; Yoshida, T; Zhang, Z; Zhao, M1
Andrei, S; Catoi, C; Cernea, C; Gal, AF; Taulescu, M1
Prendergast, BJ; Pyter, LM1
Aliaga, C; Bidinotto, LT; de Cicco, RL; El-Bayoumy, K; Manni, A; Russo, IH; Russo, J; Santucci-Pereira, J; Vanden Heuvel, JP; Vanegas, JE; Washington, S; Xu, H1
Ahlers, I; Ahlersová, E; Bojková, B; Kalická, K; Kubatka, P; Péč, M1
Bahadir, GM; Berna, T; Berrak, Y; Can, E; Handan, K; Ipek, E; Umit, UM1
Woo, W; Xu, Z2
Fukamachi, K; Han, BS; Maeda, M; Ohnishi, T; Takasuka, N; Tsuda, H; Yamasaki, T1
Murugesan, S; Noronha, OP; Samuel, AM; Shetty, SJ; Srivastava, TS1
Farris, MR; Glasebrook, AL; Grese, TA; Heyman, RA; Lamph, WW; Palkowitz, AD; Risingsong, R; Sporn, MB; Suh, N; Williams, CR1
Angioni, E; Banni, S; Carta, G; Dong, Y; Ip, C; Ip, MM; Melis, MP; Murru, E; Saebo, A; Spada, S1
Anderson, AS; Eto, I; Grizzle, WE; Grubbs, CJ; Johanning, GL; Rodríguez-Burford, C; Steele, VE; Stockard, CR; Weiss, HL1
Kang, JK1
Chan, FL; Chen, ZY; Cheung, SY; Choi, HL; Huang, Y; James, AE1
Bergoc, R; Cocca, C; Cricco, G; Croci, M; Gutiérrez, A; Martín, G; Núñez, M; Rivera, E1
Christov, K; Green, A; Grubbs, C; Ikui, A; Lubet, R; Shilkaitis, A; Steele, V; Weinstein, IB; Yao, R; You, M1
Chan, FL; Chen, S; Cheng, HK; Cheung, SY; Choi, HL; Huang, Y; Yuen, MT1
Choi, M; Hwang, SW; Kim, YI; Kotsopoulos, J; Martin, R; McKerlie, C; Medline, A; Renlund, R; Sohn, KJ1
Duminy, H; Kummer, A; Lee, R; Woo, W; Wu, B; Xu, Z1
Baranová, M; Brtko, J; Krammer, B; Macejová, D; Mostböck, S; Scheiblhofer, S; Thalhamer, J; Verwanger, T; Weiss, R1
Danbara, N; Fukunaga, K; Hada, T; Inoue, Y; Takada, H; Tsubura, A; Tsujita-Kyutoku, M; Yuri, T1
Blend, MJ; Dagar, S; Krishnadas, A; Onyüksel, H; Rubinstein, I1
Bougnoux, P; Denis, F; le Floch, O; Paon, L; Tranquart, F1
Dhanalakshmi, S; Mallikarjuna, GU; Raisuddin, S; Rao, AR1
Bougnoux, P; Chami, L; Colas, S; Denis, F; Le Floch, O; Louisot, P; Tranquart, F1
Allred, CD; Allred, KF; Clausen, LM; Doerge, DR; Helferich, WG; Ju, YH; Korol, DL; Schantz, SL; Wallig, MA1
Atigadda, VR; Beenken, SW; Bland, KI; Brouillette, WJ; Eto, I; Grubbs, CJ; Hill, DL; Lin, TH; Muccio, DD; Vines, KK1
Baranova, M; Brtko, J; Galbavy, S; Liska, J; Macejova, D; Mostbock, S; Scheiblhofer, S; Stvrtina, S; Thalhamer, J; Weiss, R; Zlatos, J1
Kankesan, J; Ling, V; Rajalakshmi, S; Rao, PM; Sarma, DS; Thiessen, JJ; Vanama, R; Yusuf, A1
Danbara, N; Nakane, Y; Pei, RJ; Sato, M; Tsubura, A; Yuri, T1
Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Kubatka, P; Luk, P; Marková, M1
Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Kubatka, P; Marková, M1
Badawi, AF; Badr, MZ; Eldeen, MB; Liu, Y; Ross, EA1
Bougnoux, P; Colas, S; Denis, F; Hoinard, C; Le Floch, O; Louisot, P; Ogilvie, G; Paon, L; Prat, M1
Calabro, JM; Maffini, MV; Sonnenschein, C; Soto, AM; Ucci, AA1
Anegón, I; Bausero, M; Hill, M; Khalife, J; Mazal, D; Ménoret, S; Osinaga, E1
Gilbert, P; Weaver, VM1
Danbara, N; Hatano, T; Nikaido, Y; Pei, RJ; Tsubura, A; Yoshizawa, K; Yuri, T1
Jang, DD; Jung, NJ; Kang, JS; Kim, DJ; Kim, S; Yang, KH1
Lee, S; Nimmo, M; Simpson, M; Xu, Z1
Guzman, R; Leong, H; Nandi, S; Ochoa, D; Rajkumar, L; Slusher, N; Talamantes, F; Thordarson, G1
Carrera, MP; García, MJ; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ; Valenzuela, MT1
Knott, KK; McGinley, JN; Spoelstra, NS; Thompson, HJ; Wolfe, P2
Bosland, MC; Horton, L; Lasano, S; Sherwood, OD; Steinetz, BG1
Jiang, W; McGinley, JN; Spoelstra, NS; Thompson, HJ; Wolfe, P; Zhu, Z1
Charbonneau, M; Cole, J; Desaulniers, D; Leingartner, K; Li, M; Musicki, B; Tsang, BK1
Che, JH; Jang, DD; Kang, JS; Kim, DJ; Kim, S; Nam, KT; Yang, KH1
Danbara, N; Hada, T; Shikata, N; Takada, H; Tsubura, A; Uehara, N1
Guzman, RC; Leong, H; Low, C; Nandi, S; Ochoa, D; Rajkumar, L; Semaan, S; Talamantes, F; Thordarson, G1
Barnes, S; Grubbs, C; Hall, P; Kim, H; Kirk, M; Prasain, JK; Smith, M1
Christov, K; Eto, I; Grubbs, CJ; Hursting, SD; Juliana, MM; Lubet, RA; Nunez, NP; Steele, VE1
Imaoka, T; Kakinuma, S; Maekawa, A; Nishimura, M; Nishimura, Y; Ootawara, M; Osada, H; Shimada, Y; Teramoto, A1
Gulati, A; Rai, A1
Arab, K; Bougnoux, P; Colas, S; Germain, E; Goupille, C; Maheo, K1
Kamiyama, Y; Okugawa, H; Sakaida, N; Tanaka, K; Tanano, A; Uemura, Y; Yamamoto, D1
Archer, MC; Hwang, SW; Kim, YI; Kotsopoulos, J; Lu, S; Martin, R; Medline, A; Renlund, R; Sohn, KJ1
Badger, TM; Chatman, L; Eason, RR; Geng, Y; Korourian, S; Simmen, RC; Till, SR; Velarde, MC1
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Archer, MC; Lee, WM; Lu, S; Medline, A1
McGinley, J; Singh, M; Thompson, HJ1
Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Cermáková, M; Kubatka, P; M ciková-Kalická, K; Mníchová-Chamilová, M1
Dagar, S; Onyüksel, H; Rubinstein, I; Sekosan, M1
Chochieva, AR; Dzhioev, FK1
Asamoto, M; Naito, A; Ochiya, T; Ota, T; Sekiya, T; Terada, M; Toriyama-Baba, H; Tsuda, H1
Anderson, MB; Blask, DE; Cheng, Q; Collins, A; Dai, J; Dwivedi, PD; Hill, SM; Kiefer, TL; Moroz, K; Myers, L; Spriggs, LL; Teplitzky, SR; Yuan, L1
Guzman, RC; Nandi, S; Talamantes, F; Thordarson, G; Van Horn, K1
Gay, J; Medina, D; Moraes, R; Peterson, LE1
Archer, MC; Chittim, BG; Desaulniers, D; Leingartner, K; Perkins, G; Russo, J; Wade, M; Yang, J1
Dagar, S; Lee, BS; Onyüksel, H; Rubinstein, I; Sekosan, M1
Guzman, RC; Nandi, S; Rajkumar, L; Talamantes, F; Thordarson, G; Yang, J1
Chen, WD; Gerson, SL; Lee, K; Liu, L; Markowitz, SD; Qin, X; Zhou, H1
Bhat, KP; Christov, K; Lantvit, D; Mehta, RG; Moon, RC; Pezzuto, JM1
Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Cermáková, M; Chamilová, M; Kalická, K; Kubatka, P1
Aliaga, C; Cohen, LA; Moyer, JD; Pittman, B; Wang, CX; Yu, L1
Chou, YC; Chu, O; Guzman, RC; Lee, AV; McCarty, M; Nandi, S; Talamantes, F; Thordarson, G; Van Horn, K; Yang, J1
Crist, KA; Grubbs, CJ; Hu, L; Johanning, GL; Lubet, RA; Wang, M; Wang, Y; Yao, R; You, M1
Conneely, O; Ginger, M; Hilsenbeck, SG; Medina, D; Omalle, BW; Rosen, J; Sivaraman, L1
Knott, KK; McGinley, JN; Thompson, HJ1
Asamoto, M; Hokaiwado, N; Naito, A; Ota, T; Toriyama-Baba, H; Tsuda, H1
Knott, KK; Lubet, RA; McGinley, JN; Steele, VE; Thompson, HJ1
Aldaz, CM; Ballenger, J; Davis, MF; El-Bayoumy, K; Li, JJ; Li, SA; Papa, D; Tawfik, O; Weroha, SJ1
Bigsby, RM1
Gould, MN; Griep, AE; Haag, JD; Lindstrom, MJ; Lohse, JK; Thompson, TA1
Anderson, MB; Bischoff, ED; Cheng, Q; Dai, J; Dwived, PD; Hill, SM; Kiefer, TL; Lai, L; Melancon, K; Moro, K; Nowfar, S; Teplitzky, SR; Yuan, L1
Bougnoux, P; Catroux, R; de Poncheville, L; Denis, F; Prat, M; Tranquart, F1
Swanson, SM; Unterman, TG1
Conneely, OM; Gay, J; Hilsenbeck, SG; Medina, D; O'Malley, BW; Shine, HD; Sivaraman, L1
Badamchian, M; Goldstein, AL; Moody, TW; Tuthill, C1
Archer, MC; Badawi, AF; El-Sohemy, A; Lu, S; Zhang, X1
Becci, PJ; Strum, JM1
Nandi, S; Richards, J1
Gullino, PM; Maiorana, A1
Peixoto de Menezes, A; Pinto da Silva, P1
Chan, PC; Rochefort, H; Vignon, F1
Becci, PJ; Brown, CC; Gander, RJ; Grubbs, CJ; Henderson, WR; Moon, RC; Mullen, LT; Newton, DL; Phillips, SL; Smith, JM; Sporn, MB; Thompson, HJ1
Cave, WT; Dunn, JT; MacLeod, RM2
Cox, R; Irving, CC1
Becci, PJ; Brown, CC; Moon, RC; Thompson, HJ1
Chan, PC; Cohen, LA; Head, JF; Wynder, EL1
Schabel, FM1
Pozharisskiĭ, KM1
Frankfurt, OS; Ostrovskaia, LA1
Goodman, DG; Grubbs, CJ; Moon, RC; Sporn, MB1
Neale, S; Parkin, R1
Maekawa, A; Odashima, S; Tada, K; Takeuchi, M1
Bots, GT; Willighagen, RG1
Ostrovskaia, LA; Vermel', EM1
Denlinger, RH; Koestner, A1
Chaudhuri, B; Chaudhuri, PK; Crist, KA; Shivaram, S1
Eto, I; Grubbs, CJ1
Ebert, K; Knuppen, R; Michna, H; Vollmer, G1
Guzman, RC; Hwang, SI; Miyamoto, S; Nandi, S; Osborn, RC; Sakthivel, R; Swanson, SM1
Adlakha, H; Singh, M; Thompson, HJ1
Arnold, W; Fichtner, I; Görlich, M; Hauff, P; Staab, HJ; Winterfeld, G2
Baggott, JE; Eto, I; Grubbs, CJ; Juliana, MM; Krumdieck, CL; Vaughn, WH1
Berger, MR; Eibl, H; Klenner, T; Reinhardt, M; Scherf, HR; Schmeiser, HH; Yanapirut, P1
Boylan, E; Cohen, LA; Epstein, M; Zang, E1
Archer, MC; Lu, SJ2
Archer, MC; Laroye, G; Lu, SJ1
Crowe, JP; Osborne, MP; Rosen, PP; Ruperto, JF; Telang, NT1
Charreau, EH; Lanari, C; Meiss, R; Pasqualini, CD; Pazos, P1
Babich, D; Bangert, JD; Dowlatshahi, K; Kluiber, R1
Archer, MC; Chaulk, EJ; Lu, SJ1
Berger, MR; Eibl, H; Kötting, J; Unger, C1
Berger, MR; Bunk, B; Klinga, K; Schmähl, D; Zhu, P1
Gould, MN; Haag, JD; Lindstrom, MJ1
Arts, CJ; Thijssen, JH; van den Berg, H1
Arts, CJ; Bunnik, GS; de Bie, AT; Thijssen, JH; van 't Veer, P; van den Berg, H1
Bevilacqua, G; Liotta, LA; Sobel, ME; Steeg, PS1
Cohen, LA; Kendall, ME; Meschter, C; Rose, DP; Zang, E1
Chander, SK; Coombes, RC; Evans, TR; Rowlands, MG1
Blask, DE; Grosso, DS; Hill, SM; Lemus-Wilson, A; Pelletier, DB; Wilson, ST; Wise, ME1
Beniashvili, DS; Bilanishvili, VG; Menabde, MZ1
Blair, WH; Hawrylewicz, EJ; Huang, HH1
Detrisac, CJ; Kelloff, GJ; Mehta, RG; Moon, RC; Ratko, TA1
Beniashvili, DSh; Bilanishvili, VG; Menabde, MZ1
Elson, CE; Gould, MN; Haag, JD; Kennan, WS; Tanner, MA1
Berger, MR; Garzon, F; Petru, E; Salas, M; Schmähl, D; Schwulera, U1
Ogawa, K; Sakai, H1
Bliss, JM; Coombes, RC; Dowsett, M; Easton, DF; Shah, P; Wilkinson, JR1
Isaacs, JT3
Eto, I; Grubbs, CJ; Juliana, MM; Whitaker, LM1
VanderPloeg, LC; Welsch, CW; Wolfrom, DM1
Chiodino, C; Ethier, SP; Jones, RF1
Chiasson, JC; Chiasson, JL; Lacroix, A; Srivastava, AK; Windisch, L1
Berger, MR; Reinhardt, M; Schmähl, D; Yanapirut, P1
Chander, SK; Coombes, RC; Dowsett, M; Jarman, M; Luqmani, Y; McCague, R; Newton, C1
Juzefyk, J; Kennedy, K; Thompson, HJ; Witt, M1
Anderson, CH; Beattie, CW; Han, MC; Hussain, RA1
Gould, MN; Haag, JD; Zhang, R2
Berger, MR; Bunk, B; Frei, E; Schmähl, D; Zhu, P1
Barbacid, M; Carney, WP; Garlick, DS; Hamer, PJ; Lavecchio, JA; Leav, I; Petit, D; Sukumar, S; Trimpe, KL1
Cohen, LA; Lau, YY; Ronai, Z1
Adlakha, H; Thompson, HJ1
Baluch, S; Coombes, RC; Griffiths, JR; Midwood, CJ; Stubbs, M1
Ichikawa, T; Isaacs, JT; Kyprianou, N1
Gould, MN; Hong, HJ; Hsu, LC1
Guzman, RC; Miyamoto, S; Nandi, S; Osborn, RC; Sukumar, S1
Barbacid, M; Kumar, R; Sukumar, S1
Badger, B; Demers, L; Lynch, J; Manni, A; Wright, C1
Hioki, K; Minoura, T; Sakaguchi, M; Takada, H; Takata, T; Yamamoto, M; Yamamura, M1
Aksoy, M; Berger, MR1
Banerjee, MR; Delp, CR; Treves, JS1
Berger, MR; Brix, HP; Eisenbrand, G; Schneider, MR; Tang, WC1
Kokoska, S; Urlwin, J1
Mikheev, AM1
Coombes, RC; Griffiths, JR; Gusterson, BA; Maxwell, RJ; Rodrigues, LM; Stubbs, M1
Fong, LY; Jensen, DE; Magee, PN1
Badger, B; Bartholomew, M; Demers, L; Herlyn, M; Manni, A; Masui, H; Mendelsohn, J; Wright, C1
Bernard, DJ; Chassagne, J; Chollet, P; Fonck, Y; Maurizis, JC; Plagne, R; Sauvezie, B1
Aksoy, M; Berger, MR; Beth, M; Schmähl, D3
Levin, MC; Santen, RJ; Santner, SJ1
Birt, DF; Bresnick, E; Markin, RS; Wheeler, M; Wolterman, K1
Berger, MR; Betsch, B; Brix, HP; Corr, R; Floride, JA; Schmähl, D1
Bhat, PV; Doskas, C; Lacroix, A1
Allen, WR; Armstrong, B; Bowman, M; Dulbecco, R1
Armstrong, B; Dulbecco, R1
Allen, R; Armstrong, B; Dulbecco, R1
Berger, MR; Klenner, T; Rao, NU; Schmähl, D; Sosnovsky, G; Wingen, F1
Bliss, JM; Borman, T; Coombes, RC; Schroeder, N; Shah, P; van der Meide, PH1
Dolezalová, V; Rejthar, A; Sugár, J; Tóth, J; Vermousek, I1
el Etreby, MF; Michna, H; Nishino, Y; Schneider, MR2
Hollister, JL; McCormick, DL; Spicer, AM1
Detrisac, CJ; Dinger, NM; Kelloff, GJ; Moon, RC; Ratko, TA; Thomas, CF1
Dinger, NM; Mehta, RG; Moon, RC; Nomides, CT; Pritchard, JF; Thomas, CF1
Dinger, NM; Dowlatshahi, K; Mehta, RG; Moon, RC; Thomas, CF1
Berger, MR; Kaufmann, M; Petru, E; Zeller, WJ2
Berger, U; Colston, KW; Coombes, RC1
Coombes, RC; Gusterson, BA; Monaghan, P; Rudland, PS; Williams, JC1
Anderson, CH; Beattie, CW; Braun, RJ; Pezzuto, JM1
Elson, CE; Gould, MN; Hurt, LM; Maltzman, TH; Tanner, MA1
Hawrylewicz, EJ; Madell, J; Moshovitis, CK; Reger, C1
Angres, G; Scherf, HR1
Bhat, PV; Lacroix, A1
Berger, MR; Eisenbrand, G; Klenner, T; Schmähl, D1
Bernard, DJ; Chassagne, J; Chollet, P; Maurizis, JC; Plagne, R1
Colston, K; Coombes, RC; Wilkinson, JR1
Klein, P; Klenner, T; Pool, BL; Schmähl, D; Wingen, F1
Baranao, L; Demers, L; Feil, P; Garcia, M; Manni, A; Rochefort, H; Wright, C1
Meeker, LD; Ritacco, KA; Ronan, AM; Thompson, HJ1
Dietrich, W; Görlich, M; Heise, E1
Barbacid, M1
Hammond, JM; Hsu, CJ; Manni, A; Wright, C1
Bruce, WR; Sharkey, SM1
Ronan, AM; Thompson, HJ1
Lee, SY; Rogers, AE1
Hawrylewicz, EJ1
Asch, BB; Bartley, JC; Guzman, RC; Imagawa, W; Nandi, S; Osborn, RC1
Jordan, VC1
Ahmed, SR; Badger, B; Demers, LM; Manni, A; Wright, C1
Cundiff, KC; Ethier, SP1
McCormick, DL; Spicer, AM1
Ahmed, SR; Badger, B; Luk, G; Manni, A; Santner, SJ; Wright, C1
Berger, MR; Schmähl, D1
Badger, B; Bartholomew, M; Demers, L; Manni, A; Wright, C1
Alvarez, E; Calaf, G; Jordan, C; Ramírez, G; Rodríguez, R1
Ahmed, SR; Badger, B; Bartholomew, M; Caplan, R; Luk, G; Manni, A; Rockette, H; Wright, C1
Gould, MN; Johnson, JA; Tanner, MA; Verma, AK1
Barbacid, M; Carney, WP; Sukumar, S1
Borsos, T; Glenn, GM; Szende, B; Yano, T; Zbar, B1
McCormick, DL1
Dietrich, W; Görlich, M; Heise, E; Helbing, D1
Demers, LM; English, HF; Lancaster, S; Manni, A1
Apostolov, K; Barker, W; Habib, NA; Hershman, MJ; Wood, CB1
Cleeve, HJ; Colston, KW; Hadcocks, L1
Berger, MR; Kaufmann, M; Petru, E1
Choi, KW; Cohen, LA; Wang, CX1
Guzman, RC; Miyamoto, S; Nandi, S; Osborn, RC1
Luo, XM; Wei, HJ; Yang, XP1
Blank, ME; Choi, K; Cohen, LA; Maeura, Y; Rose, DP; Thompson, DO1
Choi, K; Cohen, LA; Karmali, RA; Rose, DP; Thompson, DO1
Junker, JL; Pardue, RL; Shih, TY; Takahashi, K; Ward, JM; Weislow, OS1
Talmadge, JE1
Liotta, LA; Talmadge, JE; Thorgeirsson, UP; Turpeenniemi-Hujanen, T1
Chun, HG; Cradock, J; Davignon, P; Grieshaber, C; Hoth, D; Leyland-Jones, B; Moon, R; Rifkind, R; Shoemaker, D; Wolpert-DeFilippes, M1
Aksoy, M; Berger, MR; Schmähl, D2
Gottardis, MM; Jordan, VC1
Berger, MR; Petru, E; Schmähl, D1
Kokoska, SM1
Hawrylewicz, EJ; Huang, HH; Liu, JM1
Coombes, RC; Easton, D; Goss, PE; Singh, D; Wilkinson, JR; Williams, JC1
Aquino, T; Dorado, RD; Dytioco, S; Markell, N; Ooka, S; Porta, EA1
Demers, L; Luk, G; Manni, A; Wright, C1
Berger, MR; Habs, M; Petru, E; Schmähl, D1
Guillen, V; Hergueta, J; Lafarga, L; Lorenzo, HK; Pérez-López, FR; Urcia, MA1
Grantham, FH; Gullino, PM; Hill, DM; Pettigrew, HM1
Luo, XM; Wei, HJ; Yang, SP1
Farnell, DR; Grubbs, CJ; Hill, DL; McDonough, KC1
Herbst, EJ; Meeker, LD; Minocha, R; Ronan, AM; Thompson, HJ1
Berger, MR; Feichter, GE; Fink, M; Janetschek, P1
Bryan, GT; Ertürk, E; Tunca, JC1
Holtzman, S; Meade, M; Shellabarger, CJ; Stone, JP1
Berger, M; Prekajac, J; von Angerer, E1
Manni, A; Pontari, M; Wright, C1
Welsch, CW1
Lewko, WM; McConnell, KP1
Beattie, CW; Ratko, TA1
Meeker, LD; Roberts, JS; Tagliaferro, AR; Thompson, HJ1
Aksoy, M; Berger, MR; Frei, E1
Hiraki, S1

Reviews

27 review(s) available for methylnitrosourea and Experimental Mammary Neoplasms

ArticleYear
N-Methyl-N-nitrosourea as a mammary carcinogenic agent.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:12

    Topics: Animals; Breast; Carcinogens; Cell Transformation, Neoplastic; DNA; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea

2015
[Study of nutritional factors related to breast cancer prevention. Importance of animal models approaches].
    Archivos latinoamericanos de nutricion, 2005, Volume: 55, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carotenoids; Diet; Diet, Carbohydrate-Restricted; Disease Models, Animal; Energy Intake; Fatty Acids; Female; Glycine max; Iodine; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Rats; Retinoids; Risk Factors; Seaweed

2005
Selenium in carcinogenesis.
    Biochimica et biophysica acta, 1984, Volume: 738, Issue:4

    Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Cisplatin; Environmental Exposure; Epidemiologic Methods; Glutathione Peroxidase; Humans; Leukemia; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Neoplasms; Public Opinion; Selenium; United States

1984
Endocrine and cytostatic treatment of experimental mammary cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 71

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carmustine; Castration; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Ergolines; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Mice; Nitrosourea Compounds; Prednisolone; Rats; Tamoxifen; Vincristine

1980
Effect of exercise intensity and duration on the induction of mammary carcinogenesis.
    Cancer research, 1994, Apr-01, Volume: 54, Issue:7 Suppl

    Topics: Animals; Breast Neoplasms; Exercise; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms; Physical Conditioning, Animal; Rats; Risk Factors

1994
Animal models for breast cancer.
    Mutation research, 1995, Volume: 333, Issue:1-2

    Topics: Animals; Cyclin D1; Cyclins; Disease Models, Animal; Female; Gene Amplification; Genes, p53; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Oncogene Proteins; Rats

1995
Experimentally induced mammary tumors in rats.
    Breast cancer research and treatment, 1996, Volume: 39, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet; Disease Models, Animal; Disease Progression; Disease Susceptibility; Female; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Radiation-Induced; Rats; Rats, Inbred F344; Rats, Sprague-Dawley

1996
Intrinsic multidrug class 1 and 2 gene expression and localization in rat and human mammary tumors.
    Laboratory investigation; a journal of technical methods and pathology, 1996, Volume: 75, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Breast Neoplasms; Drug Resistance, Multiple; Female; Gene Expression; Humans; Immunologic Techniques; In Situ Hybridization; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Oligonucleotide Probes; Rats; RNA, Messenger; Staining and Labeling

1996
The use of transgenic animals in research.
    Environmental and molecular mutagenesis, 1998, Volume: 32, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Animals, Genetically Modified; Carcinogens, Environmental; Cell Transformation, Neoplastic; Codon; Genes, ras; Liver; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Knockout; Mitosis; Mutagenesis; Mutagenicity Tests; Mutagens; Neoplasms; Polymerase Chain Reaction; Rats; Sensitivity and Specificity; Transgenes

1998
Role of DNA repair in carcinogen-induced ras mutation.
    Mutation research, 2000, May-30, Volume: 450, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Animals, Genetically Modified; Base Sequence; Carcinogens; DNA; DNA Repair; Ethylnitrosourea; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Genetic; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Sprague-Dawley

2000
Atlas and histologic classification of tumors of the rat mammary gland.
    Journal of mammary gland biology and neoplasia, 2000, Volume: 5, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma, Intraductal, Noninfiltrating; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats

2000
Mechanisms of hormonal prevention of breast cancer.
    Annals of the New York Academy of Sciences, 2001, Volume: 952

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Breast Neoplasms; Cell Division; DNA Damage; Estradiol; Estrogens; Female; Gene Expression Profiling; Genes, p53; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Hormone-Dependent; Pregnancy; Progesterone; Rats; Rats, Inbred WF; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Reproductive History; Risk Factors

2001
Nitrosoureas: a review of experimental antitumor activity.
    Cancer treatment reports, 1976, Volume: 60, Issue:6

    Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Leukemia L1210; Lomustine; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Semustine

1976
[Successes of experimental oncology and problems of the study of the morphogenesis of tumors].
    Arkhiv patologii, 1975, Volume: 37, Issue:4

    Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Azoxymethane; Benzopyrenes; Brain Neoplasms; Carcinogens; Cricetinae; Dimethylhydrazines; Dogs; Esophageal Neoplasms; Ethionine; Ethylnitrosourea; Female; Hematopoietic System; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Nitrosoguanidines; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms

1975
Voluntary exercise and experimental mammary cancer.
    Advances in experimental medicine and biology, 1992, Volume: 322

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Volition

1992
Identification and characterization of differentially expressed genes in tumor metastasis: the nm23 gene.
    Basic life sciences, 1991, Volume: 57

    Topics: Animals; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Line, Transformed; Cell Transformation, Viral; DNA; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Melanoma, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Metastasis; Rats; Transfection; Tumor Cells, Cultured

1991
Mammary tumorigenesis.
    Progress in experimental tumor research, 1991, Volume: 33

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Cocarcinogenesis; Disease Models, Animal; Disease Susceptibility; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Precancerous Conditions

1991
Chemoprevention of mammary cancer by retinoids.
    Basic life sciences, 1990, Volume: 52

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Drug Synergism; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms, Hormone-Dependent; Organ Specificity; Rats; Retinoids; Skin Neoplasms; Species Specificity

1990
Oncogenes and human cancer: cause or consequence?
    Carcinogenesis, 1986, Volume: 7, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Chromosome Mapping; Gene Expression Regulation; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms; Neoplasms, Experimental; Oncogenes; Proto-Oncogenes; Rats; Retroviridae; Skin Neoplasms

1986
Chemically-induced mammary gland tumors in rats: modulation by dietary fat.
    Progress in clinical and biological research, 1986, Volume: 222

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Dietary Fats; DNA Replication; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats

1986
Fat-protein interaction, defined 2-generation studies.
    Progress in clinical and biological research, 1986, Volume: 222

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cell Transformation, Neoplastic; Cocarcinogenesis; Dietary Fats; Dietary Proteins; Disease Models, Animal; Eating; Epidemiologic Methods; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Thymidine

1986
Laboratory models of breast cancer to aid the elucidation of antiestrogen action.
    The Journal of laboratory and clinical medicine, 1987, Volume: 109, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Estrogen Antagonists; Estrogens; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Receptors, Estrogen; Structure-Activity Relationship

1987
[A study model of estrogens and antiestrogens analysis].
    Revista medica de Chile, 1987, Volume: 115, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Estrogen Antagonists; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Transplantation; Rats; Tamoxifen

1987
Preclinical approaches to the development of effective immunotherapeutic protocols for the treatment of metastasis.
    Progress in clinical and biological research, 1986, Volume: 212

    Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Immunotherapy; Interleukin-2; Killer Cells, Natural; Macrophage Activation; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Metastasis; Neoplasms, Radiation-Induced; Pyran Copolymer; Rats; Recombinant Proteins; Skin Neoplasms

1986
Expression of oncogenes in cancer metastases.
    Progress in clinical and biological research, 1986, Volume: 212

    Topics: Animals; Base Sequence; DNA, Neoplasm; Gene Amplification; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Oncogenes; Phenotype; Rats; RNA, Neoplasm; Transfection

1986
Hexamethylene bisacetamide: a polar-planar compound entering clinical trials as a differentiating agent.
    Cancer treatment reports, 1986, Volume: 70, Issue:8

    Topics: Acetamides; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cell Line; Cyclophosphamide; Dogs; Drug Evaluation, Preclinical; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms; Rats; Tumor Stem Cell Assay

1986
Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins.
    Cancer research, 1985, Volume: 45, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Animals; Antioxidants; Ascorbic Acid; Castration; Cocarcinogenesis; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Gonadal Steroid Hormones; Insulin; Male; Mammary Neoplasms, Experimental; Methylcholanthrene; Methylnitrosourea; Neoplasm Transplantation; Nucleotides, Cyclic; Pituitary Hormones, Anterior; Prostaglandins; Rats; Retinoids; Selenium; Thyroid Hormones; Vitamin E

1985

Trials

2 trial(s) available for methylnitrosourea and Experimental Mammary Neoplasms

ArticleYear
Effect of β-sitosterol against methyl nitrosourea-induced mammary gland carcinoma in albino rats.
    BMC complementary and alternative medicine, 2016, Jul-29, Volume: 16

    Topics: Animals; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Protective Agents; Rats; Rats, Wistar

2016
Preclinical approaches to the development of effective immunotherapeutic protocols for the treatment of metastasis.
    Progress in clinical and biological research, 1986, Volume: 212

    Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Immunotherapy; Interleukin-2; Killer Cells, Natural; Macrophage Activation; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Metastasis; Neoplasms, Radiation-Induced; Pyran Copolymer; Rats; Recombinant Proteins; Skin Neoplasms

1986

Other Studies

695 other study(ies) available for methylnitrosourea and Experimental Mammary Neoplasms

ArticleYear
Microemulsion for Prolonged Release of Fenretinide in the Mammary Tissue and Prevention of Breast Cancer Development.
    Molecular pharmaceutics, 2021, 09-06, Volume: 18, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cell Survival; Delayed-Action Preparations; Drug Liberation; Drug Screening Assays, Antitumor; Emulsions; Female; Fenretinide; Humans; Inhibitory Concentration 50; Mammary Glands, Animal; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Mice; Rats

