Page last updated: 2024-08-17

methylene blue and Shock, Septic

methylene blue has been researched along with Shock, Septic in 66 studies

Research

Studies (66)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	20 (30.30)	18.2507
2000's	12 (18.18)	29.6817
2010's	15 (22.73)	24.3611
2020's	19 (28.79)	2.80

Authors

Authors	Studies
Allam, R; Awad, H; Ibrahim, M; Ismail, R; Shehata, B; Youssef, O	1
Chen, G; Lou, X; Xue, J	1
Auxiliadora-Martins, M; Basile-Filho, A; Becari, C; Evora, PRB; Luis-Silva, F; Martins-Filho, OA; Menegueti, MG; Peres, LM; Petroski-Moraes, BC; Sato, L; Sepeda, CDR	1
Caqui, P; Coronado Munoz, AJ; Domínguez-Rojas, JA; Sanchez, A	1
Albertson, TE; Chenoweth, JA; Lewis, JC; Morrissey, BM; Pugashetti, JV; Sandrock, CE	1
Albuquerque, AAS; de Castro, RSAP; Evora, PRB; Ferreira, CHF; Gonçalves-Ferri, WA; Oharomari, LK; Silva Lessa, DF	1
Auxiliadora-Martins, M; Basile-Filho, A; Becari, C; Donadel, MD; Dos Reis Sepeda, C; Evora, PRB; Gallo, GB; Jordani, MC; Luis-Silva, F; Martins-Filho, OA; Menegueti, MG; Mestriner, F; Peres, LM; Petroski-Moraes, BC; Sato, L	1
Aguilera-González, P; Aguirre-Avalos, G; Chávez-Peña, Q; Gómez-Partida, CA; Hernández, G; Ibarra-Estrada, M; Kattan, E; López-Pulgarín, JA; Mijangos-Méndez, JC; Ortiz-Macías, IX; Rico-Jauregui, U; Sandoval-Plascencia, L	1
Czempik, PF; Krzych, ŁJ; Pluta, MP; Putowski, Z	1
Dubey, D; Imran, A; Ray, P	1
Aguirre-Avalos, G; Hernández, G; Ibarra-Estrada, M; Kattan, E	1
Evans, H; Ho, VP; Kaafarani, H; Namias, N; Rattan, R; Zakrison, TL	1
Sullivan, JB; Tchen, S	1
Burns, SL; Saha, BK	1
Brienza, N; Giglio, M; Paladini, A; Pasqualucci, A; Puntillo, F; Varrassi, G	1
Scigliano, G; Scigliano, GA	1
Bloom, A; Faisal, H; Gaber, AO	1
Dinis-Oliveira, RJ; Durão, C; Pedrosa, F	1
Annich, G; Ben-Ari, J; Bitterman, Y; Eytan, D; Hadash, A; Hubara, E	1
Clark, RF; Darracq, MA; Lo, JC	1
Fletcher, C; Le, N; Qawasmi, A; Roy, S; Udelhofen, K; Yadegarian, A; Zipkin, R	1
Dumbarton, TC; Farah, N; Lehmann, C; Maxan, A; Minor, S; Nantais, J; Zhou, J	1
Benner, K; Brown, B; Hayes, L; Prabhakaran, P; Rutledge, C	1
Fischer, GW; Hosseinian, L; Levin, MA; Weiner, M	1
Harding, SA; Hoffman, RS; Jang, DH	1
Smolinske, S; Tataru, AP; Warrick, BJ	1
Bopp, C; Burhenne, J; Flechtenmacher, C; Goeppert, B; Schirmacher, P; Warth, A	1
