methylnitrosourea has been researched along with Cancer of Colon in 101 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (47.52) | 18.7374 |
| 1990's | 33 (32.67) | 18.2507 |
| 2000's | 17 (16.83) | 29.6817 |
| 2010's | 3 (2.97) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atawodi, SE; Iliemene, UD | 1 |
| Budak, M; Kalkan, T; Korpinar, MA; Tuncel, H | 1 |
| Berriel, E; Bollati-Fogolín, M; Chiale, C; Chiribao, ML; Festari, MF; Freire, T; Mazal, D; Medeiros, A; Osinaga, E; Rabinovich, GA; Robello, C; Rondán, M; Ubillos, L | 1 |
| Hirata, K; Inoue, Y; Minagawa, N; Nagata, J; Nagata, N; Nakayama, Y; Onitsuka, K; Sako, T; Shibao, K; Yamaguchi, K | 1 |
| Boring, D; Grubbs, CJ; Juliana, MM; Kopelovich, L; Lubet, RA; Patlolla, J; Rao, CV; Steele, VE; Zhang, Y | 1 |
| Ali, EM; Amin, AA; Helal, TE; Khalifa, AA; Mabrouk, GM; Moselhy, SS; Zohny, SF | 1 |
| Cagatay, P; Kalkan, MT; Shimamoto, F; Tuncel, H | 1 |
| Fukaura, Y; Narisawa, T | 3 |
| Bardwell, H; Campbell, FC; Crowe, P; Donnelly, ET; Hewer, A; Hoper, M; McCluggage, WG; Osborne, MR; Phillips, DH; Stevenson, M; Thomas, GA; Williams, ED | 1 |
| Mehta, RG; Murillo, G | 1 |
| Starling, JR; Syrjala, S; Weese, JL | 1 |
| Amato, DA; Cockerell, GL; Kriedemann, WL; O'Donnell, RW; Turnbull, BW | 1 |
| Anisimov, VN | 1 |
| Habs, M; Hermanek, P; Narisawa, T; Schmähl, D | 1 |
| Narisawa, T; Sano, M; Satoh, M; Takahashi, T | 1 |
| Locniskar, M; Nauss, KM; Newberne, PM; Sondergaard, D | 1 |
| Narisawa, T; Sato, M; Takahashi, T; Tani, M | 1 |
| Starling, JR; Turner, JH; Weese, JL | 1 |
| Cohen, BI; Deschner, EE; Fazzini, E; Raicht, RF; Sarwal, AN; Takahashi, M | 1 |
| Cohen, BI; Deschner, EE; Raicht, RF | 1 |
| Narisawa, T; Sano, M; Sato, M; Takahashi, T | 1 |
| Cohen, BI; Fazzini, E; Raicht, RF | 1 |
| Hirota, N; Katayama, S; Reddy, BS | 1 |
| Goto, A; Kudo, T; Narisawa, T; Sato, M; Takahashi, T; Tani, M | 1 |
| Amberger, H; Bachmann, U; Habs, M; Merz, R; Schmähl, D; Wagner, I | 1 |
| Cockerell, GL; O'Donnell, RW | 1 |
| Cohen, BI; Raicht, RF | 1 |
| Dean, J; Reznik, G; Ward, JM; Wenk, ML | 1 |
| Katayama, S; Lauber, J; Levenstein, MJ; Musser, TK; Reddy, M; Silverman, J; Weisburger, H; Zelenakas, K | 1 |
| Humphrey, LJ; Humphrey, M; McCarthy, RP; Volenec, FJ; Whitmore, S | 1 |
| Kohno, KI; Narisawa, T; Takahashi, T; Yamaguchi, T | 1 |
| Cohen, BI; Fazzini, EP; Raicht, RF; Sarwal, AN; Takahashi, M | 1 |
| Cockerell, GL; Kriedemann, WL; O'Donnell, RW; Perez, R | 1 |
| Kawamori, T; Kojima, T; Mori, H; Tanaka, T | 1 |
| Fukaura, Y; Ishikawa, C; Isoda, Y; Narisawa, T; Nishizawa, Y; Yazawa, K | 1 |
| Arai, M; Ishikawa, T; Nakatsuru, Y; Oda, H; Qin, X; Zarkovic, M | 1 |
| Ishikawa, T; Nakamura, T; Nakatsuru, Y; Oda, H; Qin, X; Shamsuddin, AM; Zarkovic, M | 1 |
| Bird, RP; Magnuson, BA | 1 |
| Kawaura, A; Nishikawa, M; Shimoyama, T; Takahashi, A; Tanida, N | 1 |
| Alabaster, O; Frost, A; Shivapurkar, N; Tang, ZC | 2 |
| Aizawa, R; Fukaura, Y; Hasebe, M; Ito, M; Morotomi, M; Narisawa, T | 1 |
| Mizuoka, H; Shikata, N; Tsubura, A; Yang, J | 1 |
| Farber, E | 1 |
| Hino, A; Itakura, M; Iwahana, H; Izumi, K; Kudo, E; Min, H; Yoshimoto, K | 1 |
| Kaeck, M; Lu, J; Pei, H; Thompson, HJ | 1 |
| Asamoto, M; Kim, DJ; Kim, JM; Murakoshi, M; Nir, Z; Nishino, H; Ota, T; Sekine, K; Takasuka, N; Tsuda, H | 1 |
| Fukaura, Y; Narisawa, T; Sekiguchi, H; Terada, K | 2 |
| Fukaura, Y; Hasebe, M; Inakuma, T; Ishiguro, Y; Narisawa, T; Nishino, H; Nomura, S; Oshima, S; Sakamoto, H; Takayasu, J | 1 |