2021
Copenhagen Rats Display Dominantly Inherited Yet Non-uniform Resistance to Spontaneous, Radiation-induced, and Chemically-induced Mammary Carcinogenesis.
    Anticancer research, 2022, Volume: 42, Issue:5

    Topics: Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2022
The Role of Cancer and Somatic Stem Cells in the Anti-Inflammatory and Antitumor Effects of Aconitum baicalense Extract on Experimental Breast Cancer.
    Bulletin of experimental biology and medicine, 2023, Volume: 175, Issue:2

    Topics: Aconitum; Adult Stem Cells; Animals; Anti-Inflammatory Agents; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Plant Extracts

2023
Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling.
    BMC cancer, 2019, Oct-24, Volume: 19, Issue:1

    Topics: Animals; Apoptosis; Carcinogenesis; Caspase 3; Caspase 8; Female; Heart Rate; Inflammation Mediators; Lipoxygenase; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitochondria; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Tadalafil

2019
Correlation Analysis of Morphological Changes of Structural and Functional Areas of Mesenteric Lymph Nodes with Cytokines of Lymph of Thoracic Lymphatic Duct in Experimental Breast Cancer.
    Bulletin of experimental biology and medicine, 2020, Volume: 168, Issue:4

    Topics: Animals; Chemokine CCL2; Chemokine CCL3; Chemokine CXCL1; Female; Gene Expression Regulation, Neoplastic; Interleukin-5; Interleukin-6; Lymph Nodes; Lymphatic Metastasis; Lymphocytes; Macrophage Colony-Stimulating Factor; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mesentery; Methylnitrosourea; Rats; Rats, Wistar; Thoracic Duct

2020
Correlation of the Levels of microRNA with Cell Composition of Axillary Lymph Node in Wistar Rats with Breast Cancer.
    Bulletin of experimental biology and medicine, 2020, Volume: 168, Issue:4

    Topics: Animals; Axilla; Cell Count; Female; Gene Expression Regulation, Neoplastic; Lymph Nodes; Lymphatic Metastasis; Lymphocytes; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; MicroRNAs; Rats; Rats, Wistar

2020
Morphological Study of Mesenteric Lymph Nodes in Rats with Experimental Breast Cancer Treated with Fragmented Double-Stranded DNA.
    Bulletin of experimental biology and medicine, 2020, Volume: 168, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; DNA; DNA Fragmentation; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mastectomy; Mesentery; Methotrexate; Methylnitrosourea; Rats; Rats, Wistar; Treatment Outcome

2020
Cytokines of the Lymph and Blood Serum as Markers of Oncogenesis and Efficiency of Therapy in Chemically Induced Breast Cancer in Wistar Rats.
    Bulletin of experimental biology and medicine, 2020, Volume: 168, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blood Chemical Analysis; Carcinogenesis; Combined Modality Therapy; Cytokines; Drug Monitoring; Female; Lymph; Mammary Neoplasms, Experimental; Mastectomy; Methylnitrosourea; Prognosis; Rats; Rats, Wistar; Treatment Outcome

2020
(-)-Kusunokinin inhibits breast cancer in N-nitrosomethylurea-induced mammary tumor rats.
    European journal of pharmacology, 2020, Sep-05, Volume: 882

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Female; Humans; Lignans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats, Sprague-Dawley

2020
Evaluation of NMU-Induced Breast Cancer Treated with Sirolimus and Sunitinib on Breast Cancer Growth.
    Asian Pacific journal of cancer prevention : APJCP, 2020, Oct-01, Volume: 21, Issue:10

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sirolimus; Sunitinib

2020
Cerium oxide nanoparticles elicit antitumourigenic effect in experimental breast cancer induced by N-methyl-N-nitrosourea and benzo(a)pyrene in female Wistar rats.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:4

    Topics: Animals; Antineoplastic Agents; Benzo(a)pyrene; Cerium; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nanoparticles; Rats; Rats, Wistar

2021
Vascular Endothelial Growth Factor Mediates the Sprouted Axonogenesis of Breast Cancer in Rat.
    The American journal of pathology, 2021, Volume: 191, Issue:3

    Topics: Alkylating Agents; Animals; Axons; Extracellular Signal-Regulated MAP Kinases; Female; Mammary Neoplasms, Experimental; MAP Kinase Signaling System; Methylnitrosourea; Neurites; Neurogenesis; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Vascular Endothelial Growth Factor A

2021
Effect of Voacamine upon inhibition of hypoxia induced fatty acid synthesis in a rat model of methyln-nitrosourea induced mammary gland carcinoma.
    BMC molecular and cell biology, 2021, Jun-05, Volume: 22, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Body Weight; Carcinoma; Computer Simulation; Electrocardiography; Fatty Acids; Female; Heart Rate; Hypoxia-Inducible Factor-Proline Dioxygenases; Ibogaine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Metabolome; Methylnitrosourea; Neovascularization, Pathologic; Rats, Wistar; Tamoxifen

2021
Chronic propranolol treatment moderately attenuated development of N-methyl-N-nitrosourea-induced mammary carcinoma in female rats.
    Anti-cancer drugs, 2021, 11-01, Volume: 32, Issue:10

    Topics: Adrenergic beta-Antagonists; Animals; Caspase 3; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenylethanolamine N-Methyltransferase; Propranolol; Proto-Oncogene Proteins c-fos; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tumor Microenvironment; Tyrosine 3-Monooxygenase

2021
Mast Cells in Mammary Carcinogenesis: Host or Tumor Supporters?
    Anticancer research, 2017, Volume: 37, Issue:3

    Topics: Animals; Cell Proliferation; Cell Transformation, Neoplastic; Female; Immunohistochemistry; Ketotifen; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mast Cells; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2017
Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis.
    Oncotarget, 2017, May-16, Volume: 8, Issue:20

    Topics: Animals; Cell Transformation, Neoplastic; Circadian Rhythm; Disease Models, Animal; DNA Repair; Female; Jet Lag Syndrome; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Period Circadian Proteins; Rats; Rats, Inbred F344; Sirtuin 1

2017
Effect of allyl isothiocyanate on NF-κB signaling in 7,12-dimethylbenz(a)anthracene and N-methyl-N-nitrosourea-induced mammary carcinogenesis.
    Breast cancer (Tokyo, Japan), 2018, Volume: 25, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Female; Food Preservatives; Gene Expression Regulation, Neoplastic; Isothiocyanates; Mammary Neoplasms, Experimental; Methylnitrosourea; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction

2018
Impact of Physical Training on Sex Hormones and Their Receptors During
    Anticancer research, 2017, Volume: 37, Issue:7

    Topics: Animals; Apoptosis; Carcinogenesis; Carcinogens; Estrogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Conditioning, Animal; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone

2017
Inherent aerobic capacity-dependent differences in breast carcinogenesis.
    Carcinogenesis, 2017, 09-01, Volume: 38, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Biomarkers, Tumor; Carcinogenesis; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Conditioning, Animal; Proto-Oncogene Proteins c-akt; Rats; Risk Factors; TOR Serine-Threonine Kinases

2017
Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 174

    Topics: Alkylating Agents; Animals; Cell Proliferation; Chalcones; Female; Flavanones; Humulus; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Ovariectomy; Plant Extracts; Rats, Sprague-Dawley; Rats, Wistar; Uterus

2017
Immunomodulatory effects of a bioactive fraction of Strobilanthes crispus in NMU-induced rat mammary tumor model.
    Journal of ethnopharmacology, 2018, Mar-01, Volume: 213

    Topics: Acanthaceae; Animals; Cytokines; Female; Immunologic Factors; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytotherapy; Plant Extracts; Plant Leaves; Rats, Sprague-Dawley; T-Lymphocytes; Tumor Burden

2018
Anterior Mediastinal Lymph Nodes in Chemically Induced Breast Cancer.
    Bulletin of experimental biology and medicine, 2017, Volume: 164, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cell Proliferation; Cyclophosphamide; Female; Fluorouracil; Injections, Subcutaneous; Lymph Nodes; Lymphatic Metastasis; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mediastinum; Methotrexate; Methylnitrosourea; Plasma Cells; Rats; Rats, Wistar; T-Lymphocytes

2017
Cellular and Molecular Changes in MNU-Induced Breast Tumours Injected with PF4 or bFGF
    Asian Pacific journal of cancer prevention : APJCP, 2017, Dec-28, Volume: 18, Issue:12

    Topics: Alkylating Agents; Angiogenesis Inhibitors; Animals; Female; Fibroblast Growth Factor 2; Injections, Intralesional; Mammary Neoplasms, Experimental; Methylnitrosourea; Neovascularization, Pathologic; Platelet Factor 4; Rats; Rats, Sprague-Dawley

2017
Suppressive effects of capsaicin against N-nitrosomethylurea-induced mammary tumorigenesis in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 98

    Topics: Animals; Antioxidants; Capsaicin; Carcinogenesis; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley

2018
Nocturnal resveratrol administration inhibits chemically induced breast cancer formation in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2017, Volume: 68, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cytokines; Drug Administration Schedule; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Period Circadian Proteins; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Burden

2017
Inhibitory Effect of Filipendula ulmaria on Mammary Carcinogenesis Induced by Local Administration of Methylnitrosourea to Target Organ in Rats.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:8

    Topics: Animals; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Filipendula; Flavonoids; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Structure; Phenols; Plant Extracts; Rats; Rats, Wistar; Structure-Activity Relationship; Tannins

2018
Effects of phenidone (DuCLOX-2/5 inhibitor) against N-methyl-N-nitrosourea induced mammary gland carcinoma in albino rats.
    Toxicology and applied pharmacology, 2018, 07-15, Volume: 351

    Topics: Animals; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2 Inhibitors; Female; Lipoxygenase Inhibitors; Mammary Neoplasms, Experimental; Methylnitrosourea; Pyrazoles; Random Allocation; Rats; Rats, Wistar; Treatment Outcome

2018
ALA-mediated biphasic downregulation of α-7nAchR/HIF-1α along with mitochondrial stress modulation strategy in mammary gland chemoprevention.
    Journal of cellular physiology, 2019, Volume: 234, Issue:4

    Topics: Acetylcholine; Acetylcholinesterase; alpha-Linolenic Acid; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anticarcinogenic Agents; Apoptosis; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Metabolism; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitochondria; Oxidative Stress; Rats, Wistar; Signal Transduction

2019
Comparison of Effects of Diet on Mammary Cancer: Efficacy of Various Preventive Agents and Metabolomic Changes of Different Diets and Agents.
    Cancer prevention research (Philadelphia, Pa.), 2018, Volume: 11, Issue:12

    Topics: Animals; Antineoplastic Agents; Diet, High-Fat; Female; Food-Drug Interactions; Mammary Neoplasms, Experimental; Metabolomics; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Time Factors; Treatment Outcome

2018
Effect of Neoadjuvant and Adjuvant Therapy of Experimental Breast Cancer on the Structure of Mesenteric Lymph Nodes.
    Bulletin of experimental biology and medicine, 2018, Volume: 166, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Lymph Nodes; Lymphocyte Subsets; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mast Cells; Mesentery; Methotrexate; Methylnitrosourea; Neoadjuvant Therapy; Neutrophils; Rats; Rats, Wistar

2018
Root bark extract of Calliandra portoricensis (Jacq.) Benth. chemoprevents N-methyl-N-nitrosourea-induced mammary gland toxicity in rats.
    Journal of ethnopharmacology, 2019, Apr-06, Volume: 233

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Catalase; Chemoprevention; Fabaceae; Female; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Mammary Neoplasms, Experimental; Methylnitrosourea; Plant Extracts; Plant Roots; Rats, Wistar; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone

2019
Metformin and melatonin improve histopathological outcome of NMU-induced mammary tumors in rats.
    Pathology, research and practice, 2019, Volume: 215, Issue:4

    Topics: Animals; Cell Proliferation; Diet, High-Fat; Female; Mammary Neoplasms, Experimental; Melatonin; Metformin; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2019
Anti-Estrogenic and Anti-Cell Proliferative Effect of Allyl Isothiocyanate in Chemoprevention of Chemically Induced Mammary Carcinogenesis in Rats.
    Pathology oncology research : POR, 2020, Volume: 26, Issue:2

    Topics: Animals; Anthracenes; Carcinogens; Cell Proliferation; Chemoprevention; Estrogen Receptor Modulators; Female; Isothiocyanates; Mammary Neoplasms, Experimental; Methylnitrosourea; Piperidines; Rats; Rats, Sprague-Dawley

2020
Effect of an extract of Withania somnifera root on estrogen receptor-positive mammary carcinomas.
    Anticancer research, 2013, Volume: 33, Issue:4

    Topics: Alkylating Agents; Animals; Dose-Response Relationship, Drug; Female; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Withania

2013
Estimation of rat mammary tumor volume using caliper and ultrasonography measurements.
    Lab animal, 2013, Volume: 42, Issue:6

    Topics: Animals; Female; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Examination; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tumor Burden; Ultrasonography

2013
Maternal dietary canola oil suppresses growth of mammary carcinogenesis in female rat offspring.
    Nutrition and cancer, 2013, Volume: 65, Issue:5

    Topics: Animals; Body Weight; Carcinogenesis; Diet; Dietary Fats; Disease Models, Animal; Fatty Acids, Monounsaturated; Female; Lactation; Mammary Neoplasms, Experimental; Maternal Nutritional Physiological Phenomena; Methylnitrosourea; Pregnancy; Rapeseed Oil; Rats; Rats, Sprague-Dawley

2013
Proteomic changes induced by effective chemopreventive ratios of n-3:n-6 fatty acids and tamoxifen against MNU-induced mammary cancer in the rat.
    Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:9

    Topics: Alkylating Agents; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Diet; Fatty Acids, Omega-6; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tamoxifen

2013
Ultrasonographic, thermographic and histologic evaluation of MNU-induced mammary tumors in female Sprague-Dawley rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2013, Volume: 67, Issue:8

    Topics: Animals; Female; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Thermography; Ultrasonography

2013
Upregulated Myc expression in N-methyl nitrosourea (MNU)- induced rat mammary tumours.
    Asian Pacific journal of cancer prevention : APJCP, 2013, Volume: 14, Issue:8

    Topics: Animals; Carcinogens; Female; Gene Expression Regulation, Neoplastic; Glyceraldehyde-3-Phosphate Dehydrogenases; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation

2013
mTORC1/2 targeted by n-3 polyunsaturated fatty acids in the prevention of mammary tumorigenesis and tumor progression.
    Oncogene, 2014, Sep-11, Volume: 33, Issue:37

    Topics: Animals; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Disease Progression; Fatty Acids, Omega-3; Female; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Methylnitrosourea; Mice; Mice, Nude; Mice, SCID; Multiprotein Complexes; Neoplasm Transplantation; Neovascularization, Pathologic; Rats; Signal Transduction; TOR Serine-Threonine Kinases

2014
MNU-induced rat mammary carcinomas: immunohistology and estrogen receptor expression.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2013, Volume: 32, Issue:2

    Topics: Actins; Adenocarcinoma; Animals; Carcinogens; Cell Differentiation; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Estrogen

2013
Influence of omega-3 fatty acids on Tamoxifen-induced suppression of rat mammary carcinogenesis.
    International journal of cancer, 2014, Apr-01, Volume: 134, Issue:7

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinogenesis; Chemoprevention; Diet; Fatty Acids, Omega-3; Female; Fish Oils; Ki-67 Antigen; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Tamoxifen

2014
Neem leaf extract inhibits mammary carcinogenesis by altering cell proliferation, apoptosis, and angiogenesis.
    Cancer biology & therapy, 2014, Volume: 15, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azadirachta; Carcinogenesis; Cell Proliferation; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley

2014
Excess weight gain accelerates 1-methyl-1-nitrosourea-induced mammary carcinogenesis in a rat model of premenopausal breast cancer.
    Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:3

    Topics: Animals; Carcinogenesis; Carcinogens; Diet; Disease Models, Animal; Disease Susceptibility; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Obesity; Premenopause; Rats; Rats, Sprague-Dawley; Weight Gain

2014
Dermcidin expression is associated with disease progression and survival among breast cancer patients.
    Breast cancer research and treatment, 2014, Volume: 144, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Animals; Biomarkers, Tumor; Breast Neoplasms; Dermcidins; Disease Progression; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Middle Aged; Random Allocation; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Rapamycin and PF4 induce apoptosis by upregulating Bax and down-regulating survivin in MNU-induced breast cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:9

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Transformation, Neoplastic; Down-Regulation; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Microtubule-Associated Proteins; Platelet Factor 4; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; Survivin; Transcriptional Activation; Up-Regulation

2014
Correlation of tumour response with starting tumour size and dose of tamoxifen in an N-methyl-N-nitrosourea (NMU)-induced rat mammary cancer model.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:16

    Topics: Animals; Body Weight; Creatinine; Drug Dosage Calculations; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Random Allocation; Rats; Rats, Sprague-Dawley; Tamoxifen; Treatment Outcome; Tumor Burden; Urea

2014
Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2014, Volume: 23, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Carcinogens; Celecoxib; Chemoprevention; Drug Synergism; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Pyrazoles; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfonamides

2014
Melatonin potentiates the anti-tumour effect of pravastatin in rat mammary gland carcinoma model.
    International journal of experimental pathology, 2014, Volume: 95, Issue:6

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Carcinoma in Situ; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Disease Models, Animal; Drug Synergism; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Pravastatin; Rats, Sprague-Dawley

2014
Maternal western style diet increases susceptibility to chemically-induced mammary carcinogenesis in female rats offspring.
    Nutrition and cancer, 2014, Volume: 66, Issue:8

    Topics: Animals; Apoptosis; Carcinogenesis; Caspase 3; Cell Differentiation; Cell Proliferation; Diet, Western; Disease Susceptibility; Estrogen Receptor alpha; Female; Mammary Neoplasms, Experimental; Maternal Nutritional Physiological Phenomena; Methylnitrosourea; Pregnancy; Rats; Rats, Sprague-Dawley

2014
Normolipidic dietary fat modifies circulating Renin-Angiotensin system-regulating aminopeptidase activities in rat with breast cancer.
    Integrative cancer therapies, 2015, Volume: 14, Issue:2

    Topics: Aminopeptidases; Animals; Dietary Fats; Female; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Oleic Acid; Olive Oil; Plant Oils; Rats; Rats, Wistar; Renin-Angiotensin System; Sunflower Oil

2015
Lack of effect of metformin on mammary carcinogenesis in nondiabetic rat and mouse models.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:3

    Topics: Alkylating Agents; Animals; Biomarkers, Tumor; Disease Models, Animal; Female; Humans; Hypoglycemic Agents; Mammary Neoplasms, Experimental; Metformin; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, SCID; Mice, Transgenic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution; Tumor Cells, Cultured

2015
Fruit peel polyphenols demonstrate substantial anti-tumour effects in the model of breast cancer.
    European journal of nutrition, 2016, Volume: 55, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Proliferation; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Female; Flavonoids; Fruit; Humans; Ki-67 Antigen; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Polyphenols; Rats; Stilbenes; Tyrosine; Vascular Endothelial Growth Factor Receptor-2

2016
Dietary fatty acids affect lipid metabolism and estrogen receptor expression in N-methyl-N-nitrosourea-induced rat mammary cancer model.
    Clinical laboratory, 2015, Volume: 61, Issue:3-4

    Topics: Animals; CD36 Antigens; Diet; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Fatty Acid Synthases; Fatty Acid-Binding Proteins; Fatty Acids; Fatty Acids, Unsaturated; Female; Immunohistochemistry; Lipid Metabolism; Mammary Neoplasms, Experimental; Methylnitrosourea; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Estrogen

2015
The effect of physical training on the N-methyl-N-nitrosourea-induced mammary carcinogenesis of Sprague-Dawley rats.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:11

    Topics: Animals; Apoptosis; Carcinogens; Cell Proliferation; Female; Immunohistochemistry; In Situ Nick-End Labeling; Ki-67 Antigen; Mammary Neoplasms, Experimental; Methylnitrosourea; Microarray Analysis; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley

2015
Role of high-fat diet on the effect of pioglitazone and melatonin in a rat model of breast cancer.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2016, Volume: 25, Issue:5

    Topics: Animals; Antioxidants; Carcinogens; Diet, High-Fat; Disease Models, Animal; Drug Therapy, Combination; Female; Hypoglycemic Agents; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Pioglitazone; Rats; Rats, Sprague-Dawley; Thiazolidinediones

2016
Effect of Crocin on Cell Cycle Regulators in N-Nitroso-N-Methylurea-Induced Breast Cancer in Rats.
    DNA and cell biology, 2015, Volume: 34, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carotenoids; Cell Cycle; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Female; Gene Expression Regulation, Neoplastic; Genes, p53; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats, Wistar

2015
Anticancer and Cancer Prevention Effects of Piperine-Free Piper nigrum Extract on N-nitrosomethylurea-Induced Mammary Tumorigenesis in Rats.
    Cancer prevention research (Philadelphia, Pa.), 2016, Volume: 9, Issue:1

    Topics: Alkaloids; Animals; Anticarcinogenic Agents; Apoptosis; Benzodioxoles; Body Weight; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Mice; Mice, Inbred ICR; Piper nigrum; Piperidines; Plant Extracts; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley

2016
Inhibition of Mammary Cancer Progression in Fetal Alcohol Exposed Rats by β-Endorphin Neurons.
    Alcoholism, clinical and experimental research, 2016, Volume: 40, Issue:1

    Topics: Alkylating Agents; Animals; beta-Endorphin; Bucladesine; Central Nervous System Depressants; Cytokines; Disease Progression; Disease Susceptibility; Epinephrine; Ethanol; Female; Granzymes; Hypothalamus; Interferon-gamma; Mammary Neoplasms, Experimental; Methylnitrosourea; Neurons; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction

2016
Long chain n-3 polyunsaturated fatty acids increase the efficacy of docetaxel in mammary cancer cells by downregulating Akt and PKCε/δ-induced ERK pathways.
    Biochimica et biophysica acta, 2016, Volume: 1861, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorylation; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Taxoids; Time Factors; Transfection; Tumor Burden

2016
Progesterone receptor antagonism inhibits progestogen-related carcinogenesis and suppresses tumor cell proliferation.
    Cancer letters, 2016, 07-01, Volume: 376, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antigens, CD34; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Methylnitrosourea; Mice; Mifepristone; Neovascularization, Pathologic; Norpregnadienes; Progesterone; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone; Time Factors

2016
The phytoestrogenic Cyclopia extract, SM6Met, increases median tumor free survival and reduces tumor mass and volume in chemically induced rat mammary gland carcinogenesis.
    The Journal of steroid biochemistry and molecular biology, 2016, Volume: 163

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cyclopia Plant; Estrogen Antagonists; Female; G1 Phase Cell Cycle Checkpoints; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytoestrogens; Rats; Receptors, Estrogen; Survival Analysis; Tamoxifen; Tumor Burden

2016
Anti-cancer effects of Piper nigrum via inducing multiple molecular signaling in vivo and in vitro.
    Journal of ethnopharmacology, 2016, Jul-21, Volume: 188

    Topics: Angiogenic Proteins; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Breast Neoplasms; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Neoplasm Invasiveness; Neovascularization, Pathologic; Oxidative Stress; Phytotherapy; Piper nigrum; Plant Extracts; Plants, Medicinal; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Time Factors

2016
Female rats induced with mammary cancer as a relevant animal model for doxorubicin-induced chemobrain in vivo.
    Clinical and experimental pharmacology & physiology, 2016, Volume: 43, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Carcinogens; Cognition; Disease Models, Animal; Doxorubicin; Female; Humans; Mammary Neoplasms, Experimental; Memory Disorders; Memory, Episodic; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2016
Anticancer and Immunomodulatory Effects of Lactobacillus plantarum LS/07, Inulin and Melatonin in NMU-induced Rat Model of Breast Cancer.
    Anticancer research, 2016, Volume: 36, Issue:6

    Topics: Animals; Antineoplastic Agents; Female; Immunologic Factors; Interleukin-6; Inulin; Lactobacillus plantarum; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Probiotics; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1

2016
Peroral Estradiol Is Sufficient to Induce Carcinogen-Induced Mammary Tumorigenesis in Ovariectomized Rats without Progesterone.
    PloS one, 2016, Volume: 11, Issue:9

    Topics: Animals; Body Weight; Carcinogenesis; Carcinogens; Cell Proliferation; Estradiol; Female; Immunohistochemistry; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Ovariectomy; Progesterone; Rats, Sprague-Dawley; Time Factors; Uterus

2016
Electron Microscopy Findings in N-Methyl-N-Nitrosourea-Induced Mammary Tumors.
    Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, 2016, Volume: 22, Issue:5

    Topics: Animals; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Microscopy, Electron, Transmission; Rats; Rats, Sprague-Dawley

2016
α-Chymotrypsin regulates free fatty acids and UCHL-1 to ameliorate N-methyl nitrosourea induced mammary gland carcinoma in albino wistar rats.
    Inflammopharmacology, 2016, Volume: 24, Issue:5

    Topics: Animals; Cattle; Chymotrypsin; Fatty Acids, Nonesterified; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Oxidative Stress; Rats; Rats, Wistar; Ubiquitin Thiolesterase

2016
Analysis of genes involved in the PI3K/Akt pathway in radiation- and MNU-induced rat mammary carcinomas.
    Journal of radiation research, 2017, Mar-01, Volume: 58, Issue:2

    Topics: Animals; Base Sequence; Female; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation, Missense; Nitrosourea Compounds; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Radiation, Ionizing; Rats, Sprague-Dawley; Sequence Deletion; Signal Transduction

2017
Disease Subtype-Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A.
    Journal of the National Cancer Institute, 2017, Volume: 109, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetyl Coenzyme A; Aldehyde Dehydrogenase 1 Family; Animals; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle; Cytokines; Deoxyguanosine; Electron Transport Complex III; Female; Forkhead Transcription Factors; Humans; Ki-67 Antigen; Lactic Acid; Leptin; Malates; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; MCF-7 Cells; Methylnitrosourea; Mice; Mitosis; Mitotic Index; Rats; Receptors, Estrogen; Retinal Dehydrogenase; Retroviridae Infections; Signal Transduction; Tumor Burden; Tumor Virus Infections; Withanolides

2017
Levels of miRNA and Hormones in Thoracic Duct Lymph in Rats with Experimental Breast Cancer Induced by N-Methyl-N-Nitrosourea.
    Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cyclophosphamide; Estradiol; Female; Fluorouracil; Follicle Stimulating Hormone; Luteinizing Hormone; Lymph; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; MicroRNAs; Prolactin; Rats; Rats, Wistar; Thoracic Duct; Thyroglobulin

2017
The Thymus in Experimental Mammary Carcinogenesis and Polychemotherapy.
    Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Cyclophosphamide; Epithelial Cells; Female; Fluorouracil; Injections, Intraperitoneal; Lymphocytes; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Rats, Wistar; Thymus Gland; Thymus Neoplasms

2017
The combination of genistin and ipriflavone prevents mammary tumorigenesis and modulates lipid profile.
    Clinical nutrition (Edinburgh, Scotland), 2008, Volume: 27, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Isoflavones; Lipid Metabolism; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2008
N-methylnitrosourea induced breast cancer in rat, the histopathology of the resulting tumours and its drawbacks as a model.
    Pathology oncology research : POR, 2009, Volume: 15, Issue:1

    Topics: Animals; Carcinogens; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Invasiveness; Rats; Rats, Sprague-Dawley

2009
Coexistence of different tissue tumourigenesis in an N-methyl-N-nitrosourea-induced mammary carcinoma model: a histopathological report in Sprague-Dawley rats.
    Laboratory animals, 2009, Volume: 43, Issue:1

    Topics: Animals; Carcinoma, Ductal, Breast; Diagnosis, Differential; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Multiple Primary; Rats; Rats, Sprague-Dawley

2009
Neoplastic effects of exemestane in premenopausal breast cancer model.
    Neoplasma, 2008, Volume: 55, Issue:6

    Topics: Androstadienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Body Weight; Drug Evaluation, Preclinical; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Premenopause; Rats; Rats, Sprague-Dawley

2008
Energetics and mammary carcinogenesis: effects of moderate-intensity running and energy intake on cellular processes and molecular mechanisms in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:3

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Caloric Restriction; Caspase 3; Cell Cycle; Energy Metabolism; Female; Fluorescent Antibody Technique, Indirect; Immunoenzyme Techniques; Ki-67 Antigen; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Motor Activity; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Running

2009
Gemini vitamin D analogues inhibit estrogen receptor-positive and estrogen receptor-negative mammary tumorigenesis without hypercalcemic toxicity.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:6

    Topics: Animals; Calcitriol; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Female; Humans; Hypercalcemia; Incidence; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, SCID; Models, Biological; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Xenograft Model Antitumor Assays

2008
Primary tumor cells obtained from MNU-induced mammary carcinomas show immune heterogeneity which can be modulated by low-efficiency transfection of CD40L gene.
    Cancer biology & therapy, 2009, Volume: 8, Issue:2

    Topics: Alkylating Agents; Animals; Animals, Outbred Strains; Carcinoma; CD40 Ligand; Cell Line, Tumor; Culture Media; Ethidium; Female; Fluorescent Dyes; Green Fluorescent Proteins; Immunohistochemistry; Liposomes; Mammary Neoplasms, Experimental; Methylnitrosourea; Mucin-1; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Transfection

2009
Lack of efficacy of the statins atorvastatin and lovastatin in rodent mammary carcinogenesis.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:2

    Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Anticholesteremic Agents; Antineoplastic Agents, Hormonal; Apoptosis; Atorvastatin; Bexarotene; Cell Proliferation; Diet; Disease Models, Animal; Female; Genes, erbB-2; Heptanoic Acids; Lovastatin; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Knockout; Mice, Transgenic; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Retinoid X Receptors; Tamoxifen; Tetrahydronaphthalenes; Treatment Outcome; Tumor Suppressor Protein p53

2009
Expression order of alpha-v and beta-3 integrin subunits in the N-methyl-N-nitrosourea-induced rat mammary tumor model.
    Cancer investigation, 2009, Volume: 27, Issue:5

    Topics: Adenocarcinoma; Alkylating Agents; Animals; Carcinoma, Intraductal, Noninfiltrating; Cells, Cultured; Endothelium, Vascular; Female; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Integrin alphaVbeta3; Mammary Neoplasms, Experimental; Methylnitrosourea; Protein Subunits; Rats; Rats, Wistar; Umbilical Veins

2009
Side effects of anastrozole in the experimental pre-menopausal mammary carcinogenesis.
    Neoplasma, 2009, Volume: 56, Issue:2

    Topics: Anastrozole; Animals; Aromatase Inhibitors; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitriles; Rats; Rats, Sprague-Dawley; Triazoles; Uterus; Vagina

2009
Celecoxib and melatonin in prevention of female rat mammary carcinogenesis.
    Neoplasma, 2009, Volume: 56, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Celecoxib; Drug Therapy, Combination; Eating; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides

2009
Metformin in chemically-induced mammary carcinogenesis in rats.
    Neoplasma, 2009, Volume: 56, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Drinking; Eating; Female; Hydrocortisone; Insulin-Like Growth Factor I; Lipid Peroxidation; Mammary Neoplasms, Experimental; Metformin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Triglycerides

2009
Effects of physical activity and restricted energy intake on chemically induced mammary carcinogenesis.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:4

    Topics: Alkylating Agents; AMP-Activated Protein Kinases; Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Proliferation; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Motor Activity; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases

2009
The association between phenotype and size of breast tumors induced by 1-methyl-1-nitrosourea (MNU) injection in rats.
    Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:5

    Topics: Animals; Carcinogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenotype; Rats; Rats, Sprague-Dawley

2009
Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-gamma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-15, Volume: 15, Issue:12

    Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Dietary Supplements; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; PPAR gamma; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Tocopherols; Vitamins

2009
Histological analysis of low dose NMU effects in the rat mammary gland.
    BMC cancer, 2009, Aug-03, Volume: 9

    Topics: Animals; Body Weight; Disease Models, Animal; Female; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar; Species Specificity; Time Factors

2009
Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide.
    The Journal of toxicological sciences, 2009, Volume: 34, Issue:4

    Topics: Acrylamide; Animals; Codon; Female; Gene Frequency; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Rats; Rats, Sprague-Dawley

2009
In vitro measures used to predict anticancer activity of apple cultivars and their comparison to outcomes from a rat model of experimentally induced breast cancer.
    Nutrition and cancer, 2009, Volume: 61, Issue:4

