Page last updated: 2024-08-21

methylnitrosourea and Breast Cancer

methylnitrosourea has been researched along with Breast Cancer in 90 studies

Research

Studies (90)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (18.89)	18.7374
1990's	14 (15.56)	18.2507
2000's	29 (32.22)	29.6817
2010's	27 (30.00)	24.3611
2020's	3 (3.33)	2.80

Authors

Authors	Studies
Carvalho Dartora, VFM; Costa, SKP; Fantini, MCA; Lopes, LB; Machado-Neto, JA; Malagó, ID; Marçal Pessoa, AF; Salata, GC	1
Daino, K; Imaoka, T; Kakinuma, S; Kokubo, T; Nishimura, M; Nishimura, Y; Shimada, Y; Takabatake, M	1
Alnaseer, SM; Gourishetti, K; Hussain, SM; Kishore, A; Nandakumar, K; Nayak, PG; Ramalingayya, GV; Rao, CM	1
Chang, CH; Hsu, LS; Lee, YJ; Wang, CJ	1
Kaithwas, G; Kumar, D; Rawat, A; Roy, S; Singh, M	1
Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Morozov, DV; Poveshchenko, AF; Raiter, TV; Strunkin, DN	1
Karia, P; Patel, KV; Rathod, SSP	1
Anderson, SM; Edwards, DP; Giles, ED; Jindal, S; MacLean, PS; Schedin, P; Schedin, T; Thor, AD; Wellberg, EA	1
Bolzan, AD; Cocca, C; Lasagna, M; Monczor, F; Núñez, M; Pavicic, W; Richard, S; Ventura, C; Zappia, CD	1
Cheng, D; Du, J; Han, B; Li, J; Peng, X; Yu, X; Zhu, Y	1
Bai, X; Chen, Z; Dai, Y; Gao, Q; Gao, T; Jia, C; Lai, P; Lin, J; Ren, Z; Song, Q; Wan, Z; Wang, Y; Zhang, Y; Zhao, A; Zhao, Z; Zheng, H; Zhou, X	1
Cho, K; Choi, WS; Crane, CL; Park, CS	1
Brauer, HA; D'Arcy, M; Hamajima, N; Lampe, PD; Li, CI; Libby, TE; Thompson, HJ; Troester, MA; Yasui, YY	1
El Ashry, el S; Malki, A	1
Bai, Q; Chang, H; Mi, M; Peng, X; Yu, X; Zhang, Q; Zhou, Y; Zhu, J	1
Bojková, B; Ekmekcioglu, C; Fedoročko, P; Jäger, W; Jendželovský, R; Kajo, K; Kassayová, M; Kisková, T; Kokošová, N; Kubatka, P; Maier-Salamon, A; Mikeš, J; Orendáš, P; Papčová, Z; Rentsen, E; Svoboda, M; Thalhammer, T	1
Abroun, S; Ashrafi, M; Azizian, M; Bathaie, SZ	1
Berriel, E; Bollati-Fogolín, M; Chiale, C; Chiribao, ML; Festari, MF; Freire, T; Mazal, D; Medeiros, A; Osinaga, E; Rabinovich, GA; Robello, C; Rondán, M; Ubillos, L	1
Blanc, C; Bougnoux, P; Chauvin, L; Chevalier, S; Domingo, I; Goupille, C; Guimaraes, C; Mahéo, K; Pinault, M	1
Deng, Y; Graidist, P; Hiransai, P; Sriwiriyajan, S; Tedasen, A	1
Cespedes Feliciano, E; De Jonghe, BC; Joshi, A; Leonard, JJ; Liu, Y; Malik, VS; Rosner, B; Schweitzer, A; Sturgeon, KM; Tobias, DK	1
Beumer, JH; Christner, SM; Davidson, NE; Hahm, ER; Kim, SH; Pore, SK; Roy, R; Samanta, SK; Sehrawat, A; Shuai, Y; Singh, KB; Singh, SV	1
Alvarez de Cienfuegos, G; Carrera, MP; De Pablo, MA; Martinez-Martos, JM; Puertollano, E; Puertollano, MA; Ramirez-Expósito, MJ	1
Zarbl, H; Zhang, X	1
Andrianakos, AG; Fleming-Elder, BK; Giles, ED; Gilman, KA; Jackman, MR; Johnson, GC; MacLean, PS; McDaniel, SM; Schedin, PJ; Shroyer, KR	1
McGinley, JN; Stushnoff, C; Thompson, HJ; Thompson, MD	1
Brtko, J; Macejová, D; Ondková, S	1
Benalcazar, WA; Boppart, SA; Chaney, EJ; Chowdary, PD; Gruebele, M; Jiang, Z; Marks, DL	1
Gould, MN; Haag, JD; Mau, B; Samuelson, DJ; Sharma, D; Smits, BM; Woditschka, S	1
Brown, RJ; Gabrielson, E; Huso, DL; Jacobs, LK; Jeter, S; Khouri, NF; Kominsky, SL; Lange, JR; Mori, T; Powers, P; Rudek, MA; Stearns, V; Sukumar, S; Tarpinian, K; Tsangaris, TN; Yoshida, T; Zhang, Z	1
Berger, MR; Dineva, IK; Eibl, H; Konstantinov, SM; Zaharieva, MM	1
Jaafar, H; Murtey, MD; Sharif, SE	1
Aras, U; Gandhi, YA; Masso-Welch, PA; Morris, ME	1
Jiang, W; McGinley, JN; Thompson, HJ; Zhu, Z	1
Carrera, MP; García, MJ; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ; Valenzuela, MT	1
