methylmalonic acid has been researched along with Complications, Pregnancy in 23 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report on a favourable pregnancy in a woman affected by mut- methylmalonic acidaemia." | 7.71 | Successful pregnancy in a woman with mut- methylmalonic acidaemia. ( Baiocco, F; Boenzi, S; Deodato, F; Dionisi-Vici, C; Rizzo, C; Sabetta, G, 2002) |
| "Methylmalonic acidaemia is an inborn error of metabolism characterized by recurrent episodes of life-threatening ketoacidosis." | 7.70 | Successful pregnancy in severe methylmalonic acidaemia. ( Desnick, RJ; Eddleman, K; Gaddipati, S; Sansaricq, C; Snyderman, SE; Wasserstein, MP, 1999) |
| "Presently pregnancy is no more exceptional in women with metabolic diseases." | 5.39 | Pregnancy in a methylmalonic acidemia patient with kidney transplantation: a case report. ( Bellelli, E; Carducci, C; Elli, M; Gentile, I; Labriola, D; Lubrano, R; Paoli, S; Pérez, B; Santagata, S; Ugarte, M, 2013) |
| "Methylmalonic aciduria is a rare metabolic disorder of amino acid metabolism that is characterized by accumulation of large amounts of methylmalonic acid in the blood and urine." | 5.29 | Methylmalonic aciduria in pregnancy: a case report. ( Diss, E; Iams, J; Reed, N; Roe, C; Roe, DS, 1995) |
| "We report on a favourable pregnancy in a woman affected by mut- methylmalonic acidaemia." | 3.71 | Successful pregnancy in a woman with mut- methylmalonic acidaemia. ( Baiocco, F; Boenzi, S; Deodato, F; Dionisi-Vici, C; Rizzo, C; Sabetta, G, 2002) |
| "Methylmalonic acidaemia is an inborn error of metabolism characterized by recurrent episodes of life-threatening ketoacidosis." | 3.70 | Successful pregnancy in severe methylmalonic acidaemia. ( Desnick, RJ; Eddleman, K; Gaddipati, S; Sansaricq, C; Snyderman, SE; Wasserstein, MP, 1999) |
| "To determine the significance of the commonly observed fall in serum vitamin B12 levels during pregnancy, serum levels of the B12 metabolites methylmalonic acid (MMA) and homocysteine (Hcy) were measured in a group of 50 pregnant patients with subnormal serum B12 (range 45-199 pg/ml) and the results compared with those of 25 pregnant controls (serum B12(208-580) pg/ml)." | 3.69 | Biochemical indices of vitamin B12 nutrition in pregnant patients with subnormal serum vitamin B12 levels. ( Bennett, M; Bottiglieri, T; Hyland, K; McGrath, K; Metz, J, 1995) |
| "Methylmalonic acid (MMA) is a sensitive indicator of B12 status." | 1.46 | South Asian Ethnicity Is Related to the Highest Risk of Vitamin B12 Deficiency in Pregnant Canadian Women. ( Green, TJ; Isman, C; Jeruszka-Bielak, M; Lamers, Y; Li, W; Schroder, TH, 2017) |
| "Presently pregnancy is no more exceptional in women with metabolic diseases." | 1.39 | Pregnancy in a methylmalonic acidemia patient with kidney transplantation: a case report. ( Bellelli, E; Carducci, C; Elli, M; Gentile, I; Labriola, D; Lubrano, R; Paoli, S; Pérez, B; Santagata, S; Ugarte, M, 2013) |
| "Methylmalonic aciduria is a rare metabolic disorder of amino acid metabolism that is characterized by accumulation of large amounts of methylmalonic acid in the blood and urine." | 1.29 | Methylmalonic aciduria in pregnancy: a case report. ( Diss, E; Iams, J; Reed, N; Roe, C; Roe, DS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 10 (43.48) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jeruszka-Bielak, M | 1 |
| Isman, C | 1 |
| Schroder, TH | 2 |
| Li, W | 1 |
| Green, TJ | 1 |
| Lamers, Y | 2 |
| Lubrano, R | 1 |
| Bellelli, E | 1 |