    Topics: Adenocarcinoma; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Body Weight; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Flavonoids; Freeze Drying; Fruit; Humans; Hydroxybenzoates; Inhibitory Concentration 50; Malus; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytotherapy; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors

2009
Chemopreventive efficacy of naproxen and nitric oxide-naproxen in rodent models of colon, urinary bladder, and mammary cancers.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:11

    Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Butylhydroxybutylnitrosamine; Carcinogens; Colonic Neoplasms; Diet; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Naproxen; Nitric Oxide Donors; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Urinary Bladder Neoplasms

2009
Ezetimibe reverses the inhibitory effects of dietary cholesterol on mammary tumorigenesis in rats.
    International journal of cancer, 2010, Aug-15, Volume: 127, Issue:4

    Topics: Animals; Anticholesteremic Agents; Azetidines; Carcinogens; Cholesterol, Dietary; Ezetimibe; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2010
Intrinsic susceptibility MR imaging of chemically induced rat mammary tumors: relationship to histologic assessment of hypoxia and fibrosis.
    Radiology, 2010, Volume: 254, Issue:1

    Topics: Animals; Biomarkers, Tumor; Carbon Dioxide; Female; Fibrosis; Hypoxia; Keratin-14; Linear Models; Magnetic Resonance Imaging; Mammary Neoplasms, Experimental; Methylnitrosourea; Necrosis; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Rats; Rats, Wistar

2010
Ovarian renin--angiotensin system-regulating aminopeptidases are involved in progesterone overproduction in rats with mammary tumours induced by N-methyl nitrosourea.
    Anticancer research, 2009, Volume: 29, Issue:11

    Topics: Aminopeptidases; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovary; Progesterone; Rats; Rats, Wistar; Renin-Angiotensin System

2009
The impact of fish oil on the chemopreventive efficacy of tamoxifen against development of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:3

    Topics: Alkylating Agents; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Cell Proliferation; Fatty Acids; Female; Fish Oils; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Tamoxifen

2010
Wheel running, skeletal muscle aerobic capacity and 1-methyl-1-nitrosourea induced mammary carcinogenesis in the rat.
    Carcinogenesis, 2010, Volume: 31, Issue:7

    Topics: Aerobiosis; Animals; Citrate (si)-Synthase; Female; Logistic Models; Mammary Neoplasms, Experimental; Methylnitrosourea; Muscle, Skeletal; Oxygen Consumption; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Running; Tumor Suppressor Protein p53

2010
Superior anticarcinogenic activity of trans,trans-conjugated linoleic acid in N-methyl-N-nitrosourea-induced rat mammary tumorigenesis.
    Journal of agricultural and food chemistry, 2010, May-12, Volume: 58, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Female; Linoleic Acids, Conjugated; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2010
Potential role of melatonin in DNA damage caused by nitrosourea-induced mammary carcinogenesis.
    Acta histochemica, 2011, Volume: 113, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Comet Assay; DNA Damage; Female; Leukocytes; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2011
Mammary renin-angiotensin system-regulating aminopeptidase activities are modified in rats with breast cancer.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2010, Volume: 31, Issue:6

    Topics: Aminopeptidases; Angiotensin III; Animals; CD13 Antigens; Disease Models, Animal; Female; Glutamyl Aminopeptidase; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar; Renin-Angiotensin System

2010
Long-term hormonal promotion overcomes genetic resistance to mammary cancer.
    Steroids, 2011, Volume: 76, Issue:1-2

    Topics: Animals; Estradiol; Female; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Progesterone; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Time Factors

2011
Hypothalamic cocaine- and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary carcinogenesis.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 97, Issue:2

    Topics: Animals; Anorexia; Antibody Specificity; Blood Glucose; Blood Proteins; Body Weight; Cachexia; Carcinogens; Cholesterol; Eating; Feeding Behavior; Female; Hypothalamus; Immunohistochemistry; Infusions, Intraventricular; Mammary Neoplasms, Experimental; Methylnitrosourea; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Triglycerides

2010
Wheel running-induced changes in plasma biomarkers and carcinogenic response in the 1-methyl-1-nitrosourea-induced rat model for breast cancer.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:11

    Topics: Animals; Biomarkers, Tumor; Carcinogens; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Motor Activity; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley

2010
Immune compartmentalization of T cell subsets in chemically-induced breast cancer.
    Scandinavian journal of immunology, 2010, Volume: 72, Issue:4

    Topics: Animals; CD3 Complex; Female; Flow Cytometry; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Interleukin-10; Lymph Nodes; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Natural Killer T-Cells; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocyte Subsets; T-Lymphocytes; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Transforming Growth Factor beta

2010
Breast tumors induced by N-methyl-N-nitrosourea are damaging to bone strength, structure, and mineralization in the absence of metastasis in rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011, Volume: 26, Issue:4

    Topics: Adenocarcinoma; Animals; Body Weight; Bone and Bones; Bone Density; Bone Diseases; Calcification, Physiologic; Diaphyses; Epiphyses; Female; Femur; Mammary Neoplasms, Experimental; Mechanical Phenomena; Methylnitrosourea; Neoplasm Metastasis; Rats; Rats, Sprague-Dawley

2011
Molecular histopathology by spectrally reconstructed nonlinear interferometric vibrational imaging.
    Cancer research, 2010, Dec-01, Volume: 70, Issue:23

    Topics: Animals; Breast Neoplasms; Diagnostic Imaging; Female; Humans; Interferometry; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred WF; Reproducibility of Results; Sensitivity and Specificity; Spectrum Analysis, Raman; Vibration

2010
Pre- and postpubertal irradiation induces mammary cancers with distinct expression of hormone receptors, ErbB ligands, and developmental genes in rats.
    Molecular carcinogenesis, 2011, Volume: 50, Issue:7

    Topics: Animals; Base Sequence; Carcinogens; DNA Primers; Female; Genes, ras; Immunohistochemistry; Ligands; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Radiation-Induced; Oligonucleotide Array Sequence Analysis; Oncogene Proteins v-erbB; Rats; Rats, Sprague-Dawley; Sexual Maturation

2011
Effects of 5,6-benzoflavone, indole-3-carbinol (I3C) and diindolylmethane (DIM) on chemically-induced mammary carcinogenesis: is DIM a substitute for I3C?
    Oncology reports, 2011, Volume: 26, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Epithelial Cells; Female; Indoles; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Transcription, Genetic; Tumor Burden

2011
Determinants of DHA incorporation into tumor tissue during dietary DHA supplementation.
    Lipids, 2011, Volume: 46, Issue:11

    Topics: Animals; Carcinoma; Dietary Fats; Dietary Supplements; Docosahexaenoic Acids; Fatty Acids; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Phospholipids; Rats; Rats, Sprague-Dawley; Tissue Distribution; Triglycerides

2011
Metabolic effects of pioglitazone in chemically-induced mammary carcinogenesis in rats.
    Pathology oncology research : POR, 2011, Volume: 17, Issue:4

    Topics: Animals; Corticosterone; Female; Glycogen; Heart; Hyperglycemia; Hyperinsulinism; Lipid Peroxidation; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Muscles; Myocardium; Pioglitazone; Rats; Rats, Sprague-Dawley; Thiazolidinediones; Triglycerides

2011
Mammary gland density predicts the cancer inhibitory activity of the N-3 to N-6 ratio of dietary fat.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:10

    Topics: Adipose Tissue; Alkylating Agents; Animals; Antineoplastic Agents, Hormonal; Cytokines; Diet; Enzyme-Linked Immunosorbent Assay; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Insulin-Like Growth Factor I; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen

2011
Anti-tumor effects of a novel retinoic acid metabolism blocking agent VN/14-1 in the N-methyl-N-nitrosourea-induced rat mammary carcinoma model and its effects on the uterus.
    Breast cancer research and treatment, 2012, Volume: 133, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Density; Carcinoma; Cell Size; Drug Screening Assays, Antitumor; Estradiol; Female; Imidazoles; Lipid Metabolism; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Tretinoin; Tumor Burden; Uterus

2012
MNU-induced mammary gland carcinogenesis: chemopreventive and therapeutic effects of vitamin D and Seocalcitol on selected regulatory vitamin D receptor pathways.
    Toxicology letters, 2011, Nov-10, Volume: 207, Issue:1

    Topics: Animals; Calcitriol; Cell Transformation, Neoplastic; Cholecalciferol; Female; Histocytochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Mixed Function Oxygenases; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Receptors, Calcitriol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2011
The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions.
    Breast cancer research : BCR, 2011, Aug-16, Volume: 13, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Breast Neoplasms; CD4-Positive T-Lymphocytes; CD8 Antigens; Cytokines; Epithelial Cells; Female; Genetic Loci; Genetic Predisposition to Disease; Homeostasis; L-Selectin; Mammary Neoplasms, Experimental; Methylnitrosourea; NK Cell Lectin-Like Receptor Subfamily B; Rats; Rats, Inbred WKY; Receptors, Antigen, T-Cell; T-Lymphocytes; Th1 Cells; Th2 Cells

2011
Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis.
    International journal of oncology, 2011, Volume: 39, Issue:5

    Topics: Animals; Biomarkers; Caspase 3; Cell Transformation, Neoplastic; Diet; Enzyme Activation; Fatty Acids; Female; Fish Oils; Glutathione; Glutathione Peroxidase; Ki-67 Antigen; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Oxidative Stress; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Tamoxifen; Time Factors

2011
Establishment of a mammary carcinoma cell line from Syrian hamsters treated with N-methyl-N-nitrosourea.
    Cancer letters, 2011, Dec-15, Volume: 312, Issue:1

    Topics: Adenocarcinoma; Animals; Carcinogens; Cell Line, Tumor; Cricetinae; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Mesocricetus; Methylnitrosourea

2011
Effects of short-term estrogen treatment on the progression of N-methyl-N-nitrosourea-induced premalignant mammary lesions in female Lewis rats.
    Medical molecular morphology, 2011, Volume: 44, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Cyclin D1; Estrogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred Lew

2011
Quantification of epithelial cell differentiation in mammary glands and carcinomas from DMBA- and MNU-exposed rats.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Biomarkers; Carcinoma; Cell Differentiation; Cell Division; Cell Membrane; Cell Proliferation; Epithelial Cells; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Biological; Rats; Up-Regulation

2011
A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2012, Volume: 21, Issue:2

    Topics: Algorithms; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Carcinoma; Chemoprevention; Drug Evaluation, Preclinical; Estrogen Receptor alpha; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A

2012
Effects of energy restriction and wheel running on mammary carcinogenesis and host systemic factors in a rat model.
    Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:3

    Topics: Alkylating Agents; Animals; Biomarkers, Tumor; C-Reactive Protein; Caloric Restriction; Cell Transformation, Neoplastic; Female; Insulin-Like Growth Factor I; Interleukin-6; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Running; Signal Transduction; Tumor Necrosis Factor-alpha

2012
Morphology of 1-methyl-1-nitrosourea induced rat mammary tumours after treatment with precursor of phytanic acid or its combination with vitamin D analogue.
    Endocrine regulations, 2012, Volume: 46, Issue:1

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Disease Progression; Drug Evaluation, Preclinical; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytanic Acid; Rats; Rats, Sprague-Dawley; Tumor Burden; Vitamin D

2012
Mammary cancer promotion by ovarian hormones involves IGFR/AKT/mTOR signaling.
    Steroids, 2012, Volume: 77, Issue:7

    Topics: Animals; Base Sequence; Carcinogens; DNA Primers; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovary; Progesterone; Proto-Oncogene Proteins c-akt; Rats; Real-Time Polymerase Chain Reaction; Receptors, Somatomedin; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases

2012
Melatonin enhanced bexarotene efficacy in experimental mammary carcinogenesis.
    Neoplasma, 2012, Volume: 59, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Bexarotene; Carcinogens; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Treatment Outcome

2012
Tumor and non-tumor tissues differential oxidative stress response to supplemental DHA and chemotherapy in rats.
    Cancer chemotherapy and pharmacology, 2012, Volume: 70, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Dietary Supplements; Docosahexaenoic Acids; Drug Synergism; Epirubicin; Female; Glutathione Peroxidase; Injections, Intravenous; Intestinal Mucosa; Intestines; Lipid Peroxides; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2012
Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids.
    Cancer research, 2012, Aug-01, Volume: 72, Issue:15

    Topics: Animals; Carcinogens; Carcinoma; Cell Proliferation; Cluster Analysis; Dietary Fats; Down-Regulation; Drug Evaluation, Preclinical; Fatty Acids, Omega-3; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Methylnitrosourea; Microarray Analysis; Models, Biological; Rats; Validation Studies as Topic

2012
Erufosine suppresses breast cancer in vitro and in vivo for its activity on PI3K, c-Raf and Akt proteins.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:11

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Class Ia Phosphatidylinositol 3-Kinase; Dose-Response Relationship, Drug; Female; Humans; Immunoblotting; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Mitogen-Activated Protein Kinases; Molecular Structure; Organophosphates; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; Quaternary Ammonium Compounds; ras Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Burden; Weight Loss

2012
Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations
    Carcinogenesis, 2012, Volume: 33, Issue:11

    Topics: Animals; Antineoplastic Agents; Biological Availability; Chemistry, Pharmaceutical; Curcumin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunoenzyme Techniques; Incidence; Mammary Neoplasms, Experimental; Methylnitrosourea; Nanoparticles; Polymers; Rats; Rats, Sprague-Dawley; Survival Rate; Tissue Distribution

2012
Effects of astaxanthin supplementation on chemically induced tumorigenesis in Wistar rats.
    Acta veterinaria Scandinavica, 2012, Aug-30, Volume: 54

    Topics: Animals; Antioxidants; Dietary Supplements; Female; Glutathione Peroxidase; Hematologic Tests; Lipid Peroxidation; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; Xanthophylls

2012
Individual differences in pre-carcinogen cytokine and corticosterone concentrations and depressive-like behavior predict tumor onset in rats exposed to a carcinogen.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:6

    Topics: Animals; Biomarkers; Corticosterone; Cytokines; Depression; Disease Susceptibility; Female; Individuality; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats

2013
Fish oil alters tamoxifen-modulated expression of mRNAs that encode genes related to differentiation, proliferation, metastasis, and immune response in rat mammary tumors.
    Nutrition and cancer, 2012, Volume: 64, Issue:7

    Topics: Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Corn Oil; Dietary Fats; Female; Fish Oils; Gene Expression Regulation, Neoplastic; Immunity; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymerase Chain Reaction; Rats; Reproducibility of Results; RNA, Messenger; Tamoxifen; Transcriptome

2012
[Neoplastic effect of indomethacin in N-methyl-N-nitrosourea induced mammary carcinogenesis in female rats].
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2012, Volume: 25, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Female; Indomethacin; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2012
Effects of limiting energy availability via diet and physical activity on mammalian target of rapamycin-related signaling in rat mammary carcinomas.
    Carcinogenesis, 2013, Volume: 34, Issue:2

    Topics: Adenosine Triphosphate; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Apoptosis; Blood Proteins; Blotting, Western; Caloric Restriction; Cell Cycle; Cell Proliferation; Diet; Enzyme-Linked Immunosorbent Assay; Female; Immunoenzyme Techniques; Lipids; Mammary Neoplasms, Experimental; Methylnitrosourea; NAD; NADP; Physical Conditioning, Animal; Principal Component Analysis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases

2013
Role of melatonin and luzindole in rat mammary cancer.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2012, Volume: 25, Issue:6

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Disease Models, Animal; DNA Fragmentation; Estradiol; Female; Heme Oxygenase-1; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Oxidative Stress; Progesterone; Prolactin; Rats; Rats, Sprague-Dawley; Tryptamines

2012
Body zinc distribution profile during N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats at various levels of dietary zinc intake.
    Biological trace element research, 2002,Summer, Volume: 87, Issue:1-3

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tissue Distribution; Zinc

2002
Inhibitory effects of 17beta-estradiol and 4-n-octylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats.
    Carcinogenesis, 2002, Volume: 23, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Estradiol; Female; Gene Transfer Techniques; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenols; Proto-Oncogene Mas; Rats; Tumor Cells, Cultured

2002
Preparation and biological evaluation of the new chlorin photosensitizer T3,4BCPC for detection and treatment of tumors.
    Journal of photochemistry and photobiology. B, Biology, 2002, Volume: 68, Issue:1

    Topics: Animals; Anthracenes; Female; Glioma; Isotope Labeling; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms; Photosensitizing Agents; Porphyrins; Radiopharmaceuticals; Rats; Rats, Wistar; Technetium; Time Factors; Tissue Distribution

2002
An experimental paradigm for studying the cellular and molecular mechanisms of cancer inhibition by energy restriction.
    Molecular carcinogenesis, 2002, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Animals; Caloric Restriction; Corticosterone; Diet; Energy Metabolism; Female; Insulin-Like Growth Factor I; Leptin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Estrogen

2002
Prevention and treatment of experimental breast cancer with the combination of a new selective estrogen receptor modulator, arzoxifene, and a new rexinoid, LG 100268.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Cells, Cultured; Drug Synergism; Drug Therapy, Combination; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Invasiveness; Nicotinic Acids; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Piperidines; Rats; Selective Estrogen Receptor Modulators; Stromal Cells; Tetrahydronaphthalenes; Thiophenes; Transforming Growth Factor beta

2002
Conjugated linoleic acid isomers and mammary cancer prevention.
    Nutrition and cancer, 2002, Volume: 43, Issue:1

    Topics: Animals; Carcinoma, Intraductal, Noninfiltrating; Fatty Acids, Unsaturated; Female; Linoleic Acids; Linoleic Acids, Conjugated; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors

2002
Effects of body weight gain reduction resulting from chemopreventive agent treatment on mammary gland morphology.
    Nutrition and cancer, 2002, Volume: 43, Issue:1

    Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Northern; Body Weight; Diet, Reducing; Disease Models, Animal; Estradiol; Female; Fenretinide; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley

2002
Lack of chemoprevention of indole-3-carbinol in N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats.
    IARC scientific publications, 2002, Volume: 156

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Eating; Female; Incidence; Indoles; Mammary Neoplasms, Experimental; Methylnitrosourea; Random Allocation; Rats; Time Factors

2002
Spontaneous mammary tumors in aging Noble rats.
    International journal of oncology, 2003, Volume: 22, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Age of Onset; Animals; Carcinoma; Diethylstilbestrol; Drug Implants; Estradiol; Female; Fibroadenoma; Genetic Predisposition to Disease; Incidence; Male; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Neoplasm Transplantation; Ovariectomy; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Rodent Diseases; Species Specificity; Testosterone

2003
Suppression of mammary gland tumorigenesis in diabetic rats.
    Cancer detection and prevention, 2003, Volume: 27, Issue:1

    Topics: Alkylating Agents; Animals; Diabetes Mellitus, Experimental; Female; Genes, fos; Immunohistochemistry; Insulin; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Pancreas; Proliferating Cell Nuclear Antigen; Rats; Time Factors

2003
Cell proliferation, apoptosis, and expression of cyclin D1 and cyclin E as potential biomarkers in tamoxifen-treated mammary tumors.
    Breast cancer research and treatment, 2003, Volume: 77, Issue:3

    Topics: Animals; Biomarkers, Tumor; Blotting, Western; Cell Division; Cyclin D1; Cyclin E; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Estrogen Receptor Modulators; Tamoxifen; Tumor Cells, Cultured

2003
Effect of energy restriction on cell cycle machinery in 1-methyl-1-nitrosourea-induced mammary carcinomas in rats.
    Cancer research, 2003, Mar-15, Volume: 63, Issue:6

    Topics: Adenocarcinoma; Animals; Caloric Restriction; Carcinogens; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptors, Estrogen; Retinoblastoma Protein; Transcription Factors

2003
An expression study of hormone receptors in spontaneously developed, carcinogen-induced and hormone-induced mammary tumors in female Noble rats.
    International journal of oncology, 2003, Volume: 22, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; DNA Primers; Female; Hormones; Immunohistochemistry; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymerase Chain Reaction; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin

2003
Dietary folate deficiency suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats.
    Carcinogenesis, 2003, Volume: 24, Issue:5

    Topics: Adenocarcinoma; Adenoma; Alkylating Agents; Animals; Body Weight; Diet; DNA Methylation; DNA, Neoplasm; Female; Folic Acid; Folic Acid Deficiency; Incidence; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2003
Zinc accumulation in N-methyl-N-nitrosourea-induced rat mammary tumors is accompanied by an altered expression of ZnT-1 and metallothionein.
    Experimental biology and medicine (Maywood, N.J.), 2003, Volume: 228, Issue:6

    Topics: Animals; Carrier Proteins; Cation Transport Proteins; DNA Primers; Female; Iron-Binding Proteins; Mammary Neoplasms, Experimental; Membrane Proteins; Membrane Transport Proteins; Metallothionein; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution; Zinc

2003
Mechanisms by which energy restriction inhibits rat mammary carcinogenesis: in vivo effects of corticosterone on cell cycle machinery in mammary carcinomas.
    Carcinogenesis, 2003, Volume: 24, Issue:7

    Topics: Adenocarcinoma; Animals; Blotting, Western; Body Weight; Caloric Restriction; Cell Cycle; Cell Cycle Proteins; Corticosterone; Diet; Female; Glucocorticoids; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Precipitin Tests; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptors, Estrogen; Up-Regulation

2003
Analysis of altered gene expression profiles in retinoic acid or CpG-treated Sprague-Dawley rats with MNU-induced mammary adenocarcinoma by cDNA macro array.
    General physiology and biophysics, 2003, Volume: 22, Issue:1

    Topics: Adenocarcinoma; Animals; CpG Islands; DNA Mutational Analysis; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Methylnitrosourea; Oligodeoxyribonucleotides; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Spleen; Tretinoin

2003
Dietary docosahexaenoic acid suppresses N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats more effectively than eicosapentaenoic acid.
    Nutrition and cancer, 2003, Volume: 45, Issue:2

    Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Random Allocation; Rats; Rats, Sprague-Dawley

2003
VIP grafted sterically stabilized liposomes for targeted imaging of breast cancer: in vivo studies.
    Journal of controlled release : official journal of the Controlled Release Society, 2003, Aug-28, Volume: 91, Issue:1-2

    Topics: Animals; Carcinogens; Drug Carriers; Drug Compounding; Female; Image Processing, Computer-Assisted; Liposomes; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms; Particle Size; Radionuclide Imaging; Radiopharmaceuticals; Rats; Technetium Tc 99m Exametazime; Tissue Distribution; Vasoactive Intestinal Peptide

2003
Radiosensitivity of rat mammary tumors correlates with early vessel changes assessed by power Doppler sonography.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2003, Volume: 22, Issue:9

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Animal; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Sodium Chloride; Statistics, Nonparametric; Ultrasonography, Doppler

2003
Chemomodulatory influence of Ferula asafoetida on mammary epithelial differentiation, hepatic drug metabolizing enzymes, antioxidant profiles and N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats.
    Breast cancer research and treatment, 2003, Volume: 81, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Differentiation; Cytochrome P-450 Enzyme System; Enzyme Induction; Epithelial Cells; Female; Ferula; Lipid Peroxidation; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Plant Preparations; Rats; Rats, Sprague-Dawley; Xenobiotics

2003
Changes in tumor vascularization after irradiation, anthracyclin, or antiangiogenic treatment in nitrosomethyl ureas-induced rat mammary tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Oct-01, Volume: 9, Issue:12

    Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Cyclohexanes; Epirubicin; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Animal; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Radiotherapy Dosage; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Ultrasonography, Doppler

2003
Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats.
    Carcinogenesis, 2004, Volume: 25, Issue:2

    Topics: Adenocarcinoma; Alkylating Agents; Animal Feed; Animals; Anticarcinogenic Agents; Cell Division; Diet; Drug Synergism; Estrogens; Female; Genistein; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Uterus

2004
9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers.
    Cancer letters, 2003, Nov-10, Volume: 201, Issue:1

    Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Chromatography, High Pressure Liquid; Diet; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Naphthalenes; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Tamoxifen; Transcription Factors

2003
Treatment of 1-methyl-1-nitrosourea-induced mammary tumours with immunostimulatory CpG motifs and 13-cis retinoic acid in female rats: histopathological study.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2003, Volume: 55, Issue:2-3

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; CpG Islands; Disease Models, Animal; Drug Therapy, Combination; Female; Isotretinoin; Mammary Neoplasms, Experimental; Methylnitrosourea; Oligodeoxyribonucleotides; Rats; Treatment Outcome

2003
Effect of PSC 833, an inhibitor of P-glycoprotein on N-methyl-N-nitrosourea induced mammary carcinogenesis in rats.
    Carcinogenesis, 2004, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinogens; Cyclosporins; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats

2004
Prepubertal resveratrol exposure accelerates N-methyl-N-nitrosourea-induced mammary carcinoma in female Sprague-Dawley rats.
    Cancer letters, 2003, Dec-30, Volume: 202, Issue:2

    Topics: Age Factors; Alkylating Agents; Animals; Body Weight; Dose-Response Relationship, Drug; Estrous Cycle; Female; Isoflavones; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes

2003
Chemoprevention of mammary carcinogenesis in female rats by rofecoxib.
    Cancer letters, 2003, Dec-30, Volume: 202, Issue:2

    Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diet; Dose-Response Relationship, Drug; Female; Lactones; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Sulfones

2003
NMU-induced mammary carcinogenesis in female rats is influenced by repeated psychoemotional stress.
    Neoplasma, 2003, Volume: 50, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Time Factors

2003
Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma.
    Cancer research, 2004, Feb-01, Volume: 64, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Carcinogens; Celecoxib; Cell Cycle; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Synergism; Female; Fluorenes; Isoenzymes; Leucine; Mammary Neoplasms, Experimental; Methylnitrosourea; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Transcription Factors

2004
Enhanced radiosensitivity of rat autochthonous mammary tumors by dietary docosahexaenoic acid.
    International journal of cancer, 2004, Apr-10, Volume: 109, Issue:3

    Topics: Alkylating Agents; Animals; Antioxidants; Dietary Fats, Unsaturated; Dietary Supplements; Docosahexaenoic Acids; Female; Lipids; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Vitamin E

2004
The stroma as a crucial target in rat mammary gland carcinogenesis.
    Journal of cell science, 2004, Mar-15, Volume: 117, Issue:Pt 8

    Topics: Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Extracellular Matrix; Female; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Neoplasm Transplantation; Rats; Rats, Inbred WF; Stromal Cells

2004
Immunobiological characterization of N -nitrosomethylurea-induced rat breast carcinomas: tumoral IL-10 expression as a possible immune escape mechanism.
    Breast cancer research and treatment, 2004, Volume: 84, Issue:2

    Topics: Animals; Cytokines; Disease Models, Animal; Female; Immunohistochemistry; Interleukin-10; Leukocytes; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar

2004
Watch thy neighbor: cancer is a communal affair.
    Journal of cell science, 2004, Mar-15, Volume: 117, Issue:Pt 8

    Topics: Alkylating Agents; Animals; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Extracellular Matrix; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Neoplasm Transplantation; Rats; Rats, Inbred WF; Stromal Cells

2004
Prepubertal zearalenone exposure suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis but causes severe endocrine disruption in female Sprague-Dawley rats.
    Nutrition and cancer, 2003, Volume: 47, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovulation; Random Allocation; Rats; Rats, Sprague-Dawley; Sexual Maturation; Time Factors; Zearalenone

2003
Downregulation of estrogen receptor alpha and beta expression in carcinogen-induced mammary gland tumors of rats.
    Eksperimental'naia onkologiia, 2004, Volume: 26, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Down-Regulation; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley

2004
Adrenalectomy does not block the inhibition of mammary carcinogenesis by dietary energy restriction in rats.
    The Journal of nutrition, 2004, Volume: 134, Issue:5

    Topics: Adrenalectomy; Animals; Blood Glucose; Body Weight; Caloric Restriction; Female; Hormones; Incidence; Insulin-Like Growth Factor Binding Proteins; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Second Primary; Rats; Rats, Sprague-Dawley; Time Factors

2004
Low zinc intake suppressed N-methyl-N-nitrosourea-induced mammary tumorigenesis in Sprague-Dawley rats.
    Carcinogenesis, 2004, Volume: 25, Issue:10

    Topics: Animals; Body Weight; Carcinogens; Diet; Eating; Female; Incidence; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Weight Gain; Zinc

2004
Insulin-like growth factor (IGF)-I obliterates the pregnancy-associated protection against mammary carcinogenesis in rats: evidence that IGF-I enhances cancer progression through estrogen receptor-alpha activation via the mitogen-activated protein kinase
    Breast cancer research : BCR, 2004, Volume: 6, Issue:4

    Topics: Adenocarcinoma; Animals; Carcinoma, Ductal; Carcinoma, Papillary; Estrogen Receptor alpha; Female; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitogen-Activated Protein Kinases; Parity; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Receptors, Estrogen

2004
Serum oxytocinase activity is related to tumor growth parameters in N-methyl nitrosourea induced rat breast cancer.
    Life sciences, 2004, Jul-30, Volume: 75, Issue:11

    Topics: Animals; Body Weight; Carcinogens; Cystinyl Aminopeptidase; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar

2004
Targeting angiogenesis for mammary cancer prevention: factors to consider in experimental design and analysis.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:7

    Topics: Angiogenesis Inducing Agents; Animals; Carcinogens; Carcinoma in Situ; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Research Design

2004
Immuno-neutralization of circulating relaxin does not alter the breast cancer-protective action of parity in MNU-treated rats.
    Journal of experimental therapeutics & oncology, 2004, Volume: 4, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Birth Rate; Carcinogens; Cervix Uteri; Female; Immunization, Passive; Mammary Neoplasms, Experimental; Methylnitrosourea; Parity; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Relaxin

2004
Effect of dietary energy restriction on vascular density during mammary carcinogenesis.
    Cancer research, 2004, Aug-15, Volume: 64, Issue:16

    Topics: Animals; Blotting, Western; Caloric Restriction; Carcinogens; Cell Division; Endothelium, Vascular; Female; Gene Expression Regulation, Neoplastic; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Weight Loss

2004
Lack of effects of postnatal exposure to a mixture of aryl hydrocarbon-receptor agonists on the development of methylnitrosourea-induced mammary tumors in sprague-dawley rats.
    Journal of toxicology and environmental health. Part A, 2004, Sep-24, Volume: 67, Issue:18

    Topics: Age Factors; Alkylating Agents; Animals; Animals, Newborn; Benzofurans; Body Weight; Dibenzofurans, Polychlorinated; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Environmental Exposure; Environmental Pollutants; Estrous Cycle; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Milk; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Risk Factors

2004
Inhibition of mammary gland tumors by short-term treatment of estradiol-3-benzoate associated with down-regulation of estrogen receptor ERalpha and ERbeta.
    Oncology reports, 2004, Volume: 12, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Carcinogens; Cell Differentiation; Down-Regulation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2004
Dietary effects of conjugated docosahexaenoic acid on N-methyl-N-nitrosourea-induced mammary carcinogenesis in female Sprague-Dawley rats.
    Oncology reports, 2004, Volume: 12, Issue:5

    Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Diet; Docosahexaenoic Acids; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2004
Mammary tumorigenesis in growth hormone deficient spontaneous dwarf rats; effects of hormonal treatments.
    Breast cancer research and treatment, 2004, Volume: 87, Issue:3

    Topics: Administration, Oral; Animals; Blotting, Western; Estradiol; Female; Growth Hormone; Injections, Subcutaneous; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley

2004
Chemoprevention by grape seed extract and genistein in carcinogen-induced mammary cancer in rats is diet dependent.
    The Journal of nutrition, 2004, Volume: 134, Issue:12 Suppl

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chemoprevention; Diet; Dietary Supplements; Female; Genistein; Isoflavones; Mammary Neoplasms, Experimental; Methylnitrosourea; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds; Vitis

2004
Efficacy of Targretin on methylnitrosourea-induced mammary cancers: prevention and therapy dose-response curves and effects on proliferation and apoptosis.
    Carcinogenesis, 2005, Volume: 26, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Cell Division; Diet; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Retinoid X Receptors; Tamoxifen

2005
Cooperative induction of rat mammary cancer by radiation and 1-methyl-1-nitrosourea via the oncogenic pathways involving c-Myc activation and H-ras mutation.
    International journal of cancer, 2005, Jun-10, Volume: 115, Issue:2

    Topics: Adenocarcinoma; Alkylating Agents; Animals; Cocarcinogenesis; Female; Fibroadenoma; Gamma Rays; Genes, ras; Humans; Incidence; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Survival Rate

