methylnitrosourea has been researched along with Carcinoma in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (32.79) | 18.7374 |
| 1990's | 16 (26.23) | 18.2507 |
| 2000's | 14 (22.95) | 29.6817 |
| 2010's | 9 (14.75) | 24.3611 |
| 2020's | 2 (3.28) | 2.80 |
| Authors | Studies |
|---|---|
| Acevedo, N; Bosland, MC; Prins, G; Schlicht, MJ; Soto, AM | 1 |
| Ansari, MN; Choudhary, A; Kaithwas, G; Kumar, D; Raj, R; Rastogi, S; Saeedan, AS; Singh, L; Singh, M | 1 |
| Ngalame, NN; Orihuela, RG; Person, RJ; Tokar, EJ; Waalkes, MP; Xu, Y | 1 |
| Bosland, MC | 1 |
| Caicedo-Granados, E; Galbraith, AR; Hartle, DE; Keel, S; Ondrey, FG; Schachern, MG; Wattenberg, LW; Wuertz, BR; Yueh, B | 1 |
| Zarbl, H; Zhang, X | 1 |
| Adorini, L; Atalla, N; Buckley, B; Conney, AH; Lee, HJ; Lin, X; Lou, YR; Lu, G; Maehr, H; Paul, S; Suh, N; Thomas, PE; Uskokovic, M; Yang, I; Zheng, X | 1 |
| Canpinar, G; Esendagli, G; Guc, D; Guc, MO; Gunel-Ozcan, A; Kansu, E; Yilmaz, G | 1 |
| Grubbs, CJ; Isayeva, T; Johnson, MD; Kern, FG; Mittal, AR; Ponnazhagan, S; Qu, Z; Ramanathan, HN; Thottassery, JV; Westbrook, L | 1 |
| Bougnoux, P; Hajjaji, N; Schubnel, V | 1 |
| Gediya, LK; Godbole, AM; Goss, PE; Hu, H; Njar, VC; Purushottamachar, P; Qi, S | 1 |
| Eichelberg, MR; Gould, MN; Haag, JD; Meilahn, AL; Muelbl, MJ; Sharma, D; Smits, BM | 1 |
| Bobrov, N; Bojková, B; Ekmekcioglu, C; Garajová, M; Jäger, W; Kassayová, M; Kisková, T; Orendáš, P; Thalhammer, T | 1 |
| Brtko, J; Liska, J; Macejova, D; Ondkova, S | 1 |
| El Bayoumy, K; Jiang, W; Manni, A; McGinley, JN; Thompson, HJ; Zhu, Z | 1 |
| Chan, FL; Chen, ZY; Cheung, SY; Choi, HL; Huang, Y; James, AE | 1 |
| Furukawa, F; Hirose, M; Imazawa, T; Natsume, M; Nishikawa, A; Okazaki, K; Osakabe, N; Yamagishi, M | 1 |
| Danbara, N; Hatano, T; Nikaido, Y; Pei, RJ; Tsubura, A; Yoshizawa, K; Yuri, T | 1 |
| Adlercreutz, H; Berger, MR; Lippert, TH; Mueck, AO; Seeger, H | 1 |
| Brinkley, WR; Edwards, DG; Goepfert, TM; Medina, D; Moreno-Smith, M; Pathak, S | 1 |
| Anderson, WR; Estensen, RD; Galbraith, AR; Hartle, DE; Jordan, MM; Ondrey, FG; Wattenberg, LW | 1 |
| Beagley, K; Goodall, CM; Horne, L; Noronha, RF | 1 |
| Narisawa, T; Sato, M; Takahashi, T; Tani, M | 1 |
| D'iachkovskaia, RF; Korman, DB; Krutova, TV; Shamaev, VI | 1 |
