methylmalonic acid has been researched along with Acute Disease in 12 studies
Methylmalonic Acid: A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.
methylmalonic acid : A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In propionic aciduria and methylmalonic aciduria, hyperammonemia as a symptom of metabolic decompensation is one of the major clinical problems." | 7.76 | N-carbamylglutamate in emergency management of hyperammonemia in neonatal acute onset propionic and methylmalonic aciduria. ( Donati, MA; Filippi, L; Fiorini, P; Gozzini, E; la Marca, G; Malvagia, S, 2010) |
| "To evaluate whether low levels of holotranscobalamin (holoTC) or elevated levels of methylmalonic acid (MMA), both indicators of vitamin B(12) deficiency, might predispose to new cardiovascular events following an acute myocardial infarction (MI)." | 7.74 | Holotranscobalamin and methylmalonic acid as prognostic markers following an acute myocardial infarction. ( Aarsetøy, H; Grundt, H; Mansoor, MA; Nilsen, DW; Reine, A; Valente, E, 2008) |
| "Metabolic acidosis is known to be associated with increased blood potassium and phosphorus concentrations but the influence of mineral versus nonmineral acids on these variables remains undefined." | 7.66 | Relationship between blood pH and potassium and phosphorus during acute metabolic acidosis. ( Oster, JR; Perez, GO; Vaamonde, CA, 1978) |
| "In propionic aciduria and methylmalonic aciduria, hyperammonemia as a symptom of metabolic decompensation is one of the major clinical problems." | 3.76 | N-carbamylglutamate in emergency management of hyperammonemia in neonatal acute onset propionic and methylmalonic aciduria. ( Donati, MA; Filippi, L; Fiorini, P; Gozzini, E; la Marca, G; Malvagia, S, 2010) |
| "To evaluate whether low levels of holotranscobalamin (holoTC) or elevated levels of methylmalonic acid (MMA), both indicators of vitamin B(12) deficiency, might predispose to new cardiovascular events following an acute myocardial infarction (MI)." | 3.74 | Holotranscobalamin and methylmalonic acid as prognostic markers following an acute myocardial infarction. ( Aarsetøy, H; Grundt, H; Mansoor, MA; Nilsen, DW; Reine, A; Valente, E, 2008) |
| " Five had methylmalonic acidemia, three had isovaleric acidemia, and one had maple syrup urine disease." | 3.69 | Pancreatitis in patients with organic acidemias. ( Bonham, J; Clarke, JT; Durie, P; Kahler, SG; Lawless, ST; Leonard, JV; Sherwood, WG; Taylor, CJ; Woolf, D; Zaritsky, A, 1994) |
| "A 1-year-old boy with a typical B12-responsive form of methylmalonic acidaemia was hospitalized twice due to acute bacterial infections." | 3.66 | Excretion pattern of branched-chain amino acid metabolites during the course of acute infections in a patient with methylmalonic acidaemia. ( Christensen, E; Gregersen, N; Kølvraa, S; Rasmussen, K, 1980) |
| "Metabolic acidosis is known to be associated with increased blood potassium and phosphorus concentrations but the influence of mineral versus nonmineral acids on these variables remains undefined." | 3.66 | Relationship between blood pH and potassium and phosphorus during acute metabolic acidosis. ( Oster, JR; Perez, GO; Vaamonde, CA, 1978) |
| "We observed 1176 episodes of acute lower respiratory tract infections." | 1.34 | Folate, but not vitamin B-12 status, predicts respiratory morbidity in north Indian children. ( Bahl, R; Bhan, MK; Bhandari, N; Gjessing, HK; Refsum, H; Schneede, J; Sommerfelt, H; Strand, TA; Taneja, S; Ueland, PM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Filippi, L | 1 |
| Gozzini, E | 1 |
| Fiorini, P | 1 |
| Malvagia, S | 1 |
| la Marca, G | 1 |
| Donati, MA | 1 |
| Aarsetøy, H | 1 |
| Valente, E | 1 |
| Reine, A | 1 |
| Mansoor, MA | 1 |
| Grundt, H | 1 |
| Nilsen, DW | 1 |
