Page last updated: 2024-08-17

methylene blue and Disease Models, Animal

methylene blue has been researched along with Disease Models, Animal in 173 studies

Research

Studies (173)

TimeframeStudies, this research(%)All Research%
pre-19907 (4.05)18.7374
1990's15 (8.67)18.2507
2000's33 (19.08)29.6817
2010's96 (55.49)24.3611
2020's22 (12.72)2.80

Authors

AuthorsStudies
Bezuidenhout, B; Birkholtz, LM; Chibale, K; Churchyard, A; Coetzer, TL; Egan, TJ; Fontinha, D; Gibhard, L; Lauterbach, S; Mayoka, G; Njoroge, M; Okombo, J; Prudêncio, M; Reader, J; Sanches-Vaz, M; van der Watt, M; Wittlin, S; Yeates, C1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Beldi, VF; Evora, PRB; Farina, JA; Moriguti, EK; Nunes, AA; Rosique, MJ; Tirapelli, LF1
Cui, ZQ; He, RJ; Hou, GL; Luo, Y; Wang, YF; Yi, YL; Zhang, HY; Zhang, Y1
Chen, L; Dong, D; Liu, C; Liu, T; Wang, H; Yuan, M1
Albuquerque, AAS; de Castro, RSAP; Evora, PRB; Ferreira, CHF; Gonçalves-Ferri, WA; Oharomari, LK; Silva Lessa, DF1
Genrikhs, EE; Guschina, AS; Isaev, NK; Novikova, SV; Olshanskij, AS; Shedenkova, MO; Stavrovskaya, AV; Stelmashook, EV; Voronkov, DN; Yamshikova, NG1
Mahajan, S; Mudher, A; Rouiz Ortega, ED; Skoulakis, EMC; Vourkou, E1
Aderibigbe, AO; Ajayi, AM; Ben-Azu, B; Iwalewa, EO; Umukoro, S1
Cranston, A; Harrington, CR; Klein, J; Kondak, C; Lauer, D; Magbagbeolu, M; Melis, V; Niewiadomska, G; Riedel, G; Santos, RX; Schwab, K; Steczkowska, M; Theuring, F; Wischik, CM; Wydrych, M; Zadrozny, M1
Albuquerque, AAS; Capellini, VK; Carvalho, MTM; Celotto, AC; Evora, PRB; Ferreira, LG1
Boley, SP; Corcoran, JN; Engebretsen, KM; LeRoy, JM; Stellpflug, SJ1
Dong, Y; Lu, Y; Wen, J; Xu, J; Yang, L; Zhang, G; Zhang, Q1
Carvalho, LJM; Nugraha, AB; Sivakumar, T; Tuvshintulga, B; Yokoyama, N1
Cho, EYP; Fung, JCL1
El Okle, OS; Goma, AA; Tohamy, HG1
Baccanale, CL; de Castro Brás, LE; Eccleston, L; Meggs, WJ; O'Rourke, D; Pittman, P; Sloan, T; St Antoine, JC; Verzwyvelt, SM1
Butler, D; D'Brant, L; Hu, S; Huang, R; Koetzner, CA; Kramer, LD; Kuo, L; Lang, Y; Li, H; Li, Z; Rugenstein, N; Sakamuru, S; Samrat, S; Tharappel, A; Trudeau, N; Xia, M; Zhang, J1
Han, HC; Lee, SW; Moon, SW; Park, JS; Suh, HR1
Arias, JL; Arias, N; Fidalgo, C; Méndez, M1
Chen, C; Chen, J; Chen, X; Cheng, Q; Jiang, X; Ma, J; Wu, Y; Zhang, M; Zhang, W1
Cheng, P; Li, X; Pei, S; Ye, Z; Zhang, L; Zheng, D; Zhu, L1
Hosseinzadeh, G; Hosseinzadeh, R; Khorsandi, K1
Évora, PRB; Faria, FM; Farina, JA; Oliveira, CC; Rosique, MJ; Rosique, RG1
Chung, YJ; Lee, BI; Park, CB; Suh, YS; Yu, K1
Cerqueira, B; Duong, TQ; Huang, L; Jiang, Z; Liu, Y; Lu, J1
Guo, B; Han, D; Hu, S; Liang, P; Su, C; Tie, X; Yan, X; Zhang, Q; Zhao, N; Zhuo, X; Zong, X1
Báo, SN; Bastos, AP; Damasceno, EAM; de Azevedo, RB; de Moura, LD; de Souza, PEN; Dos Santos, MSC; Gouvêa, AL; Paterno, LG; Veiga-Souza, FH1
Brauns, T; Gelfand, JA; Hamblin, MR; Huang, YY; Seed, PC; Wintner, A1
Bhurtel, S; Choi, DY; Katila, N; Neupane, S; Park, PH; Srivastav, S1
Martin, E; Monnier, V; Palandri, A; Rera, M; Russi, M; Tricoire, H1
Kopelman, R; Lee, CH; Tan, JWY; Wang, X1
Biondi, A; Cianci, S; Di Giorgio, A; Fagotti, A; Pacelli, F; Scambia, G; Tropea, A; Vizzielli, G1
Gao, Y; Li, S; Li, W; Shao, J; Shi, H; Velez de-la-Paz, OI; Wang, X; Yin, S; Yin, X1
Chen, C; Hu, Z; Jiang, Z; Zeng, L; Zhou, F1
Cantürk, NZ; Demir, Cİ; Güler, SA; Güneş, A; İşken, T; Kırnaz, S; Şimşek, T; Utkan, NZ1
Dang, ZS; Gui, WF; Xu, S; Zhao, YM1
Ishida, K; Kojima, S; Maeda, S; Nakamura, A; Saito, M; Soeda, Y; Takashima, A1
Carvalho, JS; Figueiredo-Godoi, LMA; Garcia, MT; Jorge, AOC; Junqueira, JC; Menezes, RT; Segundo, AG1
Bahadır, B; Can, M; Kefeli, A; Kılınç, F; Köktürk, F; Şen Tanrıkulu, C; Tanrıkulu, Y1
Meynaghizadeh-Zargar, R; Mohaddes, G; Rasta, SH; Sadigh-Eteghad, S; Salehpour, F1
Chibebe Junior, J; Fuchs, BB; Gilmore, MS; Hamblin, MR; Jorge, AO; Junqueira, JC; Mylonakis, E; Ribeiro, MS; Rice, LB; Sabino, CP; Tegos, GP1
Briolant, S; Desgrouas, C; Dormoi, J; Pradines, B2
Dormoi, J; Pradines, B1
Athanazio, DA; Azevedo, EC; Carvalho, MO; Chagas, UM; da Silva, CL; das Chagas, AD; dos Reis, MG; dos Santos, AC; Santos, CS; Soares, LM1
Alescio-Lautier, B; Fauvelle, F; Filali, M; Manrique, C; Maunoir-Regimbal, S; Paban, V1
Bourdais, A; Camadro, JM; Monnier, V; Palandri, A; Tricoire, H1
Ge, J; Guo, L; Wang, S; Wang, X; Wu, Y; Zhou, Y1
Carlson, GA; Friedman, T; Hyman, BT; Pitstick, R; Polydoro, M; Roe, A; Spires-Jones, TL1
Choi, YH; Kim, SG; Kim, TH; Shin, SY; Wu, H1
Aydogdu, I; Gedik, AH; Karatepe, HO; Kilic, E; Kilincaslan, H; Kucukkoc, M; Olgac, V1
Kovacic, P; Somanathan, R1
Limantsev, AV; Lychkova, AÉ; Pankrashin, VS; Puzikov, AM; Vasil'ev, IuV1
Eiferman, DS; Fenn, AM; Godbout, JP; Lifshitz, J; Moussa, DN; Muccigrosso, MM; Popovich, PG; Skendelas, JP1
Auchter, A; Barksdale, B; Gonzalez-Lima, F; Monfils, MH; Williams, J1
Abreu, Mda M; Almeida, FM; Correia, AT; Jatene, FB; Parra, ER; Pazetti, R; Pêgo-Fernandes, PM; Silva, LP; Vieira, RP1
Duong, TQ; Huang, S; Jiang, Z; Rodriguez, P; Shen, Q1
Dumbarton, TC; Farah, N; Lehmann, C; Maxan, A; Minor, S; Nantais, J; Zhou, J1
Berman, J; Im-Erbsin, R; Li, Q; Obaldia, N; Ohrt, C; Xie, L1
Bania, TC; Chu, J; Donovan, S; Hoffman, RS; Jang, DH; Nelson, LS1
Abdel-Kader, RM; Hamdi, N; Zakaria, A1
Huang, C; Jiang, B; Lu, X; Tong, L; Wang, J; Yao, W; Zhang, W1
Close, SP; Davidson, K; Deiana, S; Dietze, S; Goatman, EA; Goatman, K; Harrington, CR; Harrington, KA; Horsley, D; Magbagbeolu, M; Melis, V; Rickard, JE; Riedel, G; Schwab, K; Stamer, K; Storey, JM; Theuring, F; Wischik, CM; Zabke, C1
Aydogdu, I; Kilic, E; Kilincaslan, H; Koldas, M; Sarac, F; Terzi, EH1
Bozkurt, B; Dumlu, EG; Ergin, M; Kilic, M; Orhun, S; Ozkardes, AB; Tokac, M1
Abrao, J; Baker, GB; Balista, PA; Chaves, C; Dursun, SM; Evora, PR; Guimaraes, FS; Hallak, JE; Kandratavicius, L; Leite, JP; Maia-de-Oliveira, JP; Rodrigues, AJ; Wolf, DC1
Cadinu, D; Goll, P; Hochgräfe, K; Könen, S; Mandelkow, E; Mandelkow, EM; Matenia, D; Morellini, F; Petrova, O; Pickhardt, M; Sydow, A1
Boggs, RC; Duong, TQ; Huang, S; Long, JA; Manga, H; Shen, Q; Talley Watts, L1
Haouzi, P; Sonobe, T1
Di, Y; Fan, M; He, YL; Huang, X; Liu, SH; Wu, KW; Wu, LY; Zhao, T; Zhao, YQ; Zhu, LL1
Omata, Y; Sheik Mohideen, S; Tsuda, L; Yamasaki, Y; Yoshiike, Y1
Behfar, A; Dalén, M; Grinnemo, KH; Månsson-Broberg, A; Schiller, P; Seron, A; Sherman, W; Terzic, A1
Corrêa da Silva, JA; da Silva, LM; de Souza, MM; Holzmann, I; Steimbach, VM1
Binder, L; Bonnefoy, E; Buée, L; Chauderlier, A; Chouala, MS; Delattre, L; Galas, MC; Humez, S; Kayed, R; Lefebvre, B; Marciniak, E; Sultan, A; Tardivel, M; Violet, M1
Heidari, R; Martin, E; Monnier, V; Tricoire, H1
Baniene, R; Borutaite, V; Gulbinas, A; Jansen, E; Kincius, M; Kuliaviene, I; Kupcinskas, L; Trumbeckaite, S; Virketyte, S1
Liao, ZL; Qiu, YJ; Tan, YF; Yu, EY; Zhu, JP1
Antonio Julián, B; Carmen, GM; Fabio, CA; Francisco, C; Jesús, S; Leonor, PL; Yolanda, MB1
Kiboi, DM; Mumo, RM; Mwangi, VI; Ng'ang'a, ZW; Omar, SA; Ozwara, HS1
Barrett, EF; Barrett, JN; Nonner, D; Talbot, JD; Wicomb, K; Zhang, Z1
Li, L; Li, PJ; Lu, HL; Qin, L; Song, YJ; Yang, RL1
Asmar, S; Drancourt, M; Lépidi, H; Napez, C; Tian, RB1
Caramillo, EM; Echevarria, DJ1
Baldo, CF; Ceneviva, R; Evora, PR; Meirelles, RF; Viaro, F1
Elhawary, A; Mahdy, T; Mohamed, G1
Assreuy, J; Barja-Fidalgo, C; Fernandes, D; Heckert, BT; Lobo, AR; Nardi, GM; Pacheco, LK; Sordi, R; Villela, CG1
Gonzalez-Lima, F; John, JM; Lee, J; Rojas, JC1
Weinbroum, AA1
Behdad, A; Hosseinpour, M1
Hoffman, MR; Sha, Y; Shen, N; Wu, H; Xu, X; Ying, H; Zhou, L1
Bansal, PN; Entezari, V; Grinstaff, MW; Joshi, NS; Snyder, BD1
Hoffman, MR; Rieves, A; Sha, Y; Shen, N; Shu, Y; Wu, H; Xi, X; Ying, H; Zhou, L1
Garg, R; Gaur, V; Kumar, A; Kumar, P1
Jeziorczak, PM; Rawlings, AL; Vegunta, RK1
Bahremand, A; Dehpour, AR; Hedayat, T; Nasrabady, SE; Payandemehr, B; Rahimian, R; Ziai, P1
Deng, J; Duan, L; Huang, H; Kang, P; Pei, FX; Shen, B; Yan, D; Yang, J; Zhou, Z1
Huang, CC; Huang, HJ; Lee, YP; Wang, YF; Wong, TW; Yu, CK1
Caccamo, A; Medina, DX; Oddo, S1
Baran, TM; Biel, MA; Foster, TH; Giesselman, BR; Hu, R1
Aranha, AC; Corrêa, L; Orsini Machado de Sousa, SC; Simões, A; Sperandio, FF1
Aptekman, B; Ben-Abraham, R; Dolkart, O; Khoury, W; Khuri, W; Sotman, A; Tarashansky, M; Weinbroum, AA1
Foster, TH; Giesselman, BR; Haidaris, CG; Hupcher, SM; Mitra, S; Snell, SB1
Dhingra, D; Gilhotra, N1
Ashitate, Y; Frangioni, JV; Hutteman, M; Laurence, RG; Lee, BT; Lunsford, E; Ngo, LH; Oketokoun, R; Soo Choi, H1
Cai, S; França, CM; Mayer, MP; Prates, RA; Ribeiro, AC; Ribeiro, MS; Suzuki, LC; Yamada, AM1
Bil de Arce, VJ; Dai, T; Hamblin, MR; Tegos, GP1
Erçin, U; Eroğlu, HE; Kalaycı, MU; Koca, YS; Kubilay, D; Sancak, B; Soylu, A; Uğurluoğlu, C1
Lougheed, R; Turnbull, J1
Erpelding, TN; Jankovic, L; Kim, C; Wang, LV1
Albuquerque, AA; Capellini, VK; Celotto, AC; Evora, PR; Menardi, AC; Rodrigues, AJ; Viaro, F; Vicente, WV1
Castro e Silva, O; dos Santos, JS; Evora, PR; Rosique, IA; Rosique, MJ; Rosique, RG; Tirapelli, LF1
Audet, JN; Julien, JP; Soucy, G1
Gama, MF; Machado Filho, CD; Paschoal, FM; Pinhal, MA; Suarez, ER; Tardivo, JP; Theodoro, TR; Wagner, M1
Bittner, GD; Fan, JD; Robison, T; Spaeth, CS1
Bittner, GD; Britt, JM; Fan, JD; Gonzalez-Lima, F; Kane, JR; Keating, CP; Schallert, T; Spaeth, CS; Thayer, WP; Wilcott, RW; Winograd, JM; Zuzek, A1
Brunkwall, J; Fries, JW; Gawenda, M; Heckenkamp, J; Luebke, T; Schumacher, L; Theis, T; Thul, R1
Baumeister, R; Biernat, J; Fatouros, C; Koushika, SP; Mandelkow, E; Mandelkow, EM; Pir, GJ; Schmidt, E1
Agrawal, N; Aron, R; Finkbeiner, S; Glabe, C; Lau, A; Lotz, GP; Marsh, JL; Muchowski, PJ; Necula, M; Sontag, EM; Thompson, LM; Tran, A; Yang, G1
Bian, Y; Fan, X; Ji, P; Lan, J; Wang, Z1
Hosseinalipour, M; Kaka, G; Khoshmohabat, H; Panahi, F; Sadraie, SH; Shahram, E1
Dibaj, P; Göricke, B; Hanisch, UK; Kirchhoff, F; Le Meur, K; Neusch, C; Scheffel, J; Schomburg, ED; Steffens, H; Weishaupt, JH; Zschüntzsch, J1
Aldana, I; Bertani, S; Deharo, E; Garavito, G; Quiliano, M; Valentin, A1
Bouitbir, J; Chakfé, N; Charles, AL; Chenard, MP; Collange, O; Diemunsch, P; Geny, B; Piquard, F; Thaveau, F; Zoll, J1
Akoury, E; Biernat, J; Gajda, M; Mandelkow, E; Pickhardt, M; Zweckstetter, M1
Bjertnaes, LJ; Evgenov, NV; Evgenov, OV; Mollnes, TE1
Ak, D; Cetin, A; Cetin, M; Duran, B; Guvenal, T; Yanar, O1
Cetin, A; Cetin, M; Demirkoprulu, N; Duran, B; Erden, O; Guvenal, T1
Barennes, H; Boudat, AM; Idle, JR; Nagot, N; Valea, I1
Barlas, M; Bingol-Kologlu, M; Cedden, F; Denli, O; Hasçiçek, C; Ozdamar, S; Yagmurlu, A1
Fedorovich, AA; Krivoruchko, IA1
Liu, L; Lohman, RJ; Morris, M; O'Brien, TJ1
Brenner, M; Cerussi, AE; Duke, A; El-Abaddi, N; Lee, J; Tromberg, BJ1
Boda, C; Bouteille, B; Breton, JC; Courtioux, B; Enanga, B1
Bisland, SK; Burch, S; Chien, C; Wilson, BC1
Gonzalez-Lima, F; Rojas, JC; Zhang, X1
Bayraktar, N; Demirbilek, S; Ersoy, MO; Karadag, N; Karaman, A; Sizanli, E; Turkmen, E1
Kulkarni, SK; Padi, SV; Patil, CS; Singh, VP1
Alagol, H; Dinc, S; Karaca, S; Kuru, B; Oz, M; Ozaslan, C; Renda, N; Ustun, H1
Kopeć, T; Szczepański, M; Szyfter, W; Zeromski, J1
Fisher, RS; Kraus, AC; Oommen, J1
Aksu, B; Aydin, S; Ayvaz, S; Durmus-Altun, G; Gurcan, S; Inan, M; Kanter, M; Oz Puyan, F; Pul, M; Uzun, H1
Basu, S; Miclescu, A; Wiklund, L1
Aydogdu, N; Basaran, UN; Dokmeci, D; Inan, M; Turan, N; Yalcin, O1
Basu, S; Miclescu, A; Ronquist, G; Sharma, HS; Wiklund, L; Wiklund, P1
Wang, HL; Wang, Z; Yu, CH; Yu, XZ; Zhu, HD1
Goosey, JD; Kinoshita, JH; Zigler, JS1
Chen, SJ; Wu, CC; Yen, MH1
Descombes, JJ; Laubie, M; Mennecier, P; Porro de Bailliencourt, J; Simonet, S; Verbeuren, TJ1
Fujihara, T; Nagano, T; Nakamura, M; Shirasawa, E1
Blower, PJ; Costa, DC; Ell, PJ; Link, EM; Lui, D; Spittle, MF1
Breslin, E; Cawley, T; Docherty, JR; Geraghty, J; Osborne, H1
Sun, W; Wainwright, CL1
Hosokawa, M; Kamata, K1
Inoue, T; Mashimo, T; Shibata, M; Shibuta, S; Yoshiya, I1
Rao, JP; Robert, FS2
Ben-Abraham, R; Galili, Y; Iaina, A; Klausner, J; Kluger, Y; Marmur, S; Peer, G; Rabau, M; Soffer, D; Szold, O; Volman, Y; Weinbroum, A1
Bauer, EP; Binz, K; Klövekorn, WP; Podzuweit, T; Reuthebuch, O; Roth, M; Thomas, S1
Graf, E; Hochhauser, E; Karchevsky, E; Kluger, Y; Rudick, V; Vidne, BA; Weinbroum, AA1
Bernsen, MR; Bosman, F; Dullens, HF; Franssen, O; Hennink, WE; Slootweg, PJ; van Es, RJ1
Beck, G; Genze, F; Orth, K; Rück, A1
Kluger, Y; Rudick, V; Shapira, I; Weinbroum, AA1
Bjertnaes, LJ; Evgenov, OV; Sager, G1
Abu-Abid, S; Ben-Avraham, R; Jeroukhimov, I; Kluger, Y; Michowitz, M; Weinbroum, A1
Biel, MA; Jones, JW; Teichert, MC; Usacheva, MN1
Cameron, RB; Kasten, BL; Watts, JC1
Brigman, J; Finlayson, B1
Berg, W; Hartmann, U; Hensel, K; Hesse, A; Lange, U; Schneider, HJ1
Olsson, CA; Selikowitz, SM1
Kamijo, T; Kido, H; Miwa, A; Nakamura, F; Sugimoto, T; Tomaru, T; Uchida, Y1
Maronpot, RR1
Adams, JR; Bergan, JJ; Binder, PS; Cerra, FB; Eilert, JB; Heiskell, CA1

