methylmalonic acid has been researched along with Crohn Disease in 4 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 66 Crohn's disease (CD) and 30 ulcerative colitis (UC) patients were recruited." | 1.46 | Vitamin B12 deficiency in inflammatory bowel disease: a prospective observational pilot study. ( Afif, W; Battat, R; Bessissow, T; Bitton, A; Byer, J; Dionne, S; Kopylov, U; Nedjar, H; Rahme, E; Seidman, E; Sewitch, MJ; Waters, PJ; Zelikovic, E, 2017) |
| "Vitamin B12 deficiency is common in patients with CD." | 1.42 | Prevalence and Risk Factors for Functional Vitamin B12 Deficiency in Patients with Crohn's Disease. ( Anderson, SH; Griffin, N; Harrington, DJ; Irving, PM; Kariyawasam, VC; Mogan, SB; Pantelidou, M; Patel, KV; Porté, F; Sanderson, JD; Sobczyńska-Malefora, A; Ward, MG, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Battat, R | 1 |
| Kopylov, U | 1 |
| Byer, J | 1 |
| Sewitch, MJ | 1 |
| Rahme, E | 1 |
| Nedjar, H | 1 |
| Zelikovic, E | 1 |
| Dionne, S | 1 |
| Bessissow, T | 1 |
| Afif, W | 1 |
| Waters, PJ | 1 |
| Seidman, E | 1 |
| Bitton, A | 1 |
| Ward, MG | 1 |
| Kariyawasam, VC | 1 |
| Mogan, SB | 1 |
| Patel, KV | 1 |
| Pantelidou, M | 1 |
| Sobczyńska-Malefora, A | 1 |
| Porté, F | 1 |
| Griffin, N | 1 |
| Anderson, SH | 1 |
| Sanderson, JD | 1 |
| Harrington, DJ | 1 |
| Irving, PM | 1 |
| WHITE, AM | 1 |
| COX, EV | 1 |
| Lambert, D | 1 |
| Benhayoun, S | 1 |
| Adjalla, C | 1 |
| Gelot, MA | 1 |
| Renkes, P | 1 |
| Felden, F | 1 |
| Gerard, P | 1 |
| Belleville, F | 1 |
| Gaucher, P | 1 |
| Guéant, JL | 1 |
| Nicolas, JP | 1 |
4 other studies available for methylmalonic acid and Crohn Disease
| Article | Year |
|---|---|
Vitamin B12 deficiency in inflammatory bowel disease: a prospective observational pilot study.
Topics: Codon, Nonsense; Colitis, Ulcerative; Crohn Disease; Female; Fucosyltransferases; Galactoside 2-alph | 2017 |
Prevalence and Risk Factors for Functional Vitamin B12 Deficiency in Patients with Crohn's Disease.
Topics: Adult; Biomarkers; Colitis, Ulcerative; Crohn Disease; Female; Humans; Ileum; Male; Methylmalonic Ac | 2015 |
METHYLMALONIC ACID EXCRETION AND VITAMIN B12 DEFICIENCY IN THE HUMAN.
Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Carcinoma; Celiac Disease; Chromatography; Crohn Dis | 1964 |
Crohn's disease and vitamin B12 metabolism.
Topics: Adult; Crohn Disease; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Male; Methylmalonic Ac | 1996 |