methylnitronitrosoguanidine has been researched along with Trypanosomiasis--African* in 1 studies
1 other study(ies) available for methylnitronitrosoguanidine and Trypanosomiasis--African
Article | Year |
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Resistance to Trypanosoma brucei in mice following inoculation of NTG-treated trypanosomes.
The alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (NTG) was tested as an attenuating agent for Trypanosoma brucei. Parasites were treated with 4 mcg/ml NTG and injected into mice at intervals of 7-14 days. Those mice surviving four injections of NTG-treated trypanosomes were later challenged and showed a 100% resistance to infection. A corresponding group of control mice showed a 6% resistance to infection. Topics: Animals; Female; Immunity, Innate; Immunization; Methylnitronitrosoguanidine; Mice; Trypanosoma brucei brucei; Trypanosomiasis, African | 1981 |