Reviews

3 review(s) available for methylene blue and Disease Models, Animal

ArticleYear
Toxicity of imine-iminium dyes and pigments: electron transfer, radicals, oxidative stress and other physiological effects.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:8

    Topics: Animals; Benzophenoneidum; Coloring Agents; Disease Models, Animal; Electron Transport; Humans; Imines; Indoles; Isoindoles; Methylene Blue; Oxidative Stress; Pheophytins; Pyocyanine; Reactive Oxygen Species; Rhodamines; Rosaniline Dyes; Trityl Compounds

2014
Alzheimer's disease in the zebrafish: where can we take it?
    Behavioural pharmacology, 2017, Volume: 28, Issue:2 and 3-Sp

    Topics: Alzheimer Disease; Animals; Dementia; Disease Models, Animal; Donepezil; Humans; Indans; Memantine; Methylene Blue; Piperidines; Rodentia; Species Specificity; Zebrafish

2017
Neuro- and cardioprotective effects of blockade of nitric oxide action by administration of methylene blue.
    Annals of the New York Academy of Sciences, 2007, Volume: 1122

    Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Creatine Kinase, MB Form; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; History, 19th Century; Methylene Blue; Myocardial Ischemia; Myocardial Reperfusion; Nerve Growth Factors; Nitric Oxide; Random Allocation; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Survival Analysis; Swine; Time Factors; Troponin I

2007

Trials

1 trial(s) available for methylene blue and Disease Models, Animal

ArticleYear
Chronic oral methylene blue treatment in a rat model of focal cerebral ischemia/reperfusion.
    Brain research, 2018, Jan-01, Volume: 1678

    Topics: Administration, Oral; Analysis of Variance; Animals; Disease Models, Animal; Double-Blind Method; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Methylene Blue; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion; Sensory Gating; Silver Staining; Spin Labels

2018

Other Studies

169 other study(ies) available for methylene blue and Disease Models, Animal

ArticleYear
Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-trifluoromethyl Pyrido[1,2- a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria.
    Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2

    Topics: Animals; Antimalarials; Benzimidazoles; Disease Models, Animal; Drug Design; ERG1 Potassium Channel; Half-Life; Hemeproteins; Life Cycle Stages; Malaria; Mice; Mice, Inbred C57BL; Plasmodium; Structure-Activity Relationship; Survival Rate

