methylmalonic acid has been researched along with Central Nervous System Disease in 3 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The full syndrome of a vitamin B12 deficiency is rather simple to diagnose." | 6.39 | [Low serum vitamin B 12 level and vitamin B 12 deficiency in the elderly. When should supplement be provided?]. ( de Rooij, S; Hooijer, C; Thijssen, C; van Bruggen, R, 1994) |
| "The full syndrome of a vitamin B12 deficiency is rather simple to diagnose." | 2.39 | [Low serum vitamin B 12 level and vitamin B 12 deficiency in the elderly. When should supplement be provided?]. ( de Rooij, S; Hooijer, C; Thijssen, C; van Bruggen, R, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Rooij, S | 1 |
| van Bruggen, R | 1 |
| Thijssen, C | 1 |
| Hooijer, C | 1 |
| Allen, RH | 1 |
| Stabler, SP | 1 |
| Lindenbaum, J | 1 |
| Roodhooft, AM | 1 |
| Baumgartner, ER | 1 |
| Martin, JJ | 1 |
| Blom, W | 1 |
| Van Acker, KJ | 1 |
3 reviews available for methylmalonic acid and Central Nervous System Disease
| Article | Year |
|---|---|
[Low serum vitamin B 12 level and vitamin B 12 deficiency in the elderly. When should supplement be provided?].
Topics: Aged; Anemia, Pernicious; Central Nervous System Diseases; Deoxyuridine; Humans; Methylmalonic Acid; | 1994 |
Relevance of vitamins, homocysteine and other metabolites in neuropsychiatric disorders.
Topics: Central Nervous System Diseases; Citrates; Demyelinating Diseases; Folic Acid; Homocysteine; Humans; | 1998 |
Symmetrical necrosis of the basal ganglia in methylmalonic acidaemia.
Topics: Acidosis; Central Nervous System Diseases; Child; Child, Preschool; Combined Modality Therapy; Fibro | 1990 |