methylnitrosourea has been researched along with Body Weight in 132 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (26.52) | 18.7374 |
| 1990's | 46 (34.85) | 18.2507 |
| 2000's | 36 (27.27) | 29.6817 |
| 2010's | 12 (9.09) | 24.3611 |
| 2020's | 3 (2.27) | 2.80 |
| Authors | Studies |
|---|---|
| Saedmocheshi, S; Saghebjoo, M; Sheikholeslami-Vatani, D; Vahabzadeh, Z | 1 |
| Adaramoye, OA; Adefisan, AO; Madu, JC; Owumi, SE | 1 |
| Donahue, DA; Hayashi, SM; Koyanagi, M; Mahapatra, D; Maronpot, RR; Nyska, A | 1 |
| Ansari, MN; Choudhary, A; Kaithwas, G; Kumar, D; Raj, R; Rastogi, S; Saeedan, AS; Singh, L; Singh, M | 1 |
| Jian, YM; Sun, YN; Zhuang, S | 1 |
| Bae, S; Cho, K; Mabasa, L; Park, CS; Walters, MW | 1 |
| Emilia, ST; Shaari, R; Yaacob, NS; Yankuzo, HM | 1 |
| Boonyaphiphat, P; Deng, Y; Graidist, P; Lailerd, N; Nitiruangjarat, A; Sriwiriyajan, S; Tedasen, A | 1 |
| Cohick, WS; Globerman, SP; Saboya, M; Stires, H | 1 |
| Ando, M; Inoue, Y; Iwase, Y; Kato, T; Muto, S; Uno, Y; Yamada, K | 1 |
| Fetisovova, Z; Kajo, K; Kubatka, P; Machalekova, K; Nosalova, G; Ostatnikova, D; Sadlonova, V | 1 |
| Adamicova, K; Kajo, K; Kubatka, P; Nosalova, G; Ostatnikova, D; Sadlonova, J; Sadlonova, V | 1 |
| Furihata, C; Kaminishi, M; Seto, Y; Shimizu, N; Tatematsu, M; Yamaguchi, H; Yamamoto, M; Yoshizawa, N | 1 |
| Maffini, MV; Murray, TJ; Sonnenschein, C; Soto, AM; Ucci, AA | 1 |
| McGinley, JN; Stushnoff, C; Thompson, HJ; Thompson, MD | 1 |
| Kawanaka, A; Kuwata, M; Tsubura, A; Uehara, N; Yoshizawa, K; Yuri, T | 1 |
| Brtko, J; Macejová, D; Ondková, S | 1 |
| Fujiyama, F; Komada, M; Nagao, T; Shiota, K; Yamada, S | 1 |
| Arunakaran, J; Arunkumar, R; Banudevi, S; Elumalai, P; Gunadharini, DN; Senthilkumar, K; Sharmila, G | 1 |
| Kokare, DM; Kotwal, SD; Nakhate, KT; Singru, PS; Subhedar, NK; Taksande, AG | 1 |
| Evans, EM; Layman, DK; Moulton, CJ; Thorpe, MP; Valentine, RJ; Wagoner Johnson, AJ | 1 |
| Murasaki, T; Nakanishi, M; Ogawa, K; Shirai, T; Sugiura, S | 1 |
| Anderson, AS; Eto, I; Grizzle, WE; Grubbs, CJ; Johanning, GL; Rodríguez-Burford, C; Steele, VE; Stockard, CR; Weiss, HL | 1 |
| Fukaura, Y; Narisawa, T | 1 |
| Choi, M; Hwang, SW; Kim, YI; Kotsopoulos, J; Martin, R; McKerlie, C; Medline, A; Renlund, R; Sohn, KJ | 1 |
| Jiang, W; Thompson, HJ; Zhu, Z | 1 |
| Bacchi, MM; da Silva Franchi, CA; de Camargo, JL; Padovani, CR | 1 |
| Carrera, MP; García, MJ; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ; Valenzuela, MT | 2 |
| Atigadda, VR; Beenken, SW; Bland, KI; Brouillette, WJ; Eto, I; Grubbs, CJ; Hill, DL; Lin, TH; Muccio, DD; Vines, KK | 1 |
| Danbara, N; Nakane, Y; Pei, RJ; Sato, M; Tsubura, A; Yuri, T | 1 |
| Jiang, W; McGinley, JN; Thompson, HJ; Zhu, Z | 1 |
| Lee, S; Nimmo, M; Simpson, M; Xu, Z | 1 |
| Charbonneau, M; Cole, J; Desaulniers, D; Leingartner, K; Li, M; Musicki, B; Tsang, BK | 1 |
| Kijkuokool, P; Malaivijitnond, S; Parhar, IS | 1 |
| Asaka, M; Kato, S; Katsuyama, T; Kumagai, T; Mizoshita, T; Ota, H; Tanaka, H; Tatematsu, M; Tsukamoto, T | 1 |
| Bhattacharjee, D; Hoshi, M; Ito, A; Yin, H | 1 |
| Bellinaso, Mde L; de Vargas Barbosa, NB; Guecheva, TN; Nogueira, CW; Rocha, JB | 1 |
| Bisson, JF; Guardia-Llorens, MA; Hidalgo, S; Messaoudi, M; Rozan, P | 1 |
| Fetisovova, Z; Kajo, K; Kubatka, P; Nosalova, G; Sadlonova, V | 1 |
| de Groot, AJ; Jansen, JG; Mohn, GR; Mullenders, LF; van Duijn-Goedhart, AM; van Oostrom, C; van Steeg, H; van Zeeland, AA | 1 |
| Starling, JR; Syrjala, S; Weese, JL | 1 |
| King, MM; McCay, PB | 1 |
| Takeuchi, IK | 1 |
| Luckert, PH; Pollard, M | 2 |
| Berger, MR; Munder, PG; Schmähl, D; Westphal, O | 1 |
| Ohshima, M; Ward, JM | 2 |
| King, MM; Kosanke, SD; McCay, PB | 1 |
| Becci, PJ; Brown, CC; Moon, RC; Newton, DL; Nürrenbach, A; Paust, J; Sporn, MB; Thompson, HJ | 1 |
| Becci, PJ; Meeker, LD; Thompson, HJ | 1 |
| Althoff, J; Brune, H; Deutsch-Wenzel, R; Green, U; Schneider, P | 1 |
| Grossman, HB; Lesser, ML; Sonda, LP | 1 |
| Chowaniec, J; Grasso, P; Hicks, RM; Hooson, J | 1 |
| Ando, Y; Fujimoto, N; Ito, A; Kanin, GN; Kawamoto, K; Okamoto, T; Watanabe, H; Yamada, K | 1 |
| Fukaura, Y; Ishikawa, C; Isoda, Y; Narisawa, T; Nishizawa, Y; Yazawa, K | 1 |
| Jang, JJ; Lee, YS | 1 |
| Hasegawa, R; Ito, N; Nagao, M; Shirai, T; Sugimura, T; Tamano, S; Tanaka, H | 1 |
| Berger, MR; Drevs, J; Eibl, H; Kaufmann-Kolle, P; Kötting, J; Marschner, N; Unger, C | 1 |
| Fujimoto, N; Ito, A; Ogundigie, PO; Okamoto, T; Watanabe, H | 1 |
| Fukushima, S; Futakuchi, M; Hirose, M; Ito, N; Takahashi, S; Tanaka, H | 1 |
| Bird, RP; Magnuson, BA | 1 |
| Mori, H; Morishita, Y; Sasaki, S; Tanaka, T | 1 |
| Asakawa, E; Fukushima, S; Kawabe, M; Sano, M; Shioya, S; Shirai, T; Tamano, S; Tanaka, H | 1 |
| Boonyaphiphat, P; Cabral, R; Hakoi, K; Hasegawa, R; Hoshiya, T; Ito, N; Ogiso, T; Shirai, T | 1 |
| Pereira, MA; Phelps, JB | 1 |
| Meeker, LD; Ronan, AM; Scott, AL; Sinha, D; Tagliaferro, AR; Thompson, HJ | 1 |
| Aizawa, R; Fukaura, Y; Hasebe, M; Ito, M; Morotomi, M; Narisawa, T | 1 |
| Borges, A; Ingle, A; Kothari, A; Kothari, L | 1 |
| Kramer, PM; Li, K; Pereira, MA | 1 |