| Donahoe, R; Reznik, G; Reznik-Schüller, HM; Stinson, SF | 1 |
| Donahoe, R; Reznik, G; Stinson, SF | 1 |
| Carter, TH; Trombetta, LD; Weisbroth, SH; Zimmerman, JA | 1 |
| Parsa, I | 1 |
| Lilga, JC; Stinson, SF | 1 |
| Kawai, K; Kawamata, H; Okamoto, M; Oyasu, R | 1 |
| Bergoc, RM; Caro, RA; Davio, CA; Rivera, ES; Venturino, A | 1 |
| Fujimoto, N; Ito, A; Ogundigie, PO; Okamoto, T; Watanabe, H | 1 |
| Aldaz, CM; Chen, A; Gollahon, LS | 1 |
| Furihata, C; Hattori, M; Inada, K; Ishida, S; Ito, T; Nakanishi, H; Saito, M; Sakaki, Y; Tatematsu, M; Tei, H | 1 |
| Fukumoto, M; Nandi, S; Pascual, R; Shirai, K; Tsubura, A; Tsukamoto, T; Uemura, Y | 1 |
| Bosland, MC; Johnson, WD; Kelloff, GJ; Lubet, RA; McCormick, DL; Rao, KV; Steele, VE | 1 |
| Hirose, M; Shibutani, M; Shoda, T; Takada, K; Takahashi, M; Tamura, T; Toyoda, K; Uneyama, C | 1 |
| Jiang, W; Thompson, HJ; Zhu, Z | 1 |
| Biozzi, G; Bouthillier, Y; Covelli, V; Doria, G; Mouton, D; Pazzaglia, S; Pioli, C; Rebessi, S; Saran, A | 1 |
| Brtko, J; Galbavy, S; Liska, J; Macejova, D; Zlatos, J | 1 |
| García-González, MA; Morandeira, JR; Morandeira, MJ; Ucar, A | 1 |
| Chen, WD; Gerson, SL; Lee, K; Liu, L; Markowitz, SD; Qin, X; Zhou, H | 1 |
| Brtko, J; Líska, J; Macejová, D | 1 |
| Denlinger, RH; Koestner, A; Swenberg, JA | 1 |
| Bychkov, MB; Perevodchikova, NI; Starichkov, MS | 1 |
| Dement'eva, ND; Korman, DB | 1 |
| Corbett, TH; Griswold, DP; Peckham, JC; Roberts, BJ; Schabel, FM | 1 |
| Haas, H; Hilfrich, J; Kmoch, N; Mohr, U | 1 |
| Hasegawa, R; Imaida, K; Mori, T; Shirai, T; Tamano, S; Yamamoto, A | 1 |
| Fujimoto, N; Ito, A; Sakai, Y | 1 |
| Azuma, M; Momose, H; Oyasu, R; Uchida, K; Yura, Y | 1 |
| Alexander, RJ; Buxbaum, JN; Raicht, RF | 1 |
| Adlakha, H; Thompson, HJ | 1 |
| Barbacid, M; Kumar, R; Sukumar, S | 1 |
| Berger, MR; Kaufmann, M; Petru, E; Zeller, WJ | 1 |
| Oyasu, R; Samma, S | 1 |
| Aonuma, T | 1 |
| Gassner, G; Kunze, E | 1 |
| Bauer, K; Homma, Y; Oyasu, R; Ozono, S; Samma, S; Wallemark, CB | 1 |
| Iversen, OH; Kirkhus, B; Kristensen, A | 1 |
| Ohshima, M; Ward, JM | 1 |
61 other study(ies) available for methylnitrosourea and Carcinoma
| Article | Year |
|---|---|
Effects of perinatal exposure to bisphenol A on induction of prostate cancer in Sprague Dawley rats by MNU and testosterone.