| Strand, TA | 1 |
| Taneja, S | 1 |
| Bhandari, N | 1 |
| Refsum, H | 1 |
| Ueland, PM | 1 |
| Gjessing, HK | 1 |
| Bahl, R | 1 |
| Schneede, J | 1 |
| Bhan, MK | 1 |
| Sommerfelt, H | 1 |
| Giardini, O | 1 |
| Marzetti, G | 1 |
| Lubrano, R | 1 |
| Laurenti, F | 1 |
| Martino, F | 1 |
| Mannarino, O | 1 |
| D'Eufemia, P | 1 |
| Ruberto, U | 1 |
| Kølvraa, S | 1 |
| Gregersen, N | 1 |
| Christensen, E | 1 |
| Rasmussen, K | 2 |
| Oster, JR | 2 |
| Perez, GO | 2 |
| Canterbury, JM | 1 |
| Alpert, HC | 1 |
| Vaamonde, CA | 2 |
| Kahler, SG | 1 |
| Sherwood, WG | 1 |
| Woolf, D | 1 |
| Lawless, ST | 1 |
| Zaritsky, A | 1 |
| Bonham, J | 1 |
| Taylor, CJ | 1 |
| Clarke, JT | 1 |
| Durie, P | 1 |
| Leonard, JV | 1 |
| Treacy, E | 1 |
| Arbour, L | 1 |
| Chessex, P | 1 |
| Graham, G | 1 |
| Kasprzak, L | 1 |
| Casey, K | 1 |
| Bell, L | 1 |
| Mamer, O | 1 |
| Scriver, CR | 1 |
| Baumgartner, ER | 1 |
| Bachmann, C | 1 |
| Brechbühler, T | 1 |
| Wick, H | 1 |
| Hagelskjaer, L | 1 |
| Royer, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Routine Administration of Folic Acid and Vitamin B12 to Prevent Childhood Infections in Young Indian Children[NCT00717730] | Phase 2 | 1,000 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 other studies available for methylmalonic acid and Acute Disease
| Article | Year |
|---|---|
N-carbamylglutamate in emergency management of hyperammonemia in neonatal acute onset propionic and methylmalonic aciduria.
Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Ammonia; Emergency Medical Services; Female; Gl | 2010 |
Holotranscobalamin and methylmalonic acid as prognostic markers following an acute myocardial infarction.
Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Female; Follow-Up Studies; Homocysteine; Humans; | 2008 |
Folate, but not vitamin B-12 status, predicts respiratory morbidity in north Indian children.
Topics: Acute Disease; Child, Preschool; Cohort Studies; Female; Folic Acid; Homocysteine; Humans; Incidence | 2007 |
[The neonatal acute form of methylmalonic acidemia. Report of 2 clinical cases].
Topics: Acidosis; Acute Disease; Amino Acid Metabolism, Inborn Errors; Female; Humans; Hyperglycemia; Infant | 1980 |
Excretion pattern of branched-chain amino acid metabolites during the course of acute infections in a patient with methylmalonic acidaemia.
Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Bacterial Infectio | 1980 |
Plasma parathyroid hormone and divalent cation response to induction of acute metabolic acidosis.
Topics: Acidosis; Acute Disease; Animals; Bicarbonates; Calcium; Dogs; Female; Hematocrit; Lactates; Lactic | 1982 |
Pancreatitis in patients with organic acidemias.
Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chronic Disease; Femal | 1994 |
Glutathione deficiency as a complication of methylmalonic acidemia: response to high doses of ascorbate.
Topics: Acidosis, Lactic; Acute Disease; Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Child; Glutath | 1996 |
Relationship between blood pH and potassium and phosphorus during acute metabolic acidosis.
Topics: Acidosis; Acute Disease; Animals; Bicarbonates; Blood; Carbon Dioxide; Chlorides; Dogs; Female; Hydr | 1978 |
Acute neonatal nonketotic hyperglycinemia: normal propionate and methylmalonate metabolism.
Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Coenzyme A; Female; Fi | 1975 |
Methylmalonic acid concentration in serum not affected in hepatic disease.
Topics: Acute Disease; Adult; Aged; Female; Hepatitis; Hepatitis, Chronic; Humans; Liver Cirrhosis; Liver Di | 1992 |
Hyperuricemia in children, with the exception of the Lesch-Nyhan syndrome.
Topics: Acidosis; Acute Disease; Acute Kidney Injury; Adult; Child; Child, Preschool; Chronic Disease; Femal | 1974 |