| Binasco, V; Chiara, M; Dianzani, MU; Premoselli, F; Sesca, E; Tessitore, L | 1 |
| Asamoto, M; Kim, DJ; Kim, JM; Murakoshi, M; Nir, Z; Nishino, H; Ota, T; Sekine, K; Takasuka, N; Tsuda, H | 1 |
| Archer, MC; Lee, WM; Lu, S | 1 |
| Fukushima, S; Inada, K; Kobayashi, K; Nakanishi, H; Shimizu, N; Tatematsu, M; Tsukamoto, T; Yamachika, T | 1 |
| Birt, DF; Blackwood, D; Harvell, DM; Markin, RS; Pennington, KL; Shull, JD | 1 |
| Dohi, K; Gotoh, T; Ito, A; Kataoka, T; Yamada, K; Yin, H | 1 |
| Bosland, MC; Dooley, L; Kelloff, GJ; Lubet, RA; McCormick, DL; Rao, KV; Steele, VE | 1 |
| Barotto, NN; Eynard, AR; Fernández Zapico, ME; López, CB; Valentich, MA | 1 |
| Bowden, C; DeCoster, R; Eto, I; Grubbs, CJ; Juliana, MM; Kelloff, GJ; Lubet, RA; Steele, VE; You, M | 1 |
| Furihata, C; Ikehara, Y; Inada, K; Kobayashi, K; Tatematsu, M; Tsukamoto, T; Yamamoto, M | 1 |
| Hirose, M; Shibutani, M; Shoda, T; Takada, K; Takahashi, M; Tamura, T; Toyoda, K; Uneyama, C | 1 |
| Hendry, JH; Hoyes, KP; Lord, BI | 1 |
| Barbisan, LF; Fávero Salvadori, DM; Kaneno, R; Marchesan Rodrigues, MA; Spinardi-Barbisan, AL; Trindade Moreira, EL; Viana de Camargo, JL | 1 |
| Chen, B; Wang, G; Wang, P; Zhou, S | 1 |
| Rickard, SE; Thompson, LU; Yuan, YV | 1 |
| Hashimoto, M; Lian, Z; Mori, H; Morishita, S; Niwa, K; Tagami, K; Tamaya, T | 1 |
| Anderson, MB; Blask, DE; Cheng, Q; Collins, A; Dai, J; Dwivedi, PD; Hill, SM; Kiefer, TL; Moroz, K; Myers, L; Spriggs, LL; Teplitzky, SR; Yuan, L | 1 |
| Hirano, K; Itoh, F; Kominami, G; Nara, H; Ohno, K; Tasaki, T; Torii, M; Yabuuchi, K | 1 |
| Ahn, B; Choi, M; Jang, DD; Kang, JS; Kim, DJ; Kim, KS; Nam, KT | 1 |
| Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Cermáková, M; Chamilová, M; Kalická, K; Kubatka, P | 1 |
| Bigsby, RM | 1 |
| Chan, PC; Cohen, LA; Head, JF; Wynder, EL | 1 |
| Momose, H; Oyasu, R; Rademaker, A; Wu, HH; Yamamoto, M | 1 |
| Arnold, W; Fichtner, I; Görlich, M; Hauff, P; Staab, HJ; Winterfeld, G | 1 |
| Berger, MR; Bunk, B; Klinga, K; Schmähl, D; Zhu, P | 1 |
| Fukaura, Y; Isoda, Y; Kotanagi, H; Kotsugai, M; Koyama, H; Kusaka, H; Narisawa, T; Nishizawa, Y; Takahashi, M; Yamazaki, Y | 1 |
| Cohen, LA; Kendall, ME; Meschter, C; Rose, DP; Zang, E | 1 |
| Blair, WH; Hawrylewicz, EJ; Huang, HH | 1 |
| Furui, T; Mori, H; Niwa, K; Tamaya, T; Tanaka, T; Yokoyama, Y | 1 |
| Hashimoto, Y; Mizutani, M | 1 |
| Iwasaki, S; Masui, T; Shirai, T; Tamano, S; Yamamoto, A | 1 |
| Thompson, HJ | 1 |
| Monis, B; Valentich, MA | 1 |
| Juzefyk, J; Kennedy, K; Thompson, HJ; Witt, M | 1 |
| Bae, JH; Cho, KJ; Jang, JJ; Lee, YS | 1 |
| Berger, MR; Bunk, B; Frei, E; Schmähl, D; Zhu, P | 1 |
| Bosland, MC; Prinsen, MK | 1 |
| Exon, JH; Koller, LD; Talcott, PA | 1 |
| Dohi, K; Ito, A; Mori, M; Naito, M; Takeichi, N; Watanabe, H | 1 |
| Kawaura, A; Maekawa, S; Oda, M; Sawada, K; Sawada, Y; Shimoyama, T; Takahashi, A; Tanida, N | 1 |
| Birt, DF; Bresnick, E; Markin, RS; Wheeler, M; Wolterman, K | 1 |
| Hirose, M; Ito, N; Shibata, M; Shirai, T; Tanaka, H | 1 |
| Fujiki, H; Fukaura, Y; Narisawa, T; Niwa, M; Takahashi, M | 1 |
| Cohen, SM; Garland, EM; Mann, AM; Masui, T | 1 |
| McCormick, DL; Moon, RC | 1 |
| Hawrylewicz, EJ | 1 |
| Kawaura, A; Narisawa, T; Sawada, K; Shimoyama, T; Tanida, N | 1 |
| Ahmed, SR; Badger, B; Bartholomew, M; Caplan, R; Luk, G; Manni, A; Rockette, H; Wright, C | 1 |
| Baxter, CS; Loch-Caruso, R | 1 |
| Choi, KW; Cohen, LA; Wang, CX | 1 |
| Bond, SL; Singh, SM | 1 |
| Blank, ME; Choi, K; Cohen, LA; Maeura, Y; Rose, DP; Thompson, DO | 1 |
| Aksoy, M; Berger, MR; Beth, M; Schmähl, D | 2 |
| Aksoy, M; Berger, MR; Schmähl, D | 1 |
| Hawrylewicz, EJ; Huang, HH; Liu, JM | 1 |
| Hard, GC; Jensen, DE; Magee, PN; Ogiu, T | 1 |
| Luo, XM; Wei, HJ; Yang, SP | 1 |
| Diwan, BA; Ohshima, M; Palmer, AE; Rice, JM | 1 |
| Manni, A; Pontari, M; Wright, C | 1 |
| Goad, ME; Lindenschmidt, RC; Tryka, AF; Witschi, HP | 1 |
1 review(s) available for methylnitrosourea and Body Weight
| Article | Year |
|---|---|
Fat-protein interaction, defined 2-generation studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cell Transformation, Neoplastic; Cocarcinogenesis; Dietary Fats; Dietary Proteins; Disease Models, Animal; Eating; Epidemiologic Methods; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Thymidine | 1986 |
131 other study(ies) available for methylnitrosourea and Body Weight
| Article | Year |
|---|---|
Aerobic Training and Green Tea Extract Protect against N-methyl-N-nitrosourea-induced Prostate Cancer.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Cyclooxygenase 2; Male; Methylnitrosourea; NF-kappa B; Organ Size; Physical Conditioning, Animal; Plant Extracts; Prostate; Prostatic Neoplasms; Rats, Wistar; Tea; Tumor Suppressor Protein p53 | 2019 |
Topics: Animals; bcl-2-Associated X Protein; Benzo(a)pyrene; Biomarkers; Body Weight; Fabaceae; Female; Hormones; Inflammation; Methylnitrosourea; Organ Size; Ovary; Oxidation-Reduction; Plant Extracts; Rats, Sprague-Dawley; Uterus; Vincristine | 2020 |
alpha-Glycosyl Isoquercitrin (AGIQ) and its lack of carcinogenicity in rasH2 mice.
