methylmalonic acid has been researched along with Anemia in 14 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We attempted to attribute associations that we previously found between higher folate status and anemia and cognitive test performance to circulating unmetabolized folic acid or 5-methyltetrahydrofolate (5MeTHF)." | 7.76 | Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. ( Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J, 2010) |
| "Subtle cobalamin deficiency states, where low serum cobalamin levels are not accompanied by megaloblastic anemia or malabsorption of free cobalamin, often display metabolic evidence of cellular depletion as shown by the deoxyuridine suppression test." | 7.68 | Reversal by cobalamin therapy of minimal defects in the deoxyuridine suppression test in patients without anemia: further evidence for a subtle metabolic cobalamin deficiency. ( Carmel, R, 1992) |
| "We attempted to attribute associations that we previously found between higher folate status and anemia and cognitive test performance to circulating unmetabolized folic acid or 5-methyltetrahydrofolate (5MeTHF)." | 3.76 | Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. ( Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J, 2010) |
| " We report here on a case of anemia associated with erythroblastopenia-that is less frequent in this context-in a neonate with methylmalonic aciduria." | 3.69 | Erythroblastopenia associated with methylmalonic aciduria. Case report and in vitro studies. ( Blum, D; Clercx, A; Corazza, F; Fondu, P; Mardens, Y, 1996) |
| "Subtle cobalamin deficiency states, where low serum cobalamin levels are not accompanied by megaloblastic anemia or malabsorption of free cobalamin, often display metabolic evidence of cellular depletion as shown by the deoxyuridine suppression test." | 3.68 | Reversal by cobalamin therapy of minimal defects in the deoxyuridine suppression test in patients without anemia: further evidence for a subtle metabolic cobalamin deficiency. ( Carmel, R, 1992) |
| " Characteristic features in such patients included paresthesia, sensory loss, ataxia, dementia, and psychiatric disorders; longstanding neurologic symptoms without anemia; normal white-cell and platelet counts and serum bilirubin and lactate dehydrogenase levels; and markedly elevated serum concentrations of methylmalonic acid and total homocysteine." | 3.67 | Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. ( Allen, RH; Brust, JC; Garrett, TJ; Healton, EB; Lindenbaum, J; Marcell, PD; Podell, ER; Savage, DG; Stabler, SP, 1988) |
| "Methylmalonic aciduria (MMA) is a common one of the congenital disorders of organic acids metabolism." | 2.73 | [Clinical studies on fifty-seven Chinese patients with combined methylmalonic aciduria and homocysteinemia]. ( Dong, JH; Jiang, YW; Liu, P; Qin, J; Song, JQ; Wang, LF; Wu, XR; Yan, R; Yang, YL; Zhang, Y; Zhang, YH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morris, MS | 1 |
| Jacques, PF | 1 |
| Rosenberg, IH | 1 |
| Selhub, J | 1 |
| Bross, MH | 1 |
| Soch, K | 1 |
| Smith-Knuppel, T | 1 |
| Haslam, A | 1 |
| Hausman, DB | 1 |
| Johnson, MA | 1 |
| Davey, A | 1 |
| Poon, LW | 1 |
| Allen, RH | 2 |
| Stabler, SP | 2 |
| Kwok, T | 1 |
| Cheng, G | 1 |
| Woo, J | 1 |
| Lai, WK | 1 |
| Pang, CP | 1 |
| Rogers, LM | 1 |
| Boy, E | 1 |
| Miller, JW | 1 |
| Green, R | 1 |
| Sabel, JC | 1 |
| Allen, LH | 1 |
| Segal, R | 1 |
| Baumoehl, Y | 1 |
| Elkayam, O | 1 |
| Levartovsky, D | 1 |
| Litinsky, I | 1 |
| Paran, D | 1 |
| Wigler, I | 1 |
| Habot, B | 1 |
| Leibovitz, A | 1 |
| Sela, BA | 1 |
| Caspi, D | 1 |
| COX, EV | 2 |
| WHITE, AM | 2 |
| Hvas, AM | 1 |
| Nexo, E | 1 |
| Zhang, Y | 1 |
| Song, JQ | 1 |
| Liu, P | 1 |
| Yan, R | 1 |
| Dong, JH | 1 |
| Yang, YL | 1 |
| Wang, LF | 1 |
| Jiang, YW | 1 |
| Zhang, YH | 1 |
| Qin, J | 1 |
| Wu, XR | 1 |
| Corazza, F | 1 |
| Blum, D | 1 |
| Clercx, A | 1 |
| Mardens, Y | 1 |
| Fondu, P | 1 |
| Carmel, R | 1 |
| Lindenbaum, J | 1 |
| Healton, EB | 1 |
| Savage, DG | 1 |
| Brust, JC | 1 |
| Garrett, TJ | 1 |
| Podell, ER | 1 |
| Marcell, PD | 1 |
| Ho, CH | 1 |
| Chang, HC | 1 |
| Yeh, SF | 1 |
2 trials available for methylmalonic acid and Anemia
| Article | Year |
|---|---|
Holotranscobalamin--a first choice assay for diagnosing early vitamin B deficiency?
