Page last updated: 2024-08-21

methylnitrosourea and Benign Neoplasms

methylnitrosourea has been researched along with Benign Neoplasms in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	21 (55.26)	18.7374
1990's	4 (10.53)	18.2507
2000's	7 (18.42)	29.6817
2010's	5 (13.16)	24.3611
2020's	1 (2.63)	2.80

Authors

Authors	Studies
Aksoy, Y; Anlar, HG; Aydemir, D; Bacanlı, M; Ozcan, M; Ulusu, NN	1
Engelward, BP; Gong, G; Kiraly, O; Roytman, MD; Samson, LD; Yamada, Y	1
Lindgren, BR; Sinha, AA; Wilson, MJ	1
Bailey, KL; Ball, DJ; Lorenzen, MJ; Morton, D; Stout, CL; Weaver, RJ; White, KA	1
Demová, H; Houška, M; Polívková, Z; Šmerák, P	1
Barbisan, LF; Bidinotto, LT; Costa, CA; Costa, M; Rodrigues, MA	1
Murasaki, T; Nakanishi, M; Ogawa, K; Shirai, T; Sugiura, S	1
Bao, BY; Hsu, JW; Lee, YF; Li, WX; Lin, TH; Messing, E; Messing, J; Sheu, TJ; Ting, HJ; Yan, SJ; Yasmin-Karim, S; Zeng, W	1
Murugesan, S; Noronha, OP; Samuel, AM; Shetty, SJ; Srivastava, TS	1
Blend, MJ; Dagar, S; Krishnadas, A; Onyüksel, H; Rubinstein, I	1
DRUCKREY, H; IVANKOVIC, S; PREUSSMANN, R; STEINHOFF, D	1
DRUCKREY, H; IVANKOVIC, S; PREUSSMANN, R	1
Ahn, D; Diaz, R; Garcia-Espana, A; Lopez-Barcons, L; Mangues, R; Matthews, J; Pellicer, A; Perez-Soler, R; Yoon, A	1
Chang, WC; Chuang, JY; Hung, JJ; Liu, YW; Wang, YT; Yeh, SH	1
Bychkov, MB; Perevodchikova, NI	1
Anisimov, VN	2
Vernie, LN	1
Chau, KK; Edwards, MB	1
Edwards, MB	1
Jänisch, W; Schmidt, T	1
Thompson, HJ	1
Dosch, J; Fritz, G; Kaina, B; Thielmann, HW	1
Heddle, JA	1
Selby, PB	1
Dement'eva, NP; Korman, DB	1
Levey, GS; Vesely, DL	1
Cayama, E; Farber, E; Sarma, DS; Tsuda, H	1
Lokich, JJ; Skarin, AT	1
Dement'eva, ND; Korman, DB	1
Anders, A; Barnekow, A; Schartl, M; Schmidt, CR	1
Barbacid, M	1
Dement'eva, NP	1
Topal, MD	1
Gor'kov, VA; Kim, OA; Korman, DB	1
Chun, HG; Cradock, J; Davignon, P; Grieshaber, C; Hoth, D; Leyland-Jones, B; Moon, R; Rifkind, R; Shoemaker, D; Wolpert-DeFilippes, M	1
Fukushima, S; Ito, N; Tsuda, H	1
Harris, CC	1