2005
Endothelin-1-induced vasodilatation in rat breast tumor is mediated through endothelin-B receptors.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Animals; Blood Flow Velocity; Endothelin B Receptor Antagonists; Endothelin-1; Female; Infusions, Intralesional; Laser-Doppler Flowmetry; Mammary Neoplasms, Experimental; Methylnitrosourea; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Regional Blood Flow; Time Factors; Vascular Resistance; Vasodilation

2004
Alpha-tocopherol suppresses mammary tumor sensitivity to anthracyclines in fish oil-fed rats.
    Nutrition and cancer, 2005, Volume: 51, Issue:2

    Topics: Adipose Tissue; alpha-Tocopherol; Animals; Anthracyclines; Antibiotics, Antineoplastic; Antioxidants; Carcinogens; Diet; Disease Models, Animal; Drug Antagonism; Drug Resistance, Neoplasm; Epirubicin; Fatty Acids, Unsaturated; Female; Fish Oils; Malondialdehyde; Mammary Neoplasms, Experimental; Methylnitrosourea; Oxidants; Rats; Rats, Sprague-Dawley; Time Factors

2005
Effect of perductal paclitaxel exposure on the development of MNU-induced mammary carcinoma in female S-D rats.
    Breast cancer research and treatment, 2005, Volume: 91, Issue:1

    Topics: Alkylating Agents; Animals; Antineoplastic Agents, Phytogenic; Female; Infusions, Parenteral; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Paclitaxel; Rats; Rats, Sprague-Dawley

2005
Effects of dietary folate on the development and progression of mammary tumors in rats.
    Carcinogenesis, 2005, Volume: 26, Issue:9

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Diet; Female; Folic Acid; Folic Acid Deficiency; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2005
Inhibition of NMU-induced mammary tumorigenesis by dietary soy.
    Cancer letters, 2005, Jun-16, Volume: 224, Issue:1

    Topics: Alkylating Agents; Animals; Apoptosis; Breast Neoplasms; Cell Proliferation; Chemoprevention; Diet; Disease Models, Animal; Female; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Receptor, ErbB-2; Receptors, Progesterone; Soybean Proteins

2005
Inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis by molecular iodine (I2) but not by iodide (I-) treatment Evidence that I2 prevents cancer promotion.
    Molecular and cellular endocrinology, 2005, May-31, Volume: 236, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Chloride-Bicarbonate Antiporters; Female; Incidence; Iodides; Iodine; Lipid Peroxidation; Mammary Neoplasms, Experimental; Methylnitrosourea; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sulfate Transporters; Thyroxine; Up-Regulation

2005
Hypermethylation patterns in the Fhit regulatory region are tissue specific.
    Molecular carcinogenesis, 2005, Volume: 43, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acid Anhydride Hydrolases; Animals; Base Sequence; Carcinogens; DNA Methylation; DNA Primers; Female; Gene Expression Regulation; Genes, Regulator; Genes, Tumor Suppressor; Introns; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Proteins; Organ Specificity; Polymerase Chain Reaction; Rats

2005
Regression of NMU-induced mammary tumors with the combination of melatonin and 9-cis-retinoic acid.
    Cancer letters, 2005, Sep-08, Volume: 227, Issue:1

    Topics: Alitretinoin; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Estrogen Receptor alpha; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tretinoin

2005
Chemoprevention of chemically-induced mammary and colon carcinogenesis by 1alpha-hydroxyvitamin D5.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 97, Issue:1-2

    Topics: Animals; beta Catenin; Chemoprevention; Colonic Neoplasms; Diet; Female; Hydroxycholecalciferols; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Conformation; Organ Specificity; Rats; Rats, Sprague-Dawley; Wnt1 Protein

2005
Optical biopsy of lymph node morphology using optical coherence tomography.
    Technology in cancer research & treatment, 2005, Volume: 4, Issue:5

    Topics: Animals; Biopsy; Female; Humans; Image Processing, Computer-Assisted; Lymph Nodes; Mammary Neoplasms, Experimental; Mammography; Methylnitrosourea; Rats; Tomography, Optical

2005
MNU-induced carcinogenesis of rat mammary gland: effect of thyroid hormone on expression of retinoic acid receptors in tumours of mammary gland.
    Molecular and cellular endocrinology, 2005, Dec-01, Volume: 244, Issue:1-2

    Topics: Animals; Carcinogens; Female; Gene Expression; Hyperthyroidism; Hypothyroidism; Mammary Neoplasms, Experimental; Methylnitrosourea; Propylthiouracil; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; RNA, Messenger; Thyroid Hormones; Thyroidectomy

2005
AT1 receptor and ACE mRNA are increased in chemically induced carcinoma of rat mammary gland.
    Molecular and cellular endocrinology, 2005, Dec-01, Volume: 244, Issue:1-2

    Topics: Angiotensinogen; Animals; Female; Gene Expression; Isotretinoin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2005
Prevention of N-methyl-N-nitrosourea-induced breast cancer by alpha-fetoprotein (AFP)-derived peptide, a peptide derived from the active site of AFP.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Dec-01, Volume: 11, Issue:23

    Topics: Alkylating Agents; alpha-Fetoproteins; Animals; Binding Sites; Female; Humans; Incidence; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, SCID; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Tissue Distribution; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2005
Efficacy of the farnesyltransferase inhibitor R115777 in a rat mammary tumor model: role of Ha-ras mutations and use of microarray analysis in identifying potential targets.
    Carcinogenesis, 2006, Volume: 27, Issue:7

    Topics: Alkylating Agents; Animals; Farnesyltranstransferase; Female; Gene Expression; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Oligonucleotide Array Sequence Analysis; Quinolones; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction

2006
Effect of glibenclamide on N-nitroso-N-methylurea-induced mammary tumors in diabetic and nondiabetic rats.
    Oncology research, 2005, Volume: 15, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blood Glucose; Diabetes Mellitus, Experimental; Drug Interactions; Female; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen

2005
Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism.
    Breast cancer research : BCR, 2005, Volume: 7, Issue:6

    Topics: Adjuvants, Immunologic; Alkylating Agents; Animals; Breast Neoplasms; Carcinoma in Situ; Cell Transformation, Neoplastic; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Dehydroepiandrosterone; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53

2005
Renin-angiotensin system-regulating aminopeptidase activities are modified in the pineal gland of rats with breast cancer induced by N-methyl-nitrosourea.
    Cancer investigation, 2006, Volume: 24, Issue:2

    Topics: Alkylating Agents; Aminopeptidases; Angiotensin II; Animals; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Pineal Gland; Rats; Renin-Angiotensin System

2006
Refractive index of carcinogen-induced rat mammary tumours.
    Physics in medicine and biology, 2006, May-07, Volume: 51, Issue:9

    Topics: Animals; Carcinogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Refractometry; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Infrared

2006
Effects of the farnesyl transferase inhibitor R115777 (Zarnestra) on mammary carcinogenesis: prevention, therapy, and role of HaRas mutations.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Apoptosis; Carcinogens; Cell Division; Enzyme Inhibitors; Farnesyltranstransferase; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Quinolones; Rats; Rats, Sprague-Dawley

2006
[Mast cells of the mammary gland and of the regional lymph node in rats with breast cancer induced by N-methyl-N-nitrosourea].
    Morfologiia (Saint Petersburg, Russia), 2005, Volume: 128, Issue:5

    Topics: Animals; Carcinogens; Cell Degranulation; Female; Lymph Nodes; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mast Cells; Methylnitrosourea; Microscopy, Electron, Transmission; Rats

2005
A comparative study on the protective effects of 17beta-estradiol, biochanin A and bisphenol A on mammary gland differentiation and tumorigenesis in rats.
    Indian journal of experimental biology, 2006, Volume: 44, Issue:7

    Topics: Animals; Animals, Newborn; Anticarcinogenic Agents; Benzhydryl Compounds; Body Weight; Cell Differentiation; Dose-Response Relationship, Drug; Estradiol; Female; Genistein; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Phenols; Rats; Rats, Sprague-Dawley

2006
Letter to the editor.
    Molecular and cellular endocrinology, 2006, Sep-26, Volume: 257-258

    Topics: Animals; Data Interpretation, Statistical; Female; Iodine; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Treatment Outcome

2006
Characterization of a preclinical model of simultaneous breast and ovarian cancer progression.
    Carcinogenesis, 2007, Volume: 28, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Alkylating Agents; Animals; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Cell Proliferation; Cells, Cultured; Cocarcinogenesis; Cyclooxygenase 2; Disease Models, Animal; Disease Progression; Epithelium; Estrogen Receptor alpha; Estrogens; Female; Hyperplasia; Immunoenzyme Techniques; Ki-67 Antigen; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovarian Neoplasms; Precancerous Conditions; Rats; Rats, Inbred F344

2007
Antitumour action of 5,6-dimethylxanthenone-4-acetic acid in rats bearing chemically induced primary mammary tumours.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Cytokines; Female; Immunoassay; In Situ Nick-End Labeling; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Xanthones

2007
Sensitization by dietary docosahexaenoic acid of rat mammary carcinoma to anthracycline: a role for tumor vascularization.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Oct-01, Volume: 12, Issue:19

    Topics: Alkylating Agents; alpha-Tocopherol; Animals; Antibiotics, Antineoplastic; Antioxidants; Dietary Supplements; Docosahexaenoic Acids; Epirubicin; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A

2006
Urinary phytoestrogen excretion of rats bearing methylnitrosourea-induced mammary carcinoma in response to treatment with 2-methoxyestradiol.
    The Journal of steroid biochemistry and molecular biology, 2007, Volume: 103, Issue:2

    Topics: 2-Methoxyestradiol; Animals; Carcinoma; Coumestrol; Estradiol; Female; Isoflavones; Lignans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytoestrogens; Rats; Rats, Sprague-Dawley

2007
Loss of chromosomal integrity drives rat mammary tumorigenesis.
    International journal of cancer, 2007, Mar-01, Volume: 120, Issue:5

    Topics: Animals; Antigens, Neoplasm; Aurora Kinase A; Aurora Kinases; Carcinoma; Cell Transformation, Neoplastic; Centrosome; Chromosomal Instability; Female; Karyotyping; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Polyploidy; Protein Serine-Threonine Kinases; Rats; Rats, Inbred WF

2007
Mammary carcinogenesis in transgenic mice expressing a dominant-negative mutant of DNA polymerase beta in their mammary glands.
    Carcinogenesis, 2007, Volume: 28, Issue:6

    Topics: Animals; Cattle; Cell Line, Transformed; DNA Polymerase beta; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Nude; Mice, Transgenic

2007
In utero exposure to maternal diets containing soy protein isolate, but not genistein alone, protects young adult rat offspring from NMU-induced mammary tumorigenesis.
    Carcinogenesis, 2007, Volume: 28, Issue:5

    Topics: Animals; Cadherins; Diet; Female; Genistein; Mammary Neoplasms, Experimental; Methylnitrosourea; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Soybean Proteins

2007
Serial transplantation of NMU-induced rat mammary tumors: a model of human breast cancer progression.
    International journal of cancer, 2007, Aug-01, Volume: 121, Issue:3

    Topics: Animals; Disease Models, Animal; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Invasiveness; Neoplasm Transplantation; Rats; Rats, Inbred WF

2007
Effect of prolonged psychoemotional stress and melatonin on experimental mammary carcinogenesis in female rats.
    Neoplasma, 2007, Volume: 54, Issue:3

    Topics: Animals; Antioxidants; Carcinogens; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Stress, Psychological

2007
Advanced rat mammary cancers are growth hormone dependent.
    Endocrinology, 2007, Volume: 148, Issue:10

    Topics: Animals; Disease Susceptibility; Drug Administration Schedule; Dwarfism; Growth Hormone; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Remission Induction

2007
N-methyl-N-nitrosourea-induced mammary carcinogenesis is promoted by short-term treatment with estrogen and progesterone mimicking pregnancy in aged female Lewis rats.
    Oncology reports, 2007, Volume: 18, Issue:2

    Topics: Aging; Alkylating Agents; Animals; Drug Combinations; Drug Implants; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Necrosis; Pregnancy; Progesterone; Rats; Rats, Inbred Lew; Weight Gain

2007
Short-term modulation of cell proliferation and apoptosis and preventive/therapeutic efficacy of various agents in a mammary cancer model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Sep-15, Volume: 13, Issue:18 Pt 1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers; Cell Proliferation; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2007
Mixed tocopherols inhibit N-methyl-N-nitrosourea-induced mammary tumor growth in rats.
    Nutrition and cancer, 2007, Volume: 59, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Tocopherols

2007
Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens.
    Cancer research, 2007, Dec-01, Volume: 67, Issue:23

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Animals; Animals, Genetically Modified; Blotting, Western; Breast; Breast Neoplasms; Carcinogens; Cells, Cultured; Female; Gene Silencing; Genes, ras; Glutathione Peroxidase; Humans; Imidazoles; Mammary Neoplasms, Experimental; Methylnitrosourea; Middle Aged; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tumor Suppressor Protein p53

2007
Preventive effects of letrozole in the model of premenopausal mammary carcinogenesis.
    Neoplasma, 2008, Volume: 55, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Drug Screening Assays, Antitumor; Female; Letrozole; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Nitriles; Rats; Rats, Sprague-Dawley; Triazoles

2008
Induction of a novel histone deacetylase 1/c-Myc/Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis.
    Cancer science, 2008, Volume: 99, Issue:2

    Topics: Animals; Animals, Genetically Modified; Basic-Leucine Zipper Transcription Factors; Cell Differentiation; Cell Proliferation; Female; Histone Deacetylase 1; Histone Deacetylases; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Parity; Pregnancy; Proto-Oncogene Proteins c-myc; Rats; Repressor Proteins

2008
Effects of gefitinib (Iressa) on mammary cancers: preventive studies with varied dosages, combinations with vorozole or targretin, and biomarker changes.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bexarotene; Biomarkers, Tumor; Carcinogens; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Therapy, Combination; ErbB Receptors; Female; Gefitinib; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Triazoles

2008
Hormonal prevention of breast cancer: significance of promotional environment.
    Advances in experimental medicine and biology, 2008, Volume: 617

    Topics: Animals; Carcinogens; Cell Proliferation; Cyclin D; Cyclins; Estradiol; Estrogens; Female; Incidence; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Pregnancy; Rats; Rats, Inbred Lew

2008
Effect of a high dosage of ketoconazole all or not combined with ovariectomy on N-nitroso-N-methylurea-induced mammary cancer in the rat.
    Cancer letters, 1984, Volume: 24, Issue:2

    Topics: Animals; Castration; Combined Modality Therapy; Female; Ketoconazole; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors

1984
The effect of copper on the binding of prostaglandin E1 to NMU-induced rat mammary carcinoma membranes.
    Prostaglandins, leukotrienes, and medicine, 1983, Volume: 12, Issue:2

    Topics: Alprostadil; Animals; Binding, Competitive; Cell Membrane; Female; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosourea; Prostaglandins E; Rats; Rats, Inbred BUF; Receptors, Cell Surface; Receptors, Prostaglandin; Receptors, Prostaglandin E

1983
Ultrastructural study of membrane glycocalyx in primary and metastatic human and rat mammary carcinoma.
    Journal of surgical oncology, 1981, Volume: 17, Issue:4

    Topics: Animals; Breast Neoplasms; Cell Membrane; Female; Glycoproteins; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Microscopy, Electron; Neoplasm Transplantation; Polysaccharides; Rats; Ruthenium Red

1981
Effect of short-term administration of N-(4-hydroxyphenyl)-all-trans-retinamide on chemically induced mammary tumors.
    Nutrition and cancer, 1983, Volume: 4, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tretinoin

1983
Characterization of estradiol, progesterone, and prolactin receptors in nitrosomethylurea-induced mammary tumors and effect of antiestrogen treatment on the development and growth of these tumors.
    Cancer research, 1980, Volume: 40, Issue:9

    Topics: Animals; Castration; Centrifugation, Density Gradient; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Prolactin; Rats; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone

1980
Effect of ovariectomy on hormone receptors and growth of N-nitrosomethylurea-induced mammary tumors in the rat.
    Cancer research, 1980, Volume: 40, Issue:12

    Topics: Animals; Castration; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Rats; Receptors, Cell Surface; Receptors, Prolactin; Receptors, Steroid

1980
Correlation between retinoid inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis and levels of retinoic acid binding proteins.
    Carcinogenesis, 1982, Volume: 3, Issue:1

    Topics: Animals; Carrier Proteins; Cytosol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Proteins; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Receptors, Retinoic Acid; Vitamin A

1982
Effect of high-dose oestrogen administration on the growth and prolactin receptor content of N-nitrosomethylurea-induced mammary tumours in the rat.
    The Journal of endocrinology, 1982, Volume: 93, Issue:1

    Topics: Animals; Cell Division; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Perphenazine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prolactin

1982
Role of estrogen and prolactin in the growth and receptor levels of N-nitrosomethylurea-induced rat mammary tumors.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Animals; Bromocriptine; Castration; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Perphenazine; Prolactin; Rats; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Prolactin; Tamoxifen

1982
N-nitroso-N-methylurea-induced mammary tumors in the rat: role of prolactin and a prolactin-lowering drug.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:1

    Topics: Animals; Bromocriptine; Castration; Cytosol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin

1983
Nuclear interactions of retinoic acid-binding protein in chemically induced mammary adenocarcinoma.
    The Biochemical journal, 1982, Dec-15, Volume: 208, Issue:3

    Topics: Adenocarcinoma; Animals; Binding Sites; Carrier Proteins; Cell Nucleus; Centrifugation, Density Gradient; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Proteins; Rats; Rats, Inbred Strains; Receptors, Retinoic Acid; Tretinoin

1982
Nuclear thyroid hormone receptors, alpha-glycerophosphate dehydrogenases, and malic enzyme in N-nitrosomethylurea-induced rat mammary tumors.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Animals; Binding, Competitive; Cell Nucleus; Cytosol; Female; Glycerolphosphate Dehydrogenase; Liver; Malate Dehydrogenase; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitochondria; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Thyroidectomy; Triiodothyronine

1983
Prolactin-like activity of antiprolactin receptor antibodies in rat mammary tumor explants.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Animals; Antibodies; Caseins; Cross Reactions; DNA; Dose-Response Relationship, Drug; Female; Lactose Synthase; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Prolactin; Rats; Receptors, Cell Surface

1983
Prolactin receptors in explant cultures of carcinogen-induced rat mammary tumors.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chloroquine; Colchicine; Cycloheximide; Cytochalasin B; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Organoids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prolactin

1983
Effects of reserpine administration on rat mammary tumors and uterine disease induced by N-nitrosomethylurea.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin; Reserpine; Uterine Diseases; Uterus

1983
Dietary lipid effects on the growth, membrane composition, and prolactin-binding capacity of rat mammary tumors.
    Journal of the National Cancer Institute, 1984, Volume: 73, Issue:1

    Topics: Animals; Castration; Cell Division; Dietary Fats; Fatty Acids; Female; Intracellular Membranes; Mammary Neoplasms, Experimental; Membrane Lipids; Methylnitrosourea; Microsomes; Microsomes, Liver; Prolactin; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, Prolactin

1984
Retinoid feeding, hormone inhibition, and/or immune stimulation and the progression of N-methyl-N-nitrosourea-induced rat mammary carcinoma: suppression by retinoids of peptide hormone-induced tumor cell proliferation in vivo and in vitro.
    Cancer research, 1984, Volume: 44, Issue:1

    Topics: Animals; Diterpenes; DNA Replication; Female; Freund's Adjuvant; Haloperidol; Immunization; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Prolactin; Rats; Rats, Inbred Strains; Retinyl Esters; Tretinoin; Vitamin A

1984
Effect of tamoxifen and alpha-difluoromethylornithine on clones of nitrosomethylurea-induced rat mammary tumor cells grown in soft agar culture.
    Cancer research, 1983, Volume: 43, Issue:3

    Topics: Agar; Animals; Cells, Cultured; Clone Cells; Dose-Response Relationship, Drug; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Ornithine; Rats; Rats, Inbred Strains; Tamoxifen

1983
Modulation of tumor incidence and possible mechanisms of inhibition of mammary carcinogenesis by dietary antioxidants.
    Cancer research, 1983, Volume: 43, Issue:5 Suppl

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antioxidants; Body Weight; Diet; Dietary Fats; Drug Interactions; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Oxidoreductases; Rats; Rats, Inbred Strains

1983
Prostaglandin concentrations and prostaglandin synthetase activity in N-nitrosomethylurea-induced rat mammary adenocarcinoma.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Adenocarcinoma; Animals; Dinoprost; Dinoprostone; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Microsomes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Thromboxane B2

1983
Experiments on the influence of combined application of N-methylnitrosourea and 7,12-dimethylbenzanthracene in female Sprague-Dawley rats.
    Archiv fur Geschwulstforschung, 1983, Volume: 53, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Benz(a)Anthracenes; Drug Synergism; Female; Injections, Intravenous; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains

1983
Polyamines as mediators of estrogen action on the growth of experimental breast cancer in rats.
    Journal of the National Cancer Institute, 1984, Volume: 73, Issue:2

    Topics: Animals; Cell Aggregation; Eflornithine; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine

1984
Effect of arginine on the carcinogenicity of 7,12-dimethylbenz[a]-anthracene and N-methyl-N-nitrosourea.
    Carcinogenesis, 1984, Volume: 5, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arginine; Diet; DNA; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains

1984
Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)retinamide and ovariectomy.
    Cancer research, 1982, Volume: 42, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Diet; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors; Tretinoin

1982
Influence of nicotine on N-nitrosomethylurea-induced mammary tumors in rats.
    Klinische Wochenschrift, 1984, Volume: 62 Suppl 2

    Topics: Adenoma; Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nicotine; Rats; Rats, Inbred Strains

1984
Influence of dietary medium-chain triglycerides on the development of N-methylnitrosourea-induced rat mammary tumors.
    Cancer research, 1984, Volume: 44, Issue:11

    Topics: Adenocarcinoma; Adenofibroma; Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred F344; Risk; Structure-Activity Relationship; Triglycerides

1984
Effect of prospidine administered at different times of the day on the development and growth of N-nitrosomethylurea-induced mammary tumors in Wistar rats.
    Cancer letters, 1984, Volume: 24, Issue:1

    Topics: Animals; Antineoplastic Agents; Circadian Rhythm; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Piperazines; Prospidium; Rats; Rats, Inbred Strains; Time Factors

1984
Growth enhancement of N-nitrosomethylurea-induced rat mammary tumor cells in soft agar by estrogen or prolactin.
    Cancer research, 1984, Volume: 44, Issue:12 Pt 1

    Topics: Agar; Animals; Cell Division; Cells, Cultured; Culture Media; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Rats; Rats, Inbred Strains

1984
The mitochondrial genetic system as a target for chemotherapy: tetracyclines as cytostatics.
    Cancer letters, 1984, Volume: 25, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cricetinae; Doxycycline; Drug Evaluation, Preclinical; Female; Genes; Kidney Neoplasms; Mammary Neoplasms, Experimental; Mesocricetus; Methylnitrosourea; Mitochondria; Neoplasm Transplantation; Oxytetracycline; Rats; Rats, Inbred Strains; Tetracyclines; Time Factors

1984
Influence of the alkyllysophospholipid ET-18-OCH3 on methylnitrosourea-induced rat mammary carcinomas.
    Oncology, 1984, Volume: 41, Issue:2

    Topics: Animals; Antineoplastic Agents; Body Weight; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Lysophosphatidylcholines; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Phospholipid Ethers; Rats; Rats, Inbred Strains; Time Factors

1984
[Chronotherapy of breast cancer induced by N-nitrosomethylurea in the rat. I. Effect of a high dose of cyclophosphamide administered at 8:00 and 14:00 hours].
    Revista espanola de oncologia, 1984, Volume: 31, Issue:3

    Topics: Animals; Biotransformation; Circadian Rhythm; Cyclophosphamide; Drug Administration Schedule; Female; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1984
[Experimental toxicologic and therapeutic studies on the activity of the CMF(cyclophosphamide-methotrexate-5-fluorouracil) scheme versus the VMF(vincristine-methotrexate-5-fluorouracil) scheme].
    Archiv fur Geschwulstforschung, 1984, Volume: 54, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma 256, Walker; Cyclophosphamide; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Vincristine

1984
Chronochemotherapy of N-nitrosomethylurea-induced mammary tumors in rats. II. Circadian treatment with cyclophosphamide.
    Revista espanola de oncologia, 1984, Volume: 31, Issue:4

    Topics: Animals; Circadian Rhythm; Cyclophosphamide; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1984
[Treatment with intratumoral prospidium chloride of cancer of the mammae induced by N-nitrosomethylurea in the rat].
    Revista espanola de oncologia, 1984, Volume: 31, Issue:4

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Piperazines; Prospidium; Rats; Rats, Inbred Strains

1984
Mammary carcinogenesis in rats in relation to age at time of N-nitroso-N-methylurea administration.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:1

    Topics: Aging; Animals; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1983
Effect of duration of high fat intake on enhancement of mammary carcinogenesis in rats.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:1

    Topics: Animals; Cocarcinogenesis; Dietary Fats; Dose-Response Relationship, Drug; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Time Factors

1983
N-nitroso-N-methylurea-induced mammary carcinogenesis: effect of pregnancy on preneoplastic cells.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:3

    Topics: Animals; Female; Lactation; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Precancerous Conditions; Pregnancy; Pregnancy Complications, Neoplastic; Rats; Rats, Inbred Strains

1983
Regression of myelocytic leukemia in rats after hypophysectomy.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:2

    Topics: Animals; Hypophysectomy; Leukemia, Myeloid; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Rats

1984
Inhibition of mammary carcinogenesis by flurbiprofen, a non-steroidal antiinflammatory agent.
    British journal of cancer, 1983, Volume: 48, Issue:6

    Topics: Animals; Female; Flurbiprofen; Mammary Neoplasms, Experimental; Methylnitrosourea; Propionates; Rats; Rats, Inbred Strains; Time Factors

1983
Influence of cholera toxin on the growth and development of N-methyl-N-nitrosourea-induced rat mammary carcinomas.
    Cancer letters, 1983, Volume: 20, Issue:1

    Topics: Animals; Cell Division; Cholera Toxin; Diterpenes; Drug Interactions; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Retinyl Esters; Stimulation, Chemical; Vitamin A

1983
Assessment of mitogenesis of the hormone-responsive NMU rat mammary tumor grown in culture in soft agar, using 3H-thymidine incorporation into DNA.
    Breast cancer research and treatment, 1983, Volume: 3, Issue:3

    Topics: Animals; Cell Count; Cell Division; Cells, Cultured; DNA, Neoplasm; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitosis; Rats; Rats, Inbred Strains; Thymidine

1983
Effects of progesterone administration on N-nitrosomethylurea-induced rat mammary carcinogenesis.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:10

    Topics: Animals; Estrogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Pituitary Hormones, Anterior; Progesterone; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Time Factors

1983
[Estradiol receptors in the cytosol of nitrosomethylurea-induced mammary tumors of the rat. Influence of cell nuclei on the cytoplasmic estradiol receptor].
    Archiv fur Geschwulstforschung, 1984, Volume: 54, Issue:1

    Topics: Animals; Cell Nucleus; Cytoplasm; Cytosol; Estradiol; Female; Mammary Neoplasms, Experimental; Mesothelin; Methylnitrosourea; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Estradiol; Receptors, Estrogen; Temperature

1984
Effect of an inorganic and organic form of dietary selenium on the promotional stage of mammary carcinogenesis in the rat.
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Animals; Diet; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenomethionine; Time Factors

1984
Influence of estradiol and tamoxifen on the growth of N-nitrosomethylurea-induced rat mammary tumor cells in soft agar.
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Agar; Animals; Cell Division; Cell Survival; Cells, Cultured; Drug Antagonism; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tamoxifen

1984
Dietary vanadyl(IV) sulfate inhibits chemically-induced mammary carcinogenesis.
    Carcinogenesis, 1984, Volume: 5, Issue:6

    Topics: Animals; Diet; Female; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors; Vanadium; Vanadium Compounds

1984
Evaluation of new estrogen-linked 2-chloroethylnitrosoureas. I. Short term anticancer efficacy in methylnitrosourea-induced rat mammary carcinoma and hormonal activity in mice.
    Journal of cancer research and clinical oncology, 1984, Volume: 108, Issue:1

    Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Estrogens; Ethylnitrosourea; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Uterus

1984
Distribution of retinoic acid-binding proteins in normal and neoplastic mammary tissues.
    Cancer research, 1980, Volume: 40, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Binding, Competitive; Cytosol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Retinol-Binding Proteins; Tretinoin

1980
Inhibition of DNA synthesis by retinyl acetate during chemically induced mammary carcinogenesis.
    Cancer research, 1980, Volume: 40, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diterpenes; DNA, Neoplasm; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Retinyl Esters; Vitamin A

1980
N-methyl-N-nitrosourea-induced rat mammary tumors. Hormone responsiveness but lack of spontaneous metastasis.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Castration; Cytoplasm; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sebaceous Gland Neoplasms

1981
Response to ovariectomy of N-methyl-N-nitrosourea-induced mammary tumors in the rat.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:1

    Topics: Animals; Castration; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Nitrosourea Compounds; Prolactin; Rats; Receptors, Estrogen; Time Factors

1981
N-nitrosomethylurea-induced rat mammary tumours as models of human breast cancer.
    Journal of the Royal Society of Medicine, 1981, Volume: 74, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred WF

1981
[Influence of miskleron (clofibrate) on the carcinogenic effect of 7,12-dimethylbenz(alpha)anthracene and nitrosomethylurea in female rats].
    Voprosy onkologii, 1981, Volume: 27, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Clofibrate; Drug Interactions; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Time Factors

1981
Influence of lithium on mammary tumor growth in vivo.
    Cancer letters, 1980, Volume: 9, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Lithium; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Rats

1980
N-Nitroso-N-methylurea elicits mammary cancer in resistant and sensitive rat strains.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Resistance; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Species Specificity

1981
[Inhibition of the growth of 7,12-dimethylbenz(a)anthracene- and N-nitrosomethylurea-induced mammary gland neoplasms by methionine in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 91, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Female; Kidney Neoplasms; Leukemia, Experimental; Mammary Neoplasms, Experimental; Methionine; Methylnitrosourea; Nitrosourea Compounds; Rats; Sebaceous Gland Neoplasms

1981
Influence of prolactin and growth hormone on rat mammary tumors induced by N-nitrosomethylurea.
    Cancer research, 1982, Volume: 42, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Ergolines; Female; Growth Hormone; Hypophysectomy; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Pergolide; Prolactin; Rats

1982
Comparison of the effect of butylated hydroxytoluene on N-nitrosomethylurea and 7,12-dimethylbenz[a]-anthracene-induced mammary tumors.
    Cancer letters, 1981, Volume: 14, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Butylated Hydroxytoluene; Diet; Drug Interactions; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains

1981
Hormonal induction of casein gene expression limited to a small subpopulation of 7,12-dimethylbenz(a)anthracene-induced mammary tumor cells.
    Cancer research, 1982, Volume: 42, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caseins; Female; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Pregnancy; Rats; Rats, Inbred Strains; RNA, Messenger

1982
Effects of aromatase inhibitor 4-hydroxyandrostenedione and other compounds in the 7, 12-dimethylbenz(a)anthracene-induced breast carcinoma model.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Castration; Estrogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Ovary; Oxidoreductases; Rats

1982
Effects of isoproterenol on mammary gland tumors induced by N-nitroso-N-methylurea and salivary gland tumors induced by 7,12-dimethylbenz[a]anthracene.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Female; Isoproterenol; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Salivary Gland Neoplasms

1982
Inhibition by retinoid and ovariectomy of additional primary malignancies in rats following surgical removal of the first mammary cancer.
    Cancer, 1983, Feb-15, Volume: 51, Issue:4

    Topics: Animals; Castration; Diterpenes; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Multiple Primary; Rats; Rats, Inbred Strains; Retinyl Esters; Vitamin A

1983
Effects of different dietary fats on mammary carcinogenesis.
    Cancer research, 1983, Volume: 43, Issue:3

    Topics: Animals; Cocarcinogenesis; Dietary Fats; Fatty Acids; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Phospholipids; Rats; Rats, Inbred F344

1983
Induction of mammary gland carcinomas by the subcutaneous injection of 1-methyl-1-nitrosourea.
    Cancer research, 1983, Volume: 43, Issue:4

    Topics: Animals; Female; Injections, Intravenous; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains

1983
Effect of ovarian hormones on the induction of 1-methyl-1-nitrosourea-induced mammary cancer.
    Carcinogenesis, 1983, Volume: 4, Issue:4

    Topics: Animals; Drug Interactions; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Progesterone; Rats; Rats, Inbred Strains

1983
Effects of dietary fat on age-dependent sensitivity to mammary carcinogenesis.
    Cancer letters, 1983, Volume: 18, Issue:3

    Topics: Age Factors; Animals; Dietary Carbohydrates; Dietary Fats; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1983
Influence of thyroidectomy and prolactin suppression on the growth of N-nitrosomethylurea-induced rat mammary carcinomas.
    Cancer research, 1983, Volume: 43, Issue:6

    Topics: Animals; Ergolines; Female; Growth Hormone; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Pergolide; Prolactin; Rats; Rats, Inbred Strains; Thyroid Hormones; Thyroidectomy

1983
Noncarcinogenic chemotherapy with a combination of vincristine, methotrexate and 5-fluorouracil (VMF) in rats.
    International journal of cancer, 1983, Aug-15, Volume: 32, Issue:2

    Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors; Vincristine

1983
Induction of mammary tumors, estrous cycle abnormalities and endometrial hyperplasia in rats exposed to different doses of N-nitrosomethylurea.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:11

    Topics: Adenocarcinoma, Papillary; Animals; Dose-Response Relationship, Drug; Endometrial Hyperplasia; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone

1982
Synergistic effect of chronic prolactin suppression and retinoid treatment in the prophylaxis of N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats.
    Cancer research, 1980, Volume: 40, Issue:9

    Topics: Adrenal Glands; Animals; Depression, Chemical; Drug Synergism; Ergolines; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Organ Size; Ovary; Pituitary Gland; Prolactin; Rats; Time Factors; Tretinoin

1980
Effect of dietary fat on X-ray-induced mammary cancer in Sprague-Dawley rats.
    Journal of the National Cancer Institute, 1980, Volume: 64, Issue:3

    Topics: Animals; Cocarcinogenesis; Dietary Fats; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Multiple Primary; Neoplasms, Radiation-Induced; Rats; Time Factors; X-Rays

1980
Selenium inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis in the rat.
    Journal of the National Cancer Institute, 1980, Volume: 65, Issue:6

    Topics: Adenocarcinoma; Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Selenium; Time Factors

1980
Prostaglandin synthesis and binding is increased in regressing NMU mammary carcinoma.
    Prostaglandins, leukotrienes, and medicine, 1982, Volume: 8, Issue:3

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Prostaglandins; Rats

1982
Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Animals; Autoradiography; Basement Membrane; Breast Neoplasms; Cell Line; Collagen; Female; Fluorescent Antibody Technique; Humans; Hydroxyproline; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Proline; Protein Biosynthesis; Rats

1981
Carcinogenesis and aging. I. Modifying effects of aging on N-methyl-N-nitrosourea-induced carcinogenesis in female rats.
    Experimental pathology, 1981, Volume: 19, Issue:2

    Topics: Aging; Animals; Female; Kidney Neoplasms; Leukemia; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms; Nitrosourea Compounds; Rats; Thymoma; Uterine Cervical Neoplasms; Vaginal Neoplasms

1981
Inhibition of chemical carcinogenesis by retinoids.
    Journal of the American Academy of Dermatology, 1982, Volume: 6, Issue:4 Pt 2 Sup

    Topics: Animals; Castration; Esophageal Neoplasms; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Rats; Vitamin A

1982
Effects of hypothyroidism on development of nitrosomethylurea-induced tumors of the mammary gland, thyroid gland, and other tissues.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 169, Issue:4

    Topics: Animals; Female; Hypothyroidism; Kidney Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thyroid Neoplasms; Thyroxine; Triiodothyronine

1982
Spontaneously metastasizing variants derived from MNU-induced rat mammary tumour.
    British journal of cancer, 1982, Volume: 45, Issue:4

    Topics: Adenocarcinoma; Animals; Female; Lung Neoplasms; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Rats; Rats, Inbred F344; Receptors, Estrogen

1982
Influence of delayed administration of retinyl acetate on mammary carcinogenesis.
    Cancer research, 1982, Volume: 42, Issue:7

    Topics: Animals; Diterpenes; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Retinyl Esters; Time Factors; Vitamin A

1982
Isolation and characterization of a serially cultivated, neoplastic, epithelial cell line from the N-nitrosomethylurea induced rat mammary adenocarcinoma.
    In vitro, 1982, Volume: 18, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Line; Epithelium; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Nitrosourea Compounds; Rats

1982
[Induced resistance of experimental tumors to nitrosomethylurea].
    Voprosy onkologii, 1982, Volume: 28, Issue:11

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Resistance; Female; Kinetics; Mammary Neoplasms, Experimental; Melphalan; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasm Transplantation; Nitrosourea Compounds

1982
Dietary cholesterol and experimental mammary cancer development.
    Nutrition and cancer, 1982, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Animals; Cholesterol, Dietary; Dietary Fats; Drug Synergism; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred F344; Triglycerides

1982
Intensity of proliferation and sensitivity of experimental tumors to the 1-methyl-1-nitrosourea.
    Neoplasma, 1982, Volume: 29, Issue:5

    Topics: Animals; Cell Division; DNA, Neoplasm; Kinetics; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Neoplasm Transplantation; Nitrosourea Compounds

1982
Inhibition of 1-methyl-1-nitrosourea-induced mammary carcinogenesis in the rat by the retinoid axerophthene.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:7

    Topics: Animals; Body Weight; Diet; Diterpenes; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Time Factors; Vitamin A

1980
Effect of combined selenium and retinyl acetate treatment on mammary carcinogenesis.
    Cancer research, 1981, Volume: 41, Issue:4

    Topics: Analysis of Variance; Animals; Body Weight; Diet; Diterpenes; Drug Synergism; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Pregnancy; Rats; Retinyl Esters; Selenium; Time Factors; Vitamin A

1981
Influence of the estrous cycle during carcinogen exposure on nitrosomethylurea-induced rat mammary carcinoma.
    Cancer research, 1981, Volume: 41, Issue:10

    Topics: Adenocarcinoma; Animals; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred BUF; Receptors, Estrogen; Receptors, Progesterone; Time Factors

1981
Activity of the antioestrogen trioxifene against N-Nitrosomethylurea-induced rat mammary carcinomas.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:8

    Topics: Animals; Antineoplastic Agents; Castration; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen

1981
Hormone dependence of rat mammary tumors induced by N- nitrosomethylurea.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:12

    Topics: Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Nitrosourea Compounds; Prolactin; Rats; Rats, Inbred Strains

1981
Lifetime dose-response relationships for mammary tumor induction by a single administration of N-methyl-N-nitrosourea.
    Cancer research, 1981, Volume: 41, Issue:5

    Topics: Adenocarcinoma; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Kidney Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Sarcoma, Experimental

1981
Studies with 17 beta(16 alpha-[125i]iodo)-estradiol, an estrogen receptor-binding radiopharmaceutical, in rats bearing mammary tumors.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1981, Volume: 22, Issue:5

    Topics: Adenocarcinoma; Adrenal Glands; Animals; Bile; Diethylstilbestrol; Estradiol; Female; Iodine Radioisotopes; Liver; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Radionuclide Imaging; Rats; Receptors, Estrogen; Tissue Distribution; Uterus

1981
Pathology of metastasizing tumors in nitrosomethyl urea-induced rat mammary carcinoma.
    Journal of surgical oncology, 1981, Volume: 18, Issue:1

    Topics: Adenocarcinoma; Animals; Female; Liver Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Nitrosourea Compounds; Rats; Rats, Inbred BUF; Splenic Neoplasms

1981
Structural alterations within N-nitrosomethylurea-induced mammary tumors after in vivo treatment with cis-hydroxyproline.
    Laboratory investigation; a journal of technical methods and pathology, 1981, Volume: 45, Issue:4

    Topics: Animals; Basement Membrane; Collagen; Female; Hydroxyproline; Mammary Neoplasms, Experimental; Mast Cells; Methylnitrosourea; Rabbits; Rats; Rats, Inbred Strains

1981
The influence of sodium selenite on tumor induction by methylnitrosourea (MNU) in rats.
    Archiv fur Geschwulstforschung, 1981, Volume: 51, Issue:6

    Topics: Animals; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenious Acid; Selenium

1981
Influence of dosage schedule on the biological characteristics of N-nitrosomethylurea-induced rat mammary tumors.
    Cancer research, 1980, Volume: 40, Issue:2

    Topics: Animals; Castration; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Receptors, Estrogen; Remission, Spontaneous; Tamoxifen; Time Factors

1980
[Mammary gland tumor induction in rats by N-nitroso-N-methylurea and N-methyl-N1-nitro-N-nitrosoguanidine].
    Voprosy onkologii, 1980, Volume: 26, Issue:2

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Methylnitrosourea; Nitrosourea Compounds; Rats; Time Factors

1980
Induction of breast cancer by nitrosomethylurea in rats of the Buffalo strain: frequent association with thyroid disease.
    Endocrinology, 1980, Volume: 107, Issue:4

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Rats; Species Specificity; Thyroid Diseases; Thyroid Gland; Thyrotropin

1980
Ultrastructure of the hormone-dependent N-nitrosomethylurea-induced mammary carcinoma of the rat.
    Cancer research, 1980, Volume: 40, Issue:9

    Topics: Adenocarcinoma; Animals; Carcinoma, Papillary; Castration; Epithelium; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Microscopy, Electron; Necrosis; Neoplasms, Hormone-Dependent; Rats

1980
Enhancement of mammary carcinogenesis by a high-fat diet in Fischer, Long-Evans, and Sprague-Dawley rats.
    Cancer research, 1981, Volume: 41, Issue:1

    Topics: Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Species Specificity

1981
The effect of endocrine therapy on fibroblast growth factor-like activity in nitrosomethylurea-induced rat mammary tumours.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:15

    Topics: Animals; Culture Media; Doxorubicin; Female; Fibroblast Growth Factor 1; Heparin; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Tumor Cells, Cultured

1993
Lipotrope-modified diets enhance nitrosomethylurea-induced mammary carcinogenesis in female rats.
    Nutrition and cancer, 1993, Volume: 20, Issue:3

    Topics: Animals; Drug Synergism; Female; Lipotropic Agents; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1993
Hormonal regulation of insulin-like growth factor II and insulin-like growth factor binding protein expression by breast cancer cells in vivo: evidence for stromal epithelial interactions.
    Cancer research, 1994, Jun-01, Volume: 54, Issue:11

    Topics: Animals; Carrier Proteins; Female; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor Binding Protein 6; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor II; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Sprague-Dawley; RNA, Messenger

1994
Deregulated expression of cyclin D1 and other cell cycle-related genes in carcinogen-induced rat mammary tumors.
    Carcinogenesis, 1995, Volume: 16, Issue:9

    Topics: Animals; Carcinogens; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; Cystadenocarcinoma, Papillary; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Mammary Neoplasms, Experimental; Methylnitrosourea; Oncogene Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley

1995
Rapid induction of mammary intraductal proliferations, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: Aging; Animals; Carcinogens; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cell Division; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Sexual Maturation

1995
Refractoriness to mammary tumorigenesis in parous rats: is it caused by persistent changes in the hormonal environment or permanent biochemical alterations in the mammary epithelia?
    Carcinogenesis, 1995, Volume: 16, Issue:11

    Topics: Animals; ErbB Receptors; Female; Growth Hormone; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Parity; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Estrogen

1995
ras may mediate mammary cancer promotion by high fat.
    Nutrition and cancer, 1995, Volume: 23, Issue:3

    Topics: Adenocarcinoma; Animals; Base Sequence; Codon; Corn Oil; Dietary Fats; Female; Fish Oils; Genes, ras; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley

1995
H1 and H2 histamine receptors in N-nitroso-N-methylurea (NMU)-induced carcinomas with atypical coupling to signal transducers.
    Biochemical pharmacology, 1995, Jun-29, Volume: 50, Issue:1

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H2; Signal Transduction

1995
Protection by grafts of embryonal rat tissues (teratomas) against induction and transplantation of malignant tumors.
    Cancer research, 1995, Aug-15, Volume: 55, Issue:16

    Topics: Animals; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rats; Rats, Inbred BUF; Rats, Sprague-Dawley; Teratoma

1995
Prolactin is a local growth factor in rat mammary tumors.
    Endocrinology, 1995, Volume: 136, Issue:8

    Topics: Animals; Base Sequence; Cell Division; Female; Growth Substances; Immune Sera; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Probes; Molecular Sequence Data; Prolactin; Rats; Receptors, Prolactin

1995
Exercise intensity dependent inhibition of 1-methyl-1-nitrosourea induced mammary carcinogenesis in female F-344 rats.
    Carcinogenesis, 1995, Volume: 16, Issue:8

    Topics: Animals; Energy Metabolism; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Conditioning, Animal; Rats; Rats, Inbred F344

1995
Silicone implants and the inhibition of cancer.
    Plastic and reconstructive surgery, 1995, Volume: 96, Issue:3

    Topics: Age Factors; Animals; Back; Breast Implants; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Peritoneal Cavity; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Silicones

1995
Effect of dietary fatty acids on gene expression in breast cells.
    Advances in experimental medicine and biology, 1995, Volume: 375

    Topics: Animals; Dietary Fats; DNA; Fatty Acids; Female; Gene Expression; Genes, ras; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1995
Effect of high-dose, fractionated local irradiation on MNU-induced carcinogenesis in the rat mammary gland.
    Carcinogenesis, 1995, Volume: 16, Issue:3

    Topics: Animals; Breast; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Radiation-Induced; Radiotherapy; Radiotherapy Dosage; Rats; Rats, Sprague-Dawley

1995
Effectiveness of delta-aminolevulinic acid-induced protoporphyrin as a photosensitizer for photodynamic therapy in vivo.
    Cancer research, 1995, Apr-15, Volume: 55, Issue:8

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Division; Chromatography, High Pressure Liquid; Female; Kinetics; Light; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Photochemotherapy; Porphyrins; Protoporphyrins; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tissue Distribution

1995
Enhancement by chronic ethanol intake of N-methyl-N-nitrosourea-induced rat mammary tumorigenesis.
    Carcinogenesis, 1995, Volume: 16, Issue:4

    Topics: Alcohol Drinking; Animals; Cocarcinogenesis; Drug Synergism; Ethanol; Evaluation Studies as Topic; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1995
Refractoriness to mammary carcinogenesis in the parous mouse is reversible by hormonal stimulation induced by pituitary isografts.
    Cancer letters, 1995, Apr-14, Volume: 90, Issue:2

    Topics: Adenocarcinoma; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Disease Susceptibility; Female; Humans; Infant, Newborn; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mitogens; Parity; Pituitary Gland; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy, Animal; Progesterone; Prolactin

1995
[Effects of light deprivation on carcinogenesis induced by N-nitrosomethylurea in female rats].
    Voprosy onkologii, 1994, Volume: 40, Issue:1-3

    Topics: Adenocarcinoma; Adenoma; Animals; Blindness; Female; Fibroadenoma; Leukemia, Experimental; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Pineal Gland; Pituitary Neoplasms; Rats; Thyroid Neoplasms; Time Factors

1994
Induction of mammary carcinomas by the direct application of crystalline N-methyl-N-nitrosourea onto rat mammary gland.
    Cancer letters, 1995, May-25, Volume: 92, Issue:1

    Topics: Adenocarcinoma; Animals; Crystallization; Female; Immunohistochemistry; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1995
Loss of heterozygosity at chromosome 1q loci in rat mammary tumors.
    Molecular carcinogenesis, 1995, Volume: 12, Issue:1

    Topics: Adenocarcinoma; Animals; Chromosome Deletion; Chromosome Mapping; Female; Genes, ras; Heterozygote; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Polymorphism, Genetic; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred BUF; Rats, Inbred Lew

1995
A histopathological study on alterations in DMBA-induced mammary carcinogenesis in rats with 50 Hz, 100 muT magnetic field exposure.
    Carcinogenesis, 1995, Volume: 16, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Behavior, Animal; Cocarcinogenesis; Electromagnetic Fields; Female; Hyperplasia; Magnetics; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1995
Influence of ethanol intake on mammary gland morphology and cell proliferation in normal and carcinogen-treated rats.
    Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:5

    Topics: Alcohol Drinking; Animals; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Replication; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Rats; Rats, Sprague-Dawley

1994
Histamine receptors in an experimental mammary carcinoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1994, Volume: 48, Issue:8-9

    Topics: Animals; Carcinoma; Cyclic AMP; Histamine Antagonists; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Histamine

1994
Inhibition of mammary carcinogenesis by treadmill exercise.
    Journal of the National Cancer Institute, 1995, Mar-15, Volume: 87, Issue:6

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Conditioning, Animal; Random Allocation; Rats; Rats, Inbred F344

1995
Evidence that carcinogenesis involves an imbalance between epigenetic high-frequency initiation and suppression of promotion.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Feb-28, Volume: 92, Issue:5

    Topics: Adenocarcinoma; Animals; Carcinogens; Clone Cells; Female; Gamma Rays; Genes, Tumor Suppressor; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Radiation-Induced; Prolactin; Rats; Rats, Inbred F344

1995
Prolactin-immune interactions in carcinogen-induced rat mammary tumors.
    Endocrine research, 1994, Volume: 20, Issue:4

    Topics: Animals; Carcinogens; Cells, Cultured; Concanavalin A; Female; Growth Hormone; Interleukin-2; Lymphocytes; Mammary Neoplasms, Experimental; Methylnitrosourea; Pituitary Gland; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-2; Time Factors

1994
Chromatographic investigations of estradiol receptor from breast cancer tissue.
    Folia biologica, 1993, Volume: 39, Issue:6

    Topics: Animals; Breast Neoplasms; Chromatography, Ion Exchange; Ethanolamines; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Receptors, Estradiol

1993
Identification of a mammary transforming gene (MAT1) associated with mouse mammary carcinogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-11, Volume: 91, Issue:21

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Transformation, Neoplastic; Genes, ras; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasm Proteins; Point Mutation

1994
Immunocytochemical localization of estrogen receptors in the mammary tissue of female rats: relevance to carcinogenesis.
    Progress in clinical and biological research, 1994, Volume: 387

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antibodies, Monoclonal; Estrogens; Feasibility Studies; Female; Immunohistochemistry; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Rats; Rats, Sprague-Dawley; Receptors, Estrogen

1994
Induction of mammary tumors in rat by intraperitoneal injection of NMU: histopathology and estral cycle influence.
    Cancer letters, 1994, Nov-11, Volume: 86, Issue:2

    Topics: Animals; Estrus; Female; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1994
An overexpressed N-ras proto-oncogene cooperates with N-methylnitrosourea in mouse mammary carcinogenesis.
    Cancer research, 1994, Dec-15, Volume: 54, Issue:24

    Topics: Animals; Base Sequence; Genes, ras; Lymphoma; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Molecular Sequence Data; Point Mutation; Polymorphism, Restriction Fragment Length; Proto-Oncogene Mas; Sodium Chloride

1994
Chemopreventive effects of the aromatase inhibitors vorozole (R-83842) and 4-hydroxyandrostenedione in the methylnitrosourea (MNU)-induced mammary tumor model in Sprague-Dawley rats.
    Carcinogenesis, 1994, Volume: 15, Issue:12

    Topics: Adenocarcinoma; Aminoglutethimide; Androstenedione; Animals; Anticarcinogenic Agents; Aromatase Inhibitors; Drug Screening Assays, Antitumor; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazoles

1994
Activity of triphenylselenonium chloride in mammary cancer prevention.
    Carcinogenesis, 1994, Volume: 15, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Tissue Distribution

1994
Limonene chemoprevention of mammary carcinoma induction following direct in situ transfer of v-Ha-ras.
    Cancer research, 1994, Jul-01, Volume: 54, Issue:13

    Topics: Animals; beta-Galactosidase; Cyclohexenes; Drug Screening Assays, Antitumor; Female; Genes, ras; Limonene; Mammary Neoplasms, Experimental; Methylnitrosourea; Random Allocation; Rats; Rats, Wistar; Terpenes; Transfection

1994
Metabolic consequences of a reversed pH gradient in rat tumors.
    Cancer research, 1994, Aug-01, Volume: 54, Issue:15

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carbonates; Cell Membrane Permeability; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Liver Neoplasms, Experimental; Magnesium; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Methylnitrosourea; NAD; Phosphorus; Potassium; Rats; Rats, Inbred BUF; Rats, Wistar; Sarcoma, Experimental; Sodium

1994
Pituitary-isografted mice are highly susceptible to MNU-induced mammary carcinogenesis irrespective of the level of alveolar differentiation.
    Carcinogenesis, 1994, Volume: 15, Issue:7

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Pituitary Gland; Transplantation, Heterotopic; Transplantation, Isogeneic

1994
[Inhibition of mammary gland carcinogenesis using a tincture from biomass of ginseng tissue culture].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 115, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cells, Cultured; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Panax; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar

1993
Effect of excess dietary iron on the promotion stage of 1-methyl-1-nitrosourea-induced mammary carcinogenesis: pathogenetic characteristics and distribution of iron.
    Carcinogenesis, 1994, Volume: 15, Issue:8

    Topics: Animals; Diet; Female; Iron; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1994
Inhibition of carcinogen-induced pulmonary and mammary carcinogenesis by chalcone administered subsequent to carcinogen exposure.
    Cancer letters, 1994, Aug-15, Volume: 83, Issue:1-2

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Chalcone; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred A; Rats; Rats, Sprague-Dawley; Stomach Neoplasms

1994
Prevention of breast cancer in the rat with 9-cis-retinoic acid as a single agent and in combination with tamoxifen.
    Cancer research, 1994, Sep-01, Volume: 54, Issue:17

    Topics: Animals; Breast Neoplasms; Drug Screening Assays, Antitumor; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen; Tretinoin; Tumor Cells, Cultured

1994
Pharmacokinetic behavior and antineoplastic activity of liposomal hexadecylphosphocholine.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Chromatography, High Pressure Liquid; Drug Carriers; Female; Half-Life; Injections, Intravenous; Liposomes; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Rats, Wistar

1994
Interactions between 4-HPR and diet in NMU-induced mammary tumorigenesis.
    Nutrition and cancer, 1994, Volume: 21, Issue:3

    Topics: Animals; Diet; Edible Grain; Female; Fenretinide; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred F344; Weight Gain

1994
[Modifying effect of light and electromagnetic field on development of mammary tumors induced by N-nitrosomethyl urea in female rats].
    Voprosy onkologii, 1993, Volume: 39, Issue:1-3

    Topics: Animals; Darkness; Electromagnetic Fields; Female; Lighting; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Prolactin; Rats

1993
In vitro carcinogenesis of mammary epithelial cells by N-nitroso-N-methylurea using a collagen gel matrix culture.
    In vitro cellular & developmental biology. Animal, 1993, Volume: 29A, Issue:10

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1993
Comparison of O6-methylguanine-DNA methyltransferase mRNA levels in Ha-ras mutated and non-mutated rat mammary tumors induced by N-methyl-N-nitrosourea.
    Carcinogenesis, 1994, Volume: 15, Issue:3

    Topics: Animals; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger

1994
1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol (Ro24-5531), a new deltanoid (vitamin D analogue) for prevention of breast cancer in the rat.
    Cancer research, 1994, Apr-01, Volume: 54, Issue:7

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Breast Neoplasms; Calcitriol; Calcium; Cell Division; Cell Line; Diet; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Invasiveness; Rats; Rats, Sprague-Dawley; Tamoxifen; Tumor Cells, Cultured

1994
N-nitroso-N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogenic Hras1 gene mutations.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Apr-26, Volume: 91, Issue:9

    Topics: Animals; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Oncogenes; Rats; Rats, Inbred F344

1994
Effectiveness of combined limonene and 4-hydroxyandrostenedione in the treatment of NMU-induced rat mammary tumours.
    British journal of cancer, 1994, Volume: 69, Issue:5

    Topics: Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclohexenes; Drug Screening Assays, Antitumor; Female; Limonene; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Terpenes

1994
Inhibition of mammary tumors by pretreatment with 17 beta-estradiol in F344 rats induced with N-methyl-N-nitrosourea.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:3

    Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Rats; Rats, Inbred F344

1994
Systematic HRAS amplification in ovary-independent mammary tumors: correlation with progressively anaplastic phenotypes.
    Cancer research, 1993, Nov-15, Volume: 53, Issue:22

    Topics: Adenocarcinoma; Alleles; Animals; Antigens, Neoplasm; Carcinoma; Chromosome Banding; DNA, Neoplasm; Female; Gene Amplification; Genes, ras; In Situ Hybridization; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenotype; Rats; Rats, Inbred BUF

1993
Dietary restriction reduces the incidence of NMU-induced mammary tumors and alters retinoid tissue concentrations in rats.
    Nutrition and cancer, 1993, Volume: 20, Issue:2

    Topics: Adipose Tissue; Animals; Chi-Square Distribution; Diet, Reducing; Female; Intestinal Mucosa; Intestines; Kidney; Liver; Lung; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution; Vitamin A; Weight Gain

1993
Estrous cycle modulation of O6-alkylguanine-DNA alkyltransferase expression in rat mammary epithelial cells.
    Cancer letters, 1993, Nov-30, Volume: 75, Issue:1

    Topics: Animals; Base Sequence; Epithelium; Estrus; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Sprague-Dawley; RNA, Messenger

1993
Absence of MDM-2 gene amplification in experimentally induced tumors regardless of p53 status.
    Molecular carcinogenesis, 1994, Volume: 9, Issue:1

    Topics: Animals; Base Sequence; Female; Gene Amplification; Genes, p53; Harderian Gland; Hyperplasia; Lymphoma; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred DBA; Mice, Transgenic; Molecular Sequence Data; Neoplasm Proteins; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Thymus Neoplasms

1994
Effect of varying proportions of dietary menhaden and corn oil on experimental rat mammary tumor promotion.
    Lipids, 1993, Volume: 28, Issue:5

    Topics: Adenocarcinoma; Adenofibroma; Animals; Cholesterol; Corn Oil; Dietary Fats, Unsaturated; Fatty Acids; Fatty Acids, Unsaturated; Female; Fish Oils; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred F344

1993
Demonstration of a 65 kDa tumor-specific phosphoprotein in urine and serum of rats with N-methyl-N-nitrosourea-induced mammary adenocarcinomas.
    Carcinogenesis, 1993, Volume: 14, Issue:8

    Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Female; Immunoblotting; Isoelectric Focusing; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphoproteins; Phosphorylation; Precipitin Tests; Rats; Rats, Sprague-Dawley

1993
Hexadecylphosphocholine differs from conventional cytostatic agents.
    Journal of cancer research and clinical oncology, 1993, Volume: 119, Issue:9

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Chromatography, High Pressure Liquid; DNA, Viral; Dose-Response Relationship, Drug; Herpes Simplex; Mammary Neoplasms, Experimental; Methylnitrosourea; Nucleotides; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Simplexvirus; Vesicular stomatitis Indiana virus; Virus Diseases; Virus Replication

1993
Effect of conjoint administration of tamoxifen and high-dose radiation on the development of mammary carcinoma.
    International journal of radiation oncology, biology, physics, 1993, Apr-30, Volume: 26, Issue:1

    Topics: Animals; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen

1993
Effect of retinoic acid (RA) in MNU-induced rat mammary tumors.
    Annals of the New York Academy of Sciences, 1995, Sep-30, Volume: 768

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Sprague-Dawley; Tamoxifen; Tretinoin

1995
Inhibition of rat mammary tumorigenesis by dietary cholesterol.
    Carcinogenesis, 1996, Volume: 17, Issue:1

    Topics: Animals; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

1996
Dose-response effects of dietary fiber on NMU-induced mammary tumorigenesis, estrogen levels and estrogen excretion in female rats.
    Carcinogenesis, 1996, Volume: 17, Issue:1

    Topics: Animals; Cellulose; Dietary Fiber; Dose-Response Relationship, Drug; Estrogens; Feces; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred F344; Triticum

1996
Overexpression of neu-related lipocalin (NRL) in neu-initiated but not ras or chemically initiated rat mammary carcinomas.
    Oncogene, 1995, Dec-07, Volume: 11, Issue:11

    Topics: Amino Acid Sequence; Animals; Antibody Formation; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Electrophoresis, Gel, Two-Dimensional; Female; Genes, erbB-2; Genes, ras; Lipocalin-2; Lipocalins; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Protein Biosynthesis; Rabbits; Rats; Rats, Wistar; Sequence Homology, Amino Acid

1995
Regulation of cytochromes P450 by DHEA and its anticarcinogenic action.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 774

    Topics: Animals; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Liver; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Nafenopin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Triiodothyronine

1995
Effects of dehydroepiandrosterone on MNU-induced breast cancer in Sprague-Dawley rats.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 774

    Topics: Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Female; Liver Neoplasms; Mammary Neoplasms, Experimental; Methylnitrosourea; Microbodies; Rats; Rats, Sprague-Dawley

1995
N-Ethyl-N-nitrosourea induces mammary cancers in the pituitary-isografted mouse which are histologically and genotypically distinct from those induced by N-methyl-N-nitrosourea.
    Cancer letters, 1996, Apr-19, Volume: 102, Issue:1-2

    Topics: Animals; Base Sequence; Carcinogens; Cocarcinogenesis; Ethylnitrosourea; Female; Gene Expression Regulation, Neoplastic; Genotype; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Pituitary Gland, Anterior; Structure-Activity Relationship; Transplantation, Isogeneic

1996
Garlic and associated allyl sulfur components inhibit N-methyl-N-nitrosourea induced rat mammary carcinogenesis.
    Cancer letters, 1996, Apr-19, Volume: 102, Issue:1-2

    Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Carcinogens; Cysteine; Disulfides; Eating; Female; Garlic; Mammary Neoplasms, Experimental; Methylnitrosourea; Plant Oils; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Weight Gain

1996
Effect of timing and duration of dietary conjugated linoleic acid on mammary cancer prevention.
    Nutrition and cancer, 1995, Volume: 24, Issue:3

    Topics: Animals; Dietary Fats, Unsaturated; Female; Linoleic Acid; Linoleic Acids; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Triglycerides

1995
Time-course study of adipose tissue fatty acid composition during mammary tumor growth in rats with controlled fat intake.
    Nutrition and cancer, 1995, Volume: 24, Issue:3

    Topics: Adipose Tissue; alpha-Linolenic Acid; Animals; Dietary Fats; Fatty Acids; Female; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Triglycerides

1995
Cyclic food restriction alters substrate utilization and abolishes protection from mammary carcinogenesis female rats.
    The Journal of nutrition, 1996, Volume: 126, Issue:5

    Topics: Adipose Tissue; Animals; Body Weight; Calorimetry, Indirect; Carcinogens; Diet; Eating; Energy Metabolism; Fatty Acids; Female; Glucose; Incidence; Lipid Metabolism; Mammary Neoplasms, Experimental; Methylnitrosourea; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors

1996
Effect of tamoxifen on intraperitoneal N-nitroso-N-methylurea induced tumors.
    Cancer letters, 1996, Feb-27, Volume: 100, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Hormonal; Carcinogens; Estrogen Antagonists; Female; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen

1996
Exceptional chemopreventive activity of low-dose dehydroepiandrosterone in the rat mammary gland.
    Cancer research, 1996, Apr-15, Volume: 56, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Carbenoxolone; Carcinogens; Dehydroepiandrosterone; Diet; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen

1996
Receptors characterization of intraperitoneally N-nitroso-N-methylurea-induced mammary tumors in rats.
    Cancer letters, 1996, Mar-19, Volume: 101, Issue:1

    Topics: Animals; Carcinogens; Carcinoma, Ductal, Breast; ErbB Receptors; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin

1996
Hormone dependent and independent mammary tumor development form N-methyl-N-nitrosourea-treated rat mammary epithelial cell xenografts in the nude mouse: multiple pathways and H-ras activation.
    Cancer letters, 1996, Mar-19, Volume: 101, Issue:1

    Topics: Adenocarcinoma; Animals; Base Sequence; Carcinogens; Cocarcinogenesis; Disease Models, Animal; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Point Mutation; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Transplantation, Heterologous

1996
Alteration of gene expression in rat mammary tumors induced by N-methyl-N-nitrosourea.
    Molecular carcinogenesis, 1996, Volume: 15, Issue:4

    Topics: Alkylating Agents; Animals; Base Sequence; Carcinogens; Cloning, Molecular; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Neoplasm

