methylnitrosourea has been researched along with Abnormalities, Drug-Induced in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (54.84) | 18.7374 |
| 1990's | 10 (32.26) | 18.2507 |
| 2000's | 4 (12.90) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holladay, SD; Prater, MR; Ward, DL; Zimmerman, KL | 1 |
| Holladay, SD; Laudermilch, CL; Prater, MR; Saunders, GK; Sponenberg, DP; Ward, DL | 1 |
| Holladay, SD; Laudermilch, CL; Renee Prater, M; Zimmerman, KL | 1 |
| Takeuchi, IK | 1 |
| Chang, HW; Lin, JK; Lin-Shiau, SY; Yen, JY | 1 |
| Iannaccone, PM | 1 |
| Matsumoto, S; Sato, H; Sato, N; Tamaki, N | 1 |
| Faustman, EM; Seeley, MR | 1 |
| Akaike, M; Ohno, H; Omosu, M; Tsutsumi, S | 1 |
| Bochert, G; Meister, R; Neubert, D; Platzek, T | 1 |
| Collier, JM; Forsyth, CS; Frank, AA; Stoner, GD; Zeng, W | 1 |
| Bochert, G; Platzek, T | 1 |
| Gundlach, KK | 2 |
| Blaylock, BL; Gogal, RM; Holladay, SD; Sharova, L; Smith, BJ; Ward, DL | 1 |
| Koblitz, V; Schmitz, R; von Kreybig, T | 1 |
| Fritz, P; Mast, W; Wegner, G | 1 |
| Bartsch, H; Montesano, R | 1 |
| Alexandrov, VA | 1 |
| Berkowitz, J; Epstein, SS; Hasumi, K; Wilber, JH; Wilber, RG | 1 |
| Catalano, A; Huang, PH | 1 |
| Collier, JM; Forsyth, CS; Frank, AA; Heur, YH; Stoner, GD | 1 |
| Bochert, G; Neubert, D; Platzek, T; Rahm, U | 1 |
| Hata, S; Kusafuka, T; Nomura, T | 1 |
| Bopp, BA; Kesterson, JW; Sonders, RC | 1 |
| Granata, I; Spielmann, H; Tenschert, B; Vogel, R | 1 |
| Kuo, ML; Lin, JK | 1 |
| Bochert, G; Meister, R; Neubert, D; Pauli, B; Platzek, T | 1 |
| Nagao, T | 1 |
| Bossert, NL; Iannaccone, PM | 1 |
| Blankenburg, G; Bochert, G; Neubert, D; Platzek, T; Wiessler, M | 1 |
3 review(s) available for methylnitrosourea and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Embryotoxicity induced by alkylating agents: 7. Low dose prenatal-toxic risk estimation based on NOAEL risk factor approach, dose-response relationships, and DNA adducts using methylnitrosourea as a model compound.
Topics: Abnormalities, Drug-Induced; Algorithms; Alkylating Agents; Alkylation; Animals; DNA; DNA Damage; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Fetal Death; Guanine; Methylnitrosourea; Mice; Models, Theoretical; Pregnancy; Risk Factors; Toxicology | 1993 |
Mutagenic and carcinogenic N-nitroso compounds: possible environmental hazards.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Carcinogens; Cricetinae; Dimethylnitrosamine; Environmental Exposure; Female; Humans; Liver; Maternal-Fetal Exchange; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Mutagens; Nitrosamines; Nitroso Compounds; Pregnancy; Rats; Teratogens | 1976 |
Toxicological aspects of cyclamate and cyclohexylamine.
Topics: Abnormalities, Drug-Induced; Absorption; Adrenal Glands; Animals; Bacteria; Blood; Blood Glucose; Chick Embryo; Chromosome Aberrations; Cocarcinogenesis; Cricetinae; Cyclamates; Cyclohexylamines; Digestive System; Female; Germ Cells; Heart; Humans; In Vitro Techniques; Intestines; Kidney; Lethal Dose 50; Liver; Liver Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin; Macaca mulatta; Male; Methylnitrosourea; Mice; Mutagenicity Tests; Mutagens; Mutation; Neoplasms, Experimental; Pancreas; Pregnancy; Rabbits; Rats; Rats, Inbred Strains; Reproduction; Sympathomimetics; Testis; Thyroid Gland; Tissue Distribution; Urinary Bladder Neoplasms | 1986 |
28 other study(ies) available for methylnitrosourea and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Reduced birth defects caused by maternal immune stimulation in methylnitrosourea-exposed mice: association with placental improvement.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Drug Therapy, Combination; Ear, Inner; Endothelial Cells; Female; Immune System; Interferon-gamma; Limb Deformities, Congenital; Male; Maternal-Fetal Exchange; Methylnitrosourea; Mice; Placenta; Pregnancy; Trophoblasts | 2004 |
Placental improvement and reduced distal limb defects by maternal interferon-gamma injection in methylnitrosourea-exposed mice.