| Brasic, GM; Gould, MN; Grubbs, CJ; Haag, JD; Kelloff, GJ; Lubet, RA; Newton, MA; Shepel, LA | 1 |
| Aquilina, G; Bignami, M; Crompton, NE; Jiricny, J; Lettieri, T; Marra, G; Palombo, F | 1 |
| Fukaura, Y; Inakuma, T; Narisawa, T; Nishino, H; Oshima, S; Yano, M | 1 |
| Fukushima, S; Morii, H; Nishizawa, Y; Otani, S; Salim, EI; Taniyama, T; Wanibuchi, H; Yano, Y | 1 |
| Fukaura, Y; Hasebe, M; Inakuma, T; Narisawa, T; Nomura, S; Oshima, S | 1 |
| Corpet, DE; Delverdier, M; Parnaud, G; Peiffer, G; Taché, S | 1 |
| Chen, B; Wang, G; Wang, P; Zhou, S | 2 |
| Chen, BQ; Wang, GJ; Zhou, SB; Zhu, Y | 1 |
| Khachik, F; Masuda, M; Murakoshi, M; Narisawa, T; Nishino, H; Okuda, M; Onozuka, M; Satomi, Y; Takasuka, N; Takayasu, J; Tokuda, H; Tsuruta, J; Yamaguchi, S; Yano, M | 1 |
| Fukaura, Y; Nakai, K; Narisawa, T; Takeba, N | 1 |
| Bolognani, F; Pool-Zobel, BL; Rowland, IR; Rumney, CJ | 1 |
| Gonda, M; Hatakeyama, S; Hayashi, M; Kondo, K; Miyajima, H; Noguchi, T; Ohyama, W; Tokumitsu, T; Ueno, Y; Watabe, E; Yoshida, J | 1 |
| Herp, A; Lev, R | 1 |
| Kritchevsky, D; Reddy, BS; Watanabe, K; Weisburger, JH | 1 |
| Cohen, BI; Fazzini, E; Raicht, RF; Sarwal, AN; Takahashi, M | 1 |
| Dean, RJ; Feeser, D; Smith, JM; Sporn, MB; Ward, JM; Wenk, ML | 1 |
| Reddy, BS; Watanabe, K; Weisburger, JH; Wong, CQ | 1 |
| Schabel, FM | 1 |
| Balish, E; Bryan, GT; Croft, WA; Lower, G; Pamukcu, AM; Shih, CN; Yale, CE | 1 |
| Reddy, BS; Watanabe, K; Weisburger, JH | 1 |
| Carter, SK; Slavik, M; Wasserman, TH | 1 |
| Corbett, TH; Griswold, DP; Peckham, JC; Roberts, BJ; Schabel, FM | 1 |
| Maronpot, R; Narisawa, T; Reddy, BS; Weisburger, JH; Wynder, EL | 1 |
| Corbett, TH; Griswold, DP | 1 |
| Maronpot, RR; Narisawa, T; Weisburger, JH; Wong, CQ | 1 |
| Kawaura, A; Oda, M; Sawada, K; Shimoyama, T; Tanida, T | 1 |
| Asakawa, Y; Fukaura, Y; Kotanagi, H; Narisawa, T | 1 |
| Bilbin, M; Czeczot, H; Tudek, B | 1 |
| Fukaura, Y; Isoda, Y; Kotanagi, H; Kotsugai, M; Koyama, H; Kusaka, H; Narisawa, T; Nishizawa, Y; Takahashi, M; Yamazaki, Y | 1 |
| Alexander, RJ; Buxbaum, JN; Raicht, RF | 2 |
| Alexander, RJ; Buxbaum, JN; Garte, SJ; Raicht, RF | 1 |
| Alexander, RJ; Brasitus, TA; Jacoby, RF; Raicht, RF | 1 |
| Iwasaki, S; Masui, T; Shirai, T; Tamano, S; Yamamoto, A | 1 |
| Kano, M; Kawaura, A; Maekawa, S; Oda, M; Sawada, K; Shimoyama, T; Tanida, N | 1 |
| Kawaura, A; Maekawa, S; Oda, M; Sawada, K; Sawada, Y; Shimoyama, T; Takahashi, A; Tanida, N | 1 |
| Kawaura, A; Oda, M; Sawada, K; Shimoyama, T; Tanida, N | 1 |
| Fujiki, H; Fukaura, Y; Narisawa, T; Niwa, M; Takahashi, M | 1 |
| Bokkenheuser, VD; Cohen, BI; Matoba, N; McSherry, CK; Mosbach, EH; Scholes, J; Winter, J | 1 |
| Kawaura, A; Narisawa, T; Oda, M; Sawada, K; Shimoyama, T; Tanida, N | 1 |
| Broitman, SA | 1 |
| Kawaura, A; Narisawa, T; Sawada, K; Shimoyama, T; Tanida, N | 1 |
| Amberger, H | 1 |
| Aonuma, T | 1 |
| Grueva, D; Hadjiolov, D | 1 |
| Luckert, PH; Pollard, M | 1 |
| Goad, ME; Lindenschmidt, RC; Tryka, AF; Witschi, HP | 1 |
| Wang, CX; Watanabe, K; Weisburger, JH; Williams, GM | 1 |
4 review(s) available for methylnitrosourea and Cancer of Colon
| Article | Year |
|---|---|
Role of age in host sensitivity to carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Carcinogens; Colonic Neoplasms; DNA Repair; Female; Humans; Male; Methylnitrosourea; Neoplasms; Uterine Neoplasms; Vaginal Neoplasms | 1983 |
Nitrosoureas: a review of experimental antitumor activity.
Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Leukemia L1210; Lomustine; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Semustine | 1976 |
Clinical comparison of the nitrosoureas.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carmustine; Chemical Phenomena; Chemistry; Colonic Neoplasms; Drug Therapy, Combination; Hodgkin Disease; Humans; Lomustine; Lung Neoplasms; Lymphoma; Melanoma; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Rectal Neoplasms | 1975 |
Cholesterol conundrums: the relationship between dietary and serum cholesterol in colon cancer.
Topics: 1,2-Dimethylhydrazine; Adult; Animals; Azoxymethane; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Cocarcinogenesis; Colonic Neoplasms; Diagnosis-Related Groups; Dietary Fats; Dimethylhydrazines; Disease Models, Animal; Epidemiologic Methods; Humans; Methylnitronitrosoguanidine; Methylnitrosourea | 1986 |
97 other study(ies) available for methylnitrosourea and Cancer of Colon
| Article | Year |
|---|---|
Preventive potential of dietary inclusion of Brachystegia eurycoma (Harms) seeds on N-methyl-N-nitrosourea-induced colon carcinogenesis in Wistar rats.
Topics: Animals; Carcinoembryonic Antigen; Carcinogenesis; Catalase; Colon; Colonic Neoplasms; Dietary Fiber; Fabaceae; Flavonoids; Male; Malondialdehyde; Methylnitrosourea; MutL Protein Homolog 1; Polyphenols; Rats, Wistar; Seeds; Superoxide Dismutase | 2019 |
Mutation detection in the promoter region of survivin gene on N-methyl-N-nitrosourea induced colon tumor model in experiment.
Topics: Animals; Carcinogens; Colonic Neoplasms; Disease Models, Animal; Methylnitrosourea; Microtubule-Associated Proteins; Mutation; Promoter Regions, Genetic; Rats, Wistar; Survivin | 2014 |
Trypanosoma cruzi extracts elicit protective immune response against chemically induced colon and mammary cancers.
Topics: 1,2-Dimethylhydrazine; Animals; Antibodies, Protozoan; Antibody-Dependent Cell Cytotoxicity; Antigens, Protozoan; Breast Neoplasms; Cancer Vaccines; Carcinogens; Cell Line, Tumor; Colonic Neoplasms; Cross Reactions; Disease Models, Animal; Female; Flow Cytometry; Humans; Immunohistochemistry; Methylnitrosourea; Rats; Rats, Wistar; Trypanosoma cruzi | 2016 |
Chemopreventive effect of 4-[3,5-Bis(trimethylsilyl) benzamido] benzoic acid (TAC-101) on MNU-induced colon carcinogenesis in a rat model.
Topics: Adenocarcinoma; Alkylating Agents; Animals; Apoptosis; Benzoates; Cell Proliferation; Colonic Neoplasms; fas Receptor; Immunoenzyme Techniques; Male; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Trimethylsilyl Compounds | 2009 |
Chemopreventive efficacy of naproxen and nitric oxide-naproxen in rodent models of colon, urinary bladder, and mammary cancers.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Butylhydroxybutylnitrosamine; Carcinogens; Colonic Neoplasms; Diet; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Naproxen; Nitric Oxide Donors; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Urinary Bladder Neoplasms | 2009 |
Inhibition of methylnitrosourea (MNU) induced oxidative stress and carcinogenesis by orally administered bee honey and Nigella grains in Sprague Dawely rats.
Topics: Adenocarcinoma; Administration, Oral; Alkylating Agents; Animals; Colonic Neoplasms; Female; Honey; Malondialdehyde; Methylnitrosourea; Neoplasms, Experimental; Nigella sativa; Nitric Oxide; Oxidative Stress; Phytotherapy; Rats; Rats, Sprague-Dawley | 2002 |
Variable E-cadherin expression in a MNU-induced colon tumor model in rats which exposed with 50 Hz frequency sinusoidal magnetic field.
Topics: Animals; Cadherins; Colon; Colonic Neoplasms; Disease Models, Animal; Electromagnetic Fields; Immunoenzyme Techniques; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Wistar | 2002 |
A noncarcinogenic small dose of n-methylnitrosourea enhances colon tumorigenesis in F344 rats.
Topics: Administration, Rectal; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Female; Methylnitrosourea; Neoplasm Invasiveness; Rats; Rats, Inbred F344 | 2003 |
Prevention by intrarectal 5-aminosalicylic acid of N-methylnitrosourea-induced colon cancer in F344 rats.
Topics: Administration, Rectal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Transformation, Neoplastic; Colonic Neoplasms; Female; Mesalamine; Methylnitrosourea; Rats; Rats, Inbred F344 | 2003 |
Modulation of N-methyl-N-nitrosourea-induced crypt restricted metallothionein immunopositivity in mouse colon by a non-genotoxic diet-related chemical.
Topics: Alkylating Agents; Animals; Carrageenan; Colon; Colonic Neoplasms; Diet; DNA; DNA Adducts; Drug Combinations; Feces; Female; Metallothionein; Methylnitrosourea; Mice; Mice, Inbred BALB C; Stem Cells | 2004 |
Chemoprevention of chemically-induced mammary and colon carcinogenesis by 1alpha-hydroxyvitamin D5.
Topics: Animals; beta Catenin; Chemoprevention; Colonic Neoplasms; Diet; Female; Hydroxycholecalciferols; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Conformation; Organ Specificity; Rats; Rats, Sprague-Dawley; Wnt1 Protein | 2005 |
Tumor specific reactivity during development of N-methyl-N-nitrosourea-induced rat colon cancer.
