Compounds > methylnitrosourea
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methylnitrosourea and Bladder Cancer

methylnitrosourea has been researched along with Bladder Cancer in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-199064 (56.14)18.7374
1990's37 (32.46)18.2507
2000's7 (6.14)29.6817
2010's5 (4.39)24.3611
2020's1 (0.88)2.80

Authors

AuthorsStudies
Capibaribe, DM; Denardi, F; Kiehl, IGA; Reis, LO; Salustiano, ACC1
Billis, A; Camargo, JA; Ferrari, KL; Passos, GR; Reis, LO; Saad, MJA1
Bishai, WR; Bivalacqua, TJ; Joice, G; Kates, M; Liu, X; McConkey, DJ; Singh, AK; Sopko, NA; Yoshida, T1
Cheng, Y; Jiang, Y; Li, J; Qu, W; Sun, Y; Wang, Z; Xu, Y; Zhao, H; Zou, T1
Billis, A; Fávaro, WJ; Ferrari, K; Reis, LO; Rocha, GZ; Zamuner, M1
Boring, D; Grubbs, CJ; Juliana, MM; Kopelovich, L; Lubet, RA; Patlolla, J; Rao, CV; Steele, VE; Zhang, Y1
Han, X; Li, B; Li, W; Liu, D; Pan, F; Pang, Z; Shi, Y; Zhang, Q1
Barder, T; Getzenberg, RH; Konety, BR; Myers, J; Van Le, TS1
Chang, HC; Chen, J; Cui, L; Dai, G; Pan, H; Sheng, H; Shi, Y; Song, L; Wang, S; Wang, X1
Ding, H; Feugang, JM; Qian, L; Shao, P; Wang, X; Wu, S; Yang, J; Zhou, J; Zou, C1
Barbisan, LF; Bidinotto, LT; Rocha, NS; Salvadori, DM; Spinardi-Barbisan, AL1
Hodges, GM; Nathrath, WJ; Summerhayes, IC; Trejdosiewicz, LK; Wilson, PD1
McCallum, L; Nissenkorn, I; Soloway, MS1
Bodenstab, W; Kaufman, J; Parsons, CL1
Catalona, WJ; Kelley, DR; Oakley, DM; Ratliff, TL; Shapiro, A1
Sapritskiĭ, AV1
Numata, I; Oyasu, R; Ozono, S1
Akagi, A; Izumi, K; Jacobs, JB; Miyata, Y; Otsuka, H; Oyasu, R; Ozono, S; Shibata, M; Togei, K1
Fukushima, S; Imaida, K; Ito, N; Masui, T; Ogiso, T; Shirai, T1
Billington, S; Smith, JH; Smith, MR; Stemplewski, HE; Tipton, PW; Wallace, DM1
Hicks, RM2
Fukushima, S; Imaida, K; Ito, N; Shirai, T; Tatematsu, M; Tsuda, H1
Beagley, K; Goodall, CM; Horne, L; Noronha, RF1
Hicks, RM; Severs, NJ; Tudor, RJ1
Babaya, K; Hirao, Y; Iwai, A; Matsuki, H; Nakatsuji, F; Okajima, E; Samma, S; Tabata, S; Uemura, H1
Babaya, K; Chmiel, JS; Izumi, K; Miyata, Y; Morikawa, A; Oyasu, R; Ozono, S1
Fukushima, S; Imaida, K; Ito, N; Kurata, Y; Tsuda, H1
Babaya, K; Morikawa, A; Oyasu, R; Ozono, S1
Bonneville, MA; Caruthers, JM1
Barnes, SH; Hicks, RM; Severs, NJ; Wright, R1
Allhoff, EP; Chapman, CM; Hagen, IK; Lin, CW; Lin, JC; Mei, H; Proppe, KH; Prout, GR1
Althoff, J; Brune, H; Deutsch-Wenzel, R; Green, U; Schneider, P1
Grossman, HB; Lesser, ML; Sonda, LP1
Babaya, K; Miyata, Y; Oyasu, R1
Kakizoe, T; Kawachi, T; Komatsu, H; Niijima, T; Sugimura, T1
Chowaniec, J; Grasso, P; Hicks, RM; Hooson, J1
Kawai, K; Kawamata, H; Okamoto, M; Oyasu, R1
Kameyama, S; Kawai, K; Kawamata, H; Oyasu, R; Rademaker, A1
Clarke, HS; Dillehay, DL; Graham, SD; Kassabian, VS; Keane, TE; Napalkov, P; Oladele, A; Petros, JA1
Ito, N; Montesano, R; Ogawa, K; Shibata, MA; Shirai, T; Takahashi, S; Tsuda, H; Wild, CP1
Allen, RR; Gaylor, DW; Kadlubar, FF; Sheldon, WG; West, RW1
Kawai, K; Kawamata, H; Kemeyama, S; Oyasu, R; Rademaker, A1
Kameyama, S; Kawai, K; Kawamata, H; Oyasu, R; Rademaker, A; Yamamoto, M1
Kameyama, S; Kawai, K; Kawamata, H; Nan, L; Oyasu, R1
Fujimoto, K; Oyasu, R; Rademaker, A; Tanaka, Y1
Adelstein, SJ; Baranowska-Kortylewicz, J; Barclay, PD; Berman, RM; Kassis, AI; Richie, JP; Tutrone, RF; Van den Abbeele, AD1
Kawai, K; Okamoto, M; Oyasu, R; Reznikoff, CA1
Kawabe, M; Orita, SI; Ozaki, M; Shibata, MA; Shirai, T; Takahashi, S1
Hino, A; Itakura, M; Iwahana, H; Izumi, K; Kudo, E; Min, H; Yoshimoto, K1
Ahrens, H; Gabius, HJ; Kunze, E; Schulz, H1
Futakuchi, M; Hasegawa, R; Ito, N; Lijinsky, W; Mizoguchi, Y; Shirai, T; Yamaguchi, T1
Gabius, HJ; Kunze, E; Schulz, H1
Fujimoto, K; Hattori, K; Oyasu, R; Rademaker, A; Tamatani, T1
Brasic, GM; Gould, MN; Grubbs, CJ; Haag, JD; Kelloff, GJ; Lubet, RA; Newton, MA; Shepel, LA1
Göğüş, O; Ozdiler, E; Sözen, S; Yaman, O1
Elsässer-Beile, U; Freudenberg, N; Mengs, U; Ruhnau, T; Wetterauer, U1
Fukushima, S2
Hicks, RM; Hodges, GM; Spacey, GD1
Reuber, MD1
Anichkov, NM1
Hodges, GM; Wilson, PD1
Richelo, BN; Tannenbaum, M; Tannenbaum, S; Trown, PW1
Cox, R; Irving, CC; Murphy, WM1
Hirao, Y; Iwasaki, T; Matsumoto, M; Oyasu, R; Tabuchi, Y1
Pozharisskiĭ, KM1
Martino, C; Soloway, MS1
Brown, CC; Smith, JM; Sporn, MB; Springer, S; Squire, RA; Wenk, ML2
Chowaniec, J; Hicks, RM1
Balanski, RM; Khudoleĭ, VV; Vlasov, NN1
Soloway, MS; Weldon, TE1
Friedman, RD; Reese, DH; Smith, JM; Sporn, MB1
Momose, H; Oyasu, R; Rademaker, A; Wu, HH; Yamamoto, M1
Margison, GP; Masters, JR; Walker, MC1
Cohen, SM; Garland, EM; Macatee, TL; Mann, AM; Masui, T; Okamura, T; Smith, RA2
Greve, T; Kuntse, E; Veber, Zh1
Heatfield, BM; Reedy, EA; Resau, JH; Trump, BF1
Azuma, M; Momose, H; Oyasu, R; Uchida, K; Yura, Y1
Azuma, M; Debiec-Rychter, M; Oyasu, R; Wang, CY; Zukowski, K1
Bae, JH; Cho, KJ; Jang, JJ; Lee, YS1
Fukushima, S; Hirose, M; Ito, N; Kato, T; Shibata, MA; Tatematsu, M1
Iwasaki, S; Masui, T; Shirai, T; Tamano, S; Yamamoto, A1
Brendler, CB; Isaacs, JT; Squire, RA; Steinberg, GD1
Kunze, E1
Kunze, E; Ruschitzka, F; Schwalbe, K1
Brendler, CB; Ichikawa, T; Isaacs, JT; Squire, RA; Steinberg, GD1
Azuma, M; Momose, H; Oyasu, R1
Babaya, K; Fujimoto, K; Hirao, Y; Momose, H; Okajima, E; Okamoto, S; Ozono, S; Sasaki, K; Tsumatani, K; Yamaguchi, H1
Homma, Y; Oyasu, R; Ozono, S1
Bopp, BA; Kesterson, JW; Sonders, RC1
Hicks, RM; Jani, H; Knowles, MA1
Hodges, GM; Howlett, AR; Norman, JT; Spacey, GD1
Hirose, M; Ito, N; Shibata, M; Shirai, T; Tanaka, H1
Gellhar, P; Graewe, T; Kunze, E; Scherber, S; Weber, J1
Cohen, SM; Garland, EM; Mann, AM; Masui, T1
Hastrup, J; Langkilde, NC; Olsen, S; Orntoft, TF; Wolf, H1
Oyasu, R; Rinsho, K; Samma, S; Uchida, K1
Oyasu, R; Samma, S1
Imaida, K; Lee, MS; Wang, CY; Zukowski, K1
Shimamura, T1
Gassner, G; Kunze, E1
Homma, Y; Nowels, K; Oyasu, R1
Johnson, MD; Loretz, LJ; Reznikoff, CA; Swaminathan, S1
Bauer, K; Homma, Y; Oyasu, R; Ozono, S; Samma, S; Wallemark, CB1
Homma, Y; Nowels, K; Oyasu, R; Seidenfeld, J1
Delongchamp, RR; Gaylor, DW; Haskin, MG; Kadlubar, FF; Sheldon, WG; West, RW1
Chen, JJ; Gaylor, DW; Kodell, RL1
Bellnier, DA; Lin, CW; Prout, GR1
Fukushima, S; Ito, N; Tsuda, H1
Homma, Y; Numata, I; Oyasu, R; Ozono, S; Seidenfeld, J1
Berry, RJ; Hicks, RM; Jani, H; Knowles, MA1