Bohlmann, R; Gieschen, H; Heinrich, N; Hoffmann, J; Hofmeister, H; Kroll, J; Künzer, H; Lichtner, RB; Nishino, Y; Parczyk, K; Sauer, G; Schneider, MR; Ulbrich, HF	1
Singh, M; Thompson, HJ	1
Baranová, M; Brtko, J; Macejová, D; Mostböck, S; Scheiblhofer, S; Thalhamer, J; Weiss, R	1
Caldwell, D; Kelley, MR; Rinne, M	1
Arias de Saavedra, JM; Carrera, Mdel P; García, MJ; Martínez-Martos, JM; Mayas, MD; Pérez, Mdel C; Ramírez-Expósito, MJ; Sánchez, R; Valenzuela, MT	1
Chan, MM; Iglehart, JD; Lu, X; Merchant, FM; Miron, PL	1
Badger, TM; Chatman, L; Eason, RR; Geng, Y; Korourian, S; Simmen, RC; Till, SR; Velarde, MC	1
Gulati, A; Rai, A; Rajeshkumar, NV; Shord, S	1
Anegon, I; Asghar, K; Ashgar, K; Boczkowski, J; Brion, R; Chauveau, C; Doebis, C; Hill, M; Kotsch, K; Mashreghi, MF; Mazal, D; Moffett, J; Osinaga, E; Pereira, V; Remy, S; Seifert, M; Tesson, L; Ubillos, L; Zagani, R	1
Christov, K; Green, A; Lubet, R; Punj, V; Shilkaitis, A; Steele, V	1
Bradbury, J	1
Goss, PE; Hu, H; Qi, S; Strasser-Weippl, K	1
Akinaga, S; Anazawa, H; Ishida, H; Kuwabara, T; Li, PK; Murakata, C; Nakata, T; Sato, N; Shiotsu, Y; Suzuki, M; Takebayashi, M; Tanaka, H; Terasaki, Y	1
Durando, M; Kass, L; Luque, EH; Muñoz-de-Toro, M; Piva, J; Sonnenschein, C; Soto, AM	1
Asamoto, M; Hokaiwado, N; Naiki-Ito, A; Ogawa, K; Shirai, T; Takahashi, S; Tsuda, H; Yamashita, H	1
Agarwal, A; Andersen, TT; Bennett, JA; Jacobson, HI; Lemanski, N; Narendran, A	1
Faiferman, I; Ghosh, BC; Ghosh, L; Nassauer, J	1
Irigoyen, ML; Nardi, J; Sarría, JA; Sosa, R	1
D'iachkovskaia, RF; Korman, DB; Krutova, TV; Shamaev, VI	1
Downing, M; Kieffer, JD; Maloof, F; Mover, H; Ridgway, EC; Vickery, AL	1
Kidwell, WR; Lewko, WM; Liotta, LA; Vonderhaar, BK; Wicha, MS	1
Arafah, BM; Finegan, HM; Manni, A; Pearson, OH; Roe, J	1
Kolarić, K; Roth, A	1
Dietrich, W; Görlich, M	1
Anzano, MA; Brown, CC; Byers, SW; Mullen, LT; Peer, CW; Roberts, AB; Smith, JM; Sporn, MB	1
Anzano, MA; Driver, CL; Letterio, JJ; Logsdon, DL; Mullen, LT; Peer, CW; Shrader, MW; Smith, JM; Uskoković, MR; Welsh, MC	1
Thompson, HJ	1
Alabaster, O; Frost, A; Shivapurkar, N; Tang, ZC	1
Chander, SK; Coombes, RC; Evans, TR; Luqmani, YA; Rowlands, MG	1
Gant, TW; Riley, J; Zhang, F	1
Chen, X; Guzman, RC; Nandi, S; Rajkumar, L; Thordarson, G; Yang, J	1
Bougnoux, P; Chajès, V; Cognault, S; Germain, E; Jourdan, ML; Lavillonnière, F; Lhuillery, C	1
Hejaz, HA; MacCarthy-Morrogh, L; Packham, G; Potter, BV; Purohit, A; Reed, MJ; Walden, L	1
Dagar, S; Onyüksel, H; Rubinstein, I; Sekosan, M	1
Dagar, S; Lee, BS; Onyüksel, H; Rubinstein, I; Sekosan, M	1
Conneely, OM; Gay, J; Hilsenbeck, SG; Medina, D; O'Malley, BW; Sivaraman, L; Zhong, L	1
Conneely, O; Ginger, M; Hilsenbeck, SG; Medina, D; Omalle, BW; Rosen, J; Sivaraman, L	1
Aldaz, CM; Ballenger, J; Davis, MF; El-Bayoumy, K; Li, JJ; Li, SA; Papa, D; Tawfik, O; Weroha, SJ	1
Anderson, MB; Bischoff, ED; Cheng, Q; Dai, J; Dwived, PD; Hill, SM; Kiefer, TL; Lai, L; Melancon, K; Moro, K; Nowfar, S; Teplitzky, SR; Yuan, L	1
Swanson, SM; Unterman, TG	1
Becci, PJ; Strum, JM	1
Kolarić, K	1
Lokich, JJ; Skarin, AT	1
Carter, SK; Slavik, M; Wasserman, TH	1
Bevilacqua, G; Liotta, LA; Sobel, ME; Steeg, PS	1
Berger, MR; Reinhardt, M; Schmähl, D; Yanapirut, P	1
Chander, SK; Coombes, RC; Dowsett, M; Jarman, M; Luqmani, Y; McCague, R; Newton, C	1
Basu, A; Modak, MJ; Osborne, MP; Telang, NT	1
Badger, B; Bartholomew, M; Demers, L; Herlyn, M; Manni, A; Masui, H; Mendelsohn, J; Wright, C	1
Berger, MR; Kaufmann, M; Petru, E; Zeller, WJ	2
Berger, U; Colston, KW; Coombes, RC	1
Barbacid, M; Carney, WP; Sukumar, S	1
Coombes, RC; Easton, D; Goss, PE; Singh, D; Wilkinson, JR; Williams, JC	1
Berger, M; Prekajac, J; von Angerer, E	1