Topics: Animals; Body Weight; Colonic Neoplasms; Lymphocyte Culture Test, Mixed; Male; Methylnitrosourea; Nitrosourea Compounds; Probability; Rats; Rats, Inbred Strains | 1983 |
Effect of BCG immunotherapy on N-nitroso-N-methylurea-induced carcinogenesis of guinea pig colon.
Topics: Animals; Colonic Neoplasms; Guinea Pigs; Immunotherapy; Methylnitrosourea; Mycobacterium bovis | 1984 |
Reduction of carcinogenicity of N-nitrosomethylurea by indomethacin and failure of resuming effect of prostaglandin E2 (PGE2) against indomethacin.
Topics: Animals; Colonic Neoplasms; Dinoprostone; Indomethacin; Male; Methylnitrosourea; Nitrosourea Compounds; Prostaglandins E; Rats; Rats, Inbred Strains | 1984 |
Inhibition of initiation and promotion by N-methylnitrosourea-induced colon carcinogenesis in rats by non-steroid anti-inflammatory agent indomethacin.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Female; Indomethacin; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred F344; Time Factors | 1983 |
Lack of effect of dietary fat on N-nitrosomethyl urea (NMU)-induced colon tumorigenesis in rats.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dietary Fats; Drug Interactions; Male; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Sarcoma, Experimental | 1984 |
Chemoprevention of development of colonic adenomatosis and carcinomatosis with 5-fluorouracil and ftorafur on animal model.
Topics: Adenoma; Animals; Carcinoma; Colon; Colonic Neoplasms; Female; Fluorouracil; Methylnitrosourea; Neoplasms, Experimental; Rats; Tegafur | 1980 |
Development of a carcinogen-induced rat colon cancer with lymph-node metastases.
Topics: Animals; Colonic Neoplasms; Injections; Lymphatic Metastasis; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Rectum | 1983 |
Effect of cholic acid feeding on N-methyl-N-nitrosourea-induced colon tumors and cell kinetics in rats.
Topics: Animals; Bile Acids and Salts; Cell Division; Cholic Acids; Cocarcinogenesis; Colon; Colonic Neoplasms; DNA; Kinetics; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Sterols | 1980 |
The kinetics of the protective effect of beta-sitosterol against MNU-induced colonic neoplasia.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Colonic Neoplasms; DNA; Kinetics; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Sitosterols | 1982 |
Inhibition of development of methylnitrosourea-induced rat colonic tumors by peroral administration of indomethacin.
Topics: Animals; Colonic Neoplasms; Female; Indomethacin; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 1982 |
Reduction of N-methyl-N-nitrosourea-induced colon tumors in the rat by cholesterol.
Topics: Animals; Cholesterol, Dietary; Colonic Neoplasms; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344 | 1982 |
Effect of dietary sodium ascorbate on 1,2-dimethylhydrazine- or methylnitrosourea-induced colon carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Ascorbic Acid; Colonic Neoplasms; Diet; Dimethylhydrazines; Female; Methylhydrazines; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats | 1982 |
Inhibition of development of methylnitrosourea-induced rat colon tumors by indomethacin treatment.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Female; Indomethacin; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats | 1981 |
Endoscopic diagnosis of chemically induced autochthonous colonic tumors in rats.
Topics: Adenocarcinoma; Animals; Carcinogens; Colon; Colonic Neoplasms; Colonoscopy; Dimethylnitrosamine; Evaluation Studies as Topic; Hyperplasia; Intestinal Polyps; Male; Methylamines; Methylnitronitrosoguanidine; Methylnitrosourea; Rats | 1981 |
Establishment and biological properties of a guinea pig colonic adenocarcinoma cell line induced by N-methyl-N-nitrosourea.
Topics: Adenocarcinoma; Aneuploidy; Animals; Cell Count; Cell Line; Chromosomes; Colonic Neoplasms; Desmosomes; Female; Guinea Pigs; Methylnitrosourea; Mice; Mice, Nude; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Time Factors | 1981 |
Effects of bile acids on colon carcinogenesis in rats treated with carcinogens.
Topics: Animals; Chenodeoxycholic Acid; Cholic Acids; Cocarcinogenesis; Colonic Neoplasms; Diet; Feces; Methods; Methylnitrosourea; Neoplasms, Experimental; Rats; Steroids | 1981 |
Effects of three retinoids on colon adenocarcinomas, sarcomas and hyperplastic polyps induced by intrarectal N-methyl-N-nitrosourea administration in male F344 rats.
Topics: Adenocarcinoma; Animals; Carcinogens; Colonic Neoplasms; Hyperplasia; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Sarcoma, Experimental; Suppositories; Vitamin A | 1981 |
Effect of retinoids on the induction of colon cancer in F344 rats by N-methyl-N-nitrosourea or by 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Drug Interactions; Endoscopy; Male; Methylhydrazines; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Time Factors; Vitamin A | 1981 |
Mouse colostomy model for studies on large bowel cancer.
Topics: Animals; Colonic Neoplasms; Colostomy; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Rectal Neoplasms; Transplantation, Isogeneic | 1980 |
Chemoprevention of development of colonic adenomatosis and carcinomatosis with intrarectal dose of 5-FU on animal model.
Topics: Adenoma; Animals; Colonic Neoplasms; Female; Fluorouracil; Injections, Intraperitoneal; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344; Rectum | 1980 |
Protective effect of plant sterols against chemically induced colon tumors in rats.
Topics: Animals; Bile Acids and Salts; Cholesterol; Colonic Neoplasms; Diet; Diet, Vegetarian; Feces; Humans; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Sitosterols | 1980 |
Endoscopic detection of experimentally induced colonic neoplasms in guinea pigs (Cavia porcellus).
