methylene blue has been researched along with Pain in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.11) | 18.7374 |
| 1990's | 10 (27.03) | 18.2507 |
| 2000's | 17 (45.95) | 29.6817 |
| 2010's | 3 (8.11) | 24.3611 |
| 2020's | 4 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z; Liu, Y; Lu, X; Ren, J; Sun, P | 1 |
| Burrows, CS; Duncan, JC; Martinez-Taboada, F | 1 |
| Bandeira, PN; Campos, AR; da Silva, AW; de Menezes, JESA; Dos Reis Lima, J; Dos Santos, HS; Evaristo, FFV; Ferreira, MKA; Holanda, CLA; Magalhães, FEA; Silva, FCO; Teixeira, EH | 1 |
| Han, HC; Lee, SW; Moon, SW; Park, JS; Suh, HR | 1 |
| Imam, MZ; Moniruzzaman, M | 1 |
| Anstey, A; Birchall, JC; Edwards, C; Haq, MI; John, DN; Kalavala, M; Morrissey, A; Smith, E | 1 |
| Akhtar, MN; Akira, A; Israf, DA; Khalid, MH; Khalivulla, SI; Lajis, N; Mohamad, AS; Ong, HM; Perimal, EK; Sulaiman, MR; Zareen, S | 1 |
| Akinci, SB; Aypar, Ü; Salman, AE; Salman, MA; Saricaoglu, F | 1 |
| Amarante, LH; Duarte, ID | 1 |
| Jain, NK; Kulkarni, SK; Patil, CS; Singh, A | 2 |
| IKEDA, S; KAWAMURA, T; NISHIYAMA, S; TAJIMA, K | 1 |
| Sadan, G; Tasatargil, A | 1 |
| Jain, NK; Kulkarni, SK; Patil, CS; Singh, VP | 1 |
| Desilva, GL; Desilva, SP; Grutter, PW; Meehan, RE | 1 |
| Aronov, S; Ben-Abraham, R; Givati-Divshi, D; Katz, Y | 2 |
| Kulkarni, SK; Padi, SV; Patil, CS; Singh, VP | 1 |
| Abdullah, FC; Balakhrisnan, G; Jais, AM; Jayaraman, KV; Somchit, MN; Sulaiman, MR; Zakaria, ZA | 1 |
| Hofmeister, EH; Kent, M; Read, MR | 1 |
| Abacioglu, N; Altug, S; Tunctan, B; Uludag, O; Zengil, H | 1 |
| Branco, LG; Nascimento, CG | 1 |
| Young, B | 1 |
| Hayaishi, O; Hyodo, M; Ito, S; Minami, T; Nishihara, I; Sakamoto, K | 1 |
| Eschalier, A; Fialip, J; Mestre, C; Pélissier, T; Wilcox, G | 1 |
| Chalfa, R; Elliott, CG; Mathewson, HS | 1 |
| Ferreira, SH; Lorenzetti, BB | 1 |
| Mashimo, T; Ohara, A; Shibuta, S; Yoshiya, I; Zhang, P | 1 |
| Holthusen, H | 1 |
| Inoue, T; Mashimo, T; Shibata, M; Shibuta, S; Yoshiya, I | 1 |
| Goto, K; Ishige, A; Kamei, J; Komatsu, Y; Suzuki, Y | 1 |
| Budziñski, M; Dorociak, A; Gumulka, W; Misterek, K | 1 |
| Douglass, HO; Lee, JS; Mendez, PA | 1 |
| Gebhart, GF; Maves, TJ; Meller, ST; Pechman, PS | 1 |
| Bhambure, ND; Bichile, LS; Gokhale, YA; Hase, NK; Jaindani, PG; Palekar, SN | 1 |
| Beaumont, AC; Collins, RE | 1 |
| Goldie, I; Wellisch, M | 1 |
1 review(s) available for methylene blue and Pain
| Article | Year |
|---|---|
Intraoperative detection of methemoglobinemia in a patient given benzocaine spray to relieve discomfort from a nasogastric tube: a case report.