Reviews

6 review(s) available for methylnitrosourea and Breast Cancer

Article	Year
Rat models of premalignant breast disease. Journal of mammary gland biology and neoplasia, 2000, Volume: 5, Issue:4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Disease Models, Animal; Mammary Neoplasms, Animal; Methylnitrosourea; Precancerous Conditions; Rats	2000
Effect of exercise intensity and duration on the induction of mammary carcinogenesis. Cancer research, 1994, Apr-01, Volume: 54, Issue:7 Suppl Topics: Animals; Breast Neoplasms; Exercise; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms; Physical Conditioning, Animal; Rats; Risk Factors	1994
Intrinsic multidrug class 1 and 2 gene expression and localization in rat and human mammary tumors. Laboratory investigation; a journal of technical methods and pathology, 1996, Volume: 75, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Breast Neoplasms; Drug Resistance, Multiple; Female; Gene Expression; Humans; Immunologic Techniques; In Situ Hybridization; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Oligonucleotide Probes; Rats; RNA, Messenger; Staining and Labeling	1996
Mechanisms of hormonal prevention of breast cancer. Annals of the New York Academy of Sciences, 2001, Volume: 952 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Breast Neoplasms; Cell Division; DNA Damage; Estradiol; Estrogens; Female; Gene Expression Profiling; Genes, p53; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Hormone-Dependent; Pregnancy; Progesterone; Rats; Rats, Inbred WF; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Reproductive History; Risk Factors	2001
Clinical comparison of the nitrosoureas. Cancer, 1975, Volume: 36, Issue:4 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carmustine; Chemical Phenomena; Chemistry; Colonic Neoplasms; Drug Therapy, Combination; Hodgkin Disease; Humans; Lomustine; Lung Neoplasms; Lymphoma; Melanoma; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Rectal Neoplasms	1975
Identification and characterization of differentially expressed genes in tumor metastasis: the nm23 gene. Basic life sciences, 1991, Volume: 57 Topics: Animals; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Line, Transformed; Cell Transformation, Viral; DNA; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Melanoma, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Metastasis; Rats; Transfection; Tumor Cells, Cultured	1991

Trials

2 trial(s) available for methylnitrosourea and Breast Cancer

Article	Year
Preclinical and clinical evaluation of intraductally administered agents in early breast cancer. Science translational medicine, 2011, Oct-26, Volume: 3, Issue:106 Topics: Adult; Animals; Antineoplastic Agents; Breast Neoplasms; Carboplatin; Doxorubicin; Drug Administration Routes; Female; Fluorouracil; Humans; Mammary Glands, Animal; Mammary Neoplasms, Animal; Methylnitrosourea; Paclitaxel; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Young Adult	2011
Nitrosourea combination chemotherapy: 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (methyl-CCNU) and cyclophosphamide. Oncology, 1975, Volume: 32, Issue:3-4 Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methylnitrosourea; Middle Aged; Neoplasms; Nitrosourea Compounds; Stomach Neoplasms	1975

Article

Year

Preclinical and clinical evaluation of intraductally administered agents in early breast cancer.

Science translational medicine, 2011, Oct-26, Volume: 3, Issue:106

Topics: Adult; Animals; Antineoplastic Agents; Breast Neoplasms; Carboplatin; Doxorubicin; Drug Administration Routes; Female; Fluorouracil; Humans; Mammary Glands, Animal; Mammary Neoplasms, Animal; Methylnitrosourea; Paclitaxel; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Young Adult

2011

Nitrosourea combination chemotherapy: 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (methyl-CCNU) and cyclophosphamide.

Oncology, 1975, Volume: 32, Issue:3-4

Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methylnitrosourea; Middle Aged; Neoplasms; Nitrosourea Compounds; Stomach Neoplasms

