methylmalonic acid has been researched along with Muscle Spasticity in 2 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keller, R | 1 |
| Chrastina, P | 1 |
| Pavlíková, M | 1 |
| Gouveia, S | 2 |
| Ribes, A | 1 |
| Kölker, S | 2 |
| Blom, HJ | 1 |
| Baumgartner, MR | 2 |
| Bártl, J | 1 |
| Dionisi-Vici, C | 2 |
| Gleich, F | 2 |
| Morris, AA | 2 |
| Kožich, V | 2 |
| Huemer, M | 2 |
| Barić, I | 1 |
| Ben-Omran, T | 1 |
| Blasco-Alonso, J | 2 |
| Bueno Delgado, MA | 1 |
| Carducci, C | 1 |
| Cassanello, M | 1 |
| Cerone, R | 2 |
| Couce, ML | 2 |
| Crushell, E | 2 |
| Delgado Pecellin, C | 1 |
| Dulin, E | 1 |
| Espada, M | 1 |
| Ferino, G | 1 |
| Fingerhut, R | 1 |
| Garcia Jimenez, I | 1 |
| Gonzalez Gallego, I | 1 |
| González-Irazabal, Y | 1 |
| Gramer, G | 1 |
| Juan Fita, MJ | 1 |
| Karg, E | 1 |
| Klein, J | 1 |
| Konstantopoulou, V | 2 |
| la Marca, G | 1 |
| Leão Teles, E | 1 |
| Leuzzi, V | 1 |
| Lilliu, F | 1 |
| Lopez, RM | 1 |
| Lund, AM | 2 |
| Mayne, P | 1 |
| Meavilla, S | 1 |
| Moat, SJ | 1 |
| Okun, JG | 1 |
| Pasquini, E | 1 |
| Pedron-Giner, CC | 1 |
| Racz, GZ | 1 |
| Ruiz Gomez, MA | 2 |
| Vilarinho, L | 1 |
| Yahyaoui, R | 1 |
| Zerjav Tansek, M | 1 |
| Zetterström, RH | 1 |
| Zeyda, M | 1 |
| Diodato, D | 1 |
| Martinelli, D | 1 |
| Olivieri, G | 1 |
| Blom, H | 1 |
| Seifert, B | 1 |
| Froese, DS | 1 |
| Martin, CA | 1 |
| Baethmann, M | 1 |
| Ballhausen, D | 1 |
| Boy, N | 1 |
| Bueno, M | 1 |
| Burgos Peláez, R | 1 |
| Chabrol, B | 1 |
| Chapman, KA | 1 |
| Dalmau Serra, J | 1 |
| Diogo, L | 1 |
| Ficicioglu, C | 1 |
| García Jimenez, MC | 1 |
| García Silva, MT | 1 |
| Gaspar, AM | 1 |
| Gautschi, M | 1 |
| González-Lamuño, D | 1 |
| Grünewald, S | 1 |
| Hendriksz, C | 1 |
| Janssen, MCH | 1 |
| Jesina, P | 1 |
| Koch, J | 1 |
| Lavigne, C | 1 |
| Martins, EG | 1 |
| Meavilla Olivas, S | 1 |
| Mention, K | 1 |
| Mochel, F | 1 |
| Mundy, H | 1 |
| Murphy, E | 1 |
| Paquay, S | 1 |
| Pedrón-Giner, C | 1 |
| Santra, S | 1 |
| Schiff, M | 1 |
| Schwartz, IV | 1 |
| Scholl-Bürgi, S | 1 |
| Servais, A | 1 |
| Skouma, A | 1 |
| Tran, C | 1 |
| Vives Piñera, I | 1 |
| Walter, J | 1 |
| Weisfeld-Adams, J | 1 |
2 other studies available for methylmalonic acid and Muscle Spasticity
| Article | Year |
|---|---|
Newborn screening for homocystinurias: Recent recommendations versus current practice.
Topics: Acetylcarnitine; Amino Acid Metabolism, Inborn Errors; Carnitine; Female; Glycine N-Methyltransferas | 2019 |
Phenotype, treatment practice and outcome in the cobalamin-dependent remethylation disorders and MTHFR deficiency: Data from the E-HOD registry.
Topics: Adolescent; Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cros | 2019 |