methylmalonic acid has been researched along with Metabolic Diseases in 6 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylmalonic aciduria (MMA) is a common one of the congenital disorders of organic acids metabolism." | 2.73 | [Clinical studies on fifty-seven Chinese patients with combined methylmalonic aciduria and homocysteinemia]. ( Dong, JH; Jiang, YW; Liu, P; Qin, J; Song, JQ; Wang, LF; Wu, XR; Yan, R; Yang, YL; Zhang, Y; Zhang, YH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heringer, J | 1 |
| Valayannopoulos, V | 1 |
| Lund, AM | 1 |
| Wijburg, FA | 1 |
| Freisinger, P | 1 |
| Barić, I | 1 |
| Baumgartner, MR | 1 |
| Burgard, P | 1 |
| Burlina, AB | 1 |
| Chapman, KA | 1 |
| I Saladelafont, EC | 1 |
| Karall, D | 1 |
| Mühlhausen, C | 1 |
| Riches, V | 1 |
| Schiff, M | 1 |
| Sykut-Cegielska, J | 1 |
| Walter, JH | 1 |
| Zeman, J | 1 |
| Chabrol, B | 1 |
| Kölker, S | 1 |
| Yang, Y | 1 |
| Yao, Z | 1 |
| Song, J | 1 |
| Hasegawa, Y | 1 |
| Kimura, M | 1 |
| Yamaguchi, S | 1 |
| Jiang, Y | 1 |
| Qin, J | 2 |
| Wu, X | 1 |
| Zhang, Y | 1 |
| Song, JQ | 1 |
| Liu, P | 1 |
| Yan, R | 1 |
| Dong, JH | 1 |
| Yang, YL | 1 |
| Wang, LF | 1 |
| Jiang, YW | 1 |
| Zhang, YH | 1 |
| Wu, XR | 1 |
| Piccardo, M | 1 |
| Tassara, F | 1 |
| Vico, L | 1 |
| Rozen, R | 1 |
| Buhl, S | 1 |
| Mohyuddin, F | 1 |
| Caillibot, V | 1 |
| Scriver, CR | 2 |
| Lemieux, B | 1 |
| Auray-Blais, C | 1 |
| Giguère, R | 1 |
1 review available for methylmalonic acid and Metabolic Diseases
| Article | Year |
|---|---|
[Some clinical and therapeutic aspects of organico-acidemia and organico-aciduria].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Butyrates; Humans; Maple Syrup Urine Disease; Met | 1977 |
1 trial available for methylmalonic acid and Metabolic Diseases
| Article | Year |
|---|---|
[Clinical studies on fifty-seven Chinese patients with combined methylmalonic aciduria and homocysteinemia].
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Anemia; Carnitine; Child; Child, Preschool; | 2007 |
4 other studies available for methylmalonic acid and Metabolic Diseases
| Article | Year |
|---|---|
Impact of age at onset and newborn screening on outcome in organic acidurias.
Topics: Adolescent; Adult; Age of Onset; Amino Acid Metabolism, Inborn Errors; Amino Acid Transport Disorder | 2016 |
Outcome of organic acidurias in China.
Topics: Child; Child, Preschool; China; Humans; Infant; Infant, Newborn; Metabolic Diseases; Methylmalonic A | 2008 |
Evaluation of metabolic pathway activity in cultured skin fibroblasts and blood leukocytes.
Topics: Acidosis; Adult; Cells, Cultured; Child; Child, Preschool; Female; Fibroblasts; Galactose; Galactose | 1977 |
Neuroblastoma screening: the Canadian experience.
Topics: Amino Acids; Canada; Chromatography, Thin Layer; False Positive Reactions; Homovanillic Acid; Humans | 1989 |