methyllycaconitine and Disease Models, Animal

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Caspase 3; Caspase Inhibitors; Central Nervous System Stimulants; Cholinergic Neurons; Colitis, Ulcerative; Colon; Dendritic Cells; Deoxyglucose; Disease Models, Animal; Enzyme Inhibitors; Janus Kinase 2; Mice, Inbred BALB C; Neuroimmunomodulation; Neuropeptides; Nicotine; Oxazolone; rac1 GTP-Binding Protein; STAT3 Transcription Factor; Th2 Cells; Tyrphostins; Vagus Nerve

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Cognitive Dysfunction; Diffuse Axonal Injury; Disease Models, Animal; Learning; Male; Maze Learning; Memory; Rats; Rats, Sprague-Dawley

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Asphyxia; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Heart Arrest; Hippocampus; Humans; Hypoxia, Brain; Ischemic Postconditioning; Male; Neuroprotection; NF-kappa B; Quinuclidines; Rats; Signal Transduction; STAT3 Transcription Factor; Treatment Outcome

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cells, Cultured; Concanavalin A; Disease Models, Animal; Hepatitis, Autoimmune; Humans; Kupffer Cells; Liver; Male; Mice; NF-kappa B; Nicotine; Primary Cell Culture; Protective Agents; Signal Transduction

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Blood Pressure; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Electrocardiography; Heart Failure; Hemodynamics; Male; Myocardial Infarction; Nicotinic Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Depression; Disease Models, Animal; Kynurenic Acid; Kynurenine 3-Monooxygenase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Prefrontal Cortex

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Disease Models, Animal; Dopamine Uptake Inhibitors; Memory Consolidation; Mental Recall; Nicotinic Antagonists; Prefrontal Cortex; Rats; Rats, Wistar

Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Atrial Fibrillation; Cardiac Pacing, Artificial; Case-Control Studies; Disease Models, Animal; Dogs; Heart Atria; Interleukin-6; Neuroimmunomodulation; NF-kappa B; Nicotinic Antagonists; Pulmonary Veins; Refractory Period, Electrophysiological; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha; Vagus Nerve; Vagus Nerve Stimulation

Topics: Aconitine; Alzheimer Disease; Amyloid beta-Peptides; Animals; CARD Signaling Adaptor Proteins; Cognition; Diet, Western; Disease Models, Animal; Hippocampus; Humans; Inflammasomes; Inflammation; Insulin Resistance; Interleukin-18; Lipopolysaccharides; Microglia; Palonosetron; Peptide Fragments; Pyroptosis; Rats; Receptors, Serotonin, 5-HT3; Risk Factors; Spatial Memory

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antidepressive Agents; Calcium-Binding Proteins; Cholinergic Agents; Depressive Disorder; Disease Models, Animal; Hippocampus; Inflammation; Isoxazoles; Lipopolysaccharides; Male; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Motor Activity; Phenylurea Compounds; Prefrontal Cortex

Topics: Aconitine; Administration, Inhalation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Emphysema; Mice, Inbred C57BL; Nicotinic Agonists; Pancreatic Elastase; Pulmonary Alveoli; Smoking Cessation; Varenicline

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apoptosis; Benzamides; Bridged Bicyclo Compounds; Capsaicin; Disease Models, Animal; Down-Regulation; Humans; Lung; Lung Injury; Male; Mice; Mice, Knockout; Reperfusion Injury; Treatment Outcome; TRPV Cation Channels

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cognition; Disease Models, Animal; Glutamic Acid; Hippocampus; Humans; Long-Term Potentiation; Memory; Nicotinic Antagonists; Rats; Receptors, Nicotinic

Topics: Aconitine; Androstadienes; Animals; beta Catenin; Blood-Brain Barrier; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Hemorrhage; Claudin-3; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mice; Mice, Inbred Strains; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinuclidines; Receptors, Nicotinic; Signal Transduction; Wortmannin

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Bupivacaine; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Male; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, Knockout; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Necrosis; Nicotinic Agonists; Nicotinic Antagonists; Regeneration

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Aspartate Aminotransferases; Chemokine CCL2; Disease Models, Animal; Disease Progression; Epithelium; Hepatocytes; Liver; Liver Cirrhosis, Biliary; Male; Myofibroblasts; Nicotinic Antagonists; Rats, Sprague-Dawley; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Vagotomy; Vagus Nerve

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apolipoproteins E; Benzazepines; Body Weight; Cardiovascular Diseases; Cholesterol; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotinic Agonists; Plaque, Atherosclerotic; Quinoxalines; Varenicline

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Indoles; Inflammation Mediators; Male; Mice, Inbred ICR; Peroxidase; Tropisetron