Topics: Abnormalities, Drug-Induced; Adjuvants, Immunologic; Animals; Endothelial Cells; Female; Gestational Age; Immune System; Injections, Intraperitoneal; Interferon-gamma; Lower Extremity Deformities, Congenital; Maternal-Fetal Exchange; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Placenta; Pregnancy; Random Allocation; Teratogens; Time Factors; Trophoblasts | 2005 |
Prebreeding maternal immunostimulation with Freund's complete adjuvant reduces placental damage and distal limb defects caused by methylnitrosourea.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Weight; Freund's Adjuvant; Limb Deformities, Congenital; Male; Maternal-Fetal Exchange; Methylnitrosourea; Mice; Mice, Inbred C57BL; Placenta; Pregnancy; Pregnancy Outcome; Pregnancy Rate | 2006 |
Teratogenic effects of methylnitrosourea on pregnant mice before implantation.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Embryonic Development; Female; Fetal Death; Fetus; Gestational Age; Methylnitrosourea; Mice; Mice, Inbred ICR; Nitrosourea Compounds; Pregnancy | 1984 |
N-nitrosophenacetin: its synthesis, characterization, mutagenicity, and teratogenicity.
Topics: Abnormalities, Drug-Induced; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Diethylnitrosamine; Dimethylnitrosamine; Lethal Dose 50; Methylnitronitrosoguanidine; Methylnitrosourea; Mutagenicity Tests; Mutagens; Nitrosamines; Rats; Rats, Inbred Strains; Spectrophotometry; Teratogens | 1984 |
Long-term effects of exposure to methylnitrosourea on blastocysts following transfer to surrogate female mice.
Topics: Abnormalities, Drug-Induced; Animals; Blastocyst; Embryo Transfer; Female; Methylnitrosourea; Mice; Mice, Inbred BALB C; Morula; Pregnancy; Pseudopregnancy | 1984 |
Experimentally induced cranial meningocele and cerebral microgyria.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Brain Diseases; Disease Models, Animal; Female; Meningocele; Methylnitrosourea; Nitrosourea Compounds; Pregnancy; Rats | 1982 |
Toxicity of four alkylating agents on in vitro rat embryo differentiation and development.
Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Forelimb; Methyl Methanesulfonate; Methylnitrosourea; Rats | 1995 |
Comparison of four spatial maze learning tests with methylnitrosourea-induced microcephaly rats.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Female; Learning Disabilities; Male; Methylnitrosourea; Microcephaly; Neuropsychological Tests; Organ Size; Rats; Rats, Sprague-Dawley; Spatial Behavior; Swimming | 1994 |
Ellagic acid embryoprotection in vitro: distribution and effects on DNA adduct formation.
Topics: Abnormalities, Drug-Induced; Animals; DNA Damage; Ellagic Acid; Embryo, Mammalian; Guanine; Methylnitrosourea; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Solubility; Teratogens; Yolk Sac | 1993 |
Embryotoxicity induced by alkylating agents: 10. Analysis of the combined teratogenic effects of methylnitrosourea and ethylmethanesulfonate in mice.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Bone and Bones; Dose-Response Relationship, Drug; Drug Synergism; Ethyl Methanesulfonate; Female; Methylnitrosourea; Mice; Pregnancy | 1995 |
Malformations of the temporo-mandibular joint in laboratory animals and in man.
Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Female; Glycine; Humans; Hydroxamic Acids; Infant, Newborn; Mercaptopurine; Methylnitrosourea; Mice; Mice, Inbred Strains; Pregnancy; Procarbazine; Rats; Rats, Sprague-Dawley; Temporomandibular Joint; Teratogens | 1999 |
Nonspecific stimulation of the maternal immune system. I. Effects On teratogen-induced fetal malformations.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adjuvants, Immunologic; Animals; BCG Vaccine; Cleft Palate; Crosses, Genetic; Female; Fetal Blood; Flow Cytometry; Foot; Freund's Adjuvant; Injections; Injections, Intraperitoneal; Limb Deformities, Congenital; Maternal-Fetal Exchange; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred ICR; Neural Tube Defects; Polychlorinated Dibenzodioxins; Pregnancy; Pyran Copolymer; Teratogens; Urethane; Valproic Acid | 2000 |
[Abnormal processes of vascularization of the head in relation to teratogenesis in various species of experimental animals].
Topics: Abnormalities, Drug-Induced; Animals; Blood Vessels; Female; Head; Methylnitrosourea; Mice; Pregnancy; Rats; Skull | 1977 |
[Teratogenic effect of N-methyl-N-nitrosourea on the brain anlage of rat embryos using autoradiographic methods (author's transl)].