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Intradermal methylene blue administration on the progression of burn injuries.
    Journal of wound care, 2021, Sep-02, Volume: 30, Issue:Sup9a

    Topics: Animals; Burns; Disease Models, Animal; Male; Methylene Blue; Necrosis; Rats; Rats, Wistar

2021
Pretreatment with Methylene Blue Protects Against Acute Seizure and Oxidative Stress in a Kainic Acid-Induced Status Epilepticus Model.
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Oct-10, Volume: 27

    Topics: Amygdala; Animals; Antioxidants; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Glutamic Acid; Hippocampus; Humans; Kainic Acid; Male; Methylene Blue; Mice; Neuroprotective Agents; Oxidative Stress; Status Epilepticus

2021
Methylene blue and carbon nanoparticles had no significant adverse effects on the survival and function of lymph nodes after non-vascularized transplantation in a mouse model.
    Transplant immunology, 2022, Volume: 72

    Topics: Animals; Carbon; Disease Models, Animal; Iatrogenic Disease; Lymph Nodes; Methylene Blue; Mice; Nanoparticles

2022
Methylene Blue to Neonatal Septic Shock treatment in neonate pigs
    Clinics (Sao Paulo, Brazil), 2022, Volume: 77

    Topics: Animals; Disease Models, Animal; Lactic Acid; Male; Methylene Blue; Neonatal Sepsis; Sepsis; Shock, Septic; Swine

2022
Neuroprotective effects of methylene blue in streptozotocin-induced model of Alzheimer's disease.
    Brain research, 2023, 04-15, Volume: 1805

    Topics: Alzheimer Disease; Animals; Disease Models, Animal; Hippocampus; Maze Learning; Methylene Blue; Neuroprotective Agents; Rats; Streptozocin

2023
Human Tau Aggregates Are Permissive to Protein Synthesis-Dependent Memory in
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023, 04-19, Volume: 43, Issue:16

    Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Drosophila; Humans; Memory Disorders; Methylene Blue; tau Proteins; Tauopathies

2023
Involvement of l-arginine-nitric oxide pathway in the antidepressant and memory promoting effects of morin in mice.
    Drug development research, 2019, Volume: 80, Issue:8

    Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Depression; Disease Models, Animal; Flavonoids; Injections, Intraperitoneal; Male; Memory; Memory and Learning Tests; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Signal Transduction; Swimming

2019
Mechanisms of Anticholinesterase Interference with Tau Aggregation Inhibitor Activity in a Tau-Transgenic Mouse Model.
    Current Alzheimer research, 2020, Volume: 17, Issue:3

    Topics: Alzheimer Disease; Animals; Brain; Cholinesterase Inhibitors; Disease Models, Animal; Drug Interactions; Methylene Blue; Mice; Mice, Transgenic; Protein Aggregates; Rivastigmine; tau Proteins

2020
Effects of NO/cGMP inhibitors in a rat model of anaphylactoid shock.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2020, Volume: 53, Issue:3

    Topics: Anaphylaxis; Animals; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Indigo Carmine; Male; Methylene Blue; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar

2020
Effect of Methylene Blue on a Porcine Model of Amlodipine Toxicity.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2020, Volume: 16, Issue:4

    Topics: Amlodipine; Animals; Antidotes; Cardiotoxicity; Cardiovascular Diseases; Cardiovascular System; Disease Models, Animal; Hemodynamics; Methylene Blue; Norepinephrine; Sus scrofa; Time Factors

2020
Methylene blue post-treatment improves hypoxia-ischemic recovery in a neonatal rat model.
    Neurochemistry international, 2020, Volume: 139

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Female; Hypoxia-Ischemia, Brain; Male; Methylene Blue; Rats; Rats, Sprague-Dawley; Recovery of Function; Treatment Outcome

2020
Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo.
    Parasites & vectors, 2020, Jul-20, Volume: 13, Issue:1

    Topics: Aminoquinolines; Animals; Antimalarials; Artesunate; Babesia bovis; Babesia microti; Babesiosis; Disease Models, Animal; Drug Combinations; In Vitro Techniques; Lumefantrine; Mefloquine; Methylene Blue; Mice; Mice, Inbred BALB C

2020
Methylene blue promotes survival and GAP-43 expression of retinal ganglion cells after optic nerve transection.
    Life sciences, 2020, Dec-01, Volume: 262

    Topics: Animals; Axons; Cell Survival; Cricetinae; Disease Models, Animal; Female; GAP-43 Protein; Intravitreal Injections; Methylene Blue; Nerve Regeneration; Neuroprotective Agents; Optic Nerve; Optic Nerve Injuries; Retinal Ganglion Cells; Time Factors

2020
Protective effect of methylene blue against copper oxide nanoparticle-induced neurobehavioral toxicity.
    Behavioural brain research, 2021, 02-01, Volume: 398

    Topics: Aldehyde Dehydrogenase, Mitochondrial; Animals; Apoptosis; Behavior, Animal; Brain; Copper; Disease Models, Animal; Enzyme Inhibitors; Glutamate Dehydrogenase; Male; Methylene Blue; Nanoparticles; Neurotoxicity Syndromes; Oxidative Stress; Rats

2021
Efficacy of methylene blue in a murine model of amlodipine overdose.
    The American journal of emergency medicine, 2021, Volume: 45

    Topics: Amlodipine; Animals; Cardiotoxicity; Disease Models, Animal; Drug Overdose; Methylene Blue; Mice; Mice, Inbred C57BL; Stroke Volume; Ventricular Function, Left

2021
Methylene blue is a potent and broad-spectrum inhibitor against Zika virus
    Emerging microbes & infections, 2020, Volume: 9, Issue:1

    Topics: A549 Cells; Administration, Oral; Animals; Antiviral Agents; Cell Line; Dengue Virus; Disease Models, Animal; Gene Expression Regulation, Viral; Humans; Male; Methylene Blue; Mice; Protease Inhibitors; Protein Binding; RNA Helicases; Serine Endopeptidases; Viral Load; Viral Nonstructural Proteins; Viral Proteins; Virus Internalization; Zika Virus; Zika Virus Infection

2020
Methylene blue induces an analgesic effect by significantly decreasing neural firing rates and improves pain behaviors in rats.
    Biochemical and biophysical research communications, 2021, 02-19, Volume: 541

    Topics: Action Potentials; Analgesics; Animals; Coloring Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Femoral Nerve; Hindlimb; Lidocaine; Male; Methylene Blue; Neural Inhibition; Neurons; Pain; Rats; Rats, Sprague-Dawley

2021
Methylene blue and photobiomodulation recover cognitive impairment in hepatic encephalopathy through different effects on cytochrome c-oxidase.
    Behavioural brain research, 2021, 04-09, Volume: 403

    Topics: Animals; Cognitive Dysfunction; Disease Models, Animal; Electron Transport Complex IV; Enzyme Inhibitors; Hepatic Encephalopathy; Hippocampus; Low-Level Light Therapy; Male; Methylene Blue; Neostriatum; Prefrontal Cortex; Rats, Wistar

2021
Effect of Methylene Blue on White Matter Injury after Ischemic Stroke.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Animals; Apoptosis; Basal Ganglia; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Hippocampus; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Methylene Blue; Mice; Motor Activity; Myelin Sheath; Neurons; Rats, Sprague-Dawley; Thrombosis; White Matter

2021
Intravitreally Injected Methylene Blue Protects Retina against Acute Ocular Hypertension in Rats.
    Current eye research, 2022, Volume: 47, Issue:1

    Topics: Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Electroretinography; Enzyme Inhibitors; Intraocular Pressure; Intravitreal Injections; Male; Methylene Blue; Ocular Hypertension; Rats; Retina; Tomography, Optical Coherence

2022
Graphene oxide-methylene blue nanocomposite in photodynamic therapy of human breast cancer.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:9

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Female; Graphite; Humans; Methylene Blue; Mice; Nanocomposites; Oxides; Photochemotherapy; Photosensitizing Agents; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction; Xenograft Model Antitumor Assays

2018
Methylene blue reduces progression of burn and increases skin survival in an experimental rat model.
    Burns : journal of the International Society for Burn Injuries, 2017, Volume: 43, Issue:8

    Topics: Animals; Antioxidants; Burns; Disease Models, Animal; Disease Progression; Injections, Intraperitoneal; Male; Malondialdehyde; Methylene Blue; Necrosis; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Skin; Wound Healing

2017
Shedding Light on Alzheimer's β-Amyloidosis: Photosensitized Methylene Blue Inhibits Self-Assembly of β-Amyloid Peptides and Disintegrates Their Aggregates.
    Scientific reports, 2017, 08-08, Volume: 7, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Animals; Brain; Disease Models, Animal; Drosophila melanogaster; Humans; Light; Locomotion; Methylene Blue; Neuromuscular Junction; Neuroprotective Agents; Nootropic Agents; Oxidation-Reduction; Peptide Fragments; Photochemotherapy; Photosensitizing Agents; Protein Aggregates; Singlet Oxygen

2017
After Treatment with Methylene Blue is Effective against Delayed Encephalopathy after Acute Carbon Monoxide Poisoning.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Antidotes; Antioxidants; Apoptosis; Behavior, Animal; Brain Diseases; CA1 Region, Hippocampal; Carbon Monoxide Poisoning; Cognition; Disease Models, Animal; Inflammation Mediators; Interleukin-1beta; Male; Maze Learning; Methylene Blue; Mitochondria; Mitochondrial Dynamics; Neurons; Oxidative Stress; Rats, Sprague-Dawley; Spatial Learning; Time Factors; Tumor Necrosis Factor-alpha

2018
Nanographene oxide-methylene blue as phototherapies platform for breast tumor ablation and metastasis prevention in a syngeneic orthotopic murine model.
    Journal of nanobiotechnology, 2018, Jan-30, Volume: 16, Issue:1

    Topics: Ablation Techniques; Animals; Apoptosis; Body Weight; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Female; Graphite; Immunohistochemistry; Luminescence; Mammary Neoplasms, Animal; Methylene Blue; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasm Metastasis; NIH 3T3 Cells; Photochemotherapy; Phototherapy; Reactive Oxygen Species; Tumor Burden

2018
Antimicrobial photodynamic therapy mediated by methylene blue and potassium iodide to treat urinary tract infection in a female rat model.
    Scientific reports, 2018, 05-08, Volume: 8, Issue:1

    Topics: Animals; Anti-Infective Agents; Disease Models, Animal; Female; Humans; Methylene Blue; Photochemotherapy; Photosensitizing Agents; Potassium Iodide; Rats; Urinary Tract Infections; Uropathogenic Escherichia coli

2018
Methylene blue protects dopaminergic neurons against MPTP-induced neurotoxicity by upregulating brain-derived neurotrophic factor.
    Annals of the New York Academy of Sciences, 2018, Volume: 1431, Issue:1

    Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dopaminergic Neurons; Male; Methylene Blue; Mice; MPTP Poisoning; Neuroprotective Agents; Phosphorylation; Signal Transduction; Tyrosine 3-Monooxygenase; Up-Regulation

2018
Identification of cardioprotective drugs by medium-scale
    Disease models & mechanisms, 2018, 07-20, Volume: 11, Issue:7

    Topics: Actins; Animals; Cardiotonic Agents; Disease Models, Animal; Drosophila melanogaster; Drug Evaluation, Preclinical; Frataxin; Friedreich Ataxia; Iron-Binding Proteins; Methylene Blue; Microtubules; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Myosins; Paclitaxel; Reproducibility of Results; Sarcomeres; Small Molecule Libraries

2018
Transient Triplet Differential (TTD) Method for Background Free Photoacoustic Imaging.
    Scientific reports, 2018, 06-18, Volume: 8, Issue:1

