methylmalonic acid has been researched along with Addison's Anemia in 21 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The full syndrome of a vitamin B12 deficiency is rather simple to diagnose." | 6.39 | [Low serum vitamin B 12 level and vitamin B 12 deficiency in the elderly. When should supplement be provided?]. ( de Rooij, S; Hooijer, C; Thijssen, C; van Bruggen, R, 1994) |
| "The full syndrome of a vitamin B12 deficiency is rather simple to diagnose." | 2.39 | [Low serum vitamin B 12 level and vitamin B 12 deficiency in the elderly. When should supplement be provided?]. ( de Rooij, S; Hooijer, C; Thijssen, C; van Bruggen, R, 1994) |
| "Thereby, the underlying pernicious anemia was masked." | 1.35 | [Thromboembolic events, abortions and a sick infant--unusual presentation of a vitamin deficiency]. ( Driever, PH; Hennermann, JB; Massenkeil, G; Sturm, I; von Arnim-Baas, A, 2008) |
| "Previous reports on pernicious anemia treatment suggested that high folic acid intake adversely influences the natural history of vitamin B-12 deficiency, which affects many elderly individuals." | 1.35 | Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency. ( Jacques, PF; Morris, MS; Rosenberg, IH; Selhub, J, 2009) |
| "Autoimmune pernicious anemia was identified in 6 (50%) of 12 Cbl-deficient patients with normal serum Cbl levels." | 1.32 | Challenges in the identification of cobalamin-deficiency polyneuropathy. ( Barohn, RJ; Bryan, WW; Gronseth, GS; Herbelin, LL; Nations, SP; Saperstein, DS; Wolfe, GI, 2003) |
| "Neurological dysfunction due to vitamin B12 deficiency is most prominent in patients with mild to moderate anaemia." | 1.29 | Vitamin B12 deficiency is the primary cause of megaloblastic anaemia in Zimbabwe. ( Bennie, A; Gangaidzo, I; Gwanzura, C; Kiire, C; Lindenbaum, J; Moyo, A; Mudenge, B; Mukiibi, JM; Savage, D; Sitima, J, 1994) |
| "Some patients with pernicious anemia who were intermittently treated with cyanocobalamin were found to have elevated serum levels of methylmalonic acid while free of hematologic and neurologic abnormalities." | 1.27 | Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry. ( Allen, RH; Lindenbaum, J; Marcell, PD; Podell, ER; Stabler, SP, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (14.29) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Mazokopakis, EE | 1 |
| Richterman, A | 1 |
| Vaidya, A | 1 |
| Brown, JM | 1 |
| Braun, DA | 1 |
| Samuels, MA | 1 |
| Rojas Hernandez, CM | 1 |
| Oo, TH | 1 |
| Wainwright, P | 1 |
| Narayanan, S | 1 |
| Cook, P | 1 |
| Kamoun, F | 1 |
| Guirat, R | 1 |
| Megdich, F | 1 |
| Ben Ameur, S | 1 |
| Kallel, C | 1 |
| Hachicha, M | 1 |
| Sturm, I | 1 |
| Hennermann, JB | 1 |
| von Arnim-Baas, A | 1 |
| Driever, PH | 1 |
| Massenkeil, G | 1 |
| Selhub, J | 1 |
| Morris, MS | 1 |
| Jacques, PF | 1 |
| Rosenberg, IH | 1 |
| Carmel, R | 1 |
| Bellevue, R | 1 |
| Kelman, Z | 1 |
| Tweet, MS | 1 |
| Polga, KM | 1 |
| Stabler, SP | 2 |
| Ward, PC | 1 |
| Saperstein, DS | 1 |
| Wolfe, GI | 1 |
| Gronseth, GS | 1 |
| Nations, SP | 1 |
| Herbelin, LL | 1 |
| Bryan, WW | 1 |
| Barohn, RJ | 1 |
| WHITE, AM | 1 |
| COX, EV | 1 |
| Campbell, CD | 1 |
| Ganesh, J | 1 |
| Ficicioglu, C | 1 |
| Wellmer, J | 1 |
| Sturm, KU | 1 |
| Herrmann, W | 1 |
| Hoever, J | 1 |
| Klockgether, T | 1 |
| Linnebank, M | 1 |
| Savage, D | 1 |
| Gangaidzo, I | 1 |
| Lindenbaum, J | 3 |
| Kiire, C | 1 |
| Mukiibi, JM | 1 |
| Moyo, A | 1 |
| Gwanzura, C | 1 |
| Mudenge, B | 1 |
| Bennie, A | 1 |
| Sitima, J | 1 |
| de Rooij, S | 1 |
| van Bruggen, R | 1 |
| Thijssen, C | 1 |
| Hooijer, C | 1 |
| Scalabrino, G | 1 |
| Buccellato, FR | 1 |
| Tredici, G | 1 |
| Morabito, A | 1 |
| Lorenzini, EC | 1 |
| Allen, RH | 2 |
| Bächli, E | 1 |
| Fehr, J | 1 |
| Marcell, PD | 1 |
| Podell, ER | 1 |
| Silberstein, EP | 1 |
| Wilson, RG | 1 |
| Scurlock, JM | 1 |
5 reviews available for methylmalonic acid and Addison's Anemia
| Article | Year |
|---|---|
Advances in mechanisms, diagnosis, and treatment of pernicious anemia.