Reviews

9 review(s) available for methylnitrosourea and Bladder Cancer

ArticleYear
Luminal plasma membrane alterations in bladder cancer.
    Investigative urology, 1980, Volume: 17, Issue:5

    Topics: Animals; Cell Membrane; Cell Membrane Permeability; Cilia; FANFT; Intercellular Junctions; Methylnitrosourea; Microvilli; Neoplasms, Experimental; Rats; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms

1980
Multistage carcinogenesis in the urinary bladder.
    British medical bulletin, 1980, Volume: 36, Issue:1

    Topics: Animals; Cricetinae; Cyclamates; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Female; Formamides; Methylnitrosourea; Neoplasms, Experimental; Rats; Saccharin; Skin Neoplasms; Urinary Bladder Calculi; Urinary Bladder Neoplasms

1980
Epithelial-stromal interactions in normal and chemical carcinogen-treated adult bladder.
    Cancer research, 1977, Volume: 37, Issue:10

    Topics: Animals; Cell Differentiation; Cell Membrane; Culture Techniques; Epithelium; Female; Mesoderm; Methylnitrosourea; Microscopy, Electron, Scanning; Microvilli; Neoplasms, Experimental; Precancerous Conditions; Rats; Urinary Bladder; Urinary Bladder Neoplasms

1977
Carcinogenicity of saccharin.
    Environmental health perspectives, 1978, Volume: 25

    Topics: Animals; Carcinogens; Diet; Female; Lung Neoplasms; Male; Methylnitrosourea; Mice; Parasitic Diseases; Rats; Saccharin; Sex Factors; Species Specificity; Tosyl Compounds; United States; United States Food and Drug Administration; Urinary Bladder Calculi; Urinary Bladder Neoplasms; Urogenital Neoplasms

1978
[Experimental replication of bladder tumors. Morphologic features of early stages of their development].
    Vestnik Akademii meditsinskikh nauk SSSR, 1979, Issue:9

    Topics: 2-Acetylaminofluorene; 2-Naphthylamine; Animals; Butylhydroxybutylnitrosamine; Cell Membrane; Cell Transformation, Neoplastic; DNA, Neoplasm; Epithelium; FANFT; Humans; Hyperplasia; Methylcholanthrene; Methylnitrosourea; Mice; Microscopy, Electron; Naphthalenes; Neoplasms, Experimental; Papilloma; Rats; Schistosoma haematobium; Species Specificity; Sulfonamides; Urinary Bladder Neoplasms

1979
[Successes of experimental oncology and problems of the study of the morphogenesis of tumors].
    Arkhiv patologii, 1975, Volume: 37, Issue:4

    Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Azoxymethane; Benzopyrenes; Brain Neoplasms; Carcinogens; Cricetinae; Dimethylhydrazines; Dogs; Esophageal Neoplasms; Ethionine; Ethylnitrosourea; Female; Hematopoietic System; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Nitrosoguanidines; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms

1975
Modification of tumor development in the urinary bladder.
    Progress in experimental tumor research, 1991, Volume: 33

    Topics: Animals; Antineoplastic Agents; Antioxidants; Butylhydroxybutylnitrosamine; Cocarcinogenesis; FANFT; Methylnitrosourea; Precancerous Conditions; Urinary Bladder Neoplasms

1991
Toxicological aspects of cyclamate and cyclohexylamine.
    Critical reviews in toxicology, 1986, Volume: 16, Issue:3

    Topics: Abnormalities, Drug-Induced; Absorption; Adrenal Glands; Animals; Bacteria; Blood; Blood Glucose; Chick Embryo; Chromosome Aberrations; Cocarcinogenesis; Cricetinae; Cyclamates; Cyclohexylamines; Digestive System; Female; Germ Cells; Heart; Humans; In Vitro Techniques; Intestines; Kidney; Lethal Dose 50; Liver; Liver Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin; Macaca mulatta; Male; Methylnitrosourea; Mice; Mutagenicity Tests; Mutagens; Mutation; Neoplasms, Experimental; Pancreas; Pregnancy; Rabbits; Rats; Rats, Inbred Strains; Reproduction; Sympathomimetics; Testis; Thyroid Gland; Tissue Distribution; Urinary Bladder Neoplasms

1986
Carcinogenicity and modification of the carcinogenic response by BHA, BHT, and other antioxidants.
    Critical reviews in toxicology, 1985, Volume: 15, Issue:2