1996
Wheat bran and psyllium diets: effects on N-methylnitrosourea-induced mammary tumorigenesis in F344 rats.
    Journal of the National Cancer Institute, 1996, Jul-03, Volume: 88, Issue:13

    Topics: Animals; Cecum; Dietary Fiber; Dose-Response Relationship, Drug; Estrogens; Female; Glucuronidase; Mammary Neoplasms, Experimental; Methylnitrosourea; Psyllium; Radioimmunoassay; Random Allocation; Rats; Rats, Inbred F344; Weight Gain

1996
Detection of breast cancer-associated estrone sulfatase in breast cancer biopsies and cell lines using polymerase chain reaction.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:2

    Topics: Animals; Antineoplastic Agents, Hormonal; Base Sequence; Biopsy; Blotting, Northern; Breast Neoplasms; Carcinogens; DNA Primers; DNA, Complementary; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Polymerase Chain Reaction; Rats; RNA, Neoplasm; Sulfatases; Tamoxifen; Tumor Cells, Cultured

1993
Histamine regulates the expression of histidine decarboxylase in N-nitroso-N-methylurea (NMU)-induced mammary tumors in rats.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45 Suppl 1

    Topics: Analysis of Variance; Animals; Blotting, Northern; Carcinogens; DNA, Complementary; Female; Gene Expression Regulation, Enzymologic; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine Decarboxylase; Kidney; Mammary Neoplasms, Experimental; Methylhistidines; Methylnitrosourea; Rats; RNA, Messenger; Uterus

1996
The effect of dietary fat on the promotion of mammary and colon cancer in a dual-organ rat carcinogenesis model.
    Nutrition and cancer, 1996, Volume: 25, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Time Factors

1996
Exercise during adolescence and its effects on mammary gland development, proliferation, and nitrosomethylurea (NMU) induced tumorigenesis in rats.
    Breast cancer research and treatment, 1996, Volume: 37, Issue:1

    Topics: Age Factors; Animals; Cell Division; Disease Models, Animal; Female; Incidence; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley

1996
Absence of p53 mutations in methylnitrosourea-induced mammary tumors in rats.
    Cancer detection and prevention, 1996, Volume: 20, Issue:3

    Topics: Animals; Female; Genes, p53; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Rats; Rats, Inbred F344

1996
Effect on an aqueous extract of selenium-enriched garlic on in vitro markers and in vivo efficacy in cancer prevention.
    Carcinogenesis, 1996, Volume: 17, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Cycle; Cell Division; Cysteine; DNA Damage; DNA, Neoplasm; Female; Freeze Drying; Garlic; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Organoselenium Compounds; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Sodium Selenite

1996
Selenium-enriched garlic inhibits the early stage but not the late stage of mammary carcinogenesis.
    Carcinogenesis, 1996, Volume: 17, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Female; Food, Fortified; Garlic; Kidney; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Staging; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Selenium; Tissue Distribution

1996
Incidence of p53 and Ha-ras gene mutations in chemically induced rat mammary carcinomas.
    Molecular carcinogenesis, 1996, Volume: 17, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA, Neoplasm; Female; Genes, p53; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Sprague-Dawley; Species Specificity

1996
Alterations in H-ras1 promoter conformation during N-nitroso-N-methylurea-induced mammary carcinogenesis and pregnancy.
    Cancer research, 1996, Nov-01, Volume: 56, Issue:21

    Topics: Animals; Carcinogens; DNA Methylation; DNA, Neoplasm; Female; Genes, ras; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Nucleic Acid Conformation; Polymerase Chain Reaction; Pregnancy; Pregnancy, Animal; Promoter Regions, Genetic; Rats; Rats, Inbred F344

1996
Evidence of in situ estrogen synthesis in nitrosomethylurea-induced rat mammary tumors via the enzyme estrone sulfatase.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:4

    Topics: Animals; Estrogens; Estrone; Female; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Sulfatases

1996
Midkine in the progression of rat N-nitroso-N-methylurea-induced mammary tumors.
    Molecular carcinogenesis, 1996, Volume: 17, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinogens; Carrier Proteins; Cell Differentiation; Cytokines; Disease Progression; Gene Expression; Mammary Neoplasms, Experimental; Methylnitrosourea; Midkine; Rats; Rats, Inbred BUF; RNA, Messenger; Tretinoin; Tumor Cells, Cultured

1996
Ha-ras-1 oncogene mutations in mammary epithelial cells do not contribute to initiation of spontaneous mammary tumorigenesis in rats.
    Carcinogenesis, 1996, Volume: 17, Issue:11

    Topics: Animals; Carcinogens; Cell Division; Codon; DNA Mutational Analysis; Epithelial Cells; Epithelium; Female; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Rats; Rats, Inbred F344

1996
Chemoprevention of mammary carcinoma by LGD1069 (Targretin): an RXR-selective ligand.
    Cancer research, 1996, Dec-15, Volume: 56, Issue:24

    Topics: Animals; Anticarcinogenic Agents; Bexarotene; Carcinogens; Drug Screening Assays, Antitumor; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoid X Receptors; Tetrahydronaphthalenes; Transcription Factors; Uterus

1996
Sulfone metabolite of sulindac inhibits mammary carcinogenesis.
    Cancer research, 1997, Jan-15, Volume: 57, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Drug Screening Assays, Antitumor; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Sulindac

1997
Combination of melatonin and tamoxifen as a chemoprophylaxis against N-nitroso-N-methylurea-induced rat mammary tumors.
    Cancer letters, 1997, Jan-01, Volume: 111, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen

1997
Hormone dependence of mammary tumors induced in rats by intraperitoneal NMU injection.
    Cancer investigation, 1997, Volume: 15, Issue:1

    Topics: Animals; Bromocriptine; Carcinogens; Estradiol; Female; Haloperidol; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Ovariectomy; Progesterone; Prolactin; Rats; Rats, Sprague-Dawley; Tamoxifen

1997
Retinyl ethers as cancer chemopreventive agents. Suppression of mammary cancer.
    Anti-cancer drug design, 1997, Volume: 12, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Drug Screening Assays, Antitumor; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Vitamin A

1997
Resistance to chemically-induced mammary tumors in Copenhagen X nude-derived F2 athymic rats: evidence that T-cell immunity is not involved in Copenhagen resistance.
    Carcinogenesis, 1997, Volume: 18, Issue:1

    Topics: Animals; Carcinogens; Crosses, Genetic; Drug Resistance; Female; Genotype; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Nude; T-Lymphocytes, Cytotoxic

1997
Fluoromethylhistidine inhibits tumor growth without producing depletion of endogenous histamine.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46 Suppl 1

    Topics: Animals; Carcinogens; Enzyme Inhibitors; Female; Histamine; Histidine Decarboxylase; Mammary Neoplasms, Experimental; Methylhistidines; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1997
Energy availability and mammary carcinogenesis: effects of calorie restriction and exercise.
    Carcinogenesis, 1997, Volume: 18, Issue:6

    Topics: Adrenal Cortex Hormones; Animals; Carcinogens; Energy Intake; Energy Metabolism; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Conditioning, Animal; Rats; Rats, Inbred F344

1997
Inhibition of mammary carcinogenesis in rats by parenteral high-dose vitamin E.
    Journal of the National Cancer Institute, 1997, Jul-02, Volume: 89, Issue:13

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Carcinoma, Papillary; Female; Infusions, Parenteral; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Vitamin E

1997
Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid.
    Cancer research, 1997, Aug-15, Volume: 57, Issue:16

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carcinogens; Drug Screening Assays, Antitumor; Enzyme Induction; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Rats; Rats, Sprague-Dawley; Skin Neoplasms

1997
Fasting during promotion, but not during initiation, enhances the growth of methylnitrosourea-induced mammary tumours.
    Carcinogenesis, 1997, Volume: 18, Issue:8

    Topics: Adenocarcinoma; Animals; Body Weight; Fasting; Female; Kidney Neoplasms; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovarian Neoplasms; Rats; Rats, Sprague-Dawley; Uterine Neoplasms

1997
Idoxifene is equipotent to tamoxifen in inhibiting mammary carcinogenesis but forms lower levels of hepatic DNA adducts.
    British journal of cancer, 1997, Volume: 76, Issue:6

    Topics: Animals; DNA Adducts; Female; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Survival Analysis; Tamoxifen; Time Factors

1997
Pirocarbotrat: a new radiopharmaceutical for the treatment of solid tumors--comparative studies in N-nitrosomethylurea-induced rat mammary tumors.
    Nuclear medicine and biology, 1997, Volume: 24, Issue:6

    Topics: Animals; Beta Particles; Brachytherapy; Charcoal; Diphosphates; Female; Gelatin; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley

1997
Alterations in the Ha-ras-1 and the p53 pathway genes in the progression of N-methyl-N-nitrosourea-induced rat mammary tumors.
    Molecular carcinogenesis, 1997, Volume: 20, Issue:2

    Topics: Animals; Carcinogens; Disease Progression; Female; Gene Amplification; Genes, p53; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Inbred WF; Tumor Cells, Cultured

1997
Gene expression changes associated with chemically induced rat mammary carcinogenesis.
    Molecular carcinogenesis, 1997, Volume: 20, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Cloning, Molecular; Colonic Neoplasms; DNA, Neoplasm; Female; Gene Expression; Genetic Markers; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Homology, Amino Acid

1997
Telomerase activity in the normal and neoplastic rat mammary gland.
    Cancer research, 1997, Dec-15, Volume: 57, Issue:24

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Enzyme Activation; Epithelium; Female; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenotype; Pregnancy; Rats; Rats, Inbred Strains; Telomerase

1997
Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma.
    Cancer research, 1998, Feb-01, Volume: 58, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Cell Division; Drug Screening Assays, Antitumor; Drug Synergism; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoid X Receptors; Tamoxifen; Tetrahydronaphthalenes; Transcription Factors

1998
Fast repair of O6-ethylguanine, but not O6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Feb-17, Volume: 95, Issue:4

    Topics: Alkylation; Animals; Animals, Genetically Modified; DNA Adducts; DNA Repair; DNA, Neoplasm; Ethylnitrosourea; Female; Genes, ras; Guanine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; O(6)-Methylguanine-DNA Methyltransferase; Point Mutation; Rats; Transcription, Genetic

1998
Pathogenic characterization of 1-methyl-1-nitrosourea-induced mammary carcinomas in the rat.
    Carcinogenesis, 1998, Volume: 19, Issue:1

    Topics: Animals; Carcinogens; Codon; Female; Genes, ras; Genotype; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutagenesis; Point Mutation; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley

1998
Exercise during puberty and NMU induced mammary tumorigenesis in rats.
    Breast cancer research and treatment, 1998, Volume: 47, Issue:1

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Sexual Maturation

1998
Ovarian hormone dependence of pre-malignant and malignant mammary gland lesions induced in pre-pubertal rats by 1-methyl-1-nitrosourea.
    Carcinogenesis, 1998, Volume: 19, Issue:3

    Topics: Adenocarcinoma; Aging; Animals; Carcinogens; Cell Division; Female; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Ovary; Precancerous Conditions; Rats; Rats, Sprague-Dawley

1998
Promoter effect of medroxyprogesterone acetate (MPA) in N-methyl-N-nitrosourea (MNU) induced mammary tumors in BALB/c mice.
    Carcinogenesis, 1998, Volume: 19, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinogens; Cocarcinogenesis; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Methylnitrosourea; Mice; Mice, Inbred BALB C

1998
Expression of a vitamin D-regulated gene (VDUP-1) in untreated- and MNU-treated rat mammary tissue.
    Breast cancer research and treatment, 1998, Volume: 48, Issue:1

    Topics: Animals; Calcitriol; Female; Gene Expression Regulation; In Situ Hybridization; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Cells, Cultured

1998
Chemoprevention of N-nitroso-N-methylurea-induced rat mammary carcinogenesis by soy foods or biochanin A.
    Japanese journal of cancer research : Gann, 1998, Volume: 89, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Division; Diet; Female; Genistein; Glycine max; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1998
Synergistic effect of MNU and DMBA in mammary carcinogenesis and H-ras activation in female Sprague-Dawley rats.
    Cancer letters, 1997, Nov-25, Volume: 120, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Drug Synergism; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Point Mutation; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley

1997
Detection of differentially expressed genes in methylnitrosourea-induced rat mammary adenocarcinomas.
    Journal of cellular biochemistry. Supplement, 1997, Volume: 28-29

    Topics: Adenocarcinoma; Animals; Base Sequence; Carcinogens; DNA, Complementary; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Sequence Homology, Amino Acid

1997
Effect of early vs. late administration of 4-hydroxyphenylretinamide (4-HPR) on N-methyl-N-nitrosourea (MNU)-induced mammary tumorigenesis.
    Journal of cellular biochemistry. Supplement, 1997, Volume: 27

    Topics: Animals; Anticarcinogenic Agents; Base Sequence; Carcinogens; Codon; DNA Primers; Drug Administration Schedule; Feeding Behavior; Female; Fenretinide; Genes, ras; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Rats; Rats, Sprague-Dawley; S Phase; Weight Gain

1997
Insulin does not promote rat mammary carcinogenesis.
    Carcinogenesis, 1998, Volume: 19, Issue:4

    Topics: Animals; Blood Glucose; Body Weight; Carcinogens; Female; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1998
Radiochemical and radiopharmacological properties of pirocarbotrat and other labeled charcoal dispersions: comparative studies in rats with NMU-induced mammary tumors.
    Nuclear medicine and biology, 1998, Volume: 25, Issue:3

    Topics: Adenocarcinoma; Animals; Charcoal; Female; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Methylnitrosourea; Phosphates; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Tissue Distribution

1998
Microsatellite instability in an animal model of mammary carcinogenesis.
    International journal of oncology, 1998, Volume: 13, Issue:1

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; DNA Repair; Female; Genetic Markers; Mammary Neoplasms, Experimental; Methylnitrosourea; Microsatellite Repeats; Rats; Rats, Sprague-Dawley

1998
Dietary lignin, and insoluble fiber, enhance uterine cancer but did not influence mammary cancer induced by N-methyl-N-nitrosourea in rats.
    Nutrition and cancer, 1998, Volume: 31, Issue:1

    Topics: Adenocarcinoma; Animals; Body Weight; Brassica; Carcinoma, Squamous Cell; Dietary Fiber; Eating; Endometrial Neoplasms; Female; Lignin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Uterine Cervical Neoplasms

1998
Chemoprevention of N-nitroso-N-methylurea-induced rat mammary cancer by miso and tamoxifen, alone and in combination.
    Japanese journal of cancer research : Gann, 1998, Volume: 89, Issue:5

    Topics: Animals; Body Weight; Drug Therapy, Combination; Female; Glycine max; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen; Time Factors

1998
Inhibitory effects of nabumetone, a cyclooxygenase-2 inhibitor, and esculetin, a lipoxygenase inhibitor, on N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats.
    Japanese journal of cancer research : Gann, 1998, Volume: 89, Issue:5

    Topics: Animals; Butanones; Carcinogens; Cell Division; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Isoenzymes; Lipoxygenase Inhibitors; Mammary Neoplasms, Experimental; Methylnitrosourea; Nabumetone; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Time Factors; Umbelliferones

1998
Defective retrovirus insertion activates c-Ha-ras protooncogene in an MNU-induced rat mammary carcinoma.
    Biochemical and biophysical research communications, 1998, Jul-30, Volume: 248, Issue:3

    Topics: 3T3 Cells; Animals; Base Sequence; Cell Transformation, Neoplastic; Defective Viruses; Exons; Female; Genes, env; Genes, ras; Introns; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras); Rats; Recombinant Proteins; Repetitive Sequences, Nucleic Acid; Retroviridae; Transfection

1998
Suicide gene therapy of chemically induced mammary tumor in rat: efficacy and distant bystander effect.
    Cancer research, 1998, Aug-15, Volume: 58, Issue:16

    Topics: Animals; Antimetabolites; Carcinogens; Female; Ganciclovir; Genetic Therapy; Herpesvirus 1, Human; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Multiple Primary; Rats; Rats, Sprague-Dawley; Thymidine Kinase; Transfection

1998
Chemopreventive effects of the aromatase inhibitor vorozole (R 83842) in the methylnitrosourea-induced mammary cancer model.
    Carcinogenesis, 1998, Volume: 19, Issue:8

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Body Weight; Carcinogens; Drug Administration Schedule; Drug Screening Assays, Antitumor; Estradiol; Estrus; Female; Genes, ras; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Testosterone; Triazoles

1998
Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats.
    Carcinogenesis, 1998, Volume: 19, Issue:9

    Topics: Animals; Apoptosis; Blotting, Northern; Cell Division; Estrogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Pregnancy; Progesterone; Rats; Rats, Inbred WF; RNA, Messenger

1998
An experimental model of diabetes and cancer in rats.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anticarcinogenic Agents; Carcinogens; Cell Division; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Streptozocin; Tamoxifen

1998
Temporal sequence of mammary intraductal proliferations, ductal carcinomas in situ and adenocarcinomas induced by 1-methyl-1-nitrosourea in rats.
    Carcinogenesis, 1998, Volume: 19, Issue:12

    Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cell Division; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Time Factors

1998
Effect of reduced body weight gain on the evaluation of chemopreventive agents in the methylnitrosourea-induced mammary cancer model.
    Carcinogenesis, 1999, Volume: 20, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Diterpenes; Energy Intake; Female; Fenretinide; Food Deprivation; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Retinyl Esters; Vitamin A; Weight Gain

1999
Inhibition by dietary menhaden oil of cyclooxygenase-1 and -2 in N-nitrosomethylurea-induced rat mammary tumors.
    International journal of oncology, 1999, Volume: 14, Issue:3

    Topics: Animals; Corn Oil; Cyclooxygenase 1; Cyclooxygenase 2; Dietary Fats; Enzyme Inhibitors; Female; Fish Oils; Isoenzymes; Mammary Neoplasms, Experimental; Membrane Proteins; Methylnitrosourea; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344

1999
A comparative analysis of allelic imbalance events in chemically induced rat mammary, colon, and bladder tumors.
    Molecular carcinogenesis, 1999, Volume: 24, Issue:1

    Topics: Alleles; Animals; Azoxymethane; Butylhydroxybutylnitrosamine; Carcinogens; Chromosome Mapping; Codon; Colonic Neoplasms; Female; Genes, ras; Genetic Markers; Humans; Loss of Heterozygosity; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Microsatellite Repeats; Point Mutation; Rats; Rats, Inbred F344; Rats, Inbred WF; Urinary Bladder Neoplasms

1999
Hormonal prevention of breast cancer: mimicking the protective effect of pregnancy.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-02, Volume: 96, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cell Differentiation; Cell Division; Estradiol; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Perphenazine; Pregnancy; Progesterone; Rats; Rats, Inbred Lew

1999
Resistance to mammary tumorigenesis in Copenhagen rats is associated with the loss of preneoplastic lesions.
    Carcinogenesis, 1999, Volume: 20, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Drug Resistance; Female; Genes, ras; Genes, Tumor Suppressor; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Inbred WF

1999
Very low sensitivity of Wistar:Han female rats to chemocarcinogens in mammary carcinogenesis induction.
    Neoplasma, 1998, Volume: 45, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Rats, Wistar

1998
Protective effects of pregnancy and lactation against N-methyl-N-nitrosourea-induced mammary carcinomas in female Lewis rats.
    Carcinogenesis, 1999, Volume: 20, Issue:4

    Topics: Animals; Carcinogens; Cell Division; Estrogens; Female; Lactation; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Ovariectomy; Parity; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Rats, Inbred Lew; Receptors, Estrogen; Receptors, Progesterone

1999
Induction of mammary carcinomas by N-methyl-N-nitrosourea in ovariectomized rats treated with epidermal growth factor.
    Carcinogenesis, 1999, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Animals; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Cell Division; DNA Mutational Analysis; Epidermal Growth Factor; Estradiol; Estrogens; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Ovariectomy; Ovary; Polymerase Chain Reaction; Progesterone; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone

1999
Effect of energy restriction on the expression of cyclin D1 and p27 during premalignant and malignant stages of chemically induced mammary carcinogenesis.
    Molecular carcinogenesis, 1999, Volume: 24, Issue:4

    Topics: Adenocarcinoma; Animals; Carcinoma in Situ; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Cycle; Cell Cycle Proteins; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Energy Intake; Energy Metabolism; Female; Food Deprivation; Gene Expression Regulation, Neoplastic; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Microtubule-Associated Proteins; Neoplasm Proteins; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Tumor Suppressor Proteins

1999
Assessment of induced rat mammary tumour response to chemotherapy using the apparent diffusion coefficient of tissue water as determined by diffusion-weighted 1H-NMR spectroscopy in vivo.
    Magma (New York, N.Y.), 1999, Volume: 8, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinogens; Diffusion; Evaluation Studies as Topic; Female; Fluorouracil; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar; Water

1999
Polyunsaturated fatty acids and breast cancer.
    Lipids, 1999, Volume: 34 Suppl

    Topics: Animals; Antineoplastic Agents; Brassica; Breast Neoplasms; Cell Survival; Dietary Fats, Unsaturated; Fatty Acids, Monounsaturated; Female; Fish Oils; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Plant Oils; Rapeseed Oil; Tumor Cells, Cultured

1999
Dietary n-3 polyunsaturated fatty acids and oxidants increase rat mammary tumor sensitivity to epirubicin without change in cardiac toxicity.
    Lipids, 1999, Volume: 34 Suppl

    Topics: Animals; Dehydroascorbic Acid; Dietary Fats, Unsaturated; Epirubicin; Fatty Acids, Omega-3; Female; Lipid Peroxidation; Mammary Neoplasms, Experimental; Methylnitrosourea; Oxidants; Rats; Vitamin E; Vitamin K

1999
Fatty acid synthase gene expression in rat mammary carcinoma.
    Lipids, 1999, Volume: 34 Suppl

    Topics: Animals; Dietary Fats; Fatty Acid Synthases; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1999
4-(hydroxyphenyl)retinamide selectively inhibits the development and progression of ductal hyperplastic lesions and carcinoma in situ in mammary gland.
    Carcinogenesis, 1999, Volume: 20, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma in Situ; Disease Progression; Drug Screening Assays, Antitumor; Female; Fenretinide; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Sprague-Dawley

1999
Effect of energy restriction on tissue size regulation during chemically induced mammary carcinogenesis.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Adipose Tissue; Animals; Apoptosis; Carcinoma; Cell Division; Energy Metabolism; Female; Food Deprivation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

1999
Isolation of oncogenes from rat mammary tumors by a highly efficient retrovirus expression cloning system.
    Biochemical and biophysical research communications, 1999, Volume: 265, Issue:1

    Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Cloning, Molecular; Codon; Female; Genes, ras; Genetic Vectors; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Point Mutation; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley; Retroviridae; Transfection

1999
Selenium-induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake.
    Molecular carcinogenesis, 1999, Volume: 26, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Diet; Endothelial Growth Factors; Endothelium, Vascular; Female; Garlic; Gene Expression Regulation, Neoplastic; Humans; Lymphokines; Mammary Neoplasms, Experimental; Methylnitrosourea; Microcirculation; Neovascularization, Pathologic; Neovascularization, Physiologic; Phytotherapy; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Selenium; Sodium Selenite; Stromal Cells; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1999
Effect of dietary lycopene on N-methylnitrosourea-induced mammary tumorigenesis.
    Nutrition and cancer, 1999, Volume: 34, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Carotenoids; Diet; Female; Lycopene; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Risk Factors

1999
A new ligand for the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), GW7845, inhibits rat mammary carcinogenesis.
    Cancer research, 1999, Nov-15, Volume: 59, Issue:22

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Drug Screening Assays, Antitumor; Female; Ligands; Mammary Neoplasms, Experimental; Methylnitrosourea; Oxazoles; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Tamoxifen; Transcription Factors; Tyrosine

1999
Effect of the retinoid X receptor-selective ligand LGD1069 on mammary carcinoma after tamoxifen failure.
    Journal of the National Cancer Institute, 1999, Dec-15, Volume: 91, Issue:24

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Carcinogens; Disease Progression; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen; Tetrahydronaphthalenes; Treatment Failure; Treatment Outcome

1999
Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats.
    Nutrition and cancer, 1999, Volume: 35, Issue:1

    Topics: Adenocarcinoma; Animals; Butylene Glycols; Carcinogens; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flax; Glucosides; Lignans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytotherapy; Random Allocation; Rats; Rats, Sprague-Dawley

1999
S-allylcysteine, a garlic constituent, fails to inhibit N-methylnitrosourea-induced rat mammary tumorigenesis.
    Nutrition and cancer, 1999, Volume: 35, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinogens; Chromatography, High Pressure Liquid; Cysteine; Diet; Disease Models, Animal; Disease-Free Survival; Female; Garlic; Mammary Neoplasms, Experimental; Methylnitrosourea; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley

1999
Transgenic rats carrying human c-Ha-ras proto-oncogenes are highly susceptible to N-methyl-N-nitrosourea mammary carcinogenesis.
    Carcinogenesis, 2000, Volume: 21, Issue:2

    Topics: Animals; Animals, Genetically Modified; Carcinogens; Cocarcinogenesis; Codon; DNA Mutational Analysis; DNA, Neoplasm; Female; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Transfection

2000
Neoplastic transformation of mammary epithelial cells in rats is associated with decreased apoptotic cell death.
    Carcinogenesis, 2000, Volume: 21, Issue:2

    Topics: Animals; Apoptosis; Carcinogens; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cell Division; Cell Transformation, Neoplastic; Epithelial Cells; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Necrosis; Precancerous Conditions; Rats; Rats, Sprague-Dawley

2000
The effect of 2-methoxyoestrone-3-O-sulphamate on the growth of breast cancer cells and induced mammary tumours.
    International journal of cancer, 2000, Feb-15, Volume: 85, Issue:4

    Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Cycle; Cell Division; Estrone; Female; G2 Phase; Humans; Hydroxyestrones; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitosis; Rats; Receptors, Estrogen; Tumor Cells, Cultured

2000
Inhibition of N-methyl-N-nitrosourea- and 7,12-dimethylbenz[a] anthracene-induced rat mammary tumorigenesis by dietary cholesterol is independent of Ha-Ras mutations.
    Carcinogenesis, 2000, Volume: 21, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cholesterol, Dietary; Female; Genes, ras; Hydroxymethylglutaryl CoA Reductases; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Rats; Rats, Sprague-Dawley

2000
DNA repair: counteragent in mutagenesis and carcinogenesis-- accomplice in cancer therapy resistance.
    Mutation research, 2000, Volume: 462, Issue:2-3

    Topics: Adenocarcinoma; Alkylating Agents; Animals; Carcinogens; DNA; DNA Adducts; DNA Repair; Drug Resistance, Neoplasm; Ethylnitrosourea; Female; Genes, ras; Guanine; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutagens; Mutation; Rats

2000
Effect of intact and isoflavone-depleted soy protein on NMU-induced rat mammary tumorigenesis.
    Carcinogenesis, 2000, Volume: 21, Issue:5

    Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Female; Isoflavones; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred F344; Soybean Proteins

2000
Effect of an alpha-linolenic acid-rich diet on rat mammary tumor growth depends on the dietary oxidative status.
    Nutrition and cancer, 2000, Volume: 36, Issue:1

    Topics: alpha-Linolenic Acid; Animals; Antioxidants; Ascorbic Acid; Diet; Dietary Fats, Unsaturated; Female; Linseed Oil; Mammary Neoplasms, Experimental; Methylnitrosourea; Naphthoquinones; Oxidants; Rats; Rats, Sprague-Dawley; Vitamin E; Vitamin K 3

2000
Melatonin and 9-cis-retinoic acid in the chemoprevention of NMU-induced rat mammary carcinoma.
    Advances in experimental medicine and biology, 1999, Volume: 460

    Topics: Adenocarcinoma; Alitretinoin; Animals; Anticarcinogenic Agents; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tretinoin

1999
Effects of retinyl acetate and melatonin on N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats. A preliminary report.
    Folia biologica, 2000, Volume: 46, Issue:2

    Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Diterpenes; Drug Synergism; Female; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Retinyl Esters; Vitamin A

2000
Tn antigen is a pre-cancerous biomarker in breast tissue and serum in n-nitrosomethylurea-induced rat mammary carcinogenesis.
    International journal of cancer, 2000, Jun-15, Volume: 86, Issue:6

    Topics: Animals; Antigen-Antibody Complex; Antigens, Tumor-Associated, Carbohydrate; Biomarkers, Tumor; Female; Glycosylation; Immunohistochemistry; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Wistar

2000
In vitro and in vivo studies of methylseleninic acid: evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention.
    Cancer research, 2000, Jun-01, Volume: 60, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Comet Assay; Female; Glutathione Peroxidase; Liver; Lyases; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Thioredoxin-Disulfide Reductase; Tissue Distribution; Tumor Cells, Cultured

2000
Dietary butyrate inhibits NMU-induced mammary cancer in rats.
    Nutrition and cancer, 2000, Volume: 36, Issue:2

    Topics: Alkylating Agents; Animal Feed; Animals; Antineoplastic Agents; Butyrates; Dietary Fats; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Milk; Rats; Rats, Sprague-Dawley; Triglycerides

2000
In vivo inhibition of estrone sulfatase activity and growth of nitrosomethylurea-induced mammary tumors by 667 COUMATE.
    Cancer research, 2000, Jul-01, Volume: 60, Issue:13

    Topics: Animals; Antineoplastic Agents; Cell Division; Coumarins; Estrone; Female; Humans; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfatases; Sulfonamides; Sulfonic Acids; Time Factors; Uterus

2000
Histopathology of mammary tumours in female rats treated with 1-methyl-1-nitrosourea.
    Endocrine regulations, 2000, Volume: 34, Issue:2

    Topics: Adenocarcinoma; Animals; Carcinoma; Carcinoma in Situ; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2000
ras gene mutations are absent in NMU-induced mammary carcinomas from aging rats.
    Carcinogenesis, 2000, Volume: 21, Issue:10

    Topics: Aging; Animals; Carcinogens; Cocarcinogenesis; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Rats; Rats, Inbred WF; Transcriptional Activation

2000
Repeated administration of carcinogen in critical developmental periods increases susceptibility of female Wistar: han rats to mammary carcinogenesis induction.
    Neoplasma, 2000, Volume: 47, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Administration Schedule; Female; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar

2000
Cyclin D1 expression during rat mammary tumor development and its potential role in the resistance of the Copenhagen rat.
    Breast cancer research : BCR, 1999, Volume: 1, Issue:1

    Topics: Animals; Bromodeoxyuridine; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Inbred WF

1999
Prevention of N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats by 1alpha-hydroxyvitamin D(5).
    Journal of the National Cancer Institute, 2000, Nov-15, Volume: 92, Issue:22

    Topics: Animals; Anticarcinogenic Agents; Calcium; Carcinogens; Confidence Intervals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hydroxycholecalciferols; Incidence; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorus; Rats; Rats, Sprague-Dawley

2000
Induction of adipocyte-specific gene expression is correlated with mammary tumor regression by the retinoid X receptor-ligand LGD1069 (targretin).
    Cancer research, 2000, Nov-01, Volume: 60, Issue:21

    Topics: Adaptor Protein Complex 2; Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Adipocytes; Animals; Anticarcinogenic Agents; Bexarotene; Carcinogens; Cell Differentiation; Cell Division; Clone Cells; Complement Factor D; Female; Gene Expression; Growth Inhibitors; Ligands; Lipoprotein Lipase; Mammary Neoplasms, Experimental; Membrane Proteins; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Serine Endopeptidases; Tetrahydronaphthalenes; Transcription Factors; Tumor Cells, Cultured

2000
Tumorigenesis, metabolism, speciation, bioavailability, and tissue deposition of selenium in selenium-enriched ramps (Allium tricoccum).
    Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:11

    Topics: Allium; Animals; Anticarcinogenic Agents; Biological Availability; Cystathionine; Cysteine; Diet; Dipeptides; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Selenocysteine; Tissue Distribution

2000
Susceptibility of lean and obese Zucker rats to tumorigenesis induced by N-methyl-N-nitrosourea.
    Cancer letters, 2001, Jan-26, Volume: 162, Issue:2

    Topics: Alkylating Agents; Animals; Carcinogens; Cocarcinogenesis; DNA Methylation; Female; Hyperinsulinism; Insulin Resistance; Mammary Neoplasms, Experimental; Methylnitrosourea; Obesity; Rats; Rats, Zucker

2001
Classification of premalignant and malignant lesions developing in the rat mammary gland after injection of sexually immature rats with 1-methyl-1-nitrosourea.
    Journal of mammary gland biology and neoplasia, 2000, Volume: 5, Issue:2

