methylmalonic acid has been researched along with Anemia, Macrocytic in 14 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Anemia, Macrocytic: Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We attempted to attribute associations that we previously found between higher folate status and anemia and cognitive test performance to circulating unmetabolized folic acid or 5-methyltetrahydrofolate (5MeTHF)." | 7.76 | Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. ( Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J, 2010) |
| "We have identified a patient with methylmalonic aciduria and homocystinuria due to a defect in cobalamin metabolism of the cb1C type mutant." | 7.67 | A cobalamin metabolic defect with homocystinuria, methylmalonic aciduria and macrocytic anemia. ( Isenberg, JN; Mamlok, RJ; Norcross, K; Rassin, DK; Tallan, HH, 1986) |
| "We attempted to attribute associations that we previously found between higher folate status and anemia and cognitive test performance to circulating unmetabolized folic acid or 5-methyltetrahydrofolate (5MeTHF)." | 3.76 | Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. ( Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J, 2010) |
| "We have identified a patient with methylmalonic aciduria and homocystinuria due to a defect in cobalamin metabolism of the cb1C type mutant." | 3.67 | A cobalamin metabolic defect with homocystinuria, methylmalonic aciduria and macrocytic anemia. ( Isenberg, JN; Mamlok, RJ; Norcross, K; Rassin, DK; Tallan, HH, 1986) |
| "Methylmalonic acid (MMA) level was used as an indicator of vitamin B12 status." | 1.37 | Parenteral vitamin B12 in macrocytic hemodialysis patients reduced MMA levels but did not change mean red cell volume or hemoglobin. ( Jastrzebski, J; Li, G; Martyn, A; Shalansky, K; Snyder, F; Su, VC; Yeung, CK; Zalunardo, N, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, R | 1 |
| Oh, Y | 1 |
| Park, MJ | 1 |
| Kim, S | 1 |
| Kim, Y | 1 |
| Lee, SG | 1 |
| Lee, EH | 1 |
| Morris, MS | 1 |
| Jacques, PF | 1 |
| Rosenberg, IH | 1 |
| Selhub, J | 1 |
| Su, VC | 1 |
| Shalansky, K | 1 |
| Jastrzebski, J | 1 |
| Martyn, A | 1 |
| Li, G | 1 |
| Yeung, CK | 1 |
| Snyder, F | 1 |
| Zalunardo, N | 1 |
| COX, EV | 2 |
| WHITE, AM | 2 |
| Erol, I | 1 |
| Alehan, F | 1 |
| Gümüs, A | 1 |
| Savage, DG | 1 |
| Ogundipe, A | 1 |
| Allen, RH | 1 |
| Stabler, SP | 1 |
| Lindenbaum, J | 1 |
| Carmel, R | 1 |
| Perri, GC | 1 |
| Gombe, S | 1 |
| Verjee, ZH | 1 |
| Kondo, H | 1 |
| Kakinuma, H | 1 |
| Kanazawa, S | 1 |
| Iseki, T | 1 |
| Goto, S | 1 |
| Ohto, M | 1 |
| Yonemitsu, H | 1 |
| Okuda, K | 1 |
| Yamauchi, H | 1 |
| Omine, M | 1 |
| Tsukamoto, N | 1 |
| Katahira, H | 1 |
| Karasawa, M | 1 |
| Sugita, Y | 1 |
| Yatabe, H | 1 |
| Iwata, N | 1 |
| Maekawa, T | 1 |
| Mamlok, RJ | 1 |
| Isenberg, JN | 1 |
| Rassin, DK | 1 |
| Norcross, K | 1 |
| Tallan, HH | 1 |
| Tuchman, M | 1 |
| Kelly, P | 1 |
| Watkins, D | 1 |
| Rosenblatt, DS | 1 |
1 review available for methylmalonic acid and Anemia, Macrocytic
| Article | Year |
|---|---|
The laboratory diagnosis of megaloblastic anemias.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Antibodies; Clinical Laboratory Techniques; Erythrocytes; | 1978 |
13 other studies available for methylmalonic acid and Anemia, Macrocytic
| Article | Year |
|---|---|
Test utilization for the diagnosis of vitamin B12 and folate deficiency in local clinics in Korea.
Topics: Adult; Anemia, Macrocytic; Blood Chemical Analysis; Erythrocyte Indices; Folic Acid; Folic Acid Defi | 2020 |
Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors.
Topics: Aged; Aging; Anemia; Anemia, Macrocytic; Blood Cell Count; Cognition; Cognition Disorders; Cystatin | 2010 |
Parenteral vitamin B12 in macrocytic hemodialysis patients reduced MMA levels but did not change mean red cell volume or hemoglobin.
Topics: Aged; Aged, 80 and over; Anemia, Macrocytic; Biomarkers; Chi-Square Distribution; Erythrocyte Indice | 2011 |
Methylmalonic acid excretion: an index of vitamin-B12 deficiency.
Topics: Anemia; Anemia, Macrocytic; Humans; Malonates; Methylmalonic Acid; Vitamin B 12 Deficiency; Vitamins | 1962 |
METHYLMALONIC ACID EXCRETION AND VITAMIN B12 DEFICIENCY IN THE HUMAN.
Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Carcinoma; Celiac Disease; Chromatography; Crohn Dis | 1964 |
West syndrome in an infant with vitamin B12 deficiency in the absence of macrocytic anaemia.
Topics: Anemia, Macrocytic; Brain; Diagnosis, Differential; Electroencephalography; Female; Homocysteine; Hu | 2007 |
Etiology and diagnostic evaluation of macrocytosis.
Topics: Adult; Aged; Alcohol Drinking; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Diseases; Diag | 2000 |
[Water-soluble vitamins in therapy: cobalamins].
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Cobamides; Humans; Malonates; Metabolism, Inborn Errors; | 1977 |
Erythrocyte glutathione metabolism in cobalt-deficient goats.
Topics: Anemia, Macrocytic; Animal Feed; Animals; Cobalt; Erythrocytes; Female; Glutathione; Glutathione Per | 1976 |
[Assessment of laboratory findings in megaloblastic anemia--measurement of serum vitamin B12 and methylmalonic acid].
Topics: Adult; Aged; Aged, 80 and over; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Humans; Male; Mal | 1989 |
[Urinary methylmalonic acid excretion and clinical features in megaloblastic anemia due to vitamin B12 deficiency].
Topics: Adolescent; Adult; Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Humans; Male; Malonates; | 1989 |
A cobalamin metabolic defect with homocystinuria, methylmalonic aciduria and macrocytic anemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Metabolism, Inborn Errors; Ane | 1986 |
Vitamin B12-responsive megaloblastic anemia, homocystinuria, and transient methylmalonic aciduria in cb1E disease.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Fibroblasts; Homocystinuria; Humans; Infant, Newborn; Mal | 1988 |