    Topics: Animals; Anisoles; Antioxidants; Ascorbic Acid; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cocarcinogenesis; Drug Synergism; Humans; Kidney Neoplasms; Liver Neoplasms; Methylnitrosourea; Neoplasms; Species Specificity; Stomach Neoplasms; Urinary Bladder Neoplasms

1985

Trials

2 trial(s) available for methylnitrosourea and Bladder Cancer

ArticleYear
Castration immunoregulates toll-like receptor-4 in male bladder cancer.
    International urology and nephrology, 2022, Volume: 54, Issue:11

    Topics: Adjuvants, Immunologic; Administration, Intravesical; Androgens; Animals; Anticarcinogenic Agents; BCG Vaccine; Carcinogenesis; Carcinoma, Transitional Cell; Castration; Ki-67 Antigen; Male; Methylnitrosourea; Rats; Toll-Like Receptor 4; Urinary Bladder Neoplasms

2022
Urothelial susceptibility to tumor cell implantation: comparison of cauterization with N-methyl-N-nitrosourea.
    Urology, 1983, Volume: 21, Issue:2

    Topics: Animals; Carcinoma, Transitional Cell; Cautery; Clinical Trials as Topic; Epithelium; Female; Methylnitrosourea; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Random Allocation; Urinary Bladder; Urinary Bladder Neoplasms

1983

Other Studies

103 other study(ies) available for methylnitrosourea and Bladder Cancer

ArticleYear
Intravesical Immunomodulatory Imiquimod Enhances Bacillus Calmette-Guérin Downregulation of Nonmuscle-invasive Bladder Cancer.
    Clinical genitourinary cancer, 2018, Volume: 16, Issue:3

    Topics: Adjuvants, Immunologic; Administration, Intravesical; Animals; BCG Vaccine; Cell Proliferation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Imiquimod; Methylnitrosourea; Random Allocation; Rats; Rats, Inbred F344; Ribosomal Protein S6 Kinases, 70-kDa; Toll-Like Receptor 2; Toll-Like Receptor 4; Treatment Outcome; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2018
Ex vivo culture of tumor cells from N-methyl-N-nitrosourea-induced bladder cancer in rats: Development of organoids and an immortalized cell line.
    Urologic oncology, 2018, Volume: 36, Issue:4

    Topics: Animals; Carcinoma, Transitional Cell; Cell Differentiation; Cell Line, Tumor; Coculture Techniques; Female; Fibroblasts; Humans; Methylnitrosourea; Mice; Organoids; Primary Cell Culture; Rats; Rats, Inbred F344; Spheroids, Cellular; Urinary Bladder; Urinary Bladder Neoplasms

2018
The inhibitory effect of intravesical fisetin against bladder cancer by induction of p53 and down-regulation of NF-kappa B pathways in a rat bladder carcinogenesis model.
    Basic & clinical pharmacology & toxicology, 2014, Volume: 115, Issue:4

    Topics: Administration, Intravesical; Animals; Apoptosis; Apoptosis Regulatory Proteins; Carcinogenesis; Cell Proliferation; Down-Regulation; Female; Flavonoids; Flavonols; Methylnitrosourea; NF-kappa B; Rats; Rats, Wistar; Signal Transduction; Tumor Suppressor Protein p53; Up-Regulation; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2014
Urothelial carcinogen resistance driven by stronger Toll-like receptor 2 (TLR2) and Uroplakin III (UP III) defense mechanisms: a new model.
    World journal of urology, 2015, Volume: 33, Issue:3

    Topics: Animals; Apoptosis; Carcinoma, Transitional Cell; Cell Proliferation; Disease Models, Animal; Disease Resistance; Female; Methylnitrosourea; Phenotype; Proto-Oncogene Proteins c-myc; Rats; Rats, Inbred F344; Rats, Inbred Lew; Toll-Like Receptor 2; Urinary Bladder; Urinary Bladder Neoplasms; Uroplakin III

2015
Chemopreventive efficacy of naproxen and nitric oxide-naproxen in rodent models of colon, urinary bladder, and mammary cancers.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:11

    Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Butylhydroxybutylnitrosamine; Carcinogens; Colonic Neoplasms; Diet; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Naproxen; Nitric Oxide Donors; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Urinary Bladder Neoplasms

2009
Intervention of nicotine on MNU-induced bladder cancer in rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2011, Volume: 31, Issue:1

    Topics: Animals; Carcinogens; Carcinoma, Transitional Cell; Female; Methylnitrosourea; Mutation; Nicotine; Rats; Rats, Wistar; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms

2011
Functional characterization of the bladder cancer marker, BLCA-4.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-15, Volume: 10, Issue:4

    Topics: Amino Acid Sequence; Animals; Antigens; beta-Galactosidase; Biomarkers, Tumor; Carcinogens; Cell Nucleus; Clinical Trials as Topic; Cloning, Molecular; Disease Models, Animal; Disease Progression; DNA, Complementary; Female; Humans; Immunoblotting; Methylnitrosourea; Molecular Sequence Data; Nuclear Proteins; Protein Binding; Protein Structure, Tertiary; Rats; Rats, Inbred F344; RNA, Messenger; Sensitivity and Specificity; Sequence Homology, Amino Acid; Tissue Distribution; Transcription Factors; Transfection; Urinary Bladder Neoplasms

2004
Modification of N-Methyl-N-Nitrosourea initiated bladder carcinogenesis in Wistar rats by terephthalic acid.
    Toxicology and applied pharmacology, 2006, Jan-01, Volume: 210, Issue:1-2

    Topics: Animals; Carcinogenicity Tests; Cocarcinogenesis; Dose-Response Relationship, Drug; Hyperplasia; Male; Methylnitrosourea; Microscopy, Electron, Scanning; Phthalic Acids; Rats; Rats, Wistar; Sodium Bicarbonate; Urinalysis; Urinary Bladder; Urinary Bladder Calculi; Urinary Bladder Neoplasms

2006
Intravesical N-(4-hydroxyphenyl) retinamide and adriamycin induces apoptosis in bladder cancer.
    Frontiers in bioscience : a journal and virtual library, 2006, Sep-01, Volume: 11

    Topics: Administration, Intravesical; Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Cycle; Disease Models, Animal; Doxorubicin; Female; Fenretinide; Flow Cytometry; In Situ Nick-End Labeling; Methylnitrosourea; Rats; Rats, Wistar; Urinary Bladder Neoplasms

2006
Effects of ginger (Zingiber officinale Roscoe) on DNA damage and development of urothelial tumors in a mouse bladder carcinogenesis model.
    Environmental and molecular mutagenesis, 2006, Volume: 47, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Disease Models, Animal; DNA Damage; Male; Methylnitrosourea; Mice; Neoplasm Invasiveness; Plant Extracts; Urinary Bladder Neoplasms; Urologic Neoplasms; Zingiber officinale

2006
Cytochemical markers of bladder carcinogenesis.
    The Histochemical journal, 1981, Volume: 13, Issue:6

    Topics: 5'-Nucleotidase; 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Cell Membrane; Cell Transformation, Neoplastic; Female; Methylnitrosourea; Mice; Mice, Inbred C57BL; Microscopy, Electron; Neoplasms, Experimental; Nucleotidases; Organ Culture Techniques; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms

1981
Inactivation of antiadherence effect of bladder surface glycosaminoglycan by a complete urinary carcinogen (N-methyl-N-nitrosourea).
    The Journal of urology, 1983, Volume: 129, Issue:1

    Topics: Adhesiveness; Animals; Escherichia coli Infections; Glycosaminoglycans; Immunity, Innate; Membrane Proteins; Methylnitrosourea; Mucous Membrane; Nitrosourea Compounds; Rabbits; Urinary Bladder; Urinary Bladder Neoplasms

1983
Technical factors affecting the reproducibility of intravesical mouse bladder tumor implantation during therapy with Bacillus Calmette-Guérin.
    Cancer research, 1984, Volume: 44, Issue:7

    Topics: Animals; Female; Immunotherapy; Methylnitrosourea; Mice; Mice, Inbred Strains; Mycobacterium bovis; Neoplasm Transplantation; Urinary Bladder Neoplasms

1984
[Use of lymphocytic DNA by the urothelium of bladder tumors].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:7

    Topics: Animals; Cell Communication; DNA; Lymphocytes; Methylnitrosourea; Rats; Urinary Bladder Neoplasms

1984
Irreversibility of low-grade superficial rat bladder carcinomas.
    Cancer research, 1984, Volume: 44, Issue:10

    Topics: Animals; Carcinoma, Papillary; Male; Methylnitrosourea; Neoplasm Regression, Spontaneous; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urine

1984
Effects of 12-O-tetradecanoylphorbol-13-acetate on carcinogenesis in the heterotopically transplanted rat urinary bladder.
    Gan, 1984, Volume: 75, Issue:9

    Topics: Animals; Cell Division; Male; Methylnitrosourea; Phorbols; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Urinary Bladder; Urinary Bladder Neoplasms

1984
Promoting activities of butylated hydroxyanisole, butylated hydroxytoluene and sodium L-ascorbate on forestomach and urinary bladder carcinogenesis initiated with methylnitrosourea in F344 male rats.
    Gan, 1984, Volume: 75, Issue:9

    Topics: Animals; Anisoles; Ascorbic Acid; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Hyperplasia; Male; Methylnitrosourea; Papilloma; Rats; Rats, Inbred F344; Stomach; Stomach Neoplasms; Urinary Bladder Neoplasms

1984
Promotion of bladder tumours by endoscopic procedures in an animal model.
    British journal of urology, 1984, Volume: 56, Issue:6

    Topics: Animals; Catheterization; Cystoscopy; Diathermy; Female; Glycine; Inflammation; Methylnitrosourea; Organ Size; Rats; Rats, Inbred Strains; Sodium Chloride; Urinary Bladder Neoplasms; Water

1984
Multi-stage tumour development in the urinary bladder.
    Progress in clinical and biological research, 1983, Volume: 132B

    Topics: Adult; Age Factors; Animals; Cyclophosphamide; Humans; Methyl Methanesulfonate; Methylnitrosourea; Middle Aged; Ornithine Decarboxylase; Risk; Schistosomiasis; Urinary Bladder Calculi; Urinary Bladder Neoplasms

1983
Modification of chemical carcinogenesis by antioxidants.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Ethoxyquin; Kidney Neoplasms; Liver Neoplasms; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344; Stomach Neoplasms; Urinary Bladder Neoplasms

1983
Unusually high susceptibility of NZR/Gd rats to bladder cancer induction by low doses of nitrosomethylurea.
    Cancer letters, 1984, Volume: 22, Issue:2

    Topics: Animals; Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Disease Susceptibility; Female; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder Neoplasms; Urinary Catheterization

1984
The "promoting" activity of methyl methanesulphonate in rat bladder carcinogenesis.
    British journal of cancer, 1984, Volume: 50, Issue:1

    Topics: Animals; Carcinoma, Transitional Cell; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Methyl Methanesulfonate; Methylnitrosourea; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1984
Rapid induction of carcinoma in situ in dog urinary bladder by sequential treatment with N-methyl-N'-nitrosourea and N-butyl-N-(4-hydroxybutyl)-nitrosamine.
    Gan, 1984, Volume: 75, Issue:5

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma in Situ; Dogs; Drug Administration Schedule; Female; Methylnitrosourea; Nitrosamines; Nitrosourea Compounds; Time Factors; Urinary Bladder Neoplasms

1984
Capability of urinary components to enhance ornithine decarboxylase activity and promote urothelial tumorigenicity.
    Cancer research, 1983, Volume: 43, Issue:4

    Topics: Animals; Carboxy-Lyases; Carcinoma, Squamous Cell; Cell Line; Enzyme Induction; Female; Kinetics; Male; Methylnitrosourea; Neoplasms, Experimental; Ornithine Decarboxylase; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urine

1983
Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Adenocarcinoma, Papillary; Animals; Cocarcinogenesis; Liver Neoplasms; Male; Methylnitrosourea; Nitrosourea Compounds; Organ Specificity; Papilloma; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344; Saccharin; Thyroid Neoplasms; Urinary Bladder Neoplasms

1983
A minimal dose of N-methyl-N-nitrosourea carcinogenic to heterotopically transplanted rat urinary bladder.
    Carcinogenesis, 1983, Volume: 4, Issue:5

    Topics: Animals; Male; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urine

1983
Induction of bladder cancer in rats by fractionated intravesicular doses of N-methyl-N-nitrosourea.
    British journal of cancer, 1982, Volume: 45, Issue:3

    Topics: Animals; Carcinoma in Situ; Carcinoma, Transitional Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hyperplasia; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Precancerous Conditions; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Calculi; Urinary Bladder Neoplasms

1982
Rat bladder isograft model for focal carcinoma.
    The Journal of urology, 1982, Volume: 128, Issue:3

    Topics: Animals; Carcinoma, Transitional Cell; FANFT; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Thiazoles; Transplantation, Isogeneic; Urinary Bladder Neoplasms

1982
Syncarcinogenic action of saccharin or sodium cyclamate in the induction of bladder tumours in MNU-pretreated rats.
    Food and cosmetics toxicology, 1980, Volume: 18, Issue:6

    Topics: Animals; Body Weight; Carcinogens; Cyclamates; Drug Synergism; Eating; Female; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Saccharin; Urinary Bladder Neoplasms; Urologic Neoplasms

1980
The effect of single dose N-methyl-N-nitrosourea on bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide in rats.
    Investigative urology, 1981, Volume: 18, Issue:8

    Topics: Animals; Body Weight; Carcinoma, Papillary; Carcinoma, Transitional Cell; FANFT; Female; Hyperplasia; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Organ Size; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1981
Carcinogenesis in heterotopically-transplanted urinary bladder by N-methyl-N-nitrosourea: a model for initiation and promotion.
    Carcinogenesis, 1981, Volume: 2, Issue:6

    Topics: Animals; Carcinogens; Disease Models, Animal; Male; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Transplantation, Homologous; Urinary Bladder Neoplasms; Urine

1981
Increased agglutinability of bladder cells by concanavalin A after administration of carcinogens.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: 2-Acetylaminofluorene; 2-Naphthylamine; Benzidines; Carcinogens; Cell Aggregation; Concanavalin A; Cyclophosphamide; Drug Evaluation, Preclinical; Methylnitrosourea; Nitrosamines; Urinary Bladder; Urinary Bladder Neoplasms