Topics: Animals; Body Weight; Carcinogenicity Tests; Dose-Response Relationship, Drug; Feeding Behavior; Female; Food Additives; Male; Methylnitrosourea; Mice; Mice, Transgenic; No-Observed-Adverse-Effect Level; Organ Size; Quercetin | 2021 |
Effect of Voacamine upon inhibition of hypoxia induced fatty acid synthesis in a rat model of methyln-nitrosourea induced mammary gland carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Body Weight; Carcinoma; Computer Simulation; Electrocardiography; Fatty Acids; Female; Heart Rate; Hypoxia-Inducible Factor-Proline Dioxygenases; Ibogaine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Metabolome; Methylnitrosourea; Neovascularization, Pathologic; Rats, Wistar; Tamoxifen | 2021 |
Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice.
Topics: Adiponectin; Animals; Blood Glucose; Body Weight; Carcinogenesis; Cell Transformation, Neoplastic; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Immunohistochemistry; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Ki-67 Antigen; Leptin; Male; Methylnitrosourea; Mice; Stomach Neoplasms | 2017 |
Maternal dietary canola oil suppresses growth of mammary carcinogenesis in female rat offspring.
Topics: Animals; Body Weight; Carcinogenesis; Diet; Dietary Fats; Disease Models, Animal; Fatty Acids, Monounsaturated; Female; Lactation; Mammary Neoplasms, Experimental; Maternal Nutritional Physiological Phenomena; Methylnitrosourea; Pregnancy; Rapeseed Oil; Rats; Rats, Sprague-Dawley | 2013 |
Correlation of tumour response with starting tumour size and dose of tamoxifen in an N-methyl-N-nitrosourea (NMU)-induced rat mammary cancer model.
Topics: Animals; Body Weight; Creatinine; Drug Dosage Calculations; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Random Allocation; Rats; Rats, Sprague-Dawley; Tamoxifen; Treatment Outcome; Tumor Burden; Urea | 2014 |
Anticancer and Cancer Prevention Effects of Piperine-Free Piper nigrum Extract on N-nitrosomethylurea-Induced Mammary Tumorigenesis in Rats.
Topics: Alkaloids; Animals; Anticarcinogenic Agents; Apoptosis; Benzodioxoles; Body Weight; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Mice; Mice, Inbred ICR; Piper nigrum; Piperidines; Plant Extracts; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley | 2016 |
Peroral Estradiol Is Sufficient to Induce Carcinogen-Induced Mammary Tumorigenesis in Ovariectomized Rats without Progesterone.
Topics: Animals; Body Weight; Carcinogenesis; Carcinogens; Cell Proliferation; Estradiol; Female; Immunohistochemistry; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Ovariectomy; Progesterone; Rats, Sprague-Dawley; Time Factors; Uterus | 2016 |
Evaluation of the mutagenicity of alkylating agents, methylnitrosourea and temozolomide, using the rat Pig-a assay with total red blood cells or reticulocytes.
Topics: Alkylating Agents; Animals; Body Weight; Dacarbazine; Erythrocytes; Male; Membrane Proteins; Methylnitrosourea; Mutagenicity Tests; Mutagens; Rats; Rats, Sprague-Dawley; Reticulocytes; Temozolomide | 2016 |
Neoplastic effects of exemestane in premenopausal breast cancer model.
Topics: Androstadienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Body Weight; Drug Evaluation, Preclinical; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Premenopause; Rats; Rats, Sprague-Dawley | 2008 |
Side effects of anastrozole in the experimental pre-menopausal mammary carcinogenesis.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitriles; Rats; Rats, Sprague-Dawley; Triazoles; Uterus; Vagina | 2009 |
Gastric carcinogenesis by N-Methyl-N-nitrosourea is enhanced in db/db diabetic mice.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Diabetes Complications; Disease Models, Animal; Gastric Mucosa; Insulin; Leptin; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Precancerous Conditions; Stomach Neoplasms | 2009 |
Histological analysis of low dose NMU effects in the rat mammary gland.
Topics: Animals; Body Weight; Disease Models, Animal; Female; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar; Species Specificity; Time Factors | 2009 |
In vitro measures used to predict anticancer activity of apple cultivars and their comparison to outcomes from a rat model of experimentally induced breast cancer.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Body Weight; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Flavonoids; Freeze Drying; Fruit; Humans; Hydroxybenzoates; Inhibitory Concentration 50; Malus; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytotherapy; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
N-methyl-N-nitrosourea-induced retinal degeneration in mice is independent of the p53 gene.
Topics: Animals; Body Weight; Cell Count; Female; Methylnitrosourea; Mice; Mice, Inbred C57BL; Photoreceptor Cells, Vertebrate; Retina; Retinal Degeneration; Tumor Suppressor Protein p53 | 2009 |
Vitamin D3 affects expression of thyroid hormone receptor alpha and deiodinase activity in liver of MNU-treated Sprague-Dawley rats.
Topics: Animals; Body Weight; Breast Neoplasms; Calcitriol; Cholecalciferol; DNA; Female; Gene Expression Regulation; Iodide Peroxidase; Liver; Methylnitrosourea; Organ Size; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thyroid Hormone Receptors alpha | 2009 |
Methylnitrosourea induces neural progenitor cell apoptosis and microcephaly in mouse embryos.
Topics: Animals; Apoptosis; Body Weight; Brain; Cell Count; Cell Differentiation; Cell Movement; Embryo, Mammalian; Female; Male; Methylnitrosourea; Mice; Mice, Inbred ICR; Microcephaly; Neurons; Organ Size; Pregnancy; Stem Cells; Telencephalon | 2010 |
Chemopreventive effects of zinc on prostate carcinogenesis induced by N-methyl-N-nitrosourea and testosterone in adult male Sprague-Dawley rats.
Topics: Acid Phosphatase; Animals; Anticarcinogenic Agents; bcl-X Protein; Body Weight; Lipid Peroxidation; Male; Methylnitrosourea; Organ Size; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Testosterone; Tumor Suppressor Protein p53; Zinc | 2011 |
Hypothalamic cocaine- and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary carcinogenesis.
Topics: Animals; Anorexia; Antibody Specificity; Blood Glucose; Blood Proteins; Body Weight; Cachexia; Carcinogens; Cholesterol; Eating; Feeding Behavior; Female; Hypothalamus; Immunohistochemistry; Infusions, Intraventricular; Mammary Neoplasms, Experimental; Methylnitrosourea; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Triglycerides | 2010 |
Breast tumors induced by N-methyl-N-nitrosourea are damaging to bone strength, structure, and mineralization in the absence of metastasis in rats.