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cholinesterase Inhibitors; Cognition Disorders; Disease Models, Animal; Galantamine; Gene Expression Regulation; Male; Maze Learning; Mice; Mice, Inbred BALB C; Nicotinic Agonists; Nicotinic Antagonists; Peptide Fragments; Psychomotor Performance; Quinuclidines; RNA, Messenger; Time Factors

Topics: Aconitine; Adjuvants, Immunologic; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apolipoproteins E; Arthritis, Experimental; Bridged-Ring Compounds; Cell Movement; Cell Proliferation; Disease Models, Animal; Disease Progression; Freund's Adjuvant; Inflammation; Injections, Intra-Articular; Lipopolysaccharides; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nicotinic Antagonists; Peptide Fragments; Pyrroles; Spiro Compounds; Xanthones

Topics: Aconitine; Adrenergic alpha-2 Receptor Agonists; alpha7 Nicotinic Acetylcholine Receptor; Animals; Astrocytes; Dexmedetomidine; Disease Models, Animal; Encephalitis; Hippocampus; Interleukin-1beta; Male; Microglia; Neuroprotective Agents; NF-kappa B; Rats; Rats, Sprague-Dawley; Tibial Fractures; Tumor Necrosis Factor-alpha

Topics: Acetylcholine; Aconitine; Animals; Circadian Rhythm; Corticosterone; Cytokines; Disease Models, Animal; Hormone Antagonists; Inflammation; Kidney; Lipopolysaccharides; Liver; Mice; Mice, Inbred C57BL; Mifepristone; Nicotinic Antagonists; Vesicular Acetylcholine Transport Proteins

Topics: Aconitine; Adult; alpha7 Nicotinic Acetylcholine Receptor; Animals; Ascitic Fluid; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Endometriosis; Endometrium; Female; Gene Expression Regulation; Humans; Interleukin-1beta; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Nicotine; Primary Cell Culture; Quinuclidines; RNA, Messenger; Severity of Illness Index; Signal Transduction

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Agents; Chronic Pain; Comorbidity; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Neuroglia; Quinuclidines; Random Allocation; Rats, Sprague-Dawley; Spinal Cord; Stress Disorders, Post-Traumatic; Touch

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Dihydro-beta-Erythroidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Immobility Response, Tonic; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Swimming; Zebrafish; Zebrafish Proteins

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cytidine Diphosphate Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Inflammation; Injections; Male; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Time Factors; Tumor Necrosis Factor-alpha

Topics: Aconitine; Adrenergic beta-Antagonists; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Cell Line; Disease Models, Animal; Immune Tolerance; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Nicotinic Agonists; Nicotinic Antagonists; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Pulmonary Edema; Receptors, Nicotinic; Signal Transduction

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Disease Progression; Kidney Diseases; Male; NADPH Oxidase 4; NADPH Oxidases; Nephrectomy; Nicotine; Nicotinic Antagonists; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Transforming Growth Factor beta

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Dihydro-beta-Erythroidine; Disease Models, Animal; Drug Delivery Systems; Hippocampus; Male; Maze Learning; Memory Disorders; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Nicotinic; Stress, Psychological; Time Factors

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Cell Survival; Corticosterone; Disease Models, Animal; Drug Interactions; Hippocampus; In Vitro Techniques; Male; Mifepristone; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic

Topics: Aconitine; Acute Disease; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Atropine; Bungarotoxins; Central Nervous System; Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Inflammation; Mice; Morphine; Muscarinic Antagonists; Nicotinic Antagonists; Nociceptors; Pain; Pain Measurement; Reaction Time; Receptors, Nicotinic

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Auditory Perceptual Disorders; Disease Models, Animal; Drug Interactions; Evoked Potentials, Auditory; Indoles; Male; Mice; Mice, Inbred DBA; Nicotinic Antagonists; Receptors, Nicotinic; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Time Factors; Tropisetron

Topics: Aconitine; Analysis of Variance; Animals; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Neurotoxicity Syndromes; Nicotinic Agonists; Nicotinic Antagonists; Radioligand Assay; Reactive Oxygen Species; Receptors, Nicotinic; Synaptosomes; Tritium

Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Cocaine; Disease Models, Animal; Drug Tolerance; Exploratory Behavior; Female; Male; Maze Learning; Mecamylamine; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotinic Antagonists; Receptors, Nicotinic; Substance Withdrawal Syndrome

Topics: Aconitine; Animals; Behavior, Animal; Brain; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Male; Nicotine; Nicotinic Antagonists; Rats; Rats, Wistar; Reward; Self Administration; Substance Withdrawal Syndrome; Tobacco Use Disorder