1980
Ortho-toluene sulphonamide and saccharin in the promotion of bladder cancer in the rat.
    British journal of cancer, 1980, Volume: 42, Issue:1

    Topics: Animals; Body Weight; Drinking; Eating; Female; Kidney; Methylnitrosourea; Neoplasms, Experimental; Organ Size; Rats; Saccharin; Sulfonamides; Toluene; Tosyl Compounds; Urinary Bladder; Urinary Bladder Neoplasms

1980
Enhancement of transformation in vitro of a nontumorigenic rat urothelial cell line by interleukin 6.
    Cancer research, 1995, Oct-15, Volume: 55, Issue:20

    Topics: Animals; Antigens, CD; Carcinogens; Carcinoma; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Gene Expression Regulation, Neoplastic; In Vitro Techniques; Interleukin-1; Interleukin-6; Interleukin-8; Methylnitrosourea; Rats; Receptors, Interleukin; Receptors, Interleukin-6; RNA, Messenger; RNA, Neoplasm; Tumor Necrosis Factor-alpha; Urinary Bladder; Urinary Bladder Neoplasms

1995
Intraluminal epidermal growth factor affects growth of N-methyl-N-nitrosourea-initiated rat bladder carcinoma.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:5

    Topics: Animals; Carcinoma, Transitional Cell; Cell Division; Drug Synergism; Epidermal Growth Factor; Male; Methylnitrosourea; Neoplasm Transplantation; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1995
Intravesical suramin in the prevention of transitional cell carcinoma.
    Urology, 1995, Volume: 45, Issue:1

    Topics: Administration, Intravesical; Animals; Carcinoma, Transitional Cell; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Suramin; Urinary Bladder Neoplasms

1995
DNA methylation adduct formation and H-ras gene mutations in progression of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tumors caused by a single exposure to N-methyl-N-nitrosourea.
    Carcinogenesis, 1994, Volume: 15, Issue:12

    Topics: Administration, Oral; Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Deoxyguanosine; Disease Progression; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA, Neoplasm; Genes, ras; Injections, Intraperitoneal; Male; Methylation; Methylnitrosourea; Molecular Sequence Data; Neoplasm Invasiveness; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1994
Study of sodium saccharin co-carcinogenicity in the rat.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:3

    Topics: Animals; Carcinogenicity Tests; Carcinoma, Transitional Cell; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms

1994
Persistence of carcinogen-altered cell population in rat urothelium which can be promoted to tumors by chronic inflammatory stimulus.
    Cancer research, 1994, May-15, Volume: 54, Issue:10

    Topics: Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cystitis; Escherichia coli; Male; Methylnitrosourea; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1994
Enhancement of rat urinary bladder tumorigenesis by lipopolysaccharide-induced inflammation.
    Cancer research, 1993, Nov-01, Volume: 53, Issue:21

    Topics: Animals; Carcinogens; Hydrogen Peroxide; Inflammation; Lipopolysaccharides; Male; Methylnitrosourea; Neutrophils; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder Neoplasms

1993
Effect of epidermal growth factor and transforming growth factor beta 1 on growth and invasive potentials of newly established rat bladder carcinoma cell lines.
    International journal of cancer, 1993, Dec-02, Volume: 55, Issue:6

    Topics: Animals; Carcinoma, Transitional Cell; Cell Division; Collagenases; Epidermal Growth Factor; ErbB Receptors; Glycoproteins; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Methylnitrosourea; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Rats; RNA, Messenger; RNA, Neoplasm; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Urine

1993
Epidermal growth factor-responsive and -refractory carcinomas initiated with N-methyl-N-nitrosourea in rat urinary bladder.
    Cancer research, 1996, Jun-01, Volume: 56, Issue:11

    Topics: Animals; Carcinoma, Transitional Cell; Epidermal Growth Factor; ErbB Receptors; Gene Expression; In Situ Hybridization; Male; Membrane Glycoproteins; Methylnitrosourea; Neovascularization, Pathologic; Rats; Rats, Inbred F344; RNA, Messenger; Thrombospondins; Transforming Growth Factor alpha; Urinary Bladder Neoplasms

1996
Tumor-targeting potential of radioiodinated iododeoxyuridine in bladder cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:2

    Topics: Animals; Autoradiography; Carcinogens; Carcinoma, Transitional Cell; Female; Idoxuridine; Iodine Radioisotopes; Methylnitrosourea; Radionuclide Imaging; Rats; Rats, Inbred F344; Time Factors; Tissue Distribution; Urinary Bladder Neoplasms

1996
Transformation in vitro of a nontumorigenic rat urothelial cell line by hydrogen peroxide.
    Cancer research, 1996, Oct-15, Volume: 56, Issue:20

    Topics: Animals; Carcinoma, Transitional Cell; Cell Division; Cell Transformation, Neoplastic; Cystitis; Cytokines; Hydrogen Peroxide; Male; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Rats; Tumor Cells, Cultured; Tumor Stem Cell Assay; Urinary Bladder Neoplasms

1996
Lack of involvement of p53 gene mutations in N-methyl-N-nitrosourea-induced bladder tumor progression in N-butyl-N-(4-hydroxybutyl)nitrosamine-treated rats and no suppression by indomethacin.
    Cancer letters, 1997, May-19, Volume: 115, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cocarcinogenesis; Disease Progression; Genes, p53; Indomethacin; Male; Methylnitrosourea; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1997
p53 gene mutation in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder tumors and N-methyl-N-nitrosourea-induced colon tumors of rats.
    Cancer letters, 1997, Jul-15, Volume: 117, Issue:1

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Colonic Neoplasms; Exons; Genes, p53; Male; Methylnitrosourea; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1997
Lack of an antitumoral effect of immunomodulatory galactoside-specific mistletoe lectin on N-methyl-N-nitrosourea-induced urinary bladder carcinogenesis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1997, Volume: 49, Issue:3-4

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Papillary; Carcinoma, Squamous Cell; Female; Histiocytoma, Benign Fibrous; Methylnitrosourea; Mistletoe; Plant Preparations; Plant Proteins; Plants, Medicinal; Rats; Rats, Wistar; Ribosome Inactivating Proteins, Type 2; Toxins, Biological; Urinary Bladder Neoplasms

1997
Studies of initiation and promotion of carcinogenesis by N-nitroso compounds.
    Cancer letters, 1998, Jan-30, Volume: 123, Issue:2

    Topics: Animals; Carcinogens; Carcinoma, Transitional Cell; Diethylnitrosamine; Ethylnitrosourea; Male; Methylnitrosourea; Mutagens; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Rats; Rats, Inbred F344; Survival Rate; Urinary Bladder Neoplasms

1998
Inability of galactoside-specific mistletoe lectin to inhibit N-methyl-N-nitrosourea-induced tumor development in the urinary bladder of rats and to mediate a local cellular immune response after long-term administration.
    Journal of cancer research and clinical oncology, 1998, Volume: 124, Issue:2

    Topics: Adjuvants, Immunologic; Administration, Intravesical; Animals; Biomarkers, Tumor; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; Granulocytes; Immunohistochemistry; Killer Cells, Natural; Lectins; Macrophages; Methylnitrosourea; Mistletoe; Plant Lectins; Plant Preparations; Plant Proteins; Plants, Medicinal; Rats; Rats, Wistar; Ribosome Inactivating Proteins, Type 2; Toxins, Biological; Urinary Bladder; Urinary Bladder Neoplasms