Topics: Adenocarcinoma; Animals; Body Weight; Bone and Bones; Bone Density; Bone Diseases; Calcification, Physiologic; Diaphyses; Epiphyses; Female; Femur; Mammary Neoplasms, Experimental; Mechanical Phenomena; Methylnitrosourea; Neoplasm Metastasis; Rats; Rats, Sprague-Dawley | 2011 |
Organ differences in the impact of p27(kip1) deficiency on carcinogenesis induced by N-methyl-N-nitrosourea.
Topics: Adenocarcinoma; Alkylating Agents; Animals; Antimetabolites; Body Weight; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p27; Genotype; Immunohistochemistry; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Knockout; Neoplasms; Organ Size; Organ Specificity | 2013 |
Effects of body weight gain reduction resulting from chemopreventive agent treatment on mammary gland morphology.
Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Northern; Body Weight; Diet, Reducing; Disease Models, Animal; Estradiol; Female; Fenretinide; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley | 2002 |
A noncarcinogenic small dose of n-methylnitrosourea enhances colon tumorigenesis in F344 rats.
Topics: Administration, Rectal; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Female; Methylnitrosourea; Neoplasm Invasiveness; Rats; Rats, Inbred F344 | 2003 |
Dietary folate deficiency suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats.
Topics: Adenocarcinoma; Adenoma; Alkylating Agents; Animals; Body Weight; Diet; DNA Methylation; DNA, Neoplasm; Female; Folic Acid; Folic Acid Deficiency; Incidence; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 2003 |
Mechanisms by which energy restriction inhibits rat mammary carcinogenesis: in vivo effects of corticosterone on cell cycle machinery in mammary carcinomas.
Topics: Adenocarcinoma; Animals; Blotting, Western; Body Weight; Caloric Restriction; Cell Cycle; Cell Cycle Proteins; Corticosterone; Diet; Female; Glucocorticoids; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Precipitin Tests; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptors, Estrogen; Up-Regulation | 2003 |
Thymic lymphomas in Wistar rats exposed to N-methyl-N-nitrosourea (MNU).
Topics: Animals; Body Weight; Bone Marrow; Carcinogens; Male; Methylnitrosourea; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rats; Rats, Wistar; Spleen; Thymus Neoplasms | 2003 |
Serum pyrrolidone carboxypeptidase activity in N-methyl-nitrosourea induced rat breast cancer.
Topics: Animals; Biomarkers, Tumor; Body Weight; Breast Neoplasms; Carcinogens; Female; Methylnitrosourea; Pyroglutamyl-Peptidase I; Rats; Rats, Wistar; Regression Analysis | 2003 |
9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers.
Topics: Administration, Oral; Alkylating Agents; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Chromatography, High Pressure Liquid; Diet; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Naphthalenes; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Tamoxifen; Transcription Factors | 2003 |
Prepubertal resveratrol exposure accelerates N-methyl-N-nitrosourea-induced mammary carcinoma in female Sprague-Dawley rats.
Topics: Age Factors; Alkylating Agents; Animals; Body Weight; Dose-Response Relationship, Drug; Estrous Cycle; Female; Isoflavones; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2003 |
Adrenalectomy does not block the inhibition of mammary carcinogenesis by dietary energy restriction in rats.
Topics: Adrenalectomy; Animals; Blood Glucose; Body Weight; Caloric Restriction; Female; Hormones; Incidence; Insulin-Like Growth Factor Binding Proteins; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Second Primary; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Low zinc intake suppressed N-methyl-N-nitrosourea-induced mammary tumorigenesis in Sprague-Dawley rats.
Topics: Animals; Body Weight; Carcinogens; Diet; Eating; Female; Incidence; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Weight Gain; Zinc | 2004 |
Serum oxytocinase activity is related to tumor growth parameters in N-methyl nitrosourea induced rat breast cancer.
Topics: Animals; Body Weight; Carcinogens; Cystinyl Aminopeptidase; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar | 2004 |
Lack of effects of postnatal exposure to a mixture of aryl hydrocarbon-receptor agonists on the development of methylnitrosourea-induced mammary tumors in sprague-dawley rats.
Topics: Age Factors; Alkylating Agents; Animals; Animals, Newborn; Benzofurans; Body Weight; Dibenzofurans, Polychlorinated; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Environmental Exposure; Environmental Pollutants; Estrous Cycle; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Milk; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Risk Factors | 2004 |
Genistein enhances N-nitrosomethylurea-induced rat mammary tumorigenesis.
Topics: Animals; Antineoplastic Agents; Body Weight; Carcinogens; Cell Transformation, Neoplastic; Estradiol; Estrous Cycle; Female; Genistein; Mammary Neoplasms, Animal; Methylnitrosourea; Organ Size; Phytoestrogens; Rats; Rats, Sprague-Dawley | 2006 |
High salt diets dose-dependently promote gastric chemical carcinogenesis in Helicobacter pylori-infected Mongolian gerbils associated with a shift in mucin production from glandular to surface mucous cells.
Topics: Adenocarcinoma; Amino Acid Sequence; Animal Feed; Animals; Base Sequence; Body Weight; Cell Transformation, Neoplastic; Cloning, Molecular; Conserved Sequence; Dose-Response Relationship, Drug; Gastric Mucosa; Gastritis; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Male; Methylnitrosourea; Molecular Sequence Data; Mongolia; Mucins; Sequence Alignment; Sodium Chloride; Stomach Neoplasms | 2006 |
A comparative study on the protective effects of 17beta-estradiol, biochanin A and bisphenol A on mammary gland differentiation and tumorigenesis in rats.
Topics: Animals; Animals, Newborn; Anticarcinogenic Agents; Benzhydryl Compounds; Body Weight; Cell Differentiation; Dose-Response Relationship, Drug; Estradiol; Female; Genistein; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Phenols; Rats; Rats, Sprague-Dawley | 2006 |
Diphenyl diselenide supplementation delays the development of N-nitroso-N-methylurea-induced mammary tumors.
Topics: Animals; Anticarcinogenic Agents; Ascorbic Acid; Benzene Derivatives; Biomarkers; Body Weight; Carcinogens; Comet Assay; Diet; Female; Lipid Peroxidation; Liver; Mammary Neoplasms, Animal; Methylnitrosourea; Neoplasm Proteins; Organ Size; Organoselenium Compounds; Rats; Rats, Wistar; Superoxide Dismutase | 2008 |
Protective effect of Acticoa powder, a cocoa polyphenolic extract, on prostate carcinogenesis in Wistar-Unilever rats.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Body Weight; Cacao; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Models, Animal; Flavonoids; Male; Methylnitrosourea; Phenols; Plant Extracts; Polyphenols; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone Propionate | 2008 |
Preventive effects of letrozole in the model of premenopausal mammary carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Drug Screening Assays, Antitumor; Female; Letrozole; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Nitriles; Rats; Rats, Sprague-Dawley; Triazoles | 2008 |
Reduced methylation-induced mutagenesis in rat splenocytes in vivo by sub-chronic low dose exposure to N-metyl-N-nitrosourea.
Topics: Alkylating Agents; Animals; Body Weight; Dose-Response Relationship, Drug; Male; Methylation; Methylnitrosourea; Mutagenesis; Rats; Rats, Wistar; Spleen; Time Factors | 2008 |
Tumor specific reactivity during development of N-methyl-N-nitrosourea-induced rat colon cancer.