Binnekade, JM; Daemen-Gubbels, CR; de Jong, M; Groeneveld, AB; Juffermans, NP; Vervloet, MG	1
Mount, JC; Rowe, AS	1
Foudraine, N; Heemskerk, S; Pickkers, P; Sleigh, J; van der Hoeven, JG; van Haren, FM	1
Flynn, JD; Hatton, KW; McMahon Horner, D; Paciullo, CA	1
Marschalek, C; Schramm, W	1
Adrario, E; Donati, A; Pelaia, P; Preiser, JC	1
Dumbarton, TC; Green, R; Minor, S; Yeung, CK	1
Dumbarton, TC; Gorman, SK; Green, R; Loubani, O; Minor, S; White, F	1
Coltrinari, R; Conti, G; Donati, A; Loggi, S; Münch, C; Pelaia, P; Pietropaoli, P; Preiser, JC	1
Bjertnaes, LJ; Evgenov, OV	1
Da-Silva, SS; Sajan, IS; Underwood, JP	1
Mitaka, C	1
Holtby, H; Taylor, K	1
Kim, DS; Kim, WD; Kim, WS; Koh, Y; Lee, SD; Lim, CM; Park, BK; Shim, TS	1
Donati, A; Preiser, JC	1
Foudraine, NA; Heemskerk, S; Masereeuw, R; Peters, WH; Pickkers, P; Russel, FG; van der Hoeven, JG; van Haren, FM	1
Carlier, E; De Backer, D; Kahn, RJ; Leeman, M; Lejeune, P; Preiser, JC; Roman, A; Vincent, JL	1
Dellinger, RP; Hata, JS	1
Manikis, P; Metz, G; Preiser, JC; Rogiers, P; Spapen, H; Vincent, JL; Zhang, H	1
Marczin, N; Salzman, AL; Szabó, C; Tekeres, M	1
Schneider, F	1
Bronsveld, W; Daemen-Gubbels, CR; Groeneveld, AB; Groeneveld, PH; Thijs, LG; van Kamp, GJ	1
Francis, S; Keaney, JF; Loscalzo, J; Loscalzo, JF; Puyana, JC; Stamler, JS	1
Baker, CH; Sutton, ET	1
Koch, HJ	1
Bedos, JP; Gachot, B; Regnier, B; Veber, B; Wolff, M	1
Schreiber, MD	1
Carrion, V; Driscoll, W; Morin, FC; Steinhorn, RH; Thurin, S	1
Brown, G; Frankl, D; Phang, T	1
Andresen, M; Bugedo, G; Castillo, L; Dagnino, J; Dougnac, A; Espejo, J; Hernández, G; Letelier, LM	1
Chen, SJ; Wu, CC; Yen, MH	1
Alvarez, M; Andresen, M; Bugedo, G; Castillo, L; Dagnino, J; Díaz, O; Dougnac, A; Hernández, G	1
Brar, R; Dee, L; Khadour, F; Kumar, A; Parrillo, JE; Schulz, R; Skorupa, G; Wang, P	1
Azambuja, LA; Friedman, G; Oliveira, E; Oliveira, ES; Oliveira, RP; Sant'Anna, UL; Weingartner, R	1
Chang, MS; Chen, CC; Chen, SA; Chiang, CE; Ding, PY; Lin, YC; Luk, HN	1
Bjertnaes, LJ; Egorina, EM; Evgenov, NV; Evgenov, OV; Kirov, MY; Nedashkovsky, EV; Sovershaev, MA; Sveinbjørnsson, B	1
Bjertnaes, LJ; Evgenov, OV; Sveinbjørnsson, B	1
Hasselmann, M; Lutun, P; Schneider, F; Stoclet, JC; Tempé, JD	1
Berbiguier, N; Culo, F; Galey, L; Marusić, M; Sabolović, D; Somogyi, L	1