Topics: Abnormalities, Drug-Induced; Anencephaly; Animals; Autoradiography; Brain; DNA; Female; Methylnitrosourea; Mitotic Index; Nitrosourea Compounds; Pregnancy; Rats; Regeneration; Time Factors | 1978 |
Some results and prospects of transplacental carcinogenesis studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Drug-Induced; Animals; Brain; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasms, Experimental; Nervous System Diseases; Nitrosourea Compounds; Organ Specificity; Placenta; Pregnancy; Rats | 1976 |
Pre- and postnatal toxicity induced in guinea pigs by N-nitrosomethylurea.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Birth Weight; Bronchopneumonia; Fatty Liver; Female; Fetal Death; Fetal Diseases; Fetus; Guinea Pigs; Male; Methylnitrosourea; Nitrosomethylurethane; Nitrosourea Compounds; Pregnancy | 1975 |
N-alkyl-N-nitrosourea induced secondary structural changes in DNA from rat embryos and fetal brains in vivo.
Topics: Abnormalities, Drug-Induced; Animals; Brain; DNA; Embryo, Mammalian; Ethylnitrosourea; Female; Fetus; Methylnitrosourea; Neoplasms, Experimental; Nucleic Acid Conformation; Pregnancy; Rats; Rats, Wistar | 1992 |
Ellagic acid protects rat embryos in culture from the embryotoxic effects of N-methyl-N-nitrosourea.
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Ectogenesis; Ellagic Acid; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Teratogens | 1992 |
Embryotoxicity induced by alkylating agents: 6. DNA adduct formation induced by methylnitrosourea in mouse embryos.
Topics: Abnormalities, Drug-Induced; Alkylation; Animals; DNA; DNA Repair; Embryo, Mammalian; Female; Guanine; Methylnitrosourea; Mice; Neoplasms, Experimental; Pregnancy | 1991 |
Suppression of developmental anomalies by maternal macrophages in mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Cell Survival; Congenital Abnormalities; Embryo, Mammalian; Female; Macrophage Activation; Macrophages; Maternal-Fetal Exchange; Methylnitrosourea; Mice; Mice, Inbred ICR; Mutation; Mycobacterium bovis; Pregnancy; Urethane | 1990 |
Abnormal development of mouse embryos exposed to methylnitrosourea before implantation.
Topics: Abnormalities, Drug-Induced; Animals; Blastocyst; Female; Gestational Age; Lethal Dose 50; Methylnitrosourea; Mice; Pregnancy | 1989 |
N-nitroso-N-2-fluorenylacetamide: a new direct-acting mutagen and teratogen.
Topics: 2-Acetylaminofluorene; Abnormalities, Drug-Induced; Adenosine; Amino Acids; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Chromatography, High Pressure Liquid; Cytidine; DNA Damage; Glutathione; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylnitronitrosoguanidine; Methylnitrosourea; Mutation; Nitroso Compounds; Nucleosides; Salmonella typhimurium; Spectrophotometry, Infrared | 1988 |
N-methyl-N-nitrosourea-induced malformations of the temporomandibular joint in rats.
Topics: Abnormalities, Drug-Induced; Animals; Ankylosis; Female; Mandibular Condyle; Methylnitrosourea; Rats; Rats, Inbred Strains; Temporomandibular Joint; Temporomandibular Joint Disorders | 1987 |
Embryotoxicity induced by alkylating agents: 5. Dose-response relationships of teratogenic effects of methylnitrosourea in mice.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fetus; Methylnitrosourea; Mice; Pregnancy; Teratogens | 1988 |
Frequency of congenital defects and dominant lethals in the offspring of male mice treated with methylnitrosourea.
Topics: Abnormalities, Drug-Induced; Animals; Drug Resistance; Female; Fetal Death; Fetal Diseases; Genes, Dominant; Genes, Lethal; Male; Methylnitrosourea; Mice; Mice, Inbred ICR; Pregnancy; Spermatogenesis; Spermatozoa; Stem Cells | 1987 |
Midgestational abnormalities associated with in vitro preimplantation N-methyl-N-nitrosourea exposure with subsequent transfer to surrogate mothers.
Topics: Abnormalities, Drug-Induced; Animals; Blastocyst; Dimethyl Sulfoxide; Embryo Transfer; Embryonic Development; Female; Fetal Death; Methylnitrosourea; Mice; Pregnancy | 1985 |
Embryotoxicity induced by alkylating agents: left-sided preponderance of paw malformations induced by acetoxymethyl-methylnitrosamine in mice.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Carcinogens; Dimethylnitrosamine; Female; Fingers; Foot Deformities, Congenital; Forelimb; Gestational Age; Hindlimb; Methylnitrosourea; Mice; Pregnancy | 1985 |