methylmalonic acid has been researched along with Stroke in 7 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The level of total homocysteine (tHcy) that confers a risk of ischemic stroke is unsettled, and no prospective cohort studies have included sufficient elderly minority subjects." | 7.72 | Homocysteine and the risk of ischemic stroke in a triethnic cohort: the NOrthern MAnhattan Study. ( Allen, R; Anand, K; Boden-Albala, B; Lee, HS; Paik, MC; Sacco, RL; Stabler, S, 2004) |
| "Methylmalonic aciduria (MMA-uria) is seen in several inborn errors of metabolism (IEM) affecting intracellular cobalamin pathways." | 3.91 | ( Andréasson, M; Svenningsson, P; von Döbeln, U; Wedell, A; Zetterström, RH, 2019) |
| "In vivo characteristics of isatins [(18)F]-2 and [(18)F]-3 were studied and compared by μPET to previously described 1-[4-(2-[(18)F]fluoroethyl)benzyl]-5-(2-methoxymethylpyrrolidin-1-ylsulfonyl)isatin ([(18)F]-1) and to 2-(5-[(18)F]fluoropentyl)-2-methyl-malonic acid ([(18)F]ML-10) used as a reference radiotracer in a rat stroke model." | 3.83 | In Vivo Evaluation of Radiofluorinated Caspase-3/7 Inhibitors as Radiotracers for Apoptosis Imaging and Comparison with [18F]ML-10 in a Stroke Model in the Rat. ( Barré, L; Delamare, J; Dhilly, M; Fraser, BH; Greguric, I; Krause-Heuer, AM; Matesic, L; Médoc, M; Sobrio, F; Toutain, J; Touzani, O, 2016) |
| "The level of total homocysteine (tHcy) that confers a risk of ischemic stroke is unsettled, and no prospective cohort studies have included sufficient elderly minority subjects." | 3.72 | Homocysteine and the risk of ischemic stroke in a triethnic cohort: the NOrthern MAnhattan Study. ( Allen, R; Anand, K; Boden-Albala, B; Lee, HS; Paik, MC; Sacco, RL; Stabler, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andréasson, M | 1 |
| Zetterström, RH | 1 |
| von Döbeln, U | 1 |
| Wedell, A | 1 |
| Svenningsson, P | 1 |
| Médoc, M | 1 |
| Dhilly, M | 1 |
| Matesic, L | 1 |
| Toutain, J | 1 |
| Krause-Heuer, AM | 1 |
| Delamare, J | 1 |
| Fraser, BH | 1 |
| Touzani, O | 1 |
| Barré, L | 1 |
| Greguric, I | 1 |
| Sobrio, F | 1 |
| Pascoe, MC | 1 |
| Linden, T | 1 |
| Reshef, A | 1 |
| Shirvan, A | 1 |
| Waterhouse, RN | 1 |
| Grimberg, H | 1 |
| Levin, G | 1 |
| Cohen, A | 1 |
| Ulysse, LG | 1 |
| Friedman, G | 1 |
| Antoni, G | 1 |
| Ziv, I | 1 |
| Kara, N | 1 |
| Senes, M | 1 |
| Coskun, O | 1 |
| Inan, L | 1 |
| Saydam, G | 1 |
| Yucel, D | 1 |
| Sacco, RL | 1 |
| Anand, K | 1 |
| Lee, HS | 1 |
| Boden-Albala, B | 1 |
| Stabler, S | 1 |
| Allen, R | 1 |
| Paik, MC | 1 |
| Chakrapani, A | 1 |
| Sivakumar, P | 1 |
| McKiernan, PJ | 1 |
| Leonard, JV | 1 |
7 other studies available for methylmalonic acid and Stroke
| Article | Year |
|---|---|
Topics: Aged; Dementia; Humans; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Mutation; Parkinson Dis | 2019 |
In Vivo Evaluation of Radiofluorinated Caspase-3/7 Inhibitors as Radiotracers for Apoptosis Imaging and Comparison with [18F]ML-10 in a Stroke Model in the Rat.
Topics: Animals; Apoptosis; Caspase 3; Caspase 7; Caspase Inhibitors; Disease Models, Animal; Isatin; Male; | 2016 |
Folate and MMA predict cognitive impairment in elderly stroke survivors: A cross sectional study.
Topics: Aged; Aged, 80 and over; Cognition Disorders; Cross-Sectional Studies; Female; Folic Acid; Folic Aci | 2016 |
Molecular imaging of neurovascular cell death in experimental cerebral stroke by PET.
Topics: Animals; Apoptosis; Disease Models, Animal; Male; Methylmalonic Acid; Molecular Probe Techniques; Ne | 2008 |
Urinary methylmalonic acid levels in patients with acute ischemic stroke.
Topics: Aged; Aged, 80 and over; Brain Ischemia; Creatinine; Female; Folic Acid; Homocysteine; Humans; Male; | 2009 |
Homocysteine and the risk of ischemic stroke in a triethnic cohort: the NOrthern MAnhattan Study.
Topics: Aged; Black People; Cohort Studies; Female; Hispanic or Latino; Homocysteine; Humans; Male; Methylma | 2004 |
Metabolic stroke in methylmalonic acidemia five years after liver transplantation.
Topics: Age of Onset; Child, Preschool; Female; Humans; Liver Transplantation; Metabolism, Inborn Errors; Me | 2002 |