methylmalonic acid has been researched along with Insulin Resistance in 4 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vitamin B12 deficiency is common in certain populations, such as in India, where there is also a rising prevalence of Type 2 diabetes, obesity and their complications." | 2.50 | The role of the one-carbon cycle in the developmental origins of Type 2 diabetes and obesity. ( Finer, S; Hitman, G; Saravanan, P; Yajnik, C, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bjune, MS | 1 |
| Lindquist, C | 1 |
| Hallvardsdotter Stafsnes, M | 1 |
| Bjørndal, B | 1 |
| Bruheim, P | 1 |
| Aloysius, TA | 1 |
| Nygård, O | 1 |
| Skorve, J | 1 |
| Madsen, L | 1 |
| Dankel, SN | 1 |
| Berge, RK | 1 |
| Li, Z | 1 |
| Gueant-Rodriguez, RM | 1 |
| Quilliot, D | 1 |
| Sirveaux, MA | 1 |
| Meyre, D | 1 |
| Gueant, JL | 1 |
| Brunaud, L | 1 |
| Finer, S | 1 |
| Saravanan, P | 1 |
| Hitman, G | 1 |
| Yajnik, C | 1 |
| Yajnik, CS | 1 |
| Deshpande, SS | 1 |
| Jackson, AA | 1 |
| Refsum, H | 1 |
| Rao, S | 1 |
| Fisher, DJ | 1 |
| Bhat, DS | 1 |
| Naik, SS | 1 |
| Coyaji, KJ | 1 |
| Joglekar, CV | 1 |
| Joshi, N | 1 |
| Lubree, HG | 1 |
| Deshpande, VU | 1 |
| Rege, SS | 1 |
| Fall, CH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Vitamins Status on Severe Obesity Related Complications[NCT02663388] | 20,000 participants (Anticipated) | Observational [Patient Registry] | 2016-01-31 | Recruiting | |||
| Supplementation of Vitamin B12 in Pregnancy and Postpartum on Growth and Cognitive Functioning in Early Childhood: A Randomized, Placebo Controlled Trial[NCT03071666] | Phase 2/Phase 3 | 800 participants (Actual) | Interventional | 2017-03-27 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for methylmalonic acid and Insulin Resistance
| Article | Year |
|---|---|
The role of the one-carbon cycle in the developmental origins of Type 2 diabetes and obesity.
Topics: Adiposity; Carbon Cycle; Diabetes Mellitus, Type 2; Environmental Exposure; Female; Fetal Developmen | 2014 |
3 other studies available for methylmalonic acid and Insulin Resistance
| Article | Year |
|---|---|
Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats.
Topics: Animals; Fatty Acids; Hydroxybutyrates; Insulin Resistance; Male; Methylmalonic Acid; Mitochondria, | 2021 |
Folate and vitamin B12 status is associated with insulin resistance and metabolic syndrome in morbid obesity.
Topics: Adult; Body Mass Index; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Insulin Resistance; | 2018 |
Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study.
Topics: Adipose Tissue; Anthropometry; Body Composition; Body Mass Index; Child; Female; Folic Acid; Homocys | 2008 |