methylmalonic acid has been researched along with Neurodegenerative Diseases in 2 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Melo, DR | 1 |
| Kowaltowski, AJ | 1 |
| Wajner, M | 1 |
| Castilho, RF | 1 |
| Morath, MA | 1 |
| Okun, JG | 1 |
| Müller, IB | 1 |
| Sauer, SW | 1 |
| Hörster, F | 1 |
| Hoffmann, GF | 1 |
| Kölker, S | 1 |
2 reviews available for methylmalonic acid and Neurodegenerative Diseases
| Article | Year |
|---|---|
Mitochondrial energy metabolism in neurodegeneration associated with methylmalonic acidemia.
Topics: Amino Acid Metabolism, Inborn Errors; Energy Metabolism; Humans; Methylmalonic Acid; Mitochondria; N | 2011 |
Neurodegeneration and chronic renal failure in methylmalonic aciduria--a pathophysiological approach.
Topics: Animals; Brain; Dicarboxylic Acids; Energy Metabolism; Humans; Kidney; Kidney Failure, Chronic; Meth | 2008 |