1998
Exogenous epidermal growth factor exerts promoting action during the early phase of rat urinary bladder carcinogenesis.
    Japanese journal of cancer research : Gann, 1998, Volume: 89, Issue:10

    Topics: Animals; Carcinogens; Carcinoma, Transitional Cell; Epidermal Growth Factor; Male; Methylnitrosourea; Neoplasm Invasiveness; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder Neoplasms

1998
A comparative analysis of allelic imbalance events in chemically induced rat mammary, colon, and bladder tumors.
    Molecular carcinogenesis, 1999, Volume: 24, Issue:1

    Topics: Alleles; Animals; Azoxymethane; Butylhydroxybutylnitrosamine; Carcinogens; Chromosome Mapping; Codon; Colonic Neoplasms; Female; Genes, ras; Genetic Markers; Humans; Loss of Heterozygosity; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Microsatellite Repeats; Point Mutation; Rats; Rats, Inbred F344; Rats, Inbred WF; Urinary Bladder Neoplasms

1999
Transmurally absorbed intravesical chemotherapy with dimethylsulfoxide in an animal model.
    International journal of urology : official journal of the Japanese Urological Association, 1999, Volume: 6, Issue:2

    Topics: Administration, Intravesical; Animals; Antibiotics, Antineoplastic; Carcinogens; Dimethyl Sulfoxide; Disease Models, Animal; Epirubicin; Excipients; Hyperplasia; Male; Methylnitrosourea; Mucous Membrane; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms

1999
Antitumoral effect of recombinant mistletoe lectin on chemically induced urinary bladder carcinogenesis in a rat model.
    Cancer, 2001, Mar-01, Volume: 91, Issue:5

    Topics: Adjuvants, Immunologic; Administration, Intravesical; Alkylating Agents; Animals; Cell Transformation, Neoplastic; Female; Methylnitrosourea; Neoplasms, Experimental; Plant Preparations; Plant Proteins; Rats; Recombinant Proteins; Ribosome Inactivating Proteins, Type 2; Toxins, Biological; Urinary Bladder Neoplasms; Urothelium

2001
Possible involvement of O6-methylguanine formation and p53 dysfunction in mouse urinary bladder carcinogenesis.
    Mutation research, 2001, Jun-02, Volume: 477, Issue:1-2

    Topics: Animals; Butylhydroxybutylnitrosamine; Cacodylic Acid; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Mutational Analysis; Female; Guanine; Humans; Male; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Knockout; Mice, Transgenic; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Polymorphism, Single-Stranded Conformational; RNA, Messenger; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms

2001
Focal distribution of surface marker enzymes after long-term culture of adult rat bladder epithelium and methylnitrosourea (NNU)-induced bladder tumors.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1979, Volume: 27, Issue:9

    Topics: Alkaline Phosphatase; Animals; Cell Membrane; Epithelium; Female; Methylnitrosourea; Nucleotidases; Organ Culture Techniques; Rats; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1979
Effects of 13-cis and all-trans-retinoic acid on the development of bladder cancer in rats: an ultrastructural study.
    Scanning electron microscopy, 1979, Issue:3

    Topics: Animals; Cell Membrane; Female; Isomerism; Methylnitrosourea; Microscopy, Electron; Microscopy, Electron, Scanning; Nitrosourea Compounds; Rats; Structure-Activity Relationship; Tretinoin; Urinary Bladder Neoplasms

1979
Influence of dose of N-methyl-N-nitrosourea on the induction of urinary bladder cancer in rats.
    Cancer letters, 1979, Volume: 8, Issue:1

    Topics: Animals; Carcinoma, Transitional Cell; Dose-Response Relationship, Drug; Female; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Urethra; Urinary Bladder Neoplasms; Urinary Catheterization

1979
Induction of tumors in heterotopic bladder by topical application of N-methyl-N-nitrosourea and N-butyl-N-(3-carboxypropyl)nitrosamine.
    Cancer research, 1978, Volume: 38, Issue:9

    Topics: Animals; Carcinoma, Transitional Cell; Disease Models, Animal; Female; Hyperplasia; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Nitrosourea Compounds; Propionates; Rats; Rats, Inbred Strains; Transplantation, Isogeneic; Urinary Bladder; Urinary Bladder Neoplasms

1978
Prophylaxis of bladder tumor implantation. Intravesical and systemic chemotherapy.
    Urology, 1976, Volume: 7, Issue:1

    Topics: Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Disease Models, Animal; Doxorubicin; Female; Methylnitrosourea; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Thiotepa; Urinary Bladder; Urinary Bladder Neoplasms

1976
13-cis-retinoic acid: inhibition of bladder carcinogenesis in the rat.
    Science (New York, N.Y.), 1977, Feb-04, Volume: 195, Issue:4277

    Topics: Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Methylnitrosourea; Neoplasms, Experimental; Rats; Tretinoin; Urinary Bladder Neoplasms; Vitamin A

1977
Histopathological evaluation of the inhibition of rat bladder carcinogenesis by 13-cis-retinoic acid.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 2

    Topics: Animals; Epithelium; Female; Methylnitrosourea; Neoplasms, Experimental; Precancerous Conditions; Rats; Statistics as Topic; Tretinoin; Urinary Bladder Neoplasms; Vitamin A

1977
The importance of synergy between weak carcinogens in the induction of bladder cancer in experimental animals and humans.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 2

    Topics: 2-Naphthylamine; Animals; Carcinogens; Carcinogens, Environmental; Carcinoma, Transitional Cell; Cyclamates; Drug Synergism; Female; Humans; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Saccharin; Urinary Bladder Neoplasms

1977
[Papillomas of the urinary bladder induced by N-nitroso-N-methylurea in rats].
    Voprosy onkologii, 1976, Volume: 22, Issue:12

    Topics: Animals; Female; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Papilloma; Rats; Urinary Bladder; Urinary Bladder Neoplasms

1976
Susceptibility of urothelium to neoplastic cellular implantation.
    Urology, 1975, Volume: 5, Issue:6

    Topics: Animals; Carcinoma, Transitional Cell; Cystitis; Epithelium; FANFT; Female; Methylnitrosourea; Mice; Mice, Inbred C3H; Mucous Membrane; Neoplasm Transplantation; Neoplasms, Experimental; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1975
Organ culture of normal and carcinogen-treated rat bladder.
    Cancer research, 1976, Volume: 36, Issue:7 PT 2

    Topics: Animals; Culture Media; Female; Methylnitrosourea; Neoplasms, Experimental; Organ Culture Techniques; Precancerous Conditions; Rats; Urinary Bladder; Urinary Bladder Neoplasms

1976
Marked enhancement of rat urinary bladder carcinogenesis by heat-killed Escherichia coli.
    Cancer research, 1992, Oct-01, Volume: 52, Issue:19

    Topics: Administration, Intravesical; Animals; Body Weight; Buffers; Cell Wall; Escherichia coli; Hot Temperature; Hyperplasia; Male; Methylnitrosourea; Neoplasm Transplantation; Phosphates; Rats; Rats, Inbred F344; Sodium Chloride; Thymidine; Transplantation, Heterotopic; Tritium; Urinary Bladder; Urinary Bladder Neoplasms; Urine

1992
O6-alkylguanine-DNA-alkyltransferase activity and nitrosourea sensitivity in human cancer cell lines.
    British journal of cancer, 1992, Volume: 66, Issue:5

