methylene blue has been researched along with Muscle Relaxation in 203 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (20.20) | 18.7374 |
| 1990's | 150 (73.89) | 18.2507 |
| 2000's | 12 (5.91) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S; Kaye, AD; Liu, L; Lu, SY; Mei, Q; Niu, X; Pei, J; Wei, J; Xing, B; Xiong, L; Zhu, M; Zhu, X | 1 |
| Chen, YY; Fang, XD; Shen, YL; Wang, LL; Yang, F; Zhu, L | 1 |
| Ayajiki, K; Noda, K; Okamura, T; Toda, N | 1 |
| Kanda, M; Kurahashi, K; Nakamura, S; Shirahase, H; Tarumi, T | 1 |
| Jun, CH; Lee, TS; Sohn, UD | 1 |
| Bagcivan, I; Cetin, A; Cetin, M; Demirkoprulu, N; Karadas, B; Kaya, T; Soydan, AS | 1 |
| Feitosa, RL; Lemos, MC; Matsuda, NM | 1 |
| Barry, BK; Gruetter, CA; Ignarro, LJ; Kadowitz, PJ; McNamara, DB | 1 |
| Gruetter, CA; Ignarro, LJ; Kadowitz, PJ | 1 |
| DiSalvo, J; Galvas, PE | 1 |
| Furchgott, RF | 1 |
| Cherry, PD; Furchgott, RF; Jothianandan, D; Zawadzki, JV | 1 |
| Gruetter, CA; Gruetter, DY; Ignarro, LJ; Kadowitz, PJ; Lyon, JE | 1 |
| Burkman, AM; Fertel, RH; Keith, RA; Sokoloski, TD | 2 |
| Holzmann, S; Kukovetz, WR; Pöch, G | 1 |
| Holzmann, S | 1 |
| Fujii, K; Fujiwara, M; Muramatsu, I; Sakakibara, Y | 1 |
| Grbović, L; Jovanović, A; Jovanović, S | 1 |
| Shikada, K; Tanaka, S | 1 |
| Carretero, OA; Rhaleb, NE | 1 |
| Matsumoto, M; Miyamoto, A; Nishio, A | 1 |
| Chen, SJ; Wu, CC; Yen, MH | 5 |
| Johnson, DE; Kannan, MS | 1 |
| Aliev, G; Caparrotta, L; Chinellato, A; Fassina, G; Froldi, G; Pandolfo, L; Prosdocimi, M; Ragazzi, E | 1 |
| Costa, G; García-Pascual, A; Jimenez, E; Labadía, A | 1 |
| Kuo, SC; Yu, SM | 1 |
| Mizuno, R; Ohhashi, T | 1 |
| Garfield, RE; Izumi, H | 1 |
| Ribeiro, JM; Valenzuela, JG; Walker, FA | 1 |
| Barnes, PJ; Lei, YH; Rogers, DF | 1 |
| Brunner, F; Mayer, B; Schmidt, K | 1 |
| Gryglewski, RJ; Hatchett, RJ; Jakubowski, AM; Zembowicz, A | 1 |
| Inoue, R; Ito, Y; Jing, L; Takahashi, S; Tashiro, K | 1 |
| Asano, M; Imaizumi, Y; Matsuda, T; Watanabe, M; Yokota, Y | 1 |
| Akaike, T; Ishizaka, H; Maeda, H; Matsunaga, T; Okumura, K; Sato, K; Tabuchi, T; Tsunoda, R; Yasue, H | 1 |
| Bozinovski, J; Brien, JF; Marks, GS; Nakatsu, K | 1 |
| Chang, KC; Chung, BH | 1 |
| Bynoe, TC; Hirshman, CA; Lindeman, KS; Stuart-Smith, K | 1 |
| Imai, S; Ishibashi, T; Kato, K; Kawada, T; Sasage, H | 1 |
| Oztürk, Y | 1 |
| Baker, RA; Brookes, SJ; Saccone, GT; Toouli, J | 1 |
| Hsu, GL; Lue, TF; Martinez-Piñeiro, L; Tanagho, EA; Trigo-Rocha, F; von Heyden, B | 1 |
| Andersson, KE; Persson, K | 1 |
| Satake, N; Shibata, S; Zhou, Q | 1 |
| De Kimpe, SJ; Nijkamp, FP; Tielemans, W; Van Heuven-Nolsen, D | 1 |
| Duckles, SP; Li, YJ | 1 |
| Calixto, JB; Schlemper, V | 1 |
| Grbović, L; Jovanović, A; Tulić, I | 1 |
| Kaiser, L; Lamb, VL; Mupanomunda, M; Schwartz, AJ; Schwartz, NR; Tithof, PK; Williams, JF | 1 |
| Coleman, HA; Parkington, HC; Tare, M; Tonta, MA | 1 |
| Chen, CF; Chiou, WF; Chou, CJ; Liao, JF; Sham, AY | 1 |
| Pickard, RS; Powell, PH; Zar, MA | 2 |
| Balcioglu, A; Uma, S | 1 |
| Helsen, LF; Meulemans, AL; Schuurkes, JA | 1 |
| Fukata, Y; Fukushima, H; Harada, K; Kasai, H; Ogawa, N | 1 |
| Battistini, B; Filep, JG; Sirois, P | 1 |
| Fukata, Y; Fukushima, H; Jinno, Y; Kaneta, S; Ogawa, N; Okada, Y; Yokoyama, T | 1 |
| Hashimoto, M; Ishida, Y; Masumura, S; Sakuma, I; Tanaka, Y | 1 |
| Aikawa, J; Akatsuka, N; Fukazawa, M; Hara, K; Ishikawa, M; Moroi, M; Namiki, A; Yamaguchi, T | 1 |
| Bennett, WM; Holcomb, S; McCarron, DA; Roullet, JB; Xue, H | 1 |
| Fayngersh, RP; Hintze, TH; Kaminski, PM; Pritchard, KA; Wolin, MS; Wu, M | 1 |
| Jones, KA; Katusić, ZS; Lorenz, RR; Sieck, GC; Warner, DO | 1 |
| Li, CG; McLaren, A; Rand, MJ | 1 |
| Chen, X; Gillis, CN | 1 |
| Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S; Yamaguchi, M | 1 |
| Anderson, DE; Rosen, GM; Rubin, LJ; Tod, ML; Tseng, CM; Yuan, XJ | 1 |
| Kinoshita, M; Matsumoto, T; Okamura, T; Toda, N | 1 |
| Fukushima, S; Ohhashi, T | 1 |
| Gray, GA; Schott, CA; Stoclet, JC | 1 |
| Lin, JK; Lin-Shiau, SY; Wang, JM | 1 |
| Chang, KC; Chong, WS; Chun, GW; Lee, IJ; Park, BW; Park, PS; Seung, BW | 1 |
| Birmingham, AT; Hill, SJ; James, MJ | 1 |
| Dyer, DC; Fiscus, RR; Grujic, Z; Wang, X; Zhang, L | 1 |
| Chang, KS; Davis, RF; Zhong, MZ | 1 |
| Kotsanas, G; Raymond, GL; Wendt, IR | 1 |
| García-Sacristán, A; Prieto, D; Sánez de Tejada, I; Simonsen, U | 1 |
| Goto, Y; Muramatsu, I; Takakura, K | 1 |
| Daniel, EE; Kwan, CY; Zheng, XF | 1 |
| Dik, IE; Folkerts, G; Henricks, PA; Nijkamp, FP; Sadeghi-Hashjin, G; Van de Loo, PG; Van der Linde, HJ | 1 |
| Kamata, K; Kasuya, Y; Kohzuki, M | 1 |
| Coceani, F; Kelsey, L; Seidlitz, E | 1 |
| Ayajiki, K; Okamura, T; Toda, M; Toda, N | 1 |
| Kitada, Y | 1 |
| Davis, P; Gossell, M; Powell, N; Simon, OR | 1 |
| Breslin, E; Cawley, T; Docherty, JR; Geraghty, J; Osborne, H | 1 |
| Bharadwaj, LA; Prasad, K | 1 |
| Angus, JA; Fujiwara, T | 1 |
| Ayajiki, K; Kangawa, K; Okamura, T; Toda, N | 1 |
| Barahona, MV; García-Sacristán, A; Hernández, M; Jiménez-Cidre, M; Orensanz, LM; Prieto, D; Rivera, L; Simonsen, U | 1 |
| Andersson, KE; Ny, L; Persson, K; Werkström, V | 1 |
| Dodd-o, JM; Lakatta, EG; Silverman, HS; Zheng, G; Ziegelstein, RC | 1 |
| Cai, Y; Chen, Y; Luo, W | 1 |
| Kinoshita, M; Liu, Q; Matsumoto, T; Nakae, I; Omura, T; Takahashi, M; Takaoka, A | 1 |
| Mizuno, R; Ohhashi, T; Wang, H | 1 |
| Ishiguro, S; Matsuyama, T; Nishio, A; Sakaguchi, H | 1 |
| Adegunloye, BJ; Sofola, OA | 1 |
| Cheng, YW; Kang, JJ | 1 |
| Azuma, H; Goto, M; Ishida, A; Kamikawatoko, S; Masuda, H; Tamaoki, S; Tokoro, T | 1 |
| Agata, N; Shigenobu, K; Tanaka, H | 1 |
| Cordellini, S; Vassilieff, VS | 1 |
| Bagger, JP; Frøbert, O; Mikkelsen, EO; Tankó, LB | 1 |
| Azuma, H; Hamasaki, H; Ishida, A; Kamikawatoko, S; Masuda, H; Sato, J; Tokoro, T | 1 |
| Jones, KA; Stuart-Smith, K; Warner, DO | 1 |
| Bina, S; Hart, JL; Jing, M; Ling, GS; Muldoon, SM | 1 |
| Black, SM; Chen, YQ; Clyman, RI; Mauray, F; Riemer, RK; Waleh, N | 1 |
| Jones, KA; Pabelick, C; Perkins, WJ; Warner, DO | 1 |
| Marques, MJ; Meirelles, UM; Santo Neto, H | 1 |
| Fukami, Y; Ito, T; Matsui, H; Mukawa, H; Nakashima, Y; Numaguchi, Y; Okumura, K; Toki, Y | 1 |
| Masek, K; Růzicka, V; Sevcík, J; Slánský, J; Smejkal, J | 1 |