1975

Other Studies

82 other study(ies) available for methylnitrosourea and Breast Cancer

Article	Year
Microemulsion for Prolonged Release of Fenretinide in the Mammary Tissue and Prevention of Breast Cancer Development. Molecular pharmaceutics, 2021, 09-06, Volume: 18, Issue:9 Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cell Survival; Delayed-Action Preparations; Drug Liberation; Drug Screening Assays, Antitumor; Emulsions; Female; Fenretinide; Humans; Inhibitory Concentration 50; Mammary Glands, Animal; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Mice; Rats	2021
Copenhagen Rats Display Dominantly Inherited Yet Non-uniform Resistance to Spontaneous, Radiation-induced, and Chemically-induced Mammary Carcinogenesis. Anticancer research, 2022, Volume: 42, Issue:5 Topics: Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley	2022
Rutin Protects against Doxorubicin-Induced Cognitive Dysfunction While Retaining the Anticancer Potential of Dox in a Murine Model of N-Methyl-N-Nitrosourea - Induced Mammary Carcinoma. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2019, Volume: 38, Issue:2 Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cognitive Dysfunction; Doxorubicin; Female; Methylnitrosourea; Protective Agents; Rats; Rats, Sprague-Dawley; Rutin	2019
The American journal of Chinese medicine, 2019, Volume: 47, Issue:8 Topics: Animals; Breast Neoplasms; Down-Regulation; Drugs, Chinese Herbal; Estrogen Receptor alpha; Fatty Acid Synthases; Female; Humans; Methylnitrosourea; Mice; Mice, Nude; Nelumbo; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2	2019
Mitochondrial apoptosis and curtailment of hypoxia-inducible factor-1α/fatty acid synthase: A dual edge perspective of gamma linolenic acid in ER+ mammary gland cancer. Cell biochemistry and function, 2020, Volume: 38, Issue:5 Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Proliferation; Fatty Acid Synthases; Female; gamma-Linolenic Acid; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; MCF-7 Cells; Membrane Potential, Mitochondrial; Methylnitrosourea; Microscopy, Fluorescence; Mitochondria; Tumor Cells, Cultured	2020
Phenotypical Characteristics of Chemically Induced Mammary Tumor. Bulletin of experimental biology and medicine, 2017, Volume: 163, Issue:4 Topics: Animals; Breast Neoplasms; Cell Proliferation; ErbB Receptors; Female; Immunohistochemistry; Mammary Neoplasms, Animal; Methylnitrosourea; Rats; Rats, Wistar; Receptors, Progesterone	2017
Breast cancer amelioration by Butea monosperma in-vitro and in-vivo. Journal of ethnopharmacology, 2018, May-10, Volume: 217 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Butea; Cell Movement; Cell Proliferation; Chick Embryo; Dose-Response Relationship, Drug; Female; Humans; MCF-7 Cells; Methylnitrosourea; Neoplasm Invasiveness; Neovascularization, Pathologic; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Signal Transduction; Time Factors	2018
Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer. Breast cancer research : BCR, 2018, 06-14, Volume: 20, Issue:1 Topics: Animals; Aromatase; Breast; Breast Neoplasms; Disease Progression; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Animal; Metformin; Methylnitrosourea; Ovariectomy; Postmenopause; Rats; Stromal Cells; Tumor Microenvironment	2018
Effects of the pesticide chlorpyrifos on breast cancer disease. Implication of epigenetic mechanisms. The Journal of steroid biochemistry and molecular biology, 2019, Volume: 186 Topics: Animals; Breast Neoplasms; Chlorpyrifos; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 1; Humans; Methylnitrosourea; Pesticides; Rats; Rats, Sprague-Dawley	2019
Delphinidin suppresses breast carcinogenesis through the HOTAIR/microRNA-34a axis. Cancer science, 2019, Volume: 110, Issue:10 Topics: Animals; Anthocyanins; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enhancer of Zeste Homolog 2 Protein; Female; Gene Expression Regulation, Neoplastic; Histones; Humans; Methylnitrosourea; MicroRNAs; Rats; RNA, Long Noncoding; Wnt Signaling Pathway; Xenograft Model Antitumor Assays	2019
mTORC1/2 targeted by n-3 polyunsaturated fatty acids in the prevention of mammary tumorigenesis and tumor progression. Oncogene, 2014, Sep-11, Volume: 33, Issue:37 Topics: Animals; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Disease Progression; Fatty Acids, Omega-3; Female; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Methylnitrosourea; Mice; Mice, Nude; Mice, SCID; Multiprotein Complexes; Neoplasm Transplantation; Neovascularization, Pathologic; Rats; Signal Transduction; TOR Serine-Threonine Kinases	2014
Pubertal supplementation of lipotropes in female rats reduces mammary cancer risk by suppressing histone deacetylase 1. European journal of nutrition, 2014, Volume: 53, Issue:4 Topics: Animals; Breast Neoplasms; Choline; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Down-Regulation; Female; Folic Acid; Histone Deacetylase 1; Methionine; Methylnitrosourea; Micronutrients; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Vitamin B 12	2014
Dermcidin expression is associated with disease progression and survival among breast cancer patients. Breast cancer research and treatment, 2014, Volume: 144, Issue:2 Topics: Adenocarcinoma; Adult; Aged; Animals; Biomarkers, Tumor; Breast Neoplasms; Dermcidins; Disease Progression; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Middle Aged; Random Allocation; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
In vitro and in vivo efficacy of a novel quinuclidinone derivative against breast cancer. Anticancer research, 2014, Volume: 34, Issue:3 Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Immunoenzyme Techniques; In Vitro Techniques; Methylnitrosourea; Mitochondria; Quinuclidines; Rats; Rats, Wistar; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2014
Ampelopsin suppresses breast carcinogenesis by inhibiting the mTOR signalling pathway. Carcinogenesis, 2014, Volume: 35, Issue:8 Topics: Alkylating Agents; Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Proliferation; Cells, Cultured; Female; Flavonoids; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Immunoprecipitation; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Nude; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays	2014
Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2014, Volume: 23, Issue:6 Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Carcinogens; Celecoxib; Chemoprevention; Drug Synergism; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Pyrazoles; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfonamides	2014
Effect of Crocin on Cell Cycle Regulators in N-Nitroso-N-Methylurea-Induced Breast Cancer in Rats. DNA and cell biology, 2015, Volume: 34, Issue:11 Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carotenoids; Cell Cycle; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Female; Gene Expression Regulation, Neoplastic; Genes, p53; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats, Wistar	2015
