Page last updated: 2024-08-23

methyldopa and Hypotension

methyldopa has been researched along with Hypotension in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199038 (86.36)18.7374
1990's3 (6.82)18.2507
2000's2 (4.55)29.6817
2010's1 (2.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, TY; Joynt, GM1
Chan, TY; Cheng, CA; Gomersall, CD; Woo, J1
PESSINA, G1
BADOUAL, J1
SCHAER, H; ZIEGLER, WH1
SMIRK, H1
ALEKSANDROW, D; JANUSZEWICZ, W; WOCIAL, B1
CHRISTENSEN, JA; PILLSBURY, PL1
BOETTIGER, LE; MALMBORG, RO; MICHAELI, EW1
DALMAU-CIRIA, M1
FRITEL, D; MILLIEZ, P; REY, LP1
Abdel-Rahman, AA; El-Mas, MM1
Fleminger, R; Paykel, ES; Watson, JP1
Eliahou, HE; Iaina, A1
Baum, T; Moran, RM; Sabin, C1
Head, GA; Sannajust, F1
Kamdod, MA; Stephen, PM; Tyagi, MG1
Gantenberg, NS; Járai, Z; Kunos, G; Lazar-Wesley, E; Li, SJ; Scanlon, MN; Varga, K1
Gloss, D; Jick, H; Lawson, DH1
DeBard, ML1
de Jong, W; de Lang, H; Roording, P; Van Giersbergen, PL1
de Jong, W; van Giersbergen, PL1
Chalmers, JP; Kapoor, V; Mills, E; Minson, JB; Pilowsky, PM; West, MJ1
Heise, A; Kroneberg, G2
Bauer, GE1
Mitha, S; Ramasar, R; Seedat, YK; Vawda, EI1
Henning, M; van Zwieten, PA1
Robson, RD1
Bolme, P; Fuxe, K; Lidbrink, P1
Alpert, JS; Black, H; Cohn, LH; Collins, JJ; Dalen, JE1
Heinrich, F1
Becker, PF; Ceneviva, R; Ceribelli, JR; Guimarães, AS1
Carstens, E1
Doyle, AE; Ebringer, A; Jerums, G1
Calne, DB; Petrie, A; Rao, S; Reid, JL; Vakil, SD1
Peters, DK; Sevitt, LH1
Greaney, JF; Klerman, GL; Mosher, LR1
Herkert, EE; Keup, W1
Gottstein, U1
Gillam, PM; Prichard, BN1
Lamont, NM; Posel, K1
Bhargava, KP; Jaju, BP; Tangri, KK1

Reviews

4 review(s) available for methyldopa and Hypotension

ArticleYear
Psychiatric side effects of antihypertensive drugs other than reserpine.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Anxiety; Bethanidine; Clonidine; Debrisoquin; Depression; Dreams; Drug Interactions; Female; Ganglionic Blockers; Guanethidine; Hallucinations; Humans; Hydralazine; Hypotension; Male; Mental Disorders; Mental Processes; Methyldopa; Propranolol; Psychotropic Drugs; Sleep; Veratrum Alkaloids

1982
From beta blockers to Ca2+ blockers in hypertension: a review.
    Israel journal of medical sciences, 1982, Volume: 18, Issue:7

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Circulation; Drug Therapy, Combination; Humans; Hypertension; Hypotension; Methyldopa; Nifedipine; Vascular Resistance; Verapamil

1982
Central serotonergic mechanisms in hypertension.
    American journal of hypertension, 1988, Volume: 1, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Blood Pressure; Central Nervous System; Electric Stimulation; Glutamates; Hypertension; Hypotension; Kainic Acid; Methyldopa; Neurons; Rats; Serotonin