Topics: Animals; Benzhydryl Compounds; Carcinogenesis; Carcinoma; Estradiol; Humans; Infant, Newborn; Male; Methylnitrosourea; Pregnancy; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Testosterone | 2023 |
Effect of Voacamine upon inhibition of hypoxia induced fatty acid synthesis in a rat model of methyln-nitrosourea induced mammary gland carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Body Weight; Carcinoma; Computer Simulation; Electrocardiography; Fatty Acids; Female; Heart Rate; Hypoxia-Inducible Factor-Proline Dioxygenases; Ibogaine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Metabolome; Methylnitrosourea; Neovascularization, Pathologic; Rats, Wistar; Tamoxifen | 2021 |
Recruitment of normal stem cells to an oncogenic phenotype by noncontiguous carcinogen-transformed epithelia depends on the transforming carcinogen.
Topics: Animals; Blotting, Western; Cadmium; Carcinogens; Carcinoma; Cell Line, Tumor; Cell Transformation, Neoplastic; Environmental Pollutants; Epithelial Cells; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinases; Methylnitrosourea; Mice; Mice, Nude; Neoplastic Stem Cells; Polymerase Chain Reaction; Prostatic Neoplasms; Transforming Growth Factor alpha | 2013 |
Testosterone treatment is a potent tumor promoter for the rat prostate.
Topics: Androgens; Animals; Carcinoma; Dose-Response Relationship, Drug; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Testosterone | 2014 |
N-methylnitrosourea–induced carcinoma as a model for laryngeal carcinogenesis.
Topics: Animals; Carcinogenesis; Carcinoma; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Instillation, Drug; Laryngeal Neoplasms; Laryngoscopy; Methylnitrosourea; Mice | 2014 |
Chemopreventive doses of methylselenocysteine alter circadian rhythm in rat mammary tissue.
Topics: Animals; Breast Neoplasms; Carcinoma; Cell Cycle Proteins; Chemoprevention; Circadian Rhythm; Cysteine; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Glands, Animal; Methylnitrosourea; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Period Circadian Proteins; Rats; Rats, Inbred F344; Selenium; Selenocysteine; Specific Pathogen-Free Organisms | 2008 |
Gemini vitamin D analogues inhibit estrogen receptor-positive and estrogen receptor-negative mammary tumorigenesis without hypercalcemic toxicity.
Topics: Animals; Calcitriol; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Female; Humans; Hypercalcemia; Incidence; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, SCID; Models, Biological; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Xenograft Model Antitumor Assays | 2008 |
Primary tumor cells obtained from MNU-induced mammary carcinomas show immune heterogeneity which can be modulated by low-efficiency transfection of CD40L gene.
Topics: Alkylating Agents; Animals; Animals, Outbred Strains; Carcinoma; CD40 Ligand; Cell Line, Tumor; Culture Media; Ethidium; Female; Fluorescent Dyes; Green Fluorescent Proteins; Immunohistochemistry; Liposomes; Mammary Neoplasms, Experimental; Methylnitrosourea; Mucin-1; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Transfection | 2009 |
High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1.
Topics: Animals; Antineoplastic Agents, Hormonal; Carcinogens; Carcinoma; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase Inhibitor p27; Drug Resistance, Neoplasm; Estradiol; Estrogens; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Animal; Methylnitrosourea; Mice; Mice, Transgenic; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tumor Cells, Cultured | 2009 |
Determinants of DHA incorporation into tumor tissue during dietary DHA supplementation.
Topics: Animals; Carcinoma; Dietary Fats; Dietary Supplements; Docosahexaenoic Acids; Fatty Acids; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Phospholipids; Rats; Rats, Sprague-Dawley; Tissue Distribution; Triglycerides | 2011 |
Anti-tumor effects of a novel retinoic acid metabolism blocking agent VN/14-1 in the N-methyl-N-nitrosourea-induced rat mammary carcinoma model and its effects on the uterus.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Density; Carcinoma; Cell Size; Drug Screening Assays, Antitumor; Estradiol; Female; Imidazoles; Lipid Metabolism; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Tretinoin; Tumor Burden; Uterus | 2012 |
Quantification of epithelial cell differentiation in mammary glands and carcinomas from DMBA- and MNU-exposed rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Biomarkers; Carcinoma; Cell Differentiation; Cell Division; Cell Membrane; Cell Proliferation; Epithelial Cells; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Biological; Rats; Up-Regulation | 2011 |
A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis.