Topics: Animals; Body Weight; Colonic Neoplasms; Lymphocyte Culture Test, Mixed; Male; Methylnitrosourea; Nitrosourea Compounds; Probability; Rats; Rats, Inbred Strains | 1983 |
Modulation of tumor incidence and possible mechanisms of inhibition of mammary carcinogenesis by dietary antioxidants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antioxidants; Body Weight; Diet; Dietary Fats; Drug Interactions; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Oxidoreductases; Rats; Rats, Inbred Strains | 1983 |
Teratogenic effects of methylnitrosourea on pregnant mice before implantation.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Embryonic Development; Female; Fetal Death; Fetus; Gestational Age; Methylnitrosourea; Mice; Mice, Inbred ICR; Nitrosourea Compounds; Pregnancy | 1984 |
Effect of piroxicam on primary intestinal tumors induced in rats by N-methylnitrosourea.
Topics: Animals; Body Weight; Diet; Intestinal Neoplasms; Male; Methylnitrosourea; Piroxicam; Rats; Rats, Inbred Strains; Thiazines | 1984 |
Influence of the alkyllysophospholipid ET-18-OCH3 on methylnitrosourea-induced rat mammary carcinomas.
Topics: Animals; Antineoplastic Agents; Body Weight; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Lysophosphatidylcholines; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Phospholipid Ethers; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Promotion of N-methyl-N-nitrosourea-induced thyroid tumors by iodine deficiency in F344/NCr rats.
Topics: Animals; Body Weight; Iodine; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Organ Size; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroid Neoplasms | 1984 |
Comparison of the effect of butylated hydroxytoluene on N-nitrosomethylurea and 7,12-dimethylbenz[a]-anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Butylated Hydroxytoluene; Diet; Drug Interactions; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains | 1981 |
Inhibition of 1-methyl-1-nitrosourea-induced mammary carcinogenesis in the rat by the retinoid axerophthene.
Topics: Animals; Body Weight; Diet; Diterpenes; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Time Factors; Vitamin A | 1980 |
Effect of combined selenium and retinyl acetate treatment on mammary carcinogenesis.
Topics: Analysis of Variance; Animals; Body Weight; Diet; Diterpenes; Drug Synergism; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Pregnancy; Rats; Retinyl Esters; Selenium; Time Factors; Vitamin A | 1981 |
Syncarcinogenic action of saccharin or sodium cyclamate in the induction of bladder tumours in MNU-pretreated rats.
Topics: Animals; Body Weight; Carcinogens; Cyclamates; Drug Synergism; Eating; Female; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Saccharin; Urinary Bladder Neoplasms; Urologic Neoplasms | 1980 |
The effect of single dose N-methyl-N-nitrosourea on bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide in rats.
Topics: Animals; Body Weight; Carcinoma, Papillary; Carcinoma, Transitional Cell; FANFT; Female; Hyperplasia; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Organ Size; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms | 1981 |
Ortho-toluene sulphonamide and saccharin in the promotion of bladder cancer in the rat.
Topics: Animals; Body Weight; Drinking; Eating; Female; Kidney; Methylnitrosourea; Neoplasms, Experimental; Organ Size; Rats; Saccharin; Sulfonamides; Toluene; Tosyl Compounds; Urinary Bladder; Urinary Bladder Neoplasms | 1980 |
Elevated serum growth hormone accelerates gastric tumorigenesis in F344 rats after treatment with N-methyl-N-nitrosourea in their drinking water.
Topics: Animals; Body Weight; Carcinogens; Drinking; Growth Hormone; Iodine Radioisotopes; Male; Methylnitrosourea; Neoplasm Transplantation; Organ Size; Pituitary Neoplasms; Rats; Rats, Inbred F344; Stomach Neoplasms; Thyroidectomy; Time Factors | 1995 |
Colon cancer prevention with a small amount of dietary perilla oil high in alpha-linolenic acid in an animal model.
Topics: alpha-Linolenic Acid; Animals; Body Weight; Cholesterol; Colon; Colonic Neoplasms; Dietary Fats; Disease Models, Animal; Eating; Fatty Acids; Female; Intestinal Mucosa; Linoleic Acids; Lipids; Methylnitrosourea; Phospholipids; Plant Oils; Rats; Rats, Inbred F344; Safflower Oil; Time Factors; Triglycerides | 1994 |
Potent promoting activity of dimethylitaconate on gastric carcinogenesis induced by N-methylnitrosourea.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Cell Division; Drug Synergism; Enzyme Induction; Hyperplasia; Male; Methylnitrosourea; Rats; Rats, Inbred F344; Stomach Neoplasms; Succinates | 1994 |
Synergistic enhancement of small and large intestinal carcinogenesis by combined treatment of rats with five heterocyclic amines in a medium-term multi-organ bioassay.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Diethylnitrosamine; Dimethylhydrazines; Dose-Response Relationship, Drug; Drug Synergism; Imidazoles; Intestinal Neoplasms; Male; Methylnitrosourea; Nitrosamines; Organ Size; Rats; Rats, Inbred F344 | 1994 |
Pharmacokinetic behavior and antineoplastic activity of liposomal hexadecylphosphocholine.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Chromatography, High Pressure Liquid; Drug Carriers; Female; Half-Life; Injections, Intravenous; Liposomes; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1994 |
Inhibition of mammary tumors by pretreatment with 17 beta-estradiol in F344 rats induced with N-methyl-N-nitrosourea.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Rats; Rats, Inbred F344 | 1994 |
Effects of sodium nitrite and catechol, 3-methoxycatechol, or butylated hydroxyanisole in combination in a rat multiorgan carcinogenesis model.
Topics: Animals; Antioxidants; Body Weight; Butylated Hydroxyanisole; Carcinoma in Situ; Carcinoma, Squamous Cell; Catechols; Cocarcinogenesis; Dimethylhydrazines; Disease Models, Animal; Drug Interactions; Eating; Epithelium; Hyperplasia; Liver; Male; Methylnitrosourea; Neoplasms, Experimental; Organ Size; Rats; Rats, Inbred F344; Sodium Nitrite; Stomach; Stomach Neoplasms | 1993 |
Reduction of aberrant crypt foci induced in rat colon with azoxymethane or methylnitrosourea by feeding cholic acid.
Topics: Analysis of Variance; Animals; Azoxymethane; Body Weight; Cell Division; Cholic Acid; Cholic Acids; Colonic Neoplasms; Intestinal Mucosa; Male; Methylnitrosourea; Precancerous Conditions; Random Allocation; Rats; Rats, Sprague-Dawley | 1993 |
Effects of X-irradiation on N-methyl-N-nitrosourea-induced multi-organ carcinogenesis in rats.
Topics: Adenocarcinoma; Animals; Body Weight; Digestive System Neoplasms; Female; Kidney Neoplasms; Male; Methylnitrosourea; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Organ Size; Rats; Rats, Inbred ACI; Sex Characteristics; Uterine Neoplasms; X-Rays | 1993 |
No enhancing effects of calcium/magnesium salts of L-glutamate and L-ascorbate on tumor development in a rat medium-term multiorgan carcinogenesis bioassay.
Topics: Animals; Ascorbic Acid; Body Weight; Carcinogens; Diethylnitrosamine; Glutamates; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Organ Size; Rats; Rats, Inbred F344 | 1993 |
Carcinogenic potential of some pesticides in a medium-term multi-organ bioassay in rats.
