methylnitronitrosoguanidine and Foreign-Bodies

methylnitronitrosoguanidine has been researched along with Foreign-Bodies* in 2 studies

Other Studies

2 other study(ies) available for methylnitronitrosoguanidine and Foreign-Bodies

ArticleYear
[Comparative evaluation of the sensitivity to the carcinogenic action of N-methyl-N'-nitro-N-nitrosoguanidine of the epithelium of endophytic adenomatous-hyperplastic structures and of the epithelium of the gastric glands in rats].
    Eksperimental'naia onkologiia, 1988, Volume: 10, Issue:2

    The experiments carried on 107 rats have shown that the sensitivity of the epithelium of experimental adenomatous diverticuli of the stomach to the action of N-methyl-N'-nitro-N-nitrosoguanidine is lower than that of the gland epithelium of the organ.

    Topics: Adenocarcinoma; Animals; Diverticulum, Stomach; Epithelium; Female; Foreign Bodies; Gastric Mucosa; Hyperplasia; Methylnitronitrosoguanidine; Microscopy, Electron; Rats; Stomach; Stomach Neoplasms

1988
N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in experimental rat gastrocarcinogenesis: comparative sensibility to MNNG-carcinogenic action of the gland epithelium and the epithelium of experimental endophytic hyperplastic adenomatous structures.
    Experimental pathology, 1988, Volume: 35, Issue:1

    The comparative sensibility of the stomach gland epithelium and the epithelium of experimental gastric adenomatous diverticuli to carcinogenic action of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) was examined in experiments carried out in 107 rats; pathohistological techniques and electron-microscopic methods were applied. The epithelium of adenomatous diverticuli showed no signs of atypia or neoplasia in the course of MNNG-induced gastrocarcinogenesis. On the contrary, the epithelium of the gland cambial zone developed precancerous changes and adenocarcinomas. The formation of experimental diverticuli did not stimulate the development of rat stomach cancer.

    Topics: Adenoma; Animals; Diverticulitis; Diverticulum, Stomach; Female; Foreign Bodies; Gastric Mucosa; Methylnitronitrosoguanidine; Rats; Stomach Neoplasms

1988