Trypanosoma cruzi extracts elicit protective immune response against chemically induced colon and mammary cancers. International journal of cancer, 2016, Apr-01, Volume: 138, Issue:7 Topics: 1,2-Dimethylhydrazine; Animals; Antibodies, Protozoan; Antibody-Dependent Cell Cytotoxicity; Antigens, Protozoan; Breast Neoplasms; Cancer Vaccines; Carcinogens; Cell Line, Tumor; Colonic Neoplasms; Cross Reactions; Disease Models, Animal; Female; Flow Cytometry; Humans; Immunohistochemistry; Methylnitrosourea; Rats; Rats, Wistar; Trypanosoma cruzi	2016
Long chain n-3 polyunsaturated fatty acids increase the efficacy of docetaxel in mammary cancer cells by downregulating Akt and PKCε/δ-induced ERK pathways. Biochimica et biophysica acta, 2016, Volume: 1861, Issue:4 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorylation; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Taxoids; Time Factors; Transfection; Tumor Burden	2016
Anti-cancer effects of Piper nigrum via inducing multiple molecular signaling in vivo and in vitro. Journal of ethnopharmacology, 2016, Jul-21, Volume: 188 Topics: Angiogenic Proteins; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Breast Neoplasms; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Neoplasm Invasiveness; Neovascularization, Pathologic; Oxidative Stress; Phytotherapy; Piper nigrum; Plant Extracts; Plants, Medicinal; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Time Factors	2016
Physical activity induced protection against breast cancer risk associated with delayed parity. Physiology & behavior, 2017, 02-01, Volume: 169 Topics: Alkylating Agents; Animals; Breast Neoplasms; Collagen Type V; Cyclin-Dependent Kinase Inhibitor p57; Disease Models, Animal; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Methylnitrosourea; Parity; Physical Conditioning, Animal; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Reaction Time; Time Factors; Urokinase-Type Plasminogen Activator	2017
Disease Subtype-Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A. Journal of the National Cancer Institute, 2017, Volume: 109, Issue:6 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetyl Coenzyme A; Aldehyde Dehydrogenase 1 Family; Animals; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Cycle; Cytokines; Deoxyguanosine; Electron Transport Complex III; Female; Forkhead Transcription Factors; Humans; Ki-67 Antigen; Lactic Acid; Leptin; Malates; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; MCF-7 Cells; Methylnitrosourea; Mice; Mitosis; Mitotic Index; Rats; Receptors, Estrogen; Retinal Dehydrogenase; Retroviridae Infections; Signal Transduction; Tumor Burden; Tumor Virus Infections; Withanolides	2017
Analysis of caspase activities in rat mammary tumours induced by N-methyl-nitrosourea. Oncology reports, 2008, Volume: 20, Issue:3 Topics: Alkylating Agents; Animals; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 8; Caspase 9; Cytochromes c; Female; Mammary Neoplasms, Animal; Methylnitrosourea; Mitochondria; Rats; Rats, Wistar; Tumor Cells, Cultured	2008
Chemopreventive doses of methylselenocysteine alter circadian rhythm in rat mammary tissue. Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:2 Topics: Animals; Breast Neoplasms; Carcinoma; Cell Cycle Proteins; Chemoprevention; Circadian Rhythm; Cysteine; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Glands, Animal; Methylnitrosourea; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Period Circadian Proteins; Rats; Rats, Inbred F344; Selenium; Selenocysteine; Specific Pathogen-Free Organisms	2008
A surprising link between the energetics of ovariectomy-induced weight gain and mammary tumor progression in obese rats. Obesity (Silver Spring, Md.), 2010, Volume: 18, Issue:4 Topics: Alkylating Agents; Animals; Breast Neoplasms; Dietary Fats; Disease Models, Animal; Disease Progression; Energy Intake; Energy Metabolism; Estrogen Receptor alpha; Estrogens; Female; Interleukin-2; Interleukin-4; Menopause; Methylnitrosourea; Obesity; Ovariectomy; Ovary; Rats; Rats, Wistar; Sedentary Behavior; Weight Gain	2010
In vitro measures used to predict anticancer activity of apple cultivars and their comparison to outcomes from a rat model of experimentally induced breast cancer. Nutrition and cancer, 2009, Volume: 61, Issue:4 Topics: Adenocarcinoma; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Body Weight; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Flavonoids; Freeze Drying; Fruit; Humans; Hydroxybenzoates; Inhibitory Concentration 50; Malus; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytotherapy; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors	2009
Vitamin D3 affects expression of thyroid hormone receptor alpha and deiodinase activity in liver of MNU-treated Sprague-Dawley rats. General physiology and biophysics, 2009, Volume: 28, Issue:4 Topics: Animals; Body Weight; Breast Neoplasms; Calcitriol; Cholecalciferol; DNA; Female; Gene Expression Regulation; Iodide Peroxidase; Liver; Methylnitrosourea; Organ Size; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thyroid Hormone Receptors alpha	2009
Molecular histopathology by spectrally reconstructed nonlinear interferometric vibrational imaging. Cancer research, 2010, Dec-01, Volume: 70, Issue:23 Topics: Animals; Breast Neoplasms; Diagnostic Imaging; Female; Humans; Interferometry; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred WF; Reproducibility of Results; Sensitivity and Specificity; Spectrum Analysis, Raman; Vibration	2010
The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions. Breast cancer research : BCR, 2011, Aug-16, Volume: 13, Issue:4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Breast Neoplasms; CD4-Positive T-Lymphocytes; CD8 Antigens; Cytokines; Epithelial Cells; Female; Genetic Loci; Genetic Predisposition to Disease; Homeostasis; L-Selectin; Mammary Neoplasms, Experimental; Methylnitrosourea; NK Cell Lectin-Like Receptor Subfamily B; Rats; Rats, Inbred WKY; Receptors, Antigen, T-Cell; T-Lymphocytes; Th1 Cells; Th2 Cells	2011
Erufosine suppresses breast cancer in vitro and in vivo for its activity on PI3K, c-Raf and Akt proteins. Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:11 Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Class Ia Phosphatidylinositol 3-Kinase; Dose-Response Relationship, Drug; Female; Humans; Immunoblotting; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Mitogen-Activated Protein Kinases; Molecular Structure; Organophosphates; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; Quaternary Ammonium Compounds; ras Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Burden; Weight Loss	2012