1988
On the function of central catecholamine neurons--their role in cardiovascular and arousal mechanisms.
    Research communications in chemical pathology and pharmacology, 1972, Volume: 4, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Bradycardia; Brain; Cardiovascular Physiological Phenomena; Catecholamines; Cats; Cerebral Cortex; Clonidine; Dihydroxyphenylalanine; Dopamine; Electric Stimulation; Hypotension; Methyldopa; Neurons; Norepinephrine; Receptors, Cholinergic; Stimulation, Chemical

1972

Trials

3 trial(s) available for methyldopa and Hypotension

ArticleYear
A comparison of guanacline with methyldopa in the treatment of hypertension.
    The Medical journal of Australia, 1968, Sep-14, Volume: 2, Issue:11

    Topics: Adult; Aged; Blood Pressure; Chlorothiazide; Clinical Trials as Topic; Drug Synergism; Female; Humans; Hypertension; Hypotension; Male; Methyldopa; Middle Aged; Parotid Gland; Pyridines; Vertigo

1968
Action of L- -methyldopa-hydrazine on the blood pressure of patients receiving levodopa.
    British journal of pharmacology, 1972, Volume: 44, Issue:1

    Topics: Adult; Aged; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Female; Humans; Hydrazines; Hypotension; Male; Methyldopa; Middle Aged; Parkinson Disease; Pulse

1972
A clinical trial of alpha-methyldopa in elated states.
    The American journal of psychiatry, 1966, Volume: 122, Issue:10

    Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Humans; Hypotension; Male; Methyldopa; Middle Aged

1966

Other Studies

37 other study(ies) available for methyldopa and Hypotension

ArticleYear
Prolonged profound hypotension complicating severe methyldopa overdose.
    International journal of clinical pharmacology and therapeutics, 2014, Volume: 52, Issue:7

    Topics: Antihypertensive Agents; Drug Overdose; Female; Humans; Hypotension; Methyldopa; Middle Aged

2014
Overdose of methyldopa, indapamide and theophylline resulting in prolonged hypotension, marked diuresis and hypokalaemia in an elderly patient.
    Pharmacoepidemiology and drug safety, 2009, Volume: 18, Issue:10

    Topics: Acetaminophen; Aged, 80 and over; Analgesics, Non-Narcotic; Antihypertensive Agents; Combined Modality Therapy; Critical Care; Diuresis; Drug Overdose; Fluid Therapy; Hemodynamics; Humans; Hypokalemia; Hypotension; Indapamide; Infusions, Intravenous; Male; Methyldopa; Norepinephrine; Plasma Substitutes; Polygeline; Suicide, Attempted; Theophylline; Treatment Outcome; Vasoconstrictor Agents

2009
[alpha-Methyl-dopa, new drug with hypotensive action].
    Bollettino chimico farmaceutico, 1962, Volume: 101

    Topics: Antihypertensive Agents; Humans; Hypotension; Methyldopa

1962
[New hypotensive medications: guanethidine, alphamethyldopa, mecamylamine].
    Vie medicale (Paris, France : 1920), 1963, Volume: 44

    Topics: Antihypertensive Agents; Guanethidine; Humans; Hypotension; Mecamylamine; Methyldopa

1963
[The effect of intravenously administered DOPA on the blood pressure in pretreated alpha-methyl-DOPA hypertensives. Studies on the blood pressure-lowering mechanism of alpha-methyl-DOPA].
    Klinische Wochenschrift, 1962, Sep-15, Volume: 40

    Topics: Antihypertensive Agents; Blood Pressure; Carboxy-Lyases; Dihydroxyphenylalanine; Hypertension; Hypotension; Methyldopa; Norepinephrine

1962
Hypotensive action methyldopa.
    British medical journal, 1963, Jan-19, Volume: 1, Issue:5324

    Topics: Antihypertensive Agents; Hypotension; Methyldopa

1963
[Evaluation of the hypotensive effect of aldomet (alpha-methyl DOPA) in the treatment of arterial hypertension, with reference to its effect on the metabolism of catecholamines].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1962, Nov-19, Volume: 17

    Topics: Catecholamines; Dihydroxyphenylalanine; Hypertension; Hypotension; Methyldopa