Reviews

13 review(s) available for methylene blue and Shock, Septic

Article	Year
[Research progress of methylene blue in the treatment of sepsis and septic shock]. Zhonghua wei zhong bing ji jiu yi xue, 2021, Volume: 33, Issue:11 Topics: Cyclic GMP; Guanylate Cyclase; Humans; Methylene Blue; Nitric Oxide; Sepsis; Shock, Septic	2021
The pharmacotherapeutic options in patients with catecholamine-resistant vasodilatory shock. Expert review of clinical pharmacology, 2022, Volume: 15, Issue:8 Topics: Angiotensin II; Ascorbic Acid; Cardiotonic Agents; Catecholamines; Cytomegalovirus Infections; Dobutamine; Humans; Hydroxocobalamin; Methylene Blue; Milrinone; Shock; Shock, Septic; Thiamine; Vasoconstrictor Agents; Vasopressins	2022
Successful Use of Methylene Blue in Catecholamine-Resistant Septic Shock: A Case Report and Short Literature Review. International journal of molecular sciences, 2023, Jun-28, Volume: 24, Issue:13 Topics: Catecholamines; Humans; Methylene Blue; Nitric Oxide Synthase; Shock; Shock, Septic	2023
Sepsis 2019: What Surgeons Need to Know. Surgical infections, 2020, Volume: 21, Issue:3 Topics: Acinetobacter baumannii; Acinetobacter Infections; Angiotensin II; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Carbapenem-Resistant Enterobacteriaceae; Drug Resistance, Multiple, Bacterial; Duration of Therapy; Enterobacteriaceae Infections; Enterococcus faecium; Enzyme Inhibitors; Gram-Positive Bacterial Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae; Machine Learning; Methicillin-Resistant Staphylococcus aureus; Methylene Blue; Organ Dysfunction Scores; Patient Care Bundles; Postoperative Complications; Practice Guidelines as Topic; Procalcitonin; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Shock, Septic; Staphylococcal Infections; Thiamine; Vancomycin-Resistant Enterococci; Vasoconstrictor Agents; Vitamin B Complex	2020
Clinical utility of midodrine and methylene blue as catecholamine-sparing agents in intensive care unit patients with shock. Journal of critical care, 2020, Volume: 57 Topics: Blood Pressure; Catecholamines; Critical Care; Critical Illness; Humans; Hypotension; Intensive Care Units; Methylene Blue; Midodrine; Off-Label Use; Patient Safety; Shock, Septic; Vasoconstrictor Agents	2020
The Story of Nitric Oxide, Sepsis and Methylene Blue: A Comprehensive Pathophysiologic Review. The American journal of the medical sciences, 2020, Volume: 360, Issue:4 Topics: Humans; Methylene Blue; Nitric Oxide; Shock, Septic; Vasodilation; Vasoplegia	2020
Vasopressor-Sparing Action of Methylene Blue in Severe Sepsis and Shock: A Narrative Review. Advances in therapy, 2020, Volume: 37, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Hemodynamics; Humans; Male; Methylene Blue; Microcirculation; Middle Aged; Sepsis; Shock, Septic; Vasoconstrictor Agents; Vasopressins	2020
A review of methylene blue treatment for cardiovascular collapse. The Journal of emergency medicine, 2014, Volume: 46, Issue:5 Topics: Anaphylaxis; Enzyme Inhibitors; Humans; Methylene Blue; Shock; Shock, Septic	2014
Methylene Blue: Magic Bullet for Vasoplegia? Anesthesia and analgesia, 2016, Volume: 122, Issue:1 Topics: Cardiac Surgical Procedures; Cardiovascular Agents; Hemodynamics; Humans; Liver Transplantation; Methylene Blue; Resuscitation; Shock, Septic; Treatment Outcome; Vasodilation; Vasoplegia	2016
Methylene blue for the treatment of septic shock. Pharmacotherapy, 2010, Volume: 30, Issue:7 Topics: Clinical Trials as Topic; Guanylate Cyclase; Hemodynamics; Humans; Lung; Methylene Blue; Nitric Oxide; Randomized Controlled Trials as Topic; Retrospective Studies; Shock, Septic; Vasodilation	2010
[Septic shock and NO]. Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 9 Topics: Animals; Biomarkers; Guanidines; Guanylate Cyclase; Hemodynamics; Humans; Methylene Blue; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; omega-N-Methylarginine; Receptors, Cytoplasmic and Nuclear; Shock, Septic; Soluble Guanylyl Cyclase	2004
Nitric oxide inhibition in the treatment of septic shock. Critical care medicine, 1995, Volume: 23, Issue:10 Topics: Animals; Humans; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Shock, Septic	1995
Methylene blue: NO panacea. The Journal of pediatrics, 1996, Volume: 129, Issue:6 Topics: Administration, Inhalation; Animals; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Infant, Newborn; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Shock, Septic	1996