| Chen, ZY; Ho, WK; Huang, Y; Kwan, KY; Zhang, ZS; Zhu, M | 1 |
| Hwang, TL; Teng, CM; Wu, CC | 1 |
| Kawakami, N; Kitamura, K; Nishijima, H; Shimamura, K; Uchida, R | 1 |
| Sekiguchi, F; Shimamura, K; Sunano, S; Tanaka, S; Watanabe, H | 1 |
| Baskakov, MB; Kapilevich, LV; Kuskov, MV; Lapshina, IuM; Medvedev, MA | 1 |
| Ayhan, IH; Ergün, H; Tulunay, FC | 1 |
| Adeyemi, OO; Okpo, SO; Young-Nwafor, CC | 1 |
| Legzdins, P; Pang, CC; Poon, JS; Wang, YX | 1 |
| Eardley, I; Joyce, AD; Minhas, S; Morrison, JB | 1 |
| Chiu, JH; Jiang, JK; Lin, JK; Yu, IT | 1 |
| Angielski, S; Jankowski, M; Kalinowski, L; Szczepanska-Konkel, M | 1 |
| Ahn, HY; Fang, LH; Hong, JT; Kim, TJ; Kim, Y; Lee, CK; Park, YS; Yun, YP; Zhang, YH | 1 |
| Grser, T; Rubanyi, GM | 1 |
| Fujieda, N; Harada, T; Kawahara, T; Kudo, T; Nishizawa, O; Noto, H; Shimoda, N; Suzuki, K; Suzuki, T; Tsuchida, S | 1 |
| Aronson, WJ; Bush, PA; Dorey, FJ; Ignarro, LJ; Rajfer, J | 1 |
| Braida, C; Holzmann, S; Kukovetz, WR; Pöch, G | 2 |
| Bradley, ME; Buxton, IL; Dalziel, HH; Keef, K; Sanders, KM; Ward, SM; Westfall, DP | 1 |
| Barnes, PJ; Crawley, DE; Evans, TW; Liu, SF; Rohde, JA | 1 |
| Hisayama, T; Moritoki, H; Takeuchi, S; Yoshikawa, T | 1 |
| Conklin, JL; Du, C; Ledlow, A; Manternach, PL; Murray, JA | 1 |
| Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S | 1 |
| Gray, DW; Marshall, I | 1 |
| Ahmedzadeh, N; Daniel, EE; Jury, J | 1 |
| Endo, Y; Hattori, Y; Kanno, M; Nagashima, M | 1 |
| Hattori, K; Kobayashi, Y; Nakase, A; Shimoura, K; Yamauchi, M | 1 |
| Julou-Schaeffer, G; Schneider, F; Schott, C; Stoclet, JC | 1 |
| Chang, KC; Lim, JK; Park, CW | 1 |
| Oe, H; Satake, N; Sawada, T; Shibata, S | 1 |
| Hisayama, T; Moritoki, H; Takeuchi, S; Ueda, H; Yamamoto, T | 1 |
| Biondi, ML; Feletou, M; Peglion, JL; Vanhoutte, PM; Vilaine, JP; Villeneuve, N | 1 |
| Ali, S; Fiscus, RR; Han, C; Joyce, CD; Murad, F; Wang, X; Zhou, HL | 1 |
| Chen, CF; Chiou, WF; Yen, MH | 1 |
| Oe, H; Satake, N; Shibata, S | 1 |
| Desai, KM; Sessa, WC; Vane, JR | 1 |
| Torphy, TJ; Zhou, HL | 1 |
| Satoh, K; Taira, N; Yamada, H; Yoneyama, F | 1 |
| Borg, C; Cavero, I; Mestre, M; Mondot, S | 1 |
| Desai, KM; Sessa, WC; Vane, JR; Zembowicz, A | 1 |
| Castillo, C; Hong, E; Valencia, I | 1 |
| Benedito, S; Nyborg, NC; Prieto, D | 1 |
| Dembinska-Kiec, A; Pallapies, D; Peskar, BA; Peskar, BM; Simmet, T | 1 |
| Andersson, KE; Forman, A; Garcia Pascual, A; Persson, K; Tøttrup, A | 1 |
| Cohen, RA; Cowan, CL | 1 |
| Aloamaka, CP; Bopelet, M; Ebeigbe, AB; Kamanyi, A; Obiefuna, PC | 1 |
| Collins, P; Jiang, CW; Lindsay, DC; Poole-Wilson, PA; Sarrel, PM | 1 |
| Beckmann, R; Goessl, C; Knispel, HH | 1 |
| Gräser, T; Li, DS; Vedernikov, YP | 1 |
| Aikawa, J; Akatsuka, N | 1 |
| Ohhashi, T; Takahashi, N | 1 |
| Berkenboom, G; Fang, ZY; Fontaine, J; Goldman, M; Unger, P | 1 |
| Dóra, E; Faragó, M; Horváth, I; Kovách, AG; Szabó, C | 1 |
| Flavahan, NA; Vanhoutte, PM | 1 |
| Barnes, PJ; Rhoden, KJ | 1 |
| Homma, Y; Kawakami, Y; Masaki, Y; Munakata, M; Otsuka, Y; Sakuma, I; Ukita, H | 1 |
| Douglas, SA; Hiley, CR | 1 |
| Akatsuka, N; Namiki, A | 1 |
| Fernandes, LB; Goldie, RG | 1 |
| Allen, SL; Foster, RW; Morgan, GP; Small, RC | 1 |
| Lefer, AM; Lefer, DJ | 1 |
| Kaiser, L; Sparks, HV; Spickard, RC; Williams, JF | 1 |
| Drummer, OH; Henry, PJ; Horowitz, JD | 1 |
| Klaas, M; Wadsworth, R | 1 |
| Fujiwara, T; Itoh, T; Kuriyama, H; Nishiye, E; Satoh, S; Sumimoto, K; Suzuki, H | 1 |
| Eltze, M | 1 |
| Barnette, M; Fine, C; Grous, M; Ormsbee, HS; Torphy, TJ | 1 |
| Aquino, S; Copello, J; Müller, A; Villamil, MF | 1 |
| Flavahan, NA; Shimokawa, H; Vanhoutte, PM | 1 |
| Chen, G; Suzuki, H | 1 |
| Ramwell, PW; Thomas, G | 1 |
| Kikkawa, K; Murata, S; Nagao, T | 1 |
| Buga, GM; Byrns, RE; Ignarro, LJ; Wood, KS | 1 |
| Mostaghim, R; Ramwell, PW; Thomas, G | 1 |
| Bowman, A; Gillespie, JS; Soares-da-Silva, P | 1 |
| Kukovetz, WR; Schmidt, K | 1 |
| Karaki, H; Nagase, H; Urakawa, N | 1 |
| Lefer, AM; Yanagisawa, A | 1 |
| Bråtveit, M; Helle, KB; Rydningen, HT | 1 |
| Ignarro, LJ; Kadowitz, PJ | 1 |
| Murad, F; Rapoport, RM; Schwartz, K; Waldman, SA; Winquist, RJ | 1 |
| Matsuoka, I; Nakanishi, H; Sakurai, K | 1 |
| Holzmann, S; Kukovetz, WR | 1 |
| Cline, WH; Kolm, P; Lee, TJ; Nickols, GA; Shirasaki, Y; Su, C | 1 |
| Alves, C; Bing, RJ; Menon, NK; Saeed, M; Saito, T; Wolf, A | 1 |
| Dusting, GJ; Read, MA; Stewart, AG | 1 |
| Alaranta, S; Klinge, E; Sjöstrand, NO | 1 |
| Bing, RJ; Saeed, M | 1 |
| Toda, N | 1 |
3 review(s) available for methylene blue and Muscle Relaxation
| Article | Year |
|---|---|
The role of endothelium in the responses of vascular smooth muscle to drugs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Catechols; Endothelium; Histamine; Hydroquinones; Hypoxia; Masoprocol; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandins; Quinacrine; Serotonin; Substance P; Thrombin | 1984 |
Endothelial cells as mediators of vasodilation of arteries.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Calcimycin; Cyclic GMP; Endothelium; Fatty Acids; Hemoglobins; Humans; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Vasodilation | 1984 |
The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Cyclic GMP; Drug Tolerance; Humans; In Vitro Techniques; Mercaptoethanol; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroso Compounds; Prostaglandins; S-Nitrosothiols; Vasodilation | 1985 |
200 other study(ies) available for methylene blue and Muscle Relaxation
| Article | Year |
|---|---|
Inhibition of cardiomyocyte contractile/relaxation by MN9202 and mechanisms involved.
Topics: Animals; Calcium; Cell Shape; Colforsin; Dihydropyridines; Methylene Blue; Muscle Contraction; Muscle Relaxation; Myocytes, Cardiac; Nitrobenzenes; Rats; Tetraethylammonium | 2008 |
Curcumin ameliorates high glucose-induced acute vascular endothelial dysfunction in rat thoracic aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Cardiotonic Agents; Curcumin; Endothelium, Vascular; Glucose; Guanylate Cyclase; Heme Oxygenase-1; Male; Methylene Blue; Muscle Relaxation; Protoporphyrins; Rats; Rats, Sprague-Dawley; Vasodilation | 2009 |
Functional study on nitroxidergic nerve in isolated dog pulmonary arteries and veins.