| Gentile, I | 1 |
| Paoli, S | 1 |
| Carducci, C | 2 |
| Santagata, S | 1 |
| Pérez, B | 1 |
| Ugarte, M | 1 |
| Labriola, D | 1 |
| Elli, M | 1 |
| Scolamiero, E | 1 |
| Villani, GR | 1 |
| Ingenito, L | 1 |
| Pecce, R | 1 |
| Albano, L | 1 |
| Caterino, M | 1 |
| di Girolamo, MG | 1 |
| Di Stefano, C | 1 |
| Franzese, I | 1 |
| Gallo, G | 1 |
| Ruoppolo, M | 1 |
| Kalay, Z | 1 |
| Islek, A | 1 |
| Parlak, M | 1 |
| Kirecci, A | 1 |
| Guney, O | 1 |
| Koklu, E | 1 |
| Kalay, S | 1 |
| Visentin, CE | 1 |
| Masih, SP | 1 |
| Plumptre, L | 1 |
| Sohn, KJ | 1 |
| Ly, A | 1 |
| Lausman, AY | 1 |
| Berger, H | 1 |
| Croxford, R | 1 |
| Kim, YI | 1 |
| O'Connor, DL | 1 |
| Vanderjagt, DJ | 1 |
| Ujah, IA | 1 |
| Patel, A | 1 |
| Kellywood, J | 1 |
| Crossey, MJ | 1 |
| Allen, RH | 1 |
| Stabler, SP | 1 |
| Obande, OS | 1 |
| Glew, RH | 1 |
| Boneh, A | 1 |
| Greaves, RF | 1 |
| Garra, G | 1 |
| Pitt, JJ | 1 |
| Deodato, F | 1 |
| Rizzo, C | 1 |
| Boenzi, S | 1 |
| Baiocco, F | 1 |
| Sabetta, G | 1 |
| Dionisi-Vici, C | 1 |
| WHITE, AM | 1 |
| COX, EV | 1 |
| Adeyemi, OA | 1 |
| Girish, T | 1 |
| Mukhopadhyay, S | 1 |
| Olczak, SA | 1 |
| Ahmed, Z | 1 |
| Campbell, CD | 1 |
| Ganesh, J | 1 |
| Ficicioglu, C | 1 |
| Milman, N | 1 |
| Byg, KE | 1 |
| Bergholt, T | 1 |
| Eriksen, L | 1 |
| Hvas, AM | 1 |
| Yajnik, CS | 1 |
| Deshpande, SS | 1 |
| Jackson, AA | 1 |
| Refsum, H | 1 |
| Rao, S | 1 |
| Fisher, DJ | 1 |
| Bhat, DS | 1 |
| Naik, SS | 1 |
| Coyaji, KJ | 1 |
| Joglekar, CV | 1 |
| Joshi, N | 1 |
| Lubree, HG | 1 |
| Deshpande, VU | 1 |
| Rege, SS | 1 |
| Fall, CH | 1 |
| Song, YZ | 1 |
| Li, BX | 1 |
| Hao, H | 1 |
| Xin, RL | 1 |
| Zhang, T | 1 |
| Zhang, CH | 1 |
| Kobayashi, K | 1 |
| Wang, ZN | 1 |
| Zheng, XY | 1 |
| Metz, J | 1 |
| McGrath, K | 1 |
| Bennett, M | 1 |
| Hyland, K | 1 |
| Bottiglieri, T | 1 |
| Diss, E | 1 |
| Iams, J | 1 |
| Reed, N | 1 |
| Roe, DS | 1 |
| Roe, C | 1 |
| Norberg, B | 1 |
| Wasserstein, MP | 1 |
| Gaddipati, S | 1 |
| Snyderman, SE | 1 |
| Eddleman, K | 1 |
| Desnick, RJ | 1 |
| Sansaricq, C | 1 |
| Pardo, J | 1 |
| Peled, Y | 1 |
| Bar, J | 1 |
| Hod, M | 1 |
| Sela, BA | 1 |
| Rafael, ZB | 1 |
| Orvieto, R | 1 |
| McMullin, MF | 1 |
| Young, PB | 1 |
| Bailie, KE | 1 |
| Savage, GA | 1 |
| Lappin, TR | 1 |
| White, R | 1 |
| Petersen, BJ | 1 |
| Vahouny, GV | 1 |
| Fisher, GE | 1 |
| van der Meer, SB | 1 |
| Spaapen, LJ | 1 |
| Fowler, B | 1 |
| Jakobs, C | 1 |
| Kleijer, WJ | 1 |
| Wendel, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT02244684] | 368 participants (Actual) | Observational | 2010-09-30 | Completed | |||
| Supplementation of Vitamin B12 in Pregnancy and Postpartum on Growth and Cognitive Functioning in Early Childhood: A Randomized, Placebo Controlled Trial[NCT03071666] | Phase 2/Phase 3 | 800 participants (Actual) | Interventional | 2017-03-27 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
23 other studies available for methylmalonic acid and Complications, Pregnancy
| Article | Year |
|---|---|
South Asian Ethnicity Is Related to the Highest Risk of Vitamin B12 Deficiency in Pregnant Canadian Women.
Topics: Adolescent; Adult; Asia; Biomarkers; Canada; Ethnicity; Female; Gestational Age; Humans; India; Meth | 2017 |
Pregnancy in a methylmalonic acidemia patient with kidney transplantation: a case report.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amniotic Fluid; Female; Follow-Up Studies; Glomerular F | 2013 |
Maternal vitamin B12 deficiency detected in expanded newborn screening.