Trials

11 trial(s) available for methylene blue and Shock, Septic

Article	Year
Methylene blue versus vasopressin analog for refractory septic shock in the preterm neonate: A randomized controlled trial. Journal of neonatal-perinatal medicine, 2022, Volume: 15, Issue:2 Topics: Hemodynamics; Humans; Infant; Infant, Newborn; Infant, Premature; Methylene Blue; Shock, Septic; Terlipressin; Vasoconstrictor Agents; Vasopressins	2022
Effect of methylene blue on hemodynamic and metabolic response in septic shock patients. Medicine, 2022, Jan-21, Volume: 101, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Hemodynamics; Humans; Hypotension; Methylene Blue; Middle Aged; Norepinephrine; Randomized Controlled Trials as Topic; Shock, Septic; Vasoconstrictor Agents; Young Adult	2022
Early adjunctive methylene blue in patients with septic shock: a randomized controlled trial. Critical care (London, England), 2023, 03-13, Volume: 27, Issue:1 Topics: Humans; Methylene Blue; Sepsis; Shock, Septic; Vasoconstrictor Agents	2023
A dose-finding study of methylene blue to inhibit nitric oxide actions in the hemodynamics of human septic shock. Nitric oxide : biology and chemistry, 2010, May-15, Volume: 22, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Free Radical Scavengers; Hemodynamics; Humans; Male; Methylene Blue; Middle Aged; Nitric Oxide; Shock, Septic; Vascular Resistance	2010
Does methylene blue administration to septic shock patients affect vascular permeability and blood volume? Critical care medicine, 2002, Volume: 30, Issue:10 Topics: Adult; Aged; Blood Volume; Capillary Permeability; Cardiotonic Agents; Enzyme Inhibitors; Female; Guanylate Cyclase; Hemodynamics; Humans; Indocyanine Green; Infusions, Intravenous; Lactic Acid; Male; Methylene Blue; Middle Aged; Prospective Studies; Pulmonary Circulation; Shock, Septic; Thermodilution; Vasoconstrictor Agents	2002
Methylene blue administration in septic shock: a clinical trial. Critical care medicine, 1995, Volume: 23, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Amino Acid Oxidoreductases; Blood Pressure; Cardiac Output; Female; Guanylate Cyclase; Humans; Lactates; Lactic Acid; Male; Methylene Blue; Middle Aged; Nitric Oxide Synthase; Oxygen; Prospective Studies; Shock, Septic	1995
Methylene blue increases myocardial function in septic shock. Critical care medicine, 1995, Volume: 23, Issue:8 Topics: Aged; Blood Gas Analysis; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Methylene Blue; Middle Aged; Myocardial Contraction; Nitric Oxide; Oxygen Consumption; Resuscitation; Shock, Septic	1995
Short-term effects of methylene blue on hemodynamics and gas exchange in humans with septic shock. Intensive care medicine, 1995, Volume: 21, Issue:12 Topics: Adult; Arginine; Endothelium, Vascular; Female; Hemodynamics; Humans; Male; Matched-Pair Analysis; Methylene Blue; Nitric Oxide; Prospective Studies; Pulmonary Gas Exchange; Shock, Septic; Single-Blind Method; Time Factors; Vasodilation	1995
Use of methylene blue in patients with refractory septic shock: impact on hemodynamics and gas exchange. Journal of critical care, 1998, Volume: 13, Issue:4 Topics: Adult; Aged; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Methylene Blue; Middle Aged; Nitric Oxide; Prospective Studies; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Shock, Septic; Time Factors	1998
Blockade of the action of nitric oxide in human septic shock increases systemic vascular resistance and has detrimental effects on pulmonary function after a short infusion of methylene blue. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1999, Volume: 32, Issue:12 Topics: Adult; Analysis of Variance; Blood Pressure; Enzyme Inhibitors; Female; Humans; Lung; Male; Methylene Blue; Middle Aged; Nitric Oxide; Pilot Projects; Pregnancy; Prospective Studies; Respiratory Insufficiency; Shock, Septic; Vascular Resistance	1999
Infusion of methylene blue in human septic shock: a pilot, randomized, controlled study. Critical care medicine, 2001, Volume: 29, Issue:10 Topics: Adult; Aged; Blood Chemical Analysis; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hemodynamics; Hospitals, University; Humans; Infusions, Intravenous; Intensive Care Units; Male; Methylene Blue; Middle Aged; Pilot Projects; Probability; Prospective Studies; Reference Values; Respiratory Function Tests; Severity of Illness Index; Shock, Septic; Survival Rate; Treatment Outcome	2001

