Page last updated: 2024-10-17

methylmalonic acid and Mucositis

methylmalonic acid has been researched along with Mucositis in 1 studies

Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.

Mucositis: An INFLAMMATION of the MUCOSA with burning or tingling sensation. It is characterized by atrophy of the squamous EPITHELIUM, vascular damage, inflammatory infiltration, and ulceration. It usually occurs at the mucous lining of the MOUTH, the GASTROINTESTINAL TRACT or the airway due to chemical irritations, CHEMOTHERAPY, or radiation therapy (RADIOTHERAPY).

Research Excerpts

ExcerptRelevanceReference
" Weight and methylmalonic acid (MMA) level were predictive of pharmacokinetic (PK) variability."1.35A population pharmacokinetic and pharmacodynamic evaluation of pralatrexate in patients with relapsed or refractory non-Hodgkin's or Hodgkin's lymphoma. ( Duffull, SB; Fleisher, M; Hamlin, P; Horwitz, S; Mould, DR; Neylon, E; O'Connor, OA; Saunders, ME; Sirotnak, F; Sweeney, K, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mould, DR1
Sweeney, K1
Duffull, SB1
Neylon, E1
Hamlin, P1
Horwitz, S1
Sirotnak, F1
Fleisher, M1
Saunders, ME1
O'Connor, OA1

Other Studies

1 other study available for methylmalonic acid and Mucositis

ArticleYear
A population pharmacokinetic and pharmacodynamic evaluation of pralatrexate in patients with relapsed or refractory non-Hodgkin's or Hodgkin's lymphoma.
    Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:2

    Topics: Adult; Aged; Aminopterin; Antineoplastic Agents; Area Under Curve; Biomarkers; Body Size; Drug Admin

2009