Topics: Animals; Body Weight; Captan; Carcinogenicity Tests; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Liver; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Models, Biological; Nitrosamines; Organ Size; Pesticides; Precancerous Conditions; Rats; Rats, Inbred F344; Zineb | 1993 |
Promotion by dichloroacetic acid and trichloroacetic acid of N-methyl-N-nitrosourea-initiated cancer in the liver of female B6C3F1 mice.
Topics: Animals; Body Weight; Carcinogens; Cocarcinogenesis; Dichloroacetic Acid; Drug Synergism; Eosine Yellowish-(YS); Female; Hematoxylin; Liver Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Staining and Labeling; Trichloroacetic Acid | 1996 |
Cyclic food restriction alters substrate utilization and abolishes protection from mammary carcinogenesis female rats.
Topics: Adipose Tissue; Animals; Body Weight; Calorimetry, Indirect; Carcinogens; Diet; Eating; Energy Metabolism; Fatty Acids; Female; Glucose; Incidence; Lipid Metabolism; Mammary Neoplasms, Experimental; Methylnitrosourea; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Bile Acids and Salts; Body Weight; Cholesterol; Colonic Neoplasms; Drinking; Eating; Enzyme Inhibitors; Feces; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Methylnitrosourea; Pravastatin; Rats; Rats, Inbred F344; Sterols | 1996 |
Combination of melatonin and tamoxifen as a chemoprophylaxis against N-nitroso-N-methylurea-induced rat mammary tumors.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen | 1997 |
Promotion by mixtures of dichloroacetic acid and trichloroacetic acid of N-methyl-N-nitrosourea-initiated cancer in the liver of female B6C3F1 mice.
Topics: Animals; Body Weight; Carcinogens; Cocarcinogenesis; Dichloroacetic Acid; Drug Combinations; Female; Glutathione Transferase; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Methylnitrosourea; Mice; Organ Size; Time Factors; Trichloroacetic Acid; Water Pollutants, Chemical | 1997 |
Fasting during promotion, but not during initiation, enhances the growth of methylnitrosourea-induced mammary tumours.
Topics: Adenocarcinoma; Animals; Body Weight; Fasting; Female; Kidney Neoplasms; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovarian Neoplasms; Rats; Rats, Sprague-Dawley; Uterine Neoplasms | 1997 |
Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEN, MNU and DMH.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Carotenoids; Chemoprevention; Colonic Neoplasms; Diethylnitrosamine; Female; Liver Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Lycopene; Male; Methylnitrosourea; Mice; Organ Size | 1997 |
Insulin does not promote rat mammary carcinogenesis.
Topics: Animals; Blood Glucose; Body Weight; Carcinogens; Female; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 1998 |
N-methyl-N-nitrosourea concentration-dependent, rather than total intake-dependent, induction of adenocarcinomas in the glandular stomach of BALB/c mice.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Drug Administration Schedule; Male; Methylnitrosourea; Mice; Mice, Inbred BALB C; Stomach Neoplasms; Survival Rate | 1998 |
Dietary lignin, and insoluble fiber, enhance uterine cancer but did not influence mammary cancer induced by N-methyl-N-nitrosourea in rats.
Topics: Adenocarcinoma; Animals; Body Weight; Brassica; Carcinoma, Squamous Cell; Dietary Fiber; Eating; Endometrial Neoplasms; Female; Lignin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Uterine Cervical Neoplasms | 1998 |
Chemoprevention of N-nitroso-N-methylurea-induced rat mammary cancer by miso and tamoxifen, alone and in combination.
Topics: Animals; Body Weight; Drug Therapy, Combination; Female; Glycine max; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen; Time Factors | 1998 |
Influence of N-methyl-N-nitrosourea, testosterone, and N-(4-hydroxyphenyl)-all-trans-retinamide on prostate cancer induction in Wistar-Unilever rats.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Cocarcinogenesis; Fenretinide; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone | 1998 |
Quercetin enhances pretumorous lesions in the NMU model of rat pancreatic carcinogenesis.
Topics: Animals; Body Weight; Carcinogens; Cocarcinogenesis; Female; Male; Methylnitrosourea; Organ Size; Pancreatic Neoplasms; Precancerous Conditions; Pregnancy; Quercetin; Rats; Rats, Wistar | 1998 |
Chemopreventive effects of the aromatase inhibitor vorozole (R 83842) in the methylnitrosourea-induced mammary cancer model.
Topics: Animals; Antineoplastic Agents; Aromatase Inhibitors; Body Weight; Carcinogens; Drug Administration Schedule; Drug Screening Assays, Antitumor; Estradiol; Estrus; Female; Genes, ras; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Testosterone; Triazoles | 1998 |
Effects of low dose catechol on glandular stomach carcinogenesis in BALB/c mice initiated with N-methyl-N-nitrosourea.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Catechols; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Humans; Immunohistochemistry; Male; Methylnitrosourea; Mice; Mice, Inbred BALB C; Pepsinogen A; Stomach Neoplasms | 1999 |
Tumor-promoting activities of hydroquinone and 1,1-dimethylhydrazine after initiation of newborn mice with 1-methyl-1-nitrosourea.
Topics: Adenoma; Animals; Animals, Newborn; Body Weight; Carcinogens; Carcinoma; Dimethylhydrazines; Female; Hydroquinones; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Methylnitrosourea; Mice; Mice, Inbred ICR; Mutagens; Organ Size | 1999 |
Modification of murine adult haemopoiesis and response to methyl nitrosourea following exposure to radiation at different developmental stages.
Topics: Age Factors; Animals; Body Weight; Bone Marrow Neoplasms; Carcinogens; Cell Count; Dose-Response Relationship, Radiation; Female; Gamma Rays; Hematopoiesis; Litter Size; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Neoplasms, Radiation-Induced; Stem Cells | 2000 |
Lymphoproliferative response and T lymphocyte subsets in a medium-term multi-organ bioassay for carcinogenesis in Wistar rats.
Topics: 1,2-Dimethylhydrazine; 2-Acetylaminofluorene; Alkylating Agents; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Carcinogens; Concanavalin A; Diethylnitrosamine; Flow Cytometry; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Rats; Rats, Wistar; Spleen; T-Lymphocyte Subsets; Tissue Distribution | 2000 |
Effect of dietary fatty acids on tumorigenesis of colon cancer induced by methyl nitrosourea in rats.
Topics: Alkaline Phosphatase; Animals; Body Weight; Cell Cycle; Cell Transformation, Neoplastic; Colonic Neoplasms; Diet; Dietary Fats; Dinoprostone; Fatty Acids; Intestinal Mucosa; Male; Membrane Fluidity; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Testis | 2000 |
Plasma insulin-like growth factor I levels in rats are reduced by dietary supplementation of flaxseed or its lignan secoisolariciresinol diglycoside.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Butylene Glycols; Carcinogens; Dietary Supplements; Eating; Female; Flax; Glucosides; Insulin-Like Growth Factor I; Lignans; Mammary Glands, Animal; Methylnitrosourea; Organ Size; Rats; Rats, Sprague-Dawley | 2000 |
Preventive effects of Juzen-taiho-to on N-methyl-N-nitrosourea and estradiol-17beta-induced endometrial carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Blotting, Southern; Body Weight; Carcinogens; Drugs, Chinese Herbal; Endometrial Neoplasms; Estradiol; Female; Immunohistochemistry; Methylnitrosourea; Mice; Mice, Inbred ICR; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Uterus | 2001 |
Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid.
Topics: Adenocarcinoma; Alitretinoin; Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Carcinogens; Drug Synergism; Drug Therapy, Combination; Estradiol; Estrogen Receptor alpha; Female; Free Radical Scavengers; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Tretinoin; Uterus | 2001 |
Twenty-six-week carcinogenicity study of sulfamethoxazole in CB6F1-Tg-rasH2 mice.