    Topics: Adenocarcinoma; Animals; Carcinoma, Intraductal, Noninfiltrating; Female; Genes, ras; Hyperplasia; Lymphatic Metastasis; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Neoplasm Metastasis; Precancerous Conditions; Rats; Rats, Sprague-Dawley

2000
Effects of tamoxifen and melatonin on mammary gland cancer induced by N-methyl-N-nitrosourea and by 7,12-dimethylbenz(a)anthracene, respectively, in female Sprague-Dawley rats.
    Folia biologica, 2001, Volume: 47, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Estrogen Receptor Modulators; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen

2001
Detection of VIP receptors in MNU-induced breast cancer in rats: implications for breast cancer targeting.
    Breast cancer research and treatment, 2001, Volume: 65, Issue:1

    Topics: Alkylating Agents; Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Female; Fluorescein; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Vasoactive Intestinal Peptide

2001
[Study of the role of the feeding factor in the development of induced experimental mammary cancer in rats].
    Voprosy pitaniia, 2000, Volume: 69, Issue:5

    Topics: Animals; Cocarcinogenesis; Dietary Fats; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Soybean Proteins; Time Factors

2000
High susceptibility of transgenic rats carrying the human c-Ha-ras proto-oncogene to chemically-induced mammary carcinogenesis.
    Mutation research, 2001, Jun-02, Volume: 477, Issue:1-2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Rats

2001
Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid.
    Cancer letters, 2001, Jul-26, Volume: 168, Issue:2

    Topics: Adenocarcinoma; Alitretinoin; Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Carcinogens; Drug Synergism; Drug Therapy, Combination; Estradiol; Estrogen Receptor alpha; Female; Free Radical Scavengers; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Tretinoin; Uterus

2001
Parous rats regain high susceptibility to chemically induced mammary cancer after treatment with various mammotropic hormones.
    Carcinogenesis, 2001, Volume: 22, Issue:7

    Topics: Animals; Carcinogens; Cyclin D; Cyclins; DNA; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Rats; Rats, Sprague-Dawley; Thyroxine

2001
Short-term exposure to estrogen and progesterone induces partial protection against N-nitroso-N-methylurea-induced mammary tumorigenesis in Wistar--Furth rats.
    Cancer letters, 2001, Aug-10, Volume: 169, Issue:1

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Dose-Response Relationship, Drug; Drug Administration Schedule; Estrogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Rats; Rats, Inbred WF

2001
Modulatory effects of neonatal exposure to TCDD, or a mixture of PCBs, p,p'-DDT, and p-p'-DDE, on methylnitrosourea-induced mammary tumor development in the rat.
    Environmental health perspectives, 2001, Volume: 109, Issue:7

    Topics: Alkylating Agents; Animals; Breast; Cell Transformation, Neoplastic; DDT; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Insecticides; Mammary Neoplasms, Experimental; Methylnitrosourea; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

2001
VIP receptors as molecular targets of breast cancer: implications for targeted imaging and drug delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2001, Jul-06, Volume: 74, Issue:1-3

    Topics: Animals; Breast Neoplasms; Carcinogens; Drug Delivery Systems; Female; Fluorescent Dyes; Liposomes; Mammary Neoplasms, Experimental; Methylnitrosourea; Polyethylene Glycols; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, Vasoactive Intestinal Peptide

2001
Short-term exposure to pregnancy levels of estrogen prevents mammary carcinogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Sep-25, Volume: 98, Issue:20

    Topics: Alkylating Agents; Animals; Dose-Response Relationship, Drug; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Pregnancy; Rats; Rats, Inbred Lew; Silicone Elastomers; Time Factors

2001
MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice.
    Oncogene, 2001, Sep-20, Volume: 20, Issue:42

    Topics: Alkylating Agents; Animals; Carcinoma; DNA Methylation; DNA, Viral; Female; Genes, ras; Lymphoma, T-Cell; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylnitrosourea; Mice; Mice, Transgenic; Mutation; Promoter Regions, Genetic; Receptor, ErbB-2; Receptor, ErbB-3; RNA, Neoplasm; Terminal Repeat Sequences

2001
Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models.
    Cancer research, 2001, Oct-15, Volume: 61, Issue:20

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Ductal, Breast; Estrogens; Female; Humans; Luciferases; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Response Elements; Resveratrol; Selective Estrogen Receptor Modulators; Stilbenes; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins

2001
Preventive effects of raloxifene and melatonin in N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats.
    Neoplasma, 2001, Volume: 48, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Drinking; Eating; Female; Kinetics; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Organ Size; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Uterus

2001
LAS, a novel selective estrogen receptor modulator with chemopreventive and therapeutic activity in the N-nitroso-N-methylurea-induced rat mammary tumor model.
    Cancer research, 2001, Dec-15, Volume: 61, Issue:24

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Carcinogens; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Pyrrolidines; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Weight Gain

2001
Growth and characterization of N-methyl-N-nitrosourea-induced mammary tumors in intact and ovariectomized rats.
    Carcinogenesis, 2001, Volume: 22, Issue:12

    Topics: Animals; Aromatase; Cell Differentiation; Cyclin D1; ErbB Receptors; Estradiol; Estrogen Receptor alpha; Female; Growth Hormone; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitogen-Activated Protein Kinases; Ovariectomy; Prolactin; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, Progesterone; Ribonucleases; RNA, Messenger; Somatomedins

2001
Altered gene expression profile in chemically induced rat mammary adenocarcinomas and its modulation by an aromatase inhibitor.
    Oncogene, 2001, Nov-22, Volume: 20, Issue:53

    Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Aromatase; Aromatase Inhibitors; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Sequence Homology, Amino Acid; Triazoles; Up-Regulation

2001
Effect of dietary zinc intake on N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats.
    Biological trace element research, 2001, Volume: 83, Issue:2

    Topics: Animals; Carcinogens; Diet; Eating; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Weight Gain; Zinc

2001
Semi-automated method of quantifying vasculature of 1-methyl-1-nitrosourea-induced rat mammary carcinomas using immunohistochemical detection.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2002, Volume: 50, Issue:2

    Topics: Animals; Carcinogens; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley

2002
Mammary carcinomas induced in human c-Ha-ras proto-oncogene transgenic rats are estrogen-independent, but responsive to d-limonene treatment.
    Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:1

    Topics: Adenocarcinoma; Animals; Animals, Genetically Modified; Antineoplastic Agents, Phytogenic; Carcinogens; Cyclohexenes; Estrogens; Female; Genes, ras; Humans; Limonene; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Ovariectomy; Protein Prenylation; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Terpenes

2002
Effect of the aromatase inhibitor vorozole on estrogen and progesterone receptor content of rat mammary carcinomas induced by 1-methyl-1-nitrosourea.
    Breast cancer research and treatment, 2001, Volume: 70, Issue:3

    Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Diet; Drug Administration Schedule; Epithelial Cells; Female; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Triazoles

2001
Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer.
    Molecular carcinogenesis, 2002, Volume: 33, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Southern; Breast Neoplasms; Carcinogens; Carcinoma in Situ; Carcinoma, Ductal, Breast; Chromosome Aberrations; DNA, Neoplasm; Estrogens; Female; Genes, myc; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Invasiveness; Ploidies; Rats; Rats, Inbred ACI; Rats, Sprague-Dawley; Testosterone

2002
Synergistic tumor promoter effects of estrone and progesterone in methylnitrosourea-induced rat mammary cancer.
    Cancer letters, 2002, May-28, Volume: 179, Issue:2

    Topics: Alkylating Agents; Animals; Body Weight; Drug Synergism; Estrone; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Ovariectomy; Pituitary Gland; Progesterone; Rats; Rats, Sprague-Dawley; Time Factors; Uterus

2002
Decreased susceptibility to NMU-induced mammary carcinogenesis in transgenic rats carrying multiple copies of a rat ras gene driven by the rat Harvey ras promoter.
    Oncogene, 2002, Apr-25, Volume: 21, Issue:18

    Topics: Animals; Animals, Genetically Modified; Carcinogens; Disease Susceptibility; Female; Gene Dosage; Genes, ras; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutagenesis; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley

2002
Tumor prevention by 9-cis-retinoic acid in the N-nitroso-N-methylurea model of mammary carcinogenesis is potentiated by the pineal hormone melatonin.
    Breast cancer research and treatment, 2002, Volume: 72, Issue:1

    Topics: Administration, Oral; Alitretinoin; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tretinoin

2002
Vascular density profile of rat mammary carcinomas induced by 1-methyl-1-nitrosourea: implications for the investigation of angiogenesis.
    Carcinogenesis, 2002, Volume: 23, Issue:5

    Topics: Animals; Carcinogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley

2002
In vivo quantitation of tumour vascularisation assessed by Doppler sonography in rat mammary tumours.
    Ultrasound in medicine & biology, 2002, Volume: 28, Issue:4

    Topics: Animals; Antineoplastic Agents; Epirubicin; Feasibility Studies; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Animal; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Ultrasonography, Doppler

2002
The growth hormone-deficient Spontaneous Dwarf rat is resistant to chemically induced mammary carcinogenesis.
    Carcinogenesis, 2002, Volume: 23, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Cell Division; Crosses, Genetic; Disease Models, Animal; Dwarfism; Female; Growth Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley

2002
Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis.
    Breast cancer research and treatment, 2002, Volume: 73, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoviridae; Animals; Antiviral Agents; beta-Galactosidase; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Ganciclovir; Gene Expression Regulation, Developmental; Immunoenzyme Techniques; Incidence; Injections, Intralesional; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred WF; Thymidine Kinase

2002
Thymosin alpha1 inhibits mammary carcinogenesis in Fisher rats.
    Peptides, 2002, Volume: 23, Issue:5

    Topics: Animals; Blood Chemical Analysis; Cell Transformation, Neoplastic; Female; Leukocyte Count; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred F344; Thymalfasin; Thymosin

2002
Cyclooxygenase-2 inhibitor celecoxib inhibits promotion of mammary tumorigenesis in rats fed a high fat diet rich in n-6 polyunsaturated fatty acids.
    Cancer letters, 2002, Oct-08, Volume: 184, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dietary Fats; Dietary Fats, Unsaturated; Dose-Response Relationship, Drug; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Isoenzymes; Mammary Neoplasms, Experimental; Methylnitrosourea; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides

2002
Analysis of mammary tumors for cytochemical evidence of endogenous mammary peroxidase.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1979, Volume: 31, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Peroxidases; Pregnancy; Rats

1979
Neoplastic transformation of rat mammary cells exposed to 7,12-dimethylbenz[alpha]anthracene or N-nitrosomethylurea in cell culture.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats

1978
Acquisition of angiogenic capacity and neoplastic transformation in the rat mammary gland.
    Cancer research, 1978, Volume: 38, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred BN; Rats, Inbred F344

1978
Fat droplet formation in rat lactating mammary gland and mammary carcinomas viewed by freeze-fracture.
    Laboratory investigation; a journal of technical methods and pathology, 1979, Volume: 40, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Endoplasmic Reticulum; Female; Freeze Fracturing; Golgi Apparatus; Intracellular Membranes; Lactation; Lipids; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Membrane Lipids; Methylnitrosourea; Pregnancy; Rats

1979
Hormonal regulation in two rat mammary cancer cell lines: glucocorticoid and androgen receptors.
    Molecular and cellular endocrinology, 1979, Volume: 13, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Line; Cytosol; Dexamethasone; Dihydrotestosterone; Estradiol; Estrenes; Female; Hydrocortisone; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Rats; Receptors, Androgen; Receptors, Glucocorticoid; Receptors, Steroid; Testosterone Congeners

1979
N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat.
    Cancer research, 1979, Volume: 39, Issue:4

    Topics: Animals; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Rats; Trachea; Tretinoin; Vitamin A; Vitamin A Deficiency

1979
Effects of iodine deficiency and high-fat diet on N-nitrosomethylurea-induced mammary cancers in rats.
    Cancer research, 1979, Volume: 39, Issue:3

    Topics: Animals; Castration; Dietary Fats; Female; Growth Hormone; In Vitro Techniques; Iodine; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Ovary; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Thyrotropin

1979
O6-methylguanine accumulates in DNA of mammary glands after administration of N-methyl-N-nitrosourea to rats.
    Cancer letters, 1979, Volume: 6, Issue:4-5

    Topics: Animals; Brain; DNA; DNA Repair; Female; Guanine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylation; Methylnitrosourea; Nitrosourea Compounds; Rats; Urinary Bladder

1979
Effect of the duration of retinyl acetate feeding on inhibition of 1-methyl-1-nitrosourea-induced mammary carcinogenesis in the rat.
    Cancer research, 1979, Volume: 39, Issue:10

    Topics: Adenocarcinoma; Animals; Diterpenes; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Retinyl Esters; Time Factors; Vitamin A

1979
Influence of dietary fat on the induction of mammary tumors by N-nitrosomethylurea: associated hormone changes and differences between Sprague-Dawley and F344 rats.
    Journal of the National Cancer Institute, 1977, Volume: 59, Issue:4

    Topics: Adenocarcinoma; Animals; Body Weight; Dietary Fats; Estrogens; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Pregnancy; Prolactin; Rats; Rats, Inbred F344; Species Specificity

1977
[Effect of N-nitroso-N'-methylurea on the cellular kinetics in tumors].
    Voprosy onkologii, 1977, Volume: 23, Issue:2

    Topics: Animals; Cell Count; DNA, Neoplasm; Female; Kinetics; Leukemia L1210; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mitosis; Nitrosourea Compounds; Thymidine; Time Factors; Tritium

1977
Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea.
    Nature, 1977, Jun-16, Volume: 267, Issue:5612

    Topics: Animals; Diterpenes; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Retinyl Esters; Time Factors; Vitamin A

1977
Effects of altered thyroid states on mammary tumor growth and pituitary gland function in rats.
    Journal of the National Cancer Institute, 1977, Volume: 59, Issue:3

    Topics: Animals; DNA, Neoplasm; Female; Growth Hormone; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Pituitary Gland; Prolactin; Rats; Rats, Inbred BUF; Thyroid Gland; Thyrotropin; Thyroxine; Transplantation, Isogeneic; Triiodothyronine

1977
The effect of isoprenaline on induction of tumours by methyl nitrosourea in the salivary and mammary glands of female wistar rats.
    British journal of cancer, 1976, Volume: 34, Issue:4

    Topics: Animals; DNA; Female; Isoproterenol; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Parotid Neoplasms; Rats; Salivary Gland Neoplasms; Salivary Glands; Stimulation, Chemical; Time Factors

1976
Leukemias and vaginal tumors induced in female Donryu rats by continuous administration of 1-butyl-3,3-dimethyl-1-nitrosourea in the drinking water.
    Journal of the National Cancer Institute, 1976, Volume: 56, Issue:6

    Topics: Animals; Ear Neoplasms; Female; Leukemia, Experimental; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Vaginal Neoplasms

1976
Tumours in the mammary gland induced in Lewis rats by intravenous methylnitrosurea.
    British journal of cancer, 1975, Volume: 31, Issue:3

    Topics: Adenocarcinoma, Papillary; Animals; Brain Neoplasms; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats

1975
[Growth kinetics of transplantable mammary gland tumors in mice].
    Voprosy onkologii, 1975, Volume: 21, Issue:10

    Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Ethylnitrosourea; Kinetics; Male; Mammary Neoplasms, Experimental; Mathematics; Methylnitrosourea; Mice; Mice, Inbred A; Mice, Inbred C3H; Neoplasm Transplantation; Nitrosourea Compounds; Time Factors

1975
Induction of neurogenic and lymphoid neoplasms by the feeding of threshold levels of methyl- and ethylnitrousourea precursors to adult rats.
    Food and cosmetics toxicology, 1975, Volume: 13, Issue:6

    Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Lymphoma; Mammary Neoplasms, Experimental; Methylnitrosourea; Methylurea Compounds; Neoplasms, Experimental; Nitrites; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pituitary Neoplasms; Rats; Urea

1975
Ductal carcinoma in situ in rat mammary gland.
    The Journal of surgical research, 1992, Volume: 52, Issue:3

    Topics: Animals; Carcinoma in Situ; Carcinoma, Intraductal, Noninfiltrating; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Receptors, Estrogen

1992
Separation, purification and N-terminal sequence analysis of a novel leupeptin-sensitive serine endopeptidase present in chemically induced rat mammary tumour.
    The Biochemical journal, 1992, Apr-01, Volume: 283 ( Pt 1)

    Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Benzoylarginine Nitroanilide; Chromatography, Gel; Electrophoresis; Enzyme Activation; Enzyme Stability; Female; Hydrogen-Ion Concentration; Hydrolysis; Isoelectric Point; Leupeptins; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Sequence Homology, Nucleic Acid; Serine Endopeptidases; Substrate Specificity; Tissue Extracts

1992
Down-regulation of tenascin expression by antiprogestins during terminal differentiation of rat mammary tumors.
    Cancer research, 1992, Sep-01, Volume: 52, Issue:17

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Extracellular Matrix Proteins; Female; Gonanes; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Progesterone; Rats; Tamoxifen; Tenascin; Uterus

1992
Incidence of c-Ki-ras activation in N-methyl-N-nitrosourea-induced mammary carcinomas in pituitary-isografted mice.
    Cancer research, 1992, Oct-15, Volume: 52, Issue:20

    Topics: Animals; Base Sequence; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasm Transplantation; Pituitary Gland, Anterior; Subrenal Capsule Assay; Transplantation, Isogeneic

1992
Effect of carcinogen dose and age at administration on induction of mammary carcinogenesis by 1-methyl-1-nitrosourea.
    Carcinogenesis, 1992, Volume: 13, Issue:9

    Topics: Adenocarcinoma; Age Factors; Animals; Carcinogens; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Rats; Rats, Sprague-Dawley

1992
Investigations of droloxifene and other hormone manipulations on N-nitrosomethylurea-induced rat mammary tumours. 1. Influence on tumour growth.
    Journal of cancer research and clinical oncology, 1992, Volume: 119, Issue:2

    Topics: Animals; Antineoplastic Agents; Body Weight; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Sprague-Dawley; Tamoxifen

1992
Investigations of droloxifene and other hormonal manipulations on N-nitrosomethylurea-induced rat mammary tumours. 2. Influence on oestrogen receptor.
    Journal of cancer research and clinical oncology, 1992, Volume: 119, Issue:2

    Topics: Aminoglutethimide; Animals; Antineoplastic Agents; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Receptors, Estrogen; Tamoxifen

1992
Effects of folate deficiency and supplementation on methylnitrosourea-induced rat mammary tumors.
    Journal of the National Cancer Institute, 1992, Nov-18, Volume: 84, Issue:22

    Topics: Animals; Folic Acid; Folic Acid Deficiency; Hematocrit; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred F344

1992
Antitumor activity of alkylphosphocholines and analogues in methylnitrosourea-induced rat mammary carcinomas.
    Progress in experimental tumor research, 1992, Volume: 34

    Topics: Animals; Antineoplastic Agents; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorylcholine; Rats; Rats, Inbred Strains

1992
ras oncogene activation in mammary carcinomas induced by N-methyl-N-nitrosourea in Copenhagen rats.
    Molecular carcinogenesis, 1992, Volume: 6, Issue:4

    Topics: Adenocarcinoma; Animals; Base Sequence; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Mutagenesis; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rats; Rats, Inbred BUF; Rats, Inbred Strains

1992
Mammary tumor induction by N-methyl-N-nitrosourea in genetically resistant Copenhagen rats.
    Cancer research, 1992, Sep-15, Volume: 52, Issue:18

    Topics: Adenocarcinoma; Age Factors; Animals; Immunity, Innate; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1992
Effect of tamoxifen on preneoplastic cell proliferation in N-nitroso-N-methylurea-induced mammary carcinogenesis.
    Cancer research, 1992, Mar-15, Volume: 52, Issue:6

    Topics: Animals; Cell Division; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Inbred Strains; Tamoxifen

1992
Mammary carcinogenesis induced by N-methyl-N-nitrosourea (MNU) and medroxyprogesterone acetate (MPA) in BALB/c mice.
    Breast cancer research and treatment, 1992, Volume: 20, Issue:2

    Topics: Adenocarcinoma; Animals; Disease Models, Animal; Drug Synergism; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Methylnitrosourea; Mice; Mice, Inbred BALB C; Receptors, Estrogen; Receptors, Progesterone

1992
Histologic evaluation of rat mammary tumor necrosis by interstitial Nd:YAG laser hyperthermia.
    Lasers in surgery and medicine, 1992, Volume: 12, Issue:2

    Topics: Adenocarcinoma; Animals; Dose-Response Relationship, Radiation; Evaluation Studies as Topic; Female; Hyperthermia, Induced; Laser Therapy; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Necrosis; Rats; Rats, Inbred Strains

1992
Formation and repair of O6-methylguanine and methylation of the Ha-ras proto-oncogene by N-methyl-N-nitrosourea are not associated with mammary tumor resistance in the Copenhagen rat.
    Carcinogenesis, 1992, Volume: 13, Issue:5

    Topics: Animals; Blotting, Northern; Blotting, Southern; DNA Repair; DNA, Neoplasm; Drug Resistance; Female; Genes, ras; Guanine; Mammary Neoplasms, Experimental; Methylation; Methylnitrosourea; Rats

1992
Alkylphosphocholines: influence of structural variation on biodistribution at antineoplastically active concentrations.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphatidylcholines; Phosphorylcholine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tissue Distribution

1992
Influence of reducing luxury calories in the treatment of experimental mammary carcinoma.
    British journal of cancer, 1992, Volume: 65, Issue:6

    Topics: Animals; Body Weight; Dietary Fats; Energy Intake; Estradiol; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Recurrence; Testosterone

1992
Limonene-induced regression of mammary carcinomas.
    Cancer research, 1992, Jul-15, Volume: 52, Issue:14

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclohexenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Limonene; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Terpenes

1992
Effects of dietary fiber on N-nitrosomethylurea-induced mammary tumors and on plasma estrogen levels in rats.
    Journal of the National Cancer Institute, 1991, Sep-18, Volume: 83, Issue:18

    Topics: Animals; Dietary Fiber; Estrogens; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred F344

1991
Influence of wheat bran on NMU-induced mammary tumor development, plasma estrogen levels and estrogen excretion in female rats.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:2

    Topics: Animals; Dietary Fiber; Estrogens; Feces; Female; Glucuronidase; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred F344; Triticum

1991
Modulation of N-nitrosomethylurea-induced mammary tumor promotion by dietary fiber and fat.
    Journal of the National Cancer Institute, 1991, Apr-03, Volume: 83, Issue:7

    Topics: Animals; Body Weight; Charcoal; Dextrans; Dietary Fats; Dietary Fiber; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogens; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Radioimmunoassay; Rats; Rats, Inbred F344; Tritium

1991
Oestrone sulphatase activity in mammary tumours and the liver of N-nitrosomethylurea treated rats.
    British journal of cancer, 1992, Volume: 65, Issue:1

    Topics: Animals; Cytosol; Estradiol; Female; Hydrogen-Ion Concentration; Kinetics; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Inbred Strains; Sulfatases

1992
Ha-ras oncogene activation in mammary glands of N-methyl-N-nitrosourea-treated rats genetically resistant to mammary adenocarcinogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Feb-01, Volume: 89, Issue:3

    Topics: Animals; Base Sequence; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Proto-Oncogene Proteins p21(ras); Rats

1992
Pineal melatonin inhibition of tumor promotion in the N-nitroso-N-methylurea model of mammary carcinogenesis: potential involvement of antiestrogenic mechanisms in vivo.
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:6

    Topics: Animals; Disease Models, Animal; Estradiol; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Mice; Neoplasm Recurrence, Local; Ovariectomy; Pineal Gland; Prolactin; Radioimmunoassay; Receptors, Estrogen; Tamoxifen

1991
Low-frequency electromagnetic radiation enhances the induction of rat mammary tumors by nitrosomethyl urea.
    Cancer letters, 1991, Dec-09, Volume: 61, Issue:1

    Topics: Adenocarcinoma; Adenofibroma; Animals; Electromagnetic Fields; Female; Incidence; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Radiation-Induced; Rats

1991
Dietary soybean isolate and methionine supplementation affect mammary tumor progression in rats.
    The Journal of nutrition, 1991, Volume: 121, Issue:10

    Topics: Animals; Body Weight; Carcinogens; Caseins; Diet; Female; Glycine max; Injections, Intravenous; Mammary Neoplasms, Experimental; Methionine; Methylnitrosourea; Rats; Rats, Inbred Strains

1991
Inhibition of rat mammary gland chemical carcinogenesis by dietary dehydroepiandrosterone or a fluorinated analogue of dehydroepiandrosterone.
    Cancer research, 1991, Jan-15, Volume: 51, Issue:2

    Topics: Androstenes; Animals; Antineoplastic Agents; Dehydroepiandrosterone; Diet; Drug Therapy, Combination; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tretinoin

1991
[The effect of low-frequency electromagnetic fields on the development of experimental mammary tumors].
    Voprosy onkologii, 1991, Volume: 37, Issue:9-10

    Topics: Adenocarcinoma; Adenofibroma; Animals; Chi-Square Distribution; Electromagnetic Fields; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Time Factors

1991
A comparison of tocopherol and tocotrienol for the chemoprevention of chemically induced rat mammary tumors.
    The American journal of clinical nutrition, 1991, Volume: 53, Issue:4 Suppl

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Vitamin E

1991
Treatment of chemically induced autochthonous rat mammary and colorectal carcinomas with interleukin-2.
    Cancer immunology, immunotherapy : CII, 1991, Volume: 33, Issue:5

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Colorectal Neoplasms; Cyclophosphamide; Dimethylnitrosamine; Female; Interleukin-2; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Rats; Rats, Inbred Strains

1991
Mutational activation of c-Ha-ras genes in intraductal proliferation induced by N-nitroso-N-methylurea in rat mammary glands.
    International journal of cancer, 1991, Aug-19, Volume: 49, Issue:1

    Topics: Animals; Base Sequence; Cell Division; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Oligonucleotides; Polymerase Chain Reaction; Rats; Rats, Inbred F344

1991
4-Hydroxyandrostenedione in the prophylaxis of N-methyl-N-nitrosourea induced mammary tumourigenesis.
    British journal of cancer, 1991, Volume: 64, Issue:2

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Random Allocation; Rats; Rats, Inbred Strains; Time Factors

1991
A mammary cancer suppressor gene and its site of action in the rat.
    Cancer research, 1991, Mar-15, Volume: 51, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Female; Genes, Tumor Suppressor; Homozygote; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Rats; Rats, Inbred Strains

1991
Effect of canthaxanthin on chemically induced mammary carcinogenesis.
    Oncology, 1991, Volume: 48, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Canthaxanthin; Carotenoids; Diterpenes; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Retinyl Esters; Vitamin A

1991
Influence of caffeine on development of benign and carcinomatous mammary gland tumors in female rats treated with the carcinogens 7,12-dimethylbenz(a)anthracene and N-methyl-N-nitrosourea.
    Cancer research, 1991, Jul-01, Volume: 51, Issue:13

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caffeine; Carcinogens; Drug Synergism; Feces; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1991
The role of Ha-ras oncogenes in growth factor independence in rat mammary carcinoma cells.
    Molecular carcinogenesis, 1991, Volume: 4, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Cell Division; Codon; DNA, Neoplasm; Exons; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymerase Chain Reaction; Rats; Transfection

1991
Biochemical characteristics of cytosolic and particulate forms of protein tyrosine kinases from N-methyl-N-nitrosourea (MNU)-induced rat mammary carcinoma.
    Molecular and cellular biochemistry, 1991, Jul-24, Volume: 106, Issue:1

    Topics: Animals; Cytosol; Detergents; Female; Kinetics; Mammary Neoplasms, Experimental; Metals; Methylnitrosourea; Octoxynol; Polyethylene Glycols; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Sodium Chloride; Subcellular Fractions; Substrate Specificity

1991
In vitro investigations on the antineoplastic effect of hexadecylphosphocholine.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Breast Neoplasms; Colony-Forming Units Assay; Humans; KB Cells; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Nitrosourea Compounds; Phospholipid Ethers; Phosphorylcholine; Rats; Rats, Inbred Strains; Tumor Cells, Cultured

1991
Pyrrolidino-4-iodotamoxifen and 4-iodotamoxifen, new analogues of the antiestrogen tamoxifen for the treatment of breast cancer.
    Cancer research, 1991, Nov-01, Volume: 51, Issue:21

    Topics: Animals; Breast Neoplasms; Cell Division; Cell Line; Drug Screening Assays, Antitumor; Estradiol Congeners; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen

1991
Effect of deficiencies of selenium and vitamin E alone or in combination on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea.
    Carcinogenesis, 1991, Volume: 12, Issue:11

    Topics: Analysis of Variance; Animals; Antioxidants; Body Weight; Diet; Dose-Response Relationship, Drug; Drug Synergism; Female; Glutathione Peroxidase; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Regression Analysis; Selenium; Vitamin E Deficiency

1991
Effect of dietary iron deficiency or excess on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea.
    Carcinogenesis, 1991, Volume: 12, Issue:1

    Topics: Animals; Body Weight; Female; Iron; Iron Deficiencies; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1991
Estrous cycle dependence of nitrosomethylurea (NMU)-induced preneoplastic lesions in rat mammary gland.
    Cancer letters, 1991, Volume: 56, Issue:1

    Topics: Analysis of Variance; Animals; Estrus; Female; Hyperplasia; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors

1991
Quantitating the frequency of initiation and cH-ras mutation in in situ N-methyl-N-nitrosourea-exposed rat mammary gland.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1991, Volume: 2, Issue:1

    Topics: Animals; Base Sequence; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Mutation; Rats

1991
Effect of dietary calorie and fat restriction on mammary tumor growth and hepatic as well as tumor glutathione in rats.
    Cancer letters, 1991, May-01, Volume: 57, Issue:2

    Topics: Animals; Body Weight; Dietary Fats; Energy Intake; Female; Glutathione; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Protein Biosynthesis; Rats; Rats, Inbred Strains

1991
Generation of monoclonal antibodies specific for ras p21 Glu-12 oncoproteins: detection in carcinogen-induced mammary carcinomas.
    Hybridoma, 1991, Volume: 10, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antibody Specificity; Cell Line, Transformed; Female; Hybridomas; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Oncogene Protein p21(ras); Rats

1991
Dietary N-3 fatty acids do not affect induction of Ha-ras mutations in mammary glands of NMU-treated rats.
    Molecular carcinogenesis, 1991, Volume: 4, Issue:2

    Topics: Animals; Base Sequence; Codon; Dietary Fats; DNA; DNA, Neoplasm; Fatty Acids; Fatty Acids, Unsaturated; Female; Gene Amplification; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Mutagenesis; Oligonucleotide Probes; Rats; Rats, Inbred F344

1991
Dose-responsive induction of mammary gland carcinomas by the intraperitoneal injection of 1-methyl-1-nitrosourea.
    Cancer research, 1991, Jul-01, Volume: 51, Issue:13

    Topics: Animals; Carcinoma; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Survival Analysis; Time Factors

1991
Monitoring therapeutic response to tamoxifen in NMU-induced rat mammary tumours by 31P MRS.
    British journal of cancer, 1991, Volume: 63, Issue:6

    Topics: Animals; Female; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Methylnitrosourea; Nucleotides; Phosphates; Phosphorus; Rats; Rats, Inbred Strains; Tamoxifen

1991
Genetic instability and the acquisition of metastatic ability by rat mammary cancer cells following v-H-ras oncogene transfection.
    Cancer research, 1990, Oct-01, Volume: 50, Issue:19

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Chromosome Aberrations; Chromosome Disorders; DNA, Neoplasm; Female; Genes, ras; Karyotyping; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Ploidies; Rats; Rats, Inbred Strains; Transfection

1990
Molecular cloning of rat Krev-1 cDNA and analysis of the mRNA levels in normal and NMU-induced mammary carcinomas.
    Carcinogenesis, 1990, Volume: 11, Issue:7

    Topics: Animals; Base Sequence; Brain Chemistry; Gene Library; GTP-Binding Proteins; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; rap GTP-Binding Proteins; Rats; Rats, Inbred Strains; Rats, Inbred WF; RNA, Messenger; RNA, Neoplasm; Specific Pathogen-Free Organisms

1990
Transforming c-Ki-ras mutation is a preneoplastic event in mouse mammary carcinogenesis induced in vitro by N-methyl-N-nitrosourea.
    Molecular and cellular biology, 1990, Volume: 10, Issue:4