Topics: Animals; Dogs; Hexamethonium; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Nicotine; Nitroarginine; Nitrogen Oxides; Pulmonary Artery; Pulmonary Veins | 2002 |
Role of intracellular Ca2+ in endothelium-dependent contraction and relaxation of rabbit intrapulmonary arteries.
Topics: Animals; Aspirin; Calcimycin; Calcium; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Ionomycin; Ionophores; Male; Methacrylates; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Pulmonary Artery; Quinacrine; Rabbits; Terpenes; Thapsigargin | 2003 |
NO/cyclic GMP pathway mediates the relaxation of feline lower oesophageal sphincter.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Esophagogastric Junction; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxadiazoles; Quinoxalines; Signal Transduction; Vasoactive Intestinal Peptide | 2003 |
Comparative relaxant effects of YC-1 and DETA/NO on spontaneous contractions and the levels of cGMP of isolated pregnant rat myometrium.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indazoles; Male; Methylene Blue; Muscle Relaxation; Myometrium; Nitric Oxide Donors; Pregnancy; Rats; Rats, Wistar; Time Factors; Triazenes; Uterine Contraction | 2005 |
The effect of guanylate cyclase inhibitors on non-adrenergic and non-cholinergic neurogenic relaxations of the South American opossum lower esophageal sphincter.
Topics: Aminoquinolines; Animals; Cyclic GMP; Cysteamine; Electric Stimulation; Esophageal Sphincter, Lower; Female; Guanylate Cyclase; Hydrazines; Hydroxylamine; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Opossums; Oxadiazoles; Penicillamine; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase | 2008 |
Coronary arterial relaxation and guanylate cyclase activation by cigarette smoke, N'-nitrosonornicotine and nitric oxide.
Topics: Animals; Arteries; Blood Proteins; Cattle; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Activation; Ferrocyanides; Guanylate Cyclase; Heme; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nicotine; Nitric Oxide; Nitrosamines; Smoking | 1980 |
Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite.
Topics: Amyl Nitrite; Animals; Cattle; Coronary Vessels; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Sodium Nitrite | 1981 |
Concentration and time-dependent relationships between isosorbide dinitrate-induced relaxation and formation of cyclic GMP in coronary arterial smooth muscle.
Topics: Animals; Cattle; Cyclic GMP; Guanylate Cyclase; Isosorbide Dinitrate; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular | 1983 |
Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; In Vitro Techniques; Methemoglobin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Sodium Nitrite; Vasodilator Agents | 1981 |
Vascular tolerance to nitroglycerin and cyclic GMP generation in rat aortic smooth muscle.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Drug Tolerance; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Function of cyclic GMP in acetylcholine-induced contraction of coronary smooth muscle.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Animals; Cattle; Coronary Vessels; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular | 1982 |
Nitroglycerin tolerance and cyclic GMP generation in the longitudinal smooth muscle of the guinea-pig ileum.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guinea Pigs; Ileum; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroglycerin; Nitroprusside; Time Factors | 1983 |
Endothelium-induced relaxation by acetylcholine associated with larger rises in cyclic GMP in coronary arterial strips.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetylcholine; Animals; Cattle; Coronary Vessels; Cyclic GMP; Endothelium; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular | 1982 |
Vasorelaxing actions of molsidomine and its metabolites, in comparison with nitroglycerin.
Topics: Animals; Calcium; Dogs; Female; Male; Methemoglobin; Methylene Blue; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Oxadiazoles; Potassium Chloride; Sydnones; Vasodilator Agents | 1983 |
K+ channel blockers do not modify relaxation of guinea-pig uterine artery evoked by acetylcholine.
Topics: Acetylcholine; Animals; Arginine; Arteries; Diethylcarbamazine; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Isotonic Solutions; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Potassium Channels; Uterus | 1995 |
K+ channel openers produce epithelium-dependent relaxation of the guinea-pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Benzopyrans; Cromakalim; Epithelium; Guinea Pigs; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Piperidines; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Thromboxane A2; Trachea; Vasoactive Intestinal Peptide | 1995 |
Role of B1 and B2 receptors and of nitric oxide in bradykinin-induced relaxation and contraction of isolated rat duodenum.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bradykinin; Duodenum; Guanylate Cyclase; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, Bradykinin | 1994 |
Endothelial modulation of vascular tone in isolated porcine and bovine basilar arteries.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Basilar Artery; Bradykinin; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Orchiectomy; Sodium Fluoride; Swine | 1994 |
Alterations of ex vivo vascular reactivity in intraperitoneal sepsis.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Temperature; Cecum; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Sepsis; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1994 |
Modulation of nitric oxide-dependent relaxation of pig tracheal smooth muscle by inhibitors of guanylyl cyclase and calcium activated potassium channels.
Topics: Aminoquinolines; Animals; Calcium; Charybdotoxin; Electric Stimulation; Guanylate Cyclase; Isoproterenol; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroprusside; Penicillamine; Peptides; Potassium Channels; S-Nitroso-N-Acetylpenicillamine; Scorpion Venoms; Swine; Trachea | 1995 |
Endothelial nucleotide-mediated aorta relaxation in aged Watanabe heritable hyperlipidemic rabbits.
Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Aorta, Thoracic; Arginine; Arteriosclerosis; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Hyperlipidemia, Familial Combined; Male; Methylene Blue; Microscopy, Electron; Microscopy, Electron, Scanning; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinergic Antagonists; Rabbits; Receptors, Muscarinic; Receptors, Purinergic; Suramin; Uridine Triphosphate | 1995 |
Endothelium-dependent relaxation to acetylcholine in bovine oviductal arteries: mediation by nitric oxide and changes in apamin-sensitive K+ conductance.
Topics: Acetylcholine; Animals; Apamin; Arginine; Arteries; Cattle; Cyclic GMP; Cysteine; Endothelium, Vascular; Enzyme Inhibitors; Fallopian Tubes; Female; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Ouabain; Potassium; Potassium Channel Blockers; S-Nitrosothiols | 1995 |
Vasorelaxant effect of isoliquiritigenin, a novel soluble guanylate cyclase activator, in rat aorta.
Topics: Aldehyde Reductase; Animals; Aorta; Chalcone; Chalcones; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Guanylate Cyclase; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Platelet Aggregation Inhibitors; Pyrrolidinones; Quinolones; Rats; Rats, Wistar; Rolipram | 1995 |
5-Hydroxytryptamine-induced NO-dependent relaxation in isolated strips of monkey popliteal lymph nodes.
Topics: Animals; Arginine; Aspirin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Ketanserin; Lymph Nodes; Macaca; Male; Methiothepin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Serotonin; Serotonin Receptor Agonists | 1995 |
Relaxant effects of nitric oxide and cyclic GMP on pregnant rat uterine longitudinal smooth muscle.
Topics: Animals; Calcium; Carbachol; Cyclic GMP; Female; Guanosine 5'-O-(3-Thiotriphosphate); Methylene Blue; Muscle Relaxation; Myometrium; Nitric Oxide; Nitroprusside; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Uterine Contraction | 1995 |
A salivary nitrophorin (nitric-oxide-carrying hemoprotein) in the bedbug Cimex lectularius.
Topics: Animals; Aorta; Bedbugs; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Hemeproteins; Hydrogen-Ion Concentration; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Rabbits; Salivary Glands; Salivary Proteins and Peptides; Superoxide Dismutase; Vasodilation | 1995 |
Regulation of NANC neural bronchoconstriction in vivo in the guinea-pig: involvement of nitric oxide, vasoactive intestinal peptide and soluble guanylyl cyclase.
Topics: Airway Resistance; Amino Acid Oxidoreductases; Animals; Arginine; Autonomic Nervous System; Blood Pressure; Bronchoconstriction; Capsaicin; Chymotrypsin; Electric Stimulation; Guanylate Cyclase; Guinea Pigs; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Vagus Nerve; Vasoactive Intestinal Peptide | 1993 |
Inhibition of nitric oxide synthesis by methylene blue.
Topics: Amino Acid Oxidoreductases; Animals; Calcimycin; Cattle; Cells, Cultured; Cyclic GMP; Cytochrome c Group; Endothelium, Vascular; Guanylate Cyclase; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Swine | 1993 |
Involvement of nitric oxide in the endothelium-dependent relaxation induced by hydrogen peroxide in the rabbit aorta.
Topics: Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascular; Female; Hydrogen Peroxide; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits | 1993 |
Role of nitric oxide in non-adrenergic, non-cholinergic relaxation and modulation of excitatory neuroeffector transmission in the cat airway.
Topics: Animals; Arginine; Atropine; Autonomic Nervous System; Cats; Cysteine; Electric Stimulation; Guanethidine; Membrane Potentials; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Oxyhemoglobins; S-Nitrosothiols; Serotonin; Synaptic Transmission; Trachea; Vasoactive Intestinal Peptide | 1995 |
Endothelium-derived relaxing factor released by 5-HT: distinct from nitric oxide in basilar arteries of normotensive and hypertensive rats.
Topics: Animals; Arginine; Basilar Artery; Cerebrovascular Circulation; Endothelium, Vascular; Hypertension; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin | 1994 |
Vasodilator effect of carboxy-2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl in the coronary circulation: in vivo and in vitro studies.
Topics: Animals; Arginine; Benzoates; Blood Pressure; Coronary Circulation; Cyclic N-Oxides; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Female; Free Radicals; Guanylate Cyclase; Heart Rate; Imidazoles; In Vitro Techniques; Infusions, Intra-Arterial; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrogen Dioxide; Theophylline; Vasodilator Agents | 1994 |
Inhibition of nitrovasodilators by pyocyanin and methylene blue is dissociated from nitric oxide formation.