Distinctive features of advancing breast cancer cells and interactions with surrounding stroma observed under the scanning electron microscope. Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:4 Topics: Animals; Breast Neoplasms; Cell Membrane; Female; Intercellular Junctions; Methylnitrosourea; Microscopy, Electron, Scanning; Rats; Rats, Sprague-Dawley	2012
Chemopreventive and anti-angiogenic effects of dietary phenethyl isothiocyanate in an N-methyl nitrosourea-induced breast cancer animal model. Biopharmaceutics & drug disposition, 2013, Volume: 34, Issue:2 Topics: Alkylating Agents; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Breast Neoplasms; Diet; Disease Models, Animal; Female; Isothiocyanates; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tumor Burden	2013
Defining the role of histone deacetylases in the inhibition of mammary carcinogenesis by dietary energy restriction (DER): effects of suberoylanilide hydroxamic acid (SAHA) and DER in a rat model. Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:4 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Caloric Restriction; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Vorinostat	2013
Serum pyrrolidone carboxypeptidase activity in N-methyl-nitrosourea induced rat breast cancer. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2003, Volume: 35, Issue:8 Topics: Animals; Biomarkers, Tumor; Body Weight; Breast Neoplasms; Carcinogens; Female; Methylnitrosourea; Pyroglutamyl-Peptidase I; Rats; Rats, Wistar; Regression Analysis	2003
Characterization of new estrogen receptor destabilizing compounds: effects on estrogen-sensitive and tamoxifen-resistant breast cancer. Journal of the National Cancer Institute, 2004, Feb-04, Volume: 96, Issue:3 Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Humans; Injections, Subcutaneous; Methylnitrosourea; Mice; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Transplantation, Heterologous	2004
Reduction of 1-methyl-1-nitrosourea-induced tumor burden with DNA vaccines encoding mutated ras epitopes and the costimulatory molecule B7.1. General physiology and biophysics, 2003, Volume: 22, Issue:4 Topics: Adenocarcinoma; Animals; B7-1 Antigen; Breast Neoplasms; Cancer Vaccines; Carcinogens; Feasibility Studies; Female; Genetic Therapy; Immunization; Methylnitrosourea; Mutagenesis, Site-Directed; Rats; Rats, Sprague-Dawley; Treatment Outcome; Vaccines, DNA	2003
Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells. Molecular cancer therapeutics, 2004, Volume: 3, Issue:8 Topics: Adenoviridae; Alkylating Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Dacarbazine; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Genetic Therapy; Genetic Vectors; Humans; Hydroxylamines; Immunohistochemistry; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Oligonucleotides; Sensitivity and Specificity; Sulfuric Acid Esters; Temozolomide; Time Factors	2004
Specific enkephalin-degrading aminopeptidase activity in the HPT and HPO axes of rats with breast cancer induced by N-methyl nitrosourea. Regulatory peptides, 2005, Jan-15, Volume: 124, Issue:1-3 Topics: Aminopeptidases; Animals; Breast Neoplasms; Enkephalins; Female; Hypothalamus; Methylnitrosourea; Pituitary Gland; Rats; Rats, Wistar; Thyroid Gland	2005
Gene expression profiling of NMU-induced rat mammary tumors: cross species comparison with human breast cancer. Carcinogenesis, 2005, Volume: 26, Issue:8 Topics: Animals; Breast; Breast Neoplasms; Carcinogens; Cluster Analysis; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Animal; Methylnitrosourea; Rats; Rats, Inbred WF; Species Specificity	2005
Inhibition of NMU-induced mammary tumorigenesis by dietary soy. Cancer letters, 2005, Jun-16, Volume: 224, Issue:1 Topics: Alkylating Agents; Animals; Apoptosis; Breast Neoplasms; Cell Proliferation; Chemoprevention; Diet; Disease Models, Animal; Female; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Receptor, ErbB-2; Receptors, Progesterone; Soybean Proteins	2005
ET(B) receptor agonist, IRL 1620, does not affect paclitaxel plasma pharmacokinetics in breast tumour bearing rats. The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:7 Topics: Alkylating Agents; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Drug Interactions; Endothelins; Female; Methylnitrosourea; Paclitaxel; Peptide Fragments; Rats; Rats, Sprague-Dawley	2005
Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:14 Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Heme; Heme Oxygenase-1; Humans; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lentivirus; Mammary Neoplasms, Animal; Methylnitrosourea; Oxygen; Protein Processing, Post-Translational; Rats; RNA, Small Interfering; Signal Transduction	2005
Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism. Breast cancer research : BCR, 2005, Volume: 7, Issue:6 Topics: Adjuvants, Immunologic; Alkylating Agents; Animals; Breast Neoplasms; Carcinoma in Situ; Cell Transformation, Neoplastic; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Dehydroepiandrosterone; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53	2005
Open access to breast tumours. The Lancet. Oncology, 2006, Volume: 7, Issue:3 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Drug Delivery Systems; Humans; Mammary Neoplasms, Animal; Methylnitrosourea; Mice; Mice, Transgenic; Rats	2006
Effects of liarozole fumarate (R85246) in combination with tamoxifen on N-methyl-N-nitrosourea (MNU)-induced mammary carcinoma and uterus in the rat model. BMC cancer, 2007, Jan-31, Volume: 7 Topics: Animals; Breast Neoplasms; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Female; Imidazoles; Methylnitrosourea; Ovariectomy; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus	2007
A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models. Breast cancer research and treatment, 2007, Volume: 106, Issue:2 Topics: Administration, Oral; Animals; Breast Neoplasms; Cell Proliferation; Coumarins; Cricetinae; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrone; Female; Gene Expression Regulation, Enzymologic; Humans; Leukocytes; Methylnitrosourea; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Signal Transduction; Steryl-Sulfatase; Sulfonamides; Sulfonic Acids; Tamoxifen; Tumor Cells, Cultured	2007
Prenatal bisphenol A exposure induces preneoplastic lesions in the mammary gland in Wistar rats. Environmental health perspectives, 2007, Volume: 115, Issue:1 Topics: Alkylating Agents; Animals; Benzhydryl Compounds; Breast Neoplasms; Estrogens, Non-Steroidal; Female; Mammary Glands, Animal; Methylnitrosourea; Phenols; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Sexual Maturation	2007
Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens. Cancer research, 2007, Dec-01, Volume: 67, Issue:23 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Animals; Animals, Genetically Modified; Blotting, Western; Breast; Breast Neoplasms; Carcinogens; Cells, Cultured; Female; Gene Silencing; Genes, ras; Glutathione Peroxidase; Humans; Imidazoles; Mammary Neoplasms, Experimental; Methylnitrosourea; Middle Aged; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tumor Suppressor Protein p53	2007