1962
TREATMENT OF HYPERTENSION. AN EVALUATION OF ALPHA-METHYLDOPA.
    California medicine, 1963, Volume: 99

    Topics: Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Double-Blind Method; Essential Hypertension; Humans; Hypertension; Hypotension; Methyldopa; Placebos; Sodium Chloride Symporter Inhibitors

1963
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY].
    Nordisk medicin, 1964, Apr-23, Volume: 71

    Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine; Hemiplegia; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Methyldopa; Neurologic Manifestations; Reserpine; Toxicology

1964
[NEW HYPOTENSIVE DRUGS].
    Medicina clinica, 1964, Volume: 42

    Topics: Alkaloids; Antihypertensive Agents; Ethacrynic Acid; Humans; Hypotension; Methyldopa; Pargyline; Pharmacology; Rauwolfia

1964
[CLINICAL TRIAL OF A HYPOTENSIVE DRUG: 3,4-DIHYDROXY-D-L-PHENYLALANINE OR METHYLDOPA].
    La Presse medicale, 1964, Oct-17, Volume: 72

    Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Eye Manifestations; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypotension; Hypotension, Orthostatic; Methyldopa; Phenylalanine; Toxicology

1964
Differential modulation by estrogen of alpha2-adrenergic and I1-imidazoline receptor-mediated hypotension in female rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2004, Volume: 97, Issue:4

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Blood Pressure; Estrogens; Female; Heart Rate; Hormone Replacement Therapy; Hypotension; Imidazoline Receptors; Methyldopa; Oxazoles; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Drug; Rilmenidine

2004
Comparison of hypotensive, orthostatic and sympathetic inhibitory actions of antihypertensive drugs in rats.
    Clinical and experimental hypertension, 1981, Volume: 3, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Diazepam; Guanethidine; Heart Rate; Hydralazine; Hypotension; Male; Mecamylamine; Methyldopa; Minoxidil; Phentolamine; Posture; Prazosin; Propranolol; Rats; Reserpine; Sympathetic Nervous System

1981
Rilmenidine-induced hypotension in conscious rabbits involves imidazoline-preferring receptors.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:1

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Dioxanes; Dose-Response Relationship, Drug; Female; Heart Rate; Hypotension; Idazoxan; Imidazoline Receptors; Male; Methyldopa; Oxazoles; Rabbits; Receptors, Drug; Rilmenidine

1994
Arginine vasopressin potentiates methyldopa induced hypotension in anesthetized Wistar rats.
    Indian journal of physiology and pharmacology, 1993, Volume: 37, Issue:2

    Topics: Anesthesia; Animals; Arginine Vasopressin; Blood Pressure; Drug Synergism; Female; Hypotension; Infusions, Intravenous; Male; Methyldopa; Rats; Rats, Wistar

1993
alpha-2-Adrenergic activation of proopiomelanocortin-containing neurons in the arcuate nucleus causes opioid-mediated hypotension and bradycardia.
    Neuroendocrinology, 1996, Volume: 63, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Bradycardia; Hypotension; In Situ Hybridization; Male; Methyldopa; Microinjections; Neurons; Nordefrin; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; RNA, Messenger; Yohimbine

1996
Adverse reactions to methyldopa with particular reference to hypotension.
    American heart journal, 1978, Volume: 96, Issue:5

    Topics: Adult; Age Factors; Aged; Blood Urea Nitrogen; Dose-Response Relationship, Drug; Female; Hematocrit; Humans; Hypotension; Male; Methyldopa; Middle Aged

1978
Methyldopa reaction simulating septic shock.
    Archives of internal medicine, 1979, Volume: 139, Issue:2

    Topics: Aged; Diagnosis, Differential; Female; Fever; Humans; Hypotension; Methyldopa; Shock, Septic

1979
Participation of opiate receptors located in the nucleus tractus solitarii in the hypotension induced by alpha-methyldopa.
    Brain research, 1989, Sep-25, Volume: 498, Issue:1