    Topics: Animals; Base Sequence; Blotting, Southern; Cell Transformation, Neoplastic; Cells, Cultured; DNA Probes; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; Precancerous Conditions; Restriction Mapping

1990
Activation of ras oncogenes preceding the onset of neoplasia.
    Science (New York, N.Y.), 1990, Jun-01, Volume: 248, Issue:4959

    Topics: Adenofibroma; Animals; Animals, Newborn; Base Sequence; Carcinoma; Cell Transformation, Neoplastic; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred Strains; Sexual Maturation; Time Factors

1990
Reduction in the frequency of activated ras oncogenes in rat mammary carcinomas with increasing N-methyl-N-nitrosourea doses or increasing prolactin levels.
    Cancer research, 1990, Jul-15, Volume: 50, Issue:14

    Topics: Adrenalectomy; Animals; Base Sequence; Desoxycorticosterone; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Prolactin; Rats; Rats, Inbred WF

1990
Role of insulin-like growth factor-related peptides in the estradiol-, prolactin-, and progesterone-stimulated growth of N-nitrosomethylurea-induced rat mammary tumors in soft agar.
    Cancer research, 1990, Nov-15, Volume: 50, Issue:22

    Topics: Animals; Cell Division; Estradiol; Female; Immunologic Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Prolactin; Rats; Rats, Inbred Strains; Somatomedins

1990
Specific inhibitory effect of dietary eicosapentaenoic acid on N-nitroso-N-methylurea-induced mammary carcinogenesis in female Sprague-Dawley rats.
    Carcinogenesis, 1990, Volume: 11, Issue:11

    Topics: Animals; Dietary Fats; Eicosapentaenoic Acid; Fatty Acids; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1990
Differential relationship of vitamin A and E levels in methylnitrosourea-induced Sprague-Dawley rats following prolonged feeding of fatty diets enriched with the vitamins.
    Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:5

    Topics: Animals; Dietary Fats; Female; Lipids; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Vitamin A; Vitamin E

1990
Neoplastic transformation and DNA damage of mouse mammary epithelial cells by N-methyl-N'-nitrosourea in organ culture.
    Cancer letters, 1990, Nov-19, Volume: 55, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; DNA Damage; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Organ Culture Techniques

1990
Androgen-linked alkylating agents: biological activity in methylnitrosourea-induced rat mammary carcinoma.
    Journal of cancer research and clinical oncology, 1990, Volume: 116, Issue:6

    Topics: Alkylating Agents; Androgens; Animals; Antineoplastic Agents; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Progesterone; Structure-Activity Relationship

1990
A computer program for the statistical analysis of cancer inhibition/promotion experiments.
    Computer methods and programs in biomedicine, 1990, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinogens; Computer Simulation; Diterpenes; Mammary Neoplasms, Experimental; Mathematical Computing; Methylnitrosourea; Models, Biological; Neoplasms, Experimental; Programming Languages; Rats; Retinyl Esters; Software; Software Design; Vitamin A

1990
[Modifying effects of pregnancy and lactation on the structure of N-methyl-N-nitrosourea-induced tumors of the mammary glands in rats].
    Voprosy onkologii, 1990, Volume: 36, Issue:12

    Topics: Adenocarcinoma; Adenofibroma; Adenoma; Animals; Female; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Pregnancy, Animal; Rats

1990
31P-NMR spectroscopy and histological studies of the response of rat mammary tumours to endocrine therapy.
    British journal of cancer, 1990, Volume: 61, Issue:2

    Topics: Adenocarcinoma; Animals; Basement Membrane; Female; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitotic Index; Ovariectomy; Rats; Rats, Inbred Strains; Time Factors

1990
DNA methyl-adduct dosimetry and O6-alkylguanine-DNA alkyl transferase activity determinations in rat mammary carcinogenesis by procarbazine and N-methylnitrosourea.
    Carcinogenesis, 1990, Volume: 11, Issue:3

    Topics: Animals; DNA; Female; Mammary Neoplasms, Experimental; Methylation; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Procarbazine; Rats; Rats, Inbred Strains

1990
Role of transforming growth factor-alpha-related peptides in the autocrine/paracrine control of experimental breast cancer growth in vitro by estradiol, prolactin, and progesterone.
    Breast cancer research and treatment, 1990, Volume: 15, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Breast Neoplasms; ErbB Receptors; Estradiol; Female; Humans; In Vitro Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Prolactin; Rats; Rats, Inbred Strains; Transforming Growth Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay

1990
Effects of cyclosporine A on Ia antigen expression in N-nitroso-N-methylurea-induced rat mammary tumors.
    Cancer research, 1990, Jun-01, Volume: 50, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Binding, Competitive; Cyclosporins; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Rats

1990
Effects of different levels of dietary fat on methyl-nitrosourea-induced mammary carcinogenesis in correlation with parameters of fat metabolism in female Sprague-Dawley rats.
    Archiv fur Geschwulstforschung, 1990, Volume: 60, Issue:2

    Topics: Animals; Cholesterol; Dietary Fats; Female; Lipid Metabolism; Lipids; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1990
Estrone sulfate stimulates growth of nitrosomethylurea-induced breast carcinoma in vivo in the rat.
    International journal of cancer, 1990, Jul-15, Volume: 46, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Estradiol; Estrone; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Inbred Strains; Time Factors

1990
Reduction in mammary tumorigenesis in the rat by cabbage and cabbage residue.
    Carcinogenesis, 1990, Volume: 11, Issue:7

    Topics: Animals; Body Weight; Brassica; Diet; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors

1990
Modulation of cytosolic sexual steroid receptors in autochthonous methylnitrosourea-induced rat mammary carcinoma following application of 2-chloroethylnitrosocarbamoyl-L-alanine linked to oestradiol or dihydrotestosterone.
    British journal of cancer, 1990, Volume: 62, Issue:1

    Topics: Animals; Antineoplastic Agents; Dihydrotestosterone; Estradiol; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Estradiol; Receptors, Steroid

1990
Inhibition of growth of established N-methyl-N-nitrosourea-induced mammary cancer in rats by retinoic acid and ovariectomy.
    Cancer research, 1990, Sep-15, Volume: 50, Issue:18

    Topics: Animals; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Inbred Strains; Tretinoin; Vitamin E

1990
Distribution of developmental markers in rat mammary tumors induced by N-nitrosomethylurea.
    Cancer research, 1986, Volume: 46, Issue:10

    Topics: Animals; Antigens, Surface; Cell Differentiation; Female; Keratins; Mammary Neoplasms, Experimental; Methylnitrosourea; Myosins; Rats; Rats, Inbred Strains; Thy-1 Antigens

1986
Stochastic development of invasive potential in rat mammary tumors induced by N-methyl-N-nitrosourea.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:22

    Topics: Animals; Antibodies, Monoclonal; Keratins; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Invasiveness; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Stochastic Processes

1988
Reversion toward an earlier stage of differentiation and loss of polarity during progression of N-methyl-N-nitrosourea-induced rat mammary tumours.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:23

    Topics: Animals; Cell Differentiation; Fluorescent Antibody Technique; Gene Expression Regulation; Genes; Keratins; Laminin; Mammary Neoplasms, Experimental; Methylnitrosourea; Microfilament Proteins; Microvilli; Rats; Rats, Inbred WF

1988
Evaluation of spin labeled TEPA and CCNU analogs against osteosarcoma and MNU-induced mammary carcinoma of the SD-rat.
    Archiv fur Geschwulstforschung, 1989, Volume: 59, Issue:4

    Topics: Animals; Antineoplastic Agents; Azirines; Bone Neoplasms; Cyclic N-Oxides; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Nitrosourea Compounds; Osteosarcoma; Rats; Rats, Inbred Strains; Triethylenephosphoramide

1989
Effect of human recombinant tumour necrosis factor and rat gamma interferon on nitrosomethylurea-induced mammary tumours.
    British journal of cancer, 1989, Volume: 59, Issue:2

    Topics: Animals; Combined Modality Therapy; Female; Humans; Interferon-gamma; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Recombinant Proteins; Tumor Necrosis Factor-alpha

1989
Phenotypic variability of chemically induced primary rat mammary tumors.
    Neoplasma, 1989, Volume: 36, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenotype; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Receptors, Estrogen; Sarcoma, Experimental

1989
Antitumor activity of the progesterone antagonists ZK 98.299 and RU 38.486 in the hormone-dependent MXT mammary tumor model of the mouse and the DMBA- and the MNU-induced mammary tumor models of the rat.
    European journal of cancer & clinical oncology, 1989, Volume: 25, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrenes; Female; Gonanes; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mifepristone; Neoplasms, Hormone-Dependent; Progesterone; Rats; Rats, Inbred Strains

1989
Differential effects of tranylcypromine and imidazole on mammary carcinogenesis in rats fed low and high fat diets.
    Cancer research, 1989, Jun-15, Volume: 49, Issue:12

    Topics: Animals; Cyclooxygenase Inhibitors; Dietary Fats; Female; Imidazoles; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Thromboxane-A Synthase; Tranylcypromine

1989
Antitumor activity of the antiprogestins ZK 98.299 and RU 38.486 in hormone dependent rat and mouse mammary tumors: mechanistic studies.
    Breast cancer research and treatment, 1989, Volume: 14, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Gonanes; Mammary Neoplasms, Experimental; Methylnitrosourea; Mifepristone; Neoplasm Transplantation; Organ Size; Ovariectomy; Ovary; Rats; Rats, Inbred Strains; Uterus; Vagina

1989
Chemopreventive efficacy of combined retinoid and tamoxifen treatment following surgical excision of a primary mammary cancer in female rats.
    Cancer research, 1989, Aug-15, Volume: 49, Issue:16

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation, Preclinical; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tamoxifen; Tretinoin

1989
Suppression of rat mammary cancer development by N-(4-hydroxyphenyl)retinamide (4-HPR) following surgical removal of first palpable tumor.
    Carcinogenesis, 1989, Volume: 10, Issue:9

    Topics: Administration, Oral; Animals; Diet; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tretinoin

1989
Therapeutic effect of N-(4-hydroxyphenyl)retinamide on N-methyl-N-nitrosourea-induced rat mammary cancer.
    Cancer letters, 1989, Volume: 47, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Remission Induction; Tamoxifen; Tretinoin

1989
[In vitro study of estradiol-linked nitrosourea in breast cancers in the mouse, rat and human: interspecies comparison].
    Wiener klinische Wochenschrift, 1989, Feb-17, Volume: 101, Issue:4

    Topics: Animals; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Cell Division; Cell Survival; Colony-Forming Units Assay; Estradiol; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Transplantation; Nitrogen Mustard Compounds; Rats; Rats, Inbred Strains; Species Specificity; Tumor Cells, Cultured; Tumor Stem Cell Assay

1989
Possible role for vitamin D in controlling breast cancer cell proliferation.
    Lancet (London, England), 1989, Jan-28, Volume: 1, Issue:8631

    Topics: Adult; Aged; Aged, 80 and over; Animals; Breast Neoplasms; Cell Differentiation; Cell Division; Female; Humans; Hydroxycholecalciferols; Mammary Neoplasms, Experimental; Methylnitrosourea; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Rats; Receptors, Calcitriol; Receptors, Steroid; Time Factors; Tumor Cells, Cultured; Vitamin D

1989
Isolation and characterization of clonal cell lines from a transplantable metastasizing rat mammary tumor, TR2CL.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Female; Histocytochemistry; Keratins; Laminin; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Rats; Rats, Inbred F344

1985
Estrous cycle status alters N-methyl-N-nitrosourea (NMU)-induced rat mammary tumor growth and regression.
    Cancer letters, 1989, Volume: 48, Issue:3

    Topics: Animals; Cell Nucleus; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estrogen

1989
The prevention of nitrosomethylurea-induced mammary tumors by d-limonene and orange oil.
    Carcinogenesis, 1989, Volume: 10, Issue:4

    Topics: Animals; Cyclohexenes; Female; Limonene; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred WF; Terpenes; Time Factors

1989
Dietary protein enhanced mammary ornithine decarboxylase activity and tumorigenesis in rats.
    The Journal of nutrition, 1989, Volume: 119, Issue:4

    Topics: Adenocarcinoma; Animals; Dietary Proteins; Epithelium; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Ornithine Decarboxylase; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine

1989
Different effects of cyclophosphamide in vivo and phosphamide mustard in vitro on two cell clones of chemically induced mammary carcinoma of the rat.
    Journal of cancer research and clinical oncology, 1989, Volume: 115, Issue:2

    Topics: Animals; Clone Cells; Cyclophosphamide; Drug Evaluation, Preclinical; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Rats; Tumor Cells, Cultured

1989
Metabolism of retinol and retinoic acid in N-methyl-N-nitrosourea-induced mammary carcinomas in rats.
    Cancer research, 1989, Jan-01, Volume: 49, Issue:1

    Topics: Acyltransferases; Animals; Carboxylic Ester Hydrolases; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Retinol O-Fatty-Acyltransferase; Tretinoin; Vitamin A

1989
Anticancer efficacy of 2-chloroethylnitrosocarbamoyl derivatives of L-alanine, glycine, their di- and tripeptide homologues and the respective amides in methylnitrosourea-induced rat mammary carcinoma.
    British journal of cancer, 1989, Volume: 59, Issue:3

    Topics: Alanine; Animals; Antineoplastic Agents; Female; Glycine; Mammary Neoplasms, Experimental; Methylnitrosourea; Mustard Compounds; Nitrosourea Compounds; Rats; Rats, Inbred Strains

1989
Retinoid-tamoxifen interaction in mammary cancer chemoprevention.
    Carcinogenesis, 1986, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Dose-Response Relationship, Drug; Drug Synergism; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen; Tretinoin

1986
N-nitroso-N-methylurea-induced mammary carcinogenesis: effect of prolactin on expression of Ia antigen by tumor cells.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Female; Histocompatibility Antigens Class II; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prolactin

1986
1,25-Dihydroxyvitamin D3 binding in estrogen-responsive rat breast tumor.
    Endocrinology, 1986, Volume: 119, Issue:1

    Topics: Animals; Calcitriol; Cell Line; Estrogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Rats; Receptors, Calcitriol; Receptors, Steroid

1986
Anticancer activity of bisphosphonic acids in methylnitrosourea-induced mammary carcinoma of the rat--benefit of combining bisphosphonates with cytostatic agents.
    Investigational new drugs, 1988, Volume: 6, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Diphosphonates; Female; Mammary Neoplasms, Experimental; Melphalan; Methylnitrosourea; Mutagenicity Tests; Nitrogen Mustard Compounds; Pamidronate; Rats; Rats, Inbred Strains; Salmonella typhimurium

1988
Autocrine stimulation by estradiol-regulated growth factors of rat hormone-responsive mammary cancer: interaction with the polyamine pathway.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Animals; Cells, Cultured; Culture Media; Eflornithine; Estradiol; Female; Growth Substances; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Weight; Ornithine; Polyamines; Rats; Rats, Inbred Strains

1986
Effect of tamoxifen and D,L-2-difluoromethylornithine on the growth, ornithine decarboxylase activity and polyamine content of mammary carcinomas induced by 1-methyl-1-nitrosourea.
    Carcinogenesis, 1986, Volume: 7, Issue:5

    Topics: Animals; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ornithine; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred Strains; Tamoxifen

1986
Binding of estrogen receptor from N-nitrosomethylurea-induced rat mammary tumors to nuclei.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:2

    Topics: Animals; Cell Nucleus; Edetic Acid; Female; Hot Temperature; Magnesium; Mammary Neoplasms, Experimental; Mesothelin; Methylnitrosourea; Molybdenum; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estrogen; Time Factors

1986
Genetic control of resistance to chemically induced mammary adenocarcinogenesis in the rat.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Alleles; Animals; Crosses, Genetic; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Species Specificity

1986
Polyamines and autocrine control of tumor growth by prolactin in experimental breast cancer in culture.
    Endocrinology, 1986, Volume: 119, Issue:5

    Topics: Animals; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Drug Synergism; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplastic Stem Cells; Polyamines; Prolactin; Rats; Rats, Inbred Strains; Sheep; Spermidine

1986
Quantitation of nuclear aberrations as a screen for agents damaging to mammary epithelium.
    Carcinogenesis, 1986, Volume: 7, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Nucleus; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mutagenicity Tests

1986
Effect of D,L-2-difluoromethylornithine and endocrine manipulation on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea.
    Carcinogenesis, 1986, Volume: 7, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Polyamines; Rats; Rats, Inbred Strains; Tamoxifen

1986
In vitro transformation of mouse mammary epithelial cells grown serum-free inside collagen gels.
    Cancer research, 1987, Jan-01, Volume: 47, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Physiological Phenomena; Cell Transformation, Neoplastic; Cells, Cultured; Collagen; Epithelium; Female; Gels; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C

1987
Effects of progestins on growth of experimental breast cancer in culture: interaction with estradiol and prolactin and involvement of the polyamine pathway.
    Cancer research, 1987, Jun-15, Volume: 47, Issue:12

    Topics: Animals; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Drug Synergism; Eflornithine; Estradiol; Mammary Neoplasms, Experimental; Methylnitrosourea; Polyamines; Prolactin; Promegestone; Spermidine

1987
Importance of extended growth potential and growth factor independence on in vivo neoplastic potential of primary rat mammary carcinoma cells.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cholera Toxin; Epidermal Growth Factor; Female; Growth Substances; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Lew

1987
Nordihydroguaiaretic acid suppression of rat mammary carcinogenesis induced by N-methyl-N-nitrosourea.
    Cancer letters, 1987, Oct-30, Volume: 37, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Female; Mammary Neoplasms, Experimental; Masoprocol; Methylnitrosourea; Rats; Rats, Inbred Strains; Skin Neoplasms

1987
Role of polyamines in the synthesis of prolactin-regulated growth factors by experimental breast cancer in culture.
    Breast cancer research and treatment, 1987, Volume: 10, Issue:2

    Topics: Animals; Colony-Stimulating Factors; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Rats; Rats, Inbred Strains; Spermidine; Tumor Cells, Cultured

1987
Modulation of chemical carcinogenesis in rats by alkyl lysophospholipids.
    Lipids, 1987, Volume: 22, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Leukemia, Experimental; Lysophospholipids; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Organophosphates; Organophosphorus Compounds; Phospholipid Ethers; Rats; Rats, Inbred Strains

1987
Polyamines and autocrine control of N-nitrosomethylurea-induced rat mammary tumor growth in vitro by progesterone.
    Cancer research, 1988, Jun-01, Volume: 48, Issue:11

    Topics: Animals; Cell Division; Concanavalin A; Culture Media; Eflornithine; Mammary Neoplasms, Experimental; Methylnitrosourea; Polyamines; Progesterone; Rats; Spermidine; Steroids; Trypsin; Tumor Stem Cell Assay

1988
Role of polyamines in the growth of hormone-responsive experimental breast cancer in vivo.
    Breast cancer research and treatment, 1988, Volume: 11, Issue:3

    Topics: Animals; Biogenic Polyamines; Body Weight; Dose-Response Relationship, Drug; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Putrescine; Rats; Rats, Inbred Strains

1988
Inhibition of 7,12-dimethylbenz(a)anthracene- and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin.
    Cancer research, 1988, Oct-15, Volume: 48, Issue:20

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet; Female; Flavonoids; Mammary Neoplasms, Experimental; Methylnitrosourea; Quercetin; Rats; Rats, Inbred Strains; Weight Gain

1988
Effect of age on dose-response relationship in carcinogenesis induced by single administration of N-nitrosomethylurea in female rats.
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:6

    Topics: Age Factors; Alkylation; Animals; DNA; DNA Repair; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Species Specificity

1988
Independent molecular pathways in initiation and loss of hormone responsiveness of breast carcinomas.
    Science (New York, N.Y.), 1988, Apr-22, Volume: 240, Issue:4851

    Topics: Animals; Breast Neoplasms; Cell Line; Estrogens; Gene Expression Regulation; Genes, ras; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Receptors, Estrogen

1988
Serotherapy of cancer: cellular changes in primary rat mammary carcinomas after infusion of syngeneic sera absorbed with protein A-Sepharose.
    International journal of cancer, 1988, Jul-15, Volume: 42, Issue:1

    Topics: Animals; Antibodies; Blood Cell Count; Chromatography, Affinity; Complement Activation; Complement C3; Complement C5; Complement C5a; Cytotoxicity, Immunologic; Female; Immunization, Passive; Immunoenzyme Techniques; Inflammation; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitotic Index; Rats; Sepharose

1988
Anticarcinogenic activity of quinacrine in the rat mammary gland.
    Carcinogenesis, 1988, Volume: 9, Issue:1

    Topics: Animals; Diet; Dose-Response Relationship, Drug; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Quinacrine; Rats; Rats, Inbred Strains

1988
Activation of the estrogen receptor from N-nitrosomethylurea-induced rat mammary tumors.
    Journal of steroid biochemistry, 1988, Volume: 29, Issue:1

    Topics: Animals; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Female; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosourea; Molybdenum; Rats; Rats, Inbred Strains; Receptors, Estrogen

1988
Kinetic and morphometric responses of heterogeneous populations of experimental breast cancer cells in vivo.
    Cancer research, 1988, Jun-01, Volume: 48, Issue:11

    Topics: Animals; Cell Division; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Perphenazine; Rats; Rats, Inbred Strains

1988
Alpha 2 interferon in the prevention of N-nitroso-methyl urea induced breast cancer in rats.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1988, Volume: 14, Issue:3

    Topics: Animals; Female; Interferon Type I; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1988
Comparison of alkaline phosphatase activity in normal, lactating and neoplastic rat mammary tissue.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1988, Volume: 89, Issue:4

    Topics: Alkaline Phosphatase; Animals; Binding, Competitive; Bromocriptine; Female; Isoenzymes; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Pregnancy; Rats; Rats, Inbred Strains

1988
Comparison of in vivo and in vitro activity of estrogen-linked nitrosoureas in methylnitrosourea-induced rat mammary carcinoma.
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:3

    Topics: Animals; Antineoplastic Agents; Colony-Forming Units Assay; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrogen Mustard Compounds; Rats; Statistics as Topic; Tumor Stem Cell Assay

1988
Influence of dietary fat, caloric restriction, and voluntary exercise on N-nitrosomethylurea-induced mammary tumorigenesis in rats.
    Cancer research, 1988, Aug-01, Volume: 48, Issue:15

    Topics: Animals; Body Composition; Body Weight; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Exertion; Rats; Rats, Inbred F344

1988
In vitro evaluation of an estradiol-linked nitrosourea in mammary carcinomas of mouse, rat and man.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:6

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Estradiol; Ethylnitrosourea; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Middle Aged; Nitrogen Mustard Compounds; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Tumor Stem Cell Assay

1988
Neoplastic transformation of mouse mammary epithelial cells by in vitro exposure to N-methyl-N-nitrosourea.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:2

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Precancerous Conditions

1988
[Effect of molybdenum and tungsten on mammary carcinogenesis in Sprague-Dawley (SD) rats].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1987, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Molybdenum; Rats; Rats, Inbred Strains; Tungsten

1987
Dietary fat and mammary cancer. I. Promoting effects of different dietary fats on N-nitrosomethylurea-induced rat mammary tumorigenesis.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1

    Topics: Animals; Body Weight; Cocarcinogenesis; Dietary Fats; Fatty Acids; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Oils; Rats; Rats, Inbred F344; Statistics as Topic; Time Factors

1986
Dietary fat and mammary cancer. II. Modulation of serum and tumor lipid composition and tumor prostaglandins by different dietary fats: association with tumor incidence patterns.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:1

    Topics: Animals; Cholesterol; Cocarcinogenesis; Dietary Fats; Dinoprost; Dinoprostone; Fatty Acids; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Oils; Phospholipids; Prostaglandins; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Rats; Rats, Inbred F344; Triglycerides

1986
Immunocytochemical localization of RasHa p21 in normal and neoplastic cells in fixed tissue sections from Harvey sarcoma virus-infected mice.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Avidin; Biotin; Fluorescent Antibody Technique; Harvey murine sarcoma virus; Histocytochemistry; Liver Neoplasms; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Oncogene Protein p21(ras); Rats; Rats, Inbred F344; Sarcoma, Experimental; Sheep; Skin Neoplasms

1986
Comparison between the effects of dietary fat level and of calorie intake on methylnitrosourea-induced mammary carcinogenesis in female SD rats.
    International journal of cancer, 1987, Jun-15, Volume: 39, Issue:6

    Topics: Animals; Body Weight; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1987
The influence of different levels of dietary fat on the incidence and growth of MNU-induced mammary carcinoma in rats.
    Nutrition and cancer, 1987, Volume: 9, Issue:4

    Topics: Animals; Body Weight; Cholesterol; Dietary Fats; Female; Lipoproteins; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Triglycerides

1987
Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Animals; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Time Factors; Uterus

1987
Therapeutic ratio of mono or combination bacterial lipopolysaccharide therapy in methylnitrosourea-induced rat mammary carcinoma.
    Journal of cancer research and clinical oncology, 1987, Volume: 113, Issue:5

    Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Dose-Response Relationship, Immunologic; Female; Lipopolysaccharides; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1987
The analysis of cancer chemoprevention experiments.
    Biometrics, 1987, Volume: 43, Issue:3

    Topics: Animals; Biometry; Diterpenes; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Theoretical; Rats; Research Design; Retinyl Esters; Vitamin A

1987
Effects of vitamin A and E supplementation to diets containing two different fat levels on methylnitrosourea-induced mammary carcinogenesis in female SD-rats.
    British journal of cancer, 1987, Volume: 56, Issue:4

    Topics: Animals; Body Weight; Dietary Fats; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Vitamin A; Vitamin E

1987
Dietary protein, enhancement of N-nitrosomethylurea-induced mammary carcinogenesis, and their effect on hormone regulation in rats.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: alpha-Methyltyrosine; Animals; Body Weight; Dietary Fats; Dietary Proteins; Energy Intake; Estrus; Female; Growth Hormone; Mammary Neoplasms, Experimental; Methylnitrosourea; Methyltyrosines; Prolactin; Rats

1986
Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Dihydrotestosterone; Female; Humans; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Ovariectomy; Rats; Tamoxifen

1986
Evaluation of the effect of glucan on hepatic, renal and mammary tumorigenesis in rats.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 52, Issue:3

    Topics: Animals; Diethylnitrosamine; Female; Glucans; Glucose; Hepatectomy; Kidney Neoplasms; Liver Neoplasms; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenobarbital; Rats; Rats, Inbred Strains

1986
Polyamines and hormonal regulation of N-nitrosomethylurea-induced rat mammary tumor growth in vivo.
    Cancer research, 1986, Volume: 46, Issue:10

    Topics: Animals; Estrogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen

1986
Influence of perinatal nicotine administration on transplacental carcinogenesis in Sprague Dawley rats by N-methylnitrosourea.
    British journal of cancer, 1987, Volume: 55, Issue:1

    Topics: Animals; Female; Male; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasms, Experimental; Nervous System Neoplasms; Nicotine; Pregnancy; Rats; Rats, Inbred Strains

1987
Estrogen-linked 2-chloroethylnitrosoureas: anticancer efficacy in MNU-induced rat mammary carcinoma, uterine activity in mice and receptor interactions.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:10

    Topics: Animals; Antineoplastic Agents; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Nitrosourea Compounds; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains; Receptors, Estrogen; Uterus

1986
Lack of effect of indomethacin on the growth of N-nitrosomethylurea-induced rat mammary tumors.
    Revista espanola de oncologia, 1985, Volume: 32, Issue:1

    Topics: Animals; Female; Indomethacin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1985
Effect of pregnancy and nursing on the growth of metastases from N-nitroso-N-methylurea-induced mammary carcinomas.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:1

    Topics: Animals; Female; Lactation; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Pregnancy; Pregnancy, Animal; Rats; Time Factors

1985
Effects of molybdenum and tungsten on mammary carcinogenesis in SD rats.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:2

    Topics: Animals; Body Weight; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Molybdenum; Pregnancy; Rats; Rats, Inbred Strains; Tungsten

1985
Chemoprevention of N-nitroso-N-methylurea-induced mammary cancers by pretreatment with 17 beta-estradiol and progesterone.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:4

    Topics: Adenocarcinoma; Animals; Drug Therapy, Combination; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Progesterone; Rats

1985
Polyamines as mediators of the effect of prolactin and growth hormone on the growth of N-nitroso-N-methylurea-induced rat mammary tumor cultured in vitro in soft agar.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:4

    Topics: Agar; Animals; Cell Division; Cells, Cultured; Female; Growth Hormone; Mammary Neoplasms, Experimental; Methylnitrosourea; Polyamines; Prolactin; Rats; Rats, Inbred Strains

1985
Dietary effects of menhaden oil on the growth and membrane lipid composition of rat mammary tumors.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:5

    Topics: Animals; Autopsy; Corn Oil; Dietary Fats; Fatty Acids, Unsaturated; Female; Fish Oils; Mammary Neoplasms, Experimental; Membrane Lipids; Methylnitrosourea; Microsomes; Microsomes, Liver; Oils; Rats; Rats, Inbred BUF

1985
Effect of concentration of D,L-2-difluoromethylornithine on murine mammary carcinogenesis.
    Cancer research, 1985, Volume: 45, Issue:3

    Topics: Animals; Antineoplastic Agents; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ornithine; Putrescine; Rats; Rats, Inbred Strains

1985
Effects of diazoxide-induced reversible diabetes on chemically induced autochthonous mammary carcinomas in Sprague-Dawley rats.
    International journal of cancer, 1985, Mar-15, Volume: 35, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diazoxide; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Flow Cytometry; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors

1985
Chemical induction of ovarian tumors in rats.
    Gynecologic oncology, 1985, Volume: 21, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Carcinoma, Squamous Cell; Female; Fenitrothion; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovarian Neoplasms; Rats; Uterine Neoplasms

1985
Carcinogenic responses to chemicals applied directly to rat mammary glands in situ.
    Carcinogenesis, 1985, Volume: 6, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1985
The inhibitory effect of 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) on estrogen-dependent mammary tumors.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Indoles; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen

1985
Polyamines and estrogen control of growth of the NMU-induced rat mammary tumor.
    Breast cancer research and treatment, 1985, Volume: 5, Issue:2

    Topics: Animals; Body Weight; Cell Division; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Estradiol; Estrogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitoguazone; Nitrosourea Compounds; Ornithine; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred Strains; Tamoxifen

1985
Determination of the number of events required for mammary carcinogenesis in the Sprague-Dawley female rat.
    Cancer research, 1985, Volume: 45, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Biological; Oncogenes; Probability; Rats; Rats, Inbred Strains

1985
A multi-path theory of chemical carcinogenesis in the rat mammary gland.
    Progress in clinical and biological research, 1985, Volume: 172A

    Topics: Animals; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Biological; Oncogenes; Rats; Rats, Inbred Strains

1985
Influence of selenium on the growth of N-nitrosomethylurea-induced mammary tumor cells in culture.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Division; Cells, Cultured; DNA Replication; Female; Kinetics; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Proteins; Rats; Rats, Inbred BUF; Selenium

1985
Estrous cycle modification of rat mammary tumor induction by a single dose of N-methyl-N-nitrosourea.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: Animals; Cell Nucleus; Cytosol; DNA; Estrus; Female; Flow Cytometry; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Estrogen

1985
Effect of energy intake on the promotion of mammary carcinogenesis by dietary fat.
    Nutrition and cancer, 1985, Volume: 7, Issue:1-2

    Topics: Animals; Dietary Fats; Energy Intake; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains

1985
Influence of experimental diets on hepatic glutathione levels in rats with methylnitrosourea-induced mammary carcinoma.
    Journal of cancer research and clinical oncology, 1985, Volume: 110, Issue:3

    Topics: Animals; Diet; Dietary Fats; Female; Glutathione; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Vitamin A; Vitamin E

1985
Effect of different diets on the ratio of plasma lipids/vitamin A and E in female Sprague-Dawley rats with MNU-induced mammary carcinomas.
    Archiv fur Geschwulstforschung, 1985, Volume: 55, Issue:6

    Topics: Animals; Diet; Dietary Fats; Female; Lipids; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Vitamin A; Vitamin E

1985
N,N'-dimethylnitrosourea-induced tumors in mice and Syrian hamsters.
    Acta medica Okayama, 1974, Volume: 28, Issue:5

    Topics: Animals; Cricetinae; Female; Injections, Subcutaneous; Lung Neoplasms; Lymphoma; Male; Mammary Neoplasms, Experimental; Mediastinal Neoplasms; Methylnitrosourea; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Retroviridae; Stomach Neoplasms; Thymus Neoplasms; Transplantation, Homologous

1974