Topics: Animals; Colonic Neoplasms; Colonoscopes; Colonoscopy; Female; Guinea Pigs; Male; Methylnitrosourea; Neoplasms, Experimental; Rodent Diseases | 1980 |
Chemoprevention of digestive organs carcinogenesis by natural product protocatechuic acid.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azoxymethane; Colonic Neoplasms; Diethylnitrosamine; Digestive System Neoplasms; Female; Humans; Hydroxybenzoates; In Vitro Techniques; Liver Neoplasms; Male; Methylnitrosourea; Mouth Neoplasms; Rats; Rats, Inbred F344 | 1995 |
Colon cancer prevention with a small amount of dietary perilla oil high in alpha-linolenic acid in an animal model.
Topics: alpha-Linolenic Acid; Animals; Body Weight; Cholesterol; Colon; Colonic Neoplasms; Dietary Fats; Disease Models, Animal; Eating; Fatty Acids; Female; Intestinal Mucosa; Linoleic Acids; Lipids; Methylnitrosourea; Phospholipids; Plant Oils; Rats; Rats, Inbred F344; Safflower Oil; Time Factors; Triglycerides | 1994 |
DNA adduct formation and assessment of aberrant crypt foci in vivo in the rat colon mucosa after treatment with N-methyl-N-nitrosourea.
Topics: Animals; Colon; Colonic Neoplasms; DNA; Dose-Response Relationship, Drug; Guanine; Intestinal Mucosa; Male; Methylnitrosourea; Rats; Rats, Inbred F344; Time Factors; Tritium | 1994 |
A very low dose of green tea polyphenols in drinking water prevents N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats.
Topics: Animals; Colonic Neoplasms; Drinking; Female; Flavonoids; Methylnitrosourea; Phenols; Polymers; Polyphenols; Rats; Rats, Inbred F344; Tea | 1993 |
Tumor promotion by fecapentaene-12 in a rat colon carcinogenesis model.
Topics: Animals; Carcinogens; Cocarcinogenesis; Colonic Neoplasms; Disease Models, Animal; Female; Intestinal Mucosa; Methylnitrosourea; Polyenes; Rats; Rats, Inbred F344 | 1993 |
Reduction of aberrant crypt foci induced in rat colon with azoxymethane or methylnitrosourea by feeding cholic acid.
Topics: Analysis of Variance; Animals; Azoxymethane; Body Weight; Cell Division; Cholic Acid; Cholic Acids; Colonic Neoplasms; Intestinal Mucosa; Male; Methylnitrosourea; Precancerous Conditions; Random Allocation; Rats; Rats, Sprague-Dawley | 1993 |
Sulphated bile acid per se inhibits colonic carcinogenesis in mice.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Adenoma; Administration, Oral; Administration, Rectal; Animals; Bile Acids and Salts; Carcinogens; Carcinoma, Squamous Cell; Cholic Acids; Colon; Colonic Neoplasms; Deoxycholic Acid; Dimethylhydrazines; Feces; Female; Germ-Free Life; Injections, Subcutaneous; Lithocholic Acid; Methylnitrosourea; Mice; Mice, Inbred ICR | 1993 |
A rapid dual organ rat carcinogenesis bioassay for evaluating the chemoprevention of breast and colon cancer.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Breast Neoplasms; Carcinogenicity Tests; Carcinogens; Cocarcinogenesis; Colonic Neoplasms; Dietary Fats; Dietary Fiber; Drug Screening Assays, Antitumor; Evaluation Studies as Topic; Female; Methylnitrosourea; Phytic Acid; Rats; Rats, Sprague-Dawley | 1996 |
The effect of dietary fat on the promotion of mammary and colon cancer in a dual-organ rat carcinogenesis model.
Topics: Adenocarcinoma; Adenoma; Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Bile Acids and Salts; Body Weight; Cholesterol; Colonic Neoplasms; Drinking; Eating; Enzyme Inhibitors; Feces; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Methylnitrosourea; Pravastatin; Rats; Rats, Inbred F344; Sterols | 1996 |
Colon carcinogenesis in shrews by intrarectal infusion of N-methyl-N-nitrosourea.
Topics: Administration, Rectal; Animals; Carcinogens; Colonic Neoplasms; Drug Administration Schedule; Female; Methylnitrosourea; Neoplasms, Experimental; Shrews | 1996 |
Monoclonal and polyclonal development of digestive tract tumors in chimeric mice.
Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Carrier Proteins; Chimera; Colonic Neoplasms; Diethylnitrosamine; Digestive System Neoplasms; Dimethylhydrazines; HSP70 Heat-Shock Proteins; Immunohistochemistry; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Proteins; Precancerous Conditions; Stomach Neoplasms | 1997 |
p53 gene mutation in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder tumors and N-methyl-N-nitrosourea-induced colon tumors of rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Colonic Neoplasms; Exons; Genes, p53; Male; Methylnitrosourea; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1997 |
Gene expression changes associated with chemically induced rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Cloning, Molecular; Colonic Neoplasms; DNA, Neoplasm; Female; Gene Expression; Genetic Markers; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Homology, Amino Acid | 1997 |
Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEN, MNU and DMH.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carotenoids; Chemoprevention; Colonic Neoplasms; Diethylnitrosamine; Female; Liver Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Lycopene; Male; Methylnitrosourea; Mice; Organ Size | 1997 |
Prevention of N-methylnitrosourea-induced colon tumorigenesis by ursodeoxycholic acid in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Time Factors; Ursodeoxycholic Acid | 1998 |
Prevention of N-methylnitrosourea-induced colon carcinogenesis in F344 rats by lycopene and tomato juice rich in lycopene.