Topics: Animals; In Vitro Techniques; Luminescent Measurements; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Phenethylamines; Psychotropic Drugs; Pyocyanine; Rabbits; Vasodilator Agents | 1994 |
Photo-induced adequate nitric oxide (PIANO)-mediated relaxation in isolated rabbit corpus cavernosum.
Topics: Animals; Arginine; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Penis; Photolysis; Rabbits; Streptozocin; Ultraviolet Rays | 1994 |
Differential effects of nitrovasodilators and nitric oxide on porcine tracheal and bronchial muscle in vitro.
Topics: Animals; Bronchi; Bronchoconstriction; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroprusside; Swine; Trachea; Vasodilator Agents | 1994 |
Modification by LY 83583 and methylene blue of relaxation induced by nitric oxide, glyceryl trinitrate, sodium nitroprusside and atriopeptin in aortae of the rat, guinea-pig and rabbit.
Topics: Aminoquinolines; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cyclic GMP; Drug Interactions; Enzyme Activation; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Nitroprusside; Rabbits; Rats; Rats, Wistar; Vasodilator Agents | 1994 |
Effects of the agents affecting cyclic nucleotide metabolism on the bradykinin- and des-Arg9-bradykinin-induced relaxations and contractions in isolated rat duodenum.
Topics: Animals; Bradykinin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Duodenum; Imidazoles; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Niacin; Rats; Receptors, Bradykinin; Thromboxane-A Synthase | 1994 |
Nitric oxide mediates nonadrenergic, noncholinergic neural relaxation in the Australian possum.
Topics: Animals; Arginine; Electric Stimulation; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Opossums; Sphincter of Oddi | 1993 |
Cyclic guanosine monophosphate mediates penile erection in the rat.
Topics: Alprostadil; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Ethylmaleimide; Glutamates; Glutamic Acid; Male; Methylene Blue; Muscle Relaxation; N-Methylaspartate; Neurotransmitter Agents; Nitroprusside; Papaverine; Penile Erection; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide | 1993 |
Non-adrenergic, non-cholinergic relaxation and levels of cyclic nucleotides in rabbit lower urinary tract.
Topics: Animals; Arginine; Cyclic AMP; Cyclic GMP; Electric Stimulation; Female; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroarginine; Rabbits; Urethra | 1994 |
Inhibitory effect of sodium nitroprusside on the relaxing action of isoproterenol in isolated rat urinary bladder.
Topics: Animals; Cyclic GMP; Dobutamine; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Nitroprusside; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Urinary Bladder | 1994 |
Reversal of bradykinin-induced relaxation to contraction after interferon-gamma in bovine isolated mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amino Acid Sequence; Animals; Bradykinin; Cattle; Cycloheximide; In Vitro Techniques; Interferon-gamma; Mesenteric Arteries; Methylene Blue; Molecular Sequence Data; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Prostaglandin Endoperoxides, Synthetic; Receptors, Bradykinin; Thromboxane A2; Up-Regulation; Vasoconstrictor Agents | 1994 |
Mechanisms of relaxation by pyrogallol and methylthioninium chloride in perfused rat mesenteric artery.
Topics: Animals; Arginine; Capsaicin; Catalase; Deferoxamine; Dose-Response Relationship, Drug; Indomethacin; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Nitroarginine; Pyrogallol; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation | 1994 |
Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea-pig isolated trachea.
Topics: Animals; Arginine; Bradykinin; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Trachea | 1994 |
L-arginine induces relaxation of human uterine artery with both intact and denuded endothelium.
Topics: Arginine; Arteries; Calmodulin; Dexamethasone; Endothelium, Vascular; Female; Humans; Imidazoles; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Regional Blood Flow; Stereoisomerism; Uterus | 1994 |
Dirofilaria immitis: depression of endothelium-dependent relaxation of canine femoral artery seen in vivo does not persist in vitro.
Topics: Animals; Arginine; Culture Techniques; Dirofilaria immitis; Dirofilariasis; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Femoral Artery; Male; Mefenamic Acid; Methacholine Chloride; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Seasons | 1994 |
Pilocarpine-induced relaxation of rat tail artery by a non-cholinergic mechanism and in the absence of an intact endothelium.
Topics: Acetylcholine; Action Potentials; Animals; Arteries; Autonomic Nervous System; Benzopyrans; Cromakalim; Endothelium, Vascular; Female; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Pilocarpine; Pyrroles; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tail | 1994 |
The mechanism of the vasodilator effect of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa.
Topics: Acetylcholine; Alkaloids; Animals; Arginine; Atropine; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indole Alkaloids; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Phenylephrine; Quinazolines; Rats; Rats, Sprague-Dawley; Triprolidine; Vasodilation; Yohimbine | 1994 |
Evidence against vasoactive intestinal polypeptide as the relaxant neurotransmitter in human cavernosal smooth muscle.
Topics: Arginine; Chymotrypsin; Cyclic GMP; Electric Stimulation; Humans; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Neurotransmitter Agents; Nitric Oxide; Nitroarginine; Penis; Vasoactive Intestinal Peptide | 1993 |
Absence of desensitization to the relaxant activity of streptozotocin in isosorbide dinitrate-tolerant rat aorta.
Topics: Animals; Aorta, Thoracic; Drug Tolerance; Guanylate Cyclase; In Vitro Techniques; Isosorbide Dinitrate; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Papaverine; Phenylephrine; Rats; Streptozocin; Vasodilation | 1993 |
Role of NO in vagally-mediated relaxations of guinea-pig stomach.
Topics: Adrenergic beta-Antagonists; Adrenergic Fibers; Animals; Arginine; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Neurons; Nitric Oxide; Nitroarginine; Nitroglycerin; Stomach; Tetrodotoxin; Vagus Nerve | 1993 |
Dissimilarity in the mechanisms of action of KRN2391, nicorandil and cromakalim in canine renal artery.
Topics: Animals; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitrates; Potassium Channels; Potassium Chloride; Pyridines; Pyrroles; Renal Artery; Vasodilator Agents | 1993 |
Induction by endothelin-1 of epithelium-dependent relaxation of guinea-pig trachea in vitro: role for nitric oxide.
Topics: Animals; Arginine; Endothelins; Epithelium; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; omega-N-Methylarginine; Oxyhemoglobins; Prostaglandins; Trachea | 1993 |
Mechanism of action of KRN2391 in canine coronary vascular bed.
Topics: Animals; Antihypertensive Agents; Arteries; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Dogs; Drug Interactions; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pyridines; Pyrroles; Vasodilator Agents | 1993 |
Notes on the acetylcholine-induced relaxation of porcine coronary arteries.
Topics: Acetylcholine; Animals; Arginine; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Radioimmunoassay; Swine; Vasoconstriction; Vasodilation | 1994 |
Endothelium-dependent relaxation by angiotensin-converting enzyme inhibitors in canine femoral arteries.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Aspirin; Captopril; Dinoprost; Dipeptides; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Indans; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Oxyhemoglobins; Superoxide Dismutase | 1994 |
Vascular mechanisms of cyclosporin-induced hypertension in the rat.
Topics: Acetylcholine; Animals; Blood Pressure; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Endothelins; Hypertension; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Systole; Vascular Resistance | 1994 |
Involvement of nitric oxide and nitrosothiols in relaxation of pulmonary arteries to peroxynitrite.
Topics: Aminoquinolines; Animals; Cattle; Free Radical Scavengers; Glutathione; In Vitro Techniques; Kinetics; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroso Compounds; Potassium; Pulmonary Artery; Time Factors | 1994 |
Changes in cytosolic cGMP and calcium in airway smooth muscle relaxed by 3-morpholinosydnonimine.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Cytosol; Dogs; Female; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth; Osmolar Concentration; Trachea | 1994 |
Different responses to acetylcholine in the presence of nitric oxide inhibitor in rat aortae and mesenteric arteries.
Topics: Acetylcholine; Animals; Aorta; Arginine; Barium; Calcium; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Tetraethylammonium Compounds | 1993 |
Mediators of nicotine-induced relaxations of the rat gastric fundus.
Topics: Animals; Arginine; Chymotrypsin; Female; Gastric Fundus; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nicotine; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide | 1993 |
Methylene blue enhanced photorelaxation in aorta, pulmonary artery and corpus cavernosum.
Topics: Animals; Aorta; Arginine; Cyclic GMP; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Penis; Photosensitizing Agents; Pulmonary Artery; Rabbits; Ultraviolet Rays | 1993 |
Endothelin-3-induced relaxation of rat thoracic aorta: a role for nitric oxide formation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calmodulin; Cyclic GMP; Endothelins; Hemoglobins; Imidazoles; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar | 1993 |
Nitrone spin-traps block calcium channels and induce pulmonary artery relaxation independent of free radicals.
Topics: Animals; Calcium Channels; Catalase; Cells, Cultured; Cyclic N-Oxides; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radicals; In Vitro Techniques; Male; Meclofenamic Acid; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrogen Oxides; Pulmonary Artery; Pyridines; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxide Dismutase | 1993 |
Interactions of nitrovasodilators and atrial natriuretic peptide in isolated dog coronary arteries.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Coronary Vessels; Cyclic GMP; Dinoprost; Dogs; Epoprostenol; Female; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Papaverine; Platelet Aggregation Inhibitors; Vasodilator Agents | 1993 |
Acetylcholine-induced endothelium-independent relaxations in monkey isolated superior and inferior caval veins.
Topics: Acetylcholine; Animals; Arginine; Aspirin; Calcimycin; Dinoprost; Endothelium, Vascular; Female; Glyburide; In Vitro Techniques; Isoproterenol; Macaca; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Tetraethylammonium Compounds; Vena Cava, Inferior; Vena Cava, Superior | 1993 |
Dependence of endotoxin-induced vascular hyporeactivity on extracellular L-arginine.
