Page last updated: 2024-08-17

methylene blue and Tauopathies

methylene blue has been researched along with Tauopathies in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (90.91)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Mahajan, S; Mudher, A; Rouiz Ortega, ED; Skoulakis, EMC; Vourkou, E1
Csizmadia, G; Keresztes, A; Kiss, R; Mandelkow, E; Pickhardt, M; Solti, K; Tóth, G; Zhu, M1
Carlson, GA; Friedman, T; Hyman, BT; Pitstick, R; Polydoro, M; Roe, A; Spires-Jones, TL1
Beal, MF; Dumont, M; Elipenahli, C; Gerges, M; Jainuddin, S; Jové, M; Kaidery, NA; Launay, N; Portero-Otin, M; Pujol, A; Stack, C; Starkov, AA; Starkova, N; Tampellini, D; Thomas, B1
Close, SP; Davidson, K; Deiana, S; Dietze, S; Goatman, EA; Goatman, K; Harrington, CR; Harrington, KA; Horsley, D; Magbagbeolu, M; Melis, V; Rickard, JE; Riedel, G; Schwab, K; Stamer, K; Storey, JM; Theuring, F; Wischik, CM; Zabke, C1
Cadinu, D; Goll, P; Hochgräfe, K; Könen, S; Mandelkow, E; Mandelkow, EM; Matenia, D; Morellini, F; Petrova, O; Pickhardt, M; Sydow, A1
Omata, Y; Sheik Mohideen, S; Tsuda, L; Yamasaki, Y; Yoshiike, Y1
Binder, L; Bonnefoy, E; Buée, L; Chauderlier, A; Chouala, MS; Delattre, L; Galas, MC; Humez, S; Kayed, R; Lefebvre, B; Marciniak, E; Sultan, A; Tardivel, M; Violet, M1
Haass, C; Hruscha, A; Paquet, D; Schmid, B; van Bebber, F1
Congdon, EE; Dickey, CA; Duff, KE; Figueroa, YH; Gestwicki, JE; Herman, M; Marinec, PS; Myeku, N; Wu, JW; Yu, WH1
Baumeister, R; Biernat, J; Fatouros, C; Koushika, SP; Mandelkow, E; Mandelkow, EM; Pir, GJ; Schmidt, E1

Other Studies

11 other study(ies) available for methylene blue and Tauopathies

ArticleYear
Human Tau Aggregates Are Permissive to Protein Synthesis-Dependent Memory in
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023, 04-19, Volume: 43, Issue:16

    Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Drosophila; Humans; Memory Disorders; Methylene Blue; tau Proteins; Tauopathies

2023
Structural Basis of Small Molecule Targetability of Monomeric Tau Protein.
    ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12

    Topics: Humans; Intrinsically Disordered Proteins; Methylene Blue; Molecular Docking Simulation; Molecular Targeted Therapy; Neurofibrillary Tangles; Protein Structure, Tertiary; tau Proteins; Tauopathies

2018
Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy.
    Neuroscience letters, 2014, Mar-06, Volume: 562

    Topics: Amyloid beta-Peptides; Animals; Disease Models, Animal; Female; Male; Methylene Blue; Mice; Mice, 129 Strain; Mice, Transgenic; Neurofibrillary Tangles; tau Proteins; Tauopathies

2014
Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity.
    Human molecular genetics, 2014, Jul-15, Volume: 23, Issue:14

    Topics: Animals; Behavior, Animal; Cell Line; Female; Gene Expression Regulation; Humans; Methylene Blue; Mice; Mice, Transgenic; Mitochondria; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Sex Factors; Signal Transduction; tau Proteins; Tauopathies

2014
Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models.
    Behavioural pharmacology, 2015, Volume: 26, Issue:4

    Topics: Animals; Brain; Cohort Studies; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Learning Disabilities; Maze Learning; Methylene Blue; Mice, Transgenic; Motor Activity; Neurons; Neuroprotective Agents; Oxidation-Reduction; Problem Solving; Random Allocation; Tauopathies

2015
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.
    Acta neuropathologica communications, 2015, May-10, Volume: 3

    Topics: Animals; Behavior, Animal; Cognition; Cognition Disorders; Disease Models, Animal; Enzyme Inhibitors; Humans; Maze Learning; Memory; Methylene Blue; Mice; Mice, Inbred C57BL; Mice, Transgenic; tau Proteins; Tauopathies; Time Factors; Treatment Outcome

2015
Nontoxic singlet oxygen generator as a therapeutic candidate for treating tauopathies.
    Scientific reports, 2015, Jun-01, Volume: 5

    Topics: Animals; Animals, Genetically Modified; Autophagy; Behavior, Animal; Disease Models, Animal; Drosophila; Female; Humans; Male; Methylene Blue; Oxidative Stress; Singlet Oxygen; Solubility; tau Proteins; Tauopathies

2015
Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo.
    Neurobiology of disease, 2015, Volume: 82

    Topics: Animals; Cell Death; Cell Nucleus; Cytoplasm; Disease Models, Animal; DNA Breaks; Female; Fever; Hippocampus; Humans; Methylene Blue; Mice, Transgenic; Neurons; Neuroprotective Agents; Oxidative Stress; Protein Multimerization; RNA; tau Proteins; Tauopathies

2015
Methylene blue fails to inhibit Tau and polyglutamine protein dependent toxicity in zebrafish.
    Neurobiology of disease, 2010, Volume: 39, Issue:3

    Topics: Animals; Animals, Genetically Modified; Axons; Blotting, Western; Cell Death; Fluorescent Antibody Technique; Methylene Blue; Neurons; Peptides; Phosphorylation; tau Proteins; Tauopathies; Zebrafish

2010
Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo.
    Autophagy, 2012, Volume: 8, Issue:4

    Topics: Animals; Autophagy; Biomarkers; Brain; Cells, Cultured; CHO Cells; Cricetinae; Gene Knockdown Techniques; Humans; Lysosomes; Methylene Blue; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Models, Biological; Neurons; Phosphorylation; Protein Transport; tau Proteins; Tauopathies; Vacuoles

2012
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity.
    Human molecular genetics, 2012, Aug-15, Volume: 21, Issue:16

    Topics: Animals; Animals, Genetically Modified; Axonal Transport; Blood-Brain Barrier; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Humans; Hydrazines; Methylene Blue; Mitochondria; Motor Neurons; Mutation; Neurons; Neuroprotective Agents; Phenotype; Phosphorylation; Protein Structure, Tertiary; Sensory Receptor Cells; tau Proteins; Tauopathies; Thiazoles; Vesicle-Associated Membrane Protein 1

2012