methylmalonic acid has been researched along with Malabsorption Syndromes in 11 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Malabsorption Syndromes: General term for a group of MALNUTRITION syndromes caused by failure of normal INTESTINAL ABSORPTION of nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 7-month-old boy presented with vomiting and failure to thrive associated with proteinuria, methylmalonic aciduria and macrocytosis, but without anaemia." | 3.67 | Selective vitamin B12 malabsorption without anaemia but with profound failure to thrive. ( Auchterlonie, IA; Campbell, AG; Thom, H, 1985) |
| "Diagnosis of vitamin B12 deficiency is typically based on measurement of serum vitamin B12 levels; however, about 50 percent of patients with subclinical disease have normal B12 levels." | 2.42 | Vitamin B12 deficiency. ( Brown, DL; Oh, R, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kook, PH | 2 |
| Reusch, CE | 1 |
| Hersberger, M | 2 |
| Sukumar, N | 1 |
| Saravanan, P | 1 |
| Watkins, D | 1 |
| Rosenblatt, DS | 1 |
| Watanabe, T | 1 |
| Hoshi, K | 1 |
| Zhang, C | 1 |
| Ishida, Y | 1 |
| Sakata, I | 1 |
| Oh, R | 1 |
| Brown, DL | 1 |
| Campbell, CD | 1 |
| Ganesh, J | 1 |
| Ficicioglu, C | 1 |
| Joosten, E | 1 |
| Pelemans, W | 1 |
| Devos, P | 1 |
| Lesaffre, E | 1 |
| Goossens, W | 1 |
| Criel, A | 1 |
| Verhaeghe, R | 1 |
| Rosenberg, LE | 1 |
| Fyfe, JC | 1 |
| Giger, U | 1 |
| Hall, CA | 1 |
| Jezyk, PF | 1 |
| Klumpp, SA | 1 |
| Levine, JS | 1 |
| Patterson, DF | 1 |
| Auchterlonie, IA | 1 |
| Thom, H | 1 |
| Campbell, AG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Oral Vitamin B12 Administration for Vitamin B12 Deficiency After Total Gastrectomy[NCT00699478] | Phase 2 | 30 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for methylmalonic acid and Malabsorption Syndromes
| Article | Year |
|---|---|
Vitamin B12 deficiency.
Topics: Humans; Malabsorption Syndromes; Mental Disorders; Methylmalonic Acid; Nervous System Diseases; Prac | 2003 |
Vitamin-responsive inherited metabolic disorders.
Topics: Adolescent; Adult; Anemia, Megaloblastic; Avitaminosis; Biological Transport; Biotin; Carrier Protei | 1976 |
9 other studies available for methylmalonic acid and Malabsorption Syndromes
| Article | Year |
|---|---|
Prospective long-term evaluation of parenteral hydroxocobalamin supplementation in juvenile beagles with selective intestinal cobalamin malabsorption (Imerslund-Gräsbeck syndrome).
Topics: Anemia, Megaloblastic; Animals; Creatinine; Dog Diseases; Dogs; Drug Administration Schedule; Female | 2018 |
Daily oral cyanocobalamin supplementation in Beagles with hereditary cobalamin malabsorption (Imerslund-Gräsbeck syndrome) maintains normal clinical and cellular cobalamin status.
Topics: Administration, Oral; Anemia, Megaloblastic; Animals; Dog Diseases; Dogs; Female; Malabsorption Synd | 2019 |
Investigating vitamin B12 deficiency.
Topics: Adult; Aged; Biomarkers; Female; Folic Acid; Health Surveys; Homocysteine; Humans; Infant; Malabsorp | 2019 |
Inborn errors of cobalamin absorption and metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Anemia, Megaloblastic; Cobamides; Homocysteine; Humans; Hyperh | 2011 |
Hyperammonaemia due to cobalamin malabsorption in a cat with exocrine pancreatic insufficiency.
Topics: Animals; Cat Diseases; Cats; Exocrine Pancreatic Insufficiency; Hyperammonemia; Malabsorption Syndro | 2012 |
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; | 2005 |
Cobalamin absorption and serum homocysteine and methylmalonic acid in elderly subjects with low serum cobalamin.
Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Female; Homocysteine; Humans; Intestinal Absorptio | 1993 |
Inherited selective intestinal cobalamin malabsorption and cobalamin deficiency in dogs.
Topics: Animals; Dog Diseases; Dogs; Female; Genes, Recessive; Ileum; Intrinsic Factor; Malabsorption Syndro | 1991 |
Selective vitamin B12 malabsorption without anaemia but with profound failure to thrive.
Topics: Child, Preschool; Dietary Proteins; Humans; Infant; Malabsorption Syndromes; Male; Methylmalonic Aci | 1985 |