Reviews

10 review(s) available for methylnitrosourea and Benign Neoplasms

Article	Year
Role of age in host sensitivity to carcinogens. IARC scientific publications, 1983, Issue:51 Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Carcinogens; Colonic Neoplasms; DNA Repair; Female; Humans; Male; Methylnitrosourea; Neoplasms; Uterine Neoplasms; Vaginal Neoplasms	1983
Selenium in carcinogenesis. Biochimica et biophysica acta, 1984, Volume: 738, Issue:4 Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Cisplatin; Environmental Exposure; Epidemiologic Methods; Glutathione Peroxidase; Humans; Leukemia; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Neoplasms; Public Opinion; Selenium; United States	1984
Effect of exercise intensity and duration on the induction of mammary carcinogenesis. Cancer research, 1994, Apr-01, Volume: 54, Issue:7 Suppl Topics: Animals; Breast Neoplasms; Exercise; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms; Physical Conditioning, Animal; Rats; Risk Factors	1994
The use of transgenic animals in research. Environmental and molecular mutagenesis, 1998, Volume: 32, Issue:2 Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Animals, Genetically Modified; Carcinogens, Environmental; Cell Transformation, Neoplastic; Codon; Genes, ras; Liver; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Knockout; Mitosis; Mutagenesis; Mutagenicity Tests; Mutagens; Neoplasms; Polymerase Chain Reaction; Rats; Sensitivity and Specificity; Transgenes	1998
Oncogenes and human cancer: cause or consequence? Carcinogenesis, 1986, Volume: 7, Issue:7 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Chromosome Mapping; Gene Expression Regulation; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms; Neoplasms, Experimental; Oncogenes; Proto-Oncogenes; Rats; Retroviridae; Skin Neoplasms	1986
[Nitrosomethylurea in the clinical chemotherapy of malignant tumors]. Voprosy onkologii, 1988, Volume: 34, Issue:1 Topics: Humans; Methylnitrosourea; Neoplasms	1988
DNA repair, oncogenes and carcinogenesis. Carcinogenesis, 1988, Volume: 9, Issue:5 Topics: Alkylation; Animals; Codon; DNA Repair; Humans; Methylnitrosourea; Mutation; Neoplasms; Oncogenes	1988
Hexamethylene bisacetamide: a polar-planar compound entering clinical trials as a differentiating agent. Cancer treatment reports, 1986, Volume: 70, Issue:8 Topics: Acetamides; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cell Line; Cyclophosphamide; Dogs; Drug Evaluation, Preclinical; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms; Rats; Tumor Stem Cell Assay	1986
Carcinogenicity and modification of the carcinogenic response by BHA, BHT, and other antioxidants. Critical reviews in toxicology, 1985, Volume: 15, Issue:2 Topics: Animals; Anisoles; Antioxidants; Ascorbic Acid; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cocarcinogenesis; Drug Synergism; Humans; Kidney Neoplasms; Liver Neoplasms; Methylnitrosourea; Neoplasms; Species Specificity; Stomach Neoplasms; Urinary Bladder Neoplasms	1985
Cause and prevention of lung cancer. Seminars in oncology, 1974, Volume: 1, Issue:3 Topics: Animals; Asbestos; Benzopyrenes; Cricetinae; Disease Models, Animal; Humans; Lung Neoplasms; Methylnitrosourea; Neoplasms; Neoplasms, Experimental; Orthomyxoviridae; Smoking; Vitamin A	1974

Trials

1 trial(s) available for methylnitrosourea and Benign Neoplasms

Article	Year
Nitrosourea combination chemotherapy: 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (methyl-CCNU) and cyclophosphamide. Oncology, 1975, Volume: 32, Issue:3-4 Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methylnitrosourea; Middle Aged; Neoplasms; Nitrosourea Compounds; Stomach Neoplasms	1975

Article

Year

Nitrosourea combination chemotherapy: 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (methyl-CCNU) and cyclophosphamide.

Oncology, 1975, Volume: 32, Issue:3-4

Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methylnitrosourea; Middle Aged; Neoplasms; Nitrosourea Compounds; Stomach Neoplasms

