methylmalonic acid has been researched along with MODS in 1 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to identify the causative genetic lesion in two apparently unrelated newborns having lethal lactic acidosis, multi-organ failure and congenital malformations including interrupted aortic arch, who exhibited mild methylmalonic aciduria, combined mitochondrial respiratory chain deficiency, and marked muscle mitochondrial DNA depletion." | 3.76 | Marked mitochondrial DNA depletion associated with a novel SUCLG1 gene mutation resulting in lethal neonatal acidosis, multi-organ failure, and interrupted aortic arch. ( Andreu, AL; Arenas, J; Arroyo, I; Bornstein, B; Gallardo, E; Garesse, R; Marti, R; Martin, MA; Martinez-Pardo, M; Merinero, B; Moran, MJ; Perez-Jurado, LA; Rivera, H; Ruiz-Sala, P; Serra-Suhe, C; Ugalde, C; Ugarte, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rivera, H | 1 |
| Merinero, B | 1 |
| Martinez-Pardo, M | 1 |
| Arroyo, I | 1 |
| Ruiz-Sala, P | 1 |
| Bornstein, B | 1 |
| Serra-Suhe, C | 1 |
| Gallardo, E | 1 |
| Marti, R | 1 |
| Moran, MJ | 1 |
| Ugalde, C | 1 |
| Perez-Jurado, LA | 1 |
| Andreu, AL | 1 |
| Garesse, R | 1 |
| Ugarte, M | 1 |
| Arenas, J | 1 |
| Martin, MA | 1 |
1 other study available for methylmalonic acid and MODS
| Article | Year |
|---|---|
Marked mitochondrial DNA depletion associated with a novel SUCLG1 gene mutation resulting in lethal neonatal acidosis, multi-organ failure, and interrupted aortic arch.
Topics: Acidosis; Aorta, Thoracic; DNA, Mitochondrial; Fatal Outcome; Female; Genetic Diseases, Inborn; Huma | 2010 |