Topics: Accidental Falls; Administration, Oral; Adult; Aerosols; Anesthetics, Local; Benzocaine; Blood Gas Analysis; Diagnosis, Differential; Guanylate Cyclase; Humans; Intraoperative Care; Intubation, Gastrointestinal; Male; Methemoglobin; Methemoglobinemia; Methylene Blue; Monitoring, Intraoperative; Nurse Anesthetists; Nursing Assessment; Oximetry; Pain; Risk Factors; Urinary Bladder | 2008 |
4 trial(s) available for methylene blue and Pain
| Article | Year |
|---|---|
Methylene Blue Combined with Ropivacaine for Intercostal Nerve Block After Autologous Costal Cartilage Removal in Juvenile Patients.
Topics: Adolescent; Child; Costal Cartilage; Humans; Intercostal Nerves; Methylene Blue; Pain; Ropivacaine | 2022 |
Clinical administration of microneedles: skin puncture, pain and sensation.
Topics: Enzyme Inhibitors; Female; Humans; Injections, Intradermal; Male; Methylene Blue; Microtechnology; Needles; Pain; Pilot Projects; Skin | 2009 |
Pain on injection of propofol: a comparison of methylene blue and lidocaine.
Topics: Adult; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Enzyme Inhibitors; Female; Hospitals, University; Humans; Lidocaine; Male; Methylene Blue; Middle Aged; Pain; Pain Measurement; Propofol; Prospective Studies; Severity of Illness Index | 2011 |
Involvement of the NO/cyclic GMP pathway in bradykinin-evoked pain from veins in humans.
Topics: Adult; Bradykinin; Cyclic GMP; Hand; Humans; Male; Methylene Blue; Nitric Oxide; Pain; Pain Measurement; Regional Blood Flow; Signal Transduction; Veins | 1997 |
32 other study(ies) available for methylene blue and Pain
| Article | Year |
|---|---|
Transversus abdominis plane block in rats: Preliminary cadaveric studies.
Topics: Abdominal Muscles; Abdominal Wall; Animals; Cadaver; Female; Humans; Infant; Methylene Blue; Pain; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Ultrasonography, Interventional | 2023 |
Antinociceptive activity of 3β-6β-16β-trihydroxylup-20 (29)-ene triterpene isolated from Combretum leprosum leaves in adult zebrafish (Danio rerio).
Topics: Acid Sensing Ion Channels; Amiloride; Analgesics; Animals; Camphor; Capsaicin; Combretum; Dose-Response Relationship, Drug; Female; Ketamine; Locomotion; Male; Methylene Blue; Naloxone; NG-Nitroarginine Methyl Ester; Nociception; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Receptors, N-Methyl-D-Aspartate; Ruthenium Red; Triterpenes; TRPV Cation Channels; Zebrafish; Zebrafish Proteins | 2020 |
Methylene blue induces an analgesic effect by significantly decreasing neural firing rates and improves pain behaviors in rats.
Topics: Action Potentials; Analgesics; Animals; Coloring Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Femoral Nerve; Hindlimb; Lidocaine; Male; Methylene Blue; Neural Inhibition; Neurons; Pain; Rats; Rats, Sprague-Dawley | 2021 |
Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica.
Topics: Acetic Acid; Anacardiaceae; Analgesics; Animals; Cyclic GMP; Ethanol; Female; Formaldehyde; Glutamic Acid; Glyburide; Hot Temperature; KATP Channels; Male; Methylene Blue; Mice; Pain; Phytotherapy; Plant Extracts; Plant Leaves; Solvents; Toxicity Tests, Acute | 2014 |
Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K(+) channels pathway in the systemic antinociception of flavokawin B.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Glyburide; Hypoglycemic Agents; Male; Methylene Blue; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase; Pain; Potassium Channels; Protein Kinase C; Signal Transduction | 2011 |
The kappa-opioid agonist (+/-)-bremazocine elicits peripheral antinociception by activation of the L-arginine/nitric oxide/cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Benzomorphans; Cyclic GMP; Guanylate Cyclase; Hyperalgesia; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pain; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Wistar; Receptors, Opioid, kappa | 2002 |
Sildenafil, a phosphodiesterase-5 inhibitor, enhances the antinociceptive effect of morphine.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Hyperalgesia; Male; Methylene Blue; Mice; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Sildenafil Citrate; Sulfones; Time Factors | 2003 |
THE HUMAN HAARSCHEIBE, ITS STRUCTURE AND FUNCTION.