Other Studies

42 other study(ies) available for methylene blue and Shock, Septic

Article	Year
Methylene blue for the treatment of refractory septic shock secondary to listeriosis in a paediatric patient. BMJ case reports, 2022, Feb-28, Volume: 15, Issue:2 Topics: Child; Child, Preschool; Extracorporeal Membrane Oxygenation; Female; Humans; Listeriosis; Methylene Blue; Shock, Septic; Vasoconstrictor Agents	2022
Methylene Blue to Neonatal Septic Shock treatment in neonate pigs Clinics (Sao Paulo, Brazil), 2022, Volume: 77 Topics: Animals; Disease Models, Animal; Lactic Acid; Male; Methylene Blue; Neonatal Sepsis; Sepsis; Shock, Septic; Swine	2022
Effect of methylene blue on hemodynamic response in the early phase of septic shock: A case series. Medicine, 2023, Jan-27, Volume: 102, Issue:4 Topics: Blood Pressure; Hemodynamics; Humans; Lactates; Methylene Blue; Norepinephrine; Shock, Septic; Vasoconstrictor Agents	2023
Methylene blue as adjunctive therapy in septic shock: correct drug diluent derives optimal efficacy. Critical care (London, England), 2023, 08-29, Volume: 27, Issue:1 Topics: Dental Care; Humans; Methylene Blue; Patients; Shock, Septic	2023
Drug diluent and efficacy of methylene blue in septic shock: authors' reply. Critical care (London, England), 2023, 09-05, Volume: 27, Issue:1 Topics: Humans; Methylene Blue; Patients; Shock, Septic	2023
Acute respiratory distress syndrome from Covid-19: A perfect storm from free radicals? Proposal for a new treatment. Medical hypotheses, 2020, Volume: 144 Topics: Animals; COVID-19; Diagnosis, Differential; Free Radicals; Humans; Inflammation; Methylene Blue; Models, Theoretical; Reactive Nitrogen Species; Reactive Oxygen Species; Respiratory Distress Syndrome; Shock, Septic; Vascular Resistance	2020
Unexplained Methemoglobinemia in Coronavirus Disease 2019: A Case Report. A&A practice, 2020, Volume: 14, Issue:9 Topics: Acute Kidney Injury; Aged; Antibodies, Monoclonal, Humanized; Antioxidants; Ascorbic Acid; Betacoronavirus; Coronavirus Infections; Corynebacterium; Corynebacterium Infections; COVID-19; Cytokine Release Syndrome; Enzyme Inhibitors; Erythrocyte Transfusion; Hematinics; Humans; Hydroxocobalamin; Hydroxychloroquine; Hypoxia; Male; Methemoglobinemia; Methylene Blue; Pandemics; Pneumonia, Bacterial; Pneumonia, Viral; Renal Replacement Therapy; Respiratory Insufficiency; SARS-CoV-2; Shock, Septic	2020
Greenish-blue discoloration of the brain and heart after treatment with methylene blue. Forensic science, medicine, and pathology, 2021, Volume: 17, Issue:1 Topics: Accidents, Traffic; Brain; Enzyme Inhibitors; Female; Heart; Humans; Methylene Blue; Middle Aged; Myocardium; Shock, Septic	2021
Methylene Blue Administration for Distributive Shock States in Critically Ill Children. The Israel Medical Association journal : IMAJ, 2020, Volume: 22, Issue:7 Topics: Blood Pressure; Child; Child, Preschool; Critical Illness; Fatal Outcome; Female; Humans; Infant; Infant, Newborn; Israel; Male; Methylene Blue; Retrospective Studies; Shock; Shock, Septic; Vasoplegia	2020
Index of suspicion. Pediatrics in review, 2014, Volume: 35, Issue:7 Topics: Anemia, Iron-Deficiency; Diagnosis, Differential; Diarrhea; Female; Fever of Unknown Origin; Humans; Infant; Infusions, Intravenous; Lymphohistiocytosis, Hemophagocytic; Male; Methemoglobinemia; Methylene Blue; Risk Assessment; Severity of Illness Index; Shock, Septic	2014