1975

Other Studies

27 other study(ies) available for methylnitrosourea and Benign Neoplasms

Article	Year
Protective Effects of Antioxidant Chlorophyllin in Chemically Induced Breast Cancer Model In vivo. Biological trace element research, 2021, Volume: 199, Issue:12 Topics: Animals; Antioxidants; Chlorophyllides; Female; Methylnitrosourea; Neoplasms; Rats; Rats, Sprague-Dawley	2021
DNA glycosylase activity and cell proliferation are key factors in modulating homologous recombination in vivo. Carcinogenesis, 2014, Volume: 35, Issue:11 Topics: Animals; Carcinogenesis; Cell Proliferation; DNA Damage; DNA Glycosylases; DNA Methylation; DNA Repair; Homologous Recombination; Humans; Methylnitrosourea; Mice; N-Glycosyl Hydrolases; Neoplasms	2014
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats. Experimental and molecular pathology, 2008, Volume: 85, Issue:2 Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Cyclohexenes; Dietary Supplements; Disease Models, Animal; Genitalia, Male; Incidence; Inositol; Limonene; Male; Matrix Metalloproteinases; Methylnitrosourea; Neoplasms; Plasminogen Activators; Random Allocation; Rats; Rats, Wistar; Terpenes; Time Factors	2008
N-Methyl-N-Nitrosourea (MNU): A positive control chemical for p53+/- mouse carcinogenicity studies. Toxicologic pathology, 2008, Volume: 36, Issue:7 Topics: Adenocarcinoma; Adenoma; Animals; Carcinogenicity Tests; Carcinogens; CD3 Complex; Duodenal Neoplasms; Female; Genes, p53; Heterozygote; Injections, Intraperitoneal; Intestine, Small; Jejunal Neoplasms; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Knockout; Neoplasms; Thymus Gland; Thymus Neoplasms	2008
Antimutagenic effects of lycopene and tomato purée. Journal of medicinal food, 2010, Volume: 13, Issue:6 Topics: Aflatoxin B1; Animals; Antimutagenic Agents; Bone Marrow Cells; Carcinogens; Carotenoids; Dose-Response Relationship, Drug; Fruit; Liver; Lycopene; Male; Methylnitrosourea; Mice; Mice, Inbred BALB C; Micronucleus Tests; Mutagenicity Tests; Mutagens; Neoplasms; Quinolines; Rats; Rats, Wistar; Salmonella typhimurium; Solanum lycopersicum	2010
Modifying effects of lemongrass essential oil on specific tissue response to the carcinogen N-methyl-N-nitrosurea in female BALB/c mice. Journal of medicinal food, 2012, Volume: 15, Issue:2 Topics: Animals; Apoptosis; Carcinogens; Cell Cycle; Cymbopogon; Female; Humans; Methylnitrosourea; Mice; Neoplasms; Organ Specificity; Plant Oils; Terpenes	2012
Organ differences in the impact of p27(kip1) deficiency on carcinogenesis induced by N-methyl-N-nitrosourea. Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:6 Topics: Adenocarcinoma; Alkylating Agents; Animals; Antimetabolites; Body Weight; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p27; Genotype; Immunohistochemistry; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Knockout; Neoplasms; Organ Size; Organ Specificity	2013
A positive feedback signaling loop between ATM and the vitamin D receptor is critical for cancer chemoprevention by vitamin D. Cancer research, 2012, Feb-15, Volume: 72, Issue:4 Topics: Acid Anhydride Hydrolases; Animals; Ataxia Telangiectasia Mutated Proteins; ATP-Binding Cassette Transporters; Cell Cycle Proteins; DNA Damage; DNA Repair; DNA-Binding Proteins; Male; Methylnitrosourea; Mice; Mice, Nude; Mutation; Neoplasms; Oxidative Stress; Phosphorylation; Protein Serine-Threonine Kinases; Receptor Cross-Talk; Receptors, Calcitriol; Signal Transduction; Tumor Suppressor Proteins; Vitamin D	2012
