methylmalonic acid has been researched along with Epilepsy, Tonic-Clonic in 2 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aikoh, H | 1 |
| Sasaki, M | 1 |
| Sugai, K | 1 |
| Yoshida, H | 1 |
| Sakuragawa, N | 1 |
| O'Brien, DP | 1 |
| Barshop, BA | 1 |
| Faunt, KK | 1 |
| Johnson, GC | 1 |
| Gibson, KM | 1 |
| Shelton, GD | 1 |
2 other studies available for methylmalonic acid and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Effective immunoglobulin therapy for brief tonic seizures in methylmalonic acidemia.
Topics: Amino Acid Metabolism, Inborn Errors; Brain; Electroencephalography; Epilepsy, Tonic-Clonic; Humans; | 1997 |
Malonic aciduria in Maltese dogs: normal methylmalonic acid concentrations and malonyl-CoA decarboxylase activity in fibroblasts.
Topics: Animals; Carboxy-Lyases; Diet; Dog Diseases; Dogs; Epilepsy, Tonic-Clonic; Female; Fibroblasts; Malo | 1999 |