Impact of methylene blue in addition to norepinephrine on the intestinal microcirculation in experimental septic shock. Clinical hemorheology and microcirculation, 2014, Volume: 58, Issue:1 Topics: Animals; Cell Adhesion; Disease Models, Animal; Endothelium, Vascular; Endotoxins; Hemodynamics; Intestines; Leukocytes; Lipopolysaccharides; Methylene Blue; Microcirculation; Norepinephrine; Pressure; Rats; Rats, Inbred Lew; Shock, Septic	2014
A Novel Use of Methylene Blue in the Pediatric ICU. Pediatrics, 2015, Volume: 136, Issue:4 Topics: Combined Modality Therapy; Enzyme Inhibitors; Female; Humans; Hypotension; Infant; Methylene Blue; Shock, Septic; Vasoplegia	2015
In response to: "A systematic analysis of methylene blue for drug-induced shock". Clinical toxicology (Philadelphia, Pa.), 2017, Volume: 55, Issue:3 Topics: Humans; Methylene Blue; Shock; Shock, Septic	2017
A systematic analysis of methylene blue for drug-induced shock in humans. Clinical toxicology (Philadelphia, Pa.), 2017, Volume: 55, Issue:3 Topics: Humans; Methylene Blue; Shock; Shock, Septic	2017
Turquoise to dark green organs at autopsy. Virchows Archiv : an international journal of pathology, 2009, Volume: 454, Issue:3 Topics: Aged; Autopsy; Chromatography, High Pressure Liquid; Coronary Disease; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Humans; Hypertension; Male; Methylene Blue; Pancreatectomy; Pancreatic Neoplasms; Postoperative Complications; Shock, Septic; Sleep Apnea, Obstructive; Tissue Distribution	2009
Use of methylene blue for refractory septic shock during continuous venovenous hemodiafiltration. Pharmacotherapy, 2010, Volume: 30, Issue:3 Topics: Accidents, Traffic; Acute Kidney Injury; Blood Pressure; Catecholamines; Contraindications; Drug Resistance; Fatal Outcome; Hemodiafiltration; Humans; Male; Methylene Blue; Middle Aged; Nitric Oxide; Renal Replacement Therapy; Sepsis; Shock, Septic; Vasoconstrictor Agents	2010
The effects of methylene blue infusion on gastric tonometry and intestinal fatty acid binding protein levels in septic shock patients. Journal of critical care, 2010, Volume: 25, Issue:2 Topics: Aged; Aged, 80 and over; Enzyme Inhibitors; Fatty Acid-Binding Proteins; Female; Gastric Mucosa; Humans; Male; Manometry; Methylene Blue; Middle Aged; Prospective Studies; Shock, Septic; Treatment Outcome	2010
A fictive unit for the cardiac work for at least 83 years. Nitric oxide : biology and chemistry, 2010, Dec-15, Volume: 23, Issue:4 Topics: Hemodynamics; History, 20th Century; History, 21st Century; Humans; Methylene Blue; Nitric Oxide; Shock, Septic; Stroke Volume; Terminology as Topic; Ventricular Function	2010
Methylene blue as the future protecting agent for ischemic brain injury? Critical care medicine, 2010, Volume: 38, Issue:11 Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Heart Arrest; Humans; Methylene Blue; Neuroprotective Agents; Reperfusion Injury; Shock, Septic	2010
Prolonged methylene blue infusion in refractory septic shock: a case report. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2011, Volume: 58, Issue:4 Topics: Aged; Hemodynamics; Humans; Infusions, Intravenous; Male; Methylene Blue; Shock, Septic	2011
Local cutaneous necrosis secondary to a prolonged peripheral infusion of methylene blue in vasodilatory shock. The Annals of pharmacotherapy, 2012, Volume: 46, Issue:3 Topics: Female; Humans; Infusions, Intravenous; Ischemia; Methylene Blue; Middle Aged; Necrosis; Shock, Septic; Skin; Vasoconstriction	2012