Preparation and biological evaluation of the new chlorin photosensitizer T3,4BCPC for detection and treatment of tumors. Journal of photochemistry and photobiology. B, Biology, 2002, Volume: 68, Issue:1 Topics: Animals; Anthracenes; Female; Glioma; Isotope Labeling; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms; Photosensitizing Agents; Porphyrins; Radiopharmaceuticals; Rats; Rats, Wistar; Technetium; Time Factors; Tissue Distribution	2002
VIP grafted sterically stabilized liposomes for targeted imaging of breast cancer: in vivo studies. Journal of controlled release : official journal of the Controlled Release Society, 2003, Aug-28, Volume: 91, Issue:1-2 Topics: Animals; Carcinogens; Drug Carriers; Drug Compounding; Female; Image Processing, Computer-Assisted; Liposomes; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms; Particle Size; Radionuclide Imaging; Radiopharmaceuticals; Rats; Technetium Tc 99m Exametazime; Tissue Distribution; Vasoactive Intestinal Peptide	2003
[INDUCTION OF CANCER BY A SINGLE DOSE OF METHYLNITROSO-UREA AND VARIOUS DIALKYLNITROSAMINES IN RATS]. Zeitschrift fur Krebsforschung, 1964, Feb-07, Volume: 66 Topics: Brain Neoplasms; Carcinogens; Esophageal Neoplasms; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Methylnitrosourea; Neoplasms; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Ovarian Neoplasms; Paranasal Sinus Neoplasms; Rats; Research; Sarcoma; Sarcoma, Experimental; Toxicology	1964
[SELECTIVE INDUCTION OF MALIGNANT TUMORS IN THE BRAIN AND SPINAL CORD OF RATS BY N-METHYL-N-NITROSOUREA]. Zeitschrift fur Krebsforschung, 1965, Feb-03, Volume: 66 Topics: Brain; Brain Neoplasms; DNA; DNA, Neoplasm; Methylnitrosourea; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Nitroso Compounds; Organ Specificity; Research; RNA; RNA, Neoplasm; Spinal Cord Neoplasms; Toxicology	1965
Complex effects of Ras proto-oncogenes in tumorigenesis. Carcinogenesis, 2004, Volume: 25, Issue:4 Topics: Animals; Carcinogens; Cell Line, Tumor; Fibrosarcoma; Genes, ras; Lymphoma, B-Cell; Male; Mammary Tumor Virus, Mouse; Methylnitrosourea; Mice; Mice, Knockout; Neoplasms; Proto-Oncogene Mas	2004
Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis. Molecular biology of the cell, 2008, Volume: 19, Issue:3 Topics: Animals; Arachidonate 12-Lipoxygenase; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Female; Humans; Methylnitrosourea; Mitogen-Activated Protein Kinase 8; Mitosis; Mutant Proteins; Neoplasms; Phosphorylation; Phosphothreonine; Protein Transport; Rats; Rats, Sprague-Dawley; Sp1 Transcription Factor; Thermodynamics; Transcription, Genetic	2008
Modern problems of clinical chemotherapy of malignant tumours. Archiv fur Geschwulstforschung, 1980, Volume: 50, Issue:7 Topics: Antineoplastic Agents; Carcinoma, Small Cell; Carubicin; Dacarbazine; Dactinomycin; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Melanoma; Methylnitrosourea; Neoplasms; Sarcoma; Skin Neoplasms; Soft Tissue Neoplasms; Vincristine	1980
Topical carcinogenesis by N-methyl-N-nitrosourea in Syrian hamster cheek-pouch and oral mucosa. Archives of oral biology, 1984, Volume: 29, Issue:3 Topics: Absorption; Animals; Cheek; Cricetinae; Female; Male; Mesocricetus; Methylnitrosourea; Mouth Mucosa; Mouth Neoplasms; Neoplasms; Nitrosourea Compounds; Papilloma	1984
Effects of n-methylnitrosourea on oral and dental tissues in the inbred Lewis rat. Archives of oral biology, 1980, Volume: 25, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Female; Incisor; Male; Methylnitrosourea; Mouth Mucosa; Neoplasms; Nitrosourea Compounds; Rats; Rats, Inbred Lew	1980