    Topics: Animals; Disease Models, Animal; Humans; Imaging, Three-Dimensional; Methylene Blue; Nanoparticles; Neoplasms; Photoacoustic Techniques; Reproducibility of Results; Signal Processing, Computer-Assisted; Signal-To-Noise Ratio; Time-Lapse Imaging

2018
A novel HIPEC technique using hybrid CO
    Updates in surgery, 2018, Volume: 70, Issue:4

    Topics: Abdominal Cavity; Absorption, Physiological; Animals; Antineoplastic Agents; Carbon Dioxide; Chemotherapy, Cancer, Regional Perfusion; Disease Models, Animal; Female; Hyperthermia, Induced; Methylene Blue; Peritoneal Neoplasms; Pressure; Swine

2018
Methylene blue exerts rapid neuroprotective effects on lipopolysaccharide-induced behavioral deficits in mice.
    Behavioural brain research, 2019, 01-01, Volume: 356

    Topics: Animals; Behavior, Animal; Depressive Disorder; Disease Models, Animal; Lipopolysaccharides; Male; Memory Disorders; Methylene Blue; Mice; Neuroprotective Agents

2019
Methylene blue offers neuroprotection after intracerebral hemorrhage in rats through the PI3K/Akt/GSK3β signaling pathway.
    Journal of cellular physiology, 2019, Volume: 234, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Blood-Brain Barrier; Brain; Brain Edema; Capillary Permeability; Cerebral Hemorrhage; Cytokines; Disease Models, Animal; Encephalitis; Glycogen Synthase Kinase 3 beta; Male; Methylene Blue; Microglia; Neurons; Neuroprotective Agents; Neutrophil Infiltration; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction

2019
Cutaneous adverse effects of methylene blue in an animal skin-flap model.
    Acta chirurgica Belgica, 2020, Volume: 120, Issue:3

    Topics: Animals; Disease Models, Animal; Graft Survival; Male; Methylene Blue; Rats; Rats, Wistar; Skin; Skin Transplantation; Surgical Flaps

2020
In Vitro and in Vivo Effect of MAPK Signal Transduction Pathway Inhibitors on Echinococcus multilocularis.
    The Journal of parasitology, 2019, Volume: 105, Issue:1

    Topics: Albendazole; Animals; Anthelmintics; Benzamides; Body Weight; Cell Line; Disease Models, Animal; Echinococcosis; Echinococcus multilocularis; Female; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Inhibitory Concentration 50; Methylene Blue; Mice; Mice, Inbred BALB C; Protein Array Analysis; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Toluene

2019
Methylene Blue Inhibits Formation of Tau Fibrils but not of Granular Tau Oligomers: A Plausible Key to Understanding Failure of a Clinical Trial for Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 68, Issue:4

    Topics: Alzheimer Disease; Animals; Disease Models, Animal; Methylene Blue; Mice; Neurofibrillary Tangles; Phosphorylation; tau Proteins

2019
Exploring the Galleria mellonella model to study antifungal photodynamic therapy.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 27

    Topics: Animals; Candida albicans; Candidiasis; Disease Models, Animal; Larva; Lasers, Semiconductor; Methylene Blue; Moths; Photochemotherapy; Photosensitizing Agents

2019
The protective and anti-inflammatory effect of methylene blue in corrosive esophageal burns: An experimental study.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2019, Volume: 25, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Burns, Chemical; Caustics; Disease Models, Animal; Enzyme Inhibitors; Esophageal Stenosis; Esophagus; Hydroxyproline; Methylene Blue; Random Allocation; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2019
Effects of transcranial photobiomodulation and methylene blue on biochemical and behavioral profiles in mice stress model.
    Lasers in medical science, 2020, Volume: 35, Issue:3

    Topics: Animals; Antioxidants; Behavior, Animal; Brain; Disease Models, Animal; Glutathione Peroxidase; Low-Level Light Therapy; Male; Maze Learning; Memory; Methylene Blue; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Recognition, Psychology; Skull; Superoxide Dismutase

2020
Photodynamic and antibiotic therapy impair the pathogenesis of Enterococcus faecium in a whole animal insect model.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Enterococcus faecium; Gram-Positive Bacterial Infections; Methylene Blue; Moths; Photochemotherapy; Photosensitizing Agents

2013
Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model.
    Malaria journal, 2013, Apr-15, Volume: 12

    Topics: Animals; Antimalarials; Atorvastatin; Disease Models, Animal; Drug Synergism; Female; Heptanoic Acids; Kaplan-Meier Estimate; Malaria, Cerebral; Methylene Blue; Mice; Mice, Inbred C57BL; Parasitemia; Pyrroles

2013
Efficacy of proveblue (methylene blue) in an experimental cerebral malaria murine model.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Female; Malaria, Cerebral; Methylene Blue; Mice; Mice, Inbred C57BL; Plasmodium berghei

2013
Dose responses of proveblue methylene blue in an experimental murine cerebral malaria model.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:8

    Topics: Animals; Antimalarials; Artemisinins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Erythrocytes; Female; Kaplan-Meier Estimate; Malaria, Cerebral; Methylene Blue; Mice; Mice, Inbred C57BL; Plasmodium berghei; Time Factors; Treatment Outcome

2013
Ionic imbalance and lack of effect of adjuvant treatment with methylene blue in the hamster model of leptospirosis.
    Memorias do Instituto Oswaldo Cruz, 2013, Volume: 108, Issue:4

    Topics: Animals; Cricetinae; Disease Models, Animal; Guanylate Cyclase; Ion Channels; Leptospirosis; Magnesium; Methylene Blue; Nitrogen Oxides; Potassium; Receptors, Cytoplasmic and Nuclear; Sodium; Soluble Guanylyl Cyclase

2013
Therapeutic and preventive effects of methylene blue on Alzheimer's disease pathology in a transgenic mouse model.
    Neuropharmacology, 2014, Volume: 76 Pt A

    Topics: Administration, Oral; Alanine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning; Cerebral Cortex; Discrimination, Psychological; Disease Models, Animal; Hippocampus; Injections, Intraperitoneal; Lactic Acid; Male; Methylene Blue; Mice; Mice, Transgenic; Mitochondria; Motor Activity; Nesting Behavior; Neuroprotective Agents

2014
Methylene blue rescues heart defects in a Drosophila model of Friedreich's ataxia.
    Human molecular genetics, 2014, Feb-15, Volume: 23, Issue:4

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Drug Evaluation, Preclinical; Frataxin; Friedreich Ataxia; Gene Knockdown Techniques; Humans; Iron-Binding Proteins; Male; Methylene Blue; RNA Interference; Ubiquinone

2014
A novel method for efficient delivery of stem cells to the ischemic brain.
    Stem cell research & therapy, 2013, Volume: 4, Issue:5

    Topics: Animals; Carotid Artery, Internal; Disease Models, Animal; Female; Fluorescent Dyes; Humans; Infarction, Middle Cerebral Artery; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Methylene Blue; Rats; Rats, Sprague-Dawley; Stroke

2013
Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy.
    Neuroscience letters, 2014, Mar-06, Volume: 562

    Topics: Amyloid beta-Peptides; Animals; Disease Models, Animal; Female; Male; Methylene Blue; Mice; Mice, 129 Strain; Mice, Transgenic; Neurofibrillary Tangles; tau Proteins; Tauopathies

2014
SIRT1 activation by methylene blue, a repurposed drug, leads to AMPK-mediated inhibition of steatosis and steatohepatitis.
    European journal of pharmacology, 2014, Mar-15, Volume: 727

    Topics: Administration, Oral; AMP-Activated Protein Kinases; Animals; Disease Models, Animal; DNA, Mitochondrial; Dose-Response Relationship, Drug; Drug Repositioning; Energy Metabolism; Enzyme Activation; Enzyme Activators; Fatty Liver; Hep G2 Cells; Humans; Lipid Metabolism; Liver; Male; Methylene Blue; Mice, Inbred C57BL; Mitochondria, Liver; Mitochondrial Turnover; NAD; Rats; RNA Interference; Sirtuin 1; Time Factors; Transfection

2014
Beneficial effects of methylene blue on the acute phase of corrosive esophageal burn in rats.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2015, Volume: 25, Issue:3

    Topics: Animals; Burns, Chemical; Catalase; Caustics; Disease Models, Animal; Esophageal Stenosis; Esophagitis; Male; Methylene Blue; Oxidants; Oxidative Stress; Rats, Sprague-Dawley; Superoxide Dismutase

2015
[Gastroesophageal reflux disease model].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2013, Issue:9

    Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Esophagus; Female; Gastroesophageal Reflux; Humans; Male; Methylene Blue; Rats

2013
Methylene blue attenuates traumatic brain injury-associated neuroinflammation and acute depressive-like behavior in mice.
    Journal of neurotrauma, 2015, Jan-15, Volume: 32, Issue:2

    Topics: Animals; Behavior, Animal; Brain Edema; Brain Injuries; Depression; Disease Models, Animal; Inflammation; Interleukin-10; Interleukin-1beta; Methylene Blue; Mice; Microglia; Tumor Necrosis Factor-alpha

2015
Therapeutic benefits of methylene blue on cognitive impairment during chronic cerebral hypoperfusion.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 42 Suppl 4

    Topics: Analysis of Variance; Animals; Association Learning; Cognitive Dysfunction; Coronary Occlusion; Disease Models, Animal; Enzyme Inhibitors; Exploratory Behavior; Locomotion; Male; Methylene Blue; Motor Activity; Odorants; Rats; Rats, Long-Evans; Recognition, Psychology

2014
Methylene blue attenuates ischemia--reperfusion injury in lung transplantation.
    The Journal of surgical research, 2014, Volume: 192, Issue:2

    Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Cold Ischemia; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Female; Hemorrhage; Lung Transplantation; Methylene Blue; Nitric Oxide; Oxygen; Partial Pressure; Pulmonary Edema; Rats, Sprague-Dawley; Reperfusion Injury; Sodium Chloride; Uric Acid

2014
Methylene blue treatment delays progression of perfusion-diffusion mismatch to infarct in permanent ischemic stroke.
    Brain research, 2014, Nov-07, Volume: 1588

    Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Methylene Blue; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley; Treatment Outcome

2014
Impact of methylene blue in addition to norepinephrine on the intestinal microcirculation in experimental septic shock.
    Clinical hemorheology and microcirculation, 2014, Volume: 58, Issue:1

    Topics: Animals; Cell Adhesion; Disease Models, Animal; Endothelium, Vascular; Endotoxins; Hemodynamics; Intestines; Leukocytes; Lipopolysaccharides; Methylene Blue; Microcirculation; Norepinephrine; Pressure; Rats; Rats, Inbred Lew; Shock, Septic

2014
Efficacy of intravenous methylene blue, intravenous artesunate, and their combination in preclinical models of malaria.
    Malaria journal, 2014, Oct-21, Volume: 13

    Topics: Administration, Intravenous; Animals; Antimalarials; Aotidae; Artemisinins; Artesunate; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Macaca mulatta; Malaria; Male; Methylene Blue; Plasmodium berghei; Plasmodium cynomolgi; Rats; Rats, Sprague-Dawley; Treatment Outcome

2014
Efficacy of methylene blue in an experimental model of calcium channel blocker-induced shock.
    Annals of emergency medicine, 2015, Volume: 65, Issue:4

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Disease Models, Animal; Free Radical Scavengers; Guanylate Cyclase; Methylene Blue; Rats, Sprague-Dawley; Shock

2015
Methylene Blue Improves Brain Mitochondrial ABAD Functions and Decreases Aβ in a Neuroinflammatory Alzheimer's Disease Mouse Model.
    Molecular neurobiology, 2016, Volume: 53, Issue:2