Administration of methylene blue in human septic shock: renaissance of an old drug? Critical care medicine, 2003, Volume: 31, Issue:5 Topics: Blood Volume; Capillary Permeability; Guanylate Cyclase; Humans; Methylene Blue; Research Design; Risk Factors; Shock, Septic; Vasoconstrictor Agents	2003
Congenital methemoglobinemia: a rare cause of cyanosis in the newborn--a case report. Pediatrics, 2003, Volume: 112, Issue:2 Topics: Cyanosis; Cytochrome Reductases; Cytochrome-B(5) Reductase; Diagnosis, Differential; Female; Humans; Infant, Newborn; Male; Metabolism, Inborn Errors; Methemoglobin; Methemoglobinemia; Methylene Blue; Shock, Septic	2003
Methylene blue revisited: management of hypotension in a pediatric patient with bacterial endocarditis. The Journal of thoracic and cardiovascular surgery, 2005, Volume: 130, Issue:2 Topics: Cardiopulmonary Bypass; Cerebrovascular Disorders; Child; Endocarditis, Bacterial; Enzyme Inhibitors; Female; Heart Valve Prosthesis Implantation; Humans; Hypotension; Methylene Blue; Mitral Valve; Shock, Septic; Staphylococcal Infections; Vasoconstrictor Agents	2005
The effects of methylene blue on hemodynamic parameters and cytokine levels in refractory septic shock. The Korean journal of internal medicine, 2005, Volume: 20, Issue:2 Topics: Anti-Infective Agents, Urinary; Blood Pressure; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Humans; Infusions, Intravenous; Male; Methylene Blue; Middle Aged; Pulmonary Circulation; Retrospective Studies; Shock, Septic; Treatment Outcome; Vascular Resistance	2005
Methylene blue: an old-timer or a compound ready for revival? Critical care medicine, 2006, Volume: 34, Issue:11 Topics: Animals; Enzyme Inhibitors; Fluid Therapy; Heart Arrest; Humans; Inflammation; Methylene Blue; Reperfusion Injury; Shock, Septic	2006
Short-term beneficial effects of methylene blue on kidney damage in septic shock patients. Intensive care medicine, 2008, Volume: 34, Issue:2 Topics: Acute Kidney Injury; Aged; Analysis of Variance; Enzyme Inhibitors; Female; Glutathione Transferase; Humans; Male; Methylene Blue; Nitric Oxide Synthase; Prospective Studies; Shock, Septic; Treatment Outcome	2008
Effects of methylene blue on oxygen availability and regional blood flow during endotoxic shock. Critical care medicine, 1995, Volume: 23, Issue:10 Topics: Animals; Dogs; Escherichia coli Infections; Female; Guanylate Cyclase; Hemodynamics; Male; Methylene Blue; Oxygen Consumption; Random Allocation; Regional Blood Flow; Shock, Septic	1995
Methylene blue infusion in septic shock. Critical care medicine, 1995, Volume: 23, Issue:11 Topics: Coloring Agents; Humans; Methylene Blue; Nitric Oxide Synthase; Shock, Septic	1995
Methylene blue infusion in septic shock. Critical care medicine, 1995, Volume: 23, Issue:11 Topics: Animals; Coloring Agents; Guanylate Cyclase; Hemodynamics; Humans; Infusions, Intravenous; Methylene Blue; Shock, Septic	1995
Methylene blue reverses endotoxin-induced hypotension. Circulation research, 1994, Volume: 74, Issue:6 Topics: Animals; Blood Pressure; Cyclic GMP; Hypotension; Lipopolysaccharides; Methylene Blue; Nitric Oxide; Rabbits; Shock, Septic; Sulfhydryl Compounds	1994
Arteriolar endothelium-dependent vasodilation occurs during endotoxin shock. The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2 Topics: Acetylcholine; Animals; Arterioles; Endothelium, Vascular; Hemodynamics; Hydroquinones; Injections, Intra-Arterial; Injections, Intravenous; Male; Methylene Blue; Microcirculation; Nitric Oxide; Rats; Rats, Sprague-Dawley; Shock, Septic; Vasodilation	1993