Hormones of pregnancy, alpha-feto protein, and reduction of breast cancer risk. Advances in experimental medicine and biology, 2008, Volume: 617 Topics: alpha-Fetoproteins; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Chorionic Gonadotropin; Estradiol; Estriol; Estrogens; Female; Humans; Liver Neoplasms; Methylnitrosourea; Pregnancy; Progesterone; Rats; Reproductive Control Agents; Risk Factors; Tumor Cells, Cultured	2008
Ultrastructural study of membrane glycocalyx in primary and metastatic human and rat mammary carcinoma. Journal of surgical oncology, 1981, Volume: 17, Issue:4 Topics: Animals; Breast Neoplasms; Cell Membrane; Female; Glycoproteins; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Microscopy, Electron; Neoplasm Transplantation; Polysaccharides; Rats; Ruthenium Red	1981
[Tamoxifen as a suppressor of mammary carcinogenesis induced by 7,12-dimethyl-benzanthracene and methylnitrosourea, in female rats with induced hyperprolactinemia]. Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina), 1983, Volume: 41, Issue:3-4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Methylnitrosourea; Nitrosourea Compounds; Prolactin; Rats; Sulpiride; Tamoxifen	1983
[Changes in the proliferative activity of human breast cancer cells cultivated in vivo in diffusion chambers in response to antineoplastic agents]. Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 92, Issue:7 Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma; Diazonium Compounds; Drug Evaluation, Preclinical; Humans; Methylnitrosourea; Mice; Mice, Inbred CBA; Mitotic Index; Neoplasm Transplantation; Nitrosourea Compounds; Succinates; Thiotepa; Transplantation, Heterologous	1981
Pituitary responses to thyrotropin-releasing hormone after treatment with the breast carcinogen nitrosomethylurea: inhibition of prolactin but not thyrotropin release. Endocrinology, 1982, Volume: 110, Issue:6 Topics: Animals; Breast Neoplasms; Female; Methylnitrosourea; Nitrosourea Compounds; Pituitary Gland; Prolactin; Rats; Rats, Inbred BUF; Thyrotropin; Thyrotropin-Releasing Hormone	1982
Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production. Cancer research, 1981, Volume: 41, Issue:7 Topics: Animals; Autoradiography; Basement Membrane; Breast Neoplasms; Cell Line; Collagen; Female; Fluorescent Antibody Technique; Humans; Hydroxyproline; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Proline; Protein Biosynthesis; Rats	1981
Hormone dependency in N-nitrosomethylurea-induced rat mammary tumors. Endocrinology, 1982, Volume: 111, Issue:2 Topics: Adenocarcinoma; Animals; Breast Neoplasms; Estradiol; Female; Hypophysectomy; Methylnitrosourea; Neoplasms, Hormone-Dependent; Nitrosourea Compounds; Prolactin; Rats; Rats, Inbred Strains; Receptors, Estrogen	1982
Treatment of metastatic brain tumors with the combination of 1-methyl-1-nitrosourea (MNU) and cyclophosphamide. Journal of cancer research and clinical oncology, 1980, Volume: 97, Issue:2 Topics: Adult; Aged; Brain Neoplasms; Breast Neoplasms; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Dysgerminoma; Esophageal Neoplasms; Female; Humans; Lung Neoplasms; Male; Melanoma; Methylnitrosourea; Middle Aged; Nitrosourea Compounds; Parotid Neoplasms; Testicular Neoplasms	1980
Chromatographic investigations of estradiol receptor from breast cancer tissue. Folia biologica, 1993, Volume: 39, Issue:6 Topics: Animals; Breast Neoplasms; Chromatography, Ion Exchange; Ethanolamines; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Receptors, Estradiol	1993
Prevention of breast cancer in the rat with 9-cis-retinoic acid as a single agent and in combination with tamoxifen. Cancer research, 1994, Sep-01, Volume: 54, Issue:17 Topics: Animals; Breast Neoplasms; Drug Screening Assays, Antitumor; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen; Tretinoin; Tumor Cells, Cultured	1994
1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol (Ro24-5531), a new deltanoid (vitamin D analogue) for prevention of breast cancer in the rat. Cancer research, 1994, Apr-01, Volume: 54, Issue:7 Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Breast Neoplasms; Calcitriol; Calcium; Cell Division; Cell Line; Diet; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Invasiveness; Rats; Rats, Sprague-Dawley; Tamoxifen; Tumor Cells, Cultured	1994
A rapid dual organ rat carcinogenesis bioassay for evaluating the chemoprevention of breast and colon cancer. Cancer letters, 1996, Feb-27, Volume: 100, Issue:1-2 Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Breast Neoplasms; Carcinogenicity Tests; Carcinogens; Cocarcinogenesis; Colonic Neoplasms; Dietary Fats; Dietary Fiber; Drug Screening Assays, Antitumor; Evaluation Studies as Topic; Female; Methylnitrosourea; Phytic Acid; Rats; Rats, Sprague-Dawley	1996
Detection of breast cancer-associated estrone sulfatase in breast cancer biopsies and cell lines using polymerase chain reaction. The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:2 Topics: Animals; Antineoplastic Agents, Hormonal; Base Sequence; Biopsy; Blotting, Northern; Breast Neoplasms; Carcinogens; DNA Primers; DNA, Complementary; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Molecular Sequence Data; Polymerase Chain Reaction; Rats; RNA, Neoplasm; Sulfatases; Tamoxifen; Tumor Cells, Cultured	1993
Hormonal prevention of breast cancer: mimicking the protective effect of pregnancy. Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-02, Volume: 96, Issue:5 Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Cell Differentiation; Cell Division; Estradiol; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Perphenazine; Pregnancy; Progesterone; Rats; Rats, Inbred Lew	1999
Polyunsaturated fatty acids and breast cancer. Lipids, 1999, Volume: 34 Suppl Topics: Animals; Antineoplastic Agents; Brassica; Breast Neoplasms; Cell Survival; Dietary Fats, Unsaturated; Fatty Acids, Monounsaturated; Female; Fish Oils; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Plant Oils; Rapeseed Oil; Tumor Cells, Cultured	1999
The effect of 2-methoxyoestrone-3-O-sulphamate on the growth of breast cancer cells and induced mammary tumours. International journal of cancer, 2000, Feb-15, Volume: 85, Issue:4 Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Cycle; Cell Division; Estrone; Female; G2 Phase; Humans; Hydroxyestrones; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitosis; Rats; Receptors, Estrogen; Tumor Cells, Cultured	2000
Detection of VIP receptors in MNU-induced breast cancer in rats: implications for breast cancer targeting. Breast cancer research and treatment, 2001, Volume: 65, Issue:1 Topics: Alkylating Agents; Animals; Breast Neoplasms; Cell Transformation, Neoplastic; Female; Fluorescein; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Vasoactive Intestinal Peptide	2001