Topics: Alkaline Phosphatase; Capillaries; Cholinesterases; Coloring Agents; Dihydroxyphenylalanine; Hair; Histocytochemistry; Histology; Humans; Methylene Blue; Nerve Tissue; Pain; Physiology; Staining and Labeling; Touch | 1964 |
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway.
Topics: Analgesics, Opioid; Animals; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Formaldehyde; Guanylate Cyclase; Male; Methylene Blue; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Pain; Pain Measurement; Rats; Rats, Wistar | 2004 |
Cholinergic-NO-cGMP mediation of sildenafil-induced antinociception.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetic Acid; Acetylcholine; Animals; Carrageenan; Cholinergic Agents; Cholinesterase Inhibitors; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Female; Guanylate Cyclase; Hyperalgesia; Male; Methylene Blue; Mice; Neostigmine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Sildenafil Citrate; Sulfones | 2004 |
The accuracy of distal posterior interosseous and anterior interosseous nerve injection.
Topics: Anesthetics, Local; Cadaver; Coloring Agents; Humans; Injections, Intralesional; Median Nerve; Methylene Blue; Nerve Block; Pain; Radial Nerve; Reproducibility of Results; Wrist | 2004 |
Involvement of nitric oxide in clonidine-induced spinal analgesia.
Topics: Acute Disease; Analgesia; Analgesics; Animals; Arginine; Clonidine; Injections, Spinal; Male; Methylene Blue; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Pain | 2005 |
Cerebroventricular injection of clonidine causes analgesia mediated by a nitrogen pathway.
Topics: Acute Disease; Analgesia; Analgesics; Animals; Arginine; Cerebral Ventricles; Clonidine; Injections; Male; Methylene Blue; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Pain; Random Allocation | 2005 |
Sildenafil induces hyperalgesia via activation of the NO-cGMP pathway in the rat neuropathic pain model.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Chronic Disease; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Injections, Spinal; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Pain Threshold; Piperazines; Purines; Rats; Rats, Wistar; Sciatic Neuropathy; Signal Transduction; Sildenafil Citrate; Sulfones | 2006 |
The antinociceptive activity of Muntingia calabura aqueous extract and the involvement of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in its observed activity in mice.
Topics: Acetic Acid; Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Elaeocarpaceae; Enzyme Inhibitors; Guanylate Cyclase; Male; Methylene Blue; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Signal Transduction | 2006 |
Paravertebral block for forelimb anesthesia in the dog--an anatomic study.
Topics: Anesthetics, Local; Animals; Brachial Plexus; Cadaver; Cervical Vertebrae; Dogs; Forelimb; Injections, Spinal; Methylene Blue; Nerve Block; Pain; Spinal Nerve Roots; Thoracic Vertebrae | 2007 |
Twenty-four-hour variation of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway demonstrated by the mouse visceral pain model.
Topics: Abdominal Pain; Analgesics; Animals; Arginine; Benzoquinones; Circadian Rhythm; Cyclic GMP; Enzyme Inhibitors; Male; Methylene Blue; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroprusside; Pain; Pain Measurement; Signal Transduction | 2007 |
Role of the spinal cord heme oxygenase-carbon monoxide-cGMP pathway in the nociceptive response of rats.