Carcinogenesis and aging. I. Modifying effects of aging on N-methyl-N-nitrosourea-induced carcinogenesis in female rats. Experimental pathology, 1981, Volume: 19, Issue:2 Topics: Aging; Animals; Female; Kidney Neoplasms; Leukemia; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms; Nitrosourea Compounds; Rats; Thymoma; Uterine Cervical Neoplasms; Vaginal Neoplasms	1981
[Tumour induction by methylnitrosourea in clawed frogs (Xenopus laevis) (author's transl)]. Archiv fur Geschwulstforschung, 1980, Volume: 50, Issue:4 Topics: Adenocarcinoma; Animals; Kidney Diseases, Cystic; Kidney Neoplasms; Kidney Pelvis; Methylnitrosourea; Neoplasms; Nitrosourea Compounds; Papilloma; Sarcoma; Xenopus laevis	1980
Molecular and cellular characterization of Mex-/methylation-resistant phenotype. Gene and cDNA cloning, serum dependence, and tumor suppression of transfectant strains. The Journal of biological chemistry, 1993, Oct-05, Volume: 268, Issue:28 Topics: Amino Acid Sequence; Animals; Blood; CHO Cells; Cloning, Molecular; Cricetinae; DNA; DNA Repair; Drug Resistance; HeLa Cells; Humans; Methylation; Methylnitronitrosoguanidine; Methylnitrosourea; Molecular Sequence Data; Mutagens; Neoplasms; Nucleic Acid Hybridization; Phenotype; Sequence Homology, Amino Acid; Transfection	1993
Reasons it is doubtful that preconceptional paternal irradiation with plutonium-239 had any effect on cancer induction by methyl-nitroso-urea. British journal of cancer, 1999, Volume: 81, Issue:6 Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA Damage; Male; Methylnitrosourea; Mice; Neoplasms; Paternal Exposure; Plutonium; Reproducibility of Results	1999
[Nitrosomethylurea -- 30 years of study and use in the treatment of cancer patients]. Voprosy onkologii, 2001, Volume: 47, Issue:6 Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Female; History, 20th Century; Humans; Male; Methylnitrosourea; Neoplasms; Randomized Controlled Trials as Topic; Russia; Time Factors; USSR	2001
Enhancement of human guanylate cyclase activity by chemical carcinogens. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 155, Issue:3 Topics: Enzyme Activation; Guanylate Cyclase; Humans; Hydrazines; Methylnitrosourea; Neoplasms; Nitrosourea Compounds; Solubility; Streptozocin	1977
Initiation of chemical carcinogenesis requires cell proliferation. Nature, 1978, Sep-07, Volume: 275, Issue:5675 Topics: Animals; Carcinogens; Cell Division; Hepatectomy; Liver; Male; Methylnitrosourea; Neoplasms; Phenotype; Rats; Time Factors	1978
[Nitrosomethylurea in polychemotherapy of malignant tumors]. Sovetskaia meditsina, 1977, Issue:8 Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell; Drug Therapy, Combination; Humans; Lung Neoplasms; Methylnitrosourea; Neoplasms; Nitrosourea Compounds	1977
Elevated expression of the cellular src gene in tumors of differing etiologies in Xiphophorus. International journal of cancer, 1985, Aug-15, Volume: 36, Issue:2 Topics: Animals; Ethylnitrosourea; Fish Diseases; Fishes; Genotype; Hybridization, Genetic; Methylnitrosourea; Neoplasms; Neoplasms, Radiation-Induced; Oncogenes; Phosphoproteins; Protein Kinases; Proto-Oncogene Proteins pp60(c-src); Testosterone	1985
[Pharmacokinetics of nitrosomethylurea in oncologic patients]. Voprosy onkologii, 1988, Volume: 34, Issue:6 Topics: Adult; Aged; Female; Humans; Lung Neoplasms; Lymphoma; Male; Melanoma; Methylnitrosourea; Middle Aged; Neoplasms	1988