methylmalonic acid has been researched along with Coronary Heart Disease in 5 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Elevated plasma methylmalonic acid (MMA) is reported in patients with established coronary heart disease (CHD) and is considered a marker of vitamin B12 deficiency." | 8.31 | Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2-cohort study. ( Berge, RK; Bjørnestad, EØ; Borsholm, R; Bønaa, KH; Dhar, I; Laupsa-Borge, J; Lysne, V; Mellgren, G; Nygård, OK; Olsen, T; Pedersen, ER; Svingen, GFT; Tell, GS; Ueland, PM; Ulvik, A, 2023) |
| "Hyperhomocysteinemia is an accepted risk factor for coronary artery disease, but the determining factors are not fully understood." | 7.72 | Hyperhomocysteinemia and vitamin B-12 deficiency are more striking in Syrians than in Germans--causes and implications. ( Herrmann, W; Jouma, M; Obeid, R, 2003) |
| "Elevated plasma methylmalonic acid (MMA) is reported in patients with established coronary heart disease (CHD) and is considered a marker of vitamin B12 deficiency." | 4.31 | Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2-cohort study. ( Berge, RK; Bjørnestad, EØ; Borsholm, R; Bønaa, KH; Dhar, I; Laupsa-Borge, J; Lysne, V; Mellgren, G; Nygård, OK; Olsen, T; Pedersen, ER; Svingen, GFT; Tell, GS; Ueland, PM; Ulvik, A, 2023) |
| "Hyperhomocysteinemia is an accepted risk factor for coronary artery disease, but the determining factors are not fully understood." | 3.72 | Hyperhomocysteinemia and vitamin B-12 deficiency are more striking in Syrians than in Germans--causes and implications. ( Herrmann, W; Jouma, M; Obeid, R, 2003) |
| " This study was undertaken to assess whether high serum levels of total homocysteine (tHcy) with its metabolites methylmalonic acid (MMA), methylcitric acid (MCA) and cystathionine (CYSTA) as well as elevated serum concentrations of the AGEs pentosidine and Nepsilon-carboxymethyllysine (CML) are independent risk factors for CVD, left ventricular hypertrophy (LVH) or hypertension as well as kidney dysfunction in renal transplant recipients (RTR)." | 3.72 | Serum levels of total homocysteine, homocysteine metabolites and of advanced glycation end-products (AGEs) in patients after renal transplantation. ( Busch, M; Franke, S; Kientsch-Engel, R; Müller, A; Sommer, M; Stein, G, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhar, I | 1 |
| Lysne, V | 1 |
| Ulvik, A | 1 |
| Svingen, GFT | 1 |
| Pedersen, ER | 1 |
| Bjørnestad, EØ | 1 |
| Olsen, T | 1 |
| Borsholm, R | 1 |
| Laupsa-Borge, J | 1 |
| Ueland, PM | 1 |
| Tell, GS | 1 |
| Berge, RK | 1 |
| Mellgren, G | 1 |
| Bønaa, KH | 1 |
| Nygård, OK | 1 |
| Herrmann, W | 1 |
| Obeid, R | 1 |
| Jouma, M | 1 |
| Franke, S | 1 |
| Müller, A | 1 |
| Sommer, M | 1 |
| Busch, M | 1 |
| Kientsch-Engel, R | 1 |
| Stein, G | 1 |
| Glueck, CJ | 1 |
| Shaw, P | 1 |
| Lang, JE | 1 |
| Tracy, T | 1 |
| Sieve-Smith, L | 1 |
| Wang, Y | 1 |
| Carlsen, SM | 1 |
| Følling, I | 1 |
| Grill, V | 1 |
| Bjerve, KS | 1 |
| Schneede, J | 1 |
| Refsum, H | 1 |
1 trial available for methylmalonic acid and Coronary Heart Disease
| Article | Year |
|---|---|
Metformin increases total serum homocysteine levels in non-diabetic male patients with coronary heart disease.
Topics: Adult; Coronary Disease; Cysteine; Folic Acid; Homocysteine; Humans; Hypoglycemic Agents; Male; Metf | 1997 |
4 other studies available for methylmalonic acid and Coronary Heart Disease
| Article | Year |
|---|---|
Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2-cohort study.
Topics: Aged; Biomarkers; Cohort Studies; Coronary Disease; Female; Humans; Methylmalonic Acid; Myocardial I | 2023 |
Hyperhomocysteinemia and vitamin B-12 deficiency are more striking in Syrians than in Germans--causes and implications.
Topics: Adult; Arabs; Cholesterol, LDL; Coronary Disease; Female; Germany; Homocysteine; Humans; Hyperhomocy | 2003 |
Serum levels of total homocysteine, homocysteine metabolites and of advanced glycation end-products (AGEs) in patients after renal transplantation.
Topics: Adult; Arginine; Coronary Disease; Cystathionine; Female; Glycation End Products, Advanced; Homocyst | 2003 |
Evidence that homocysteine is an independent risk factor for atherosclerosis in hyperlipidemic patients.
Topics: Aged; Analysis of Variance; Arteriosclerosis; Coronary Disease; Cystathionine; Folic Acid; Homocyste | 1995 |