Topics: Animals; Carbon Monoxide; Cyclic GMP; Deuteroporphyrins; Heme; Heme Oxygenase (Decyclizing); Lysine; Male; Methylene Blue; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord | 2008 |
Nitric oxide mediates allodynia induced by intrathecal administration of prostaglandin E2 or prostaglandin F2 alpha in conscious mice.
Topics: Analysis of Variance; Animals; Arginine; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Injections, Spinal; Male; Methylene Blue; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1995 |
A method to perform direct transcutaneous intrathecal injection in rats.
Topics: Administration, Cutaneous; Animals; Injections, Spinal; Male; Methylene Blue; Morphine; Naloxone; Pain; Rats; Rats, Sprague-Dawley | 1994 |
Drug-induced methemoglobinemia in a healthy 20-year-old soldier undergoing shoulder surgery.
Topics: Adult; Arthroscopy; Fentanyl; Humans; Male; Methemoglobinemia; Methylene Blue; Midazolam; Pain; Propofol; Shoulder | 1993 |
Activation of the arginine-nitric oxide pathway in primary sensory neurons contributes to dipyrone-induced spinal and peripheral analgesia.
Topics: Analysis of Variance; Anesthesia, Spinal; Animals; Anti-Infective Agents, Urinary; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Dinoprostone; Dipyrone; Enzyme Inhibitors; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Methylene Blue; Neurons, Afferent; Nitric Oxide; omega-N-Methylarginine; Pain; Rats; Rats, Wistar | 1996 |
A new nitric oxide donor, NOC-18, exhibits a nociceptive effect in the rat formalin model.
Topics: Animals; Antidotes; Behavior, Animal; Formaldehyde; Injections, Intraventricular; Injections, Subcutaneous; Male; Methylene Blue; Motor Activity; Nitric Oxide; Nitroso Compounds; Nociceptors; Pain; Rats; Rats, Sprague-Dawley | 1996 |
Rapid development of nitric oxide-induced hyperalgesia depends on an alternate to the cGMP-mediated pathway in the rat neuropathic pain model.
Topics: Animals; Antidotes; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hemoglobins; Hot Temperature; Hyperalgesia; Ligation; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Pain; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord | 1998 |
Antinociceptive mechanism of Gosha-jinki-gan in streptozotocin-induced diabetic animals: role of nitric oxide in the periphery.
Topics: Analgesics; Animals; Arginine; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Enzyme Inhibitors; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Tail | 1999 |
Inhibition of inducible nitric oxide synthase in persistent pain.
Topics: Animals; Arginine; Carrageenan; Chronic Disease; Enzyme Inhibitors; Lysine; Male; Methylene Blue; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pain; Rats; Rats, Wistar | 2000 |
Unexpected cyanosis in the surgical patient.
Topics: Adult; Anesthetics, Local; Benzocaine; Cyanosis; Endoscopy; Female; Humans; Intubation, Gastrointestinal; Male; Methemoglobinemia; Methylene Blue; Middle Aged; Pain | 2000 |
Sildenafil-induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetic Acid; Analgesia; Animals; Arginine; Carrageenan; Central Nervous System; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Female; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Nociceptors; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones | 2001 |
Nitric oxide mediates the thermal hyperalgesia produced in a model of neuropathic pain in the rat.
Topics: Analysis of Variance; Animals; Arginine; Hot Temperature; Hyperalgesia; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1992 |
Boerhaaves' syndrome.
Topics: Esophageal Diseases; Fluoroscopy; Humans; Male; Methylene Blue; Middle Aged; Pain; Rupture, Spontaneous; Syndrome | 1991 |
The use of methylene blue in parathyroid surgery.
Topics: Humans; Intraoperative Period; Methylene Blue; Pain; Parathyroid Glands | 1989 |
The presence of nerves in original and regenerated synovial tissue in patients synovectomised for rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Biopsy; Humans; Knee; Knee Joint; Methods; Methylene Blue; Nerve Endings; Nerve Fibers, Myelinated; Nerve Regeneration; Pain; Staining and Labeling; Synovectomy; Synovial Membrane | 1969 |