    Topics: Antineoplastic Agents; Cisplatin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Male; Methylnitrosourea; Methyltransferases; Nitrogen Mustard Compounds; O(6)-Methylguanine-DNA Methyltransferase; Testicular Neoplasms; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1992
Absence of ras oncogene activation in rat urinary bladder carcinomas induced by N-methyl-N-nitrosourea or N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Carcinogenesis, 1992, Volume: 13, Issue:12

    Topics: Animals; Base Sequence; Blotting, Western; Butylhydroxybutylnitrosamine; DNA, Single-Stranded; Gene Expression; Genes, ras; Male; Methylnitrosourea; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1992
[Inhibition of tumor induction by methylnitrosourea in resected urinary bladder].
    Arkhiv patologii, 1992, Volume: 54, Issue:11

    Topics: Animals; Cell Cycle; Female; Methylnitrosourea; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms

1992
Direct DNA sequencing of the rat neu oncogene transmembrane domain reveals no mutation in urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)nitrosamine, N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide or N-methyl-N-nitrosourea.
    Carcinogenesis, 1991, Volume: 12, Issue:10

    Topics: Amino Acid Sequence; Animals; Base Sequence; Butylhydroxybutylnitrosamine; DNA, Neoplasm; FANFT; Male; Membranes; Methylnitrosourea; Molecular Sequence Data; Mutation; Oncogenes; Polymerase Chain Reaction; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; Receptor, ErbB-2; Saccharin; Uracil; Urinary Bladder Neoplasms

1991
Correlation of cytokeratin patterns with histopathology during neoplastic progression in the rat urinary bladder.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 1990, Volume: 58, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Epithelium; Female; Hyperplasia; Immunoenzyme Techniques; Immunohistochemistry; Keratins; Methylnitrosourea; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1990
ras gene alterations in invasive and non-invasive rat bladder carcinomas induced by N-methyl-N-nitrosourea.
    British journal of cancer, 1991, Volume: 64, Issue:1

    Topics: Animals; Blotting, Southern; Carcinoma; Cell Line; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Methylnitrosourea; Mice; Mice, Nude; Neoplasm Invasiveness; Nucleic Acid Hybridization; Oncogene Protein p21(ras); Rats; Rats, Inbred F344; Transfection; Urinary Bladder Neoplasms

1991
Specific chromosome change associated with acquisition in vivo of tumorigenicity in carcinogen-induced rat urinary bladder carcinoma cells.
    Genes, chromosomes & cancer, 1991, Volume: 3, Issue:3

    Topics: Animals; Cell Line; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Diploidy; Genetic Markers; Karyotyping; Male; Methylnitrosourea; Neoplasm Transplantation; Probability; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1991
Different modifying responses of capsaicin in a wide-spectrum initiation model of F344 rat.
    Journal of Korean medical science, 1991, Volume: 6, Issue:1

    Topics: Animals; Capsaicin; Cocarcinogenesis; Diethylnitrosamine; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1991
Organ-specific modification of tumor development by low-dose combinations of agents in a rat wide-spectrum carcinogenesis model.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:7

    Topics: Animals; Carcinogens; Diethylnitrosamine; Disease Models, Animal; Dose-Response Relationship, Drug; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Organ Specificity; Pepsinogens; Pylorus; Rats; Rats, Inbred F344; Stomach Neoplasms; Urinary Bladder Neoplasms

1991
Induction of invasive carcinomas of the seminal vesicles and coagulating glands of F344 rats by administration of N-methylnitrosourea or N-nitrosobis(2-oxopropyl)amine and followed by testosterone propionate with or without high-fat diet.
    Carcinogenesis, 1991, Volume: 12, Issue:11

    Topics: Animals; Body Weight; Bulbourethral Glands; Colonic Neoplasms; Dietary Fats; Drug Synergism; Genital Neoplasms, Male; Kidney Neoplasms; Lung Neoplasms; Male; Methylnitrosourea; Nitrosamines; Organ Size; Prostate; Prostatic Neoplasms; Radioimmunoassay; Rats; Rats, Inbred F344; Seminal Vesicles; Testosterone; Urethral Neoplasms; Urinary Bladder Neoplasms

1991
Experimental intravesical therapy for superficial transitional cell carcinoma in a rat bladder tumor model.
    The Journal of urology, 1991, Volume: 145, Issue:3

    Topics: Administration, Intravesical; Animals; BCG Vaccine; Carcinoma, Transitional Cell; Doxorubicin; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Recombinant Proteins; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms

1991
Inhibition of tumour development in the partially resected, proliferating rat urinary bladder.
    Acta histochemica. Supplementband, 1990, Volume: 39

    Topics: Animals; Autoradiography; Cell Division; Cystectomy; DNA Replication; Female; Methylnitrosourea; Rats; Rats, Inbred Strains; Thymidine; Tritium; Urinary Bladder; Urinary Bladder Neoplasms

1990
Histopathology of N-methyl-N-nitrosourea-induced mesenchymal tumours of the rat urinary bladder.
    Journal of experimental pathology (Oxford, England), 1990, Volume: 71, Issue:3

    Topics: Animals; Female; Fibroma; Hemangioma; Histiocytoma, Benign Fibrous; Methylnitrosourea; Mitotic Index; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms

1990
Characterization of an N-methyl-N-nitrosourea-induced autochthonous rat bladder cancer model.
    Cancer research, 1990, Oct-15, Volume: 50, Issue:20

    Topics: Animals; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; Chromosome Aberrations; Disease Models, Animal; FANFT; Female; Methylnitrosourea; Proto-Oncogene Proteins p21(ras); Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1990
In vitro malignant conversion of low-grade rat urinary bladder carcinoma cells by exposure to N-methyl-N-nitrosourea.
    Cancer research, 1990, Nov-01, Volume: 50, Issue:21

    Topics: Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Clone Cells; Codon; Dose-Response Relationship, Drug; Genes, ras; Methylnitrosourea; Mice; Mutation; Neoplasm Invasiveness; Neoplasm Transplantation; Oncogene Protein p21(ras); Plasminogen Activators; Rats; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1990
Rat urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine and N-methyl-N-nitrosourea.
    Urological research, 1990, Volume: 18, Issue:5

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1990
Gamma glutamyl transpeptidase activity in rat urothelium treated with bladder carcinogens.
    Cancer letters, 1985, Volume: 29, Issue:1

    Topics: Animals; Animals, Newborn; Butylhydroxybutylnitrosamine; Carcinogens; Female; gamma-Glutamyltransferase; Histocytochemistry; Hyperplasia; Male; Methylnitrosourea; Mucous Membrane; Rats; Staining and Labeling; Time Factors; Urinary Bladder Neoplasms

1985
Induction of morphological changes in the urothelium of cultured adult rat bladder by sodium saccharin and sodium cyclamate.
    Carcinogenesis, 1986, Volume: 7, Issue:5

    Topics: Animals; Cyclamates; Epithelium; Female; Hyperplasia; Methylnitrosourea; Microscopy, Electron, Scanning; Organ Culture Techniques; Rats; Rats, Inbred F344; Saccharin; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1986
Effects of treatment with N-methyl-N-nitrosourea, artificial sweeteners, and cyclophosphamide on adult rat urinary bladder in vitro.
    Laboratory investigation; a journal of technical methods and pathology, 1987, Volume: 57, Issue:4