VIP receptors as molecular targets of breast cancer: implications for targeted imaging and drug delivery. Journal of controlled release : official journal of the Controlled Release Society, 2001, Jul-06, Volume: 74, Issue:1-3 Topics: Animals; Breast Neoplasms; Carcinogens; Drug Delivery Systems; Female; Fluorescent Dyes; Liposomes; Mammary Neoplasms, Experimental; Methylnitrosourea; Polyethylene Glycols; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, Vasoactive Intestinal Peptide	2001
Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation. The Journal of endocrinology, 2001, Volume: 171, Issue:1 Topics: Animals; Breast Neoplasms; Bromodeoxyuridine; Carcinogens; Cell Division; Estradiol; Female; Fluorescent Antibody Technique; Mammary Glands, Animal; Methylnitrosourea; Progesterone; Rats; Rats, Inbred WF; Receptors, Estrogen	2001
Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. Molecular carcinogenesis, 2002, Volume: 33, Issue:1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Southern; Breast Neoplasms; Carcinogens; Carcinoma in Situ; Carcinoma, Ductal, Breast; Chromosome Aberrations; DNA, Neoplasm; Estrogens; Female; Genes, myc; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Invasiveness; Ploidies; Rats; Rats, Inbred ACI; Rats, Sprague-Dawley; Testosterone	2002
Tumor prevention by 9-cis-retinoic acid in the N-nitroso-N-methylurea model of mammary carcinogenesis is potentiated by the pineal hormone melatonin. Breast cancer research and treatment, 2002, Volume: 72, Issue:1 Topics: Administration, Oral; Alitretinoin; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tretinoin	2002
The growth hormone-deficient Spontaneous Dwarf rat is resistant to chemically induced mammary carcinogenesis. Carcinogenesis, 2002, Volume: 23, Issue:6 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Cell Division; Crosses, Genetic; Disease Models, Animal; Dwarfism; Female; Growth Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley	2002
Analysis of mammary tumors for cytochemical evidence of endogenous mammary peroxidase. Virchows Archiv. B, Cell pathology including molecular pathology, 1979, Volume: 31, Issue:2 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Peroxidases; Pregnancy; Rats	1979
Combination chemotherapy with 1-methyl-1-nitrosourea (MNU) and cyclophosphamide in solid tumors. Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1977, Aug-15, Volume: 89, Issue:3 Topics: Adult; Alopecia; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Leukopenia; Male; Melanoma; Methylnitrosourea; Middle Aged; Nausea; Nitrosourea Compounds	1977
In vitro investigations on the antineoplastic effect of hexadecylphosphocholine. Arzneimittel-Forschung, 1991, Volume: 41, Issue:6 Topics: Animals; Antineoplastic Agents; Bone Marrow Cells; Breast Neoplasms; Colony-Forming Units Assay; Humans; KB Cells; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Nitrosourea Compounds; Phospholipid Ethers; Phosphorylcholine; Rats; Rats, Inbred Strains; Tumor Cells, Cultured	1991
Pyrrolidino-4-iodotamoxifen and 4-iodotamoxifen, new analogues of the antiestrogen tamoxifen for the treatment of breast cancer. Cancer research, 1991, Nov-01, Volume: 51, Issue:21 Topics: Animals; Breast Neoplasms; Cell Division; Cell Line; Drug Screening Assays, Antitumor; Estradiol Congeners; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen	1991
Cellular ras protooncogene expression in human mammary explant cultures. A potential marker for chemical carcinogenesis. Annals of the New York Academy of Sciences, 1990, Volume: 586 Topics: Adult; Benzo(a)pyrene; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Female; Genes, ras; Humans; Methylnitrosourea; Middle Aged; Organ Specificity; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras)	1990
Role of transforming growth factor-alpha-related peptides in the autocrine/paracrine control of experimental breast cancer growth in vitro by estradiol, prolactin, and progesterone. Breast cancer research and treatment, 1990, Volume: 15, Issue:2 Topics: Animals; Antibodies, Monoclonal; Breast Neoplasms; ErbB Receptors; Estradiol; Female; Humans; In Vitro Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Prolactin; Rats; Rats, Inbred Strains; Transforming Growth Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay	1990
[In vitro study of estradiol-linked nitrosourea in breast cancers in the mouse, rat and human: interspecies comparison]. Wiener klinische Wochenschrift, 1989, Feb-17, Volume: 101, Issue:4 Topics: Animals; Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Cell Division; Cell Survival; Colony-Forming Units Assay; Estradiol; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Transplantation; Nitrogen Mustard Compounds; Rats; Rats, Inbred Strains; Species Specificity; Tumor Cells, Cultured; Tumor Stem Cell Assay	1989
Possible role for vitamin D in controlling breast cancer cell proliferation. Lancet (London, England), 1989, Jan-28, Volume: 1, Issue:8631 Topics: Adult; Aged; Aged, 80 and over; Animals; Breast Neoplasms; Cell Differentiation; Cell Division; Female; Humans; Hydroxycholecalciferols; Mammary Neoplasms, Experimental; Methylnitrosourea; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Rats; Receptors, Calcitriol; Receptors, Steroid; Time Factors; Tumor Cells, Cultured; Vitamin D	1989
Independent molecular pathways in initiation and loss of hormone responsiveness of breast carcinomas. Science (New York, N.Y.), 1988, Apr-22, Volume: 240, Issue:4851 Topics: Animals; Breast Neoplasms; Cell Line; Estrogens; Gene Expression Regulation; Genes, ras; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Receptors, Estrogen	1988
In vitro evaluation of an estradiol-linked nitrosourea in mammary carcinomas of mouse, rat and man. European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:6 Topics: Adult; Aged; Animals; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Estradiol; Ethylnitrosourea; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Middle Aged; Nitrogen Mustard Compounds; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Tumor Stem Cell Assay	1988
Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response. Cancer research, 1986, Volume: 46, Issue:9 Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Dihydrotestosterone; Female; Humans; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Ovariectomy; Rats; Tamoxifen	1986
The inhibitory effect of 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) on estrogen-dependent mammary tumors. European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:4 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Indoles; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen	1985