Topics: Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Female; Genes, ras; Harderian Gland; Humans; Hyperplasia; Lung Neoplasms; Male; Methylnitrosourea; Mice; Mice, Transgenic; Neoplasms, Experimental; Splenic Neoplasms; Sulfamethoxazole; Thyroid Gland | 2001 |
Post-initiation treatment of Indole-3-carbinol did not suppress N-methyl-N-nitrosourea induced mammary carcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Female; Indoles; Mammary Neoplasms, Animal; Methylnitrosourea; Organ Size; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Preventive effects of raloxifene and melatonin in N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Drinking; Eating; Female; Kinetics; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Organ Size; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Uterus | 2001 |
Synergistic tumor promoter effects of estrone and progesterone in methylnitrosourea-induced rat mammary cancer.
Topics: Alkylating Agents; Animals; Body Weight; Drug Synergism; Estrone; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Ovariectomy; Pituitary Gland; Progesterone; Rats; Rats, Sprague-Dawley; Time Factors; Uterus | 2002 |
Influence of dietary fat on the induction of mammary tumors by N-nitrosomethylurea: associated hormone changes and differences between Sprague-Dawley and F344 rats.
Topics: Adenocarcinoma; Animals; Body Weight; Dietary Fats; Estrogens; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Pregnancy; Prolactin; Rats; Rats, Inbred F344; Species Specificity | 1977 |
Marked enhancement of rat urinary bladder carcinogenesis by heat-killed Escherichia coli.
Topics: Administration, Intravesical; Animals; Body Weight; Buffers; Cell Wall; Escherichia coli; Hot Temperature; Hyperplasia; Male; Methylnitrosourea; Neoplasm Transplantation; Phosphates; Rats; Rats, Inbred F344; Sodium Chloride; Thymidine; Transplantation, Heterotopic; Tritium; Urinary Bladder; Urinary Bladder Neoplasms; Urine | 1992 |
Investigations of droloxifene and other hormone manipulations on N-nitrosomethylurea-induced rat mammary tumours. 1. Influence on tumour growth.
Topics: Animals; Antineoplastic Agents; Body Weight; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Sprague-Dawley; Tamoxifen | 1992 |
Influence of reducing luxury calories in the treatment of experimental mammary carcinoma.
Topics: Animals; Body Weight; Dietary Fats; Energy Intake; Estradiol; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Recurrence; Testosterone | 1992 |
Inhibitory effect of dietary perilla oil rich in the n-3 polyunsaturated fatty acid alpha-linolenic acid on colon carcinogenesis in rats.
Topics: alpha-Linolenic Acid; Animals; Body Weight; Colonic Neoplasms; Dietary Fats; Dinoprostone; Fatty Acids; Feeding Behavior; Intestinal Mucosa; Linolenic Acids; Methylnitrosourea; Oils; Ornithine Decarboxylase; Rats; Rats, Inbred F344; Safflower Oil | 1991 |
Modulation of N-nitrosomethylurea-induced mammary tumor promotion by dietary fiber and fat.
Topics: Animals; Body Weight; Charcoal; Dextrans; Dietary Fats; Dietary Fiber; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogens; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Radioimmunoassay; Rats; Rats, Inbred F344; Tritium | 1991 |
Dietary soybean isolate and methionine supplementation affect mammary tumor progression in rats.
Topics: Animals; Body Weight; Carcinogens; Caseins; Diet; Female; Glycine max; Injections, Intravenous; Mammary Neoplasms, Experimental; Methionine; Methylnitrosourea; Rats; Rats, Inbred Strains | 1991 |
Rapid induction of endometrial carcinoma in ICR mice treated with N-methyl-N-nitrosourea and 17 beta-estradiol.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinoma, Squamous Cell; Disease Models, Animal; Endometrial Neoplasms; Estradiol; Female; Methylnitrosourea; Mice; Mice, Inbred ICR; Organ Size; Ovarian Cysts; Ovary; Uterine Cervical Neoplasms; Uterine Neoplasms; Uterus | 1991 |
Early neurobehavioral disorders in the micrencephalic offspring induced by prenatal treatment with N-methyl-N-nitrosourea or methylazoxymethanol in the rat.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Female; Locomotion; Male; Methylazoxymethanol Acetate; Methylnitrosourea; Microcephaly; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Rodent Diseases; Swimming | 1991 |
Induction of invasive carcinomas of the seminal vesicles and coagulating glands of F344 rats by administration of N-methylnitrosourea or N-nitrosobis(2-oxopropyl)amine and followed by testosterone propionate with or without high-fat diet.
Topics: Animals; Body Weight; Bulbourethral Glands; Colonic Neoplasms; Dietary Fats; Drug Synergism; Genital Neoplasms, Male; Kidney Neoplasms; Lung Neoplasms; Male; Methylnitrosourea; Nitrosamines; Organ Size; Prostate; Prostatic Neoplasms; Radioimmunoassay; Rats; Rats, Inbred F344; Seminal Vesicles; Testosterone; Urethral Neoplasms; Urinary Bladder Neoplasms | 1991 |
Effect of deficiencies of selenium and vitamin E alone or in combination on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea.
Topics: Analysis of Variance; Animals; Antioxidants; Body Weight; Diet; Dose-Response Relationship, Drug; Drug Synergism; Female; Glutathione Peroxidase; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Regression Analysis; Selenium; Vitamin E Deficiency | 1991 |
Evaluation of the effect of dietary thiram on gamma-glutamyltranspeptidase activity and histopathology of pancreas of rats treated with nitrosomethylurea.
Topics: Administration, Oral; Body Weight; Diet; Enzyme Induction; gamma-Glutamyltransferase; Inactivation, Metabolic; Methylnitrosourea; Organ Size; Pancreas; Thiram | 1990 |
Effect of dietary iron deficiency or excess on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea.
Topics: Animals; Body Weight; Female; Iron; Iron Deficiencies; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains | 1991 |
Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model.
Topics: Allyl Compounds; Animals; Body Weight; Diethylnitrosamine; Disease Models, Animal; Germanium; Indoles; Kidney; Liver; Liver Neoplasms, Experimental; Lung; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Organ Size; Rats; Rats, Inbred F344; Sulfides | 1991 |
Effect of dietary calorie and fat restriction on mammary tumor growth and hepatic as well as tumor glutathione in rats.
Topics: Animals; Body Weight; Dietary Fats; Energy Intake; Female; Glutathione; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1991 |
Induction of dorsolateral prostate adenocarcinomas and other accessory sex gland lesions in male Wistar rats by a single administration of N-methyl-N-nitrosourea, 7,12-dimethylbenz(a)anthracene, and 3,2'-dimethyl-4-aminobiphenyl after sequential treatment
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Aminobiphenyl Compounds; Animals; Body Weight; Cyproterone; Cyproterone Acetate; Genitalia, Male; Male; Methylnitrosourea; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Sarcoma, Experimental; Survival Analysis; Testosterone | 1990 |
The effects of methylnitrosourea (MNU) on natural killer (NK) cell cytotoxicity and cytokine production in rats.
Topics: Animals; Biological Factors; Body Weight; Cytokines; Dinoprostone; Immunosuppressive Agents; Interleukin-2; Kidney; Killer Cells, Natural; Leukocyte Count; Male; Methylnitrosourea; Organ Size; Rats; Rats, Inbred Strains; Spleen; Thymus Gland; Time Factors | 1990 |
Effects of sex difference, gonadectomy, and estrogen on N-methyl-N-nitrosourea induced rat thyroid tumors.