Topics: Carnitine; Female; Folic Acid; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid; Neonatal S | 2014 |
Reliable and powerful laboratory markers of cobalamin deficiency in the newborn: plasma and urinary methylmalonic acid.
Topics: Adult; Biomarkers; Cohort Studies; Female; Homocysteine; Humans; Infant, Newborn; Methylmalonic Acid | 2016 |
Low Serum Vitamin B-12 Concentrations Are Prevalent in a Cohort of Pregnant Canadian Women.
Topics: Adult; Canada; Diet; Dietary Supplements; DNA Methylation; Female; Fetal Blood; Fetus; Folic Acid; H | 2016 |
Subclinical vitamin B12 deficiency in pregnant women attending an antenatal clinic in Nigeria.
Topics: Adult; Ambulatory Care Facilities; Female; Folic Acid; Hemoglobins; Homocysteine; Humans; Methylmalo | 2009 |
Metabolic treatment of pregnancy and postdelivery period in a patient with cobalamin A disease.
Topics: Cobamides; Female; Humans; Hydroxocobalamin; Metabolism, Inborn Errors; Methylmalonic Acid; Pregnanc | 2002 |
Successful pregnancy in a woman with mut- methylmalonic acidaemia.
Topics: Adult; Carnitine; Female; Humans; Metabolism, Inborn Errors; Methylmalonic Acid; Pregnancy; Pregnanc | 2002 |
METHYLMALONIC ACID EXCRETION AND VITAMIN B12 DEFICIENCY IN THE HUMAN.
Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Carcinoma; Celiac Disease; Chromatography; Crohn Dis | 1964 |
Methylmalonic acidaemia: a rare metabolic disorder in pregnancy.
Topics: Adult; Cesarean Section; Female; Humans; Infant, Newborn; Infant, Premature; Metabolism, Inborn Erro | 2004 |
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; | 2005 |
Cobalamin status during normal pregnancy and postpartum: a longitudinal study comprising 406 Danish women.
Topics: Adult; Cohort Studies; Denmark; Female; Follow-Up Studies; Hemoglobins; Homocysteine; Humans; Infant | 2006 |
Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study.
Topics: Adipose Tissue; Anthropometry; Body Composition; Body Mass Index; Child; Female; Folic Acid; Homocys | 2008 |
Selective screening for inborn errors of metabolism and secondary methylmalonic aciduria in pregnancy at high risk district of neural tube defects: a human metabolome study by GC-MS in China.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; China; Female; Gas | 2008 |
Biochemical indices of vitamin B12 nutrition in pregnant patients with subnormal serum vitamin B12 levels.
Topics: Female; Homocysteine; Humans; Methylmalonic Acid; Nutritional Status; Pregnancy; Pregnancy Complicat | 1995 |
Methylmalonic aciduria in pregnancy: a case report.
Topics: Adult; Female; Humans; Infant, Newborn; Metabolism, Inborn Errors; Methylmalonic Acid; Pregnancy; Pr | 1995 |
Turn of tide for oral vitamin B12 treatment.
Topics: Administration, Oral; Aged; Biological Availability; Biomarkers; England; Female; Homocysteine; Huma | 1999 |
Successful pregnancy in severe methylmalonic acidaemia.
Topics: Acidosis; Adult; Female; Humans; Hydroxocobalamin; Infant, Newborn; Male; Metabolism, Inborn Errors; | 1999 |
Evaluation of low serum vitamin B(12) in the non-anaemic pregnant patient.
Topics: Adult; Erythrocyte Indices; Female; Gestational Age; Homocysteine; Humans; Methylmalonic Acid; Parit | 2000 |
Homocysteine and methylmalonic acid as indicators of folate and vitamin B12 deficiency in pregnancy.
Topics: Adult; Biomarkers; Female; Folic Acid Deficiency; Homocysteine; Humans; Methylmalonic Acid; Pregnanc | 2001 |
Cardiac structure and function in vitamin B-12-deprived rats.
Topics: Animals; Fatty Acids; Female; Maternal-Fetal Exchange; Methylmalonic Acid; Mitochondria, Muscle; Myo | 1975 |
Effect of cobalt deficiency in the pregnant ewe on reproductive performance and lamb viability.
Topics: Animals; Body Weight; Cobalt; Colostrum; Female; Fetal Death; Immunoglobulin G; Methylmalonic Acid; | 1991 |
Prenatal treatment of a patient with vitamin B12-responsive methylmalonic acidemia.
Topics: Acidosis; Administration, Oral; Female; Humans; Metabolism, Inborn Errors; Methylmalonic Acid; Pregn | 1990 |