    Topics: Animals; Endorphins; Hypotension; Immune Sera; Medulla Oblongata; Methyldopa; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid

1989
Antagonism by naltrexone of the hypotension and bradycardia induced by alpha-methyldopa in conscious normotensive rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:1

    Topics: Animals; beta-Endorphin; Bradycardia; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Immune Sera; Male; Methyldopa; Naloxone; Naltrexone; Rats; Rats, Inbred Strains

1988
Central nervous alpha-adrenergic receptors and the mode of action of alpha-methyldopa.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 279, Issue:3

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Aorta; Blood Pressure; Catecholamines; Cats; Cerebral Ventricles; Cocaine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hypotension; Isoproterenol; Methyldopa; Norepinephrine; Perfusion; Phentolamine; Propranolol; Rats; Receptors, Adrenergic; Reserpine; Tyramine; Yohimbine

1973
Treatment of hypertension in the elderly.
    Drugs, 1974, Volume: 7, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Clonidine; Diuretics; Eye Diseases; Ganglionic Blockers; Heart Diseases; Humans; Hypertension; Hypotension; Methyldopa; Myocardial Infarction; Parasympatholytics; Phytotherapy; Plants, Medicinal; Rauwolfia; Vascular Diseases

1974
Clonidine.
    Lancet (London, England), 1969, Sep-13, Volume: 2, Issue:7620

    Topics: Antihypertensive Agents; Humans; Hypotension; Methyldopa; Physical Exertion; Posture

1969
[The central component of the blood pressure lowering effect of alpha-methyldopa in cats].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2

    Topics: Animals; Blood Pressure; Brain; Cats; Depression, Chemical; Dopamine; Hypotension; Methyldopa; Norepinephrine; Vertebral Artery

1968
Modification of the cardiovascular effects of L-dopa in anesthetized dogs by inhibitors of enzymes involved in catecholamine metabolism.
    Circulation research, 1971, Volume: 28, Issue:6

    Topics: Angiotensin II; Animals; Blood Pressure; Bradycardia; Carboxy-Lyases; Cresols; Dihydroxyphenylalanine; Dogs; Dopamine; Female; Heart Rate; Hydrazines; Hypertension; Hypotension; Male; Methyldopa; Monoamine Oxidase Inhibitors; Norepinephrine; Tachycardia; Thiocarbamates

1971
Arterial blood pressure decrease following adrenergic -receptor stimulation in the central nervous system.
    Japanese journal of pharmacology, 1972, Volume: 22

    Topics: Adrenergic alpha-Antagonists; Aniline Compounds; Animals; Arteries; Blood Pressure; Brain Stem; Cats; Cerebral Ventricles; Cholinesterase Inhibitors; Dopamine; Hypotension; Methyldopa; Neurons; Norepinephrine; Thiazines; Xylenes

1972
The treatment of malignant hypertension and hypertensive emergencies. A statement by the AMA committee on hypertension.
    JAMA, 1974, Jun-24, Volume: 228, Issue:13

    Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Diazoxide; Drug Evaluation; Emergencies; Female; Humans; Hydrazines; Hypertension, Malignant; Hypotension; Injections, Intramuscular; Injections, Intravenous; Male; Methods; Methyldopa; Pentolinium Tartrate; Phentolamine; Reserpine; Trimethaphan

1974
Dissection of the thoracic aorta. Medical or surgical therapy?
    The American journal of cardiology, 1974, Volume: 34, Issue:7

    Topics: Adult; Aged; Aorta, Thoracic; Aortic Aneurysm; Aortic Valve Insufficiency; Autonomic Agents; Blood Pressure; Female; Follow-Up Studies; Guanethidine; Heart Failure; Humans; Hypertension; Hypotension; Male; Methyldopa; Middle Aged; Pericardial Effusion; Propranolol; Reserpine; Trimethaphan