    Topics: Animals; Cyclamates; Cyclophosphamide; Epithelium; Female; Hyperplasia; Methylnitrosourea; Microscopy, Electron; Microscopy, Electron, Scanning; Organ Culture Techniques; Precancerous Conditions; Rats; Rats, Inbred Strains; Saccharin; Sweetening Agents; Urinary Bladder; Urinary Bladder Neoplasms

1987
Modifying effects of simultaneous treatment with butylated hydroxyanisole (BHA) on rat tumor induction by 3,2'-dimethyl-4-aminobiphenyl, 2,2'-dihydroxy-di-n-propylnitrosamine and N-methylnitrosourea.
    Carcinogenesis, 1989, Volume: 10, Issue:12

    Topics: Aminobiphenyl Compounds; Animals; Body Weight; Butylated Hydroxyanisole; Carcinogens; Hyperplasia; Kidney; Liver; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosamines; Organ Size; Precancerous Conditions; Rats; Rats, Inbred F344; Stomach Neoplasms; Tongue Neoplasms; Urinary Bladder Neoplasms

1989
Cell cycle dependence of N-methyl-N-nitrosourea-induced tumour development in the proliferating, partially resected rat urinary bladder.
    British journal of experimental pathology, 1989, Volume: 70, Issue:2

    Topics: Animals; Cell Cycle; Cell Division; Female; Kidney; Methylnitrosourea; Mitosis; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms

1989
Strong promoting activity by uracil on urinary bladder carcinogenesis and a possible inhibitory effect on thyroid tumorigenesis in rats initiated with N-methyl-N-nitrosourea.
    Carcinogenesis, 1989, Volume: 10, Issue:8

    Topics: Adenocarcinoma; Animals; Body Weight; Carcinogens; Carcinoma, Transitional Cell; Male; Methylnitrosourea; Organ Size; Papilloma; Rats; Rats, Inbred F344; Reference Values; Thyroid Neoplasms; Uracil; Urinary Bladder Neoplasms

1989
Immunohistochemistry and cytochemistry of experimental rat bladder cancer: binding of the lectins PNA and WGA and of a Le(Y) mouse monoclonal antibody.
    The Journal of urology, 1989, Volume: 141, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antigens, Tumor-Associated, Carbohydrate; Arachis; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; Female; Immunohistochemistry; Lectins; Lewis Blood Group Antigens; Methylnitrosourea; Peanut Agglutinin; Plant Lectins; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms; Wheat Germ Agglutinins

1989
Effects of alpha-difluoromethylornithine on initiation and promotion of urinary bladder carcinogenesis in a heterotopically transplanted rat urinary bladder.
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:3

    Topics: Animals; Eflornithine; Male; Methylnitrosourea; Neoplasm Transplantation; Ornithine Decarboxylase Inhibitors; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1988
Conversion from low grade to high grade of rat urinary bladder carcinomas.
    Cancer research, 1988, Mar-01, Volume: 48, Issue:5

    Topics: Animals; Carcinoma; Male; Methylnitrosourea; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1988
Production of urothelial tumors in the heterotopic bladder of rats by instillation of N-glucuronosyl or N-acetyl derivatives of N-hydroxy-2-aminofluorene.
    Cancer research, 1987, Jul-01, Volume: 47, Issue:13

    Topics: 2-Acetylaminofluorene; Animals; Epithelium; Fluorenes; Glucuronates; Hydroxyacetylaminofluorene; Male; Metabolic Clearance Rate; Methylnitrosourea; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1987
Growth promotion by silk sutures in the urinary bladder of rat.
    Experimental and molecular pathology, 1987, Volume: 47, Issue:2

    Topics: Animals; Cocarcinogenesis; Female; Insect Proteins; Male; Methylnitrosourea; Mucous Membrane; Proteins; Rats; Rats, Brattleboro; Silk; Sutures; Urinary Bladder Calculi; Urinary Bladder Neoplasms

1987
Modification of N-methyl-N-nitrosourea-induced urinary bladder carcinogenesis in rats following stimulation of urothelial proliferation by a partial cystectomy.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:1

    Topics: Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Epithelial Cells; Epithelium; Female; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1986
Effects of formalin-induced injuries on urinary bladder carcinogenesis.
    Cancer letters, 1986, Volume: 32, Issue:2

    Topics: Animals; Cocarcinogenesis; Fibrosis; Formaldehyde; Hyperplasia; Male; Methylnitrosourea; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1986
Quantitative assessments of the cytotoxicity of bladder carcinogens towards cultured normal human uroepithelial cells.
    Carcinogenesis, 1986, Volume: 7, Issue:10

    Topics: Aminobiphenyl Compounds; Animals; Biotransformation; Carcinogens; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Epithelium; Fibroblasts; Humans; Methylnitrosourea; Proto-Oncogenes; Rats; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1986
Induction of high-grade, high-stage carcinomas in the rat urinary bladder.
    Cancer, 1987, Feb-01, Volume: 59, Issue:3

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelium; Flow Cytometry; Hyperplasia; Methylnitrosourea; Neoplasm Transplantation; Nitrosamines; Rats; Urinary Bladder; Urinary Bladder Neoplasms

1987
Prevention of inhibitory effects of alpha-difluoromethylornithine on rat urinary bladder carcinogenesis by exogenous putrescine.
    Cancer biochemistry biophysics, 1986, Volume: 8, Issue:4

    Topics: Animals; Cell Division; Epithelial Cells; Male; Methylnitrosourea; Polyamines; Putrescine; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1986
The effects of saccharin on the development of neoplastic lesions initiated with N-methyl-N-nitrosourea in the rat urothelium.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 7, Issue:4

    Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Epithelium; Female; Methylnitrosourea; Rats; Rats, Inbred Strains; Risk; Saccharin; Urinary Bladder Neoplasms

1986
Standardized tumor rates for chronic bioassays.
    Biometrics, 1986, Volume: 42, Issue:4

    Topics: Animals; Carcinogens; Drug Evaluation, Preclinical; Female; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Risk; Urinary Bladder Neoplasms

1986
Effect of 514.5-nm argon ion laser radiation on hematoporphyrin derivative-treated bladder tumor cells in vitro and in vivo.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:3

    Topics: Animals; Female; Hematoporphyrins; Humans; In Vitro Techniques; Laser Therapy; Methylnitrosourea; Mice; Mice, Inbred C3H; Photochemotherapy; Rats; Rats, Inbred Strains; Spectrophotometry; Urinary Bladder Neoplasms

1985
Inhibition of carcinogenesis by alpha-difluoromethylornithine in heterotopically transplanted rat urinary bladders.
    Cancer research, 1985, Volume: 45, Issue:2

    Topics: Animals; Eflornithine; Male; Methylnitrosourea; Ornithine; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine; Urinary Bladder; Urinary Bladder Neoplasms

1985
N-methyl-N-nitrosourea induces dysplasia and cell surface markers of neoplasia in long-term rat bladder organ cultures.
    Carcinogenesis, 1985, Volume: 6, Issue:7

    Topics: Animals; Cell Differentiation; Cell Membrane; Cell Transformation, Neoplastic; Epithelial Cells; Epithelium; Female; Methylnitrosourea; Microscopy, Electron, Scanning; Microvilli; Nitrosourea Compounds; Organ Culture Techniques; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1985