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Alcohol Dehydrogenase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cell Survival; Cerebral Cortex; Disease Models, Animal; Estradiol; Inflammation; Lipopolysaccharides; Male; Methylene Blue; Mice; Mitochondria; Oxidative Stress; Reactive Oxygen Species

2016
Methylene Blue Attenuates iNOS Induction Through Suppression of Transcriptional Factor Binding Amid iNOS mRNA Transcription.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:8

    Topics: Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Endotoxemia; Gene Expression Regulation; Interferon-gamma; Lipopolysaccharides; Macrophages; Male; Methylene Blue; Mice; Nitric Oxide Synthase Type II; Protein Binding; Transcription Factors

2015
Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models.
    Behavioural pharmacology, 2015, Volume: 26, Issue:4

    Topics: Animals; Brain; Cohort Studies; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Learning Disabilities; Maze Learning; Methylene Blue; Mice, Transgenic; Motor Activity; Neurons; Neuroprotective Agents; Oxidation-Reduction; Problem Solving; Random Allocation; Tauopathies

2015
Methylene blue attenuates renal ischemia-reperfusion injury in rats.
    Journal of pediatric surgery, 2015, Volume: 50, Issue:6

    Topics: Animals; Biomarkers; Disease Models, Animal; Enzyme Inhibitors; Kidney; Kidney Diseases; Male; Methylene Blue; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Serum Albumin; Serum Albumin, Human

2015
Methylene blue as an antioxidant agent in experimentally-induced injury in rat liver.
    Bratislavske lekarske listy, 2015, Volume: 116, Issue:3

    Topics: Animals; Antioxidants; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Coloring Agents; Disease Models, Animal; Lipid Peroxidation; Liver; Male; Methylene Blue; Random Allocation; Rats; Wounds, Penetrating

2015
Effects of nitric oxide-related compounds in the acute ketamine animal model of schizophrenia.
    BMC neuroscience, 2015, Mar-07, Volume: 16

    Topics: Acute Disease; Animals; Antipsychotic Agents; Cognition Disorders; Dietary Sucrose; Disease Models, Animal; Exploratory Behavior; Male; Methylene Blue; Motor Activity; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; Rats, Wistar; Recognition, Psychology; Schizophrenia; Schizophrenic Psychology; Taste Perception; Treatment Outcome

2015
Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.
    Acta neuropathologica communications, 2015, May-10, Volume: 3

    Topics: Animals; Behavior, Animal; Cognition; Cognition Disorders; Disease Models, Animal; Enzyme Inhibitors; Humans; Maze Learning; Memory; Methylene Blue; Mice; Mice, Inbred C57BL; Mice, Transgenic; tau Proteins; Tauopathies; Time Factors; Treatment Outcome

2015
Delayed Methylene Blue Improves Lesion Volume, Multi-Parametric Quantitative Magnetic Resonance Imaging Measurements, and Behavioral Outcome after Traumatic Brain Injury.
    Journal of neurotrauma, 2016, Jan-15, Volume: 33, Issue:2

    Topics: Animals; Behavior, Animal; Brain Injuries; Disease Models, Animal; Enzyme Inhibitors; Forelimb; Magnetic Resonance Imaging; Male; Methylene Blue; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Somatosensory Cortex

2016
H2S induced coma and cardiogenic shock in the rat: Effects of phenothiazinium chromophores.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:6

    Topics: Animals; Antidotes; Azure Stains; Biotransformation; Cardiac Output; Cardiotonic Agents; Coma; Disease Models, Animal; Hydrogen Sulfide; Male; Methylene Blue; Phenothiazines; Rats, Sprague-Dawley; Shock, Cardiogenic; Structure-Activity Relationship; Sulfides; Time Factors; Ventricular Function, Left; Ventricular Pressure

2015
Methylene Blue Reduces Acute Cerebral Ischemic Injury via the Induction of Mitophagy.
    Molecular medicine (Cambridge, Mass.), 2015, May-19, Volume: 21

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Glucose; Humans; Infarction, Middle Cerebral Artery; Male; Membrane Potential, Mitochondrial; Methylene Blue; Mitophagy; Necrosis; Neuroprotective Agents; Oxygen; Rats; Reperfusion Injury; Stroke

2015
Nontoxic singlet oxygen generator as a therapeutic candidate for treating tauopathies.
    Scientific reports, 2015, Jun-01, Volume: 5

    Topics: Animals; Animals, Genetically Modified; Autophagy; Behavior, Animal; Disease Models, Animal; Drosophila; Female; Humans; Male; Methylene Blue; Oxidative Stress; Singlet Oxygen; Solubility; tau Proteins; Tauopathies

2015
Percutaneous Fluoroscopic-Guided Endomyocardial Delivery in an Experimental Model of Left Ventricular Assist Device Support.
    Journal of cardiovascular translational research, 2015, Volume: 8, Issue:6

    Topics: Animals; Cardiac Catheterization; Disease Models, Animal; Fluoroscopy; Heart Failure; Heart Ventricles; Heart-Assist Devices; Injections; Methylene Blue; Myocardium; Radiography, Interventional; Swine

2015
Antidepressant-like effect of quercetin in bulbectomized mice and involvement of the antioxidant defenses, and the glutamatergic and oxidonitrergic pathways.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 136

    Topics: Animals; Antidepressive Agents; Antioxidants; Arginine; Behavior, Animal; Disease Models, Animal; Drug Synergism; Fluoxetine; Hippocampus; Indazoles; Male; Methylene Blue; Mice; N-Methylaspartate; Olfactory Bulb; Oxidative Stress; Quercetin; Signal Transduction; Sildenafil Citrate

2015
Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo.
    Neurobiology of disease, 2015, Volume: 82

    Topics: Animals; Cell Death; Cell Nucleus; Cytoplasm; Disease Models, Animal; DNA Breaks; Female; Fever; Hippocampus; Humans; Methylene Blue; Mice, Transgenic; Neurons; Neuroprotective Agents; Oxidative Stress; Protein Multimerization; RNA; tau Proteins; Tauopathies

2015
Methylene Blue Partially Rescues Heart Defects in a Drosophila Model of Huntington's Disease.
    Journal of Huntington's disease, 2015, Volume: 4, Issue:2

    Topics: Animals; Disease Models, Animal; Drosophila; Drosophila Proteins; Heart Defects, Congenital; Huntingtin Protein; Huntington Disease; Methylene Blue; Microtubule-Associated Proteins; Neuroglia; Neurons

2015
Methylene blue attenuates mitochondrial dysfunction of rat kidney during experimental acute pancreatitis.
    Journal of digestive diseases, 2016, Volume: 17, Issue:3

    Topics: Acute Disease; Amylases; Animals; Biomarkers; Disease Models, Animal; Drug Evaluation, Preclinical; Electron Transport Complex I; Kidney; Male; Methylene Blue; Mitochondrial Diseases; Oxygen Consumption; Pancreas; Pancreatitis; Rats, Wistar; Urea

2016
Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant-like effect of Wuling mycelia powder in rat.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 78

    Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Feeding Behavior; Food Preferences; Hippocampus; Indazoles; Male; Methylene Blue; Mycelium; Nitric Oxide; Powders; Rats, Sprague-Dawley; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Sucrose

2016
Use of photodynamic therapy and chitosan for inactivacion of Candida albicans in a murine model.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2016, Volume: 45, Issue:8

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis, Oral; Chitosan; Disease Models, Animal; Epithelium; Female; Methylene Blue; Mice; Mice, Inbred DBA; Mucous Membrane; Nystatin; Photochemotherapy; Photosensitizing Agents; Random Allocation

2016
Methylene blue inhibits lumefantrine-resistant Plasmodium berghei.
    Journal of infection in developing countries, 2016, Jun-30, Volume: 10, Issue:6

    Topics: Animals; Antimalarials; Disease Models, Animal; Drug Resistance; Drug-Related Side Effects and Adverse Reactions; Enzyme Inhibitors; Ethanolamines; Female; Fluorenes; Lumefantrine; Malaria; Male; Methylene Blue; Mice; Parasitemia; Plasmodium berghei; Pyrimethamine; Survival Analysis; Treatment Outcome

2016
Preservation of neuromuscular function in symptomatic SOD1-G93A mice by peripheral infusion of methylene blue.
    Experimental neurology, 2016, Volume: 285, Issue:Pt A

    Topics: Amyotrophic Lateral Sclerosis; Animals; Bungarotoxins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Enzyme Inhibitors; Fluorescent Antibody Technique; Humans; Methylene Blue; Mice; Mice, Transgenic; Motor Endplate; Muscle Contraction; Neuromuscular Junction Diseases; Superoxide Dismutase

2016
Methylene blue improves streptozotocin-induced memory deficit by restoring mitochondrial function in rats.
    Brain research, 2017, 02-15, Volume: 1657

    Topics: Adenosine Triphosphate; Alzheimer Disease; Animals; Avoidance Learning; CA1 Region, Hippocampal; Disease Models, Animal; Drug Evaluation, Preclinical; Electron Transport Complex IV; Lipid Peroxidation; Male; Memory Disorders; Methylene Blue; Mitochondria; Neurons; Neuroprotective Agents; Nootropic Agents; Random Allocation; Rats, Sprague-Dawley; Streptozocin

2017
Effectiveness of purified methylene blue in an experimental model of Mycobacterium ulcerans infection.
    International journal of antimicrobial agents, 2017, Volume: 49, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Buruli Ulcer; Disease Models, Animal; Female; Humans; Male; Methylene Blue; Mice, Inbred BALB C; Microbial Sensitivity Tests; Nontuberculous Mycobacteria; Treatment Outcome

2017
Methylene blue improves hemodynamic shock but increases lipoperoxidation in severe acute pancreatitis pig model.
    Acta cirurgica brasileira, 2008, Volume: 23 Suppl 1

    Topics: Acute Disease; Animals; Biomarkers; Cholagogues and Choleretics; Disease Models, Animal; Drug Evaluation, Preclinical; Enteropeptidase; Enzyme Inhibitors; Hemodynamics; Lipid Peroxidation; Male; Malondialdehyde; Methylene Blue; Nitrates; Pancreatitis; Shock, Cardiogenic; Swine; Taurocholic Acid; Time Factors

2008
Effect of methylene blue on intra-abdominal adhesion formation in rats.
    International journal of surgery (London, England), 2008, Volume: 6, Issue:6

    Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Infusions, Parenteral; Male; Methylene Blue; Rats; Rats, Wistar; Tissue Adhesions

2008
Late, but not early, inhibition of soluble guanylate cyclase decreases mortality in a rat sepsis model.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:3

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Cecum; Cyclic GMP; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Female; Guanylate Cyclase; Methylene Blue; Mortality; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; RNA, Messenger; Sepsis; Vasoconstriction

2009
Methylene blue provides behavioral and metabolic neuroprotection against optic neuropathy.
    Neurotoxicity research, 2009, Volume: 15, Issue:3

    Topics: Adaptation, Ocular; Analysis of Variance; Animals; Brain; Choice Behavior; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electron Transport Complex I; Insecticides; Male; Methylene Blue; Mitochondria; NADH Dehydrogenase; Neurons; Neuroprotective Agents; Optic Nerve Diseases; Photic Stimulation; Rats; Rats, Long-Evans; Reaction Time; Retina; Rotenone; Visual Pathways

2009
Methylene blue attenuates pancreas ischemia-reperfusion (IR)-induced lung injury: a dose response study in a rat model.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2009, Volume: 13, Issue:9

    Topics: Acute Lung Injury; Allopurinol; Amylases; Analysis of Variance; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Lipase; Male; Methylene Blue; Pancreas; Probability; Pulmonary Circulation; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Xanthine Oxidase

2009
Methylene blue usage in the evaluation of traumatic necrosis in a rabbit liver injury model.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2009, Volume: 15, Issue:4