Topics: Animals; Anticarcinogenic Agents; Beverages; Carcinogens; Carotenoids; Colonic Neoplasms; Female; Lycopene; Methylnitrosourea; Nutritive Value; Rats; Rats, Inbred F344; Solanum lycopersicum | 1998 |
A comparative analysis of allelic imbalance events in chemically induced rat mammary, colon, and bladder tumors.
Topics: Alleles; Animals; Azoxymethane; Butylhydroxybutylnitrosamine; Carcinogens; Chromosome Mapping; Codon; Colonic Neoplasms; Female; Genes, ras; Genetic Markers; Humans; Loss of Heterozygosity; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Microsatellite Repeats; Point Mutation; Rats; Rats, Inbred F344; Rats, Inbred WF; Urinary Bladder Neoplasms | 1999 |
Effect of hMSH6 cDNA expression on the phenotype of mismatch repair-deficient colon cancer cell line HCT15.
Topics: Base Pair Mismatch; Base Sequence; Colonic Neoplasms; DNA Primers; DNA Repair; DNA-Binding Proteins; DNA, Complementary; G2 Phase; Guanine; Humans; Methylnitronitrosoguanidine; Methylnitrosourea; Microsatellite Repeats; Mutation; Phenotype; Transfection; Tumor Cells, Cultured | 1999 |
Inhibitory effects of ursodeoxycholic acid on N-methylnitrosourea-induced colon carcinogenesis and colonic mucosal telomerase activity in F344 rats.
Topics: Animals; Antineoplastic Agents; Carcinogens; Colon; Colonic Neoplasms; Enzyme Inhibitors; Female; Gastrointestinal Agents; Intestinal Mucosa; Methylnitrosourea; Rats; Rats, Inbred F344; Telomerase; Ursodeoxycholic Acid | 1999 |
Chemoprevention by the oxygenated carotenoid beta-cryptoxanthin of N-methylnitrosourea-induced colon carcinogenesis in F344 rats.
Topics: Animals; Anticarcinogenic Agents; beta Carotene; Colonic Neoplasms; Cryptoxanthins; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Xanthophylls | 1999 |
Chemopreventive effect of 24R,25-dihydroxyvitamin D(3) in N, N'-dimethylhydrazine-induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; 24,25-Dihydroxyvitamin D 3; Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Colonic Neoplasms; Diet; Diethylnitrosamine; Intestinal Mucosa; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344 | 2000 |
Prevention of N-methylnitrosourea-induced colon carcinogenesis in rats by oxygenated carotenoid capsanthin and capsanthin-rich paprika juice.
Topics: Animals; Antioxidants; Capsicum; Carcinogens; Carotenoids; Colon; Colonic Neoplasms; Female; Methylnitrosourea; Oxygen; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred F344; Xanthophylls | 2000 |
Consistent and fast inhibition of colon carcinogenesis by polyethylene glycol in mice and rats given various carcinogens.
Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Dietary Fats; Dose-Response Relationship, Drug; Female; Male; Methylnitrosourea; Mice; Polyethylene Glycols; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Time Factors | 2000 |
Effect of dietary fatty acids on tumorigenesis of colon cancer induced by methyl nitrosourea in rats.
Topics: Alkaline Phosphatase; Animals; Body Weight; Cell Cycle; Cell Transformation, Neoplastic; Colonic Neoplasms; Diet; Dietary Fats; Dinoprostone; Fatty Acids; Intestinal Mucosa; Male; Membrane Fluidity; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Testis | 2000 |
Effect of dietary fatty acids on colon tumorigenesis induced by methyl nitrosourea in rats.
Topics: Alkylating Agents; Animals; Cell Division; Cell Transformation, Neoplastic; Colonic Neoplasms; Dietary Fats; Disease Models, Animal; Fatty Acids; Fish Oils; Infusions, Parenteral; Male; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 2000 |
Cancer prevention by natural carotenoids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; beta Carotene; Carotenoids; Colonic Neoplasms; Cryptoxanthins; Disease Models, Animal; Fruit; Humans; Lutein; Lycopene; Methylnitrosourea; Mice; Rats; Rats, Inbred F344; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vegetables; Xanthophylls; Zeaxanthins | 2000 |
Chemoprevention of N-methylnitrosourea-induced colon carcinogenesis by ursodeoxycholic acid-5-aminosalicylic acid conjugate in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Bile Acids and Salts; Colonic Neoplasms; Female; Mesalamine; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Inbred F344; Ursodeoxycholic Acid | 2002 |
Effect of lactobacilli, bifidobacteria and inulin on the formation of aberrant crypt foci in rats.
Topics: 1,2-Dimethylhydrazine; Animals; Bifidobacterium; Carcinogens; Colonic Neoplasms; Dietary Fats; Inulin; Lactobacillus; Male; Methylnitrosourea; Precancerous Conditions; Probiotics; Rats; Rats, Sprague-Dawley | 2001 |
[Research on the mechanism of the fatty acid composition on the tumorigenic danger induced by chemical tumorigenic material].
Topics: Animals; Colonic Neoplasms; Dinoprostone; Fatty Acids; Intestinal Mucosa; Male; Membrane Fluidity; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 1999 |
Collaborative validation study of the in vivo micronucleus test using mouse colonic epithelial cells.
Topics: 1,2-Dimethylhydrazine; Animals; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Epithelial Cells; Male; Methylnitrosourea; Mice; Mice, Inbred ICR; Micronucleus Tests; Mitomycin; Mutagens | 2002 |
Pathogenesis of rat colon carcinomas induced by N-methyl-N-nitrosourea.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Female; Humans; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Species Specificity | 1978 |
Effect of dietary alfalfa, pectin, and wheat bran on azoxymethane-or methylnitrosourea-induced colon carcinogenesis in F344 rats.