Topics: Algorithms; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Carcinoma; Chemoprevention; Drug Evaluation, Preclinical; Estrogen Receptor alpha; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2012 |
Morphology of 1-methyl-1-nitrosourea induced rat mammary tumours after treatment with precursor of phytanic acid or its combination with vitamin D analogue.
Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Disease Progression; Drug Evaluation, Preclinical; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytanic Acid; Rats; Rats, Sprague-Dawley; Tumor Burden; Vitamin D | 2012 |
Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids.
Topics: Animals; Carcinogens; Carcinoma; Cell Proliferation; Cluster Analysis; Dietary Fats; Down-Regulation; Drug Evaluation, Preclinical; Fatty Acids, Omega-3; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Methylnitrosourea; Microarray Analysis; Models, Biological; Rats; Validation Studies as Topic | 2012 |
Spontaneous mammary tumors in aging Noble rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age of Onset; Animals; Carcinoma; Diethylstilbestrol; Drug Implants; Estradiol; Female; Fibroadenoma; Genetic Predisposition to Disease; Incidence; Male; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Neoplasm Transplantation; Ovariectomy; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Rodent Diseases; Species Specificity; Testosterone | 2003 |
Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model.
Topics: 1,2-Dimethylhydrazine; Animals; Anthocyanins; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Cacao; Carcinoma; Catechin; Diethylnitrosamine; Drug Administration Schedule; Drug Screening Assays, Antitumor; Flavonoids; Gastrointestinal Neoplasms; Injections, Intraperitoneal; Injections, Subcutaneous; Lung Neoplasms; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Phenols; Phytotherapy; Pituitary Neoplasms; Plant Extracts; Polymers; Proanthocyanidins; Rats; Rats, Inbred F344; Thyroid Neoplasms; Urogenital Neoplasms | 2003 |
Prepubertal zearalenone exposure suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis but causes severe endocrine disruption in female Sprague-Dawley rats.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovulation; Random Allocation; Rats; Rats, Sprague-Dawley; Sexual Maturation; Time Factors; Zearalenone | 2003 |
Urinary phytoestrogen excretion of rats bearing methylnitrosourea-induced mammary carcinoma in response to treatment with 2-methoxyestradiol.
Topics: 2-Methoxyestradiol; Animals; Carcinoma; Coumestrol; Estradiol; Female; Isoflavones; Lignans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytoestrogens; Rats; Rats, Sprague-Dawley | 2007 |
Loss of chromosomal integrity drives rat mammary tumorigenesis.
Topics: Animals; Antigens, Neoplasm; Aurora Kinase A; Aurora Kinases; Carcinoma; Cell Transformation, Neoplastic; Centrosome; Chromosomal Instability; Female; Karyotyping; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Polyploidy; Protein Serine-Threonine Kinases; Rats; Rats, Inbred WF | 2007 |
A method of producing carcinoma in upper aerodigestive tree and esophagus of the Syrian golden hamster using wounding and instillation of N-methylnitrosourea.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Chemoprevention; Cricetinae; Disease Models, Animal; Epithelium; Esophageal Neoplasms; Glottis; Laryngeal Neoplasms; Mesocricetus; Metaplasia; Methylnitrosourea; Mucous Membrane; Pharyngeal Neoplasms; Respiratory Mucosa; Trachea; Tracheal Neoplasms | 2007 |
Unusually high susceptibility of NZR/Gd rats to bladder cancer induction by low doses of nitrosomethylurea.
Topics: Animals; Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Disease Susceptibility; Female; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder Neoplasms; Urinary Catheterization | 1984 |
Chemoprevention of development of colonic adenomatosis and carcinomatosis with 5-fluorouracil and ftorafur on animal model.