Topics: Animals; Body Weight; Castration; Disease Models, Animal; Estradiol; Female; Gonadal Steroid Hormones; Male; Methylnitrosourea; Neoplasms, Experimental; Organ Size; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sex Factors; Thyroid Gland; Thyroid Neoplasms; Thyrotropin | 1990 |
1 Alpha-hydroxyvitamin D3 suppresses colonic tumorigenesis induced by repetitive intrarectal injection of N-methyl-N-nitrosourea in rats.
Topics: Adenoma; Administration, Rectal; Animals; Body Weight; Colonic Neoplasms; Female; Hydroxycholecalciferols; Incidence; Methylnitrosourea; Rats; Rats, Inbred F344 | 1990 |
Reduction in mammary tumorigenesis in the rat by cabbage and cabbage residue.
Topics: Animals; Body Weight; Brassica; Diet; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Modifying effects of simultaneous treatment with butylated hydroxyanisole (BHA) on rat tumor induction by 3,2'-dimethyl-4-aminobiphenyl, 2,2'-dihydroxy-di-n-propylnitrosamine and N-methylnitrosourea.
Topics: Aminobiphenyl Compounds; Animals; Body Weight; Butylated Hydroxyanisole; Carcinogens; Hyperplasia; Kidney; Liver; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Stomach Neoplasms; Tongue Neoplasms; Urinary Bladder Neoplasms | 1989 |
Inhibition of methylnitrosourea-induced large bowel cancer development in rats by sarcophytol A, a product from a marine soft coral Sarcophyton glaucum.
Topics: Animals; Antineoplastic Agents; Body Weight; Colonic Neoplasms; Diterpenes; Female; Methylnitrosourea; Mollusca; Rats; Rats, Inbred F344; Reference Values | 1989 |
Strong promoting activity by uracil on urinary bladder carcinogenesis and a possible inhibitory effect on thyroid tumorigenesis in rats initiated with N-methyl-N-nitrosourea.
Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Carcinoma, Transitional Cell; Male; Methylnitrosourea; Organ Size; Papilloma; Rats; Rats, Inbred F344; Reference Values; Thyroid Neoplasms; Uracil; Urinary Bladder Neoplasms | 1989 |
Retinoid-tamoxifen interaction in mammary cancer chemoprevention.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Dose-Response Relationship, Drug; Drug Synergism; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen; Tretinoin | 1986 |
Promoting effect of 5 beta-chol-3-en-24-oic acid on N-methyl-N-nitrosourea-induced colonic tumorigenesis in rats.
Topics: Animals; Bile Acids and Salts; Body Weight; Carcinogens; Cholic Acids; Colon; Colonic Neoplasms; Feces; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Time Factors | 1987 |
Role of polyamines in the growth of hormone-responsive experimental breast cancer in vivo.
Topics: Animals; Biogenic Polyamines; Body Weight; Dose-Response Relationship, Drug; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Putrescine; Rats; Rats, Inbred Strains | 1988 |
DNA strand breaks in embryonic mouse limbs exposed to methylnitrosourea.
Topics: Animals; Body Weight; DNA Damage; Extremities; Female; Methylnitrosourea; Mice; Mice, Inbred ICR; Pregnancy; Teratogens | 1988 |
Influence of dietary fat, caloric restriction, and voluntary exercise on N-nitrosomethylurea-induced mammary tumorigenesis in rats.
Topics: Animals; Body Composition; Body Weight; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Physical Exertion; Rats; Rats, Inbred F344 | 1988 |
Genotype-specific reduction in methyl nitrosourea (MNU) induced sister chromatid exchanges (SCE) in vivo during aging.
Topics: Aging; Animals; Body Weight; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Genotype; Methylnitrosourea; Mice; Mice, Inbred Strains; Sister Chromatid Exchange | 1988 |
Dietary fat and mammary cancer. I. Promoting effects of different dietary fats on N-nitrosomethylurea-induced rat mammary tumorigenesis.
Topics: Animals; Body Weight; Cocarcinogenesis; Dietary Fats; Fatty Acids; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Oils; Rats; Rats, Inbred F344; Statistics as Topic; Time Factors | 1986 |
Comparison between the effects of dietary fat level and of calorie intake on methylnitrosourea-induced mammary carcinogenesis in female SD rats.
Topics: Animals; Body Weight; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains | 1987 |
The influence of different levels of dietary fat on the incidence and growth of MNU-induced mammary carcinoma in rats.
Topics: Animals; Body Weight; Cholesterol; Dietary Fats; Female; Lipoproteins; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Triglycerides | 1987 |
Effects of vitamin A and E supplementation to diets containing two different fat levels on methylnitrosourea-induced mammary carcinogenesis in female SD-rats.
Topics: Animals; Body Weight; Dietary Fats; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Vitamin A; Vitamin E | 1987 |
Dietary protein, enhancement of N-nitrosomethylurea-induced mammary carcinogenesis, and their effect on hormone regulation in rats.
Topics: alpha-Methyltyrosine; Animals; Body Weight; Dietary Fats; Dietary Proteins; Energy Intake; Estrus; Female; Growth Hormone; Mammary Neoplasms, Experimental; Methylnitrosourea; Methyltyrosines; Prolactin; Rats | 1986 |
Comparison of the acute toxicity of N-nitrosocimetidine with three structurally related carcinogens in the rat.
Topics: Administration, Oral; Animals; Body Weight; Cimetidine; Female; Methylnitronitrosoguanidine; Methylnitrosourea; Nitrosomethylurethane; Rats; Rats, Inbred F344; Urethane | 1986 |
Effects of molybdenum and tungsten on mammary carcinogenesis in SD rats.
Topics: Animals; Body Weight; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Molybdenum; Pregnancy; Rats; Rats, Inbred Strains; Tungsten | 1985 |
Tumorigenic effects of direct- and indirect-acting chemical carcinogens in rats on a restricted diet.
Topics: Animals; Body Weight; Colonic Neoplasms; Diet; Intestinal Neoplasms; Intestine, Large; Intestine, Small; Male; Methylazoxymethanol Acetate; Methylnitrosourea; Rats; Rats, Inbred Strains | 1985 |
N-Nitroso-N-methylurea initiation in multiple tissues for organ-specific tumor promotion in rats by phenobarbital.
Topics: Animals; Body Weight; Carcinogens; Female; Liver; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Organ Size; Organ Specificity; Phenobarbital; Rats; Rats, Inbred F344; Sex Factors; Thyroid Neoplasms | 1985 |
Polyamines and estrogen control of growth of the NMU-induced rat mammary tumor.
Topics: Animals; Body Weight; Cell Division; Dose-Response Relationship, Drug; Drug Interactions; Eflornithine; Estradiol; Estrogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mitoguazone; Nitrosourea Compounds; Ornithine; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred Strains; Tamoxifen | 1985 |
Dietary iodine deficiency as a tumor promoter and carcinogen in male F344/NCr rats.
Topics: Animals; Body Weight; Carcinoma; Iodine; Male; Methylnitrosourea; Neoplasm Transplantation; Organ Size; Pituitary Neoplasms; Rats; Thyroid Neoplasms | 1986 |
The effects of dietary butylated hydroxytoluene on liver and colon tumor development in mice.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Butylated Hydroxytoluene; Carcinogens; Colonic Neoplasms; Diet; Dimethylhydrazines; Female; Gastrointestinal Neoplasms; Liver Neoplasms; Male; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Multiple Primary; Time Factors | 1986 |