    Topics: Animals; Disease Models, Animal; Liver; Methylene Blue; Necrosis; Rabbits; Random Allocation; Staining and Labeling

2009
Preliminary study of indirect CT lymphography-guided sentinel lymph node biopsy in a tongue VX2 carcinoma model.
    International journal of oral and maxillofacial surgery, 2009, Volume: 38, Issue:12

    Topics: Animals; Carcinoma; Coloring Agents; Contrast Media; Disease Models, Animal; Feasibility Studies; Iohexol; Lymph Nodes; Lymphatic Metastasis; Lymphatic Vessels; Lymphography; Methylene Blue; Neoplasm Staging; Neoplasms, Experimental; Rabbits; Radiographic Image Enhancement; Radiography, Interventional; Random Allocation; Sentinel Lymph Node Biopsy; Tomography, X-Ray Computed; Tongue Neoplasms

2009
Contrast enhanced computed tomography can predict the glycosaminoglycan content and biomechanical properties of articular cartilage.
    Osteoarthritis and cartilage, 2010, Volume: 18, Issue:2

    Topics: Animals; Cartilage, Articular; Cattle; Compressive Strength; Contrast Media; Disease Models, Animal; Glycosaminoglycans; Methylene Blue; Osteoarthritis, Knee; Tomography, X-Ray Computed

2010
Localization of the sentinel lymph node in tongue VX2 carcinoma via indirect CT lymphography combined with methylene blue dye injection.
    Acta oto-laryngologica, 2010, Volume: 130, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Enzyme Inhibitors; Injections; Lymphography; Methylene Blue; Rabbits; Sentinel Lymph Node Biopsy; Tomography, X-Ray Computed; Tongue Neoplasms

2010
Venlafaxine involves nitric oxide modulatory mechanism in experimental model of chronic behavior despair in mice.
    Brain research, 2010, Jan-22, Volume: 1311

    Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Arginine; Caffeine; Central Nervous System Stimulants; Chronic Disease; Cyclohexanols; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Male; Methylene Blue; Mice; Mice, Inbred Strains; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Random Allocation; Swimming; Venlafaxine Hydrochloride

2010
Methylene blue: a simple marker for intraoperative detection of gastroduodenal perforations during laparoscopic pyloromyotomy.
    Surgical innovation, 2010, Volume: 17, Issue:1

    Topics: Animals; Coloring Agents; Disease Models, Animal; Duodenum; Feasibility Studies; Gastroplasty; Intestinal Perforation; Laparoscopy; Methylene Blue; Pyloric Stenosis, Hypertrophic; Pylorus; Stomach; Swine

2010
Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice.
    Epilepsy research, 2010, Volume: 89, Issue:2-3

    Topics: Animals; Anticonvulsants; Arginine; Convulsants; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Injections, Intraperitoneal; Lithium Chloride; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Phosphodiesterase Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Treatment Outcome

2010
The effect of Kashin-Beck disease-affected feed and T-2 toxin on the bone development of Wistar rats.
    International journal of rheumatic diseases, 2010, Volume: 13, Issue:3

    Topics: Age Factors; Animal Feed; Animals; Bone Development; Cartilage, Articular; Chondrocytes; Collagen; Disease Models, Animal; Female; Food Contamination; Growth Plate; Humans; Iohexol; Kashin-Beck Disease; Male; Methylene Blue; Necrosis; Rats; Rats, Wistar; T-2 Toxin; Tibia; Weaning; Weight Gain

2010
Methylene blue-mediated photodynamic inactivation as a novel disinfectant of enterovirus 71.
    The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:10

    Topics: Animals; Disease Models, Animal; Disinfectants; Enterovirus A, Human; Enterovirus Infections; Environmental Microbiology; Light; Methylene Blue; Mice; Mice, Inbred ICR; Photosensitizing Agents; Virus Inactivation

2010
Methylene blue reduces aβ levels and rescues early cognitive deficit by increasing proteasome activity.
    Brain pathology (Zurich, Switzerland), 2011, Volume: 21, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Cognition Disorders; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Male; Methylene Blue; Mice; Mice, Transgenic; Proteasome Endopeptidase Complex; tau Proteins

2011
Factors influencing tumor response to photodynamic therapy sensitized by intratumor administration of methylene blue.
    Lasers in surgery and medicine, 2010, Volume: 42, Issue:8

    Topics: Animals; Disease Models, Animal; Female; Injections; Methylene Blue; Mice; Mice, Inbred BALB C; Pharmaceutical Vehicles; Photochemotherapy; Polyethylene Glycols; Proportional Hazards Models; Skin Neoplasms; Spectrometry, Fluorescence; Water

2010
Photodynamic therapy mediated by methylene blue dye in wound healing.
    Photomedicine and laser surgery, 2010, Volume: 28, Issue:5

    Topics: Animals; Biopsy, Needle; Coloring Agents; Disease Models, Animal; Female; Immunohistochemistry; Low-Level Light Therapy; Methylene Blue; Photochemotherapy; Random Allocation; Rats; Rats, Wistar; Statistics, Nonparametric; Wound Healing; Wounds and Injuries

2010
Effects of methylene blue and volatile anesthetics on survival in a murine hemorrhage resuscitation model.
    The Journal of trauma, 2010, Volume: 69, Issue:6

    Topics: Analysis of Variance; Animals; Chi-Square Distribution; Disease Models, Animal; Fluid Therapy; Halothane; Isoflurane; Ketamine; Male; Methyl Ethers; Methylene Blue; Rats; Rats, Wistar; Resuscitation; Sevoflurane; Shock, Hemorrhagic; Survival Rate

2010
Effective photosensitization and selectivity in vivo of Candida Albicans by meso-tetra (N-methyl-4-pyridyl) porphine tetra tosylate.
    Lasers in surgery and medicine, 2011, Volume: 43, Issue:4

    Topics: Administration, Topical; Animals; Candida albicans; Candidiasis; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fluoroscopy; In Vitro Techniques; Methylene Blue; Mice; Mice, Inbred BALB C; Photochemotherapy; Photosensitivity Disorders; Photosensitizing Agents; Porphyrins; Random Allocation; Sensitivity and Specificity

2011
Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levels.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzoquinones; Brain; Cyclic GMP; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Methylene Blue; Mice; Nigella sativa; Nitric Oxide; Stress, Psychological

2011
Quantitative assessment of nipple perfusion with near-infrared fluorescence imaging.
    Annals of plastic surgery, 2013, Volume: 70, Issue:2

    Topics: Animals; Coloring Agents; Disease Models, Animal; Female; Indocyanine Green; Mastectomy; Methylene Blue; Nipples; Optical Imaging; Swine

2013
Histomorphometric and microbiological assessment of photodynamic therapy as an adjuvant treatment for periodontitis: a short-term evaluation of inflammatory periodontal conditions and bacterial reduction in a rat model.
    Photomedicine and laser surgery, 2011, Volume: 29, Issue:12

    Topics: Animals; Disease Models, Animal; Male; Methylene Blue; Periodontitis; Photochemotherapy; Photosensitizing Agents; Rats; Rats, Wistar

2011
Blue dye and red light, a dynamic combination for prophylaxis and treatment of cutaneous Candida albicans infections in mice.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:12

    Topics: Animals; Candida albicans; Candidiasis, Cutaneous; Coloring Agents; Disease Models, Animal; Female; Humans; Light; Methylene Blue; Mice; Photochemotherapy; Photosensitizing Agents; Tolonium Chloride; Treatment Outcome

2011
The effects of methylene blue on adhesion formation in a rat model of experimental peritonitis.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2011, Volume: 17, Issue:3

    Topics: Animals; Antioxidants; Colon; Disease Models, Animal; Female; Methylene Blue; Peritonitis; Rats; Rats, Wistar; Tissue Adhesions; Wound Healing

2011
Lack of effect of methylene blue in the SOD1 G93A mouse model of amyotrophic lateral sclerosis.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Disease Progression; Female; Male; Methylene Blue; Mice; Mice, Congenic; Superoxide Dismutase; Superoxide Dismutase-1; Survival Analysis; Treatment Outcome

2011
Performance benchmarks of an array-based hand-held photoacoustic probe adapted from a clinical ultrasound system for non-invasive sentinel lymph node imaging.
    Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2011, Nov-28, Volume: 369, Issue:1955

    Topics: Acoustics; Animals; Chickens; Diagnostic Imaging; Disease Models, Animal; Humans; Lymph Nodes; Lymphatic Metastasis; Methylene Blue; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Sentinel Lymph Node Biopsy; Ultrasonography

2011
Methylene blue administration in the compound 48/80-induced anaphylactic shock: hemodynamic study in pigs.
    Acta cirurgica brasileira, 2011, Volume: 26, Issue:6

    Topics: Anaphylaxis; Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Female; Hemodynamics; Methylene Blue; p-Methoxy-N-methylphenethylamine; Random Allocation; Swine; Time Factors; Vascular Resistance

2011
Effect of methylene blue on the hemodynamic instability resulting from liver ischemia and reperfusion in rabbits.
    Transplantation proceedings, 2011, Volume: 43, Issue:10

    Topics: Animals; Biomarkers; Blood Gas Analysis; Cardiovascular Agents; Disease Models, Animal; Hemodynamics; Liver; Liver Circulation; Male; Methylene Blue; Primary Graft Dysfunction; Rabbits; Reperfusion Injury; Time Factors

2011
Methylene blue administration fails to confer neuroprotection in two amyotrophic lateral sclerosis mouse models.
    Neuroscience, 2012, May-03, Volume: 209

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Blotting, Western; Disease Models, Animal; DNA-Binding Proteins; Drug Therapy, Combination; Enzyme Inhibitors; Immunohistochemistry; Lithium; Methylene Blue; Mice; Mice, Inbred C57BL; Mice, Transgenic; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1

2012
Methylene blue photodynamic therapy in malignant melanoma decreases expression of proliferating cell nuclear antigen and heparanases.
    Clinical and experimental dermatology, 2012, Volume: 37, Issue:5

    Topics: Animals; Biomarkers, Tumor; Disease Models, Animal; Enzyme Inhibitors; Female; Glucuronidase; Immunohistochemistry; Melanoma, Experimental; Methylene Blue; Mice; Mice, Nude; Photochemotherapy; Photosensitizing Agents; Proliferating Cell Nuclear Antigen; Skin Neoplasms

2012
Cellular mechanisms of plasmalemmal sealing and axonal repair by polyethylene glycol and methylene blue.
    Journal of neuroscience research, 2012, Volume: 90, Issue:5

    Topics: Animals; Antioxidants; Axons; Axotomy; Calcium; Cell Line, Tumor; Cell Membrane; Disease Models, Animal; Dithiothreitol; Dose-Response Relationship, Drug; In Vitro Techniques; Melatonin; Methylene Blue; Neuroblastoma; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Wound Healing

2012
Rapid, effective, and long-lasting behavioral recovery produced by microsutures, methylene blue, and polyethylene glycol after completely cutting rat sciatic nerves.
    Journal of neuroscience research, 2012, Volume: 90, Issue:5

    Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Electromyography; Evoked Potentials, Motor; Fluorescent Dyes; Methylene Blue; Microsurgery; Neural Conduction; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Neuropathy; Time Factors; Video Recording

2012
Effects of vascular photodynamic therapy in a newly adapted experimental rat aortic aneurysm model.
    Interactive cardiovascular and thoracic surgery, 2012, Volume: 15, Issue:1

    Topics: Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Immunohistochemistry; Male; Methylene Blue; Pancreatic Elastase; Photochemotherapy; Photosensitizing Agents; Rats; Rats, Sprague-Dawley; Time Factors

2012
Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity.
    Human molecular genetics, 2012, Aug-15, Volume: 21, Issue:16