Topics: Adult; Aged; Aged, 80 and over; Anemia; Biomarkers; Creatinine; Female; Homocysteine; Humans; Male; | 2005 |
[Clinical studies on fifty-seven Chinese patients with combined methylmalonic aciduria and homocysteinemia].
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Anemia; Carnitine; Child; Child, Preschool; | 2007 |
12 other studies available for methylmalonic acid and Anemia
| Article | Year |
|---|---|
Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors.
Topics: Aged; Aging; Anemia; Anemia, Macrocytic; Blood Cell Count; Cognition; Cognition Disorders; Cystatin | 2010 |
Anemia in older persons.
Topics: Aged; Algorithms; Anemia; Deficiency Diseases; Erythrocyte Indices; Female; Ferritins; Folic Acid; H | 2010 |
Prevalence and predictors of anemia in a population-based study of octogenarians and centenarians in Georgia.
Topics: Aged, 80 and over; Anemia; C-Reactive Protein; Chronic Disease; Creatinine; Dietary Supplements; Ery | 2012 |
Independent effect of vitamin B12 deficiency on hematological status in older Chinese vegetarian women.
Topics: Aged; Anemia; Blood Cell Count; Blood Proteins; China; Cross-Sectional Studies; Diet, Vegetarian; Er | 2002 |
High prevalence of cobalamin deficiency in Guatemalan schoolchildren: associations with low plasma holotranscobalamin II and elevated serum methylmalonic acid and plasma homocysteine concentrations.
Topics: Analysis of Variance; Anemia; Biomarkers; Child; Creatinine; Female; Folic Acid; Guatemala; Hematocr | 2003 |
Anemia, serum vitamin B12, and folic acid in patients with rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus.
Topics: Adult; Aged; Aged, 80 and over; Anemia; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cohort Studies; | 2004 |
Methylmalonic acid excretion: an index of vitamin-B12 deficiency.
Topics: Anemia; Anemia, Macrocytic; Humans; Malonates; Methylmalonic Acid; Vitamin B 12 Deficiency; Vitamins | 1962 |
METHYLMALONIC ACID EXCRETION AND VITAMIN B12 DEFICIENCY IN THE HUMAN.
Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Carcinoma; Celiac Disease; Chromatography; Crohn Dis | 1964 |
Erythroblastopenia associated with methylmalonic aciduria. Case report and in vitro studies.
Topics: Amino Acid Metabolism, Inborn Errors; Anemia; Blood; Cells, Cultured; Erythroblasts; Erythroid Precu | 1996 |
Reversal by cobalamin therapy of minimal defects in the deoxyuridine suppression test in patients without anemia: further evidence for a subtle metabolic cobalamin deficiency.
Topics: Aged; Aged, 80 and over; Anemia; Bone Marrow; Deoxyuridine; DNA; Female; Humans; Male; Methylmalonic | 1992 |
Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis.
Topics: Adolescent; Adult; Aged; Anemia; Anemia, Megaloblastic; Ataxia; Erythrocyte Indices; Erythrocytes; F | 1988 |
Quantitation of urinary methylmalonic acid by gas chromatography mass spectrometry and its clinical applications.
Topics: Aged; Anemia; Anemia, Megaloblastic; China; Humans; Malonates; Methylmalonic Acid; Middle Aged; Vita | 1987 |