methylmalonic acid has been researched along with Pancytopenia in 3 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 7-week-old infant with methylmalonic acidemia had pancytopenia and hypoplastic bone marrow." | 7.66 | Inhibition of bone marrow stem cell growth in vitro by methylmalonic acid: a mechanism for pancytopenia in a patient with methylmalonic acidemia. ( Fracassa, M; Inoue, S; Krieger, I; Ottenbreit, MJ; Ravindranath, Y; Sarnaik, A, 1981) |
| "A 7-week-old infant with methylmalonic acidemia had pancytopenia and hypoplastic bone marrow." | 3.66 | Inhibition of bone marrow stem cell growth in vitro by methylmalonic acid: a mechanism for pancytopenia in a patient with methylmalonic acidemia. ( Fracassa, M; Inoue, S; Krieger, I; Ottenbreit, MJ; Ravindranath, Y; Sarnaik, A, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ratschmann, R | 1 |
| Minkov, M | 1 |
| Kis, A | 1 |
| Hung, C | 1 |
| Rupar, T | 1 |
| Mühl, A | 1 |
| Fowler, B | 1 |
| Nexo, E | 1 |
| Bodamer, OA | 1 |
| Inoue, S | 1 |
| Krieger, I | 1 |
| Sarnaik, A | 1 |
| Ravindranath, Y | 1 |
| Fracassa, M | 1 |
| Ottenbreit, MJ | 1 |
| Barshop, BA | 1 |
| Wolff, J | 1 |
| Nyhan, WL | 1 |
| Yu, A | 1 |
| Prodanos, C | 1 |
| Jones, G | 1 |
| Sweetman, L | 1 |
| Leslie, J | 1 |
| Holm, J | 1 |
| Green, R | 1 |
3 other studies available for methylmalonic acid and Pancytopenia
| Article | Year |
|---|---|
Transcobalamin II deficiency at birth.
Topics: Child, Preschool; Disease Progression; Female; Humans; Infant; Methylmalonic Acid; Pancytopenia; Tra | 2009 |
Inhibition of bone marrow stem cell growth in vitro by methylmalonic acid: a mechanism for pancytopenia in a patient with methylmalonic acidemia.
Topics: Bone Marrow; Bone Marrow Cells; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Infant; Malon | 1981 |
Transcobalamin II deficiency presenting with methylmalonic aciduria and homocystinuria and abnormal absorption of cobalamin.
Topics: Failure to Thrive; Female; Homocystinuria; Humans; Infant; Intestinal Absorption; Malonates; Methylm | 1990 |