    Topics: Animals; Animals, Genetically Modified; Axonal Transport; Blood-Brain Barrier; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Humans; Hydrazines; Methylene Blue; Mitochondria; Motor Neurons; Mutation; Neurons; Neuroprotective Agents; Phenotype; Phosphorylation; Protein Structure, Tertiary; Sensory Receptor Cells; tau Proteins; Tauopathies; Thiazoles; Vesicle-Associated Membrane Protein 1

2012
Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-08, Volume: 32, Issue:32

    Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Drosophila; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Huntingtin Protein; Huntington Disease; Kynurenic Acid; Methylene Blue; Mice; Mice, Inbred C57BL; Microscopy, Atomic Force; Mutation; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Psychomotor Performance; Rats; Rotarod Performance Test; Transfection; Trinucleotide Repeat Expansion

2012
rgpA DNA vaccine induces antibody response and prevents alveolar bone loss in experimental peri-implantitis.
    Journal of periodontology, 2013, Volume: 84, Issue:6

    Topics: Adhesins, Bacterial; Alveolar Bone Loss; Animals; Antibodies, Bacterial; Bacterial Vaccines; Coloring Agents; Cysteine Endopeptidases; Dental Implantation, Endosseous; Disease Models, Animal; Dogs; Genetic Vectors; Gingipain Cysteine Endopeptidases; Gingival Hemorrhage; Immunoglobulin A, Secretory; Immunoglobulin G; Male; Methylene Blue; Osseointegration; Peri-Implantitis; Periodontal Pocket; Plasmids; Porphyromonas gingivalis; Random Allocation; Saliva; Salivary Proteins and Peptides; Vaccination; Vaccines, DNA; Vaccines, Inactivated

2013
Macroscopic and pathological assessment of methylene blue and normal saline on postoperative adhesion formation in a rat cecum model.
    International journal of surgery (London, England), 2012, Volume: 10, Issue:9

    Topics: Animals; Cecal Diseases; Cecum; Disease Models, Animal; Female; Fibroblasts; Histocytochemistry; Laparotomy; Methylene Blue; Neutrophils; Postoperative Complications; Rats; Rats, Wistar; Sodium Chloride; Statistics, Nonparametric; Tissue Adhesions

2012
Influence of methylene blue on microglia-induced inflammation and motor neuron degeneration in the SOD1(G93A) model for ALS.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Cell Survival; Cytokines; Disease Models, Animal; Disease Progression; Female; Inflammation; Male; Methylene Blue; Mice; Microglia; Motor Activity; Motor Neurons; Superoxide Dismutase; Superoxide Dismutase-1; Time Factors

2012
The in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine.
    Memorias do Instituto Oswaldo Cruz, 2012, Volume: 107, Issue:6

    Topics: Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Malaria; Male; Methylene Blue; Mice; Plasmodium berghei; Pyrimethamine; Quinine

2012
Methylene blue protects liver oxidative capacity after gut ischaemia-reperfusion in the rat.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2013, Volume: 45, Issue:2

    Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Biomarkers; Cytoprotection; Disease Models, Animal; DNA Fragmentation; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; L-Lactate Dehydrogenase; Lactic Acid; Male; Mesentery; Methylene Blue; Mitochondria, Liver; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury; Time Factors

2013
Mechanistic basis of phenothiazine-driven inhibition of Tau aggregation.
    Angewandte Chemie (International ed. in English), 2013, Mar-18, Volume: 52, Issue:12

    Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Cysteine; Disease Models, Animal; Humans; Magnetic Resonance Spectroscopy; Methylene Blue; Oxidation-Reduction; Phenothiazines; Protein Binding; tau Proteins

2013
Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep.
    The European respiratory journal, 2002, Volume: 20, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Disease Models, Animal; Endotoxins; Extravascular Lung Water; Female; Lung; Male; Methylene Blue; Probability; Prostaglandin-Endoperoxide Synthases; Pulmonary Circulation; Pulmonary Edema; Random Allocation; Reference Values; Sensitivity and Specificity; Sheep; Thromboxane B2

2002
Use of methylene blue and N,O-carboxymethylchitosan to prevent postoperative adhesions in a rat uterine horn model.
    Fertility and sterility, 2003, Volume: 80 Suppl 2

    Topics: Adjuvants, Pharmaceutic; Animals; Chitin; Chitosan; Disease Models, Animal; Female; Methylene Blue; Postoperative Complications; Random Allocation; Rats; Rats, Wistar; Tissue Adhesions; Uterus

2003
Effects of diazeniumdiolates (NONOates) and methylene blue on the reduction of postoperative adhesion in rats.
    Gynecologic and obstetric investigation, 2004, Volume: 57, Issue:4

    Topics: Animals; Chitin; Chitosan; Disease Models, Animal; Female; Methylene Blue; Peritoneal Diseases; Postoperative Complications; Random Allocation; Rats; Rats, Wistar; Severity of Illness Index; Tissue Adhesions; Uterus

2004
Early glucose and methylene blue are effective against unripe ackee apple (Blighia sapida) poisoning in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2004, Volume: 42, Issue:5

    Topics: Animals; Blighia; Brain Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Fruit; Glucose; Humans; Injections, Intraperitoneal; Male; Methylene Blue; Mice; Plant Poisoning; Random Allocation; Time Factors; Treatment Outcome

2004
The effect on the intestines of continuous release of methylene blue from a drug delivery system: an experimental study in a chick embryo gastroschisis model.
    Pediatric surgery international, 2004, Volume: 20, Issue:8

    Topics: Administration, Topical; Amniotic Fluid; Animals; Chick Embryo; Disease Models, Animal; Drug Delivery Systems; Enzyme Inhibitors; Ganglia, Autonomic; Gastrointestinal Motility; Gastroschisis; Intestinal Diseases; Intestines; Methylene Blue; Nitric Oxide Synthase

2004
[Role of nitric oxide and lipid peroxidation in pathogenesis of acute experimental pancreatitis].
    Klinichna khirurhiia, 2005, Issue:1

    Topics: Animals; Arginine; Disease Models, Animal; Lipid Peroxidation; Lipid Peroxides; Male; Methylene Blue; Nitrates; Nitric Oxide; Nitrites; Pancreatitis, Acute Necrotizing; Rats; Rats, Wistar

2005
Validation of a method for localised microinjection of drugs into thalamic subregions in rats for epilepsy pharmacological studies.
    Journal of neuroscience methods, 2005, Aug-15, Volume: 146, Issue:2

    Topics: Animals; Anticonvulsants; Coloring Agents; Diffusion; Disease Models, Animal; Drug Delivery Systems; Electroencephalography; Epilepsy; Female; Genetic Predisposition to Disease; Intralaminar Thalamic Nuclei; Methylene Blue; Microinjections; Rats; Rats, Mutant Strains; Reproducibility of Results; Stereotaxic Techniques; Thalamus; Ventral Thalamic Nuclei

2005
Noninvasive in vivo monitoring of methemoglobin formation and reduction with broadband diffuse optical spectroscopy.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 100, Issue:2

    Topics: Animals; Disease Models, Animal; Hemoglobins; Kinetics; Methemoglobin; Methemoglobinemia; Methylene Blue; Oxidation-Reduction; Oxyhemoglobins; Photons; Rabbits; Scattering, Radiation; Sodium Nitrite; Spectroscopy, Near-Infrared

2006
Trypanocidal activity of methylene blue. Evidence for in vitro efficacy and in vivo failure.
    Chemotherapy, 2006, Volume: 52, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Inhibitory Concentration 50; Methylene Blue; Mice; Treatment Failure; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2006
Pre-clinical in vitro and in vivo studies to examine the potential use of photodynamic therapy in the treatment of osteomyelitis.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2006, Volume: 5, Issue:1

    Topics: Aminolevulinic Acid; Animals; Biofilms; Cell Survival; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Implants, Experimental; In Vitro Techniques; Light; Luminescent Measurements; Methylene Blue; Osteomyelitis; Photochemotherapy; Photosensitizing Agents; Rats; Rats, Sprague-Dawley; Staphylococcus aureus

2006
Methylene blue prevents neurodegeneration caused by rotenone in the retina.
    Neurotoxicity research, 2006, Volume: 9, Issue:1

    Topics: Analysis of Variance; Animals; Brain; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Transport Complex IV; Enzyme Inhibitors; In Vitro Techniques; Lipid Peroxidation; Male; Methylene Blue; Mice; Mice, Inbred CBA; Models, Biological; Neurons; Oxygen Consumption; Retinal Degeneration; Rotenone; Staining and Labeling

2006
The effects of methylene blue on lung injury in septic rats.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2006, Volume: 38, Issue:1

    Topics: Animals; Anti-Infective Agents; Catalase; Disease Models, Animal; Female; Glutathione Peroxidase; Half-Life; Lipid Peroxidation; Methylene Blue; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Sepsis; Superoxide Dismutase

2006
Sildenafil induces hyperalgesia via activation of the NO-cGMP pathway in the rat neuropathic pain model.
    Inflammopharmacology, 2006, Volume: 14, Issue:1-2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Chronic Disease; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Injections, Spinal; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Pain Threshold; Piperazines; Purines; Rats; Rats, Wistar; Sciatic Neuropathy; Signal Transduction; Sildenafil Citrate; Sulfones

2006
Methylene blue prevents surgery-induced peritoneal adhesions but impairs the early phase of anastomotic wound healing.
    Canadian journal of surgery. Journal canadien de chirurgie, 2006, Volume: 49, Issue:5

    Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Follow-Up Studies; Laparotomy; Male; Methylene Blue; Nitric Oxide Synthase; Peritoneal Diseases; Peritoneum; Postoperative Complications; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Treatment Outcome; Wound Healing

2006
[The assessment of intravital staining of parotic gland using methylene blue in the surgery of benign gland tumors--preliminary report].
    Otolaryngologia polska = The Polish otolaryngology, 2006, Volume: 60, Issue:4

    Topics: Adult; Animals; Disease Models, Animal; Facial Nerve Injuries; Female; Humans; Injections, Intralesional; Male; Methylene Blue; Middle Aged; Parotid Gland; Parotid Neoplasms; Rabbits; Staining and Labeling

2006
Intraventricular administration of gabapentin in the rat increases flurothyl seizure threshold.
    Neuroscience letters, 2007, May-07, Volume: 417, Issue:3

    Topics: Amines; Animals; Anticonvulsants; Brain; Brain Chemistry; Cerebral Cortex; Convulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsy; Flurothyl; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraventricular; Methylene Blue; Nerve Fibers, Myelinated; Rats; Rats, Sprague-Dawley; Seizures; Staining and Labeling; Time Factors; Treatment Outcome

2007
The effects of methylene blue on renal scarring due to pyelonephritis in rats.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:7

    Topics: Animals; Anti-Infective Agents; Anti-Infective Agents, Urinary; Cicatrix; Ciprofloxacin; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Escherichia coli Infections; Escherichia coli K12; Female; Injections, Intraperitoneal; Kidney; Methylene Blue; Pyelonephritis; Rats; Rats, Sprague-Dawley

2007
Cardio-cerebral and metabolic effects of methylene blue in hypertonic sodium lactate during experimental cardiopulmonary resuscitation.
    Resuscitation, 2007, Volume: 75, Issue:1

    Topics: Animals; Brain; Cardiopulmonary Resuscitation; Cerebrovascular Circulation; Coronary Circulation; Disease Models, Animal; Enzyme Inhibitors; Heart; Heart Arrest; Hypertonic Solutions; Methylene Blue; Myocardium; Sodium Lactate; Swine

2007
Methylene blue increases contralateral testicular ischaemia-reperfusion injury after unilateral testicular torsion.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:1