Topics: Animals; Azoxymethane; Cellulose; Colonic Neoplasms; Dietary Fiber; Female; Medicago sativa; Methylnitrosourea; Neoplasms, Experimental; Pectins; Rats; Rats, Inbred F344; Triticum | 1979 |
Effects of dietary administration of chenodeoxycholic acid on N-methyl-N-nitrosourea-induced colon cancer in rats.
Topics: Animals; Chenodeoxycholic Acid; Colonic Neoplasms; Feces; In Vitro Techniques; Male; Methylnitrosourea; Rats; Sterols | 1979 |
Dose response to intrarectal administration of N-methyl-N-nitrosourea and histopathologic evaluation of the effect of two retinoids on colon lesions induced in rats.
Topics: Adenocarcinoma; Administration, Oral; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Injections; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rectum; Tretinoin; Vitamin A | 1978 |
Effect of dietary undegraded carrageenan on colon carcinogenesis in F344 rats treated with azoxymethane or methylnitrosourea.
Topics: Animals; Azo Compounds; Azoxymethane; Carrageenan; Cellulose; Colonic Neoplasms; Dietary Fiber; Female; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rectal Neoplasms | 1978 |
Effect of age, sex, and intestinal flora on the induction of colon tumors in rats.
Topics: Adenocarcinoma; Age Factors; Animals; Colonic Neoplasms; Drug Administration Schedule; Female; Germ-Free Life; Intestines; Male; Methylnitronitrosoguanidine; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Sex Factors; Time Factors; Transplantation, Homologous | 1977 |
Effect of high-fat diet on colon carcinogenesis in F344 rats treated with 1,2-dimethylhydrazine, methylazoxymethanol acetate, or methylnitrosourea.
Topics: Adenocarcinoma; Adenoma; Animals; Azo Compounds; Cattle; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Male; Meat; Methylazoxymethanol Acetate; Methylhydrazines; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344 | 1977 |
Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure.
Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma; Chemical Phenomena; Chemistry; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosomethylurethane; Transplantation, Homologous | 1975 |
Animal models for the study of dietary factors and cancer of the large bowel.
Topics: Animals; Colonic Neoplasms; Dietary Fats; Dimethylhydrazines; Disease Models, Animal; Guinea Pigs; Intestines; Lithocholic Acid; Methylnitrosourea; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Rats; Taurocholic Acid; Vitamin A Deficiency | 1975 |
A colon tumor model for anticancer agent evaluation.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Dimethylhydrazines; Disease Models, Animal; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosomethylurethane; Transplantation, Homologous | 1975 |
Large bowel carcinogenesis in mice and rats by several intrarectal doses of methylnitrosourea and negative effect of nitrite plus methylurea.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Squamous Cell; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Intestinal Neoplasms; Intestine, Large; Lung Neoplasms; Lymphoma; Male; Methylnitrosourea; Mice; Nitrites; Nitrosourea Compounds; Rectal Neoplasms; Thymus Neoplasms; Urea | 1976 |
Suppression of colonic carcinogenesis by vitamin D in rats.
Topics: Animals; Colonic Neoplasms; Disease Models, Animal; Female; Hydroxycholecalciferols; Lithocholic Acid; Methylnitrosourea; Rats; Rats, Inbred F344; Vitamin D | 1992 |
Inhibitory effect of cryptoporic acid E, a product from fungus Cryptoporus volvatus, on colon carcinogenesis induced with N-methyl-N-nitrosourea in rats and with 1,2-dimethylhydrazine in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Carcinogens; Colon; Colonic Neoplasms; Deoxycholic Acid; Dimethylhydrazines; Enzyme Induction; Feeding Behavior; Female; Intestinal Mucosa; Methylnitrosourea; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Polyporaceae; Rats; Rats, Inbred F344; Sesquiterpenes; Weight Gain | 1992 |
Induction of aberrant crypts in the colons of rats by alkylating agents.
Topics: 1,2-Dimethylhydrazine; Aging; Alkylating Agents; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Female; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Wistar | 1992 |
Inhibitory effect of dietary perilla oil rich in the n-3 polyunsaturated fatty acid alpha-linolenic acid on colon carcinogenesis in rats.
Topics: alpha-Linolenic Acid; Animals; Body Weight; Colonic Neoplasms; Dietary Fats; Dinoprostone; Fatty Acids; Feeding Behavior; Intestinal Mucosa; Linolenic Acids; Methylnitrosourea; Oils; Ornithine Decarboxylase; Rats; Rats, Inbred F344; Safflower Oil | 1991 |
Oncogene alterations in rat colon tumors induced by N-methyl-N-nitrosourea.
Topics: Animals; Blotting, Southern; Colonic Neoplasms; DNA; DNA, Neoplasm; Genes, abl; Genes, fos; Genes, myc; Genes, ras; Male; Methylnitrosourea; Oncogenes; Rats; Rats, Inbred F344 | 1992 |
Detection of transforming oncogenes in rat colon tumors induced by direct perfusion with N-methyl-N-nitrosourea.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Colonic Neoplasms; Genes, ras; Male; Methylnitrosourea; Mice; Mice, Nude; Oncogenes; Perfusion; Rats; Rats, Inbred F344 | 1992 |
K-ras oncogene mutations in rat colon tumors induced by N-methyl-N-nitrosourea.
Topics: 3T3 Cells; Animals; Colonic Neoplasms; DNA, Neoplasm; Gene Expression Regulation; Genes, ras; Male; Methylnitrosourea; Mice; Mutation; Rats; Rats, Inbred F344 | 1992 |
Induction of invasive carcinomas of the seminal vesicles and coagulating glands of F344 rats by administration of N-methylnitrosourea or N-nitrosobis(2-oxopropyl)amine and followed by testosterone propionate with or without high-fat diet.