Topics: Animals; Arginine; In Vitro Techniques; Lipopolysaccharides; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Polymyxin B; Rats; Rats, Wistar; Vasoconstriction | 1993 |
Relaxation of rat thoracic aorta by N-nitroso compounds and nitroprusside and their modifications of nucleic acid bases through release of nitric oxide.
Topics: 2-Acetylaminofluorene; Acetaminophen; Animals; Aorta, Thoracic; Deamination; Dose-Response Relationship, Drug; Female; Hemoglobins; Hydroxylation; Male; Methylene Blue; Methylnitronitrosoguanidine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Nitroso Compounds; Nucleic Acids; Rats; Rats, Wistar | 1993 |
NO- and NO2-carrying molecules potentiate photorelaxation in rat trachea and aorta.
Topics: Animals; Aorta; Arginine; Female; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitrous Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Superoxide Dismutase; Trachea; Ultraviolet Rays | 1993 |
Partial mediation by nitric oxide of the relaxation of human isolated detrusor strips in response to electrical field stimulation.
Topics: Arginine; Electric Stimulation; Humans; In Vitro Techniques; Indomethacin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Propranolol; Tetrodotoxin | 1993 |
5-Hydroxytryptamine induces endothelium-independent relaxations of sheep pulmonary vein: role of cyclic nucleotide.
Topics: Animals; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Pulmonary Veins; Serotonin; Serotonin Receptor Agonists; Sheep | 1995 |
Indigo carmine inhibits endothelium-dependent and -independent vasodilation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcimycin; Dose-Response Relationship, Drug; Endothelium, Vascular; Histamine; In Vitro Techniques; Indigo Carmine; Ionophores; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 1996 |
Force and intracellular Ca2+ during NANC-mediated relaxation of rat anococcygeus muscle and the effects of cyclopiazonic acid.
Topics: Anal Canal; Animals; Arginine; Calcium; Calcium-Transporting ATPases; Electric Stimulation; Enzyme Inhibitors; Guanethidine; Indoles; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Skeletal; Nitroarginine; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum | 1995 |
Involvement of nitric oxide in the non-adrenergic non-cholinergic neurotransmission of horse deep penile arteries: role of charybdotoxin-sensitive K(+)-channels.
Topics: Adrenergic Fibers; Animals; Arginine; Charybdotoxin; Cholinergic Fibers; Electric Stimulation; Endothelium, Vascular; Glyburide; Horses; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NADPH Dehydrogenase; Nerve Fibers; Nitric Oxide; Nitroarginine; Oxyhemoglobins; Penis; Potassium Channels; Sensitivity and Specificity; Signal Transduction; Synaptic Transmission | 1995 |
Nitric oxide synthase induction and relaxation in lipopolysaccharide-treated gastric fundus muscle of rats.
Topics: Animals; Arginine; Dinoprost; Enzyme Induction; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Lipopolysaccharides; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar | 1996 |
beta-Adrenoceptor activates endothelium-dependent release of nitric oxide in rat aorta.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Thoracic; Arginine; Colforsin; Endothelium, Vascular; Female; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 1995 |
Induction of guinea pig airway hyperresponsiveness by inactivation of guanylate cyclase.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Airway Resistance; Analysis of Variance; Animals; Coloring Agents; Cyclic GMP; Dose-Response Relationship, Drug; Epithelium; Guinea Pigs; Histamine; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Purinones; Trachea | 1996 |
Relaxation response to the rat stomach fundus to methylene blue.
Topics: Animals; Atropine; Cyclic AMP; Cyclic GMP; Electric Stimulation; Gastric Fundus; Gastric Mucosa; Guanethidine; In Vitro Techniques; Male; Methylene Blue; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Wistar; Serotonin; Stomach; Sympatholytics | 1996 |
Carbon monoxide-induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Cyclic GMP; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Enzyme Inhibitors; Female; Guanylate Cyclase; Indomethacin; Light; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide Synthase; Oxygen; Pregnancy; Sheep | 1996 |
Monkey central retinal artery is innervated by nitroxidergic vasodilator nerves.
Topics: Animals; Calcitonin Gene-Related Peptide; Coloring Agents; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Female; Ganglionic Stimulants; Immunoenzyme Techniques; Isometric Contraction; Macaca; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nerve Endings; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxyhemoglobins; Retinal Artery; Sympathetic Nervous System; Vasodilation | 1996 |
MCI-154-induced relaxation in vascular smooth muscles of guinea pig.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Endothelium, Vascular; Femoral Artery; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Pyridazines; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Evidence that guanylate cyclase is involved in modulating the resting tension and neurally-induced contraction of the guinea pig tracheal muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic GMP; Electric Stimulation; Guanylate Cyclase; Guinea Pigs; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Phosphodiesterase Inhibitors; Rest; Trachea | 1996 |
Investigations of the function of the vascular endothelium in portal hypertensive rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Analysis of Variance; Animals; Coloring Agents; Disease Models, Animal; Endothelium, Vascular; Hypertension, Portal; Male; Mesenteric Arteries; Methylene Blue; Microspheres; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Thromboxane A2; Vasoconstrictor Agents | 1995 |
Mechanism of hydroxyl radical-induced modulation of vascular tone.
Topics: Animals; Aorta; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hydroxyl Radical; Indomethacin; Mannitol; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rabbits | 1997 |
Analysis of relaxation and repolarization mechanisms of nicorandil in rat mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Electrophysiology; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Mechanism of adrenomedullin-induced relaxation in isolated canine retinal arteries.
Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Dogs; Endothelium, Vascular; Enzyme Inhibitors; Female; Glyburide; Hypoglycemic Agents; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Peptides; Retinal Artery; Vasodilator Agents | 1997 |
Involvement of a glibenclamide-sensitive mechanism in the nitrergic neurotransmission of the pig intravesical ureter.
Topics: Animals; Female; Glyburide; Guanylate Cyclase; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Potassium Channel Blockers; Swine; Ureter | 1997 |
Carbon monoxide-induced relaxation and distribution of haem oxygenase isoenzymes in the pig urethra and lower oesophagogastric junction.
Topics: Animals; Carbon Monoxide; Cyclic AMP; Cyclic GMP; Esophagogastric Junction; Heme Oxygenase (Decyclizing); Isoenzymes; Methylene Blue; Muscle Relaxation; Potassium Channel Blockers; Swine; Urethra | 1997 |
Endothelium-independent relaxation of aortic rings by the nitric oxide synthase inhibitor diphenyleneiodonium.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hot Temperature; Male; Methylene Blue; Muscle Relaxation; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Onium Compounds; Prazosin; Rats; Rats, Sprague-Dawley | 1997 |
Relaxant effects of vasoactive intestinal peptide on pulmonary artery in chronically hypoxic rats.
Topics: Animals; Cyclooxygenase Inhibitors; Guanylate Cyclase; Hypoxia; Indomethacin; Male; Masoprocol; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Wistar; Vasoactive Intestinal Peptide | 1996 |
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors.
Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxyhemoglobins; Pyrroles; Vasodilator Agents | 1997 |
Loss of acetylcholine-induced relaxation by M3-receptor activation in mesenteric arteries of spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Calcimycin; Enzyme Inhibitors; Hypertension; Ionophores; Male; Mesenteric Arteries; Methylene Blue; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Purinergic P1 Receptor Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Muscarinic | 1997 |
Macrophage-induced nitric oxide and prostanoid dependent relaxation of arterial smooth muscles.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arteries; Aspirin; Cells, Cultured; Dogs; Enzyme Inhibitors; Indomethacin; Lipopolysaccharides; Macrophages, Peritoneal; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Vasodilation | 1997 |
Ex vivo study of the increased sensitivity to NO of endothelium-denuded thoracic aortas isolated from dietary magnesium-deficient rats.
Topics: Animals; Aorta, Thoracic; Cromakalim; Cyclic GMP; Diet; Endothelium, Vascular; In Vitro Techniques; Magnesium Deficiency; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroprusside; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar | 1997 |
Effect of dietary salt loading and high-calcium diet on vascular smooth muscle responses and endothelium function in rats.
Topics: Acetylcholine; Animals; Calcium; Diet; Dose-Response Relationship, Drug; Endothelium, Vascular; Histamine; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1997 |
Polycyclic aromatic hydrocarbons-induced vasorelaxation through activation of nitric oxide synthase in endothelium of rat aorta.
Topics: Acenaphthenes; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Polycyclic Aromatic Hydrocarbons; Rats; Rats, Wistar; Vasodilation | 1997 |
Nitric oxide-induced ciliary muscle relaxation during contraction with endothelin-1 is mediated through elevation of cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Ciliary Body; Cyclic GMP; Drug Combinations; Endothelin-1; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors | 1997 |
Difference in the endothelium mediated effects of A23187 on thoracic aorta between neonatal and adult guinea pigs.
Topics: Animals; Animals, Newborn; Aorta, Thoracic; Calcimycin; Carbachol; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; Norepinephrine; Vasodilator Agents | 1997 |
Decreased endothelium-dependent vasoconstriction to noradrenaline in acute-stressed rats is potentiated by previous chronic stress: nitric oxide involvement.
Topics: Acute Disease; Animals; Aorta; Chronic Disease; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Wistar; Stress, Physiological; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Regional differences in the vasorelaxant effects of nicorandil and amlodipine on isolated porcine coronary arteries.
Topics: Amlodipine; Animals; Calcium; Calcium Channel Blockers; Coronary Vessels; Enzyme Activation; Extracellular Space; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pericardium; Potassium; Potassium Channels; Swine; Vasodilation; Vasodilator Agents | 1998 |
Nitric oxide relaxes bovine ciliary muscle contracted by carbachol through elevation of cyclic GMP.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carbachol; Cattle; Ciliary Body; Cyclic AMP; Dose-Response Relationship, Drug; Drug Combinations; Indicators and Reagents; Methylene Blue; Miotics; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroprusside | 1998 |
The role of cGMP in the relaxation to nitric oxide donors in airway smooth muscle.
