methylmalonic acid has been researched along with Brain Damage, Chronic in 1 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have identified a patient with methylmalonic aciduria and homocystinuria due to a defect in cobalamin metabolism of the cb1C type mutant." | 7.67 | A cobalamin metabolic defect with homocystinuria, methylmalonic aciduria and macrocytic anemia. ( Isenberg, JN; Mamlok, RJ; Norcross, K; Rassin, DK; Tallan, HH, 1986) |
| "We have identified a patient with methylmalonic aciduria and homocystinuria due to a defect in cobalamin metabolism of the cb1C type mutant." | 3.67 | A cobalamin metabolic defect with homocystinuria, methylmalonic aciduria and macrocytic anemia. ( Isenberg, JN; Mamlok, RJ; Norcross, K; Rassin, DK; Tallan, HH, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mamlok, RJ | 1 |
| Isenberg, JN | 1 |
| Rassin, DK | 1 |
| Norcross, K | 1 |
| Tallan, HH | 1 |
1 other study available for methylmalonic acid and Brain Damage, Chronic
| Article | Year |
|---|---|
A cobalamin metabolic defect with homocystinuria, methylmalonic aciduria and macrocytic anemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Metabolism, Inborn Errors; Ane | 1986 |