Topics: Animals; Body Weight; Bulbourethral Glands; Colonic Neoplasms; Dietary Fats; Drug Synergism; Genital Neoplasms, Male; Kidney Neoplasms; Lung Neoplasms; Male; Methylnitrosourea; Nitrosamines; Organ Size; Prostate; Prostatic Neoplasms; Radioimmunoassay; Rats; Rats, Inbred F344; Seminal Vesicles; Testosterone; Urethral Neoplasms; Urinary Bladder Neoplasms | 1991 |
Enhanced expression of oncogene-encoded mRNA in a rat model of colon cancer.
Topics: Adenoma; Animals; Carcinogens; Carcinoma; Cholic Acid; Cholic Acids; Colon; Colonic Neoplasms; Gene Expression; Male; Methylnitrosourea; Rats; Rats, Inbred F344; RNA, Messenger | 1991 |
Effects of 1 alpha-hydroxyvitamin D3 on N-methyl-N-nitrosourea-induced colonic tumorigenesis, and on fecal bile acid profiles with respect to soluble and precipitated phases in rats.
Topics: Animals; Bile Acids and Salts; Calcium; Colonic Neoplasms; Feces; Female; Hydroxycholecalciferols; Methylnitrosourea; Rats; Rats, Inbred F344 | 1990 |
1 Alpha-hydroxyvitamin D3 suppresses colonic tumorigenesis induced by repetitive intrarectal injection of N-methyl-N-nitrosourea in rats.
Topics: Adenoma; Administration, Rectal; Animals; Body Weight; Colonic Neoplasms; Female; Hydroxycholecalciferols; Incidence; Methylnitrosourea; Rats; Rats, Inbred F344 | 1990 |
Supplemental administration of 1 alpha-hydroxyvitamin D3 inhibits promotion by intrarectal instillation of lithocholic acid in N-methyl-N-nitrosourea-induced colonic tumorigenesis in rats.
Topics: Animals; Colonic Neoplasms; Female; Hydroxycholecalciferols; Lithocholic Acid; Methylnitrosourea; Rats; Rats, Inbred F344; Rectum | 1989 |
Inhibition of methylnitrosourea-induced large bowel cancer development in rats by sarcophytol A, a product from a marine soft coral Sarcophyton glaucum.
Topics: Animals; Antineoplastic Agents; Body Weight; Colonic Neoplasms; Diterpenes; Female; Methylnitrosourea; Mollusca; Rats; Rats, Inbred F344; Reference Values | 1989 |
Effects of calcium and bile acid feeding on colon tumors in the rat.
Topics: Adenocarcinoma; Adenoma; Animals; Calcium, Dietary; Carcinoma in Situ; Cholic Acid; Cholic Acids; Colonic Neoplasms; Male; Methylnitrosourea; Neoplasm Invasiveness; Rats; Rats, Inbred F344; Reference Values | 1989 |
Effects of oral administration of sulfolithocholic acid disodium salt and lithocholic acid sodium salt on N-methyl-N-nitrosourea-induced colonic tumorigenesis in conventional rats.
Topics: Administration, Oral; Animals; Colonic Neoplasms; Feces; Female; Lithocholic Acid; Methylnitrosourea; Rats; Rats, Inbred F344 | 1989 |
Promoting effect of 5 beta-chol-3-en-24-oic acid on N-methyl-N-nitrosourea-induced colonic tumorigenesis in rats.
Topics: Animals; Bile Acids and Salts; Body Weight; Carcinogens; Cholic Acids; Colon; Colonic Neoplasms; Feces; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Time Factors | 1987 |
Different autochthonous models of colorectal cancer in the rat.
Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Animals; Colonic Neoplasms; Dimethylhydrazines; Dimethylnitrosamine; Disease Models, Animal; Methylnitronitrosoguanidine; Methylnitrosourea; Rats; Rectal Neoplasms | 1986 |
[Histopathologic study of rapidly induced colonic carcinoma in rats by N-methyl-N-nitrosourea--with special reference to histogenesis].
Topics: Animals; Carcinoma; Colonic Neoplasms; DNA, Neoplasm; Intestinal Mucosa; Male; Methylnitrosourea; Neoplasm Invasiveness; Rats | 1986 |
Effect of combined tigason and selenium treatment on colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dimethylhydrazines; Etretinate; Male; Methylnitrosourea; Rats; Selenium | 1986 |
Tumorigenic effects of direct- and indirect-acting chemical carcinogens in rats on a restricted diet.
Topics: Animals; Body Weight; Colonic Neoplasms; Diet; Intestinal Neoplasms; Intestine, Large; Intestine, Small; Male; Methylazoxymethanol Acetate; Methylnitrosourea; Rats; Rats, Inbred Strains | 1985 |
The effects of dietary butylated hydroxytoluene on liver and colon tumor development in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Butylated Hydroxytoluene; Carcinogens; Colonic Neoplasms; Diet; Dimethylhydrazines; Female; Gastrointestinal Neoplasms; Liver Neoplasms; Male; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Multiple Primary; Time Factors | 1986 |
Induction of colon cancer in inbred Syrian hamsters by intrarectal administration of benzo[alpha]pyrene, 3-methylcholanthrene and N-methyl-N-nitrosourea.
Topics: Animals; Benzo(a)pyrene; Colonic Neoplasms; Cricetinae; Male; Mesocricetus; Methylcholanthrene; Methylnitrosourea; Rectum | 1985 |