Topics: Aged; Algorithms; Anemia, Pernicious; Autoimmune Diseases; Decision Support Systems, Clinical; Dieta | 2015 |
Clinical practice. Vitamin B12 deficiency.
Topics: Administration, Oral; Anemia, Pernicious; Child; Child Nutrition Disorders; Diagnostic Errors; Femal | 2013 |
Modern approaches to the investigation of vitamin B12 deficiency.
Topics: Anemia, Pernicious; Antibodies, Blocking; Gastrins; Humans; Intrinsic Factor; Methylmalonic Acid; Pa | 2002 |
[Low serum vitamin B 12 level and vitamin B 12 deficiency in the elderly. When should supplement be provided?].
Topics: Aged; Anemia, Pernicious; Central Nervous System Diseases; Deoxyuridine; Humans; Methylmalonic Acid; | 1994 |
[Diagnosis of vitamin B12 deficiency: only apparently child's play].
Topics: Aging; Anemia, Pernicious; Blood Cell Count; Diagnosis, Differential; Folic Acid Deficiency; Gastrit | 1999 |
16 other studies available for methylmalonic acid and Addison's Anemia
| Article | Year |
|---|---|
Normal serum cobalamin levels do not exclude the diagnosis of pernicious anaemia: a case report.
Topics: Anemia, Pernicious; Female; Folic Acid Deficiency; Gastritis, Atrophic; Homocysteine; Humans; Hydrox | 2020 |
In the Balance.
Topics: Aged; Anemia, Pernicious; Brain; Cognitive Dysfunction; Diagnosis, Differential; Humans; Injections, | 2018 |
False-normal vitamin B12 results in a patient with pernicious anaemia.
Topics: Anemia, Pernicious; Diagnostic Errors; False Positive Reactions; Female; Homocysteine; Humans; Immun | 2015 |
Frequent Infections, Hypotonia, and Anemia in a Breastfed Infant.
Topics: Adult; Agammaglobulinemia; Anemia, Megaloblastic; Anemia, Pernicious; Asymptomatic Diseases; Breast | 2017 |
[Thromboembolic events, abortions and a sick infant--unusual presentation of a vitamin deficiency].
Topics: Abortion, Habitual; Adult; Anemia, Pernicious; Autoimmune Diseases; Breast Feeding; Diagnosis, Diffe | 2008 |
Folate-vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Aging; Anemia, Pernicious; Cognition Diso | 2009 |
Low cobalamin levels associated with sickle cell disease: Contrasting origins and clinical meanings in two instructive patients.
Topics: Adult; Anemia, Pernicious; Anemia, Sickle Cell; Autoantibodies; Depression; Female; Folic Acid; Gast | 2010 |
44-year-old man with shortness of breath, fatigue, and paresthesia.
Topics: Adult; Anemia, Pernicious; Blood Cell Count; Diagnosis, Differential; Dyspnea; Fatigue; Humans; Male | 2010 |
Challenges in the identification of cobalamin-deficiency polyneuropathy.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Pernicious; Female; Follow-Up Studies; Homocysteine; Humans; | 2003 |
METHYLMALONIC ACID EXCRETION AND VITAMIN B12 DEFICIENCY IN THE HUMAN.
Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Carcinoma; Celiac Disease; Chromatography; Crohn Dis | 1964 |
Two newborns with nutritional vitamin B12 deficiency: challenges in newborn screening for vitamin B12 deficiency.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; Anemia, Pernicious; Autoimmune Diseases; Biomarkers; Carnitine; | 2005 |
[Oral treatment of vitamin B12 deficiency in subacute combined degeneration].
Topics: Administration, Oral; Adult; Anemia, Pernicious; Autoantibodies; Dose-Response Relationship, Drug; F | 2006 |
Vitamin B12 deficiency is the primary cause of megaloblastic anaemia in Zimbabwe.
Topics: Anemia, Megaloblastic; Anemia, Pernicious; Erythrocyte Indices; Female; Folic Acid; Folic Acid Defic | 1994 |
Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Pernicious; Animals; Bacteria, An | 1997 |
Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry.
Topics: Adolescent; Adult; Aged; Anemia, Pernicious; Female; Folic Acid; Gas Chromatography-Mass Spectrometr | 1986 |
Methylmalonic aciduria in an infant of a mother with undiagnosed pernicious anaemia.
Topics: Anemia, Pernicious; Female; Humans; Infant, Newborn; Male; Malonates; Methylmalonic Acid; Vitamin B | 1987 |