methylmalonic acid has been researched along with Day Blindness in 3 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A previously healthy 7-week-old boy developed bilateral central retinal artery occlusions in the presence of hyperhomocysteinemia and elevated serum methylmalonic acid and was found to have a transcobalamin receptor mutation." | 3.78 | Bilateral central retinal artery occlusions in an infant with hyperhomocysteinemia. ( Costakos, D; Karth, P; Kim, J; Singh, R, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zwart, SR | 1 |
| Gibson, CR | 1 |
| Mader, TH | 1 |
| Ericson, K | 1 |
| Ploutz-Snyder, R | 1 |
| Heer, M | 1 |
| Smith, SM | 1 |
| Karth, P | 1 |
| Singh, R | 1 |
| Kim, J | 1 |
| Costakos, D | 1 |
| Pott, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Astronaut Vision Issues and One Carbon Metabolism: Expanded Polymorphism Evaluation and Evaluation in a Potential Analog Population[NCT02896452] | 60 participants (Actual) | Observational | 2016-10-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for methylmalonic acid and Day Blindness
| Article | Year |
|---|---|
Vision changes after spaceflight are related to alterations in folate- and vitamin B-12-dependent one-carbon metabolism.
Topics: Adult; Astronauts; Carbon Dioxide; Citrates; Cystathionine; Female; Folic Acid; Homocysteine; Humans | 2012 |
Bilateral central retinal artery occlusions in an infant with hyperhomocysteinemia.
Topics: Humans; Hydroxocobalamin; Hyperhomocysteinemia; Infant; Injections, Intramuscular; Male; Methylmalon | 2012 |
Detection of vitamin B12 deficiency in alcohol abuse.
Topics: Alcohol Abstinence; Alcoholism; Homocysteine; Humans; Methylmalonic Acid; Optic Atrophy, Hereditary, | 2014 |