Effects of methylene blue in septic shock. Critical care medicine, 1996, Volume: 24, Issue:6 Topics: Animals; Humans; Methylene Blue; Oxidation-Reduction; Rats; Shock, Septic	1996
Effect of methylene blue on refractory neonatal hypotension. The Journal of pediatrics, 1996, Volume: 129, Issue:6 Topics: Blood Pressure; Diseases in Twins; Drug Evaluation; Female; Heart Rate; Humans; Hypotension; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Male; Methylene Blue; Nitric Oxide; Shock, Septic	1996
Continuous infusion of methylene blue for septic shock. Postgraduate medical journal, 1996, Volume: 72, Issue:852 Topics: Antidotes; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Infusions, Intravenous; Male; Methylene Blue; Middle Aged; Shock, Septic	1996
[Inhibition of the nitric oxide pathway in refractory septic shock]. Revista medica de Chile, 1996, Volume: 124, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Dopamine; Female; Hemodynamics; Humans; Male; Methylene Blue; Middle Aged; Nitric Oxide; Norepinephrine; Prospective Studies; Shock, Septic	1996
Nitric oxide-independent activation of soluble guanylyl cyclase contributes to endotoxin shock in rats. The American journal of physiology, 1998, Volume: 275, Issue:4 Topics: Animals; Aorta; Blood Pressure; Charybdotoxin; Dexamethasone; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Guanidines; Guanylate Cyclase; Heart Rate; In Vitro Techniques; Lipopolysaccharides; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Inbred WKY; Shock, Septic; Tetraethylammonium	1998
Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility. The American journal of physiology, 1999, Volume: 276, Issue:1 Topics: Animals; Arginine; Blood Physiological Phenomena; Cyclic GMP; Drug Combinations; Enzyme Inhibitors; Humans; Interleukin-1; Methylene Blue; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nucleotides, Cyclic; omega-N-Methylarginine; Rats; Shock, Septic; Tumor Necrosis Factor-alpha	1999
Shortening of cardiac action potentials in endotoxic shock in guinea pigs is caused by an increase in nitric oxide activity and activation of the adenosine triphosphate-sensitive potassium channel. Critical care medicine, 2000, Volume: 28, Issue:6 Topics: Action Potentials; Adenosine Triphosphate; Animals; Cyclic GMP; Enzyme Inhibitors; Glyburide; Guanidines; Guinea Pigs; Lipopolysaccharides; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Papillary Muscles; Potassium Channels; Shock, Septic; Time Factors	2000
Continuously infused methylene blue modulates the early cardiopulmonary response to endotoxin in awake sheep. Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:10 Topics: Animals; Consciousness; Endotoxemia; Endotoxins; Enzyme Inhibitors; Hemodynamics; Infusions, Intravenous; Injections, Intravenous; Methylene Blue; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Sheep; Shock, Septic	2001
Methylene blue increases systemic vascular resistance in human septic shock. Preliminary observations. Intensive care medicine, 1992, Volume: 18, Issue:5 Topics: Adult; Aged; Combined Modality Therapy; Female; Hemodynamics; Humans; Methylene Blue; Norepinephrine; Respiration, Artificial; Shock, Septic; Vascular Resistance	1992
Anti-tumoral and anti-inflammatory effects of biological stains. Agents and actions, 1991, Volume: 34, Issue:3-4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Azure Stains; BCG Vaccine; Carrageenan; Female; Fibrosarcoma; Granuloma; Lipopolysaccharides; Male; Methylcholanthrene; Methylene Blue; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Shock, Septic; Tumor Necrosis Factor-alpha	1991