methylmalonic acid has been researched along with Benign Neoplasms in 13 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since both cancer and neurotoxic antineoplastic agents increase oxidative stress, a role for functional B12 deficiency in CIPN was considered." | 1.43 | Functional vitamin B12 deficiency in advanced malignancy: implications for the management of neuropathy and neuropathic pain. ( Solomon, LR, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Gomes, AP | 2 |
| Ilter, D | 2 |
| Low, V | 3 |
| Drapela, S | 1 |
| Schild, T | 3 |
| Mullarky, E | 2 |
| Han, J | 2 |
| Elia, I | 2 |
| Broekaert, D | 2 |
| Rosenzweig, A | 2 |
| Nagiec, M | 1 |
| Nunes, JB | 1 |
| Schaffer, BE | 1 |
| Mutvei, AP | 2 |
| Asara, JM | 1 |
| Cantley, LC | 3 |
| Fendt, SM | 2 |
| Blenis, J | 3 |
| Kay, EJ | 1 |
| Zanivan, S | 1 |
| Li, Z | 1 |
| Luga, V | 1 |
| Sun, J | 1 |
| Earlie, E | 1 |
| Parang, B | 1 |
| Shobana Ganesh, K | 1 |
| Cho, S | 1 |
| Endress, J | 1 |
| Hu, M | 1 |
| Lyden, D | 1 |
| Jin, W | 1 |
| Guo, C | 1 |
| Dephoure, N | 2 |
| Laughney, AM | 1 |
| Endress, JE | 1 |
| Fernández-García, J | 1 |
| Ahmed, A | 1 |
| Planque, M | 1 |
| Kinzig, C | 1 |
| Asara, J | 1 |
| de Cabo, R | 1 |
| Wang, H | 1 |
| Zhang, XH | 1 |
| Oussalah, A | 1 |
| Levy, J | 1 |
| Filhine-Trésarrieu, P | 1 |
| Namour, F | 1 |
| Guéant, JL | 1 |
| Dizdarevic, S | 1 |
| McCready, R | 1 |
| Turner, JF | 1 |
| Bagley, MC | 1 |
| Blower, P | 1 |
| Schmid, P | 1 |
| Flux, G | 1 |
| Hall, A | 1 |
| Ziv, I | 2 |
| Vashi, P | 1 |
| Edwin, P | 1 |
| Popiel, B | 1 |
| Lammersfeld, C | 1 |
| Gupta, D | 1 |
| Solomon, LR | 1 |
| Grimberg, H | 1 |
| Levin, G | 1 |
| Shirvan, A | 1 |
| Cohen, A | 1 |
| Yogev-Falach, M | 1 |
| Reshef, A | 1 |
| Arendt, JF | 1 |
| Nexo, E | 1 |
| Niyikiza, C | 1 |
| Hanauske, AR | 1 |
| Rusthoven, JJ | 1 |
| Calvert, AH | 1 |
| Allen, R | 1 |
| Paoletti, P | 1 |
| Bunn, PA | 1 |
| Azzoli, CG | 1 |
| Krug, LM | 1 |
| Gomez, J | 1 |
| Miller, VA | 1 |
| Kris, MG | 1 |
| Ginsberg, MS | 1 |
| Henry, R | 1 |
| Jones, J | 1 |
| Tyson, L | 1 |
| Dunne, M | 1 |
| Pizzo, B | 1 |
| Farmer, A | 1 |
| Venkatraman, E | 1 |
| Steffen, R | 1 |
| Sirotnak, FM | 1 |
2 reviews available for methylmalonic acid and Benign Neoplasms
| Article | Year |
|---|---|
Association of
Topics: Adult; Aged; Alleles; Alzheimer Disease; Carbon; Child; Congenital Abnormalities; Female; Genotype; | 2017 |
Pemetrexed safety and dosing strategy.
Topics: Antimetabolites, Antineoplastic; Clinical Trials as Topic; Folic Acid; Folic Acid Antagonists; Gluta | 2002 |
1 trial available for methylmalonic acid and Benign Neoplasms
| Article | Year |
|---|---|
A phase 1 study of pralatrexate in combination with paclitaxel or docetaxel in patients with advanced solid tumors.
Topics: Adult; Aged; Aminopterin; Antineoplastic Combined Chemotherapy Protocols; Dietary Supplements; Docet | 2007 |
10 other studies available for methylmalonic acid and Benign Neoplasms
| Article | Year |
|---|---|
Altered propionate metabolism contributes to tumour progression and aggressiveness.
Topics: Humans; Methylmalonic Acid; Neoplasms; Phenotype; Propionates; Signal Transduction | 2022 |
Methylmalonic acid: an age-related metabolite that drives tumour aggressiveness.
Topics: Humans; Methylmalonic Acid; Neoplasms | 2022 |
Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.
Topics: Cancer-Associated Fibroblasts; Extracellular Vesicles; Humans; Interleukin-6; Methylmalonic Acid; Ne | 2022 |
Age-induced accumulation of methylmalonic acid promotes tumour progression.
Topics: Adult; Aged; Aging; Animals; Cell Line, Tumor; Disease Progression; Female; Gene Expression Regulati | 2020 |
Molecules in the blood of older people promote cancer spread.
Topics: Aged; Aged, 80 and over; Aging; Humans; Methylmalonic Acid; Neoplasms | 2020 |
Radiolabelled apoptotic probe may be a vehicle for a novel multimodality radionuclide tumour therapy.
Topics: Apoptosis; Humans; Methylmalonic Acid; Neoplasms; Radiopharmaceuticals | 2014 |
Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cross-Sectional Studies; Female; Homocysteine; Humans; M | 2016 |
Functional vitamin B12 deficiency in advanced malignancy: implications for the management of neuropathy and neuropathic pain.
Topics: Aged; Female; Humans; Male; Methylmalonic Acid; Middle Aged; Neoplasms; Neuralgia; Peripheral Nervou | 2016 |
Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkyla | 2009 |
Cobalamin related parameters and disease patterns in patients with increased serum cobalamin levels.
Topics: Aged; Alcoholism; Antigens, CD; Female; Humans; Liver Diseases; Male; Methylmalonic Acid; Middle Age | 2012 |