1974
[Problems in the establishment of indications for treatment of aortic (thoracic and abdominal) aneurysms, from a medical viewpoint (author's transl)].
    Langenbecks Archiv fur Chirurgie, 1974, Volume: 337

    Topics: Aged; Aorta, Abdominal; Aorta, Thoracic; Aortic Aneurysm; Aortic Rupture; Guanethidine; Humans; Hypotension; Methyldopa; Middle Aged; Prognosis; Propranolol; Reserpine; Trimethaphan

1974
[Perforation of the small intestine caused by low arterial flow as a complication of anti-hypertensive drug treatment].
    AMB : revista da Associacao Medica Brasileira, 1973, Volume: 19, Issue:8

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Humans; Hypertension; Hypotension; Intestinal Perforation; Intestine, Small; Male; Methyldopa

1973
[Antihypertensive agents].
    Die Pharmazie, 1972, Volume: 27, Issue:11

    Topics: Acetazolamide; Antihypertensive Agents; Bis-Trimethylammonium Compounds; Bretylium Compounds; Chlorisondamine; Chlorthalidone; Diuretics; Furosemide; Guanethidine; Guanidines; Hexamethonium Compounds; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Hypotension; Mecamylamine; Methyldopa; Pain; Parotid Gland; Pempidine; Phentolamine; Structure-Activity Relationship; Sulfonamides

1972
Diazoxide and hypotension.
    British medical journal, 1971, Nov-27, Volume: 4, Issue:5786

    Topics: Diazoxide; Humans; Hypotension; Hypotension, Orthostatic; Methyldopa

1971
Excretion patterns of tryptamine, indoleacetic acid, and 5-hydroxyindoleacetic acid, and their correlation with mental changes in schizophrenic patients under medication with alpha-methyldopa.
    Psychopharmacologia, 1969, Volume: 15, Issue:1

    Topics: Adult; Humans; Hydroxyindoleacetic Acid; Hypotension; Indoleacetic Acids; Male; Methyldopa; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Serotonin; Tryptamines

1969
[Therapy of circulatory disorders of the brain and spinal cord].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Age Factors; Anticoagulants; Brain Edema; Cerebral Hemorrhage; Cerebrovascular Disorders; Coronary Disease; Digitalis Glycosides; Endarterectomy; Humans; Hypertension; Hypertonic Solutions; Hypotension; Infarction; Intracranial Embolism and Thrombosis; Ischemic Attack, Transient; Methyldopa; Oxygen Inhalation Therapy; Plasma Substitutes; Reserpine; Respiratory Insufficiency; Spinal Cord; Stellate Ganglion; Subclavian Steal Syndrome; Sympatholytics; Vascular Diseases; Vasoconstrictor Agents; Vasodilator Agents

1969
Treatment of hypertension with propranolol.
    British medical journal, 1969, Jan-04, Volume: 1, Issue:5635

    Topics: Blood Pressure; Cardiac Output; Female; Guanethidine; Guanidines; Humans; Hypertension; Hypotension; Male; Methyldopa; Middle Aged; Physical Exertion; Posture; Pressoreceptors; Propranolol; Valsalva Maneuver

1969
The coronary attack: concepts on its etiology and hemodynamic management.
    American heart journal, 1969, Volume: 78, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Aspartate Aminotransferases; Biophysical Phenomena; Biophysics; Blood Flow Velocity; Blood Pressure; Cardiac Output; Coronary Disease; Digoxin; Electrocardiography; Heart; Heart Failure; Humans; Hydrocortisone; Hypotension; Isoproterenol; Lidocaine; Male; Methyldopa; Middle Aged; Models, Biological; Propranolol; Stress, Psychological; Veins

1969
Central vasomotor effects of alpha-methyl dopa.
    Canadian journal of physiology and pharmacology, 1966, Volume: 44, Issue:4

    Topics: Animals; Blood Pressure; Dogs; Electric Stimulation; Hypotension; Medulla Oblongata; Methyldopa; Vagus Nerve; Vasomotor System

1966