Topics: Adenoma; Animals; Carcinoma; Colon; Colonic Neoplasms; Female; Fluorouracil; Methylnitrosourea; Neoplasms, Experimental; Rats; Tegafur | 1980 |
[Changes in the proliferative activity of human breast cancer cells cultivated in vivo in diffusion chambers in response to antineoplastic agents].
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma; Diazonium Compounds; Drug Evaluation, Preclinical; Humans; Methylnitrosourea; Mice; Mice, Inbred CBA; Mitotic Index; Neoplasm Transplantation; Nitrosourea Compounds; Succinates; Thiotepa; Transplantation, Heterologous | 1981 |
Spindle cell carcinoma of the hamster trachea induced by N-methyl-N-nitrosourea.
Topics: Animals; Carcinoma; Cricetinae; Laryngeal Neoplasms; Male; Mesocricetus; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Tracheal Neoplasms | 1983 |
Effect of three retinoids on tracheal carcinogenesis with N-methyl-N-nitrosourea in hamsters.
Topics: Amyloidosis; Animals; Carcinoma; Cricetinae; Isotretinoin; Male; Mesocricetus; Methylnitrosourea; Neoplasms, Experimental; Precancerous Conditions; Probability; Tracheal Neoplasms; Tretinoin | 1981 |
Pancreatic carcinoma induced by N-methyl-N'-nitrosourea in aged mice.
Topics: Age Factors; Animals; Carcinoma; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Microscopy, Electron; Neoplasms, Experimental; Nitrosourea Compounds; Pancreas; Pancreatic Neoplasms | 1982 |
Identification of human acinar cell carcinoma by monoclonal antibody and in vitro differentiation.
Topics: Adult; Animals; Antibodies, Monoclonal; Antigens, Surface; Carcinoma; Cell Membrane; Humans; Methylnitrosourea; Mice; Mice, Nude; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Organ Culture Techniques; Pancreatic Neoplasms | 1982 |
Morphogenesis of neoplasms induced in the hamster trachea with N-methyl-N-nitrosourea.
Topics: Animals; Carcinoma; Cricetinae; Epithelium; Hyperplasia; Male; Mesocricetus; Methylnitrosourea; Morphogenesis; Papilloma; Time Factors; Tracheal Neoplasms | 1980 |
Enhancement of transformation in vitro of a nontumorigenic rat urothelial cell line by interleukin 6.
Topics: Animals; Antigens, CD; Carcinogens; Carcinoma; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Gene Expression Regulation, Neoplastic; In Vitro Techniques; Interleukin-1; Interleukin-6; Interleukin-8; Methylnitrosourea; Rats; Receptors, Interleukin; Receptors, Interleukin-6; RNA, Messenger; RNA, Neoplasm; Tumor Necrosis Factor-alpha; Urinary Bladder; Urinary Bladder Neoplasms | 1995 |
Histamine receptors in an experimental mammary carcinoma.
Topics: Animals; Carcinoma; Cyclic AMP; Histamine Antagonists; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Histamine | 1994 |
Inhibition of mammary tumors by pretreatment with 17 beta-estradiol in F344 rats induced with N-methyl-N-nitrosourea.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Rats; Rats, Inbred F344 | 1994 |
Systematic HRAS amplification in ovary-independent mammary tumors: correlation with progressively anaplastic phenotypes.
Topics: Adenocarcinoma; Alleles; Animals; Antigens, Neoplasm; Carcinoma; Chromosome Banding; DNA, Neoplasm; Female; Gene Amplification; Genes, ras; In Situ Hybridization; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenotype; Rats; Rats, Inbred BUF | 1993 |
Rare occurrence of ras and p53 gene mutations in mouse stomach tumors induced by N-methyl-N-nitrosourea.