Topics: Aminoquinolines; Animals; Antidotes; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Isometric Contraction; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Swine | 1998 |
Halothane attenuates nitric oxide relaxation of rat aortas by competition for the nitric oxide receptor site on soluble guanylyl cyclase.
Topics: Aminoquinolines; Anesthetics, Inhalation; Animals; Aorta, Thoracic; Binding, Competitive; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Halothane; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 1998 |
Regulation of ductus arteriosus patency by nitric oxide in fetal lambs: the role of gestation, oxygen tension, and vasa vasorum.
Topics: Aminoquinolines; Animals; Aorta; Calcimycin; Ductus Arteriosus; Ductus Arteriosus, Patent; Enzyme Inhibitors; Female; Fetus; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxygen; Partial Pressure; Polymerase Chain Reaction; Pregnancy; Sheep; Vasa Vasorum | 1998 |
cGMP-independent mechanism of airway smooth muscle relaxation induced by S-nitrosoglutathione.
Topics: Acetylcholine; Animals; Cyclic AMP; Cyclic GMP; Cytosol; Dithiothreitol; Dogs; Enzyme Inhibitors; Female; Glutathione; Guanylate Cyclase; In Vitro Techniques; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitroso Compounds; S-Nitrosoglutathione; Trachea | 1998 |
Effects of methylene blue and indomethacin on sodium nitroprusside-induced relaxations of the guinea pig tracheal smooth muscle.
Topics: Animals; Carbachol; Cyclooxygenase Inhibitors; Guanylate Cyclase; Guinea Pigs; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Trachea | 1998 |
Nitroglycerin-induced aortic relaxation mediated by calcium-activated potassium channel is markedly diminished in hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Calcium; Charybdotoxin; Guanylate Cyclase; Hypertension; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Is nitric oxide involved in 5-HT3 receptor-mediated neurogenic relaxation of guinea pig proximal colon?
Topics: Animals; Colon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hemoglobins; In Vitro Techniques; Indoles; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tropisetron | 1998 |
Endothelium-dependent relaxation induced by hawthorn extract in rat mesenteric artery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Plant Extracts; Potassium; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Rosales | 1998 |
Comparison of two soluble guanylyl cyclase inhibitors, methylene blue and ODQ, on sodium nitroprusside-induced relaxation in guinea-pig trachea.
Topics: Animals; Cyclic GMP; Drug Interactions; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Methylene Blue; Mice; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxadiazoles; Quinoxalines; Signal Transduction; Solubility; Trachea; Vasodilator Agents | 1998 |
Role of endothelium and adventitia on eugenol-induced relaxation of rabbit ear artery precontracted by histamine.
Topics: Animals; Ear; Endothelium, Vascular; Enzyme Inhibitors; Eugenol; Histamine; Male; Membrane Potentials; Methylene Blue; Molecular Structure; Muscle Contraction; Muscle Relaxation; Nitroarginine; Norepinephrine; Phenol; Rabbits; Vasodilation | 1998 |
Endothelium-derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats.
Topics: Acetylcholine; Animals; Apamin; Blood Pressure; Body Weight; Bridged Bicyclo Compounds, Heterocyclic; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Glyburide; Hydrazines; Hypertension; In Vitro Techniques; Indomethacin; Membrane Potentials; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Nitroprusside; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole; Tetraethylammonium; Vasodilation; Vasodilator Agents | 1999 |
[The role of guanylate cyclase and arachidonic acid metabolites in the regulation of epithelium-dependent relaxation in the smooth muscle from the rat trachea].
Topics: Adrenergic alpha-Agonists; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Epithelium; Guanylate Cyclase; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Phenylephrine; Rats; Trachea | 1999 |
Cyclic GMP regulates cromakalim-induced relaxation in the rat aortic smooth muscle: role of cyclic GMP in K(ATP)-channels.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Apamin; Calcium; Charybdotoxin; Cromakalim; Cyclic GMP; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Inbred WKY | 1999 |
Pharmacological characterization of metamizol-induced relaxation in phenylephrine-precontracted rabbit thoracic aorta smooth muscle.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Dipyrone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glyburide; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Ouabain; Phenylephrine; Rabbits; Sodium-Potassium-Exchanging ATPase; Tetraethylammonium; Time Factors; Vasoconstrictor Agents | 1999 |
The relaxant activity of the methanolic extract of Acanthus montanus on intestinal smooth muscles.
Topics: Animals; Colon; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Intestines; Isoproterenol; Jejunum; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Phentolamine; Plant Extracts; Potassium Chloride; Procaine; Propranolol; Rabbits | 1999 |
Vasodilator effects of organotransition-metal nitrosyl complexes, novel nitric oxide donors.
Topics: Animals; Drug Tolerance; Endothelium, Vascular; Enzyme Inhibitors; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroglycerin; Nitroprusside; Organometallic Compounds; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2000 |
The effect of cyclic GMP on rabbit corporal smooth muscle tone and its modulation by cyclo-oxygenase products.
Topics: Acetylcholine; Aminoquinolines; Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Penis; Prostaglandin-Endoperoxide Synthases; Rabbits | 2000 |
In vitro relaxation of rabbit and human internal anal sphincter by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa.
Topics: Acetylcholine; Alkaloids; Anal Canal; Animals; Calcium; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Edetic Acid; Enzyme Inhibitors; Ethylmaleimide; Humans; In Vitro Techniques; Indole Alkaloids; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Quinazolines; Rabbits; Species Specificity; Vasodilator Agents | 2000 |
Cyclic GMP-dependent relaxation of isolated rat renal glomeruli induced by extracellular ATP.
Topics: Adenosine Triphosphate; Animals; Citrulline; Cyclic GMP; Enzyme Inhibitors; Extracellular Space; Guanylate Cyclase; In Vitro Techniques; Inulin; Kidney Glomerulus; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Rats; Rats, Wistar; Receptors, Purinergic P2 | 2001 |
Endothelium-dependent vasorelaxant and antiproliferative effects of apigenin.
Topics: Animals; Aorta, Thoracic; Apigenin; Cell Division; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Flavonoids; Isometric Contraction; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Thymidine | 2000 |
Different mechanisms of hypoxic relaxation in canine coronary arteries and rat abdominal aortas.
Topics: Aminoquinolines; Animals; Aorta, Abdominal; Arginine; Coronary Vessels; Dinoprost; Dogs; Endothelium, Vascular; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Oxygen; Rats; SRS-A; Vascular Resistance; Vasodilation | 1992 |
Effect of methylene blue on the vesicourethral function in the rats.
Topics: Anesthesia; Animals; Injections, Intra-Arterial; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Rats; Urethra; Urinary Bladder | 1992 |
Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission.
Topics: Adult; Aged; Arginine; Cyclic GMP; Electric Stimulation; Erectile Dysfunction; Humans; Male; Methylene Blue; Middle Aged; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Organ Culture Techniques; Penile Erection; Penis; Purinones; Synaptic Transmission | 1992 |
Pharmacological interaction experiments differentiate between glibenclamide-sensitive K+ channels and cyclic GMP as components of vasodilation by nicorandil.
Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Drug Interactions; Glyburide; Guanidines; In Vitro Techniques; Methylene Blue; Molsidomine; Muscle Relaxation; Niacinamide; Nicorandil; Nitroprusside; Pinacidil; Potassium Channels; Pyrroles; Sensitivity and Specificity; Vasodilator Agents | 1992 |
Involvement of cyclic GMP in non-adrenergic, non-cholinergic inhibitory neurotransmission in dog proximal colon.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Autonomic Nervous System; Colon; Cyclic GMP; Dogs; Electric Stimulation; Female; Gastrointestinal Motility; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinones; Signal Transduction; Synaptic Transmission | 1992 |
Role of nitric oxide and guanosine 3',5'-cyclic monophosphate in mediating nonadrenergic, noncholinergic relaxation in guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Autonomic Nervous System; Cyclic GMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Oxidopamine; Phosphodiesterase Inhibitors; Purinones; Pyrogallol; Sympathectomy, Chemical | 1992 |
Possible mechanisms of age-associated reduction of vascular relaxation caused by atrial natriuretic peptide.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Purinones; Rats; Rats, Inbred Strains | 1992 |
Guanylate cyclase inhibitors: effect on tone, relaxation, and cGMP content of lower esophageal sphincter.
Topics: Animals; Calcium; Cyclic GMP; Cystamine; Electric Stimulation; Esophagogastric Junction; Female; Guanylate Cyclase; Male; Membrane Potentials; Methylene Blue; Muscle Relaxation; Muscle Tonus; Opossums; Rest | 1992 |
Involvement of nitric oxide pathway in the PAF-induced relaxation of rat thoracic aorta.
Topics: Aging; Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar | 1992 |
Human alpha-calcitonin gene-related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Guanylate Cyclase; Hemoglobins; Ibuprofen; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Rats; Rats, Sprague-Dawley; Second Messenger Systems | 1992 |
A mediator derived from arginine mediates inhibitory junction potentials and relaxations in lower esophageal sphincter: an independent role for vasoactive intestinal peptide.
Topics: Animals; Arginine; Carbachol; Dogs; Electrophysiology; Esophagogastric Junction; Female; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Neuromuscular Junction; NG-Nitroarginine Methyl Ester; Nitroprusside; Opossums; Scorpion Venoms; Tetrodotoxin; Vasoactive Intestinal Peptide | 1992 |
Effects of noise on blood pressure and vascular reactivities.
