methylmalonic acid has been researched along with Renal Insufficiency in 6 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylmalonic acid was previously considered as major neurotoxin in methylmalonic acidurias." | 2.43 | Methylmalonic acid--an endogenous toxin? ( Kölker, S; Okun, JG, 2005) |
| "He had a family history of primary pulmonary hypertension in a sister." | 1.51 | Primary Pulmonary Hypertension Associated with Asymptomatic Methylmalonic Aciduria in a Child. ( Chioukh, FZ; Monastiri, K, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chioukh, FZ | 1 |
| Monastiri, K | 1 |
| Affonso, AC | 1 |
| Machado, DG | 1 |
| Malgarin, F | 1 |
| Fraga, DB | 1 |
| Ghedim, F | 1 |
| Zugno, A | 1 |
| Streck, EL | 1 |
| Schuck, PF | 1 |
| Ferreira, GC | 1 |
| Solomon, LR | 1 |
| Bross, MH | 1 |
| Soch, K | 1 |
| Smith-Knuppel, T | 1 |
| Kölker, S | 1 |
| Okun, JG | 1 |
| Baumgarter, ER | 1 |
| Viardot, C | 1 |
1 review available for methylmalonic acid and Renal Insufficiency
| Article | Year |
|---|---|
Methylmalonic acid--an endogenous toxin?
Topics: Energy Metabolism; Humans; Metabolism, Inborn Errors; Methylmalonic Acid; Mitochondria; Neurotoxins; | 2005 |
5 other studies available for methylmalonic acid and Renal Insufficiency
| Article | Year |
|---|---|
Primary Pulmonary Hypertension Associated with Asymptomatic Methylmalonic Aciduria in a Child.
Topics: Amino Acid Metabolism, Inborn Errors; Cyanosis; Familial Primary Pulmonary Hypertension; Fatal Outco | 2019 |
Increased susceptibility of brain acetylcholinesterase activity to methylmalonate in young rats with renal failure.
Topics: Acetylcholinesterase; Amino Acid Metabolism, Inborn Errors; Analysis of Variance; Animals; Brain; Ch | 2013 |
Functional cobalamin (vitamin B12) deficiency: role of advanced age and disorders associated with increased oxidative stress.
Topics: Aged; Aged, 80 and over; Aging; Alcohol Drinking; Connecticut; Diabetes Mellitus; Dietary Supplement | 2015 |
Anemia in older persons.
Topics: Aged; Algorithms; Anemia; Deficiency Diseases; Erythrocyte Indices; Female; Ferritins; Folic Acid; H | 2010 |
Long-term follow-up of 77 patients with isolated methylmalonic acidaemia.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cobamides; Creatin | 1995 |