Topics: Adenoma; Animals; Carcinoma; Genes, p53; Genes, ras; Male; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mutagenesis; Stomach Neoplasms | 1997 |
Synergistic effect of MNU and DMBA in mammary carcinogenesis and H-ras activation in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Drug Synergism; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Point Mutation; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley | 1997 |
Chemoprevention of rat prostate carcinogenesis by early and delayed administration of dehydroepiandrosterone.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Carcinoma; Cyproterone Acetate; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone; Time Factors | 1999 |
Tumor-promoting activities of hydroquinone and 1,1-dimethylhydrazine after initiation of newborn mice with 1-methyl-1-nitrosourea.
Topics: Adenoma; Animals; Animals, Newborn; Body Weight; Carcinogens; Carcinoma; Dimethylhydrazines; Female; Hydroquinones; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Methylnitrosourea; Mice; Mice, Inbred ICR; Mutagens; Organ Size | 1999 |
Effect of energy restriction on tissue size regulation during chemically induced mammary carcinogenesis.
Topics: Adipose Tissue; Animals; Apoptosis; Carcinoma; Cell Division; Energy Metabolism; Female; Food Deprivation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 1999 |
Skin tumorigenesis by initiators and promoters of different chemical structures in lines of mice selectively bred for resistance (Car-r) or susceptibility (Car-s) to two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinoma; Methylnitrosourea; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Histopathology of mammary tumours in female rats treated with 1-methyl-1-nitrosourea.
Topics: Adenocarcinoma; Animals; Carcinoma; Carcinoma in Situ; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 2000 |
A new model for the induction of tumours in the forestomach of rats by N-methyl-N-nitrosourea.
Topics: Animals; Carcinogens; Carcinoma; Female; Male; Methylnitrosourea; Papilloma; Rats; Rats, Wistar; Stomach Neoplasms; Time Factors | 2000 |
MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice.
Topics: Alkylating Agents; Animals; Carcinoma; DNA Methylation; DNA, Viral; Female; Genes, ras; Lymphoma, T-Cell; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylnitrosourea; Mice; Mice, Transgenic; Mutation; Promoter Regions, Genetic; Receptor, ErbB-2; Receptor, ErbB-3; RNA, Neoplasm; Terminal Repeat Sequences | 2001 |
Mammary gland carcinoma-related increase of type I iodothyronine 5'-deiodinase activity in Sprague-Dawley rats.
Topics: Animals; Carcinogens; Carcinoma; Female; Iodide Peroxidase; Mammary Neoplasms, Animal; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Neoplasms in purebred boxer dogs following long-term administration of N-methyl-N-nitrosourea.
Topics: Animals; Carcinoma; Dogs; Female; Hemangioma; Intestinal Neoplasms; Intestine, Small; Lymphoma; Male; Methylnitrosourea; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Sarcoma, Experimental; Species Specificity; Time Factors | 1978 |
[Combined chemo-radiotherapy of small-cell cancer of the lung].
Topics: Adult; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Methotrexate; Methylnitrosourea; Middle Aged; Radiotherapy Dosage | 1977 |
[Nitrosomethylurea in polychemotherapy of malignant tumors].
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Lung Neoplasms; Methylnitrosourea; Neoplasms; Nitrosourea Compounds | 1977 |
Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.
Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma; Chemical Phenomena; Chemistry; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosomethylurethane; Transplantation, Homologous | 1975 |
Specific carcinogenic effect of N-methyl-N-nitrosourea on the midventral sebaceous gland of the gerbil (Meriones unguiculatus).
Topics: Adenoma; Animals; Carcinoma; Female; Gerbillinae; Injections, Intravenous; Lethal Dose 50; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Sebaceous Gland Neoplasms; Sex Factors | 1975 |
Lack of synergism among DMAB, BOP, and MNU in induction of carcinomas of the rat ventral prostate.