Topics: Animals; Aorta, Thoracic; Arginine; Blood Pressure; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Nitroarginine; Noise; Phenylephrine; Potassium; Rats; Rats, Sprague-Dawley; Serotonin; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1992 |
Glibenclamide does not block arterial relaxation caused by vasoactive intestinal polypeptide.
Topics: Animals; Carbachol; Endothelium, Vascular; Female; Glyburide; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Vasoactive Intestinal Peptide; Vasodilation | 1992 |
Endothelium-dependent and -independent relaxation by dopamine in the rabbit pulmonary artery.
Topics: Animals; Dopamine; Dopamine Antagonists; Endothelium, Vascular; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Pulmonary Artery; Rabbits; Receptors, Dopamine; Superoxide Dismutase | 1992 |
L-arginine induces relaxation of small mesenteric arteries from endotoxin-treated rats.
Topics: Animals; Arginine; Endotoxins; Escherichia coli; In Vitro Techniques; Lipopolysaccharides; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Strains; Vascular Resistance | 1992 |
Pharmacological evaluation of GS-389, a novel tetrahydroisoquinoline analog related to higenamine, on vascular smooth muscle.
Topics: Alkaloids; Animals; Aorta, Thoracic; Bicarbonates; Cardiotonic Agents; Drug Interactions; Egtazic Acid; Endothelium, Vascular; Female; In Vitro Techniques; Isoquinolines; Male; Methylene Blue; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Papaverine; Phenylephrine; Rats; Rats, Inbred Strains; Tetrahydroisoquinolines; Vasodilator Agents | 1992 |
The mode of vasorelaxing action of melatonin in rabbit aorta.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Dinoprost; In Vitro Techniques; Male; Melatonin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Purinones; Rabbits; Serotonin | 1991 |
L-arginine induces relaxation of rat aorta possibly through non-endothelial nitric oxide formation.
Topics: Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains | 1991 |
The calcium channel antagonist S 11568 causes endothelium-dependent relaxation in canine arteries.
Topics: Animals; Arginine; Calcium Channel Blockers; Cyclic GMP; Dihydropyridines; Dogs; Endothelium, Vascular; Female; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine | 1991 |
The effect of inhibitors of nitric oxide biosynthesis and cyclic GMP formation on nerve-evoked relaxation of human cavernosal smooth muscle.
Topics: Arginine; Autonomic Nervous System; Cyclic GMP; Electric Stimulation; Guanethidine; Humans; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; Penis; Synaptic Transmission | 1991 |
Calcitonin gene-related peptide (CGRP)-induced cyclic AMP, cyclic GMP and vasorelaxant responses in rat thoracic aorta are antagonized by blockers of endothelium-derived relaxant factor (EDRF).
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Hemoglobins; Indomethacin; Male; Masoprocol; Methylene Blue; Muscle Relaxation; Nitric Oxide; Norepinephrine; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Mechanism of vasodilatory effect of berberine in rat mesenteric artery.
Topics: Animals; Arginine; Berberine; Caffeine; Calcium Channels; Drug Interactions; Endothelium, Vascular; Female; Male; Mesenteric Arteries; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Phenylephrine; Potassium; Rats; Rats, Inbred Strains; Vasodilator Agents; Verapamil | 1991 |
Vasorelaxing action of melatonin in rat isolated aorta; possible endothelium dependent relaxation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Endothelium, Vascular; In Vitro Techniques; Male; Melatonin; Methylene Blue; Methysergide; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitroglycerin; Purinones; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid.
Topics: Animals; Arginine; Food; Guanylate Cyclase; Guinea Pigs; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pressure; Reflex; Stomach | 1991 |
Relationship between cyclic guanosine monophosphate accumulation and relaxation of canine trachealis induced by nitrovasodilators.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dogs; Drug Synergism; Female; Guanylate Cyclase; Hemoglobins; Isoproterenol; Male; Methylene Blue; Muscle Relaxation; Nitroglycerin; Nitroprusside; Penicillamine; Purinones; S-Nitroso-N-Acetylpenicillamine; Time Factors; Trachea; Vasodilator Agents | 1991 |
Comparison of the effects of the novel vasodilator FK409 with those of nitroglycerin in isolated coronary artery of the dog.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Coronary Vessels; Dogs; Female; Guanylate Cyclase; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Nitro Compounds; Nitroglycerin; Prostaglandin Endoperoxides, Synthetic; Purinones; Vasodilator Agents | 1991 |
Nicorandil: differential contribution of K+ channel opening and guanylate cyclase stimulation to its vasorelaxant effects on various endothelin-1-contracted arterial preparations. Comparison to aprikalim (RP 52891) and nitroglycerin.
Topics: Animals; Coronary Vessels; Endothelins; Endothelium, Vascular; Glyburide; Guanylate Cyclase; Heart; Hemodynamics; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Picolines; Potassium Channels; Purinones; Pyrans; Rats; Rats, Inbred Strains; Stimulation, Chemical; Swine; Swine, Miniature; Vasodilator Agents | 1991 |
Nitroxergic nerves mediate vagally induced relaxation in the isolated stomach of the guinea pig.
Topics: Animals; Arginine; Atropine; Guanethidine; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Methylene Blue; Models, Biological; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Reflex; Stomach; Vagus Nerve | 1991 |
Contractile and relaxant effects of alpha-adrenergic agonists on rat aorta.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Clonidine; Endothelium, Vascular; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Oxymetazoline; Phenylephrine; Rats | 1991 |
Dual mechanism of the relaxing effect of nicorandil by stimulation of cyclic GMP formation and by hyperpolarization.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Barium; Cattle; Coronary Vessels; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Junction; Niacinamide; Nicorandil; Nitroprusside; Potassium; Potassium Channels; Prostaglandin Endoperoxides, Synthetic; Vasodilator Agents | 1991 |
Heterogeneous involvement of endothelium in calcitonin gene-related peptide-induced relaxation in coronary arteries from rat.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Endothelium, Vascular; Glyburide; Humans; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Ruthenium Red; Substance P | 1991 |
Effect of carbenoxolone on the biological activity of nitric oxide: relation to gastroprotection.
Topics: Animals; Aorta; Arginine; Carbenoxolone; Gastric Mucosa; Humans; Iloprost; In Vitro Techniques; Male; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle Tonus; Neutrophils; Nitric Oxide; Nitroarginine; Nitroprusside; Oxyhemoglobins; Rats; Rats, Inbred Strains; Stomach Ulcer; Vasodilator Agents | 1991 |
Electrically-induced, nerve-mediated relaxation of rabbit urethra involves nitric oxide.
Topics: Animals; Arginine; Arginine Vasopressin; Dose-Response Relationship, Drug; Electric Stimulation; Endothelins; Female; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rabbits; Urethra | 1992 |
Different mechanisms of relaxation of pig coronary artery to bradykinin and cromakalim are distinguished by potassium channel blockers.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Benzopyrans; Bradykinin; Calcium; Coronary Vessels; Cromakalim; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Potassium Channels; Procaine; Pyrroles; Quinine; Swine; Tetraethylammonium; Tetraethylammonium Compounds | 1992 |
Endothelium-dependent rat aortic relaxation to the aqueous leaf extract of Musanga cecropioides.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Vasodilator Agents | 1991 |
Endothelium-independent relaxation of rabbit coronary artery by 17 beta-oestradiol in vitro.
Topics: Animals; Aorta, Thoracic; Arginine; Calcium Channel Blockers; Coronary Vessels; Endothelium, Vascular; Estradiol; Female; Hemoglobins; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pregnancy; Rabbits; Rats; Rats, Inbred Strains | 1991 |
Basal and acetylcholine-stimulated nitric oxide formation mediates relaxation of rabbit cavernous smooth muscle.
Topics: Acetylcholine; Animals; Arginine; Atropine Derivatives; Endothelium; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Parasympatholytics; Penis; Rabbits | 1991 |
Study on the mechanism of carbon monoxide induced endothelium-independent relaxation in porcine coronary artery and vein.
Topics: Animals; Carbon Monoxide; Coronary Vessels; Cyclic GMP; Dinoprost; Enzyme Activation; Guanylate Cyclase; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Signal Transduction; Swine | 1990 |
Vascular smooth muscle relaxation by endothelium-dependent beta 1-adrenergic action.
Topics: Animals; Aorta; Cyclic GMP; Endothelium, Vascular; Indomethacin; Male; Methylene Blue; Metoprolol; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Yohimbine | 1990 |
Acetylcholine-induced release of endothelium-derived relaxing factor from lymphatic endothelial cells.
Topics: Acetylcholine; Animals; Arginine; Aspirin; Atropine; Dogs; Endothelium; Female; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Oxyhemoglobins; Thoracic Duct | 1991 |
Endothelium-dependent effects of pentoxifylline in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Colforsin; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Pentoxifylline; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Endothelium-dependent influence of small changes in extracellular magnesium concentration on the tone of feline middle cerebral arteries.
Topics: Amiloride; Animals; Cats; Cerebral Arteries; Endothelium, Vascular; Female; In Vitro Techniques; Kinetics; Magnesium; Male; Methylene Blue; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Norepinephrine; Oxyhemoglobins; Vasodilation | 1991 |
Pertussis toxin inhibits endothelium-dependent relaxations evoked by fluoride.
Topics: Acetylcholine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Chlorides; Coronary Vessels; Dinoprost; Dogs; Female; Fluorides; GTP-Binding Proteins; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Pertussis Toxin; Propranolol; Virulence Factors, Bordetella | 1990 |
Potentiation of nonadrenergic neural relaxation in guinea pig airways by a cyclic cAMP phosphodiesterase inhibitor.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Ethylmaleimide; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Potassium Chloride; Pyrazines; Tetrodotoxin; Trachea; Vasoactive Intestinal Peptide | 1990 |
Pharmacological differentiation of epithelium-derived relaxing factor from nitric oxide.
