methylmalonic acid has been researched along with Deficiency Disease, Ornithine Carbamoyltransferase in 9 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylmalonic acidemia (MMA) was most common (74 cases), followed by propionic acidemia (23 cases), ornitine transcarbamylase deficiency (22 cases), and multiple carboxylase deficiency (15 cases)." | 1.33 | Clinical onset and prognosis of Asian children with organic acidemias, as detected by analysis of urinary organic acids using GC/MS, instead of mass screening. ( Hasegawa, Y; Hori, D; Kimura, M; Verma, IC; Yamaguchi, S; Yang, Y, 2005) |
| " In addition a dose-response effect of alanine was observed." | 1.27 | Alanine decreases the protein requirements of infants with inborn errors of amino acid metabolism. ( Algert, S; Kelts, DG; Nyhan, WL; Prodanos, C; Wolff, JA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hori, D | 1 |
| Hasegawa, Y | 1 |
| Kimura, M | 1 |
| Yang, Y | 1 |
| Verma, IC | 1 |
| Yamaguchi, S | 1 |
| Huang, HP | 2 |
| Chien, YH | 1 |
| Huang, LM | 1 |
| Ni, YH | 1 |
| Chang, MH | 1 |
| Ho, MC | 1 |
| Lee, PH | 1 |
| Hwu, WL | 1 |
| Lai, YC | 1 |
| Tsai, IJ | 1 |
| Tsau, YK | 1 |
| Kajita, M | 1 |
| Niwa, T | 1 |
| Watanabe, K | 1 |
| Sanjurjo, P | 1 |
| Ruiz, JI | 1 |
| Montejo, M | 1 |
| Haan, EA | 1 |
| Danks, DM | 1 |
| Hoogenraad, NJ | 1 |
| Rogers, JG | 1 |
| Rosenberg, LE | 1 |
| Hyman, SL | 1 |
| Porter, CA | 1 |
| Page, TJ | 1 |
| Iwata, BA | 1 |
| Kissel, R | 1 |
| Batshaw, ML | 1 |
| Wolff, JA | 1 |
| Kelts, DG | 1 |
| Algert, S | 1 |
| Prodanos, C | 1 |
| Nyhan, WL | 1 |
1 review available for methylmalonic acid and Deficiency Disease, Ornithine Carbamoyltransferase
| Article | Year |
|---|---|
Treating genetic diseases: lessons from three children.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Child; Genetic Diseases, Inborn; Genetic Therapy; Hum | 1990 |
8 other studies available for methylmalonic acid and Deficiency Disease, Ornithine Carbamoyltransferase
| Article | Year |
|---|---|
Clinical onset and prognosis of Asian children with organic acidemias, as detected by analysis of urinary organic acids using GC/MS, instead of mass screening.
Topics: Adolescent; Age of Onset; Asia; Carboxylic Acids; Child; Child, Preschool; Disease Progression; Drug | 2005 |
Viral infections and prolonged fever after liver transplantation in young children with inborn errors of metabolism.
Topics: Carbamoyl-Phosphate Synthase I Deficiency Disease; Child, Preschool; Cytomegalovirus Infections; Eps | 2005 |
High-volume continuous venovenous hemofiltration as an effective therapy for acute management of inborn errors of metabolism in young children.
Topics: Carbamoyl-Phosphate Synthase I Deficiency Disease; Child; Child, Preschool; Female; Hemofiltration; | 2007 |
Analysis of urinary organic acids by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
Topics: Acids; Adolescent; Adult; Atmospheric Pressure; Benzoates; Child; Chromatography, Liquid; Female; Hu | 1993 |
Inborn errors of metabolism with a protein-restricted diet: effect on polyunsaturated fatty acids.
Topics: alpha-Linolenic Acid; Amino Acid Metabolism, Inborn Errors; Arachidonic Acid; Child; Child, Preschoo | 1997 |
Hereditary hyperammonaemic syndromes--a six year experience.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Ammonia; Child; Child, Preschool; Female; Humans; Infan | 1979 |
Behavior management of feeding disturbances in urea cycle and organic acid disorders.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Anorexia; Argininosuccinic Acid; Behavior Therapy; Chil | 1987 |
Alanine decreases the protein requirements of infants with inborn errors of amino acid metabolism.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Body Weight; Dietary Proteins; Female; H | 1985 |