methylmalonic acid has been researched along with Hyper IgD Syndrome in 1 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with these inborn errors of metabolism are thought to be at risk for CoQ(10) depletion either by direct inhibition of the proximal pathway of CoQ(10) synthesis (MVA) or indirectly by inhibition of mitochondrial energy metabolism (MMA)." | 1.35 | Coenzyme Q(10) is decreased in fibroblasts of patients with methylmalonic aciduria but not in mevalonic aciduria. ( Baumgartner, ER; Haas, D; Hoffmann, GF; Hörster, F; Menke, T; Niklowitz, P; Okun, JG; Prasad, C; Rodenburg, RJ, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haas, D | 1 |
| Niklowitz, P | 1 |
| Hörster, F | 1 |
| Baumgartner, ER | 1 |
| Prasad, C | 1 |
| Rodenburg, RJ | 1 |
| Hoffmann, GF | 1 |
| Menke, T | 1 |
| Okun, JG | 1 |
1 other study available for methylmalonic acid and Hyper IgD Syndrome
| Article | Year |
|---|---|
Coenzyme Q(10) is decreased in fibroblasts of patients with methylmalonic aciduria but not in mevalonic aciduria.
Topics: Case-Control Studies; Cells, Cultured; Down-Regulation; Female; Fibroblasts; Humans; Metabolism, Inb | 2009 |