    Topics: Animals; Creatine Kinase; Disease Models, Animal; Enzyme Inhibitors; Male; Malondialdehyde; Methylene Blue; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion; Testicular Diseases; Testis; Time Factors; Xanthine Oxidase

2008
[Effects of methylene blue on refractory hemorrhagic shock].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2008, Volume: 30, Issue:2

    Topics: Animals; Blood Pressure; Disease Models, Animal; Female; Interleukin-6; Interleukin-8; Lactic Acid; Male; Methylene Blue; Nitric Oxide; Rabbits; Random Allocation; Shock, Hemorrhagic; Survival Rate; Tumor Necrosis Factor-alpha

2008
Cross-linking of lens crystallins in a photodynamic system: a process mediated by singlet oxygen.
    Science (New York, N.Y.), 1980, Jun-13, Volume: 208, Issue:4449

    Topics: Aging; Animals; Cataract; Cattle; Crystallins; Disease Models, Animal; Fluorescence; Light; Methylene Blue; Oxidation-Reduction; Oxygen; Photochemistry; Riboflavin; Rose Bengal

1980
Alterations of ex vivo vascular reactivity in intraperitoneal sepsis.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:5

    Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Temperature; Cecum; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Sepsis; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

1994
Hypoxia causes an abnormal contractile response in the atherosclerotic rabbit aorta. Implication of reduced nitric oxide and cGMP production.
    Circulation research, 1993, Volume: 72, Issue:3

    Topics: Animals; Aorta; Arginine; Arteriosclerosis; Calcium; Cell Hypoxia; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Male; Methylene Blue; Nitric Oxide; Nitroarginine; Rabbits; Serotonin; Vasoconstriction

1993
Establishment of a rabbit short-term dry eye model.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Winter, Volume: 11, Issue:4

    Topics: Animals; Chondroitin Sulfates; Coloring Agents; Cornea; Desiccation; Disease Models, Animal; Dry Eye Syndromes; Epithelium; Male; Methylene Blue; Microscopy, Electron, Scanning; Ophthalmic Solutions; Rabbits

1995
Targeting disseminated melanoma with radiolabelled methylene blue: Comparative bio-distribution studies in man and animals.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:3

    Topics: Adult; Aged; Animals; Brain; Coloring Agents; Disease Models, Animal; Eye; Female; Humans; Injections, Intravenous; Iodine Radioisotopes; Kidney; Liver; Male; Melanoma; Methylene Blue; Mice; Mice, Nude; Middle Aged; Neoplasm Transplantation; Time Factors; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Transplantation, Heterologous

1996
Investigations of the function of the vascular endothelium in portal hypertensive rats.
    Pharmacology, 1995, Volume: 51, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Analysis of Variance; Animals; Coloring Agents; Disease Models, Animal; Endothelium, Vascular; Hypertension, Portal; Male; Mesenteric Arteries; Methylene Blue; Microspheres; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Wistar; Thromboxane A2; Vasoconstrictor Agents

1995
The role of nitric oxide in modulating ischaemia-induced arrhythmias in rats.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:4

    Topics: Analysis of Variance; Animals; Arrhythmias, Cardiac; Blood Pressure; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Ischemic Preconditioning, Myocardial; Male; Methylene Blue; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sydnones; Vasodilator Agents; Ventricular Fibrillation

1997
Endothelial dysfunction in the perfused kidney from the streptozotocin-induced diabetic rat.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 96, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Animals; Anticoagulants; Arachidonic Acids; Biological Factors; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Indomethacin; Kidney; Male; Methoxamine; Methylene Blue; Nicardipine; Nitroarginine; Nitroprusside; Rats; Rats, Wistar; Streptozocin; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

1997
Rapid development of nitric oxide-induced hyperalgesia depends on an alternate to the cGMP-mediated pathway in the rat neuropathic pain model.
    Brain research, 1998, May-11, Volume: 792, Issue:2

    Topics: Animals; Antidotes; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hemoglobins; Hot Temperature; Hyperalgesia; Ligation; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Pain; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord

1998
Mechanism of purgative effect of magnesium sulphate on mouse colon.
    Journal of diarrhoeal diseases research, 1997, Volume: 15, Issue:4

    Topics: Animals; Anthracenes; Cathartics; Chloride Channels; Colon; Diarrhea; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Indomethacin; Intestinal Mucosa; Magnesium Sulfate; Male; Mesalamine; Methylene Blue; Mice; Mice, Inbred Strains; Premedication; Random Allocation; Reference Values; Sodium Chloride

1997
Methylene blue prevents pulmonary injury after intestinal ischemia-reperfusion.
    The Journal of trauma, 1998, Volume: 45, Issue:2

    Topics: Animals; Antioxidants; Disease Models, Animal; Drug Evaluation, Preclinical; Intestines; Leukocyte Count; Male; Methylene Blue; Neutrophils; Organ Size; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Xanthine Oxidase

1998
Evidence of involvement of guanylate cyclase in the prolongation of caeco-colonic transit time by indomethacin in mice.
    Journal of diarrhoeal diseases research, 1998, Volume: 16, Issue:4

    Topics: Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Gastrointestinal Motility; Gastrointestinal Transit; Guanylate Cyclase; Indomethacin; Male; Methylene Blue; Mice; Reference Values

1998
Transmyocardial laser revascularisation has no beneficial effect on high energy phosphates and lactate content during acute myocardial ischaemia in pigs.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1999, Volume: 16, Issue:2

    Topics: Acute Disease; Animals; Biopsy; Chromatography, High Pressure Liquid; Coloring Agents; Disease Models, Animal; Heart Atria; Injections; Lactic Acid; Laser Therapy; Male; Methylene Blue; Myocardial Ischemia; Myocardial Revascularization; Phosphates; Swine

1999
Multiple organ dysfunction after remote circulatory arrest: common pathway of radical oxygen species?
    The Journal of trauma, 1999, Volume: 47, Issue:4

    Topics: Allopurinol; Animals; Aorta; Coronary Vessels; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Heart Arrest; In Vitro Techniques; Liver; Lung; Male; Mannitol; Methylene Blue; Multiple Organ Failure; Multiple Trauma; Myocardium; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Xanthine Oxidase

1999
The VX2 carcinoma in the rabbit auricle as an experimental model for intra-arterial embolization of head and neck squamous cell carcinoma with dextran microspheres.
    Laboratory animals, 1999, Volume: 33, Issue:2

    Topics: Animals; Bone Marrow; Carcinoma, Squamous Cell; Dextrans; Disease Models, Animal; Ear Neoplasms; Ear, External; Embolization, Therapeutic; Female; Head and Neck Neoplasms; Hydrogels; Lung; Lymph Nodes; Methylene Blue; Microspheres; Neoplasm Transplantation; Rabbits; Specific Pathogen-Free Organisms; Spleen; Tumor Cells, Cultured

1999
Methylene blue mediated photodynamic therapy in experimental colorectal tumors in mice.
    Journal of photochemistry and photobiology. B, Biology, 2000, Volume: 57, Issue:2-3

    Topics: Adenocarcinoma; Animals; Colorectal Neoplasms; Disease Models, Animal; Female; Humans; Methylene Blue; Mice; Mice, Nude; Photochemotherapy; Photosensitizing Agents

2000
Methylene blue abolishes aortal tone impairment induced by liver ischemia-reperfusion in a dose response manner: an isolated-perfused double-organ rat model study.
    Shock (Augusta, Ga.), 2001, Volume: 15, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Isosorbide Dinitrate; Liver; Male; Methylene Blue; Phenylephrine; Rats; Rats, Wistar; Reperfusion Injury; Vasodilation; Vasodilator Agents

2001
Methylene blue reduces lung fluid filtration during the early phase of endotoxemia in awake sheep.
    Critical care medicine, 2001, Volume: 29, Issue:2

    Topics: Animals; Body Temperature; Capillary Permeability; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxemia; Escherichia coli Infections; Female; Guanylate Cyclase; Hemodynamics; Injections, Intravenous; Male; Methylene Blue; Nitric Oxide Synthase; Prospective Studies; Pulmonary Circulation; Random Allocation; Respiratory Distress Syndrome; Sheep; Time Factors; Vascular Resistance; Wakefulness

2001
Effect of methylene blue on resuscitation after haemorrhagic shock.
    The European journal of surgery = Acta chirurgica, 2001, Volume: 167, Issue:10

    Topics: Analysis of Variance; Animals; Cardiopulmonary Resuscitation; Disease Models, Animal; Male; Methylene Blue; Multivariate Analysis; Random Allocation; Rats; Rats, Wistar; Reference Values; Shock, Hemorrhagic; Treatment Outcome

2001
Treatment of oral candidiasis with methylene blue-mediated photodynamic therapy in an immunodeficient murine model.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2002, Volume: 93, Issue:2

    Topics: Animals; Antifungal Agents; Azoles; Candida albicans; Candidiasis, Oral; Colony Count, Microbial; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Methylene Blue; Mice; Mice, Nude; Mice, SCID; Photochemotherapy; Photosensitizing Agents

2002
Pneumocystis carinii pneumonia. An approach to rapid laboratory diagnosis.
    American journal of clinical pathology, 1979, Volume: 72, Issue:1

    Topics: Animals; Azure Stains; Clinical Laboratory Techniques; Disease Models, Animal; Methenamine; Methylene Blue; Pneumonia, Pneumocystis; Rats; Silver Nitrate; Staining and Labeling; Tolonium Chloride

1979
A survey of the effect of some drugs, chemicals, and enzymes on calcium oxalate precipitation in the rat kidney.
    Investigative urology, 1978, Volume: 15, Issue:6

    Topics: Animals; Calcium; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Folic Acid; Hydrochlorothiazide; Methylene Blue; Muramidase; Neuraminidase; Oxalates; Phosphates; Rats; Trypan Blue; Urinary Calculi; Vitamin A

1978
[Effect of nutrition on composition of calculi in the animal experiment. III. Cation exchangers, anthraquinones, diphosphates, methylene blue].
    Zeitschrift fur Urologie und Nephrologie, 1977, Volume: 70, Issue:5

    Topics: Animals; Anthraquinones; Cation Exchange Resins; Diphosphonates; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Ion Exchange Resins; Male; Methylene Blue; Rabbits; Urinary Bladder Calculi

1977
Comparative effects of anticalculus management in the rat.
    Investigative urology, 1976, Volume: 14, Issue:2

    Topics: Animals; Disease Models, Animal; Hydrochlorothiazide; Kidney Calculi; Magnesium Oxide; Male; Methylene Blue; Oxalates; Phosphates; Rats

1976
[The vasospasmolytic effects of nicorandil, cromakalim and pinacidil on 3,4-diaminopyridine-induced phasic contractions in canine coronary arteries as an experimental vasospasm model].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:4

    Topics: 4-Aminopyridine; Amifampridine; Animals; Benzopyrans; Coronary Vasospasm; Cromakalim; Disease Models, Animal; Dogs; Female; Glyburide; Guanidines; In Vitro Techniques; Ion Channel Gating; Male; Methylene Blue; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents

1992
Erythrocyte glucose-6-phosphate dehydrogenase and glutathione deficiency in sheep.
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1972, Volume: 36, Issue:1

    Topics: Age Factors; Animals; Chromium Isotopes; Disease Models, Animal; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Hemolysis; Male; Methylene Blue; Nitrofurantoin; Primaquine; Pyrimethamine; Sex Factors; Sheep

1972
Pancreatic function after normothermic ischemia. I. In vivo ischemia.
    American journal of surgery, 1970, Volume: 120, Issue:6

    Topics: Amylases; Animals; Blood Glucose; Body Temperature; Disease Models, Animal; Dogs; Drug Tolerance; Female; Glucose Tolerance Test; Insulin; Ischemia; Male; Methylene Blue; Pancreas; Pancreatic Diseases; Tolbutamide

1970