Page last updated: 2024-10-17

methylmalonic acid and Dysesthesia

methylmalonic acid has been researched along with Dysesthesia in 6 studies

Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.

Research Excerpts

ExcerptRelevanceReference
" Characteristic features in such patients included paresthesia, sensory loss, ataxia, dementia, and psychiatric disorders; longstanding neurologic symptoms without anemia; normal white-cell and platelet counts and serum bilirubin and lactate dehydrogenase levels; and markedly elevated serum concentrations of methylmalonic acid and total homocysteine."3.67Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. ( Allen, RH; Brust, JC; Garrett, TJ; Healton, EB; Lindenbaum, J; Marcell, PD; Podell, ER; Savage, DG; Stabler, SP, 1988)
"Vegetarians have Vitamin B12 deficiency and are more prone to developing neuropsychiatric and neurological problems."1.46Neuropsychiatric and neurological problems among Vitamin B12 deficient young vegetarians. ( Baig, M; Kapoor, A; Karmani, H; Memon, AS; Tunio, SA, 2017)
"Vitamin B12 deficiency is common, with most patients lacking classic features of advanced severe deficiency."1.31Reversible myelopathy in a 34-year-old man with vitamin B12 deficiency. ( Harper, CM; Payne, TA; Pittock, SJ, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kapoor, A1
Baig, M1
Tunio, SA1
Memon, AS1
Karmani, H1
Duque, MA1
Kresak, JL1
Falchook, A1
Harris, NS1
Tweet, MS1
Polga, KM1
Stabler, SP2
Pittock, SJ1
Payne, TA1
Harper, CM1
Lindenbaum, J1
Healton, EB1
Savage, DG1
Brust, JC1
Garrett, TJ1
Podell, ER1
Marcell, PD1
Allen, RH1

Reviews

1 review available for methylmalonic acid and Dysesthesia

ArticleYear
Clinical practice. Vitamin B12 deficiency.
    The New England journal of medicine, 2013, Jan-10, Volume: 368, Issue:2

    Topics: Administration, Oral; Anemia, Pernicious; Child; Child Nutrition Disorders; Diagnostic Errors; Femal

2013

Other Studies

5 other studies available for methylmalonic acid and Dysesthesia

ArticleYear
Neuropsychiatric and neurological problems among Vitamin B12 deficient young vegetarians.
    Neurosciences (Riyadh, Saudi Arabia), 2017, Volume: 22, Issue:3

    Topics: Adult; Case-Control Studies; Comorbidity; Cross-Sectional Studies; Depression; Female; Folic Acid; H

2017
Nitrous Oxide Abuse and Vitamin B12 Action in a 20-Year-Old Woman: A Case Report.
    Laboratory medicine, 2015,Fall, Volume: 46, Issue:4

    Topics: Adult; Demyelinating Diseases; Female; Humans; Methylmalonic Acid; Nitrous Oxide; Paresthesia; Spina

2015
44-year-old man with shortness of breath, fatigue, and paresthesia.
    Mayo Clinic proceedings, 2010, Volume: 85, Issue:12

    Topics: Adult; Anemia, Pernicious; Blood Cell Count; Diagnosis, Differential; Dyspnea; Fatigue; Humans; Male

2010
Reversible myelopathy in a 34-year-old man with vitamin B12 deficiency.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:3

    Topics: Adult; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; Male; Methylmalonic Acid; Parest

2002
Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis.
    The New England journal of medicine, 1988, Jun-30, Volume: 318, Issue:26

    Topics: Adolescent; Adult; Aged; Anemia; Anemia, Megaloblastic; Ataxia; Erythrocyte Indices; Erythrocytes; F

1988