Topics: Aminobiphenyl Compounds; Animals; Carcinogens; Carcinoma; Drug Synergism; Male; Methylnitrosourea; Nitrosamines; Prostatic Neoplasms; Rats; Rats, Inbred F344 | 1992 |
Increase in estrogen receptor levels in MNU-induced thyroid tumors in LE rats.
Topics: Adenoma; Animals; Carcinoma; Estrogens; Female; Hyperplasia; Iodine; Male; Methylnitrosourea; Organ Size; Pituitary Gland; Propylthiouracil; Rats; Rats, Inbred Strains; Receptors, Estrogen; Thyroid Gland; Thyroid Neoplasms; Thyrotropin | 1992 |
ras gene alterations in invasive and non-invasive rat bladder carcinomas induced by N-methyl-N-nitrosourea.
Topics: Animals; Blotting, Southern; Carcinoma; Cell Line; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Methylnitrosourea; Mice; Mice, Nude; Neoplasm Invasiveness; Nucleic Acid Hybridization; Oncogene Protein p21(ras); Rats; Rats, Inbred F344; Transfection; Urinary Bladder Neoplasms | 1991 |
Enhanced expression of oncogene-encoded mRNA in a rat model of colon cancer.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Cholic Acid; Cholic Acids; Colon; Colonic Neoplasms; Gene Expression; Male; Methylnitrosourea; Rats; Rats, Inbred F344; RNA, Messenger | 1991 |
Dose-responsive induction of mammary gland carcinomas by the intraperitoneal injection of 1-methyl-1-nitrosourea.
Topics: Animals; Carcinoma; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Survival Analysis; Time Factors | 1991 |
Activation of ras oncogenes preceding the onset of neoplasia.
Topics: Adenofibroma; Animals; Animals, Newborn; Base Sequence; Carcinoma; Cell Transformation, Neoplastic; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Rats; Rats, Inbred Strains; Sexual Maturation; Time Factors | 1990 |
[In vitro study of estradiol-linked nitrosourea in breast cancers in the mouse, rat and human: interspecies comparison].
Topics: Animals; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Cell Division; Cell Survival; Colony-Forming Units Assay; Estradiol; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Transplantation; Nitrogen Mustard Compounds; Rats; Rats, Inbred Strains; Species Specificity; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
Conversion from low grade to high grade of rat urinary bladder carcinomas.
Topics: Animals; Carcinoma; Male; Methylnitrosourea; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1988 |
[Histopathologic study of rapidly induced colonic carcinoma in rats by N-methyl-N-nitrosourea--with special reference to histogenesis].
Topics: Animals; Carcinoma; Colonic Neoplasms; DNA, Neoplasm; Intestinal Mucosa; Male; Methylnitrosourea; Neoplasm Invasiveness; Rats | 1986 |
Modification of N-methyl-N-nitrosourea-induced urinary bladder carcinogenesis in rats following stimulation of urothelial proliferation by a partial cystectomy.
Topics: Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Epithelial Cells; Epithelium; Female; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1986 |
Induction of high-grade, high-stage carcinomas in the rat urinary bladder.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelium; Flow Cytometry; Hyperplasia; Methylnitrosourea; Neoplasm Transplantation; Nitrosamines; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Carcinogenic doses of methylnitrosourea induce dose response related delay in transit through S and G2 phases in mouse epidermis: a cell kinetic study.
Topics: Adenoma; Animals; Carcinoma; DNA Replication; Flow Cytometry; Interphase; Kinetics; Lung Neoplasms; Methylnitrosourea; Mice; Mice, Hairless; Skin; Skin Neoplasms; Thymidine | 1987 |
Dietary iodine deficiency as a tumor promoter and carcinogen in male F344/NCr rats.
Topics: Animals; Body Weight; Carcinoma; Iodine; Male; Methylnitrosourea; Neoplasm Transplantation; Organ Size; Pituitary Neoplasms; Rats; Thyroid Neoplasms | 1986 |