Topics: Animals; Arginine; Endothelium, Vascular; Guinea Pigs; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Nitric Oxide; omega-N-Methylarginine; Trachea | 1990 |
Endothelium-dependent vascular activities of endothelin-like peptides in the isolated superior mesenteric arterial bed of the rat.
Topics: Animals; Arginine; Blood Pressure; Cholic Acids; Endothelins; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Inbred Strains; Vasoconstriction; Viper Venoms | 1990 |
Vascular smooth muscle relaxation induced by epidermal growth factor is endothelium-dependent.
Topics: Animals; Aorta, Thoracic; Aspirin; Atropine; Dinoprost; Endothelium, Vascular; Epidermal Growth Factor; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Potassium; Rats; Rats, Inbred Strains | 1990 |
Pharmacological evaluation of a guinea-pig tracheal epithelium-derived inhibitory factor (EpDIF).
Topics: Animals; Aorta, Thoracic; Biological Factors; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Histamine; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Parasympathomimetics; Rats; Rats, Inbred Strains; Trachea | 1990 |
The relaxant action of nicorandil in guinea-pig isolated trachealis.
Topics: Aminophylline; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Isoproterenol; Male; Membrane Potentials; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Niacinamide; Nicorandil; Nitrates; Nitroprusside; Potassium; Propranolol; Receptors, Adrenergic, beta; Rubidium; Tetraethylammonium Compounds; Trachea; Vasodilator Agents | 1986 |
Studies on the mechanism of the vasodilator action of nicorandil.
Topics: Acetylcholine; Animals; Aorta; Arteriosclerosis; Endothelium, Vascular; Guanylate Cyclase; Ion Channels; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Norepinephrine; Potassium; Rabbits; Vasodilation | 1988 |
Dirofilaria immitis: alteration of endothelium-dependent relaxation in the in vivo canine femoral artery.
Topics: Acetylcholine; Animals; Dirofilaria immitis; Dirofilariasis; Dogs; Endothelium, Vascular; Epoprostenol; Femoral Artery; Lipoxygenase Inhibitors; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Vasoconstriction; Vasodilation | 1989 |
S-nitrosothiols as vasodilators: implications regarding tolerance to nitric oxide-containing vasodilators.
Topics: Acetylcysteine; Animals; Ascorbic Acid; Cattle; Chromatography, High Pressure Liquid; Coronary Vessels; Cystine; Drug Tolerance; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1989 |
Contraction followed by relaxation in response to hypoxia in the sheep isolated middle cerebral artery.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cerebral Arteries; Endothelium; Hypoxia; Indomethacin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Quinacrine; Serotonin; Sheep | 1989 |
Actions of a newly synthesized nitro-compound, E-4701, on rabbit vascular smooth muscles.
Topics: Acetylcholine; Animals; Calcium; Coronary Circulation; Dioxanes; Dioxins; Membrane Potentials; Mesenteric Arteries; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Rabbits; Sodium; Swine | 1989 |
Glibenclamide is a competitive antagonist of cromakalim, pinacidil and RP 49356 in guinea-pig pulmonary artery.
Topics: Animals; Benzopyrans; Cromakalim; Glyburide; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Picolines; Pinacidil; Potassium Channels; Potassium Chloride; Pulmonary Artery; Purinones; Pyrans; Pyrroles; Tetraethylammonium Compounds | 1989 |
Cyclic GMP: a potential mediator of neurally- and drug-induced relaxation of opossum lower esophageal sphincter.
Topics: Animals; Cyclic GMP; Electric Stimulation; Esophagogastric Junction; Female; Male; Methylene Blue; Muscle Relaxation; Nitroprusside; Opossums; Purinones | 1989 |
Vascular relaxing effects of bumetanide.
Topics: Angiotensin II; Animals; Bumetanide; Carotid Arteries; Diuretics; Dogs; Endothelium, Vascular; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Vasodilator Agents | 1989 |
Pertussis toxin inhibits endothelium-dependent relaxations to certain agonists in porcine coronary arteries.
Topics: Adenylate Cyclase Toxin; Animals; Brimonidine Tartrate; Coronary Vessels; Endothelium, Vascular; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Oxyhemoglobins; Pertussis Toxin; Platelet Aggregation; Quinoxalines; Serotonin; Swine; Thrombin; Virulence Factors, Bordetella | 1989 |
Some electrical properties of the endothelium-dependent hyperpolarization recorded from rat arterial smooth muscle cells.
Topics: Acetylcholine; Animals; Atropine; Endothelium, Vascular; Female; Histamine; Male; Membrane Potentials; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Pyrilamine; Rats | 1989 |
Vascular relaxation mediated by hydroxylamines and oximes: their conversion to nitrites and mechanism of endothelium dependent vascular relaxation.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemoglobins; Hydroxylamines; In Vitro Techniques; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Oximes; Rats; Vasodilator Agents | 1989 |
Endothelium-dependent calcium-induced relaxation in the presence of Ca2+-antagonists in canine depolarized coronary arteries.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Vessels; Dogs; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Oxyhemoglobins | 1989 |
Mechanisms of endothelium-dependent vascular smooth muscle relaxation elicited by bradykinin and VIP.
Topics: Animals; Bradykinin; Cattle; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Indomethacin; Methylene Blue; Muscle Contraction; Muscle Relaxation; Potassium; Vasoactive Intestinal Peptide; Vasodilation | 1987 |
Endothelial potentiation of relaxation response to phentolamine in rat thoracic aorta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Phentolamine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasodilation | 1988 |
A comparison of the action of the endothelium-derived relaxant factor and the inhibitory factor from the bovine retractor penis on rabbit aortic smooth muscle.
Topics: Animals; Carbachol; Catechols; Cattle; Endothelium; Flurbiprofen; Guanylate Cyclase; In Vitro Techniques; Male; Masoprocol; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Neural Inhibition; Neurotransmitter Agents; Nitric Oxide; Nitroprusside; Norepinephrine; Penis; Quinacrine; Rabbits; Vasodilator Agents | 1986 |
Stimulation of soluble coronary arterial guanylate cyclase by SIN-1.
Topics: Animals; Cations, Divalent; Cattle; Coronary Vessels; Cyclic GMP; Ferricyanides; Guanylate Cyclase; In Vitro Techniques; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Oxadiazoles; Sodium Nitrite; Sulfhydryl Compounds; Sydnones | 1986 |
Palytoxin-induced endothelium-dependent relaxation in the isolated rat aorta.
Topics: Acrylamides; Animals; Aorta, Thoracic; Carbachol; Cnidarian Venoms; Endothelium; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains | 1987 |
Pharmacological actions of synthetic atrial natriuretic factor on coronary vascular smooth muscle.
Topics: Animals; Atrial Natriuretic Factor; Cats; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Guanylate Cyclase; Hormones; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Papillary Muscles; Peptide Fragments; Perfusion; Vasodilation | 1988 |
Comparison of atriopeptins II and III, VIP and beta 2-adrenoceptor-evoked relaxations of the two layers of smooth muscle in the rat portal vein.
Topics: Animals; Atrial Natriuretic Factor; Atropine; Female; Isoproterenol; Methoxamine; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Portal Vein; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide | 1987 |
Effects of atrial natriuretic factor, sodium nitroprusside, and acetylcholine on cyclic GMP levels and relaxation in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Colforsin; Cyanides; Cyclic GMP; Ferricyanides; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Potassium Chloride; Rats; Sodium-Potassium-Exchanging ATPase | 1985 |
Isosorbide 5-mononitrate effects on isolated rabbit aorta and vena cava: relationship between cyclic GMP and relaxation of vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Female; In Vitro Techniques; Isosorbide Dinitrate; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Vena Cava, Inferior | 1985 |
Cyclic GMP as the mediator of molsidomine-induced vasodilatation.
Topics: Animals; Cattle; Coronary Vessels; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Endothelium; In Vitro Techniques; Methylene Blue; Molsidomine; Muscle Relaxation; Muscle, Smooth, Vascular; Oxadiazoles; Phosphodiesterase Inhibitors; Sydnones; Time Factors; Vasodilation | 1986 |
Endothelial modulation of vascular relaxation to nitrovasodilators in aging and hypertension.
Topics: Aging; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium; Hypertension; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Nitrite; Vasodilator Agents | 1986 |
Lysolecithins as endothelium-dependent vascular smooth muscle relaxants that differ from endothelium-derived relaxing factor (nitric oxide)
Topics: Acetylcholine; Animals; Biological Factors; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemoglobins; Indomethacin; Lysophosphatidylcholines; Male; Masoprocol; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Rabbits | 1988 |
Endothelium-derived relaxing factor released from cultured cells: differentiation from nitric oxide.
Topics: Animals; Aorta, Thoracic; Arteries; Bradykinin; Cattle; Cells, Cultured; Endothelium, Vascular; Guinea Pigs; Hemoglobins; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Nitric Oxide; Rabbits; Trachea | 1988 |
Pharmacological analysis of nicotinic relaxation of bovine retractor penis muscle.
Topics: Acetylcholine; Animals; Carbachol; Cattle; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Hexamethonium Compounds; Lidocaine; Male; Mecamylamine; Methylene Blue; Muscle Contraction; Muscle Relaxation; Nicotine; Oxygen; Penis; Scopolamine; Tetrodotoxin | 1988 |
The role of lysolecithin in the relaxation of vascular smooth muscle.
Topics: Animals; Aorta; Hemoglobins; In Vitro Techniques; Lysophosphatidylcholines; Male; Masoprocol; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Octoxynol; Polyethylene Glycols; Rabbits | 1987 |
Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries.
Topics: Animals; Benzoquinones; Chlorpheniramine; Cimetidine; Coronary Vessels; Dogs; Female; Histamine; Indomethacin; Macaca; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Quinones; Vasodilation | 1986 |